N,N-dimethyl-4-[[5-(3-methylphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]amino]benzamide;5-(4-ethylpiperazin-1-yl)-N-(2-ethyl-4-pyridinyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine;5-(4-ethylpiperazin-1-yl)-N-(2-methyl-4-pyridinyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine;N-(2-ethyl-4-pyridinyl)-5-(4-methoxypiperidin-1-yl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine;5-(4-methoxy-2-methylphenyl)-N-(4-morpholin-4-ylphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine;4-[[5-(3-methylphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]amino]-N-piperidin-4-ylbenzamide

C127H144N36O5 — CID 157097610

About N,N-dimethyl-4-[[5-(3-methylphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]amino]benzamide;5-(4-ethylpiperazin-1-yl)-N-(2-ethyl-4-pyridinyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine;5-(4-ethylpiperazin-1-yl)-N-(2-methyl-4-pyridinyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine;N-(2-ethyl-4-pyridinyl)-5-(4-methoxypiperidin-1-yl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine;5-(4-methoxy-2-methylphenyl)-N-(4-morpholin-4-ylphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine;4-[[5-(3-methylphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]amino]-N-piperidin-4-ylbenzamide

N,N-dimethyl-4-[[5-(3-methylphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]amino]benzamide;5-(4-ethylpiperazin-1-yl)-N-(2-ethyl-4-pyridinyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine;5-(4-ethylpiperazin-1-yl)-N-(2-methyl-4-pyridinyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine;N-(2-ethyl-4-pyridinyl)-5-(4-methoxypiperidin-1-yl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine;5-(4-methoxy-2-methylphenyl)-N-(4-morpholin-4-ylphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine;4-[[5-(3-methylphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]amino]-N-piperidin-4-ylbenzamide (PubChem CID 157097610) has the molecular formula C127H144N36O5 and a molecular weight of 2254.80 g/mol. Its IUPAC name is N,N-dimethyl-4-[[5-(3-methylphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]amino]benzamide;5-(4-ethylpiperazin-1-yl)-N-(2-ethyl-4-pyridinyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine;5-(4-ethylpiperazin-1-yl)-N-(2-methyl-4-pyridinyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine;N-(2-ethyl-4-pyridinyl)-5-(4-methoxypiperidin-1-yl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine;5-(4-methoxy-2-methylphenyl)-N-(4-morpholin-4-ylphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine;4-[[5-(3-methylphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]amino]-N-piperidin-4-ylbenzamide.

Molecular Properties

• Compound Name: N,N-dimethyl-4-[[5-(3-methylphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]amino]benzamide;5-(4-ethylpiperazin-1-yl)-N-(2-ethyl-4-pyridinyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine;5-(4-ethylpiperazin-1-yl)-N-(2-methyl-4-pyridinyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine;N-(2-ethyl-4-pyridinyl)-5-(4-methoxypiperidin-1-yl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine;5-(4-methoxy-2-methylphenyl)-N-(4-morpholin-4-ylphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine;4-[[5-(3-methylphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]amino]-N-piperidin-4-ylbenzamide
• PubChem CID: 157097610
• Molecular Formula: C127H144N36O5
• Molecular Weight: 2254.80 g/mol
• Exact Mass: 2253.21
• IUPAC Name: N,N-dimethyl-4-[[5-(3-methylphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]amino]benzamide;5-(4-ethylpiperazin-1-yl)-N-(2-ethyl-4-pyridinyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine;5-(4-ethylpiperazin-1-yl)-N-(2-methyl-4-pyridinyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine;N-(2-ethyl-4-pyridinyl)-5-(4-methoxypiperidin-1-yl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine;5-(4-methoxy-2-methylphenyl)-N-(4-morpholin-4-ylphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine;4-[[5-(3-methylphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]amino]-N-piperidin-4-ylbenzamide
• SMILES: CCN1CCN(c2cccc3nc(Nc4ccnc(C)c4)nn23)CC1.CCc1cc(Nc2nc3cccc(N4CCC(OC)CC4)n3n2)ccn1.CCc1cc(Nc2nc3cccc(N4CCN(CC)CC4)n3n2)ccn1.COc1ccc(-c2cccc3nc(Nc4ccc(N5CCOCC5)cc4)nn23)c(C)c1.Cc1cccc(-c2cccc3nc(Nc4ccc(C(=O)N(C)C)cc4)nn23)c1.Cc1cccc(-c2cccc3nc(Nc4ccc(C(=O)NC5CCNCC5)cc4)nn23)c1
• InChI: InChI=1S/C25H26N6O.C24H25N5O2.C22H21N5O.C19H25N7.C19H24N6O.C18H23N7/c1-17-4-2-5-19(16-17)22-6-3-7-23-29-25(30-31(22)23)28-20-10-8-18(9-11-20)24(32)27-21-12-14-26-15-13-21;1-17-16-20(30-2)10-11-21(17)22-4-3-5-23-26-24(27-29(22)23)25-18-6-8-19(9-7-18)28-12-14-31-15-13-28;1-15-6-4-7-17(14-15)19-8-5-9-20-24-22(25-27(19)20)23-18-12-10-16(11-13-18)21(28)26(2)3;1-3-15-14-16(8-9-20-15)21-19-22-17-6-5-7-18(26(17)23-19)25-12-10-24(4-2)11-13-25;1-3-14-13-15(7-10-20-14)21-19-22-17-5-4-6-18(25(17)23-19)24-11-8-16(26-2)9-12-24;1-3-23-9-11-24(12-10-23)17-6-4-5-16-21-18(22-25(16)17)20-15-7-8-19-14(2)13-15/h2-11,16,21,26H,12-15H2,1H3,(H,27,32)(H,28,30);3-11,16H,12-15H2,1-2H3,(H,25,27);4-14H,1-3H3,(H,23,25);5-9,14H,3-4,10-13H2,1-2H3,(H,20,21,23);4-7,10,13,16H,3,8-9,11-12H2,1-2H3,(H,20,21,23);4-8,13H,3,9-12H2,1-2H3,(H,19,20,22)
• InChIKey: AFJUVQVQNFAAPD-UHFFFAOYSA-N
• XLogP: 20.31
• TPSA: 400.56 Ų
• H-Bond Donors: 8
• H-Bond Acceptors: 39
• Rotatable Bonds: 28
• Heavy Atoms: 168
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2254.80
LogP ≤ 5	20.31
H-Bond Donors ≤ 5	8
H-Bond Acceptors ≤ 10	39

