2-[8-(dimethylamino)-1-(oxetan-3-ylmethyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzamide;8-(dimethylamino)-3-[2-(3-oxopiperazin-1-yl)pyrimidin-5-yl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[8-(ethylamino)-1-[(1-hydroxycyclobutyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzonitrile;4-[8-(ethylamino)-1-[(1-hydroxycyclobutyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-3-methoxybenzonitrile;4-[1-[(1-hydroxycyclobutyl)methyl]-8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-3-methoxybenzonitrile;5-[1-[(1-hydroxycyclobutyl)methyl]-8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-methoxypyrimidine-2-carbonitrile;4-methoxy-5-[8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;2-[8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzamide

C205H251N39O20 — CID 157101867

IUPAC2-[8-(dimethylamino)-1-(oxetan-3-ylmethyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzamide;8-(dimethylamino)-3-[2-(3-oxopiperazin-1-yl)pyrimidin-5-yl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[8-(ethylamino)-1-[(1-hydroxycyclobutyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzonitrile;4-[8-(ethylamino)-1-[(1-hydroxycyclobutyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-3-methoxybenzonitrile;4-[1-[(1-hydroxycyclobutyl)methyl]-8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-3-methoxybenzonitrile;5-[1-[(1-hydroxycyclobutyl)methyl]-8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-methoxypyrimidine-2-carbonitrile;4-methoxy-5-[8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;2-[8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzamide
SMILESCCNC1(c2ccccc2)CCC2(CC1)CN(c1ccc(C#N)cc1OC)C(=O)N2CC1(O)CCC1.CCNC1(c2ccccc2)CCC2(CC1)CN(c1ccccc1C#N)C(=O)N2CC1(O)CCC1.CN(C)C1(c2ccccc2)CCC2(CC1)CN(c1ccccc1C(N)=O)C(=O)N2CC1COC1.CN(C)C1(c2ccccc2)CCC2(CC1)CN(c1cnc(N3CCNC(=O)C3)nc1)C(=O)N2.CNC1(c2ccccc2)CCC2(CC1)CN(c1ccc(C#N)cc1OC)C(=O)N2CC1(O)CCC1.CNC1(c2ccccc2)CCC2(CC1)CN(c1ccccc1C(N)=O)C(=O)N2.CNC1(c2ccccc2)CCC2(CC1)CN(c1cnc(C#N)nc1OC)C(=O)N2.CNC1(c2ccccc2)CCC2(CC1)CN(c1cnc(C#N)nc1OC)C(=O)N2CC1(O)CCC1
InChIInChI=1S/C29H36N4O3.C28H34N4O3.C28H34N4O2.C27H34N4O3.C26H32N6O3.C24H31N7O2.C22H26N4O2.C21H24N6O2/c1-3-31-29(23-8-5-4-6-9-23)16-14-27(15-17-29)20-32(24-11-10-22(19-30)18-25(24)36-2)26(34)33(27)21-28(35)12-7-13-28;1-30-28(22-7-4-3-5-8-22)15-13-26(14-16-28)19-31(23-10-9-21(18-29)17-24(23)35-2)25(33)32(26)20-27(34)11-6-12-27;1-2-30-28(23-10-4-3-5-11-23)17-15-26(16-18-28)20-31(24-12-7-6-9-22(24)19-29)25(33)32(26)21-27(34)13-8-14-27;1-29(2)27(21-8-4-3-5-9-21)14-12-26(13-15-27)19-30(23-11-7-6-10-22(23)24(28)32)25(33)31(26)16-20-17-34-18-20;1-28-26(19-7-4-3-5-8-19)13-11-24(12-14-26)17-31(20-16-29-21(15-27)30-22(20)35-2)23(33)32(24)18-25(34)9-6-10-25;1-29(2)24(18-6-4-3-5-7-18)10-8-23(9-11-24)17-31(22(33)28-23)19-14-26-21(27-15-19)30-13-12-25-20(32)16-30;1-24-22(16-7-3-2-4-8-16)13-11-21(12-14-22)15-26(20(28)25-21)18-10-6-5-9-17(18)19(23)27;1-23-21(15-6-4-3-5-7-15)10-8-20(9-11-21)14-27(19(28)26-20)16-13-24-17(12-22)25-18(16)29-2/h4-6,8-11,18,31,35H,3,7,12-17,20-21H2,1-2H3;3-5,7-10,17,30,34H,6,11-16,19-20H2,1-2H3;3-7,9-12,30,34H,2,8,13-18,20-21H2,1H3;3-11,20H,12-19H2,1-2H3,(H2,28,32);3-5,7-8,16,28,34H,6,9-14,17-18H2,1-2H3;3-7,14-15H,8-13,16-17H2,1-2H3,(H,25,32)(H,28,33);2-10,24H,11-15H2,1H3,(H2,23,27)(H,25,28);3-7,13,23H,8-11,14H2,1-2H3,(H,26,28)
InChIKeyAFVWAGKTXHGSNK-UHFFFAOYSA-N
MW3581.52 g/mol
LogP26.38
Rot. Bonds43

