3-(difluoromethyl)-N-[4-methyl-3-(4-morpholin-4-yl-5,5-dioxo-6,7-dihydrothieno[3,2-d]pyrimidin-2-yl)phenyl]benzamide;3-(difluoromethyl)-N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-a]pyridin-6-yl)phenyl]benzamide;2-(difluoromethyl)-N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-a]pyridin-6-yl)phenyl]pyridine-4-carboxamide;2-(difluoromethyl)-N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-b]pyridazin-6-yl)phenyl]pyridine-4-carboxamide;N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-a]pyridin-6-yl)phenyl]-2-methylsulfonylpyridine-4-carboxamide;N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-a]pyridin-6-yl)phenyl]-4-propyl-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-a]pyridin-6-yl)phenyl]-6-(trifluoromethyl)pyridazine-4-carboxamide;N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-a]pyridin-6-yl)phenyl]-2-(trifluoromethyl)pyridine-4-carboxamide

C203H190F17N39O20S2 — CID 157132519

IUPAC3-(difluoromethyl)-N-[4-methyl-3-(4-morpholin-4-yl-5,5-dioxo-6,7-dihydrothieno[3,2-d]pyrimidin-2-yl)phenyl]benzamide;3-(difluoromethyl)-N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-a]pyridin-6-yl)phenyl]benzamide;2-(difluoromethyl)-N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-a]pyridin-6-yl)phenyl]pyridine-4-carboxamide;2-(difluoromethyl)-N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-b]pyridazin-6-yl)phenyl]pyridine-4-carboxamide;N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-a]pyridin-6-yl)phenyl]-2-methylsulfonylpyridine-4-carboxamide;N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-a]pyridin-6-yl)phenyl]-4-propyl-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-a]pyridin-6-yl)phenyl]-6-(trifluoromethyl)pyridazine-4-carboxamide;N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-a]pyridin-6-yl)phenyl]-2-(trifluoromethyl)pyridine-4-carboxamide
SMILESCCCc1ccc(C(=O)Nc2ccc(C)c(-c3cc(N4CCOCC4)c4nccn4c3)c2)cc1C(F)(F)F.Cc1ccc(NC(=O)c2cccc(C(F)F)c2)cc1-c1cc(N2CCOCC2)c2nccn2c1.Cc1ccc(NC(=O)c2cccc(C(F)F)c2)cc1-c1nc2c(c(N3CCOCC3)n1)S(=O)(=O)CC2.Cc1ccc(NC(=O)c2ccnc(C(F)(F)F)c2)cc1-c1cc(N2CCOCC2)c2nccn2c1.Cc1ccc(NC(=O)c2ccnc(C(F)F)c2)cc1-c1cc(N2CCOCC2)c2nccn2c1.Cc1ccc(NC(=O)c2ccnc(C(F)F)c2)cc1-c1cc(N2CCOCC2)c2nccn2n1.Cc1ccc(NC(=O)c2ccnc(S(C)(=O)=O)c2)cc1-c1cc(N2CCOCC2)c2nccn2c1.Cc1ccc(NC(=O)c2cnnc(C(F)(F)F)c2)cc1-c1cc(N2CCOCC2)c2nccn2c1
InChIInChI=1S/C29H29F3N4O2.C26H24F2N4O2.C25H22F3N5O2.C25H23F2N5O2.C25H24F2N4O4S.C25H25N5O4S.C24H21F3N6O2.C24H22F2N6O2/c1-3-4-20-6-7-21(15-25(20)29(30,31)32)28(37)34-23-8-5-19(2)24(17-23)22-16-26(35-11-13-38-14-12-35)27-33-9-10-36(27)18-22;1-17-5-6-21(30-26(33)19-4-2-3-18(13-19)24(27)28)15-22(17)20-14-23(31-9-11-34-12-10-31)25-29-7-8-32(25)16-20;1-16-2-3-19(31-24(34)17-4-5-29-22(13-17)25(26,27)28)14-20(16)18-12-21(32-8-10-35-11-9-32)23-30-6-7-33(23)15-18;1-16-2-3-19(30-25(33)17-4-5-28-21(12-17)23(26)27)14-20(16)18-13-22(31-8-10-34-11-9-31)24-29-6-7-32(24)15-18;1-15-5-6-18(28-25(32)17-4-2-3-16(13-17)22(26)27)14-19(15)23-29-20-7-12-36(33,34)21(20)24(30-23)31-8-10-35-11-9-31;1-17-3-4-20(28-25(31)18-5-6-26-23(14-18)35(2,32)33)15-21(17)19-13-22(29-9-11-34-12-10-29)24-27-7-8-30(24)16-19;1-15-2-3-18(30-23(34)16-11-21(24(25,26)27)31-29-13-16)12-19(15)17-10-20(32-6-8-35-9-7-32)22-28-4-5-33(22)14-17;1-15-2-3-17(29-24(33)16-4-5-27-20(12-16)22(25)26)13-18(15)19-14-21(31-8-10-34-11-9-31)23-28-6-7-32(23)30-19/h5-10,15-18H,3-4,11-14H2,1-2H3,(H,34,37);2-8,13-16,24H,9-12H2,1H3,(H,30,33);2-7,12-15H,8-11H2,1H3,(H,31,34);2-7,12-15,23H,8-11H2,1H3,(H,30,33);2-6,13-14,22H,7-12H2,1H3,(H,28,32);3-8,13-16H,9-12H2,1-2H3,(H,28,31);2-5,10-14H,6-9H2,1H3,(H,30,34);2-7,12-14,22H,8-11H2,1H3,(H,29,33)
