1-[4-(4-tert-butyl-1,3-thiazol-2-yl)-1-methylpyrazol-5-yl]-2-(2-phenyl-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-7-yl)ethanone;1-[4-[4-(difluoromethyl)-1,3-thiazol-2-yl]-1-methylpyrazol-5-yl]-2-[2-(4-fluorophenyl)-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-7-yl]ethanone;2-[2-(4-fluorophenyl)-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-7-yl]-1-[1-methyl-4-(4-methyl-1,3-thiazol-2-yl)pyrazol-5-yl]ethanone;2-(6-fluoro-2-phenyl-[1,2,4]triazolo[1,5-a]pyridin-7-yl)-1-[1-methyl-4-(3-methyl-2-pyridinyl)pyrazol-5-yl]ethanone;1-[1-methyl-4-(1,3-thiazol-2-yl)pyrazol-5-yl]-2-(2-phenyl-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-7-yl)ethanone

C118H111F5N26O5S4 — CID 157137454

About 1-[4-(4-tert-butyl-1,3-thiazol-2-yl)-1-methylpyrazol-5-yl]-2-(2-phenyl-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-7-yl)ethanone;1-[4-[4-(difluoromethyl)-1,3-thiazol-2-yl]-1-methylpyrazol-5-yl]-2-[2-(4-fluorophenyl)-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-7-yl]ethanone;2-[2-(4-fluorophenyl)-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-7-yl]-1-[1-methyl-4-(4-methyl-1,3-thiazol-2-yl)pyrazol-5-yl]ethanone;2-(6-fluoro-2-phenyl-[1,2,4]triazolo[1,5-a]pyridin-7-yl)-1-[1-methyl-4-(3-methyl-2-pyridinyl)pyrazol-5-yl]ethanone;1-[1-methyl-4-(1,3-thiazol-2-yl)pyrazol-5-yl]-2-(2-phenyl-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-7-yl)ethanone

1-[4-(4-tert-butyl-1,3-thiazol-2-yl)-1-methylpyrazol-5-yl]-2-(2-phenyl-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-7-yl)ethanone;1-[4-[4-(difluoromethyl)-1,3-thiazol-2-yl]-1-methylpyrazol-5-yl]-2-[2-(4-fluorophenyl)-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-7-yl]ethanone;2-[2-(4-fluorophenyl)-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-7-yl]-1-[1-methyl-4-(4-methyl-1,3-thiazol-2-yl)pyrazol-5-yl]ethanone;2-(6-fluoro-2-phenyl-[1,2,4]triazolo[1,5-a]pyridin-7-yl)-1-[1-methyl-4-(3-methyl-2-pyridinyl)pyrazol-5-yl]ethanone;1-[1-methyl-4-(1,3-thiazol-2-yl)pyrazol-5-yl]-2-(2-phenyl-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-7-yl)ethanone (PubChem CID 157137454) has the molecular formula C118H111F5N26O5S4 and a molecular weight of 2196.62 g/mol. Its IUPAC name is 1-[4-(4-tert-butyl-1,3-thiazol-2-yl)-1-methylpyrazol-5-yl]-2-(2-phenyl-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-7-yl)ethanone;1-[4-[4-(difluoromethyl)-1,3-thiazol-2-yl]-1-methylpyrazol-5-yl]-2-[2-(4-fluorophenyl)-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-7-yl]ethanone;2-[2-(4-fluorophenyl)-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-7-yl]-1-[1-methyl-4-(4-methyl-1,3-thiazol-2-yl)pyrazol-5-yl]ethanone;2-(6-fluoro-2-phenyl-[1,2,4]triazolo[1,5-a]pyridin-7-yl)-1-[1-methyl-4-(3-methyl-2-pyridinyl)pyrazol-5-yl]ethanone;1-[1-methyl-4-(1,3-thiazol-2-yl)pyrazol-5-yl]-2-(2-phenyl-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-7-yl)ethanone.

