2-[4-[3-[(2R)-2-[6-(6-amino-3-pyridinyl)-3-pyridinyl]-3-methylbutan-2-yl]-1,2,4-oxadiazol-5-yl]pyrazol-1-yl]-N,N-dimethylacetamide;2-[[5-[3-[(2R)-2-[6-(2-aminopyrimidin-5-yl)-3-pyridinyl]-3-methylbutan-2-yl]-1,2,4-oxadiazol-5-yl]pyrazin-2-yl]-methylamino]ethanol;1-[4-[3-[(2S)-2-[6-(2-aminopyrimidin-5-yl)-3-pyridinyl]-3-methylbutan-2-yl]-1,2,4-oxadiazol-5-yl]pyrazol-1-yl]butan-2-one;5-[5-[(1R)-1-cyclopropyl-1-[5-(5-piperazin-1-ylpyrazin-2-yl)-1,2,4-oxadiazol-3-yl]ethyl]-2-pyridinyl]pyrimidin-2-amine;5-[5-[(2R)-2-[5-[1-(2-methoxyethyl)pyrazol-4-yl]-1,2,4-oxadiazol-3-yl]-3-methylbutan-2-yl]-2-pyridinyl]pyridin-2-amine

C117H134N42O9 — CID 157096404

IUPAC2-[4-[3-[(2R)-2-[6-(6-amino-3-pyridinyl)-3-pyridinyl]-3-methylbutan-2-yl]-1,2,4-oxadiazol-5-yl]pyrazol-1-yl]-N,N-dimethylacetamide;2-[[5-[3-[(2R)-2-[6-(2-aminopyrimidin-5-yl)-3-pyridinyl]-3-methylbutan-2-yl]-1,2,4-oxadiazol-5-yl]pyrazin-2-yl]-methylamino]ethanol;1-[4-[3-[(2S)-2-[6-(2-aminopyrimidin-5-yl)-3-pyridinyl]-3-methylbutan-2-yl]-1,2,4-oxadiazol-5-yl]pyrazol-1-yl]butan-2-one;5-[5-[(1R)-1-cyclopropyl-1-[5-(5-piperazin-1-ylpyrazin-2-yl)-1,2,4-oxadiazol-3-yl]ethyl]-2-pyridinyl]pyrimidin-2-amine;5-[5-[(2R)-2-[5-[1-(2-methoxyethyl)pyrazol-4-yl]-1,2,4-oxadiazol-3-yl]-3-methylbutan-2-yl]-2-pyridinyl]pyridin-2-amine
SMILESCC(C)[C@](C)(c1ccc(-c2ccc(N)nc2)nc1)c1noc(-c2cnn(CC(=O)N(C)C)c2)n1.CC(C)[C@](C)(c1ccc(-c2cnc(N)nc2)nc1)c1noc(-c2cnc(N(C)CCO)cn2)n1.CCC(=O)Cn1cc(-c2nc([C@](C)(c3ccc(-c4cnc(N)nc4)nc3)C(C)C)no2)cn1.COCCn1cc(-c2nc([C@@](C)(c3ccc(-c4ccc(N)nc4)nc3)C(C)C)no2)cn1.C[C@@](c1ccc(-c2cnc(N)nc2)nc1)(c1noc(-c2cnc(N3CCNCC3)cn2)n1)C1CC1
InChIInChI=1S/C24H26N10O.C24H28N8O2.C23H27N9O2.C23H26N8O2.C23H27N7O2/c1-24(16-2-3-16,17-4-5-18(27-12-17)15-10-30-23(25)31-11-15)22-32-21(35-33-22)19-13-29-20(14-28-19)34-8-6-26-7-9-34;1-15(2)24(3,18-7-8-19(26-12-18)16-6-9-20(25)27-10-16)23-29-22(34-30-23)17-11-28-32(13-17)14-21(33)31(4)5;1-14(2)23(3,16-5-6-17(25-11-16)15-9-28-22(24)29-10-15)21-30-20(34-31-21)18-12-27-19(13-26-18)32(4)7-8-33;1-5-18(32)13-31-12-16(10-28-31)20-29-21(30-33-20)23(4,14(2)3)17-6-7-19(25-11-17)15-8-26-22(24)27-9-15;1-15(2)23(3,18-6-7-19(25-13-18)16-5-8-20(24)26-11-16)22-28-21(32-29-22)17-12-27-30(14-17)9-10-31-4/h4-5,10-14,16,26H,2-3,6-9H2,1H3,(H2,25,30,31);6-13,15H,14H2,1-5H3,(H2,25,27);5-6,9-14,33H,7-8H2,1-4H3,(H2,24,28,29);6-12,14H,5,13H2,1-4H3,(H2,24,26,27);5-8,11-15H,9-10H2,1-4H3,(H2,24,26)/t2*24-;3*23-/m11101/s1
