5-chloro-3-[3-[2-[(3R)-3-hydroxy-1-methyl-2-oxopyrrolidin-3-yl]ethynyl]phenyl]-7H-cyclopenta[c]pyridine-1-carboxamide;8-[3-[2-[(3R)-3-hydroxy-1-methyl-2-methylidenepyrrolidin-3-yl]ethynyl]phenyl]-2-methylimidazo[1,2-a]pyrazine-6-carboxamide;8-[3-[2-[(3R)-3-hydroxy-1-methyl-2-methylidenepyrrolidin-3-yl]ethynyl]phenyl]-3-methylimidazo[1,2-a]pyrazine-6-carboxamide;6-[5-[2-[(3R)-3-hydroxy-1-methyl-2-oxopyrrolidin-3-yl]ethynyl]-2,3-dihydro-1-benzofuran-7-yl]pyridine-2-carboxamide;4-[3-[2-[(3R)-3-hydroxy-1-methyl-2-oxopyrrolidin-3-yl]ethynyl]phenyl]-1-methylpyrazolo[4,3-c]pyridine-6-carboxamide;8-[3-[2-[(3R)-3-hydroxy-1-methyl-2-oxopyrrolidin-3-yl]ethynyl]phenyl]-1,7-naphthyridine-6-carboxamide

C130H116ClN25O17 — CID 157136159

IUPAC5-chloro-3-[3-[2-[(3R)-3-hydroxy-1-methyl-2-oxopyrrolidin-3-yl]ethynyl]phenyl]-7H-cyclopenta[c]pyridine-1-carboxamide;8-[3-[2-[(3R)-3-hydroxy-1-methyl-2-methylidenepyrrolidin-3-yl]ethynyl]phenyl]-2-methylimidazo[1,2-a]pyrazine-6-carboxamide;8-[3-[2-[(3R)-3-hydroxy-1-methyl-2-methylidenepyrrolidin-3-yl]ethynyl]phenyl]-3-methylimidazo[1,2-a]pyrazine-6-carboxamide;6-[5-[2-[(3R)-3-hydroxy-1-methyl-2-oxopyrrolidin-3-yl]ethynyl]-2,3-dihydro-1-benzofuran-7-yl]pyridine-2-carboxamide;4-[3-[2-[(3R)-3-hydroxy-1-methyl-2-oxopyrrolidin-3-yl]ethynyl]phenyl]-1-methylpyrazolo[4,3-c]pyridine-6-carboxamide;8-[3-[2-[(3R)-3-hydroxy-1-methyl-2-oxopyrrolidin-3-yl]ethynyl]phenyl]-1,7-naphthyridine-6-carboxamide
SMILESC=C1N(C)CC[C@@]1(O)C#Cc1cccc(-c2nc(C(N)=O)cn3c(C)cnc23)c1.C=C1N(C)CC[C@@]1(O)C#Cc1cccc(-c2nc(C(N)=O)cn3cc(C)nc23)c1.CN1CC[C@@](O)(C#Cc2cc3c(c(-c4cccc(C(N)=O)n4)c2)OCC3)C1=O.CN1CC[C@@](O)(C#Cc2cccc(-c3cc4c(c(C(N)=O)n3)CC=C4Cl)c2)C1=O.CN1CC[C@@](O)(C#Cc2cccc(-c3nc(C(N)=O)cc4c3cnn4C)c2)C1=O.CN1CC[C@@](O)(C#Cc2cccc(-c3nc(C(N)=O)cc4cccnc34)c2)C1=O
InChIInChI=1S/C22H18ClN3O3.2C22H21N5O2.C22H18N4O3.C21H19N5O3.C21H19N3O4/c1-26-10-9-22(29,21(26)28)8-7-13-3-2-4-14(11-13)18-12-16-15(5-6-17(16)23)19(25-18)20(24)27;1-14-12-27-13-18(20(23)28)25-19(21(27)24-14)17-6-4-5-16(11-17)7-8-22(29)9-10-26(3)15(22)2;1-14-12-24-21-19(25-18(20(23)28)13-27(14)21)17-6-4-5-16(11-17)7-8-22(29)9-10-26(3)15(22)2;1-26-11-9-22(29,21(26)28)8-7-14-4-2-5-15(12-14)19-18-16(6-3-10-24-18)13-17(25-19)20(23)27;1-25-9-8-21(29,20(25)28)7-6-13-4-3-5-14(10-13)18-15-12-23-26(2)17(15)11-16(24-18)19(22)27;1-24-9-8-21(27,20(24)26)7-5-13-11-14-6-10-28-18(14)15(12-13)16-3-2-4-17(23-16)19(22)25/h2-4,6,11-12,29H,5,9-10H2,1H3,(H2,24,27);2*4-6,11-13,29H,2,9-10H2,1,3H3,(H2,23,28);2-6,10,12-13,29H,9,11H2,1H3,(H2,23,27);3-5,10-12,29H,8-9H2,1-2H3,(H2,22,27);2-4,11-12,27H,6,8-10H2,1H3,(H2,22,25)/t4*22-;2*21-/m000000/s1
InChIKeyAJQJZHXJVMYMSD-JIJWZFSFSA-N
MW2335.97 g/mol
LogP8.15
Rot. Bonds12

About 5-chloro-3-[3-[2-[(3R)-3-hydroxy-1-methyl-2-oxopyrrolidin-3-yl]ethynyl]phenyl]-7H-cyclopenta[c]pyridine-1-carboxamide;8-[3-[2-[(3R)-3-hydroxy-1-methyl-2-methylidenepyrrolidin-3-yl]ethynyl]phenyl]-2-methylimidazo[1,2-a]pyrazine-6-carboxamide;8-[3-[2-[(3R)-3-hydroxy-1-methyl-2-methylidenepyrrolidin-3-yl]ethynyl]phenyl]-3-methylimidazo[1,2-a]pyrazine-6-carboxamide;6-[5-[2-[(3R)-3-hydroxy-1-methyl-2-oxopyrrolidin-3-yl]ethynyl]-2,3-dihydro-1-benzofuran-7-yl]pyridine-2-carboxamide;4-[3-[2-[(3R)-3-hydroxy-1-methyl-2-oxopyrrolidin-3-yl]ethynyl]phenyl]-1-methylpyrazolo[4,3-c]pyridine-6-carboxamide;8-[3-[2-[(3R)-3-hydroxy-1-methyl-2-oxopyrrolidin-3-yl]ethynyl]phenyl]-1,7-naphthyridine-6-carboxamide

