2-(6-cyclopropyloxy-3-pyridinyl)-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;2-(6-cyclopropyl-3-pyridinyl)-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;2-[6-(1,1-difluoroethyl)-3-pyridinyl]-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;2-[6-(2,2-difluoropropoxy)-3-pyridinyl]-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-2-[6-(1-fluoroethoxy)-3-pyridinyl]-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-2-[6-(1-fluoroethyl)-3-pyridinyl]-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(6-methyl-3-pyridinyl)-1-benzofuran-3-carboxamide

C240H204F13N35O31S7 — CID 157151283

IUPAC2-(6-cyclopropyloxy-3-pyridinyl)-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;2-(6-cyclopropyl-3-pyridinyl)-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;2-[6-(1,1-difluoroethyl)-3-pyridinyl]-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;2-[6-(2,2-difluoropropoxy)-3-pyridinyl]-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-2-[6-(1-fluoroethoxy)-3-pyridinyl]-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-2-[6-(1-fluoroethyl)-3-pyridinyl]-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(6-methyl-3-pyridinyl)-1-benzofuran-3-carboxamide
SMILESCNC(=O)c1c(-c2ccc(C(C)(F)F)nc2)oc2cc(N(C)S(C)(=O)=O)c(-c3ccc4c(n3)-c3cc5c(F)cccc5n3CC4)cc12.CNC(=O)c1c(-c2ccc(C(C)F)nc2)oc2cc(N(C)S(C)(=O)=O)c(-c3ccc4c(n3)-c3cc5c(F)cccc5n3CC4)cc12.CNC(=O)c1c(-c2ccc(C)nc2)oc2cc(N(C)S(C)(=O)=O)c(-c3ccc4c(n3)-c3cc5c(F)cccc5n3CC4)cc12.CNC(=O)c1c(-c2ccc(C3CC3)nc2)oc2cc(N(C)S(C)(=O)=O)c(-c3ccc4c(n3)-c3cc5c(F)cccc5n3CC4)cc12.CNC(=O)c1c(-c2ccc(OC(C)F)nc2)oc2cc(N(C)S(C)(=O)=O)c(-c3ccc4c(n3)-c3cc5c(F)cccc5n3CC4)cc12.CNC(=O)c1c(-c2ccc(OC3CC3)nc2)oc2cc(N(C)S(C)(=O)=O)c(-c3ccc4c(n3)-c3cc5c(F)cccc5n3CC4)cc12.CNC(=O)c1c(-c2ccc(OCC(C)(F)F)nc2)oc2cc(N(C)S(C)(=O)=O)c(-c3ccc4c(n3)-c3cc5c(F)cccc5n3CC4)cc12
InChIInChI=1S/C35H30F3N5O5S.C35H30FN5O5S.C35H30FN5O4S.C34H28F3N5O4S.C34H29F2N5O5S.C34H29F2N5O4S.C33H28FN5O4S/c1-35(37,38)18-47-30-11-9-20(17-40-30)33-31(34(44)39-2)23-14-22(27(16-29(23)48-33)42(3)49(4,45)46)25-10-8-19-12-13-43-26-7-5-6-24(36)21(26)15-28(43)32(19)41-25;1-37-35(42)32-24-15-23(26-11-7-19-13-14-41-27-6-4-5-25(36)22(27)16-29(41)33(19)39-26)28(40(2)47(3,43)44)17-30(24)46-34(32)20-8-12-31(38-18-20)45-21-9-10-21;1-37-35(42)32-24-15-23(27-12-9-20-13-14-41-28-6-4-5-25(36)22(28)16-30(41)33(20)39-27)29(40(2)46(3,43)44)17-31(24)45-34(32)21-10-11-26(38-18-21)19-7-8-19;1-34(36,37)29-11-9-19(17-39-29)32-30(33(43)38-2)22-14-21(26(16-28(22)46-32)41(3)47(4,44)45)24-10-8-18-12-13-42-25-7-5-6-23(35)20(25)15-27(42)31(18)40-24;1-18(35)45-30-11-9-20(17-38-30)33-31(34(42)37-2)23-14-22(27(16-29(23)46-33)40(3)47(4,43)44)25-10-8-19-12-13-41-26-7-5-6-24(36)21(26)15-28(41)32(19)39-25;1-18(35)25-10-9-20(17-38-25)33-31(34(42)37-2)23-14-22(28(16-30(23)45-33)40(3)46(4,43)44)26-11-8-19-12-13-41-27-7-5-6-24(36)21(27)15-29(41)32(19)39-26;1-18-8-9-20(17-36-18)32-30(33(40)35-2)23-14-22(27(16-29(23)43-32)38(3)44(4,41)42)25-11-10-19-12-13-39-26-7-5-6-24(34)21(26)15-28(39)31(19)37-25/h5-11,14-17H,12-13,18H2,1-4H3,(H,39,44);4-8,11-12,15-18,21H,9-10,13-14H2,1-3H3,(H,37,42);4-6,9-12,15-19H,7-8,13-14H2,1-3H3,(H,37,42);5-11,14-17H,12-13H2,1-4H3,(H,38,43);5-11,14-18H,12-13H2,1-4H3,(H,37,42);5-11,14-18H,12-13H2,1-4H3,(H,37,42);5-11,14-17H,12-13H2,1-4H3,(H,35,40)
InChIKeyALGXZPYWKPUWLC-UHFFFAOYSA-N
MW4545.93 g/mol
LogP45.00
Rot. Bonds45