InChIKeyAFGKIBOWSVYTMM-ZOJQLZGESA-N
MW2272.64 g/mol
LogP14.35
Rot. Bonds37

About 2-[4-[3-[(2R)-2-[6-(6-amino-3-pyridinyl)-3-pyridinyl]-3-methylbutan-2-yl]-1,2,4-oxadiazol-5-yl]pyrazol-1-yl]-N,N-dimethylacetamide;2-[[5-[3-[(2R)-2-[6-(2-aminopyrimidin-5-yl)-3-pyridinyl]-3-methylbutan-2-yl]-1,2,4-oxadiazol-5-yl]pyrazin-2-yl]-methylamino]ethanol;1-[4-[3-[(2S)-2-[6-(2-aminopyrimidin-5-yl)-3-pyridinyl]-3-methylbutan-2-yl]-1,2,4-oxadiazol-5-yl]pyrazol-1-yl]butan-2-one;5-[5-[(1R)-1-cyclopropyl-1-[5-(5-piperazin-1-ylpyrazin-2-yl)-1,2,4-oxadiazol-3-yl]ethyl]-2-pyridinyl]pyrimidin-2-amine;5-[5-[(2R)-2-[5-[1-(2-methoxyethyl)pyrazol-4-yl]-1,2,4-oxadiazol-3-yl]-3-methylbutan-2-yl]-2-pyridinyl]pyridin-2-amine

2-[4-[3-[(2R)-2-[6-(6-amino-3-pyridinyl)-3-pyridinyl]-3-methylbutan-2-yl]-1,2,4-oxadiazol-5-yl]pyrazol-1-yl]-N,N-dimethylacetamide;2-[[5-[3-[(2R)-2-[6-(2-aminopyrimidin-5-yl)-3-pyridinyl]-3-methylbutan-2-yl]-1,2,4-oxadiazol-5-yl]pyrazin-2-yl]-methylamino]ethanol;1-[4-[3-[(2S)-2-[6-(2-aminopyrimidin-5-yl)-3-pyridinyl]-3-methylbutan-2-yl]-1,2,4-oxadiazol-5-yl]pyrazol-1-yl]butan-2-one;5-[5-[(1R)-1-cyclopropyl-1-[5-(5-piperazin-1-ylpyrazin-2-yl)-1,2,4-oxadiazol-3-yl]ethyl]-2-pyridinyl]pyrimidin-2-amine;5-[5-[(2R)-2-[5-[1-(2-methoxyethyl)pyrazol-4-yl]-1,2,4-oxadiazol-3-yl]-3-methylbutan-2-yl]-2-pyridinyl]pyridin-2-amine (PubChem CID 157096404) has the molecular formula C117H134N42O9 and a molecular weight of 2272.64 g/mol. Its IUPAC name is 2-[4-[3-[(2R)-2-[6-(6-amino-3-pyridinyl)-3-pyridinyl]-3-methylbutan-2-yl]-1,2,4-oxadiazol-5-yl]pyrazol-1-yl]-N,N-dimethylacetamide;2-[[5-[3-[(2R)-2-[6-(2-aminopyrimidin-5-yl)-3-pyridinyl]-3-methylbutan-2-yl]-1,2,4-oxadiazol-5-yl]pyrazin-2-yl]-methylamino]ethanol;1-[4-[3-[(2S)-2-[6-(2-aminopyrimidin-5-yl)-3-pyridinyl]-3-methylbutan-2-yl]-1,2,4-oxadiazol-5-yl]pyrazol-1-yl]butan-2-one;5-[5-[(1R)-1-cyclopropyl-1-[5-(5-piperazin-1-ylpyrazin-2-yl)-1,2,4-oxadiazol-3-yl]ethyl]-2-pyridinyl]pyrimidin-2-amine;5-[5-[(2R)-2-[5-[1-(2-methoxyethyl)pyrazol-4-yl]-1,2,4-oxadiazol-3-yl]-3-methylbutan-2-yl]-2-pyridinyl]pyridin-2-amine.