5-chloro-3-[3-[2-[(3R)-3-hydroxy-1-methyl-2-oxopyrrolidin-3-yl]ethynyl]phenyl]-7H-cyclopenta[c]pyridine-1-carboxamide;8-[3-[2-[(3R)-3-hydroxy-1-methyl-2-methylidenepyrrolidin-3-yl]ethynyl]phenyl]-2-methylimidazo[1,2-a]pyrazine-6-carboxamide;8-[3-[2-[(3R)-3-hydroxy-1-methyl-2-methylidenepyrrolidin-3-yl]ethynyl]phenyl]-3-methylimidazo[1,2-a]pyrazine-6-carboxamide;6-[5-[2-[(3R)-3-hydroxy-1-methyl-2-oxopyrrolidin-3-yl]ethynyl]-2,3-dihydro-1-benzofuran-7-yl]pyridine-2-carboxamide;4-[3-[2-[(3R)-3-hydroxy-1-methyl-2-oxopyrrolidin-3-yl]ethynyl]phenyl]-1-methylpyrazolo[4,3-c]pyridine-6-carboxamide;8-[3-[2-[(3R)-3-hydroxy-1-methyl-2-oxopyrrolidin-3-yl]ethynyl]phenyl]-1,7-naphthyridine-6-carboxamide (PubChem CID 157136159) has the molecular formula C130H116ClN25O17 and a molecular weight of 2335.97 g/mol. Its IUPAC name is 5-chloro-3-[3-[2-[(3R)-3-hydroxy-1-methyl-2-oxopyrrolidin-3-yl]ethynyl]phenyl]-7H-cyclopenta[c]pyridine-1-carboxamide;8-[3-[2-[(3R)-3-hydroxy-1-methyl-2-methylidenepyrrolidin-3-yl]ethynyl]phenyl]-2-methylimidazo[1,2-a]pyrazine-6-carboxamide;8-[3-[2-[(3R)-3-hydroxy-1-methyl-2-methylidenepyrrolidin-3-yl]ethynyl]phenyl]-3-methylimidazo[1,2-a]pyrazine-6-carboxamide;6-[5-[2-[(3R)-3-hydroxy-1-methyl-2-oxopyrrolidin-3-yl]ethynyl]-2,3-dihydro-1-benzofuran-7-yl]pyridine-2-carboxamide;4-[3-[2-[(3R)-3-hydroxy-1-methyl-2-oxopyrrolidin-3-yl]ethynyl]phenyl]-1-methylpyrazolo[4,3-c]pyridine-6-carboxamide;8-[3-[2-[(3R)-3-hydroxy-1-methyl-2-oxopyrrolidin-3-yl]ethynyl]phenyl]-1,7-naphthyridine-6-carboxamide.

Molecular Properties

Compound Name5-chloro-3-[3-[2-[(3R)-3-hydroxy-1-methyl-2-oxopyrrolidin-3-yl]ethynyl]phenyl]-7H-cyclopenta[c]pyridine-1-carboxamide;8-[3-[2-[(3R)-3-hydroxy-1-methyl-2-methylidenepyrrolidin-3-yl]ethynyl]phenyl]-2-methylimidazo[1,2-a]pyrazine-6-carboxamide;8-[3-[2-[(3R)-3-hydroxy-1-methyl-2-methylidenepyrrolidin-3-yl]ethynyl]phenyl]-3-methylimidazo[1,2-a]pyrazine-6-carboxamide;6-[5-[2-[(3R)-3-hydroxy-1-methyl-2-oxopyrrolidin-3-yl]ethynyl]-2,3-dihydro-1-benzofuran-7-yl]pyridine-2-carboxamide;4-[3-[2-[(3R)-3-hydroxy-1-methyl-2-oxopyrrolidin-3-yl]ethynyl]phenyl]-1-methylpyrazolo[4,3-c]pyridine-6-carboxamide;8-[3-[2-[(3R)-3-hydroxy-1-methyl-2-oxopyrrolidin-3-yl]ethynyl]phenyl]-1,7-naphthyridine-6-carboxamide
PubChem CID157136159
Molecular FormulaC130H116ClN25O17
Molecular Weight2335.97 g/mol
Exact Mass2333.87
IUPAC Name5-chloro-3-[3-[2-[(3R)-3-hydroxy-1-methyl-2-oxopyrrolidin-3-yl]ethynyl]phenyl]-7H-cyclopenta[c]pyridine-1-carboxamide;8-[3-[2-[(3R)-3-hydroxy-1-methyl-2-methylidenepyrrolidin-3-yl]ethynyl]phenyl]-2-methylimidazo[1,2-a]pyrazine-6-carboxamide;8-[3-[2-[(3R)-3-hydroxy-1-methyl-2-methylidenepyrrolidin-3-yl]ethynyl]phenyl]-3-methylimidazo[1,2-a]pyrazine-6-carboxamide;6-[5-[2-[(3R)-3-hydroxy-1-methyl-2-oxopyrrolidin-3-yl]ethynyl]-2,3-dihydro-1-benzofuran-7-yl]pyridine-2-carboxamide;4-[3-[2-[(3R)-3-hydroxy-1-methyl-2-oxopyrrolidin-3-yl]ethynyl]phenyl]-1-methylpyrazolo[4,3-c]pyridine-6-carboxamide;8-[3-[2-[(3R)-3-hydroxy-1-methyl-2-oxopyrrolidin-3-yl]ethynyl]phenyl]-1,7-naphthyridine-6-carboxamide