About 2-[8-(dimethylamino)-1-(oxetan-3-ylmethyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzamide;8-(dimethylamino)-3-[2-(3-oxopiperazin-1-yl)pyrimidin-5-yl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[8-(ethylamino)-1-[(1-hydroxycyclobutyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzonitrile;4-[8-(ethylamino)-1-[(1-hydroxycyclobutyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-3-methoxybenzonitrile;4-[1-[(1-hydroxycyclobutyl)methyl]-8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-3-methoxybenzonitrile;5-[1-[(1-hydroxycyclobutyl)methyl]-8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-methoxypyrimidine-2-carbonitrile;4-methoxy-5-[8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;2-[8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzamide

2-[8-(dimethylamino)-1-(oxetan-3-ylmethyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzamide;8-(dimethylamino)-3-[2-(3-oxopiperazin-1-yl)pyrimidin-5-yl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[8-(ethylamino)-1-[(1-hydroxycyclobutyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzonitrile;4-[8-(ethylamino)-1-[(1-hydroxycyclobutyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-3-methoxybenzonitrile;4-[1-[(1-hydroxycyclobutyl)methyl]-8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-3-methoxybenzonitrile;5-[1-[(1-hydroxycyclobutyl)methyl]-8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-methoxypyrimidine-2-carbonitrile;4-methoxy-5-[8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;2-[8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzamide (PubChem CID 157101867) has the molecular formula C205H251N39O20 and a molecular weight of 3581.52 g/mol. Its IUPAC name is 2-[8-(dimethylamino)-1-(oxetan-3-ylmethyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzamide;8-(dimethylamino)-3-[2-(3-oxopiperazin-1-yl)pyrimidin-5-yl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[8-(ethylamino)-1-[(1-hydroxycyclobutyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzonitrile;4-[8-(ethylamino)-1-[(1-hydroxycyclobutyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-3-methoxybenzonitrile;4-[1-[(1-hydroxycyclobutyl)methyl]-8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-3-methoxybenzonitrile;5-[1-[(1-hydroxycyclobutyl)methyl]-8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-methoxypyrimidine-2-carbonitrile;4-methoxy-5-[8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;2-[8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzamide.