Molecular Properties

Compound Name2-[4-[3-[(2R)-2-[6-(6-amino-3-pyridinyl)-3-pyridinyl]-3-methylbutan-2-yl]-1,2,4-oxadiazol-5-yl]pyrazol-1-yl]-N,N-dimethylacetamide;2-[[5-[3-[(2R)-2-[6-(2-aminopyrimidin-5-yl)-3-pyridinyl]-3-methylbutan-2-yl]-1,2,4-oxadiazol-5-yl]pyrazin-2-yl]-methylamino]ethanol;1-[4-[3-[(2S)-2-[6-(2-aminopyrimidin-5-yl)-3-pyridinyl]-3-methylbutan-2-yl]-1,2,4-oxadiazol-5-yl]pyrazol-1-yl]butan-2-one;5-[5-[(1R)-1-cyclopropyl-1-[5-(5-piperazin-1-ylpyrazin-2-yl)-1,2,4-oxadiazol-3-yl]ethyl]-2-pyridinyl]pyrimidin-2-amine;5-[5-[(2R)-2-[5-[1-(2-methoxyethyl)pyrazol-4-yl]-1,2,4-oxadiazol-3-yl]-3-methylbutan-2-yl]-2-pyridinyl]pyridin-2-amine
PubChem CID157096404
Molecular FormulaC117H134N42O9
Molecular Weight2272.64 g/mol
Exact Mass2271.13
IUPAC Name2-[4-[3-[(2R)-2-[6-(6-amino-3-pyridinyl)-3-pyridinyl]-3-methylbutan-2-yl]-1,2,4-oxadiazol-5-yl]pyrazol-1-yl]-N,N-dimethylacetamide;2-[[5-[3-[(2R)-2-[6-(2-aminopyrimidin-5-yl)-3-pyridinyl]-3-methylbutan-2-yl]-1,2,4-oxadiazol-5-yl]pyrazin-2-yl]-methylamino]ethanol;1-[4-[3-[(2S)-2-[6-(2-aminopyrimidin-5-yl)-3-pyridinyl]-3-methylbutan-2-yl]-1,2,4-oxadiazol-5-yl]pyrazol-1-yl]butan-2-one;5-[5-[(1R)-1-cyclopropyl-1-[5-(5-piperazin-1-ylpyrazin-2-yl)-1,2,4-oxadiazol-3-yl]ethyl]-2-pyridinyl]pyrimidin-2-amine;5-[5-[(2R)-2-[5-[1-(2-methoxyethyl)pyrazol-4-yl]-1,2,4-oxadiazol-3-yl]-3-methylbutan-2-yl]-2-pyridinyl]pyridin-2-amine
SMILESCC(C)[C@](C)(c1ccc(-c2ccc(N)nc2)nc1)c1noc(-c2cnn(CC(=O)N(C)C)c2)n1.CC(C)[C@](C)(c1ccc(-c2cnc(N)nc2)nc1)c1noc(-c2cnc(N(C)CCO)cn2)n1.CCC(=O)Cn1cc(-c2nc([C@](C)(c3ccc(-c4cnc(N)nc4)nc3)C(C)C)no2)cn1.COCCn1cc(-c2nc([C@@](C)(c3ccc(-c4ccc(N)nc4)nc3)C(C)C)no2)cn1.C[C@@](c1ccc(-c2cnc(N)nc2)nc1)(c1noc(-c2cnc(N3CCNCC3)cn2)n1)C1CC1
InChIInChI=1S/C24H26N10O.C24H28N8O2.C23H27N9O2.C23H26N8O2.C23H27N7O2/c1-24(16-2-3-16,17-4-5-18(27-12-17)15-10-30-23(25)31-11-15)22-32-21(35-33-22)19-13-29-20(14-28-19)34-8-6-26-7-9-34;1-15(2)24(3,18-7-8-19(26-12-18)16-6-9-20(25)27-10-16)23-29-22(34-30-23)17-11-28-32(13-17)14-21(33)31(4)5;1-14(2)23(3,16-5-6-17(25-11-16)15-9-28-22(24)29-10-15)21-30-20(34-31-21)18-12-27-19(13-26-18)32(4)7-8-33;1-5-18(32)13-