SMILESC=C1N(C)CC[C@@]1(O)C#Cc1cccc(-c2nc(C(N)=O)cn3c(C)cnc23)c1.C=C1N(C)CC[C@@]1(O)C#Cc1cccc(-c2nc(C(N)=O)cn3cc(C)nc23)c1.CN1CC[C@@](O)(C#Cc2cc3c(c(-c4cccc(C(N)=O)n4)c2)OCC3)C1=O.CN1CC[C@@](O)(C#Cc2cccc(-c3cc4c(c(C(N)=O)n3)CC=C4Cl)c2)C1=O.CN1CC[C@@](O)(C#Cc2cccc(-c3nc(C(N)=O)cc4c3cnn4C)c2)C1=O.CN1CC[C@@](O)(C#Cc2cccc(-c3nc(C(N)=O)cc4cccnc34)c2)C1=O
InChIInChI=1S/C22H18ClN3O3.2C22H21N5O2.C22H18N4O3.C21H19N5O3.C21H19N3O4/c1-26-10-9-22(29,21(26)28)8-7-13-3-2-4-14(11-13)18-12-16-15(5-6-17(16)23)19(25-18)20(24)27;1-14-12-27-13-18(20(23)28)25-19(21(27)24-14)17-6-4-5-16(11-17)7-8-22(29)9-10-26(3)15(22)2;1-14-12-24-21-19(25-18(20(23)28)13-27(14)21)17-6-4-5-16(11-17)7-8-22(29)9-10-26(3)15(22)2;1-26-11-9-22(29,21(26)28)8-7-14-4-2-5-15(12-14)19-18-16(6-3-10-24-18)13-17(25-19)20(23)27;1-25-9-8-21(29,20(25)28)7-6-13-4-3-5-14(10-13)18-15-12-23-26(2)17(15)11-16(24-18)19(22)27;1-24-9-8-21(27,20(24)26)7-5-13-11-14-6-10-28-18(14)15(12-13)16-3-2-4-17(23-16)19(22)25/h2-4,6,11-12,29H,5,9-10H2,1H3,(H2,24,27);2*4-6,11-13,29H,2,9-10H2,1,3H3,(H2,23,28);2-6,10,12-13,29H,9,11H2,1H3,(H2,23,27);3-5,10-12,29H,8-9H2,1-2H3,(H2,22,27);2-4,11-12,27H,6,8-10H2,1H3,(H2,22,25)/t4*22-;2*21-/m000000/s1
InChIKeyAJQJZHXJVMYMSD-JIJWZFSFSA-N
XLogP8.15
TPSA619.52 Ų
H-Bond Donors12
H-Bond Acceptors32
Rotatable Bonds12
Heavy Atoms173
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5002335.97
LogP ≤ 58.15
H-Bond Donors ≤ 512
H-Bond Acceptors ≤ 1032

Computed Properties (RDKit)

Structural Alerts{'alert_name': 'triple_bond', 'substructure': 'N/A'}

Analyze 5-chloro-3-[3-[2-[(3R)-3-hydroxy-1-methyl-2-oxopyrrolidin-3-yl]ethynyl]phenyl]-7H-cyclopenta[c]pyridine-1-carboxamide;8-[3-[2-[(3R)-3-hydroxy-1-methyl-2-methylidenepyrrolidin-3-yl]ethynyl]phenyl]-2-methylimidazo[1,2-a]pyrazine-6-carboxamide;8-[3-[2-[(3R)-3-hydroxy-1-methyl-2-methylidenepyrrolidin-3-yl]ethynyl]phenyl]-3-methylimidazo[1,2-a]pyrazine-6-carboxamide;6-[5-[2-[(3R)-3-hydroxy-1-methyl-2-oxopyrrolidin-3-yl]ethynyl]-2,3-dihydro-1-benzofuran-7-yl]pyridine-2-carboxamide;4-[3-[2-[(3R)-3-hydroxy-1-methyl-2-oxopyrrolidin-3-yl]ethynyl]phenyl]-1-methylpyrazolo[4,3-c]pyridine-6-carboxamide;8-[3-[2-[(3R)-3-hydroxy-1-methyl-2-oxopyrrolidin-3-yl]ethynyl]phenyl]-1,7-naphthyridine-6-carboxamide with MolForge

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Related Compounds

2-[4-[[(3R)-3-(dimethylamino)pyrrolidin-1-yl]methyl]-3-(trifluoromethyl)phenyl]-1-[3-(2-imidazo[1,2-a]pyrazin-3-ylethynyl)-4-methylphenyl]ethanone;4-[[(3R)-3-hydroxypyrrolidin-1-yl]methyl]-N-[2-(2-imidazo[1,2-b]pyridazin-3-ylethynyl)-4-pyridinyl]-3-(trifluoromethyl)benzamide;1-[3-(2-imidazo[1,2-a]pyridin-3-ylethynyl)-4-methylphenyl]-2-[4-(2-pyrrolidin-1-ylethoxy)-3-(trifluoromethyl)phenyl]ethanone;1-[3-(2-imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methylphenyl]-2-[4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]ethanone
CID 157572711
