N-(1,3-benzodioxol-5-yl)-5-[5-[(4-hydroxypiperidin-1-yl)methyl]-3-pyridinyl]-1H-indazole-3-carboxamide;N-(1,3-benzodioxol-5-yl)-5-[5-(morpholin-4-ylmethyl)-3-pyridinyl]-1H-indazole-3-carboxamide;N-(1,3-benzodioxol-5-yl)-5-(5-phenoxy-3-pyridinyl)-1H-indazole-3-carboxamide;5-[5-[(3,3-difluoropyrrolidin-1-yl)methyl]-3-pyridinyl]-N-pyridin-4-yl-1H-indazole-3-carboxamide

C100H86F2N20O13 — CID 157121537

About N-(1,3-benzodioxol-5-yl)-5-[5-[(4-hydroxypiperidin-1-yl)methyl]-3-pyridinyl]-1H-indazole-3-carboxamide;N-(1,3-benzodioxol-5-yl)-5-[5-(morpholin-4-ylmethyl)-3-pyridinyl]-1H-indazole-3-carboxamide;N-(1,3-benzodioxol-5-yl)-5-(5-phenoxy-3-pyridinyl)-1H-indazole-3-carboxamide;5-[5-[(3,3-difluoropyrrolidin-1-yl)methyl]-3-pyridinyl]-N-pyridin-4-yl-1H-indazole-3-carboxamide

N-(1,3-benzodioxol-5-yl)-5-[5-[(4-hydroxypiperidin-1-yl)methyl]-3-pyridinyl]-1H-indazole-3-carboxamide;N-(1,3-benzodioxol-5-yl)-5-[5-(morpholin-4-ylmethyl)-3-pyridinyl]-1H-indazole-3-carboxamide;N-(1,3-benzodioxol-5-yl)-5-(5-phenoxy-3-pyridinyl)-1H-indazole-3-carboxamide;5-[5-[(3,3-difluoropyrrolidin-1-yl)methyl]-3-pyridinyl]-N-pyridin-4-yl-1H-indazole-3-carboxamide (PubChem CID 157121537) has the molecular formula C100H86F2N20O13 and a molecular weight of 1813.91 g/mol. Its IUPAC name is N-(1,3-benzodioxol-5-yl)-5-[5-[(4-hydroxypiperidin-1-yl)methyl]-3-pyridinyl]-1H-indazole-3-carboxamide;N-(1,3-benzodioxol-5-yl)-5-[5-(morpholin-4-ylmethyl)-3-pyridinyl]-1H-indazole-3-carboxamide;N-(1,3-benzodioxol-5-yl)-5-(5-phenoxy-3-pyridinyl)-1H-indazole-3-carboxamide;5-[5-[(3,3-difluoropyrrolidin-1-yl)methyl]-3-pyridinyl]-N-pyridin-4-yl-1H-indazole-3-carboxamide.

Molecular Properties

• Compound Name: N-(1,3-benzodioxol-5-yl)-5-[5-[(4-hydroxypiperidin-1-yl)methyl]-3-pyridinyl]-1H-indazole-3-carboxamide;N-(1,3-benzodioxol-5-yl)-5-[5-(morpholin-4-ylmethyl)-3-pyridinyl]-1H-indazole-3-carboxamide;N-(1,3-benzodioxol-5-yl)-5-(5-phenoxy-3-pyridinyl)-1H-indazole-3-carboxamide;5-[5-[(3,3-difluoropyrrolidin-1-yl)methyl]-3-pyridinyl]-N-pyridin-4-yl-1H-indazole-3-carboxamide
• PubChem CID: 157121537
• Molecular Formula: C100H86F2N20O13
• Molecular Weight: 1813.91 g/mol
• Exact Mass: 1812.67
• IUPAC Name: N-(1,3-benzodioxol-5-yl)-5-[5-[(4-hydroxypiperidin-1-yl)methyl]-3-pyridinyl]-1H-indazole-3-carboxamide;N-(1,3-benzodioxol-5-yl)-5-[5-(morpholin-4-ylmethyl)-3-pyridinyl]-1H-indazole-3-carboxamide;N-(1,3-benzodioxol-5-yl)-5-(5-phenoxy-3-pyridinyl)-1H-indazole-3-carboxamide;5-[5-[(3,3-difluoropyrrolidin-1-yl)methyl]-3-pyridinyl]-N-pyridin-4-yl-1H-indazole-3-carboxamide
• SMILES: O=C(Nc1ccc2c(c1)OCO2)c1n[nH]c2ccc(-c3cncc(CN4CCC(O)CC4)c3)cc12.O=C(Nc1ccc2c(c1)OCO2)c1n[nH]c2ccc(-c3cncc(CN4CCOCC4)c3)cc12.O=C(Nc1ccc2c(c1)OCO2)c1n[nH]c2ccc(-c3cncc(Oc4ccccc4)c3)cc12.O=C(Nc1ccncc1)c1n[nH]c2ccc(-c3cncc(CN4CCC(F)(F)C4)c3)cc12
• InChI: InChI=1S/C26H25N5O4.C26H18N4O4.C25H23N5O4.C23H20F2N6O/c32-20-5-7-31(8-6-20)14-16-9-18(13-27-12-16)17-1-3-22-21(10-17)25(30-29-22)26(33)28-19-2-4-23-24(11-19)35-15-34-23;31-26(28-18-7-9-23-24(12-18)33-15-32-23)25-21-11-16(6-8-22(21)29-30-25)17-10-20(14-27-13-17)34-19-4-2-1-3-5-19;31-25(27-19-2-4-22-23(11-19)34-15-33-22)24-20-10-17(1-3-21(20)28-29-24)18-9-16(12-26-13-18)14-30-5-7-32-8-6-30;24-23(25)5-8-31(14-23)13-15-9-17(12-27-11-15)16-1-2-20-19(10-16)21(30-29-20)22(32)28-18-3-6-26-7-4-18/h1-4,9-13,20,32H,5-8,14-15H2,(H,28,33)(H,29,30);1-14H,15H2,(H,28,31)(H,29,30);1-4,9-13H,5-8,14-15H2,(H,27,31)(H,28,29);1-4,6-7,9-12H,5,8,13-14H2,(H,29,30)(H,26,28,32)
• InChIKey: AIAKQTXQYKDPOV-UHFFFAOYSA-N
• XLogP: 16.51
• TPSA: 399.36 Ų
• H-Bond Donors: 9
• H-Bond Acceptors: 25
• Rotatable Bonds: 20
• Heavy Atoms: 135
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	1813.91
LogP ≤ 5	16.51
H-Bond Donors ≤ 5	9
H-Bond Acceptors ≤ 10	25