31-12-16(10-28-31)20-29-21(30-33-20)23(4,14(2)3)17-6-7-19(25-11-17)15-8-26-22(24)27-9-15;1-15(2)23(3,18-6-7-19(25-13-18)16-5-8-20(24)26-11-16)22-28-21(32-29-22)17-12-27-30(14-17)9-10-31-4/h4-5,10-14,16,26H,2-3,6-9H2,1H3,(H2,25,30,31);6-13,15H,14H2,1-5H3,(H2,25,27);5-6,9-14,33H,7-8H2,1-4H3,(H2,24,28,29);6-12,14H,5,13H2,1-4H3,(H2,24,26,27);5-8,11-15H,9-10H2,1-4H3,(H2,24,26)/t2*24-;3*23-/m11101/s1
InChIKeyAFGKIBOWSVYTMM-ZOJQLZGESA-N
XLogP14.35
TPSA682.64 Ų
H-Bond Donors7
H-Bond Acceptors50
Rotatable Bonds37
Heavy Atoms168
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5002272.64
LogP ≤ 514.35
H-Bond Donors ≤ 57
H-Bond Acceptors ≤ 1050

Analyze 2-[4-[3-[(2R)-2-[6-(6-amino-3-pyridinyl)-3-pyridinyl]-3-methylbutan-2-yl]-1,2,4-oxadiazol-5-yl]pyrazol-1-yl]-N,N-dimethylacetamide;2-[[5-[3-[(2R)-2-[6-(2-aminopyrimidin-5-yl)-3-pyridinyl]-3-methylbutan-2-yl]-1,2,4-oxadiazol-5-yl]pyrazin-2-yl]-methylamino]ethanol;1-[4-[3-[(2S)-2-[6-(2-aminopyrimidin-5-yl)-3-pyridinyl]-3-methylbutan-2-yl]-1,2,4-oxadiazol-5-yl]pyrazol-1-yl]butan-2-one;5-[5-[(1R)-1-cyclopropyl-1-[5-(5-piperazin-1-ylpyrazin-2-yl)-1,2,4-oxadiazol-3-yl]ethyl]-2-pyridinyl]pyrimidin-2-amine;5-[5-[(2R)-2-[5-[1-(2-methoxyethyl)pyrazol-4-yl]-1,2,4-oxadiazol-3-yl]-3-methylbutan-2-yl]-2-pyridinyl]pyridin-2-amine with MolForge

Explore ADMET properties, 3D molecular structure, drug-likeness score, and discover similar compounds using our AI-powered platform.

Launch Full Analysis

Frequently Asked Questions

What is the IUPAC name of 2-[4-[3-[(2R)-2-[6-(6-amino-3-pyridinyl)-3-pyridinyl]-3-methylbutan-2-yl]-1,2,4-oxadiazol-5-yl]pyrazol-1-yl]-N,N-dimethylacetamide;2-[[5-[3-[(2R)-2-[6-(2-aminopyrimidin-5-yl)-3-pyridinyl]-3-methylbutan-2-yl]-1,2,4-oxadiazol-5-yl]pyrazin-2-yl]-methylamino]ethanol;1-[4-[3-[(2S)-2-[6-(2-aminopyrimidin-5-yl)-3-pyridinyl]-3-methylbutan-2-yl]-1,2,4-oxadiazol-5-yl]pyrazol-1-yl]butan-2-one;5-[5-[(1R)-1-cyclopropyl-1-[5-(5-piperazin-1-ylpyrazin-2-yl)-1,2,4-oxadiazol-3-yl]ethyl]-2-pyridinyl]pyrimidin-2-amine;5-[5-[(2R)-2-[5-[1-(2-methoxyethyl)pyrazol-4-yl]-1,2,4-oxadiazol-3-yl]-3-methylbutan-2-yl]-2-pyridinyl]pyridin-2-amine?