About 2-(6-cyclopropyloxy-3-pyridinyl)-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;2-(6-cyclopropyl-3-pyridinyl)-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;2-[6-(1,1-difluoroethyl)-3-pyridinyl]-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;2-[6-(2,2-difluoropropoxy)-3-pyridinyl]-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-2-[6-(1-fluoroethoxy)-3-pyridinyl]-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-2-[6-(1-fluoroethyl)-3-pyridinyl]-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(6-methyl-3-pyridinyl)-1-benzofuran-3-carboxamide

2-(6-cyclopropyloxy-3-pyridinyl)-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;2-(6-cyclopropyl-3-pyridinyl)-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;2-[6-(1,1-difluoroethyl)-3-pyridinyl]-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;2-[6-(2,2-difluoropropoxy)-3-pyridinyl]-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-2-[6-(1-fluoroethoxy)-3-pyridinyl]-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-2-[6-(1-fluoroethyl)-3-pyridinyl]-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(6-methyl-3-pyridinyl)-1-benzofuran-3-carboxamide (PubChem CID 157151283) has the molecular formula C240H204F13N35O31S7 and a molecular weight of 4545.93 g/mol. Its IUPAC name is 2-(6-cyclopropyloxy-3-pyridinyl)-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;2-(6-cyclopropyl-3-pyridinyl)-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;2-[6-(1,1-difluoroethyl)-3-pyridinyl]-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;2-[6-(2,2-difluoropropoxy)-3-pyridinyl]-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-2-[6-(1-fluoroethoxy)-3-pyridinyl]-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-2-[6-(1-fluoroethyl)-3-pyridinyl]-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(6-methyl-3-pyridinyl)-1-benzofuran-3-carboxamide.