Molecular Properties

Compound Name2-[8-(dimethylamino)-1-(oxetan-3-ylmethyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzamide;8-(dimethylamino)-3-[2-(3-oxopiperazin-1-yl)pyrimidin-5-yl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[8-(ethylamino)-1-[(1-hydroxycyclobutyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzonitrile;4-[8-(ethylamino)-1-[(1-hydroxycyclobutyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-3-methoxybenzonitrile;4-[1-[(1-hydroxycyclobutyl)methyl]-8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-3-methoxybenzonitrile;5-[1-[(1-hydroxycyclobutyl)methyl]-8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-methoxypyrimidine-2-carbonitrile;4-methoxy-5-[8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;2-[8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzamide
PubChem CID157101867
Molecular FormulaC205H251N39O20
Molecular Weight3581.52 g/mol
Exact Mass3578.98
IUPAC Name2-[8-(dimethylamino)-1-(oxetan-3-ylmethyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzamide;8-(dimethylamino)-3-[2-(3-oxopiperazin-1-yl)pyrimidin-5-yl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[8-(ethylamino)-1-[(1-hydroxycyclobutyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzonitrile;4-[8-(ethylamino)-1-[(1-hydroxycyclobutyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-3-methoxybenzonitrile;4-[1-[(1-hydroxycyclobutyl)methyl]-8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-3-methoxybenzonitrile;5-[1-[(1-hydroxycyclobutyl)methyl]-8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-methoxypyrimidine-2-carbonitrile;4-methoxy-5-[8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;2-[8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzamide
SMILESCCNC1(c2ccccc2)CCC2(CC1)CN(c1ccc(C#N)cc1OC)C(=O)N2CC1(O)CCC1.CCNC1(c2ccccc2)CCC2(CC1)CN(c1ccccc1C#N)C(=O)N2CC1(O)CCC1.CN(C)C1(c2ccccc2)CCC2(CC1)CN(c1ccccc1C(N)=O)C(=O)N2CC1COC1.CN(C)C1(c2ccccc2)CCC2(CC1)CN(c1cnc(N3CCNC(=O)C3)nc1)C(=O)N2.CNC1(c2ccccc2)CCC2(CC1)CN(c1ccc(C#N)cc1OC)C(=O)N2CC1(O)CCC1.CNC1(c2ccccc2)CCC2(CC1)CN(c1ccccc1C(N)=O)C(=O)N2.CNC1(c2ccccc2)CCC2(CC1)CN(c1cnc(C#N)nc1OC)C(=O)N2.CNC1(c2ccccc2)CCC2(CC1)CN(c1cnc(C#N)nc1OC)C(=O)N2CC1(O)CCC1
InChIInChI=1S/C29H36N4O3.C28H34N4O3.C28H34N4O2.C27H34N4O3.C26H32N6O3.C24H31N7O2.C22H26N4O2.C21H24N6O2/c1-3-31-29(23-8-5-4-6-9-23)16-14-27(15-17-29)20-32(24-11-10-22(19-30)18-25(24)36-2)26(34)33(27)21-28(35)12-7-13-28;1-30-28(22-7-4-3-5-8-22)15-13-26(14-16-28)19-31(23-10-9-21(18-29)17-24(23)35-2)25(33)32(26)20-27(34)11-6-12-27;1-2-30-28(23-10-4-3-5-11-23)17-15-26(16-18-28)20-31(24-12-7-6-9-22(24)19-29)25(33)32(26)21-27(34)13-8-14-27;1-29(2)27(21-8-4-3-5-9-21)14-12-26(13-15-27)19-30(23-11-7-6-10-22(23)24(28)32)25(33)31(26)16-20-17-34-18-20;1-28-26(19-7-4-3-5-8-19)13-11-24(12-14-26)17-31(20-16-29-21(15-27)30-22(20)35-2)23(33)32(24)18-25(34)9-6-10-25;1-29(2)24(18-6-4-3-5-7-18)10-8-23(9-11-24)17-31(22(33)28-23)19-14-26-21(27-15-19)30-13-12-25-20(32)16-30;1-24-22(16-7-3-2-4-8-16)13-11-21(12-14-22)15-26(20(28)25-21)18-10-6-5-9-17(18)19(23)27;1-23-21(15-6-4-3-5-7-15)10-8-20(9-11-21)14-27(19(28)26-20)16-13-24-17(12-22)25-18(16)29-2/h4-6,8-11,18,31,35H,3,7,12-17,20-21H2,1-2H3;3-5,7-10,17,30,34H,6,11-16,19-20H2,1-2H3;3-7,9-12,30,34H,2,8,13-18,20-21H2,1H3;3-11,20H,12-19H2,1-2H3,(H2,28,32);3-5,7-8,16,28,34H,6,9-14,17-18H2,1-2H3;3-7,14-15H,8-13,16-17H2,1-2H3,(H,25,32)(H,28,33);2-10,24H,11-15H2,1H3,(H2,23,27)(H,25,28);3-7,13,23H,8-11,14H2,1-2H3,(H,26,28)
InChIKeyAFVWAGKTXHGSNK-UHFFFAOYSA-N
XLogP26.38
TPSA735.31 Ų
H-Bond Donors16
H-Bond Acceptors40
Rotatable Bonds43
Heavy Atoms264
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5003581.52
LogP ≤ 526.38
H-Bond Donors ≤ 516
H-Bond Acceptors ≤ 1040

Analyze 2-[8-(dimethylamino)-1-(oxetan-3-ylmethyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzamide;8-(dimethylamino)-3-[2-(3-oxopiperazin-1-yl)pyrimidin-5-yl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[8-(ethylamino)-1-[(1-hydroxycyclobutyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzonitrile;4-[8-(ethylamino)-1-[(1-hydroxycyclobutyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-3-methoxybenzonitrile;4-[1-[(1-hydroxycyclobutyl)methyl]-8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-3-methoxybenzonitrile;5-[1-[(1-hydroxycyclobutyl)methyl]-8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-methoxypyrimidine-2-carbonitrile;4-methoxy-5-[8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;2-[8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzamide with MolForge