InChIKeyAJFVGQULOWZFRJ-UHFFFAOYSA-N
MW3883.11 g/mol
LogP36.59
Rot. Bonds39

About 3-(difluoromethyl)-N-[4-methyl-3-(4-morpholin-4-yl-5,5-dioxo-6,7-dihydrothieno[3,2-d]pyrimidin-2-yl)phenyl]benzamide;3-(difluoromethyl)-N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-a]pyridin-6-yl)phenyl]benzamide;2-(difluoromethyl)-N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-a]pyridin-6-yl)phenyl]pyridine-4-carboxamide;2-(difluoromethyl)-N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-b]pyridazin-6-yl)phenyl]pyridine-4-carboxamide;N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-a]pyridin-6-yl)phenyl]-2-methylsulfonylpyridine-4-carboxamide;N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-a]pyridin-6-yl)phenyl]-4-propyl-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-a]pyridin-6-yl)phenyl]-6-(trifluoromethyl)pyridazine-4-carboxamide;N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-a]pyridin-6-yl)phenyl]-2-(trifluoromethyl)pyridine-4-carboxamide

3-(difluoromethyl)-N-[4-methyl-3-(4-morpholin-4-yl-5,5-dioxo-6,7-dihydrothieno[3,2-d]pyrimidin-2-yl)phenyl]benzamide;3-(difluoromethyl)-N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-a]pyridin-6-yl)phenyl]benzamide;2-(difluoromethyl)-N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-a]pyridin-6-yl)phenyl]pyridine-4-carboxamide;2-(difluoromethyl)-N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-b]pyridazin-6-yl)phenyl]pyridine-4-carboxamide;N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-a]pyridin-6-yl)phenyl]-2-methylsulfonylpyridine-4-carboxamide;N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-a]pyridin-6-yl)phenyl]-4-propyl-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-a]pyridin-6-yl)phenyl]-6-(trifluoromethyl)pyridazine-4-carboxamide;N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-a]pyridin-6-yl)phenyl]-2-(trifluoromethyl)pyridine-4-carboxamide (PubChem CID 157132519) has the molecular formula C203H190F17N39O20S2 and a molecular weight of 3883.11 g/mol. Its IUPAC name is 3-(difluoromethyl)-N-[4-methyl-3-(4-morpholin-4-yl-5,5-dioxo-6,7-dihydrothieno[3,2-d]pyrimidin-2-yl)phenyl]benzamide;3-(difluoromethyl)-N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-a]pyridin-6-yl)phenyl]benzamide;2-(difluoromethyl)-N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-a]pyridin-6-yl)phenyl]pyridine-4-carboxamide;2-(difluoromethyl)-N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-b]pyridazin-6-yl)phenyl]pyridine-4-carboxamide;N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-a]pyridin-6-yl)phenyl]-2-methylsulfonylpyridine-4-carboxamide;N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-a]pyridin-6-yl)phenyl]-4-propyl-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-a]pyridin-6-yl)phenyl]-6-(trifluoromethyl)pyridazine-4-carboxamide;N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-a]pyridin-6-yl)phenyl]-2-(trifluoromethyl)pyridine-4-carboxamide.

