N-(4-chlorophenyl)-6-(6-fluoro-2-methylbenzimidazol-1-yl)pyrazin-2-amine;1-[6-[4-(difluoromethoxy)-3-fluoroanilino]pyrazin-2-yl]-N-[4-(difluoromethoxy)-3-fluorophenyl]-2-ethylimidazo[4,5-b]pyridin-6-amine;6-(2-ethyl-5-fluoropyrazolo[1,5-a]pyridin-3-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;6-(6-fluoro-2-methylbenzimidazol-1-yl)-N-(4-methoxyphenyl)pyrazin-2-amine;6-(6-fluoro-2-methylbenzimidazol-1-yl)-N-(4-methylphenyl)pyrazin-2-amine

C102H79ClF13N27O3 — CID 157131555

IUPACN-(4-chlorophenyl)-6-(6-fluoro-2-methylbenzimidazol-1-yl)pyrazin-2-amine;1-[6-[4-(difluoromethoxy)-3-fluoroanilino]pyrazin-2-yl]-N-[4-(difluoromethoxy)-3-fluorophenyl]-2-ethylimidazo[4,5-b]pyridin-6-amine;6-(2-ethyl-5-fluoropyrazolo[1,5-a]pyridin-3-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;6-(6-fluoro-2-methylbenzimidazol-1-yl)-N-(4-methoxyphenyl)pyrazin-2-amine;6-(6-fluoro-2-methylbenzimidazol-1-yl)-N-(4-methylphenyl)pyrazin-2-amine
SMILESCCc1nc2ncc(Nc3ccc(OC(F)F)c(F)c3)cc2n1-c1cncc(Nc2ccc(OC(F)F)c(F)c2)n1.CCc1nn2ccc(F)cc2c1-c1cncc(Nc2ccc(C(F)(F)F)cc2)n1.COc1ccc(Nc2cncc(-n3c(C)nc4ccc(F)cc43)n2)cc1.Cc1ccc(Nc2cncc(-n3c(C)nc4ccc(F)cc43)n2)cc1.Cc1nc2ccc(F)cc2n1-c1cncc(Nc2ccc(Cl)cc2)n1
InChIInChI=1S/C26H19F6N7O2.C20H15F4N5.C19H16FN5O.C19H16FN5.C18H13ClFN5/c1-2-22-38-24-18(9-15(10-34-24)35-13-3-5-19(16(27)7-13)40-25(29)30)39(22)23-12-33-11-21(37-23)36-14-4-6-20(17(28)8-14)41-26(31)32;1-2-15-19(17-9-13(21)7-8-29(17)28-15)16-10-25-11-18(27-16)26-14-5-3-12(4-6-14)20(22,23)24;1-12-22-16-8-3-13(20)9-17(16)25(12)19-11-21-10-18(24-19)23-14-4-6-15(26-2)7-5-14;1-12-3-6-15(7-4-12)23-18-10-21-11-19(24-18)25-13(2)22-16-8-5-14(20)9-17(16)25;1-11-22-15-7-4-13(20)8-16(15)25(11)18-10-21-9-17(24-18)23-14-5-2-12(19)3-6-14/h3-12,25-26,35H,2H2,1H3,(H,36,37);3-11H,2H2,1H3,(H,26,27);3-11H,1-2H3,(H,23,24);3-11H,1-2H3,(H,23,24);2-10H,1H3,(H,23,24)
InChIKeyAJDFNJBTFNECCF-UHFFFAOYSA-N
MW2013.37 g/mol
LogP24.99
Rot. Bonds24