Molecular Properties

Compound Name2-(6-cyclopropyloxy-3-pyridinyl)-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;2-(6-cyclopropyl-3-pyridinyl)-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;2-[6-(1,1-difluoroethyl)-3-pyridinyl]-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;2-[6-(2,2-difluoropropoxy)-3-pyridinyl]-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-2-[6-(1-fluoroethoxy)-3-pyridinyl]-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-2-[6-(1-fluoroethyl)-3-pyridinyl]-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(6-methyl-3-pyridinyl)-1-benzofuran-3-carboxamide
PubChem CID157151283
Molecular FormulaC240H204F13N35O31S7
Molecular Weight4545.93 g/mol
Exact Mass4542.33
IUPAC Name2-(6-cyclopropyloxy-3-pyridinyl)-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;2-(6-cyclopropyl-3-pyridinyl)-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;2-[6-(1,1-difluoroethyl)-3-pyridinyl]-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;2-[6-(2,2-difluoropropoxy)-3-pyridinyl]-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-2-[6-(1-fluoroethoxy)-3-pyridinyl]-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-2-[6-(1-fluoroethyl)-3-pyridinyl]-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(6-methyl-3-pyridinyl)-1-benzofuran-3-carboxamide
SMILESCNC(=O)c1c(-c2ccc(C(C)(F)F)nc2)oc2cc(N(C)S(C)(=O)=O)c(-c3ccc4c(n3)-c3cc5c(F)cccc5n3CC4)cc12.CNC(=O)c1c(-c2ccc(C(C)F)nc2)oc2cc(N(C)S(C)(=O)=O)c(-c3ccc4c(n3)-c3cc5c(F)cccc5n3CC4)cc12.CNC(=O)c1c(-c2ccc(C)nc2)oc2cc(N(C)S(C)(=O)=O)c(-c3ccc4c(n3)-c3cc5c(F)cccc5n3CC4)cc12.CNC(=O)c1c(-c2ccc(C3CC3)nc2)oc2cc(N(C)S(C)(=O)=O)c(-c3ccc4c(n3)-c3cc5c(F)cccc5n3CC4)cc12.CNC(=O)c1c(-c2ccc(OC(C)F)nc2)oc2cc(N(C)S(C)(=O)=O)c(-c3ccc4c(n3)-c3cc5c(F)cccc5n3CC4)cc12.CNC(=O)c1c(-c2ccc(OC3CC3)nc2)oc2cc(N(C)S(C)(=O)=O)c(-c3ccc4c(n3)-c3cc5c(F)cccc5n3CC4)cc12.CNC(=O)c1c(-c2ccc(OCC(C)(F)F)nc2)oc2cc(N(C)S(C)(=O)=O)c(-c3ccc4c(n3)-c3cc5c(F)cccc5n3CC4)cc12
InChIInChI=1S/C35H30F3N5O5S.C35H30FN5O5S.C35H30FN5O4S.C34H28F3N5O4S.C34H29F2N5O5S.C34H29F2N5O4S.C33H28FN5O4S/c1-35(37,38)18-47-30-11-9-20(17-40-30)33-31(34(44)39-2)23-14-22(27(16-29(23)48-33)42(3)49(4,45)46)25-10-8-19-12-13-43-26-7-5-6-24(36)21(26)15-28(43)32(19)41-25;1-37-35(42)32-24-15-23(26-11-7-19-13-14-41-27-6-4-5-25(36)22(27)16-29(41)33(19)39-26)28(40(2)47(3,43)44)17-30(24)46-34(32)20-8-12-31(38-18-20)45-21-9-10-21;1-37-35(42)32-24-15-23(27-12-9-20-13-14-41-28-6-4-5-25(36)22(28)16-30(41)33(20)39-27)29(40(2)46(3,43)44)17-31(24)45-34(32)21-10-11-26(38-18-21)19-7-8-19;1-34(36,37)29-11-9-19(17-39-29)32-30(33(43)38-2)22-14-21(26(16-28(22)46-32)41(3)47(4,44)45)24-10-8-18-12-13-42-25-7-5-6-23(35)20(25)15-27(42)31(18)40-24;1-18(35)45-30-11-9-20(17-38-30)33-31(34(42)37-2)23-14-22(27(16-29(23)46-33)40(3)47(4,43)44)25-10-8-19-12-13-41-26-7-5-6-24(36)21(26)15-28(41)32(19)39-25;1-18(35)25-10-9-20(17-38-25)33-31(34(42)37-2)23-14-22(28(16-30(23)45-33)40(3)46(4,43)44)26-11-8-19-12-13-41-27-7-5-6-24(36)21(27)15-29(41)32(19)39-26;1-18-8-9-20(17-36-18)32-30(33(40)35-2)23-14-22(27(16-29(23)43-32)38(3)44(4,41)42)25-11-10-19-12-13-39-26-7-5-6-24(34)21(26)15-28(39)31(19)37-25/h5-11,14-17H,12-13,18H2,1-4H3,(H,39,44);4-8,11-12,15-18,21H,9-10,13-14H2,1-3H3,(H,37,42);4-6,9-12,15-19H,7-8,13-14H2,1-3H3,(H,37,42);5-11,14-17H,12-13H2,1-4H3,(H,38,43);5-11,14-18H,12-13H2,1-4H3,(H,37,42);5-11,14-18H,12-13H2,1-4H3,(H,37,42);5-11,14-17H,12-13H2,1-4H3,(H,35,40)
InChIKeyALGXZPYWKPUWLC-UHFFFAOYSA-N
XLogP45.00
TPSA800.00 Ų
H-Bond Donors7
H-Bond Acceptors52
Rotatable Bonds45
Heavy Atoms326
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5004545.93
LogP ≤ 545.00
H-Bond Donors ≤ 57
H-Bond Acceptors ≤ 1052

Analyze 2-(6-cyclopropyloxy-3-pyridinyl)-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;2-(6-cyclopropyl-3-pyridinyl)-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;2-[6-(1,1-difluoroethyl)-3-pyridinyl]-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;2-[6-(2,2-difluoropropoxy)-3-pyridinyl]-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-2-[6-(1-fluoroethoxy)-3-pyridinyl]-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-2-[6-(1-fluoroethyl)-3-pyridinyl]-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(6-methyl-3-pyridinyl)-1-benzofuran-3-carboxamide with MolForge