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': 'anil_di_alk_A(478)', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of N,N-dimethyl-4-[[5-(3-methylphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]amino]benzamide;5-(4-ethylpiperazin-1-yl)-N-(2-ethyl-4-pyridinyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine;5-(4-ethylpiperazin-1-yl)-N-(2-methyl-4-pyridinyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine;N-(2-ethyl-4-pyridinyl)-5-(4-methoxypiperidin-1-yl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine;5-(4-methoxy-2-methylphenyl)-N-(4-morpholin-4-ylphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine;4-[[5-(3-methylphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]amino]-N-piperidin-4-ylbenzamide?

The IUPAC name of N,N-dimethyl-4-[[5-(3-methylphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]amino]benzamide;5-(4-ethylpiperazin-1-yl)-N-(2-ethyl-4-pyridinyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine;5-(4-ethylpiperazin-1-yl)-N-(2-methyl-4-pyridinyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine;N-(2-ethyl-4-pyridinyl)-5-(4-methoxypiperidin-1-yl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine;5-(4-methoxy-2-methylphenyl)-N-(4-morpholin-4-ylphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine;4-[[5-(3-methylphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]amino]-N-piperidin-4-ylbenzamide (CID 157097610) is N,N-dimethyl-4-[[5-(3-methylphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]amino]benzamide;5-(4-ethylpiperazin-1-yl)-N-(2-ethyl-4-pyridinyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine;5-(4-ethylpiperazin-1-yl)-N-(2-methyl-4-pyridinyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine;N-(2-ethyl-4-pyridinyl)-5-(4-methoxypiperidin-1-yl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine;5-(4-methoxy-2-methylphenyl)-N-(4-morpholin-4-ylphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine;4-[[5-(3-methylphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]amino]-N-piperidin-4-ylbenzamide.

What is the SMILES notation for N,N-dimethyl-4-[[5-(3-methylphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]amino]benzamide;5-(4-ethylpiperazin-1-yl)-N-(2-ethyl-4-pyridinyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine;5-(4-ethylpiperazin-1-yl)-N-(2-methyl-4-pyridinyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine;N-(2-ethyl-4-pyridinyl)-5-(4-methoxypiperidin-1-yl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine;5-(4-methoxy-2-methylphenyl)-N-(4-morpholin-4-ylphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine;4-[[5-(3-methylphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]amino]-N-piperidin-4-ylbenzamide?

The canonical SMILES for N,N-dimethyl-4-[[5-(3-methylphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]amino]benzamide;5-(4-ethylpiperazin-1-yl)-N-(2-ethyl-4-pyridinyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine;5-(4-ethylpiperazin-1-yl)-N-(2-methyl-4-pyridinyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine;N-(2-ethyl-4-pyridinyl)-5-(4-methoxypiperidin-1-yl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine;5-(4-methoxy-2-methylphenyl)-N-(4-morpholin-4-ylphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine;4-[[5-(3-methylphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]amino]-N-piperidin-4-ylbenzamide is CCN1CCN(c2cccc3nc(Nc4ccnc(C)c4)nn23)CC1.CCc1cc(Nc2nc3cccc(N4CCC(OC)CC4)n3n2)ccn1.CCc1cc(Nc2nc3cccc(N4CCN(CC)CC4)n3n2)ccn1.COc1ccc(-c2cccc3nc(Nc4ccc(N5CCOCC5)cc4)nn23)c(C)c1.Cc1cccc(-c2cccc3nc(Nc4ccc(C(=O)N(C)C)cc4)nn23)c1.Cc1cccc(-c2cccc3nc(Nc4ccc(C(=O)NC5CCNCC5)cc4)nn23)c1.