Molecular Properties

Compound Name3-(difluoromethyl)-N-[4-methyl-3-(4-morpholin-4-yl-5,5-dioxo-6,7-dihydrothieno[3,2-d]pyrimidin-2-yl)phenyl]benzamide;3-(difluoromethyl)-N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-a]pyridin-6-yl)phenyl]benzamide;2-(difluoromethyl)-N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-a]pyridin-6-yl)phenyl]pyridine-4-carboxamide;2-(difluoromethyl)-N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-b]pyridazin-6-yl)phenyl]pyridine-4-carboxamide;N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-a]pyridin-6-yl)phenyl]-2-methylsulfonylpyridine-4-carboxamide;N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-a]pyridin-6-yl)phenyl]-4-propyl-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-a]pyridin-6-yl)phenyl]-6-(trifluoromethyl)pyridazine-4-carboxamide;N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-a]pyridin-6-yl)phenyl]-2-(trifluoromethyl)pyridine-4-carboxamide
PubChem CID157132519
Molecular FormulaC203H190F17N39O20S2
Molecular Weight3883.11 g/mol
Exact Mass3880.42
IUPAC Name3-(difluoromethyl)-N-[4-methyl-3-(4-morpholin-4-yl-5,5-dioxo-6,7-dihydrothieno[3,2-d]pyrimidin-2-yl)phenyl]benzamide;3-(difluoromethyl)-N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-a]pyridin-6-yl)phenyl]benzamide;2-(difluoromethyl)-N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-a]pyridin-6-yl)phenyl]pyridine-4-carboxamide;2-(difluoromethyl)-N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-b]pyridazin-6-yl)phenyl]pyridine-4-carboxamide;N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-a]pyridin-6-yl)phenyl]-2-methylsulfonylpyridine-4-carboxamide;N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-a]pyridin-6-yl)phenyl]-4-propyl-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-a]pyridin-6-yl)phenyl]-6-(trifluoromethyl)pyridazine-4-carboxamide;N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-a]pyridin-6-yl)phenyl]-2-(trifluoromethyl)pyridine-4-carboxamide
SMILESCCCc1ccc(C(=O)Nc2ccc(C)c(-c3cc(N4CCOCC4)c4nccn4c3)c2)cc1C(F)(F)F.Cc1ccc(NC(=O)c2cccc(C(F)F)c2)cc1-c1cc(N2CCOCC2)c2nccn2c1.Cc1ccc(NC(=O)c2cccc(C(F)F)c2)cc1-c1nc2c(c(N3CCOCC3)n1)S(=O)(=O)CC2.Cc1ccc(NC(=O)c2ccnc(C(F)(F)F)c2)cc1-c1cc(N2CCOCC2)c2nccn2c1.Cc1ccc(NC(=O)c2ccnc(C(F)F)c2)cc1-c1cc(N2CCOCC2)c2nccn2c1.Cc1ccc(NC(=O)c2ccnc(C(F)F)c2)cc1-c1cc(N2CCOCC2)c2nccn2n1.Cc1ccc(NC(=O)c2ccnc(S(C)(=O)=O)c2)cc1-c1cc(N2CCOCC2)c2nccn2c1.Cc1ccc(NC(=O)c2cnnc(C(F)(F)F)c2)cc1-c1cc(N2CCOCC2)c2nccn2c1
InChIInChI=1S/C29H29F3N4O2.C26H24F2N4O2.C25H22F3N5O2.C25H23F2N5O2.C25H24F2N4O4S.C25H25N5O4S.C24H21F3N6O2.C24H22F2N6O2/c1-3-4-20-6-7-21(15-25(20)29(30,31)32)28(37)34-23-8-5-19(2)24(17-23)22-16-26(35-11-13-38-14-12-35)27-33-9-10-36(27)18-22;1-17-5-6-21(30-26(33)19-4-2-3-18(13-19)24(27)28)15-22(17)20-14-23(31-9-11-34-12-10-31)25-29-7-8-32(25)16-20;1-16-2-3-19(31-24(34)17-4-5-29-22(13-17)25(26,27)28)14-20(16)18-12-21(32-8-10-35-11-9-32)23-30-6-7-33(23)15-18;1-16-2-3-19(30-25(33)17-4-5-28-21(12-17)23(26)27)14-20(16)18-13-22(31-8-10-34-11-9-31)24-29-6-7-32(24)15-18;1-15-5-6-18(28-25(32)17-4-2-3-16(13-17)22(26)27)14-19(15)23-29-20-7-12-36(33,34)21(20)24(30-23)31-8-10-35-11-9-31;1-17-3-4-20(28-25(31)18-5-6-26-23(14-18)35(2,32)33)15-21(17)19-13-22(29-9-11-34-12-10-29)24-27-7-8-30(24)16-19;1-15-2-3-18(30-23(34)16-11-21(24(25,26)27)31-29-13-16)12-19(15)17-10-20(32-6-8-35-9-7-32)22-28-4-5-33(22)14-17;1-15-2-3-17(29-24(33)16-4-5-27-20(12-16)22(25)26)13-18(15)19-14-21(31-8-10-34-11-9-31)23-28-6-7-32(23)30-19/h5-10,15-18H,3-4,11-14H2,1-2H3,(H,34,37);2-8,13-16,24H,9-12H2,1H3,(H,30,33);2-7,12-15H,8-11H2,1H3,(H,31,34);2-7,12-15,23H,8-11H2,1H3,(H,30,33);2-6,13-14,22H,7-12H2,1H3,(H,28,32);3-8,13-16H,9-12H2,1-2H3,(H,28,31);2-5,10-14H,6-9H2,1H3,(H,30,34);2-7,12-14,22H,8-11H2,1H3,(H,29,33)
InChIKeyAJFVGQULOWZFRJ-UHFFFAOYSA-N