The IUPAC name of 2-[4-[3-[(2R)-2-[6-(6-amino-3-pyridinyl)-3-pyridinyl]-3-methylbutan-2-yl]-1,2,4-oxadiazol-5-yl]pyrazol-1-yl]-N,N-dimethylacetamide;2-[[5-[3-[(2R)-2-[6-(2-aminopyrimidin-5-yl)-3-pyridinyl]-3-methylbutan-2-yl]-1,2,4-oxadiazol-5-yl]pyrazin-2-yl]-methylamino]ethanol;1-[4-[3-[(2S)-2-[6-(2-aminopyrimidin-5-yl)-3-pyridinyl]-3-methylbutan-2-yl]-1,2,4-oxadiazol-5-yl]pyrazol-1-yl]butan-2-one;5-[5-[(1R)-1-cyclopropyl-1-[5-(5-piperazin-1-ylpyrazin-2-yl)-1,2,4-oxadiazol-3-yl]ethyl]-2-pyridinyl]pyrimidin-2-amine;5-[5-[(2R)-2-[5-[1-(2-methoxyethyl)pyrazol-4-yl]-1,2,4-oxadiazol-3-yl]-3-methylbutan-2-yl]-2-pyridinyl]pyridin-2-amine (CID 157096404) is 2-[4-[3-[(2R)-2-[6-(6-amino-3-pyridinyl)-3-pyridinyl]-3-methylbutan-2-yl]-1,2,4-oxadiazol-5-yl]pyrazol-1-yl]-N,N-dimethylacetamide;2-[[5-[3-[(2R)-2-[6-(2-aminopyrimidin-5-yl)-3-pyridinyl]-3-methylbutan-2-yl]-1,2,4-oxadiazol-5-yl]pyrazin-2-yl]-methylamino]ethanol;1-[4-[3-[(2S)-2-[6-(2-aminopyrimidin-5-yl)-3-pyridinyl]-3-methylbutan-2-yl]-1,2,4-oxadiazol-5-yl]pyrazol-1-yl]butan-2-one;5-[5-[(1R)-1-cyclopropyl-1-[5-(5-piperazin-1-ylpyrazin-2-yl)-1,2,4-oxadiazol-3-yl]ethyl]-2-pyridinyl]pyrimidin-2-amine;5-[5-[(2R)-2-[5-[1-(2-methoxyethyl)pyrazol-4-yl]-1,2,4-oxadiazol-3-yl]-3-methylbutan-2-yl]-2-pyridinyl]pyridin-2-amine.
What is the SMILES notation for 2-[4-[3-[(2R)-2-[6-(6-amino-3-pyridinyl)-3-pyridinyl]-3-methylbutan-2-yl]-1,2,4-oxadiazol-5-yl]pyrazol-1-yl]-N,N-dimethylacetamide;2-[[5-[3-[(2R)-2-[6-(2-aminopyrimidin-5-yl)-3-pyridinyl]-3-methylbutan-2-yl]-1,2,4-oxadiazol-5-yl]pyrazin-2-yl]-methylamino]ethanol;1-[4-[3-[(2S)-2-[6-(2-aminopyrimidin-5-yl)-3-pyridinyl]-3-methylbutan-2-yl]-1,2,4-oxadiazol-5-yl]pyrazol-1-yl]butan-2-one;5-[5-[(1R)-1-cyclopropyl-1-[5-(5-piperazin-1-ylpyrazin-2-yl)-1,2,4-oxadiazol-3-yl]ethyl]-2-pyridinyl]pyrimidin-2-amine;5-[5-[(2R)-2-[5-[1-(2-methoxyethyl)pyrazol-4-yl]-1,2,4-oxadiazol-3-yl]-3-methylbutan-2-yl]-2-pyridinyl]pyridin-2-amine?