1-cyclopropyl-6-[3-[2-[(3R)-3-hydroxy-1-methyl-2-oxopyrrolidin-3-yl]ethynyl]phenyl]pyrazolo[3,4-d]pyrimidine-4-carboxamide;6-[2,4-difluoro-5-[2-[(3R)-3-hydroxy-1-methyl-2-methylidenepyrrolidin-3-yl]ethynyl]phenyl]-4-methoxypyridine-2-carboxamide;3-(difluoromethyl)-6-[3-[2-[(3R)-3-hydroxy-1-methyl-2-oxopyrrolidin-3-yl]ethynyl]phenyl]pyridine-2-carboxamide;5-(difluoromethyl)-6-[3-[2-[(3R)-3-hydroxy-1-methyl-2-oxopyrrolidin-3-yl]ethynyl]phenyl]pyridine-2-carboxamide;4-(4-fluoropyrazol-1-yl)-6-[3-[2-[(3R)-3-hydroxy-1-methyl-2-methylidenepyrrolidin-3-yl]ethynyl]phenyl]pyridine-2-carboxamide;6-[3-[2-[(3R)-3-hydroxy-1-methyl-2-methylidenepyrrolidin-3-yl]ethynyl]phenyl]-4-(2,2,2-trifluoroethoxy)pyridine-2-carboxamide;2-[3-[2-[(3R)-3-hydroxy-1-methyl-2-oxopyrrolidin-3-yl]ethynyl]phenyl]-7-methyl-5,6-dihydropyrrolo[2,3-d]pyrimidine-4-carboxamide
CID 157723290
3-amino-6-[2,3-difluoro-5-[2-[(3R)-3-hydroxy-1-methyl-2-oxopyrrolidin-3-yl]ethynyl]phenyl]pyridine-2-carboxamide;1-cyclopropyl-6-[3-[2-[(3R)-3-hydroxy-1-methyl-2-oxopyrrolidin-3-yl]ethynyl]phenyl]pyrazolo[3,4-d]pyrimidine-4-carboxamide;6-[2,4-difluoro-5-[2-[(3R)-3-hydroxy-1-methyl-2-methylidenepyrrolidin-3-yl]ethynyl]phenyl]-4-methoxypyridine-2-carboxamide;4-(4-fluoropyrazol-1-yl)-6-[3-[2-[(3R)-3-hydroxy-1-methyl-2-methylidenepyrrolidin-3-yl]ethynyl]phenyl]pyridine-2-carboxamide;3-hydroxy-6-[3-[2-[(3R)-3-hydroxy-1-methyl-2-oxopyrrolidin-3-yl]ethynyl]phenyl]-4-methylpyridine-2-carboxamide;6-[3-[2-[(3R)-3-hydroxy-1-methyl-2-methylidenepyrrolidin-3-yl]ethynyl]phenyl]-4-(2,2,2-trifluoroethoxy)pyridine-2-carboxamide;2-[3-[2-[(3R)-3-hydroxy-1-methyl-2-oxopyrrolidin-3-yl]ethynyl]phenyl]-7-methyl-5,6-dihydropyrrolo[2,3-d]pyrimidine-4-carboxamide
CID 157774780
1-cyclopropyl-6-[3-[2-[(3R)-3-hydroxy-1-methyl-2-oxopyrrolidin-3-yl]ethynyl]phenyl]pyrazolo[3,4-d]pyrimidine-4-carboxamide;6-[2,4-difluoro-5-[2-[(3R)-3-hydroxy-1-methyl-2-methylidenepyrrolidin-3-yl]ethynyl]phenyl]-4-methoxypyridine-2-carboxamide;3-(difluoromethyl)-6-[3-[2-[(3R)-3-hydroxy-1-methyl-2-oxopyrrolidin-3-yl]ethynyl]phenyl]pyridine-2-carboxamide;5-(difluoromethyl)-6-[3-[2-[(3R)-3-hydroxy-1-methyl-2-oxopyrrolidin-3-yl]ethynyl]phenyl]pyridine-2-carboxamide;4-(4-fluoropyrazol-1-yl)-6-[3-[2-[(3R)-3-hydroxy-1-methyl-2-methylidenepyrrolidin-3-yl]ethynyl]phenyl]pyridine-2-carboxamide;6-[3-[2-[(3R)-3-hydroxy-1-methyl-2-methylidenepyrrolidin-3-yl]ethynyl]phenyl]-4-(2,2,2-trifluoroethoxy)pyridine-2-carboxamide;2-[3-[2-[(3R)-3-hydroxy-1-methyl-2-oxopyrrolidin-3-yl]ethynyl]phenyl]-7-methyl-5,6-dihydropyrrolo[2,3-d]pyrimidine-4-carboxamide;methane
CID 159349338
2-[4-[[(3R)-3-(dimethylamino)pyrrolidin-1-yl]methyl]-3-(trifluoromethyl)phenyl]-1-[3-(2-imidazo[1,2-a]pyrazin-3-ylethynyl)-4-methylphenyl]ethanone;4-[[(3R)-3-hydroxypyrrolidin-1-yl]methyl]-N-[2-(2-imidazo[1,2-a]pyridin-3-ylethynyl)-4-pyridinyl]-3-(trifluoromethyl)benzamide;1-[3-(2-imidazo[1,2-a]pyridin-3-ylethynyl)-4-methylphenyl]-2-[4-(2-pyrrolidin-1-ylethoxy)-3-(trifluoromethyl)phenyl]ethanone;1-[3-(2-imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methylphenyl]-2-[4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]ethanone
CID 159405610