XLogP36.59
TPSA637.95 Ų
H-Bond Donors8
H-Bond Acceptors51
Rotatable Bonds39
Heavy Atoms281
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5003883.11
LogP ≤ 536.59
H-Bond Donors ≤ 58
H-Bond Acceptors ≤ 1051

Analyze 3-(difluoromethyl)-N-[4-methyl-3-(4-morpholin-4-yl-5,5-dioxo-6,7-dihydrothieno[3,2-d]pyrimidin-2-yl)phenyl]benzamide;3-(difluoromethyl)-N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-a]pyridin-6-yl)phenyl]benzamide;2-(difluoromethyl)-N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-a]pyridin-6-yl)phenyl]pyridine-4-carboxamide;2-(difluoromethyl)-N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-b]pyridazin-6-yl)phenyl]pyridine-4-carboxamide;N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-a]pyridin-6-yl)phenyl]-2-methylsulfonylpyridine-4-carboxamide;N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-a]pyridin-6-yl)phenyl]-4-propyl-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-a]pyridin-6-yl)phenyl]-6-(trifluoromethyl)pyridazine-4-carboxamide;N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-a]pyridin-6-yl)phenyl]-2-(trifluoromethyl)pyridine-4-carboxamide with MolForge

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Related Compounds

6-morpholin-4-yl-N-[4-[4-[8-(pyridin-4-ylcarbamoyl)-2-[2-(trifluoromethyl)phenyl]imidazo[1,2-b]pyridazin-6-yl]morpholin-3-yl]-1,3-thiazol-2-yl]-2-[3-(trifluoromethyl)phenyl]imidazo[1,2-b]pyridazine-8-carboxamide
CID 123922375
N-[diethyl(oxo)-lambda6-sulfanylidene]-5-ethylsulfonyl-6-[3-methyl-6-(trifluoromethyl)imidazo[4,5-c]pyridin-2-yl]pyridine-3-carboxamide;N-(dimethyl-lambda4-sulfanylidene)-5-ethylsulfonyl-6-[3-methyl-6-(trifluoromethyl)imidazo[4,5-c]pyridin-2-yl]pyridine-3-carboxamide;N-[dimethyl(oxo)-lambda6-sulfanylidene]-5-ethylsulfonyl-6-[7-methyl-3-(trifluoromethyl)imidazo[4,5-c]pyridazin-6-yl]pyridine-3-carboxamide;N-[dimethyl(oxo)-lambda6-sulfanylidene]-5-ethylsulfonyl-6-[3-methyl-6-(trifluoromethyl)imidazo[4,5-c]pyridin-2-yl]pyridine-3-carboxamide;bis(N-[dimethyl(oxo)-lambda6-sulfanylidene]-5-ethylsulfonyl-6-[7-(trifluoromethyl)imidazo[1,2-c]pyrimidin-2-yl]pyridine-3-carboxamide);5-ethylsulfonyl-6-[3-methyl-6-(trifluoromethyl)imidazo[4,5-c]pyridin-2-yl]-N-(4-oxo-1,4-oxathian-4-ylidene)pyridine-3-carboxamide
CID 157286462
N-[diethyl(oxo)-lambda6-sulfanylidene]-5-ethylsulfonyl-6-[3-methyl-6-(trifluoromethyl)imidazo[4,5-b]pyridin-2-yl]pyridine-3-carboxamide;N-[diethyl(oxo)-lambda6-sulfanylidene]-5-ethylsulfonyl-6-[7-methyl-3-(trifluoromethyl)imidazo[4,5-c]pyridazin-6-yl]pyridine-3-carboxamide;N-[dimethyl(oxo)-lambda6-sulfanylidene]-5-ethylsulfonyl-6-[7-(trifluoromethyl)imidazo[1,2-a]pyridin-2-yl]pyridine-3-carboxamide;N-(ethyl-methyl-oxo-lambda6-sulfanylidene)-5-ethylsulfonyl-6-[3-methyl-6-(trifluoromethyl)imidazo[4,5-b]pyridin-2-yl]pyridine-3-carboxamide;5-ethylsulfonyl-6-[3-methyl-6-(trifluoromethyl)imidazo[4,5-b]pyridin-2-yl]-N-(4-oxo-1,4-oxathian-4-ylidene)pyridine-3-carboxamide;5-ethylsulfonyl-6-[3-methyl-6-(trifluoromethyl)imidazo[4,5-b]pyridin-2-yl]-N-(1-oxothietan-1-ylidene)pyridine-3-carboxamide
CID 157322528
6-(2-cyanopropan-2-yl)-N-[6-methyl-5-(7-morpholin-4-ylpyrazolo[1,5-a]pyrimidin-5-yl)-3-pyridinyl]pyridazine-4-carboxamide;2-(difluoromethyl)-N-[4-methyl-3-(7-morpholin-4-ylpyrazolo[1,5-a]pyrimidin-5-yl)phenyl]pyridine-4-carboxamide;N-[4-methyl-3-[4-[(3R)-3-methylmorpholin-4-yl]-1H-imidazo[4,5-c]pyridin-6-yl]phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(7-morpholin-4-ylpyrazolo[1,5-a]pyrimidin-5-yl)phenyl]-2-methylsulfonylpyridine-4-carboxamide;N-[6-methyl-5-(7-morpholin-4-ylpyrazolo[1,5-a]pyrimidin-5-yl)-3-pyridinyl]-2-methylsulfonylpyridine-4-carboxamide;N-[6-methyl-5-(7-morpholin-4-ylpyrazolo[1,5-a]pyrimidin-5-yl)-3-pyridinyl]-4-(trifluoromethyl)pyridine-2-carboxamide