The canonical SMILES for 2-[4-[3-[(2R)-2-[6-(6-amino-3-pyridinyl)-3-pyridinyl]-3-methylbutan-2-yl]-1,2,4-oxadiazol-5-yl]pyrazol-1-yl]-N,N-dimethylacetamide;2-[[5-[3-[(2R)-2-[6-(2-aminopyrimidin-5-yl)-3-pyridinyl]-3-methylbutan-2-yl]-1,2,4-oxadiazol-5-yl]pyrazin-2-yl]-methylamino]ethanol;1-[4-[3-[(2S)-2-[6-(2-aminopyrimidin-5-yl)-3-pyridinyl]-3-methylbutan-2-yl]-1,2,4-oxadiazol-5-yl]pyrazol-1-yl]butan-2-one;5-[5-[(1R)-1-cyclopropyl-1-[5-(5-piperazin-1-ylpyrazin-2-yl)-1,2,4-oxadiazol-3-yl]ethyl]-2-pyridinyl]pyrimidin-2-amine;5-[5-[(2R)-2-[5-[1-(2-methoxyethyl)pyrazol-4-yl]-1,2,4-oxadiazol-3-yl]-3-methylbutan-2-yl]-2-pyridinyl]pyridin-2-amine is CC(C)[C@](C)(c1ccc(-c2ccc(N)nc2)nc1)c1noc(-c2cnn(CC(=O)N(C)C)c2)n1.CC(C)[C@](C)(c1ccc(-c2cnc(N)nc2)nc1)c1noc(-c2cnc(N(C)CCO)cn2)n1.CCC(=O)Cn1cc(-c2nc([C@](C)(c3ccc(-c4cnc(N)nc4)nc3)C(C)C)no2)cn1.COCCn1cc(-c2nc([C@@](C)(c3ccc(-c4ccc(N)nc4)nc3)C(C)C)no2)cn1.C[C@@](c1ccc(-c2cnc(N)nc2)nc1)(c1noc(-c2cnc(N3CCNCC3)cn2)n1)C1CC1.
What is the InChIKey of 2-[4-[3-[(2R)-2-[6-(6-amino-3-pyridinyl)-3-pyridinyl]-3-methylbutan-2-yl]-1,2,4-oxadiazol-5-yl]pyrazol-1-yl]-N,N-dimethylacetamide;2-[[5-[3-[(2R)-2-[6-(2-aminopyrimidin-5-yl)-3-pyridinyl]-3-methylbutan-2-yl]-1,2,4-oxadiazol-5-yl]pyrazin-2-yl]-methylamino]ethanol;1-[4-[3-[(2S)-2-[6-(2-aminopyrimidin-5-yl)-3-pyridinyl]-3-methylbutan-2-yl]-1,2,4-oxadiazol-5-yl]pyrazol-1-yl]butan-2-one;5-[5-[(1R)-1-cyclopropyl-1-[5-(5-piperazin-1-ylpyrazin-2-yl)-1,2,4-oxadiazol-3-yl]ethyl]-2-pyridinyl]pyrimidin-2-amine;5-[5-[(2R)-2-[5-[1-(2-methoxyethyl)pyrazol-4-yl]-1,2,4-oxadiazol-3-yl]-3-methylbutan-2-yl]-2-pyridinyl]pyridin-2-amine?
The InChIKey is AFGKIBOWSVYTMM-ZOJQLZGESA-N. The full InChI is InChI=1S/C24H26N10O.C24H28N8O2.C23H27N9O2.C23H26N8O2.C23H27N7O2/c1-24(16-2-3-16,17-4-5-18(27-12-17)15-10-30-23(25)31-11-15)22-32-21(35-33-22)19-13-29-20(14-28-19)34-8-6-26-7-9-34;1-15(2)24(3,18-7-8-19(26-12-18)16-6-9-20(25)27-10-16)23-29-22(34-30-23)17-11-28-32(13-17)14-21(33)31(4)5;1-14(2)23(3,16-5-6-17(25-11-16)15-9-28-22(24)29-10-15)21-30-20(34-31-21)18-12-27-19(13-26-18)32(4)7-8-33;1-5-18(32)13-31-12-16(10-28-31)20-29-21(30-33-20)23(4,14(2)3)17-6-7-19(25-11-17)15-8-26-22(24)27-9-15;1-15(2)23(3,18-6-7-19(25-13-18)16-5-8-20(24)26-11-16)22-28-21(32-29-22)17-12-27-30(14-17)9-10-31-4/h4-5,10-14,16,26H,2-3,6-9H2,1H3,(H2,25,30,31);6-13,15H,14H2,1-5H3,(H2,25,27);5-6,9-14,33H,7-8H2,1-4H3,(H2,24,28,29);6-12,14H,5,13H2,1-4H3,(H2,24,26,27);5-8,11-15H,9-10H2,1-4H3,(H2,24,26)/t2*24-;3*23-/m11101/s1.
