N-tert-butylsulfonyl-5-[(2R,4S)-4-fluoro-2-[5-fluoro-2-(oxolan-3-yloxy)phenyl]pyrrolidin-1-yl]pyrazolo[1,5-a]pyridine-3-carboxamide;5-[(2R,4S)-2-[2-(cyclopropylmethoxy)-5-fluorophenyl]-4-fluoropyrrolidin-1-yl]-N-[ethyl(methyl)sulfamoyl]pyrazolo[1,5-a]pyridine-3-carboxamide;5-[(2R,4S)-2-[3-(cyclopropylmethoxy)-5-fluorophenyl]-4-fluoropyrrolidin-1-yl]-N-[ethyl(methyl)sulfamoyl]pyrazolo[1,5-a]pyridine-3-carboxamide;N-[ethyl(methyl)sulfamoyl]-5-[(2R,4S)-4-fluoro-2-[5-fluoro-2-(oxolan-3-yloxy)phenyl]pyrrolidin-1-yl]pyrazolo[1,5-a]pyridine-3-carboxamide

C101H117F8N19O18S4 — CID 157102152

About N-tert-butylsulfonyl-5-[(2R,4S)-4-fluoro-2-[5-fluoro-2-(oxolan-3-yloxy)phenyl]pyrrolidin-1-yl]pyrazolo[1,5-a]pyridine-3-carboxamide;5-[(2R,4S)-2-[2-(cyclopropylmethoxy)-5-fluorophenyl]-4-fluoropyrrolidin-1-yl]-N-[ethyl(methyl)sulfamoyl]pyrazolo[1,5-a]pyridine-3-carboxamide;5-[(2R,4S)-2-[3-(cyclopropylmethoxy)-5-fluorophenyl]-4-fluoropyrrolidin-1-yl]-N-[ethyl(methyl)sulfamoyl]pyrazolo[1,5-a]pyridine-3-carboxamide;N-[ethyl(methyl)sulfamoyl]-5-[(2R,4S)-4-fluoro-2-[5-fluoro-2-(oxolan-3-yloxy)phenyl]pyrrolidin-1-yl]pyrazolo[1,5-a]pyridine-3-carboxamide

N-tert-butylsulfonyl-5-[(2R,4S)-4-fluoro-2-[5-fluoro-2-(oxolan-3-yloxy)phenyl]pyrrolidin-1-yl]pyrazolo[1,5-a]pyridine-3-carboxamide;5-[(2R,4S)-2-[2-(cyclopropylmethoxy)-5-fluorophenyl]-4-fluoropyrrolidin-1-yl]-N-[ethyl(methyl)sulfamoyl]pyrazolo[1,5-a]pyridine-3-carboxamide;5-[(2R,4S)-2-[3-(cyclopropylmethoxy)-5-fluorophenyl]-4-fluoropyrrolidin-1-yl]-N-[ethyl(methyl)sulfamoyl]pyrazolo[1,5-a]pyridine-3-carboxamide;N-[ethyl(methyl)sulfamoyl]-5-[(2R,4S)-4-fluoro-2-[5-fluoro-2-(oxolan-3-yloxy)phenyl]pyrrolidin-1-yl]pyrazolo[1,5-a]pyridine-3-carboxamide (PubChem CID 157102152) has the molecular formula C101H117F8N19O18S4 and a molecular weight of 2165.41 g/mol. Its IUPAC name is N-tert-butylsulfonyl-5-[(2R,4S)-4-fluoro-2-[5-fluoro-2-(oxolan-3-yloxy)phenyl]pyrrolidin-1-yl]pyrazolo[1,5-a]pyridine-3-carboxamide;5-[(2R,4S)-2-[2-(cyclopropylmethoxy)-5-fluorophenyl]-4-fluoropyrrolidin-1-yl]-N-[ethyl(methyl)sulfamoyl]pyrazolo[1,5-a]pyridine-3-carboxamide;5-[(2R,4S)-2-[3-(cyclopropylmethoxy)-5-fluorophenyl]-4-fluoropyrrolidin-1-yl]-N-[ethyl(methyl)sulfamoyl]pyrazolo[1,5-a]pyridine-3-carboxamide;N-[ethyl(methyl)sulfamoyl]-5-[(2R,4S)-4-fluoro-2-[5-fluoro-2-(oxolan-3-yloxy)phenyl]pyrrolidin-1-yl]pyrazolo[1,5-a]pyridine-3-carboxamide.