CID 157569446
(4R)-4-[3-(3-acetyl-4-fluorophenyl)-2-pyridinyl]-1-[4-(cyclopenten-1-yl)-3-(trifluoromethyl)-4H-pyrazol-1-ium-1-yl]-5-(3,5-difluorophenyl)pentan-2-one;(4R)-4-[3-(3-acetyl-4-fluorophenyl)-2-pyridinyl]-5-(3,5-difluorophenyl)-1-[3-(trifluoromethyl)-4,5,6,7-tetrahydropyrazolo[5,4-c]pyridin-1-yl]pentan-2-one;7-[(4R)-4-[3-(3-acetylphenyl)-2-pyridinyl]-5-(3,5-difluorophenyl)-2-oxopentyl]-3-methyl-1,5-dihydrocyclopenta[b]pyridin-2-one;(4R)-4-[3-[3-(cyclopropylmethylsulfonyl)phenyl]-2-pyridinyl]-5-(3,5-difluorophenyl)-1-(5,6-dimethylbenzimidazol-1-yl)pentan-2-one;(4R)-5-(3,5-difluorophenyl)-4-[5-(4-methylphenyl)pyrimidin-4-yl]-1-[3-(trifluoromethyl)-4,5,6,7-tetrahydroindazol-1-yl]pentan-2-one
CID 157646883
1,3-dimethyl-N-[6-methyl-5-(4-morpholin-4-yl-1H-imidazo[4,5-c]pyridin-6-yl)-3-pyridinyl]pyrazole-4-carboxamide;1-ethyl-3-methyl-N-[6-methyl-5-(4-morpholin-4-yl-1H-imidazo[4,5-c]pyridin-6-yl)-3-pyridinyl]pyrazole-4-carboxamide;N-[4-methyl-3-[4-[(3R)-3-methylmorpholin-4-yl]-1H-imidazo[4,5-c]pyridin-6-yl]phenyl]-3-(trifluoromethyl)benzamide;N-[6-methyl-5-(7-morpholin-4-yl-3H-benzimidazol-5-yl)-3-pyridinyl]-3-methylsulfonylbenzamide;N-[4-methyl-3-(4-morpholin-4-yl-1H-imidazo[4,5-c]pyridin-6-yl)phenyl]-3-(trifluoromethyl)benzamide;N-[6-methyl-5-(7-morpholin-4-ylpyrazolo[1,5-a]pyrimidin-5-yl)-3-pyridinyl]-4-(trifluoromethyl)pyridine-2-carboxamide
CID 157659753
3-[4-(Azetidin-1-yl)-2-methylpyrimidin-5-yl]-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-(3-fluorophenyl)-3-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(4-methyl-2-morpholin-4-ylpyrimidin-5-yl)-8-thiophen-2-yl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-[4-methyl-2-(3-oxopiperazin-1-yl)pyrimidin-5-yl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-[2-(methylsulfonylmethyl)phenyl]-8-thiophen-2-yl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(6-methylsulfonyl-3-pyridinyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzamide;5-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyridine-2-carboxamide
CID 157965647
CID 158430034
CID 158430034
2-(4-cyclopentylanilino)-6-(2-methyl-4-thiophen-3-ylphenyl)-8-phenylpyrido[2,3-d]pyrimidin-7-one;8-[2-(dimethylamino)ethyl]-6-[5-methyl-1-(2-methyl-1,2,4-triazol-3-yl)imidazol-4-yl]-2-[4-piperazin-1-yl-3-(trifluoromethyl)anilino]pyrido[2,3-d]pyrimidin-7-one;2-[4-[(3R,5S)-3,5-dimethylpiperazin-1-yl]-3-fluoroanilino]-6-[1-methyl-4-(2-methyltriazol-4-yl)imidazol-2-yl]-8-(oxolan-3-yl)pyrido[2,3-d]pyrimidin-7-one;6-(3-methyl-5-thiophen-3-yl-2-pyridinyl)-2-[4-(1,2,3,6-tetrahydropyridin-4-yl)anilino]-8-(2,2,2-trifluoroethyl)pyrido[2,3-d]pyrimidin-7-one
CID 158457455
3-anilino-N-[5-[6-(morpholin-4-ylmethyl)-1H-benzimidazol-2-yl]-1H-pyrazol-4-yl]pyridine-2-carboxamide;2-methyl-N-[5-[6-(morpholin-4-ylmethyl)-1H-benzimidazol-2-yl]-1H-pyrazol-4-yl]-4-(trifluoromethyl)-1,3-thiazole-5-carboxamide;N-[5-[6-(morpholin-4-ylmethyl)-1H-benzimidazol-2-yl]-1H-pyrazol-4-yl]-2-phenylbenzamide;N-[5-[6-(morpholin-4-ylmethyl)-1H-benzimidazol-2-yl]-1H-pyrazol-4-yl]-2-(2-phenylethyl)benzamide;N-[5-[6-(morpholin-4-ylmethyl)-1H-benzimidazol-2-yl]-1H-pyrazol-4-yl]-1-pyrimidin-2-ylpiperidine-4-carboxamide
CID 158570745
1,3-dimethyl-N-[6-methyl-5-(4-morpholin-4-yl-1H-imidazo[4,5-c]pyridin-6-yl)-3-pyridinyl]pyrazole-4-carboxamide;2,5-dimethyl-N-[6-methyl-5-(4-morpholin-4-yl-1H-imidazo[4,5-c]pyridin-6-yl)-3-pyridinyl]pyrazole-3-carboxamide;1-ethyl-3-methyl-N-[6-methyl-5-(4-morpholin-4-yl-1H-imidazo[4,5-c]pyridin-6-yl)-3-pyridinyl]pyrazole-4-carboxamide;3-methyl-N-[6-methyl-5-(4-morpholin-4-yl-1H-imidazo[4,5-c]pyridin-6-yl)-3-pyridinyl]-1-propan-2-ylpyrazole-4-carboxamide;N-[6-methyl-5-(7-morpholin-4-yl-3H-benzimidazol-5-yl)-3-pyridinyl]-3-methylsulfonylbenzamide;N-[4-methyl-3-(4-morpholin-4-yl-1H-imidazo[4,5-c]pyridin-6-yl)phenyl]-3-(trifluoromethyl)benzamide