What are the key properties of 2-[4-[3-[(2R)-2-[6-(6-amino-3-pyridinyl)-3-pyridinyl]-3-methylbutan-2-yl]-1,2,4-oxadiazol-5-yl]pyrazol-1-yl]-N,N-dimethylacetamide;2-[[5-[3-[(2R)-2-[6-(2-aminopyrimidin-5-yl)-3-pyridinyl]-3-methylbutan-2-yl]-1,2,4-oxadiazol-5-yl]pyrazin-2-yl]-methylamino]ethanol;1-[4-[3-[(2S)-2-[6-(2-aminopyrimidin-5-yl)-3-pyridinyl]-3-methylbutan-2-yl]-1,2,4-oxadiazol-5-yl]pyrazol-1-yl]butan-2-one;5-[5-[(1R)-1-cyclopropyl-1-[5-(5-piperazin-1-ylpyrazin-2-yl)-1,2,4-oxadiazol-3-yl]ethyl]-2-pyridinyl]pyrimidin-2-amine;5-[5-[(2R)-2-[5-[1-(2-methoxyethyl)pyrazol-4-yl]-1,2,4-oxadiazol-3-yl]-3-methylbutan-2-yl]-2-pyridinyl]pyridin-2-amine?
2-[4-[3-[(2R)-2-[6-(6-amino-3-pyridinyl)-3-pyridinyl]-3-methylbutan-2-yl]-1,2,4-oxadiazol-5-yl]pyrazol-1-yl]-N,N-dimethylacetamide;2-[[5-[3-[(2R)-2-[6-(2-aminopyrimidin-5-yl)-3-pyridinyl]-3-methylbutan-2-yl]-1,2,4-oxadiazol-5-yl]pyrazin-2-yl]-methylamino]ethanol;1-[4-[3-[(2S)-2-[6-(2-aminopyrimidin-5-yl)-3-pyridinyl]-3-methylbutan-2-yl]-1,2,4-oxadiazol-5-yl]pyrazol-1-yl]butan-2-one;5-[5-[(1R)-1-cyclopropyl-1-[5-(5-piperazin-1-ylpyrazin-2-yl)-1,2,4-oxadiazol-3-yl]ethyl]-2-pyridinyl]pyrimidin-2-amine;5-[5-[(2R)-2-[5-[1-(2-methoxyethyl)pyrazol-4-yl]-1,2,4-oxadiazol-3-yl]-3-methylbutan-2-yl]-2-pyridinyl]pyridin-2-amine has a molecular weight of 2272.64 g/mol, XLogP of 14.35, 37 rotatable bonds, 7 hydrogen bond donors, and 50 hydrogen bond acceptors.
Where does this data come from?
All data for 2-[4-[3-[(2R)-2-[6-(6-amino-3-pyridinyl)-3-pyridinyl]-3-methylbutan-2-yl]-1,2,4-oxadiazol-5-yl]pyrazol-1-yl]-N,N-dimethylacetamide;2-[[5-[3-[(2R)-2-[6-(2-aminopyrimidin-5-yl)-3-pyridinyl]-3-methylbutan-2-yl]-1,2,4-oxadiazol-5-yl]pyrazin-2-yl]-methylamino]ethanol;1-[4-[3-[(2S)-2-[6-(2-aminopyrimidin-5-yl)-3-pyridinyl]-3-methylbutan-2-yl]-1,2,4-oxadiazol-5-yl]pyrazol-1-yl]butan-2-one;5-[5-[(1R)-1-cyclopropyl-1-[5-(5-piperazin-1-ylpyrazin-2-yl)-1,2,4-oxadiazol-3-yl]ethyl]-2-pyridinyl]pyrimidin-2-amine;5-[5-[(2R)-2-[5-[1-(2-methoxyethyl)pyrazol-4-yl]-1,2,4-oxadiazol-3-yl]-3-methylbutan-2-yl]-2-pyridinyl]pyridin-2-amine is sourced from PubChem (CID 157096404), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).