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Frequently Asked Questions

What is the IUPAC name of 2-(6-cyclopropyloxy-3-pyridinyl)-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;2-(6-cyclopropyl-3-pyridinyl)-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;2-[6-(1,1-difluoroethyl)-3-pyridinyl]-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;2-[6-(2,2-difluoropropoxy)-3-pyridinyl]-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-2-[6-(1-fluoroethoxy)-3-pyridinyl]-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-2-[6-(1-fluoroethyl)-3-pyridinyl]-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(6-methyl-3-pyridinyl)-1-benzofuran-3-carboxamide?
The IUPAC name of 2-(6-cyclopropyloxy-3-pyridinyl)-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;2-(6-cyclopropyl-3-pyridinyl)-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;2-[6-(1,1-difluoroethyl)-3-pyridinyl]-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;2-[6-(2,2-difluoropropoxy)-3-pyridinyl]-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-2-[6-(1-fluoroethoxy)-3-pyridinyl]-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-2-[6-(1-fluoroethyl)-3-pyridinyl]-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(6-methyl-3-pyridinyl)-1-benzofuran-3-carboxamide (CID 157151283) is 2-(6-cyclopropyloxy-3-pyridinyl)-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;2-(6-cyclopropyl-3-pyridinyl)-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;2-[6-(1,1-difluoroethyl)-3-pyridinyl]-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;2-[6-(2,2-difluoropropoxy)-3-pyridinyl]-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-2-[6-(1-fluoroethoxy)-3-pyridinyl]-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-2-[6-(1-fluoroethyl)-3-pyridinyl]-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(6-methyl-3-pyridinyl)-1-benzofuran-3-carboxamide.
What is the SMILES notation for 2-(6-cyclopropyloxy-3-pyridinyl)-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;2-(6-cyclopropyl-3-pyridinyl)-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;2-[6-(1,1-difluoroethyl)-3-pyridinyl]-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;2-[6-(2,2-difluoropropoxy)-3-pyridinyl]-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-2-[6-(1-fluoroethoxy)-3-pyridinyl]-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-2-[6-(1-fluoroethyl)-3-pyridinyl]-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(6-methyl-3-pyridinyl)-1-benzofuran-3-carboxamide?
The canonical SMILES for 2-(6-cyclopropyloxy-3-pyridinyl)-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;2-(6-cyclopropyl-3-pyridinyl)-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;2-[6-(1,1-difluoroethyl)-3-pyridinyl]-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;2-[6-(2,2-difluoropropoxy)-3-pyridinyl]-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-2-[6-(1-fluoroethoxy)-3-pyridinyl]-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-2-[6-(1-fluoroethyl)-3-pyridinyl]-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(6-methyl-3-pyridinyl)-1-benzofuran-3-carboxamide is CNC(=O)c1c(-c2ccc(C(C)(F)F)nc2)oc2cc(N(C)S(C)(=O)=O)c(-c3ccc4c(n3)-c3cc5c(F)cccc5n3CC4)cc12.CNC(=O)c1c(-c2ccc(C(C)F)nc2)oc2cc(N(C)S(C)(=O)=O)c(-c3ccc4c(n3)-c3cc5c(F)cccc5n3CC4)cc12.CNC(=O)c1c(-c2ccc(C)nc2)oc2cc(N(C)S(C)(=O)=O)c(-c3ccc4c(n3)-c3cc5c(F)cccc5n3CC4)cc12.CNC(=O)c1c(-c2ccc(C3CC3)nc2)oc2cc(N(C)S(C)(=O)=O)c(-c3ccc4c(n3)-c3cc5c(F)cccc5n3CC4)cc12.CNC(=O)c1c(-c2ccc(OC(C)F)nc2)oc2cc(N(C)S(C)(=O)=O)c(-c3ccc4c(n3)-c3cc5c(F)cccc5n3CC4)cc12.CNC(=O)c1c(-c2ccc(OC3CC3)nc2)oc2cc(N(C)S(C)(=O)=O)c(-c3ccc4c(n3)-c3cc5c(F)cccc5n3CC4)cc12.CNC(=O)c1c(-c2ccc(OCC(C)(F)F)nc2)oc2cc(N(C)S(C)(=O)=O)c(-c3ccc4c(n3)-c3cc5c(F)cccc5n3CC4)cc12.