Molecular Properties

• Compound Name: 1-[4-(4-tert-butyl-1,3-thiazol-2-yl)-1-methylpyrazol-5-yl]-2-(2-phenyl-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-7-yl)ethanone;1-[4-[4-(difluoromethyl)-1,3-thiazol-2-yl]-1-methylpyrazol-5-yl]-2-[2-(4-fluorophenyl)-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-7-yl]ethanone;2-[2-(4-fluorophenyl)-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-7-yl]-1-[1-methyl-4-(4-methyl-1,3-thiazol-2-yl)pyrazol-5-yl]ethanone;2-(6-fluoro-2-phenyl-[1,2,4]triazolo[1,5-a]pyridin-7-yl)-1-[1-methyl-4-(3-methyl-2-pyridinyl)pyrazol-5-yl]ethanone;1-[1-methyl-4-(1,3-thiazol-2-yl)pyrazol-5-yl]-2-(2-phenyl-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-7-yl)ethanone
• PubChem CID: 157137454
• Molecular Formula: C118H111F5N26O5S4
• Molecular Weight: 2196.62 g/mol
• Exact Mass: 2194.80
• IUPAC Name: 1-[4-(4-tert-butyl-1,3-thiazol-2-yl)-1-methylpyrazol-5-yl]-2-(2-phenyl-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-7-yl)ethanone;1-[4-[4-(difluoromethyl)-1,3-thiazol-2-yl]-1-methylpyrazol-5-yl]-2-[2-(4-fluorophenyl)-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-7-yl]ethanone;2-[2-(4-fluorophenyl)-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-7-yl]-1-[1-methyl-4-(4-methyl-1,3-thiazol-2-yl)pyrazol-5-yl]ethanone;2-(6-fluoro-2-phenyl-[1,2,4]triazolo[1,5-a]pyridin-7-yl)-1-[1-methyl-4-(3-methyl-2-pyridinyl)pyrazol-5-yl]ethanone;1-[1-methyl-4-(1,3-thiazol-2-yl)pyrazol-5-yl]-2-(2-phenyl-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-7-yl)ethanone
• SMILES: Cc1cccnc1-c1cnn(C)c1C(=O)Cc1cc2nc(-c3ccccc3)nn2cc1F.Cc1csc(-c2cnn(C)c2C(=O)CC2CCn3cc(-c4ccc(F)cc4)nc3C2)n1.Cn1ncc(-c2nc(C(C)(C)C)cs2)c1C(=O)CC1CCn2cc(-c3ccccc3)nc2C1.Cn1ncc(-c2nc(C(F)F)cs2)c1C(=O)CC1CCn2cc(-c3ccc(F)cc3)nc2C1.Cn1ncc(-c2nccs2)c1C(=O)CC1CCn2cc(-c3ccccc3)nc2C1
• InChI: InChI=1S/C26H29N5OS.C24H19FN6O.C23H20F3N5OS.C23H22FN5OS.C22H21N5OS/c1-26(2,3)22-16-33-25(29-22)19-14-27-30(4)24(19)21(32)12-17-10-11-31-15-20(28-23(31)13-17)18-8-6-5-7-9-18;1-15-7-6-10-26-22(15)18-13-27-30(2)23(18)20(32)11-17-12-21-28-24(16-8-4-3-5-9-16)29-31(21)14-19(17)25;1-30-21(16(10-27-30)23-29-18(12-33-23)22(25)26)19(32)8-13-6-7-31-11-17(28-20(31)9-13)14-2-4-15(24)5-3-14;1-14-13-31-23(26-14)18-11-25-28(2)22(18)20(30)9-15-7-8-29-12-19(27-21(29)10-15)16-3-5-17(24)6-4-16;1-26-21(17(13-24-26)22-23-8-10-29-22)19(28)11-15-7-9-27-14-18(25-20(27)12-15)16-5-3-2-4-6-16/h5-9,14-17H,10-13H2,1-4H3;3-10,12-14H,11H2,1-2H3;2-5,10-13,22H,6-9H2,1H3;3-6,11-13,15H,7-10H2,1-2H3;2-6,8,10,13-15H,7,9,11-12H2,1H3
• InChIKey: AJUCNLOHTMACLN-UHFFFAOYSA-N
• XLogP: 23.86
• TPSA: 340.37 Ų
• H-Bond Acceptors: 35
• Rotatable Bonds: 26
• Heavy Atoms: 158
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	2196.62
LogP ≤ 5	23.86
H-Bond Donors ≤ 5	0
H-Bond Acceptors ≤ 10	35