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Related Compounds

3-[2-(4-Acetylpiperazin-1-yl)pyrimidin-5-yl]-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-[cyclopropylmethyl(methyl)amino]-8-phenyl-3-[2-(trifluoromethyl)pyrimidin-5-yl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-[2-(4-methylpiperazine-1-carbonyl)pyrimidin-5-yl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;bis(4-[8-(ethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-3-methoxybenzonitrile)
CID 157523081
3-[2-(4-Acetylpiperazin-1-yl)pyrimidin-5-yl]-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-[cyclopropylmethyl(methyl)amino]-8-phenyl-3-[2-(trifluoromethyl)pyrimidin-5-yl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-[2-(4-methylpiperazine-1-carbonyl)pyrimidin-5-yl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-[2-(4-methylsulfonylpiperazin-1-yl)pyrimidin-5-yl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-[5-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidin-2-yl]benzamide;3-[5-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidin-2-yl]benzonitrile;bis(4-[8-(ethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-3-methoxybenzonitrile)
CID 157668261
CID 157935129
CID 157935129
3-[2-(4-acetylpiperazin-1-yl)pyrimidin-5-yl]-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-[cyclopropylmethyl(methyl)amino]-8-phenyl-3-[2-(trifluoromethyl)pyrimidin-5-yl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-[2-(4-methylpiperazine-1-carbonyl)pyrimidin-5-yl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;5-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-(2-hydroxyethyl)pyrimidine-2-carboxamide;5-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carboxamide;3-[5-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidin-2-yl]benzamide;8-(dimethylamino)-8-phenyl-3-(2-pyridin-3-ylpyrimidin-5-yl)-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-(2-pyridin-4-ylpyrimidin-5-yl)-1,3-diazaspiro[4.5]decan-2-one;bis(4-[8-(ethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-3-methoxybenzonitrile)
CID 158756260
CID 158940407
CID 158940407
CID 157084308
CID 157084308
2-[8-(Dimethylamino)-1-(oxetan-3-ylmethyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzamide;8-(dimethylamino)-3-[2-(3-oxopiperazin-1-yl)pyrimidin-5-yl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;4-methoxy-5-[8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;2-[8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzamide
CID 157504698
2-[8-(Ethylamino)-1-[(1-hydroxycyclobutyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzonitrile;4-[8-(ethylamino)-1-[(1-hydroxycyclobutyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-3-methoxybenzonitrile;2-[1-[(1-hydroxycyclobutyl)methyl]-8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzonitrile;4-[1-[(1-hydroxycyclobutyl)methyl]-8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-3-methoxybenzonitrile;5-[1-[(1-hydroxycyclobutyl)methyl]-8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-methoxypyrimidine-2-carbonitrile
CID 157575884
5-[1-(Cyclobutylmethyl)-8-[ethyl(methyl)amino]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-methoxypyrimidine-2-carbonitrile;4-[1-(cyclobutylmethyl)-8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-3-methoxybenzonitrile;5-[8-(dimethylamino)-1-(3-methoxypropyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-6-methoxypyridine-2-carbonitrile;5-[8-(dimethylamino)-2-oxo-1-(2-oxohexyl)-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile
CID 157605366
CID 157855339
CID 157855339
CID 157859411
CID 157859411
2-[1-(Cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzamide;3-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzamide;5-[8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carboxamide;5-[1-[(1-hydroxycyclobutyl)methyl]-8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-methoxypyrimidine-2-carbonitrile
CID 158407392