CID 158658190
6-[4-[C-(2-aminoethenyl)-N-methylcarbonimidoyl]-1-methylimidazol-2-yl]-2-(4-cyclohexylanilino)-8-(2-morpholin-4-ylethyl)pyrido[2,3-d]pyrimidin-7-one;6-[2-(1-amino-3-methyliminoprop-1-en-2-yl)pyrimidin-5-yl]-8-(2-oxo-2-pyrrolidin-1-ylethyl)-2-(4-piperidin-4-ylanilino)pyrido[2,3-d]pyrimidin-7-one;2-(4-cyclopentylanilino)-6-(4-pyridazin-4-ylphenyl)-8-(1,3-thiazol-2-ylmethyl)pyrido[2,3-d]pyrimidin-7-one;6-[5-methyl-1-(3-methylimidazol-4-yl)imidazol-4-yl]-8-[2-[methyl(methylsulfanyl)amino]ethyl]-2-[4-(1-methylpyrrolidin-3-yl)anilino]pyrido[2,3-d]pyrimidin-7-one;6-[2-methyl-4-(1-methylimidazol-2-yl)phenyl]-2-(4-piperazin-1-ylanilino)-8-[[2-(trifluoromethyl)phenyl]methyl]pyrido[2,3-d]pyrimidin-7-one;6-[5-(1-methylpyrrol-2-yl)-2-pyridinyl]-8-(oxan-4-ylmethyl)-2-[4-(1,2,3,6-tetrahydropyridin-4-yl)anilino]pyrido[2,3-d]pyrimidin-7-one;dihydrate
CID 158803126

Frequently Asked Questions

What is the IUPAC name of 3-(difluoromethyl)-N-[4-methyl-3-(4-morpholin-4-yl-5,5-dioxo-6,7-dihydrothieno[3,2-d]pyrimidin-2-yl)phenyl]benzamide;3-(difluoromethyl)-N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-a]pyridin-6-yl)phenyl]benzamide;2-(difluoromethyl)-N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-a]pyridin-6-yl)phenyl]pyridine-4-carboxamide;2-(difluoromethyl)-N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-b]pyridazin-6-yl)phenyl]pyridine-4-carboxamide;N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-a]pyridin-6-yl)phenyl]-2-methylsulfonylpyridine-4-carboxamide;N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-a]pyridin-6-yl)phenyl]-4-propyl-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-a]pyridin-6-yl)phenyl]-6-(trifluoromethyl)pyridazine-4-carboxamide;N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-a]pyridin-6-yl)phenyl]-2-(trifluoromethyl)pyridine-4-carboxamide?
The IUPAC name of 3-(difluoromethyl)-N-[4-methyl-3-(4-morpholin-4-yl-5,5-dioxo-6,7-dihydrothieno[3,2-d]pyrimidin-2-yl)phenyl]benzamide;3-(difluoromethyl)-N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-a]pyridin-6-yl)phenyl]benzamide;2-(difluoromethyl)-N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-a]pyridin-6-yl)phenyl]pyridine-4-carboxamide;2-(difluoromethyl)-N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-b]pyridazin-6-yl)phenyl]pyridine-4-carboxamide;N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-a]pyridin-6-yl)phenyl]-2-methylsulfonylpyridine-4-carboxamide;N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-a]pyridin-6-yl)phenyl]-4-propyl-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-a]pyridin-6-yl)phenyl]-6-(trifluoromethyl)pyridazine-4-carboxamide;N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-a]pyridin-6-yl)phenyl]-2-(trifluoromethyl)pyridine-4-carboxamide (CID 157132519) is 3-(difluoromethyl)-N-[4-methyl-3-(4-morpholin-4-yl-5,5-dioxo-6,7-dihydrothieno[3,2-d]pyrimidin-2-yl)phenyl]benzamide;3-(difluoromethyl)-N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-a]pyridin-6-yl)phenyl]benzamide;2-(difluoromethyl)-N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-a]pyridin-6-yl)phenyl]pyridine-4-carboxamide;2-(difluoromethyl)-N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-b]pyridazin-6-yl)phenyl]pyridine-4-carboxamide;N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-a]pyridin-6-yl)phenyl]-2-methylsulfonylpyridine-4-carboxamide;N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-a]pyridin-6-yl)phenyl]-4-propyl-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-a]pyridin-6-yl)phenyl]-6-(trifluoromethyl)pyridazine-4-carboxamide;N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-a]pyridin-6-yl)phenyl]-2-(trifluoromethyl)pyridine-4-carboxamide.