Frequently Asked Questions

What is the IUPAC name of 1-[4-(4-tert-butyl-1,3-thiazol-2-yl)-1-methylpyrazol-5-yl]-2-(2-phenyl-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-7-yl)ethanone;1-[4-[4-(difluoromethyl)-1,3-thiazol-2-yl]-1-methylpyrazol-5-yl]-2-[2-(4-fluorophenyl)-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-7-yl]ethanone;2-[2-(4-fluorophenyl)-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-7-yl]-1-[1-methyl-4-(4-methyl-1,3-thiazol-2-yl)pyrazol-5-yl]ethanone;2-(6-fluoro-2-phenyl-[1,2,4]triazolo[1,5-a]pyridin-7-yl)-1-[1-methyl-4-(3-methyl-2-pyridinyl)pyrazol-5-yl]ethanone;1-[1-methyl-4-(1,3-thiazol-2-yl)pyrazol-5-yl]-2-(2-phenyl-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-7-yl)ethanone?

The IUPAC name of 1-[4-(4-tert-butyl-1,3-thiazol-2-yl)-1-methylpyrazol-5-yl]-2-(2-phenyl-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-7-yl)ethanone;1-[4-[4-(difluoromethyl)-1,3-thiazol-2-yl]-1-methylpyrazol-5-yl]-2-[2-(4-fluorophenyl)-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-7-yl]ethanone;2-[2-(4-fluorophenyl)-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-7-yl]-1-[1-methyl-4-(4-methyl-1,3-thiazol-2-yl)pyrazol-5-yl]ethanone;2-(6-fluoro-2-phenyl-[1,2,4]triazolo[1,5-a]pyridin-7-yl)-1-[1-methyl-4-(3-methyl-2-pyridinyl)pyrazol-5-yl]ethanone;1-[1-methyl-4-(1,3-thiazol-2-yl)pyrazol-5-yl]-2-(2-phenyl-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-7-yl)ethanone (CID 157137454) is 1-[4-(4-tert-butyl-1,3-thiazol-2-yl)-1-methylpyrazol-5-yl]-2-(2-phenyl-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-7-yl)ethanone;1-[4-[4-(difluoromethyl)-1,3-thiazol-2-yl]-1-methylpyrazol-5-yl]-2-[2-(4-fluorophenyl)-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-7-yl]ethanone;2-[2-(4-fluorophenyl)-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-7-yl]-1-[1-methyl-4-(4-methyl-1,3-thiazol-2-yl)pyrazol-5-yl]ethanone;2-(6-fluoro-2-phenyl-[1,2,4]triazolo[1,5-a]pyridin-7-yl)-1-[1-methyl-4-(3-methyl-2-pyridinyl)pyrazol-5-yl]ethanone;1-[1-methyl-4-(1,3-thiazol-2-yl)pyrazol-5-yl]-2-(2-phenyl-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-7-yl)ethanone.