3,21-Dimethyl-14-aza-21-azoniapentacyclo[12.7.0.02,7.08,13.015,20]henicosa-1(21),2,4,6,8,10,12,15,17,19-decaene;3,21-dimethyl-6,14-diaza-21-azoniapentacyclo[12.7.0.02,7.08,13.015,20]henicosa-1(21),2,4,6,8,10,12,15,17,19-decaene;1,12-dimethylimidazo[1,2-f]phenanthridin-1-ium;ethane;1-methyl-2-(2-methylphenyl)-3-phenylbenzimidazol-1-ium;1-methyl-2-(2-methylphenyl)-3-phenylimidazol-1-ium;2-methyl-1-(2-methylphenyl)pyrazol-2-ium;7-methyl-6-(1-methylpyridin-1-ium-2-yl)-[1]benzofuro[3,2-b]pyridine;7-methyl-8-(1-methylpyridin-1-ium-2-yl)-[1]benzofuro[2,3-b]pyridine;7-methyl-6-(1-methylpyridin-1-ium-2-yl)-[1]benzofuro[3,2-c]pyridine;7-methyl-8-(1-methylpyridin-1-ium-2-yl)-[1]benzofuro[2,3-c]pyridine
CID 157215754
N-[[3-[(2-fluorophenyl)methoxy]phenyl]methyl]imidazo[1,5-a]pyridine-5-carboxamide;N-[[3-[(2-fluorophenyl)methoxy]phenyl]methyl]-2-imidazo[1,2-a]pyridin-2-ylacetamide;N-[[3-[(2-fluorophenyl)methoxy]phenyl]methyl]-N-[(2R)-1-methoxypropan-2-yl]imidazo[1,2-a]pyridine-2-carboxamide;N-[[3-[(2-fluorophenyl)methoxy]phenyl]methyl]-N-[(2S)-1-methoxypropan-2-yl]imidazo[1,2-a]pyridine-2-carboxamide;N-[[3-[2-(2-fluorophenyl)propan-2-yloxy]phenyl]methyl]-[1,2,4]triazolo[4,3-a]pyridine-8-carboxamide
CID 157433933
6-[[6-(4-acetylpyrazol-1-yl)pyrimidin-4-yl]amino]-2-(2-hydroxyethyl)-8-methyl-2,7-naphthyridin-1-one;1-[1-[6-chloro-2-[(4-methylphenyl)methylamino]pyrimidin-4-yl]-5-ethylpyrazol-4-yl]ethanone;3-[4-(2,5-diazabicyclo[2.2.1]heptan-2-yl)pyrazol-1-yl]-N-(1-phenylethyl)aniline;2-(5,6-dimethyl-1,3-dihydroisoindol-2-yl)-N-[4-(4-ethylpyrazol-1-yl)-3-pyridinyl]pyrimidine-4-carboxamide;2-(2-hydroxyethyl)-8-methyl-6-[[6-(4-methylpyrazol-1-yl)pyrimidin-4-yl]amino]-2,7-naphthyridin-1-one;N-[(3-methylidene-4H-chromen-6-yl)methyl]-6-[4-(4-methylphenyl)pyrazol-1-yl]pyrimidine-4-carboxamide;N-[4-[4-(1-methylimino-2,3-dihydroinden-5-yl)-3-pyridin-4-ylpyrazol-1-yl]-2-pyridinyl]prop-2-enamide;sulfane
CID 158210056
3-amino-6-[5-[2-[(3S)-1,3-dimethyl-2-oxopyrrolidin-3-yl]ethynyl]-2,3-difluorophenyl]pyridine-2-carboxamide;1-cyclopropyl-6-[3-[2-[(3R)-3-hydroxy-1-methyl-2-oxopyrrolidin-3-yl]ethynyl]phenyl]pyrazolo[3,4-d]pyrimidine-4-carboxamide;6-[2,4-difluoro-5-[2-[(3R)-3-hydroxy-1-methyl-2-methylidenepyrrolidin-3-yl]ethynyl]phenyl]-4-methoxypyridine-2-carboxamide;4-(4-fluoropyrazol-1-yl)-6-[3-[2-[(3R)-3-hydroxy-1-methyl-2-methylidenepyrrolidin-3-yl]ethynyl]phenyl]pyridine-2-carboxamide;2-[3-[2-[(3R)-3-hydroxy-1-methyl-2-oxopyrrolidin-3-yl]ethynyl]phenyl]-7-methyl-5,6-dihydropyrrolo[2,3-d]pyrimidine-4-carboxamide
CID 158253582
3-amino-5-fluoro-6-[3-fluoro-5-[2-[(3R)-3-hydroxy-1-methyl-2-oxopyrrolidin-3-yl]ethynyl]phenyl]pyridine-2-carboxamide;4-(difluoromethoxy)-6-[3-[2-[(3R)-3-hydroxy-1-methyl-2-oxopyrrolidin-3-yl]ethynyl]phenyl]pyridine-2-carboxamide;8-[3-fluoro-5-[2-[(3R)-3-hydroxy-1-methyl-2-methylidenepyrrolidin-3-yl]ethynyl]phenyl]imidazo[1,2-a]pyrazine-6-carboxamide;6-[4-fluoro-3-[2-[(3R)-3-hydroxy-1-methyl-2-methylidenepyrrolidin-3-yl]ethynyl]phenyl]-4-methylpyridine-2-carboxamide;6-[3-[2-[(3R)-3-hydroxy-1-methyl-2-methylidenepyrrolidin-3-yl]ethynyl]phenyl]-3-methylpyrazine-2-carboxamide;2-[3-[2-[(3R)-3-hydroxy-1-methyl-2-methylidenepyrrolidin-3-yl]ethynyl]phenyl]-6-(3-methylpyrazol-1-yl)pyrimidine-4-carboxamide;6-[3-[2-[(3R)-3-hydroxy-1-methyl-2-methylidenepyrrolidin-3-yl]ethynyl]phenyl]-4-(oxetan-3-ylamino)pyridine-2-carboxamide
CID 158267195