What is the SMILES notation for 3-(difluoromethyl)-N-[4-methyl-3-(4-morpholin-4-yl-5,5-dioxo-6,7-dihydrothieno[3,2-d]pyrimidin-2-yl)phenyl]benzamide;3-(difluoromethyl)-N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-a]pyridin-6-yl)phenyl]benzamide;2-(difluoromethyl)-N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-a]pyridin-6-yl)phenyl]pyridine-4-carboxamide;2-(difluoromethyl)-N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-b]pyridazin-6-yl)phenyl]pyridine-4-carboxamide;N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-a]pyridin-6-yl)phenyl]-2-methylsulfonylpyridine-4-carboxamide;N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-a]pyridin-6-yl)phenyl]-4-propyl-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-a]pyridin-6-yl)phenyl]-6-(trifluoromethyl)pyridazine-4-carboxamide;N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-a]pyridin-6-yl)phenyl]-2-(trifluoromethyl)pyridine-4-carboxamide?
The canonical SMILES for 3-(difluoromethyl)-N-[4-methyl-3-(4-morpholin-4-yl-5,5-dioxo-6,7-dihydrothieno[3,2-d]pyrimidin-2-yl)phenyl]benzamide;3-(difluoromethyl)-N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-a]pyridin-6-yl)phenyl]benzamide;2-(difluoromethyl)-N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-a]pyridin-6-yl)phenyl]pyridine-4-carboxamide;2-(difluoromethyl)-N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-b]pyridazin-6-yl)phenyl]pyridine-4-carboxamide;N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-a]pyridin-6-yl)phenyl]-2-methylsulfonylpyridine-4-carboxamide;N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-a]pyridin-6-yl)phenyl]-4-propyl-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-a]pyridin-6-yl)phenyl]-6-(trifluoromethyl)pyridazine-4-carboxamide;N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-a]pyridin-6-yl)phenyl]-2-(trifluoromethyl)pyridine-4-carboxamide is CCCc1ccc(C(=O)Nc2ccc(C)c(-c3cc(N4CCOCC4)c4nccn4c3)c2)cc1C(F)(F)F.Cc1ccc(NC(=O)c2cccc(C(F)F)c2)cc1-c1cc(N2CCOCC2)c2nccn2c1.Cc1ccc(NC(=O)c2cccc(C(F)F)c2)cc1-c1nc2c(c(N3CCOCC3)n1)S(=O)(=O)CC2.Cc1ccc(NC(=O)c2ccnc(C(F)(F)F)c2)cc1-c1cc(N2CCOCC2)c2nccn2c1.Cc1ccc(NC(=O)c2ccnc(C(F)F)c2)cc1-c1cc(N2CCOCC2)c2nccn2c1.Cc1ccc(NC(=O)c2ccnc(C(F)F)c2)cc1-c1cc(N2CCOCC2)c2nccn2n1.Cc1ccc(NC(=O)c2ccnc(S(C)(=O)=O)c2)cc1-c1cc(N2CCOCC2)c2nccn2c1.Cc1ccc(NC(=O)c2cnnc(C(F)(F)F)c2)cc1-c1cc(N2CCOCC2)c2nccn2c1.
What is the InChIKey of 3-(difluoromethyl)-N-[4-methyl-3-(4-morpholin-4-yl-5,5-dioxo-6,7-dihydrothieno[3,2-d]pyrimidin-2-yl)phenyl]benzamide;3-(difluoromethyl)-N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-a]pyridin-6-yl)phenyl]benzamide;2-(difluoromethyl)-N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-a]pyridin-6-yl)phenyl]pyridine-4-carboxamide;2-(difluoromethyl)-N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-b]pyridazin-6-yl)phenyl]pyridine-4-carboxamide;N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-a]pyridin-6-yl)phenyl]-2-methylsulfonylpyridine-4-carboxamide;N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-a]pyridin-6-yl)phenyl]-4-propyl-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-a]pyridin-6-yl)phenyl]-6-(trifluoromethyl)pyridazine-4-carboxamide;N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-a]pyridin-6-yl)phenyl]-2-(trifluoromethyl)pyridine-4-carboxamide?