About N-(4-chlorophenyl)-6-(6-fluoro-2-methylbenzimidazol-1-yl)pyrazin-2-amine;1-[6-[4-(difluoromethoxy)-3-fluoroanilino]pyrazin-2-yl]-N-[4-(difluoromethoxy)-3-fluorophenyl]-2-ethylimidazo[4,5-b]pyridin-6-amine;6-(2-ethyl-5-fluoropyrazolo[1,5-a]pyridin-3-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;6-(6-fluoro-2-methylbenzimidazol-1-yl)-N-(4-methoxyphenyl)pyrazin-2-amine;6-(6-fluoro-2-methylbenzimidazol-1-yl)-N-(4-methylphenyl)pyrazin-2-amine

N-(4-chlorophenyl)-6-(6-fluoro-2-methylbenzimidazol-1-yl)pyrazin-2-amine;1-[6-[4-(difluoromethoxy)-3-fluoroanilino]pyrazin-2-yl]-N-[4-(difluoromethoxy)-3-fluorophenyl]-2-ethylimidazo[4,5-b]pyridin-6-amine;6-(2-ethyl-5-fluoropyrazolo[1,5-a]pyridin-3-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;6-(6-fluoro-2-methylbenzimidazol-1-yl)-N-(4-methoxyphenyl)pyrazin-2-amine;6-(6-fluoro-2-methylbenzimidazol-1-yl)-N-(4-methylphenyl)pyrazin-2-amine (PubChem CID 157131555) has the molecular formula C102H79ClF13N27O3 and a molecular weight of 2013.37 g/mol. Its IUPAC name is N-(4-chlorophenyl)-6-(6-fluoro-2-methylbenzimidazol-1-yl)pyrazin-2-amine;1-[6-[4-(difluoromethoxy)-3-fluoroanilino]pyrazin-2-yl]-N-[4-(difluoromethoxy)-3-fluorophenyl]-2-ethylimidazo[4,5-b]pyridin-6-amine;6-(2-ethyl-5-fluoropyrazolo[1,5-a]pyridin-3-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;6-(6-fluoro-2-methylbenzimidazol-1-yl)-N-(4-methoxyphenyl)pyrazin-2-amine;6-(6-fluoro-2-methylbenzimidazol-1-yl)-N-(4-methylphenyl)pyrazin-2-amine.