Frequently Asked Questions

What is the IUPAC name of N-(1,3-benzodioxol-5-yl)-5-[5-[(4-hydroxypiperidin-1-yl)methyl]-3-pyridinyl]-1H-indazole-3-carboxamide;N-(1,3-benzodioxol-5-yl)-5-[5-(morpholin-4-ylmethyl)-3-pyridinyl]-1H-indazole-3-carboxamide;N-(1,3-benzodioxol-5-yl)-5-(5-phenoxy-3-pyridinyl)-1H-indazole-3-carboxamide;5-[5-[(3,3-difluoropyrrolidin-1-yl)methyl]-3-pyridinyl]-N-pyridin-4-yl-1H-indazole-3-carboxamide?

The IUPAC name of N-(1,3-benzodioxol-5-yl)-5-[5-[(4-hydroxypiperidin-1-yl)methyl]-3-pyridinyl]-1H-indazole-3-carboxamide;N-(1,3-benzodioxol-5-yl)-5-[5-(morpholin-4-ylmethyl)-3-pyridinyl]-1H-indazole-3-carboxamide;N-(1,3-benzodioxol-5-yl)-5-(5-phenoxy-3-pyridinyl)-1H-indazole-3-carboxamide;5-[5-[(3,3-difluoropyrrolidin-1-yl)methyl]-3-pyridinyl]-N-pyridin-4-yl-1H-indazole-3-carboxamide (CID 157121537) is N-(1,3-benzodioxol-5-yl)-5-[5-[(4-hydroxypiperidin-1-yl)methyl]-3-pyridinyl]-1H-indazole-3-carboxamide;N-(1,3-benzodioxol-5-yl)-5-[5-(morpholin-4-ylmethyl)-3-pyridinyl]-1H-indazole-3-carboxamide;N-(1,3-benzodioxol-5-yl)-5-(5-phenoxy-3-pyridinyl)-1H-indazole-3-carboxamide;5-[5-[(3,3-difluoropyrrolidin-1-yl)methyl]-3-pyridinyl]-N-pyridin-4-yl-1H-indazole-3-carboxamide.

What is the SMILES notation for N-(1,3-benzodioxol-5-yl)-5-[5-[(4-hydroxypiperidin-1-yl)methyl]-3-pyridinyl]-1H-indazole-3-carboxamide;N-(1,3-benzodioxol-5-yl)-5-[5-(morpholin-4-ylmethyl)-3-pyridinyl]-1H-indazole-3-carboxamide;N-(1,3-benzodioxol-5-yl)-5-(5-phenoxy-3-pyridinyl)-1H-indazole-3-carboxamide;5-[5-[(3,3-difluoropyrrolidin-1-yl)methyl]-3-pyridinyl]-N-pyridin-4-yl-1H-indazole-3-carboxamide?