The InChIKey is AJFVGQULOWZFRJ-UHFFFAOYSA-N. The full InChI is InChI=1S/C29H29F3N4O2.C26H24F2N4O2.C25H22F3N5O2.C25H23F2N5O2.C25H24F2N4O4S.C25H25N5O4S.C24H21F3N6O2.C24H22F2N6O2/c1-3-4-20-6-7-21(15-25(20)29(30,31)32)28(37)34-23-8-5-19(2)24(17-23)22-16-26(35-11-13-38-14-12-35)27-33-9-10-36(27)18-22;1-17-5-6-21(30-26(33)19-4-2-3-18(13-19)24(27)28)15-22(17)20-14-23(31-9-11-34-12-10-31)25-29-7-8-32(25)16-20;1-16-2-3-19(31-24(34)17-4-5-29-22(13-17)25(26,27)28)14-20(16)18-12-21(32-8-10-35-11-9-32)23-30-6-7-33(23)15-18;1-16-2-3-19(30-25(33)17-4-5-28-21(12-17)23(26)27)14-20(16)18-13-22(31-8-10-34-11-9-31)24-29-6-7-32(24)15-18;1-15-5-6-18(28-25(32)17-4-2-3-16(13-17)22(26)27)14-19(15)23-29-20-7-12-36(33,34)21(20)24(30-23)31-8-10-35-11-9-31;1-17-3-4-20(28-25(31)18-5-6-26-23(14-18)35(2,32)33)15-21(17)19-13-22(29-9-11-34-12-10-29)24-27-7-8-30(24)16-19;1-15-2-3-18(30-23(34)16-11-21(24(25,26)27)31-29-13-16)12-19(15)17-10-20(32-6-8-35-9-7-32)22-28-4-5-33(22)14-17;1-15-2-3-17(29-24(33)16-4-5-27-20(12-16)22(25)26)13-18(15)19-14-21(31-8-10-34-11-9-31)23-28-6-7-32(23)30-19/h5-10,15-18H,3-4,11-14H2,1-2H3,(H,34,37);2-8,13-16,24H,9-12H2,1H3,(H,30,33);2-7,12-15H,8-11H2,1H3,(H,31,34);2-7,12-15,23H,8-11H2,1H3,(H,30,33);2-6,13-14,22H,7-12H2,1H3,(H,28,32);3-8,13-16H,9-12H2,1-2H3,(H,28,31);2-5,10-14H,6-9H2,1H3,(H,30,34);2-7,12-14,22H,8-11H2,1H3,(H,29,33).
What are the key properties of 3-(difluoromethyl)-N-[4-methyl-3-(4-morpholin-4-yl-5,5-dioxo-6,7-dihydrothieno[3,2-d]pyrimidin-2-yl)phenyl]benzamide;3-(difluoromethyl)-N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-a]pyridin-6-yl)phenyl]benzamide;2-(difluoromethyl)-N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-a]pyridin-6-yl)phenyl]pyridine-4-carboxamide;2-(difluoromethyl)-N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-b]pyridazin-6-yl)phenyl]pyridine-4-carboxamide;N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-a]pyridin-6-yl)phenyl]-2-methylsulfonylpyridine-4-carboxamide;N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-a]pyridin-6-yl)phenyl]-4-propyl-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-a]pyridin-6-yl)phenyl]-6-(trifluoromethyl)pyridazine-4-carboxamide;N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-a]pyridin-6-yl)phenyl]-2-(trifluoromethyl)pyridine-4-carboxamide?
3-(difluoromethyl)-N-[4-methyl-3-(4-morpholin-4-yl-5,5-dioxo-6,7-dihydrothieno[3,2-d]pyrimidin-2-yl)phenyl]benzamide;3-(difluoromethyl)-N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-a]pyridin-6-yl)phenyl]benzamide;2-(difluoromethyl)-N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-a]pyridin-6-yl)phenyl]pyridine-4-carboxamide;2-(difluoromethyl)-N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-b]pyridazin-6-yl)phenyl]pyridine-4-carboxamide;N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-a]pyridin-6-yl)phenyl]-2-methylsulfonylpyridine-4-carboxamide;N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-a]pyridin-6-yl)phenyl]-4-propyl-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-a]pyridin-6-yl)phenyl]-6-(trifluoromethyl)pyridazine-4-carboxamide;N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-a]pyridin-6-yl)phenyl]-2-(trifluoromethyl)pyridine-4-carboxamide has a molecular weight of 3883.11 g/mol, XLogP of 36.59, 39 rotatable bonds, 8 hydrogen bond donors, and 51 hydrogen bond acceptors.
Where does this data come from?
All data for 3-(difluoromethyl)-N-[4-methyl-3-(4-morpholin-4-yl-5,5-dioxo-6,7-dihydrothieno[3,2-d]pyrimidin-2-yl)phenyl]benzamide;3-(difluoromethyl)-N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-a]pyridin-6-yl)phenyl]benzamide;2-(difluoromethyl)-N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-a]pyridin-6-yl)phenyl]pyridine-4-carboxamide;2-(difluoromethyl)-N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-b]pyridazin-6-yl)phenyl]pyridine-4-carboxamide;N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-a]pyridin-6-yl)phenyl]-2-methylsulfonylpyridine-4-carboxamide;N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-a]pyridin-6-yl)phenyl]-4-propyl-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-a]pyridin-6-yl)phenyl]-6-(trifluoromethyl)pyridazine-4-carboxamide;N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-a]pyridin-6-yl)phenyl]-2-(trifluoromethyl)pyridine-4-carboxamide is sourced from PubChem (CID 157132519), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).