Molecular Properties

• Compound Name: N-tert-butylsulfonyl-5-[(2R,4S)-4-fluoro-2-[5-fluoro-2-(oxolan-3-yloxy)phenyl]pyrrolidin-1-yl]pyrazolo[1,5-a]pyridine-3-carboxamide;5-[(2R,4S)-2-[2-(cyclopropylmethoxy)-5-fluorophenyl]-4-fluoropyrrolidin-1-yl]-N-[ethyl(methyl)sulfamoyl]pyrazolo[1,5-a]pyridine-3-carboxamide;5-[(2R,4S)-2-[3-(cyclopropylmethoxy)-5-fluorophenyl]-4-fluoropyrrolidin-1-yl]-N-[ethyl(methyl)sulfamoyl]pyrazolo[1,5-a]pyridine-3-carboxamide;N-[ethyl(methyl)sulfamoyl]-5-[(2R,4S)-4-fluoro-2-[5-fluoro-2-(oxolan-3-yloxy)phenyl]pyrrolidin-1-yl]pyrazolo[1,5-a]pyridine-3-carboxamide
• PubChem CID: 157102152
• Molecular Formula: C101H117F8N19O18S4
• Molecular Weight: 2165.41 g/mol
• Exact Mass: 2163.76
• IUPAC Name: N-tert-butylsulfonyl-5-[(2R,4S)-4-fluoro-2-[5-fluoro-2-(oxolan-3-yloxy)phenyl]pyrrolidin-1-yl]pyrazolo[1,5-a]pyridine-3-carboxamide;5-[(2R,4S)-2-[2-(cyclopropylmethoxy)-5-fluorophenyl]-4-fluoropyrrolidin-1-yl]-N-[ethyl(methyl)sulfamoyl]pyrazolo[1,5-a]pyridine-3-carboxamide;5-[(2R,4S)-2-[3-(cyclopropylmethoxy)-5-fluorophenyl]-4-fluoropyrrolidin-1-yl]-N-[ethyl(methyl)sulfamoyl]pyrazolo[1,5-a]pyridine-3-carboxamide;N-[ethyl(methyl)sulfamoyl]-5-[(2R,4S)-4-fluoro-2-[5-fluoro-2-(oxolan-3-yloxy)phenyl]pyrrolidin-1-yl]pyrazolo[1,5-a]pyridine-3-carboxamide
• SMILES: CC(C)(C)S(=O)(=O)NC(=O)c1cnn2ccc(N3C[C@@H](F)C[C@@H]3c3cc(F)ccc3OC3CCOC3)cc12.CCN(C)S(=O)(=O)NC(=O)c1cnn2ccc(N3C[C@@H](F)C[C@@H]3c3cc(F)cc(OCC4CC4)c3)cc12.CCN(C)S(=O)(=O)NC(=O)c1cnn2ccc(N3C[C@@H](F)C[C@@H]3c3cc(F)ccc3OC3CCOC3)cc12.CCN(C)S(=O)(=O)NC(=O)c1cnn2ccc(N3C[C@@H](F)C[C@@H]3c3cc(F)ccc3OCC3CC3)cc12
• InChI: InChI=1S/C26H30F2N4O5S.C25H29F2N5O5S.2C25H29F2N5O4S/c1-26(2,3)38(34,35)30-25(33)21-13-29-32-8-6-18(12-23(21)32)31-14-17(28)11-22(31)20-10-16(27)4-5-24(20)37-19-7-9-36-15-19;1-3-30(2)38(34,35)29-25(33)21-13-28-32-8-6-18(12-23(21)32)31-14-17(27)11-22(31)20-10-16(26)4-5-24(20)37-19-7-9-36-15-19;1-3-30(2)37(34,35)29-25(33)22-13-28-32-7-6-20(12-24(22)32)31-14-19(27)11-23(31)17-8-18(26)10-21(9-17)36-15-16-4-5-16;1-3-30(2)37(34,35)29-25(33)21-13-28-32-9-8-19(12-23(21)32)31-14-18(27)11-22(31)20-10-17(26)6-7-24(20)36-15-16-4-5-16/h4-6,8,10,12-13,17,19,22H,7,9,11,14-15H2,1-3H3,(H,30,33);4-6,8,10,12-13,17,19,22H,3,7,9,11,14-15H2,1-2H3,(H,29,33);6-10,12-13,16,19,23H,3-5,11,14-15H2,1-2H3,(H,29,33);6-10,12-13,16,18,22H,3-5,11,14-15H2,1-2H3,(H,29,33)/t2*17-,19?,22+;19-,23+;18-,22+/m0000/s1
• InChIKey: AFWSELPFZSDRKU-POYNPJPDSA-N
• XLogP: 13.60
• TPSA: 400.22 Ų
• H-Bond Donors: 4
• H-Bond Acceptors: 30
• Rotatable Bonds: 32
• Heavy Atoms: 150
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	2165.41
LogP ≤ 5	13.60
H-Bond Donors ≤ 5	4
H-Bond Acceptors ≤ 10	30