Ethyl 6-[2-(6-methyl-2-pyridinyl)phenyl]imidazo[1,2-a]pyridine-3-carboxylate;3-methyl-6-[2-(6-methyl-2-pyridinyl)phenyl]imidazo[1,2-a]pyridine;6-[2-(3-methylpyrazol-1-yl)phenyl]imidazo[1,2-a]pyridine-3-carboxamide;5-[2-(6-methyl-2-pyridinyl)phenyl]-1-benzofuran-3-carboxamide;methyl 5-(2-pyridin-2-ylphenyl)pyrazolo[1,5-a]pyridine-3-carboxylate;5-[2-(6-methyl-2-pyridinyl)phenyl]pyrazolo[1,5-a]pyridine-3-carboxylic acid
CID 158331535
5-amino-2-[2-fluoro-5-[2-[(3R)-3-hydroxy-1-methyl-2-oxopyrrolidin-3-yl]ethynyl]phenyl]pyrimidine-4-carboxamide;5-amino-8-[3-[2-[(3R)-3-hydroxy-1-methyl-2-methylidenepyrrolidin-3-yl]ethynyl]phenyl]imidazo[1,2-a]pyrazine-6-carboxamide;5-amino-2-[3-[2-[(3R)-3-hydroxy-1-methyl-2-oxopyrrolidin-3-yl]ethynyl]phenyl]-6-(2-methoxyethoxy)pyrimidine-4-carboxamide;5-amino-2-[3-[2-[(3R)-3-hydroxy-1-methyl-2-oxopyrrolidin-3-yl]ethynyl]phenyl]-6-(oxan-4-yloxy)pyrimidine-4-carboxamide;2-[3-[2-[(3S)-1,3-dimethyl-2-oxopyrrolidin-3-yl]ethynyl]-4-fluorophenyl]-6-(5-methylpyrazol-1-yl)pyrimidine-4-carboxamide;2-[2-fluoro-5-[2-[(3R)-3-hydroxy-1-methyl-2-oxopyrrolidin-3-yl]ethynyl]phenyl]-5-(3-methoxypropyl)pyrimidine-4-carboxamide
CID 158423546

Frequently Asked Questions

What is the IUPAC name of 5-chloro-3-[3-[2-[(3R)-3-hydroxy-1-methyl-2-oxopyrrolidin-3-yl]ethynyl]phenyl]-7H-cyclopenta[c]pyridine-1-carboxamide;8-[3-[2-[(3R)-3-hydroxy-1-methyl-2-methylidenepyrrolidin-3-yl]ethynyl]phenyl]-2-methylimidazo[1,2-a]pyrazine-6-carboxamide;8-[3-[2-[(3R)-3-hydroxy-1-methyl-2-methylidenepyrrolidin-3-yl]ethynyl]phenyl]-3-methylimidazo[1,2-a]pyrazine-6-carboxamide;6-[5-[2-[(3R)-3-hydroxy-1-methyl-2-oxopyrrolidin-3-yl]ethynyl]-2,3-dihydro-1-benzofuran-7-yl]pyridine-2-carboxamide;4-[3-[2-[(3R)-3-hydroxy-1-methyl-2-oxopyrrolidin-3-yl]ethynyl]phenyl]-1-methylpyrazolo[4,3-c]pyridine-6-carboxamide;8-[3-[2-[(3R)-3-hydroxy-1-methyl-2-oxopyrrolidin-3-yl]ethynyl]phenyl]-1,7-naphthyridine-6-carboxamide?
The IUPAC name of 5-chloro-3-[3-[2-[(3R)-3-hydroxy-1-methyl-2-oxopyrrolidin-3-yl]ethynyl]phenyl]-7H-cyclopenta[c]pyridine-1-carboxamide;8-[3-[2-[(3R)-3-hydroxy-1-methyl-2-methylidenepyrrolidin-3-yl]ethynyl]phenyl]-2-methylimidazo[1,2-a]pyrazine-6-carboxamide;8-[3-[2-[(3R)-3-hydroxy-1-methyl-2-methylidenepyrrolidin-3-yl]ethynyl]phenyl]-3-methylimidazo[1,2-a]pyrazine-6-carboxamide;6-[5-[2-[(3R)-3-hydroxy-1-methyl-2-oxopyrrolidin-3-yl]ethynyl]-2,3-dihydro-1-benzofuran-7-yl]pyridine-2-carboxamide;4-[3-[2-[(3R)-3-hydroxy-1-methyl-2-oxopyrrolidin-3-yl]ethynyl]phenyl]-1-methylpyrazolo[4,3-c]pyridine-6-carboxamide;8-[3-[2-[(3R)-3-hydroxy-1-methyl-2-oxopyrrolidin-3-yl]ethynyl]phenyl]-1,7-naphthyridine-6-carboxamide (CID 157136159) is 5-chloro-3-[3-[2-[(3R)-3-hydroxy-1-methyl-2-oxopyrrolidin-3-yl]ethynyl]phenyl]-7H-cyclopenta[c]pyridine-1-carboxamide;8-[3-[2-[(3R)-3-hydroxy-1-methyl-2-methylidenepyrrolidin-3-yl]ethynyl]phenyl]-2-methylimidazo[1,2-a]pyrazine-6-carboxamide;8-[3-[2-[(3R)-3-hydroxy-1-methyl-2-methylidenepyrrolidin-3-yl]ethynyl]phenyl]-3-methylimidazo[1,2-a]pyrazine-6-carboxamide;6-[5-[2-[(3R)-3-hydroxy-1-methyl-2-oxopyrrolidin-3-yl]ethynyl]-2,3-dihydro-1-benzofuran-7-yl]pyridine-2-carboxamide;4-[3-[2-[(3R)-3-hydroxy-1-methyl-2-oxopyrrolidin-3-yl]ethynyl]phenyl]-1-methylpyrazolo[4,3-c]pyridine-6-carboxamide;8-[3-[2-[(3R)-3-hydroxy-1-methyl-2-oxopyrrolidin-3-yl]ethynyl]phenyl]-1,7-naphthyridine-6-carboxamide.