The canonical SMILES for N-(1,3-benzodioxol-5-yl)-5-[5-[(4-hydroxypiperidin-1-yl)methyl]-3-pyridinyl]-1H-indazole-3-carboxamide;N-(1,3-benzodioxol-5-yl)-5-[5-(morpholin-4-ylmethyl)-3-pyridinyl]-1H-indazole-3-carboxamide;N-(1,3-benzodioxol-5-yl)-5-(5-phenoxy-3-pyridinyl)-1H-indazole-3-carboxamide;5-[5-[(3,3-difluoropyrrolidin-1-yl)methyl]-3-pyridinyl]-N-pyridin-4-yl-1H-indazole-3-carboxamide is O=C(Nc1ccc2c(c1)OCO2)c1n[nH]c2ccc(-c3cncc(CN4CCC(O)CC4)c3)cc12.O=C(Nc1ccc2c(c1)OCO2)c1n[nH]c2ccc(-c3cncc(CN4CCOCC4)c3)cc12.O=C(Nc1ccc2c(c1)OCO2)c1n[nH]c2ccc(-c3cncc(Oc4ccccc4)c3)cc12.O=C(Nc1ccncc1)c1n[nH]c2ccc(-c3cncc(CN4CCC(F)(F)C4)c3)cc12.

What is the InChIKey of N-(1,3-benzodioxol-5-yl)-5-[5-[(4-hydroxypiperidin-1-yl)methyl]-3-pyridinyl]-1H-indazole-3-carboxamide;N-(1,3-benzodioxol-5-yl)-5-[5-(morpholin-4-ylmethyl)-3-pyridinyl]-1H-indazole-3-carboxamide;N-(1,3-benzodioxol-5-yl)-5-(5-phenoxy-3-pyridinyl)-1H-indazole-3-carboxamide;5-[5-[(3,3-difluoropyrrolidin-1-yl)methyl]-3-pyridinyl]-N-pyridin-4-yl-1H-indazole-3-carboxamide?

The InChIKey is AIAKQTXQYKDPOV-UHFFFAOYSA-N. The full InChI is InChI=1S/C26H25N5O4.C26H18N4O4.C25H23N5O4.C23H20F2N6O/c32-20-5-7-31(8-6-20)14-16-9-18(13-27-12-16)17-1-3-22-21(10-17)25(30-29-22)26(33)28-19-2-4-23-24(11-19)35-15-34-23;31-26(28-18-7-9-23-24(12-18)33-15-32-23)25-21-11-16(6-8-22(21)29-30-25)17-10-20(14-27-13-17)34-19-4-2-1-3-5-19;31-25(27-19-2-4-22-23(11-19)34-15-33-22)24-20-10-17(1-3-21(20)28-29-24)18-9-16(12-26-13-18)14-30-5-7-32-8-6-30;24-23(25)5-8-31(14-23)13-15-9-17(12-27-11-15)16-1-2-20-19(10-16)21(30-29-20)22(32)28-18-3-6-26-7-4-18/h1-4,9-13,20,32H,5-8,14-15H2,(H,28,33)(H,29,30);1-14H,15H2,(H,28,31)(H,29,30);1-4,9-13H,5-8,14-15H2,(H,27,31)(H,28,29);1-4,6-7,9-12H,5,8,13-14H2,(H,29,30)(H,26,28,32).

What are the key properties of N-(1,3-benzodioxol-5-yl)-5-[5-[(4-hydroxypiperidin-1-yl)methyl]-3-pyridinyl]-1H-indazole-3-carboxamide;N-(1,3-benzodioxol-5-yl)-5-[5-(morpholin-4-ylmethyl)-3-pyridinyl]-1H-indazole-3-carboxamide;N-(1,3-benzodioxol-5-yl)-5-(5-phenoxy-3-pyridinyl)-1H-indazole-3-carboxamide;5-[5-[(3,3-difluoropyrrolidin-1-yl)methyl]-3-pyridinyl]-N-pyridin-4-yl-1H-indazole-3-carboxamide?

N-(1,3-benzodioxol-5-yl)-5-[5-[(4-hydroxypiperidin-1-yl)methyl]-3-pyridinyl]-1H-indazole-3-carboxamide;N-(1,3-benzodioxol-5-yl)-5-[5-(morpholin-4-ylmethyl)-3-pyridinyl]-1H-indazole-3-carboxamide;N-(1,3-benzodioxol-5-yl)-5-(5-phenoxy-3-pyridinyl)-1H-indazole-3-carboxamide;5-[5-[(3,3-difluoropyrrolidin-1-yl)methyl]-3-pyridinyl]-N-pyridin-4-yl-1H-indazole-3-carboxamide has a molecular weight of 1813.91 g/mol, XLogP of 16.51, 20 rotatable bonds, 9 hydrogen bond donors, and 25 hydrogen bond acceptors.

Where does this data come from?

All data for N-(1,3-benzodioxol-5-yl)-5-[5-[(4-hydroxypiperidin-1-yl)methyl]-3-pyridinyl]-1H-indazole-3-carboxamide;N-(1,3-benzodioxol-5-yl)-5-[5-(morpholin-4-ylmethyl)-3-pyridinyl]-1H-indazole-3-carboxamide;N-(1,3-benzodioxol-5-yl)-5-(5-phenoxy-3-pyridinyl)-1H-indazole-3-carboxamide;5-[5-[(3,3-difluoropyrrolidin-1-yl)methyl]-3-pyridinyl]-N-pyridin-4-yl-1H-indazole-3-carboxamide is sourced from PubChem (CID 157121537), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).