Frequently Asked Questions

What is the IUPAC name of N-tert-butylsulfonyl-5-[(2R,4S)-4-fluoro-2-[5-fluoro-2-(oxolan-3-yloxy)phenyl]pyrrolidin-1-yl]pyrazolo[1,5-a]pyridine-3-carboxamide;5-[(2R,4S)-2-[2-(cyclopropylmethoxy)-5-fluorophenyl]-4-fluoropyrrolidin-1-yl]-N-[ethyl(methyl)sulfamoyl]pyrazolo[1,5-a]pyridine-3-carboxamide;5-[(2R,4S)-2-[3-(cyclopropylmethoxy)-5-fluorophenyl]-4-fluoropyrrolidin-1-yl]-N-[ethyl(methyl)sulfamoyl]pyrazolo[1,5-a]pyridine-3-carboxamide;N-[ethyl(methyl)sulfamoyl]-5-[(2R,4S)-4-fluoro-2-[5-fluoro-2-(oxolan-3-yloxy)phenyl]pyrrolidin-1-yl]pyrazolo[1,5-a]pyridine-3-carboxamide?

The IUPAC name of N-tert-butylsulfonyl-5-[(2R,4S)-4-fluoro-2-[5-fluoro-2-(oxolan-3-yloxy)phenyl]pyrrolidin-1-yl]pyrazolo[1,5-a]pyridine-3-carboxamide;5-[(2R,4S)-2-[2-(cyclopropylmethoxy)-5-fluorophenyl]-4-fluoropyrrolidin-1-yl]-N-[ethyl(methyl)sulfamoyl]pyrazolo[1,5-a]pyridine-3-carboxamide;5-[(2R,4S)-2-[3-(cyclopropylmethoxy)-5-fluorophenyl]-4-fluoropyrrolidin-1-yl]-N-[ethyl(methyl)sulfamoyl]pyrazolo[1,5-a]pyridine-3-carboxamide;N-[ethyl(methyl)sulfamoyl]-5-[(2R,4S)-4-fluoro-2-[5-fluoro-2-(oxolan-3-yloxy)phenyl]pyrrolidin-1-yl]pyrazolo[1,5-a]pyridine-3-carboxamide (CID 157102152) is N-tert-butylsulfonyl-5-[(2R,4S)-4-fluoro-2-[5-fluoro-2-(oxolan-3-yloxy)phenyl]pyrrolidin-1-yl]pyrazolo[1,5-a]pyridine-3-carboxamide;5-[(2R,4S)-2-[2-(cyclopropylmethoxy)-5-fluorophenyl]-4-fluoropyrrolidin-1-yl]-N-[ethyl(methyl)sulfamoyl]pyrazolo[1,5-a]pyridine-3-carboxamide;5-[(2R,4S)-2-[3-(cyclopropylmethoxy)-5-fluorophenyl]-4-fluoropyrrolidin-1-yl]-N-[ethyl(methyl)sulfamoyl]pyrazolo[1,5-a]pyridine-3-carboxamide;N-[ethyl(methyl)sulfamoyl]-5-[(2R,4S)-4-fluoro-2-[5-fluoro-2-(oxolan-3-yloxy)phenyl]pyrrolidin-1-yl]pyrazolo[1,5-a]pyridine-3-carboxamide.