What is the InChIKey of N,N-dimethyl-4-[[5-(3-methylphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]amino]benzamide;5-(4-ethylpiperazin-1-yl)-N-(2-ethyl-4-pyridinyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine;5-(4-ethylpiperazin-1-yl)-N-(2-methyl-4-pyridinyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine;N-(2-ethyl-4-pyridinyl)-5-(4-methoxypiperidin-1-yl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine;5-(4-methoxy-2-methylphenyl)-N-(4-morpholin-4-ylphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine;4-[[5-(3-methylphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]amino]-N-piperidin-4-ylbenzamide?

The InChIKey is AFJUVQVQNFAAPD-UHFFFAOYSA-N. The full InChI is InChI=1S/C25H26N6O.C24H25N5O2.C22H21N5O.C19H25N7.C19H24N6O.C18H23N7/c1-17-4-2-5-19(16-17)22-6-3-7-23-29-25(30-31(22)23)28-20-10-8-18(9-11-20)24(32)27-21-12-14-26-15-13-21;1-17-16-20(30-2)10-11-21(17)22-4-3-5-23-26-24(27-29(22)23)25-18-6-8-19(9-7-18)28-12-14-31-15-13-28;1-15-6-4-7-17(14-15)19-8-5-9-20-24-22(25-27(19)20)23-18-12-10-16(11-13-18)21(28)26(2)3;1-3-15-14-16(8-9-20-15)21-19-22-17-6-5-7-18(26(17)23-19)25-12-10-24(4-2)11-13-25;1-3-14-13-15(7-10-20-14)21-19-22-17-5-4-6-18(25(17)23-19)24-11-8-16(26-2)9-12-24;1-3-23-9-11-24(12-10-23)17-6-4-5-16-21-18(22-25(16)17)20-15-7-8-19-14(2)13-15/h2-11,16,21,26H,12-15H2,1H3,(H,27,32)(H,28,30);3-11,16H,12-15H2,1-2H3,(H,25,27);4-14H,1-3H3,(H,23,25);5-9,14H,3-4,10-13H2,1-2H3,(H,20,21,23);4-7,10,13,16H,3,8-9,11-12H2,1-2H3,(H,20,21,23);4-8,13H,3,9-12H2,1-2H3,(H,19,20,22).

What are the key properties of N,N-dimethyl-4-[[5-(3-methylphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]amino]benzamide;5-(4-ethylpiperazin-1-yl)-N-(2-ethyl-4-pyridinyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine;5-(4-ethylpiperazin-1-yl)-N-(2-methyl-4-pyridinyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine;N-(2-ethyl-4-pyridinyl)-5-(4-methoxypiperidin-1-yl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine;5-(4-methoxy-2-methylphenyl)-N-(4-morpholin-4-ylphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine;4-[[5-(3-methylphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]amino]-N-piperidin-4-ylbenzamide?

N,N-dimethyl-4-[[5-(3-methylphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]amino]benzamide;5-(4-ethylpiperazin-1-yl)-N-(2-ethyl-4-pyridinyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine;5-(4-ethylpiperazin-1-yl)-N-(2-methyl-4-pyridinyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine;N-(2-ethyl-4-pyridinyl)-5-(4-methoxypiperidin-1-yl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine;5-(4-methoxy-2-methylphenyl)-N-(4-morpholin-4-ylphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine;4-[[5-(3-methylphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]amino]-N-piperidin-4-ylbenzamide has a molecular weight of 2254.80 g/mol, XLogP of 20.31, 28 rotatable bonds, 8 hydrogen bond donors, and 39 hydrogen bond acceptors.

Where does this data come from?

All data for N,N-dimethyl-4-[[5-(3-methylphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]amino]benzamide;5-(4-ethylpiperazin-1-yl)-N-(2-ethyl-4-pyridinyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine;5-(4-ethylpiperazin-1-yl)-N-(2-methyl-4-pyridinyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine;N-(2-ethyl-4-pyridinyl)-5-(4-methoxypiperidin-1-yl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine;5-(4-methoxy-2-methylphenyl)-N-(4-morpholin-4-ylphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine;4-[[5-(3-methylphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]amino]-N-piperidin-4-ylbenzamide is sourced from PubChem (CID 157097610), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).