What is the SMILES notation for 5-chloro-3-[3-[2-[(3R)-3-hydroxy-1-methyl-2-oxopyrrolidin-3-yl]ethynyl]phenyl]-7H-cyclopenta[c]pyridine-1-carboxamide;8-[3-[2-[(3R)-3-hydroxy-1-methyl-2-methylidenepyrrolidin-3-yl]ethynyl]phenyl]-2-methylimidazo[1,2-a]pyrazine-6-carboxamide;8-[3-[2-[(3R)-3-hydroxy-1-methyl-2-methylidenepyrrolidin-3-yl]ethynyl]phenyl]-3-methylimidazo[1,2-a]pyrazine-6-carboxamide;6-[5-[2-[(3R)-3-hydroxy-1-methyl-2-oxopyrrolidin-3-yl]ethynyl]-2,3-dihydro-1-benzofuran-7-yl]pyridine-2-carboxamide;4-[3-[2-[(3R)-3-hydroxy-1-methyl-2-oxopyrrolidin-3-yl]ethynyl]phenyl]-1-methylpyrazolo[4,3-c]pyridine-6-carboxamide;8-[3-[2-[(3R)-3-hydroxy-1-methyl-2-oxopyrrolidin-3-yl]ethynyl]phenyl]-1,7-naphthyridine-6-carboxamide?
The canonical SMILES for 5-chloro-3-[3-[2-[(3R)-3-hydroxy-1-methyl-2-oxopyrrolidin-3-yl]ethynyl]phenyl]-7H-cyclopenta[c]pyridine-1-carboxamide;8-[3-[2-[(3R)-3-hydroxy-1-methyl-2-methylidenepyrrolidin-3-yl]ethynyl]phenyl]-2-methylimidazo[1,2-a]pyrazine-6-carboxamide;8-[3-[2-[(3R)-3-hydroxy-1-methyl-2-methylidenepyrrolidin-3-yl]ethynyl]phenyl]-3-methylimidazo[1,2-a]pyrazine-6-carboxamide;6-[5-[2-[(3R)-3-hydroxy-1-methyl-2-oxopyrrolidin-3-yl]ethynyl]-2,3-dihydro-1-benzofuran-7-yl]pyridine-2-carboxamide;4-[3-[2-[(3R)-3-hydroxy-1-methyl-2-oxopyrrolidin-3-yl]ethynyl]phenyl]-1-methylpyrazolo[4,3-c]pyridine-6-carboxamide;8-[3-[2-[(3R)-3-hydroxy-1-methyl-2-oxopyrrolidin-3-yl]ethynyl]phenyl]-1,7-naphthyridine-6-carboxamide is C=C1N(C)CC[C@@]1(O)C#Cc1cccc(-c2nc(C(N)=O)cn3c(C)cnc23)c1.C=C1N(C)CC[C@@]1(O)C#Cc1cccc(-c2nc(C(N)=O)cn3cc(C)nc23)c1.CN1CC[C@@](O)(C#Cc2cc3c(c(-c4cccc(C(N)=O)n4)c2)OCC3)C1=O.CN1CC[C@@](O)(C#Cc2cccc(-c3cc4c(c(C(N)=O)n3)CC=C4Cl)c2)C1=O.CN1CC[C@@](O)(C#Cc2cccc(-c3nc(C(N)=O)cc4c3cnn4C)c2)C1=O.CN1CC[C@@](O)(C#Cc2cccc(-c3nc(C(N)=O)cc4cccnc34)c2)C1=O.
What is the InChIKey of 5-chloro-3-[3-[2-[(3R)-3-hydroxy-1-methyl-2-oxopyrrolidin-3-yl]ethynyl]phenyl]-7H-cyclopenta[c]pyridine-1-carboxamide;8-[3-[2-[(3R)-3-hydroxy-1-methyl-2-methylidenepyrrolidin-3-yl]ethynyl]phenyl]-2-methylimidazo[1,2-a]pyrazine-6-carboxamide;8-[3-[2-[(3R)-3-hydroxy-1-methyl-2-methylidenepyrrolidin-3-yl]ethynyl]phenyl]-3-methylimidazo[1,2-a]pyrazine-6-carboxamide;6-[5-[2-[(3R)-3-hydroxy-1-methyl-2-oxopyrrolidin-3-yl]ethynyl]-2,3-dihydro-1-benzofuran-7-yl]pyridine-2-carboxamide;4-[3-[2-[(3R)-3-hydroxy-1-methyl-2-oxopyrrolidin-3-yl]ethynyl]phenyl]-1-methylpyrazolo[4,3-c]pyridine-6-carboxamide;8-[3-[2-[(3R)-3-hydroxy-1-methyl-2-oxopyrrolidin-3-yl]ethynyl]phenyl]-1,7-naphthyridine-6-carboxamide?