What is the SMILES notation for 1-[4-(4-tert-butyl-1,3-thiazol-2-yl)-1-methylpyrazol-5-yl]-2-(2-phenyl-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-7-yl)ethanone;1-[4-[4-(difluoromethyl)-1,3-thiazol-2-yl]-1-methylpyrazol-5-yl]-2-[2-(4-fluorophenyl)-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-7-yl]ethanone;2-[2-(4-fluorophenyl)-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-7-yl]-1-[1-methyl-4-(4-methyl-1,3-thiazol-2-yl)pyrazol-5-yl]ethanone;2-(6-fluoro-2-phenyl-[1,2,4]triazolo[1,5-a]pyridin-7-yl)-1-[1-methyl-4-(3-methyl-2-pyridinyl)pyrazol-5-yl]ethanone;1-[1-methyl-4-(1,3-thiazol-2-yl)pyrazol-5-yl]-2-(2-phenyl-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-7-yl)ethanone?

The canonical SMILES for 1-[4-(4-tert-butyl-1,3-thiazol-2-yl)-1-methylpyrazol-5-yl]-2-(2-phenyl-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-7-yl)ethanone;1-[4-[4-(difluoromethyl)-1,3-thiazol-2-yl]-1-methylpyrazol-5-yl]-2-[2-(4-fluorophenyl)-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-7-yl]ethanone;2-[2-(4-fluorophenyl)-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-7-yl]-1-[1-methyl-4-(4-methyl-1,3-thiazol-2-yl)pyrazol-5-yl]ethanone;2-(6-fluoro-2-phenyl-[1,2,4]triazolo[1,5-a]pyridin-7-yl)-1-[1-methyl-4-(3-methyl-2-pyridinyl)pyrazol-5-yl]ethanone;1-[1-methyl-4-(1,3-thiazol-2-yl)pyrazol-5-yl]-2-(2-phenyl-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-7-yl)ethanone is Cc1cccnc1-c1cnn(C)c1C(=O)Cc1cc2nc(-c3ccccc3)nn2cc1F.Cc1csc(-c2cnn(C)c2C(=O)CC2CCn3cc(-c4ccc(F)cc4)nc3C2)n1.Cn1ncc(-c2nc(C(C)(C)C)cs2)c1C(=O)CC1CCn2cc(-c3ccccc3)nc2C1.Cn1ncc(-c2nc(C(F)F)cs2)c1C(=O)CC1CCn2cc(-c3ccc(F)cc3)nc2C1.Cn1ncc(-c2nccs2)c1C(=O)CC1CCn2cc(-c3ccccc3)nc2C1.

What is the InChIKey of 1-[4-(4-tert-butyl-1,3-thiazol-2-yl)-1-methylpyrazol-5-yl]-2-(2-phenyl-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-7-yl)ethanone;1-[4-[4-(difluoromethyl)-1,3-thiazol-2-yl]-1-methylpyrazol-5-yl]-2-[2-(4-fluorophenyl)-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-7-yl]ethanone;2-[2-(4-fluorophenyl)-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-7-yl]-1-[1-methyl-4-(4-methyl-1,3-thiazol-2-yl)pyrazol-5-yl]ethanone;2-(6-fluoro-2-phenyl-[1,2,4]triazolo[1,5-a]pyridin-7-yl)-1-[1-methyl-4-(3-methyl-2-pyridinyl)pyrazol-5-yl]ethanone;1-[1-methyl-4-(1,3-thiazol-2-yl)pyrazol-5-yl]-2-(2-phenyl-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-7-yl)ethanone?