Molecular Properties

Compound NameN-(4-chlorophenyl)-6-(6-fluoro-2-methylbenzimidazol-1-yl)pyrazin-2-amine;1-[6-[4-(difluoromethoxy)-3-fluoroanilino]pyrazin-2-yl]-N-[4-(difluoromethoxy)-3-fluorophenyl]-2-ethylimidazo[4,5-b]pyridin-6-amine;6-(2-ethyl-5-fluoropyrazolo[1,5-a]pyridin-3-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;6-(6-fluoro-2-methylbenzimidazol-1-yl)-N-(4-methoxyphenyl)pyrazin-2-amine;6-(6-fluoro-2-methylbenzimidazol-1-yl)-N-(4-methylphenyl)pyrazin-2-amine
PubChem CID157131555
Molecular FormulaC102H79ClF13N27O3
Molecular Weight2013.37 g/mol
Exact Mass2011.63
IUPAC NameN-(4-chlorophenyl)-6-(6-fluoro-2-methylbenzimidazol-1-yl)pyrazin-2-amine;1-[6-[4-(difluoromethoxy)-3-fluoroanilino]pyrazin-2-yl]-N-[4-(difluoromethoxy)-3-fluorophenyl]-2-ethylimidazo[4,5-b]pyridin-6-amine;6-(2-ethyl-5-fluoropyrazolo[1,5-a]pyridin-3-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;6-(6-fluoro-2-methylbenzimidazol-1-yl)-N-(4-methoxyphenyl)pyrazin-2-amine;6-(6-fluoro-2-methylbenzimidazol-1-yl)-N-(4-methylphenyl)pyrazin-2-amine
SMILESCCc1nc2ncc(Nc3ccc(OC(F)F)c(F)c3)cc2n1-c1cncc(Nc2ccc(OC(F)F)c(F)c2)n1.CCc1nn2ccc(F)cc2c1-c1cncc(Nc2ccc(C(F)(F)F)cc2)n1.COc1ccc(Nc2cncc(-n3c(C)nc4ccc(F)cc43)n2)cc1.Cc1ccc(Nc2cncc(-n3c(C)nc4ccc(F)cc43)n2)cc1.Cc1nc2ccc(F)cc2n1-c1cncc(Nc2ccc(Cl)cc2)n1
InChIInChI=1S/C26H19F6N7O2.C20H15F4N5.C19H16FN5O.C19H16FN5.C18H13ClFN5/c1-2-22-38-24-18(9-15(10-34-24)35-13-3-5-19(16(27)7-13)40-25(29)30)39(22)23-12-33-11-21(37-23)36-14-4-6-20(17(28)8-14)41-26(31)32;1-2-15-19(17-9-13(21)7-8-29(17)28-15)16-10-25-11-18(27-16)26-14-5-3-12(4-6-14)20(22,23)24;1-12-22-16-8-3-13(20)9-17(16)25(12)19-11-21-10-18(24-19)23-14-4-6-15(26-2)7-5-14;1-12-3-6-15(7-4-12)23-18-10-21-11-19(24-18)25-13(2)22-16-8-5-14(20)9-17(16)25;1-11-22-15-7-4-13(20)8-16(15)25(11)18-10-21-9-17(24-18)23-14-5-2-12(19)3-6-14/h3-12,25-26,35H,2H2,1H3,(H,36,37);3-11H,2H2,1H3,(H,26,27);3-11H,1-2H3,(H,23,24);3-11H,1-2H3,(H,23,24);2-10H,1H3,(H,23,24)
InChIKeyAJDFNJBTFNECCF-UHFFFAOYSA-N
XLogP24.99
TPSA330.24 Ų
H-Bond Donors6
H-Bond Acceptors30
Rotatable Bonds24
Heavy Atoms146
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5002013.37
LogP ≤ 524.99
H-Bond Donors ≤ 56
H-Bond Acceptors ≤ 1030

Analyze N-(4-chlorophenyl)-6-(6-fluoro-2-methylbenzimidazol-1-yl)pyrazin-2-amine;1-[6-[4-(difluoromethoxy)-3-fluoroanilino]pyrazin-2-yl]-N-[4-(difluoromethoxy)-3-fluorophenyl]-2-ethylimidazo[4,5-b]pyridin-6-amine;6-(2-ethyl-5-fluoropyrazolo[1,5-a]pyridin-3-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;6-(6-fluoro-2-methylbenzimidazol-1-yl)-N-(4-methoxyphenyl)pyrazin-2-amine;6-(6-fluoro-2-methylbenzimidazol-1-yl)-N-(4-methylphenyl)pyrazin-2-amine with MolForge