The InChIKey is AJQJZHXJVMYMSD-JIJWZFSFSA-N. The full InChI is InChI=1S/C22H18ClN3O3.2C22H21N5O2.C22H18N4O3.C21H19N5O3.C21H19N3O4/c1-26-10-9-22(29,21(26)28)8-7-13-3-2-4-14(11-13)18-12-16-15(5-6-17(16)23)19(25-18)20(24)27;1-14-12-27-13-18(20(23)28)25-19(21(27)24-14)17-6-4-5-16(11-17)7-8-22(29)9-10-26(3)15(22)2;1-14-12-24-21-19(25-18(20(23)28)13-27(14)21)17-6-4-5-16(11-17)7-8-22(29)9-10-26(3)15(22)2;1-26-11-9-22(29,21(26)28)8-7-14-4-2-5-15(12-14)19-18-16(6-3-10-24-18)13-17(25-19)20(23)27;1-25-9-8-21(29,20(25)28)7-6-13-4-3-5-14(10-13)18-15-12-23-26(2)17(15)11-16(24-18)19(22)27;1-24-9-8-21(27,20(24)26)7-5-13-11-14-6-10-28-18(14)15(12-13)16-3-2-4-17(23-16)19(22)25/h2-4,6,11-12,29H,5,9-10H2,1H3,(H2,24,27);2*4-6,11-13,29H,2,9-10H2,1,3H3,(H2,23,28);2-6,10,12-13,29H,9,11H2,1H3,(H2,23,27);3-5,10-12,29H,8-9H2,1-2H3,(H2,22,27);2-4,11-12,27H,6,8-10H2,1H3,(H2,22,25)/t4*22-;2*21-/m000000/s1.
What are the key properties of 5-chloro-3-[3-[2-[(3R)-3-hydroxy-1-methyl-2-oxopyrrolidin-3-yl]ethynyl]phenyl]-7H-cyclopenta[c]pyridine-1-carboxamide;8-[3-[2-[(3R)-3-hydroxy-1-methyl-2-methylidenepyrrolidin-3-yl]ethynyl]phenyl]-2-methylimidazo[1,2-a]pyrazine-6-carboxamide;8-[3-[2-[(3R)-3-hydroxy-1-methyl-2-methylidenepyrrolidin-3-yl]ethynyl]phenyl]-3-methylimidazo[1,2-a]pyrazine-6-carboxamide;6-[5-[2-[(3R)-3-hydroxy-1-methyl-2-oxopyrrolidin-3-yl]ethynyl]-2,3-dihydro-1-benzofuran-7-yl]pyridine-2-carboxamide;4-[3-[2-[(3R)-3-hydroxy-1-methyl-2-oxopyrrolidin-3-yl]ethynyl]phenyl]-1-methylpyrazolo[4,3-c]pyridine-6-carboxamide;8-[3-[2-[(3R)-3-hydroxy-1-methyl-2-oxopyrrolidin-3-yl]ethynyl]phenyl]-1,7-naphthyridine-6-carboxamide?
5-chloro-3-[3-[2-[(3R)-3-hydroxy-1-methyl-2-oxopyrrolidin-3-yl]ethynyl]phenyl]-7H-cyclopenta[c]pyridine-1-carboxamide;8-[3-[2-[(3R)-3-hydroxy-1-methyl-2-methylidenepyrrolidin-3-yl]ethynyl]phenyl]-2-methylimidazo[1,2-a]pyrazine-6-carboxamide;8-[3-[2-[(3R)-3-hydroxy-1-methyl-2-methylidenepyrrolidin-3-yl]ethynyl]phenyl]-3-methylimidazo[1,2-a]pyrazine-6-carboxamide;6-[5-[2-[(3R)-3-hydroxy-1-methyl-2-oxopyrrolidin-3-yl]ethynyl]-2,3-dihydro-1-benzofuran-7-yl]pyridine-2-carboxamide;4-[3-[2-[(3R)-3-hydroxy-1-methyl-2-oxopyrrolidin-3-yl]ethynyl]phenyl]-1-methylpyrazolo[4,3-c]pyridine-6-carboxamide;8-[3-[2-[(3R)-3-hydroxy-1-methyl-2-oxopyrrolidin-3-yl]ethynyl]phenyl]-1,7-naphthyridine-6-carboxamide has a molecular weight of 2335.97 g/mol, XLogP of 8.15, 12 rotatable bonds, 12 hydrogen bond donors, and 32 hydrogen bond acceptors.
Where does this data come from?
All data for 5-chloro-3-[3-[2-[(3R)-3-hydroxy-1-methyl-2-oxopyrrolidin-3-yl]ethynyl]phenyl]-7H-cyclopenta[c]pyridine-1-carboxamide;8-[3-[2-[(3R)-3-hydroxy-1-methyl-2-methylidenepyrrolidin-3-yl]ethynyl]phenyl]-2-methylimidazo[1,2-a]pyrazine-6-carboxamide;8-[3-[2-[(3R)-3-hydroxy-1-methyl-2-methylidenepyrrolidin-3-yl]ethynyl]phenyl]-3-methylimidazo[1,2-a]pyrazine-6-carboxamide;6-[5-[2-[(3R)-3-hydroxy-1-methyl-2-oxopyrrolidin-3-yl]ethynyl]-2,3-dihydro-1-benzofuran-7-yl]pyridine-2-carboxamide;4-[3-[2-[(3R)-3-hydroxy-1-methyl-2-oxopyrrolidin-3-yl]ethynyl]phenyl]-1-methylpyrazolo[4,3-c]pyridine-6-carboxamide;8-[3-[2-[(3R)-3-hydroxy-1-methyl-2-oxopyrrolidin-3-yl]ethynyl]phenyl]-1,7-naphthyridine-6-carboxamide is sourced from PubChem (CID 157136159), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).