The InChIKey is AJUCNLOHTMACLN-UHFFFAOYSA-N. The full InChI is InChI=1S/C26H29N5OS.C24H19FN6O.C23H20F3N5OS.C23H22FN5OS.C22H21N5OS/c1-26(2,3)22-16-33-25(29-22)19-14-27-30(4)24(19)21(32)12-17-10-11-31-15-20(28-23(31)13-17)18-8-6-5-7-9-18;1-15-7-6-10-26-22(15)18-13-27-30(2)23(18)20(32)11-17-12-21-28-24(16-8-4-3-5-9-16)29-31(21)14-19(17)25;1-30-21(16(10-27-30)23-29-18(12-33-23)22(25)26)19(32)8-13-6-7-31-11-17(28-20(31)9-13)14-2-4-15(24)5-3-14;1-14-13-31-23(26-14)18-11-25-28(2)22(18)20(30)9-15-7-8-29-12-19(27-21(29)10-15)16-3-5-17(24)6-4-16;1-26-21(17(13-24-26)22-23-8-10-29-22)19(28)11-15-7-9-27-14-18(25-20(27)12-15)16-5-3-2-4-6-16/h5-9,14-17H,10-13H2,1-4H3;3-10,12-14H,11H2,1-2H3;2-5,10-13,22H,6-9H2,1H3;3-6,11-13,15H,7-10H2,1-2H3;2-6,8,10,13-15H,7,9,11-12H2,1H3.

What are the key properties of 1-[4-(4-tert-butyl-1,3-thiazol-2-yl)-1-methylpyrazol-5-yl]-2-(2-phenyl-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-7-yl)ethanone;1-[4-[4-(difluoromethyl)-1,3-thiazol-2-yl]-1-methylpyrazol-5-yl]-2-[2-(4-fluorophenyl)-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-7-yl]ethanone;2-[2-(4-fluorophenyl)-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-7-yl]-1-[1-methyl-4-(4-methyl-1,3-thiazol-2-yl)pyrazol-5-yl]ethanone;2-(6-fluoro-2-phenyl-[1,2,4]triazolo[1,5-a]pyridin-7-yl)-1-[1-methyl-4-(3-methyl-2-pyridinyl)pyrazol-5-yl]ethanone;1-[1-methyl-4-(1,3-thiazol-2-yl)pyrazol-5-yl]-2-(2-phenyl-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-7-yl)ethanone?

1-[4-(4-tert-butyl-1,3-thiazol-2-yl)-1-methylpyrazol-5-yl]-2-(2-phenyl-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-7-yl)ethanone;1-[4-[4-(difluoromethyl)-1,3-thiazol-2-yl]-1-methylpyrazol-5-yl]-2-[2-(4-fluorophenyl)-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-7-yl]ethanone;2-[2-(4-fluorophenyl)-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-7-yl]-1-[1-methyl-4-(4-methyl-1,3-thiazol-2-yl)pyrazol-5-yl]ethanone;2-(6-fluoro-2-phenyl-[1,2,4]triazolo[1,5-a]pyridin-7-yl)-1-[1-methyl-4-(3-methyl-2-pyridinyl)pyrazol-5-yl]ethanone;1-[1-methyl-4-(1,3-thiazol-2-yl)pyrazol-5-yl]-2-(2-phenyl-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-7-yl)ethanone has a molecular weight of 2196.62 g/mol, XLogP of 23.86, 26 rotatable bonds, 0 hydrogen bond donors, and 35 hydrogen bond acceptors.

Where does this data come from?

All data for 1-[4-(4-tert-butyl-1,3-thiazol-2-yl)-1-methylpyrazol-5-yl]-2-(2-phenyl-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-7-yl)ethanone;1-[4-[4-(difluoromethyl)-1,3-thiazol-2-yl]-1-methylpyrazol-5-yl]-2-[2-(4-fluorophenyl)-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-7-yl]ethanone;2-[2-(4-fluorophenyl)-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-7-yl]-1-[1-methyl-4-(4-methyl-1,3-thiazol-2-yl)pyrazol-5-yl]ethanone;2-(6-fluoro-2-phenyl-[1,2,4]triazolo[1,5-a]pyridin-7-yl)-1-[1-methyl-4-(3-methyl-2-pyridinyl)pyrazol-5-yl]ethanone;1-[1-methyl-4-(1,3-thiazol-2-yl)pyrazol-5-yl]-2-(2-phenyl-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-7-yl)ethanone is sourced from PubChem (CID 157137454), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).