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Frequently Asked Questions

What is the IUPAC name of N-(4-chlorophenyl)-6-(6-fluoro-2-methylbenzimidazol-1-yl)pyrazin-2-amine;1-[6-[4-(difluoromethoxy)-3-fluoroanilino]pyrazin-2-yl]-N-[4-(difluoromethoxy)-3-fluorophenyl]-2-ethylimidazo[4,5-b]pyridin-6-amine;6-(2-ethyl-5-fluoropyrazolo[1,5-a]pyridin-3-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;6-(6-fluoro-2-methylbenzimidazol-1-yl)-N-(4-methoxyphenyl)pyrazin-2-amine;6-(6-fluoro-2-methylbenzimidazol-1-yl)-N-(4-methylphenyl)pyrazin-2-amine?
The IUPAC name of N-(4-chlorophenyl)-6-(6-fluoro-2-methylbenzimidazol-1-yl)pyrazin-2-amine;1-[6-[4-(difluoromethoxy)-3-fluoroanilino]pyrazin-2-yl]-N-[4-(difluoromethoxy)-3-fluorophenyl]-2-ethylimidazo[4,5-b]pyridin-6-amine;6-(2-ethyl-5-fluoropyrazolo[1,5-a]pyridin-3-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;6-(6-fluoro-2-methylbenzimidazol-1-yl)-N-(4-methoxyphenyl)pyrazin-2-amine;6-(6-fluoro-2-methylbenzimidazol-1-yl)-N-(4-methylphenyl)pyrazin-2-amine (CID 157131555) is N-(4-chlorophenyl)-6-(6-fluoro-2-methylbenzimidazol-1-yl)pyrazin-2-amine;1-[6-[4-(difluoromethoxy)-3-fluoroanilino]pyrazin-2-yl]-N-[4-(difluoromethoxy)-3-fluorophenyl]-2-ethylimidazo[4,5-b]pyridin-6-amine;6-(2-ethyl-5-fluoropyrazolo[1,5-a]pyridin-3-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;6-(6-fluoro-2-methylbenzimidazol-1-yl)-N-(4-methoxyphenyl)pyrazin-2-amine;6-(6-fluoro-2-methylbenzimidazol-1-yl)-N-(4-methylphenyl)pyrazin-2-amine.
What is the SMILES notation for N-(4-chlorophenyl)-6-(6-fluoro-2-methylbenzimidazol-1-yl)pyrazin-2-amine;1-[6-[4-(difluoromethoxy)-3-fluoroanilino]pyrazin-2-yl]-N-[4-(difluoromethoxy)-3-fluorophenyl]-2-ethylimidazo[4,5-b]pyridin-6-amine;6-(2-ethyl-5-fluoropyrazolo[1,5-a]pyridin-3-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;6-(6-fluoro-2-methylbenzimidazol-1-yl)-N-(4-methoxyphenyl)pyrazin-2-amine;6-(6-fluoro-2-methylbenzimidazol-1-yl)-N-(4-methylphenyl)pyrazin-2-amine?
The canonical SMILES for N-(4-chlorophenyl)-6-(6-fluoro-2-methylbenzimidazol-1-yl)pyrazin-2-amine;1-[6-[4-(difluoromethoxy)-3-fluoroanilino]pyrazin-2-yl]-N-[4-(difluoromethoxy)-3-fluorophenyl]-2-ethylimidazo[4,5-b]pyridin-6-amine;6-(2-ethyl-5-fluoropyrazolo[1,5-a]pyridin-3-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;6-(6-fluoro-2-methylbenzimidazol-1-yl)-N-(4-methoxyphenyl)pyrazin-2-amine;6-(6-fluoro-2-methylbenzimidazol-1-yl)-N-(4-methylphenyl)pyrazin-2-amine is CCc1nc2ncc(Nc3ccc(OC(F)F)c(F)c3)cc2n1-c1cncc(Nc2ccc(OC(F)F)c(F)c2)n1.CCc1nn2ccc(F)cc2c1-c1cncc(Nc2ccc(C(F)(F)F)cc2)n1.COc1ccc(Nc2cncc(-n3c(C)nc4ccc(F)cc43)n2)cc1.Cc1ccc(Nc2cncc(-n3c(C)nc4ccc(F)cc43)n2)cc1.Cc1nc2ccc(F)cc2n1-c1cncc(Nc2ccc(Cl)cc2)n1.