What is the SMILES notation for N-tert-butylsulfonyl-5-[(2R,4S)-4-fluoro-2-[5-fluoro-2-(oxolan-3-yloxy)phenyl]pyrrolidin-1-yl]pyrazolo[1,5-a]pyridine-3-carboxamide;5-[(2R,4S)-2-[2-(cyclopropylmethoxy)-5-fluorophenyl]-4-fluoropyrrolidin-1-yl]-N-[ethyl(methyl)sulfamoyl]pyrazolo[1,5-a]pyridine-3-carboxamide;5-[(2R,4S)-2-[3-(cyclopropylmethoxy)-5-fluorophenyl]-4-fluoropyrrolidin-1-yl]-N-[ethyl(methyl)sulfamoyl]pyrazolo[1,5-a]pyridine-3-carboxamide;N-[ethyl(methyl)sulfamoyl]-5-[(2R,4S)-4-fluoro-2-[5-fluoro-2-(oxolan-3-yloxy)phenyl]pyrrolidin-1-yl]pyrazolo[1,5-a]pyridine-3-carboxamide?

The canonical SMILES for N-tert-butylsulfonyl-5-[(2R,4S)-4-fluoro-2-[5-fluoro-2-(oxolan-3-yloxy)phenyl]pyrrolidin-1-yl]pyrazolo[1,5-a]pyridine-3-carboxamide;5-[(2R,4S)-2-[2-(cyclopropylmethoxy)-5-fluorophenyl]-4-fluoropyrrolidin-1-yl]-N-[ethyl(methyl)sulfamoyl]pyrazolo[1,5-a]pyridine-3-carboxamide;5-[(2R,4S)-2-[3-(cyclopropylmethoxy)-5-fluorophenyl]-4-fluoropyrrolidin-1-yl]-N-[ethyl(methyl)sulfamoyl]pyrazolo[1,5-a]pyridine-3-carboxamide;N-[ethyl(methyl)sulfamoyl]-5-[(2R,4S)-4-fluoro-2-[5-fluoro-2-(oxolan-3-yloxy)phenyl]pyrrolidin-1-yl]pyrazolo[1,5-a]pyridine-3-carboxamide is CC(C)(C)S(=O)(=O)NC(=O)c1cnn2ccc(N3C[C@@H](F)C[C@@H]3c3cc(F)ccc3OC3CCOC3)cc12.CCN(C)S(=O)(=O)NC(=O)c1cnn2ccc(N3C[C@@H](F)C[C@@H]3c3cc(F)cc(OCC4CC4)c3)cc12.CCN(C)S(=O)(=O)NC(=O)c1cnn2ccc(N3C[C@@H](F)C[C@@H]3c3cc(F)ccc3OC3CCOC3)cc12.CCN(C)S(=O)(=O)NC(=O)c1cnn2ccc(N3C[C@@H](F)C[C@@H]3c3cc(F)ccc3OCC3CC3)cc12.

What is the InChIKey of N-tert-butylsulfonyl-5-[(2R,4S)-4-fluoro-2-[5-fluoro-2-(oxolan-3-yloxy)phenyl]pyrrolidin-1-yl]pyrazolo[1,5-a]pyridine-3-carboxamide;5-[(2R,4S)-2-[2-(cyclopropylmethoxy)-5-fluorophenyl]-4-fluoropyrrolidin-1-yl]-N-[ethyl(methyl)sulfamoyl]pyrazolo[1,5-a]pyridine-3-carboxamide;5-[(2R,4S)-2-[3-(cyclopropylmethoxy)-5-fluorophenyl]-4-fluoropyrrolidin-1-yl]-N-[ethyl(methyl)sulfamoyl]pyrazolo[1,5-a]pyridine-3-carboxamide;N-[ethyl(methyl)sulfamoyl]-5-[(2R,4S)-4-fluoro-2-[5-fluoro-2-(oxolan-3-yloxy)phenyl]pyrrolidin-1-yl]pyrazolo[1,5-a]pyridine-3-carboxamide?