What is the InChIKey of 2-(6-cyclopropyloxy-3-pyridinyl)-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;2-(6-cyclopropyl-3-pyridinyl)-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;2-[6-(1,1-difluoroethyl)-3-pyridinyl]-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;2-[6-(2,2-difluoropropoxy)-3-pyridinyl]-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-2-[6-(1-fluoroethoxy)-3-pyridinyl]-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-2-[6-(1-fluoroethyl)-3-pyridinyl]-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(6-methyl-3-pyridinyl)-1-benzofuran-3-carboxamide?
The InChIKey is ALGXZPYWKPUWLC-UHFFFAOYSA-N. The full InChI is InChI=1S/C35H30F3N5O5S.C35H30FN5O5S.C35H30FN5O4S.C34H28F3N5O4S.C34H29F2N5O5S.C34H29F2N5O4S.C33H28FN5O4S/c1-35(37,38)18-47-30-11-9-20(17-40-30)33-31(34(44)39-2)23-14-22(27(16-29(23)48-33)42(3)49(4,45)46)25-10-8-19-12-13-43-26-7-5-6-24(36)21(26)15-28(43)32(19)41-25;1-37-35(42)32-24-15-23(26-11-7-19-13-14-41-27-6-4-5-25(36)22(27)16-29(41)33(19)39-26)28(40(2)47(3,43)44)17-30(24)46-34(32)20-8-12-31(38-18-20)45-21-9-10-21;1-37-35(42)32-24-15-23(27-12-9-20-13-14-41-28-6-4-5-25(36)22(28)16-30(41)33(20)39-27)29(40(2)46(3,43)44)17-31(24)45-34(32)21-10-11-26(38-18-21)19-7-8-19;1-34(36,37)29-11-9-19(17-39-29)32-30(33(43)38-2)22-14-21(26(16-28(22)46-32)41(3)47(4,44)45)24-10-8-18-12-13-42-25-7-5-6-23(35)20(25)15-27(42)31(18)40-24;1-18(35)45-30-11-9-20(17-38-30)33-31(34(42)37-2)23-14-22(27(16-29(23)46-33)40(3)47(4,43)44)25-10-8-19-12-13-41-26-7-5-6-24(36)21(26)15-28(41)32(19)39-25;1-18(35)25-10-9-20(17-38-25)33-31(34(42)37-2)23-14-22(28(16-30(23)45-33)40(3)46(4,43)44)26-11-8-19-12-13-41-27-7-5-6-24(36)21(27)15-29(41)32(19)39-26;1-18-8-9-20(17-36-18)32-30(33(40)35-2)23-14-22(27(16-29(23)43-32)38(3)44(4,41)42)25-11-10-19-12-13-39-26-7-5-6-24(34)21(26)15-28(39)31(19)37-25/h5-11,14-17H,12-13,18H2,1-4H3,(H,39,44);4-8,11-12,15-18,21H,9-10,13-14H2,1-3H3,(H,37,42);4-6,9-12,15-19H,7-8,13-14H2,1-3H3,(H,37,42);5-11,14-17H,12-13H2,1-4H3,(H,38,43);5-11,14-18H,12-13H2,1-4H3,(H,37,42);5-11,14-18H,12-13H2,1-4H3,(H,37,42);5-11,14-17H,12-13H2,1-4H3,(H,35,40).
What are the key properties of 2-(6-cyclopropyloxy-3-pyridinyl)-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;2-(6-cyclopropyl-3-pyridinyl)-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;2-[6-(1,1-difluoroethyl)-3-pyridinyl]-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;2-[6-(2,2-difluoropropoxy)-3-pyridinyl]-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-2-[6-(1-fluoroethoxy)-3-pyridinyl]-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-2-[6-(1-fluoroethyl)-3-pyridinyl]-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(6-methyl-3-pyridinyl)-1-benzofuran-3-carboxamide?
2-(6-cyclopropyloxy-3-pyridinyl)-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;2-(6-cyclopropyl-3-pyridinyl)-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;2-[6-(1,1-difluoroethyl)-3-pyridinyl]-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;2-[6-(2,2-difluoropropoxy)-3-pyridinyl]-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-2-[6-(1-fluoroethoxy)-3-pyridinyl]-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-2-[6-(1-fluoroethyl)-3-pyridinyl]-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(6-methyl-3-pyridinyl)-1-benzofuran-3-carboxamide has a molecular weight of 4545.93 g/mol, XLogP of 45.00, 45 rotatable bonds, 7 hydrogen bond donors, and 52 hydrogen bond acceptors.
Where does this data come from?
All data for 2-(6-cyclopropyloxy-3-pyridinyl)-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;2-(6-cyclopropyl-3-pyridinyl)-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;2-[6-(1,1-difluoroethyl)-3-pyridinyl]-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;2-[6-(2,2-difluoropropoxy)-3-pyridinyl]-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-2-[6-(1-fluoroethoxy)-3-pyridinyl]-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-2-[6-(1-fluoroethyl)-3-pyridinyl]-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(6-methyl-3-pyridinyl)-1-benzofuran-3-carboxamide is sourced from PubChem (CID 157151283), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).