What is the InChIKey of N-(4-chlorophenyl)-6-(6-fluoro-2-methylbenzimidazol-1-yl)pyrazin-2-amine;1-[6-[4-(difluoromethoxy)-3-fluoroanilino]pyrazin-2-yl]-N-[4-(difluoromethoxy)-3-fluorophenyl]-2-ethylimidazo[4,5-b]pyridin-6-amine;6-(2-ethyl-5-fluoropyrazolo[1,5-a]pyridin-3-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;6-(6-fluoro-2-methylbenzimidazol-1-yl)-N-(4-methoxyphenyl)pyrazin-2-amine;6-(6-fluoro-2-methylbenzimidazol-1-yl)-N-(4-methylphenyl)pyrazin-2-amine?
The InChIKey is AJDFNJBTFNECCF-UHFFFAOYSA-N. The full InChI is InChI=1S/C26H19F6N7O2.C20H15F4N5.C19H16FN5O.C19H16FN5.C18H13ClFN5/c1-2-22-38-24-18(9-15(10-34-24)35-13-3-5-19(16(27)7-13)40-25(29)30)39(22)23-12-33-11-21(37-23)36-14-4-6-20(17(28)8-14)41-26(31)32;1-2-15-19(17-9-13(21)7-8-29(17)28-15)16-10-25-11-18(27-16)26-14-5-3-12(4-6-14)20(22,23)24;1-12-22-16-8-3-13(20)9-17(16)25(12)19-11-21-10-18(24-19)23-14-4-6-15(26-2)7-5-14;1-12-3-6-15(7-4-12)23-18-10-21-11-19(24-18)25-13(2)22-16-8-5-14(20)9-17(16)25;1-11-22-15-7-4-13(20)8-16(15)25(11)18-10-21-9-17(24-18)23-14-5-2-12(19)3-6-14/h3-12,25-26,35H,2H2,1H3,(H,36,37);3-11H,2H2,1H3,(H,26,27);3-11H,1-2H3,(H,23,24);3-11H,1-2H3,(H,23,24);2-10H,1H3,(H,23,24).
What are the key properties of N-(4-chlorophenyl)-6-(6-fluoro-2-methylbenzimidazol-1-yl)pyrazin-2-amine;1-[6-[4-(difluoromethoxy)-3-fluoroanilino]pyrazin-2-yl]-N-[4-(difluoromethoxy)-3-fluorophenyl]-2-ethylimidazo[4,5-b]pyridin-6-amine;6-(2-ethyl-5-fluoropyrazolo[1,5-a]pyridin-3-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;6-(6-fluoro-2-methylbenzimidazol-1-yl)-N-(4-methoxyphenyl)pyrazin-2-amine;6-(6-fluoro-2-methylbenzimidazol-1-yl)-N-(4-methylphenyl)pyrazin-2-amine?
N-(4-chlorophenyl)-6-(6-fluoro-2-methylbenzimidazol-1-yl)pyrazin-2-amine;1-[6-[4-(difluoromethoxy)-3-fluoroanilino]pyrazin-2-yl]-N-[4-(difluoromethoxy)-3-fluorophenyl]-2-ethylimidazo[4,5-b]pyridin-6-amine;6-(2-ethyl-5-fluoropyrazolo[1,5-a]pyridin-3-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;6-(6-fluoro-2-methylbenzimidazol-1-yl)-N-(4-methoxyphenyl)pyrazin-2-amine;6-(6-fluoro-2-methylbenzimidazol-1-yl)-N-(4-methylphenyl)pyrazin-2-amine has a molecular weight of 2013.37 g/mol, XLogP of 24.99, 24 rotatable bonds, 6 hydrogen bond donors, and 30 hydrogen bond acceptors.
Where does this data come from?
All data for N-(4-chlorophenyl)-6-(6-fluoro-2-methylbenzimidazol-1-yl)pyrazin-2-amine;1-[6-[4-(difluoromethoxy)-3-fluoroanilino]pyrazin-2-yl]-N-[4-(difluoromethoxy)-3-fluorophenyl]-2-ethylimidazo[4,5-b]pyridin-6-amine;6-(2-ethyl-5-fluoropyrazolo[1,5-a]pyridin-3-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;6-(6-fluoro-2-methylbenzimidazol-1-yl)-N-(4-methoxyphenyl)pyrazin-2-amine;6-(6-fluoro-2-methylbenzimidazol-1-yl)-N-(4-methylphenyl)pyrazin-2-amine is sourced from PubChem (CID 157131555), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).