Frequently Asked Questions

What is the IUPAC name of 2-[8-(dimethylamino)-1-(oxetan-3-ylmethyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzamide;8-(dimethylamino)-3-[2-(3-oxopiperazin-1-yl)pyrimidin-5-yl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[8-(ethylamino)-1-[(1-hydroxycyclobutyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzonitrile;4-[8-(ethylamino)-1-[(1-hydroxycyclobutyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-3-methoxybenzonitrile;4-[1-[(1-hydroxycyclobutyl)methyl]-8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-3-methoxybenzonitrile;5-[1-[(1-hydroxycyclobutyl)methyl]-8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-methoxypyrimidine-2-carbonitrile;4-methoxy-5-[8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;2-[8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzamide?
The IUPAC name of 2-[8-(dimethylamino)-1-(oxetan-3-ylmethyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzamide;8-(dimethylamino)-3-[2-(3-oxopiperazin-1-yl)pyrimidin-5-yl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[8-(ethylamino)-1-[(1-hydroxycyclobutyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzonitrile;4-[8-(ethylamino)-1-[(1-hydroxycyclobutyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-3-methoxybenzonitrile;4-[1-[(1-hydroxycyclobutyl)methyl]-8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-3-methoxybenzonitrile;5-[1-[(1-hydroxycyclobutyl)methyl]-8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-methoxypyrimidine-2-carbonitrile;4-methoxy-5-[8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;2-[8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzamide (CID 157101867) is 2-[8-(dimethylamino)-1-(oxetan-3-ylmethyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzamide;8-(dimethylamino)-3-[2-(3-oxopiperazin-1-yl)pyrimidin-5-yl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[8-(ethylamino)-1-[(1-hydroxycyclobutyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzonitrile;4-[8-(ethylamino)-1-[(1-hydroxycyclobutyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-3-methoxybenzonitrile;4-[1-[(1-hydroxycyclobutyl)methyl]-8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-3-methoxybenzonitrile;5-[1-[(1-hydroxycyclobutyl)methyl]-8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-methoxypyrimidine-2-carbonitrile;4-methoxy-5-[8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;2-[8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzamide.
What is the SMILES notation for 2-[8-(dimethylamino)-1-(oxetan-3-ylmethyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzamide;8-(dimethylamino)-3-[2-(3-oxopiperazin-1-yl)pyrimidin-5-yl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[8-(ethylamino)-1-[(1-hydroxycyclobutyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzonitrile;4-[8-(ethylamino)-1-[(1-hydroxycyclobutyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-3-methoxybenzonitrile;4-[1-[(1-hydroxycyclobutyl)methyl]-8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-3-methoxybenzonitrile;5-[1-[(1-hydroxycyclobutyl)methyl]-8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-methoxypyrimidine-2-carbonitrile;4-methoxy-5-[8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;2-[8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzamide?
The canonical SMILES for 2-[8-(dimethylamino)-1-(oxetan-3-ylmethyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzamide;8-(dimethylamino)-3-[2-(3-oxopiperazin-1-yl)pyrimidin-5-yl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[8-(ethylamino)-1-[(1-hydroxycyclobutyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzonitrile;4-[8-(ethylamino)-1-[(1-hydroxycyclobutyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-3-methoxybenzonitrile;4-[1-[(1-hydroxycyclobutyl)methyl]-8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-3-methoxybenzonitrile;5-[1-[(1-hydroxycyclobutyl)methyl]-8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-methoxypyrimidine-2-carbonitrile;4-methoxy-5-[8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;2-[8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzamide is CCNC1(c2ccccc2)CCC2(CC1)CN(c1ccc(C#N)cc1OC)C(=O)N2CC1(O)CCC1.CCNC1(c2ccccc2)CCC2(CC1)CN(c1ccccc1C#N)C(=O)N2CC1(O)CCC1.CN(C)C1(c2ccccc2)CCC2(CC1)CN(c1ccccc1C(N)=O)C(=O)N2CC1COC1.CN(C)C1(c2ccccc2)CCC2(CC1)CN(c1cnc(N3CCNC(=O)C3)nc1)C(=O)N2.CNC1(c2ccccc2)CCC2(CC1)CN(c1ccc(C#N)cc1OC)C(=O)N2CC1(O)CCC1.CNC1(c2ccccc2)CCC2(CC1)CN(c1ccccc1C(N)=O)C(=O)N2.CNC1(c2ccccc2)CCC2(CC1)CN(c1cnc(C#N)nc1OC)C(=O)N2.CNC1(c2ccccc2)CCC2(CC1)CN(c1cnc(C#N)nc1OC)C(=O)N2CC1(O)CCC1.