The InChIKey is AFWSELPFZSDRKU-POYNPJPDSA-N. The full InChI is InChI=1S/C26H30F2N4O5S.C25H29F2N5O5S.2C25H29F2N5O4S/c1-26(2,3)38(34,35)30-25(33)21-13-29-32-8-6-18(12-23(21)32)31-14-17(28)11-22(31)20-10-16(27)4-5-24(20)37-19-7-9-36-15-19;1-3-30(2)38(34,35)29-25(33)21-13-28-32-8-6-18(12-23(21)32)31-14-17(27)11-22(31)20-10-16(26)4-5-24(20)37-19-7-9-36-15-19;1-3-30(2)37(34,35)29-25(33)22-13-28-32-7-6-20(12-24(22)32)31-14-19(27)11-23(31)17-8-18(26)10-21(9-17)36-15-16-4-5-16;1-3-30(2)37(34,35)29-25(33)21-13-28-32-9-8-19(12-23(21)32)31-14-18(27)11-22(31)20-10-17(26)6-7-24(20)36-15-16-4-5-16/h4-6,8,10,12-13,17,19,22H,7,9,11,14-15H2,1-3H3,(H,30,33);4-6,8,10,12-13,17,19,22H,3,7,9,11,14-15H2,1-2H3,(H,29,33);6-10,12-13,16,19,23H,3-5,11,14-15H2,1-2H3,(H,29,33);6-10,12-13,16,18,22H,3-5,11,14-15H2,1-2H3,(H,29,33)/t2*17-,19?,22+;19-,23+;18-,22+/m0000/s1.

What are the key properties of N-tert-butylsulfonyl-5-[(2R,4S)-4-fluoro-2-[5-fluoro-2-(oxolan-3-yloxy)phenyl]pyrrolidin-1-yl]pyrazolo[1,5-a]pyridine-3-carboxamide;5-[(2R,4S)-2-[2-(cyclopropylmethoxy)-5-fluorophenyl]-4-fluoropyrrolidin-1-yl]-N-[ethyl(methyl)sulfamoyl]pyrazolo[1,5-a]pyridine-3-carboxamide;5-[(2R,4S)-2-[3-(cyclopropylmethoxy)-5-fluorophenyl]-4-fluoropyrrolidin-1-yl]-N-[ethyl(methyl)sulfamoyl]pyrazolo[1,5-a]pyridine-3-carboxamide;N-[ethyl(methyl)sulfamoyl]-5-[(2R,4S)-4-fluoro-2-[5-fluoro-2-(oxolan-3-yloxy)phenyl]pyrrolidin-1-yl]pyrazolo[1,5-a]pyridine-3-carboxamide?

N-tert-butylsulfonyl-5-[(2R,4S)-4-fluoro-2-[5-fluoro-2-(oxolan-3-yloxy)phenyl]pyrrolidin-1-yl]pyrazolo[1,5-a]pyridine-3-carboxamide;5-[(2R,4S)-2-[2-(cyclopropylmethoxy)-5-fluorophenyl]-4-fluoropyrrolidin-1-yl]-N-[ethyl(methyl)sulfamoyl]pyrazolo[1,5-a]pyridine-3-carboxamide;5-[(2R,4S)-2-[3-(cyclopropylmethoxy)-5-fluorophenyl]-4-fluoropyrrolidin-1-yl]-N-[ethyl(methyl)sulfamoyl]pyrazolo[1,5-a]pyridine-3-carboxamide;N-[ethyl(methyl)sulfamoyl]-5-[(2R,4S)-4-fluoro-2-[5-fluoro-2-(oxolan-3-yloxy)phenyl]pyrrolidin-1-yl]pyrazolo[1,5-a]pyridine-3-carboxamide has a molecular weight of 2165.41 g/mol, XLogP of 13.60, 32 rotatable bonds, 4 hydrogen bond donors, and 30 hydrogen bond acceptors.

Where does this data come from?

All data for N-tert-butylsulfonyl-5-[(2R,4S)-4-fluoro-2-[5-fluoro-2-(oxolan-3-yloxy)phenyl]pyrrolidin-1-yl]pyrazolo[1,5-a]pyridine-3-carboxamide;5-[(2R,4S)-2-[2-(cyclopropylmethoxy)-5-fluorophenyl]-4-fluoropyrrolidin-1-yl]-N-[ethyl(methyl)sulfamoyl]pyrazolo[1,5-a]pyridine-3-carboxamide;5-[(2R,4S)-2-[3-(cyclopropylmethoxy)-5-fluorophenyl]-4-fluoropyrrolidin-1-yl]-N-[ethyl(methyl)sulfamoyl]pyrazolo[1,5-a]pyridine-3-carboxamide;N-[ethyl(methyl)sulfamoyl]-5-[(2R,4S)-4-fluoro-2-[5-fluoro-2-(oxolan-3-yloxy)phenyl]pyrrolidin-1-yl]pyrazolo[1,5-a]pyridine-3-carboxamide is sourced from PubChem (CID 157102152), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).