What is the InChIKey of 2-[8-(dimethylamino)-1-(oxetan-3-ylmethyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzamide;8-(dimethylamino)-3-[2-(3-oxopiperazin-1-yl)pyrimidin-5-yl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[8-(ethylamino)-1-[(1-hydroxycyclobutyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzonitrile;4-[8-(ethylamino)-1-[(1-hydroxycyclobutyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-3-methoxybenzonitrile;4-[1-[(1-hydroxycyclobutyl)methyl]-8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-3-methoxybenzonitrile;5-[1-[(1-hydroxycyclobutyl)methyl]-8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-methoxypyrimidine-2-carbonitrile;4-methoxy-5-[8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;2-[8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzamide?
The InChIKey is AFVWAGKTXHGSNK-UHFFFAOYSA-N. The full InChI is InChI=1S/C29H36N4O3.C28H34N4O3.C28H34N4O2.C27H34N4O3.C26H32N6O3.C24H31N7O2.C22H26N4O2.C21H24N6O2/c1-3-31-29(23-8-5-4-6-9-23)16-14-27(15-17-29)20-32(24-11-10-22(19-30)18-25(24)36-2)26(34)33(27)21-28(35)12-7-13-28;1-30-28(22-7-4-3-5-8-22)15-13-26(14-16-28)19-31(23-10-9-21(18-29)17-24(23)35-2)25(33)32(26)20-27(34)11-6-12-27;1-2-30-28(23-10-4-3-5-11-23)17-15-26(16-18-28)20-31(24-12-7-6-9-22(24)19-29)25(33)32(26)21-27(34)13-8-14-27;1-29(2)27(21-8-4-3-5-9-21)14-12-26(13-15-27)19-30(23-11-7-6-10-22(23)24(28)32)25(33)31(26)16-20-17-34-18-20;1-28-26(19-7-4-3-5-8-19)13-11-24(12-14-26)17-31(20-16-29-21(15-27)30-22(20)35-2)23(33)32(24)18-25(34)9-6-10-25;1-29(2)24(18-6-4-3-5-7-18)10-8-23(9-11-24)17-31(22(33)28-23)19-14-26-21(27-15-19)30-13-12-25-20(32)16-30;1-24-22(16-7-3-2-4-8-16)13-11-21(12-14-22)15-26(20(28)25-21)18-10-6-5-9-17(18)19(23)27;1-23-21(15-6-4-3-5-7-15)10-8-20(9-11-21)14-27(19(28)26-20)16-13-24-17(12-22)25-18(16)29-2/h4-6,8-11,18,31,35H,3,7,12-17,20-21H2,1-2H3;3-5,7-10,17,30,34H,6,11-16,19-20H2,1-2H3;3-7,9-12,30,34H,2,8,13-18,20-21H2,1H3;3-11,20H,12-19H2,1-2H3,(H2,28,32);3-5,7-8,16,28,34H,6,9-14,17-18H2,1-2H3;3-7,14-15H,8-13,16-17H2,1-2H3,(H,25,32)(H,28,33);2-10,24H,11-15H2,1H3,(H2,23,27)(H,25,28);3-7,13,23H,8-11,14H2,1-2H3,(H,26,28).
What are the key properties of 2-[8-(dimethylamino)-1-(oxetan-3-ylmethyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzamide;8-(dimethylamino)-3-[2-(3-oxopiperazin-1-yl)pyrimidin-5-yl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[8-(ethylamino)-1-[(1-hydroxycyclobutyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzonitrile;4-[8-(ethylamino)-1-[(1-hydroxycyclobutyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-3-methoxybenzonitrile;4-[1-[(1-hydroxycyclobutyl)methyl]-8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-3-methoxybenzonitrile;5-[1-[(1-hydroxycyclobutyl)methyl]-8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-methoxypyrimidine-2-carbonitrile;4-methoxy-5-[8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;2-[8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzamide?
2-[8-(dimethylamino)-1-(oxetan-3-ylmethyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzamide;8-(dimethylamino)-3-[2-(3-oxopiperazin-1-yl)pyrimidin-5-yl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[8-(ethylamino)-1-[(1-hydroxycyclobutyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzonitrile;4-[8-(ethylamino)-1-[(1-hydroxycyclobutyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-3-methoxybenzonitrile;4-[1-[(1-hydroxycyclobutyl)methyl]-8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-3-methoxybenzonitrile;5-[1-[(1-hydroxycyclobutyl)methyl]-8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-methoxypyrimidine-2-carbonitrile;4-methoxy-5-[8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;2-[8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzamide has a molecular weight of 3581.52 g/mol, XLogP of 26.38, 43 rotatable bonds, 16 hydrogen bond donors, and 40 hydrogen bond acceptors.
Where does this data come from?
All data for 2-[8-(dimethylamino)-1-(oxetan-3-ylmethyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzamide;8-(dimethylamino)-3-[2-(3-oxopiperazin-1-yl)pyrimidin-5-yl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[8-(ethylamino)-1-[(1-hydroxycyclobutyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzonitrile;4-[8-(ethylamino)-1-[(1-hydroxycyclobutyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-3-methoxybenzonitrile;4-[1-[(1-hydroxycyclobutyl)methyl]-8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-3-methoxybenzonitrile;5-[1-[(1-hydroxycyclobutyl)methyl]-8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-methoxypyrimidine-2-carbonitrile;4-methoxy-5-[8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;2-[8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzamide is sourced from PubChem (CID 157101867), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).