N-[(6-amino-2-pyridinyl)sulfonyl]-2-(3,3-dimethylpiperidin-1-yl)-6-(6-propan-2-yloxy-3-pyridinyl)pyridine-3-carboxamide;N-[(6-amino-2-pyridinyl)sulfonyl]-6-(5-methoxy-2-methylphenyl)-5-methyl-2-(2,2,4-trimethylpyrrolidin-1-yl)pyridine-3-carboxamide;2-(3-cyclopropylpiperidin-1-yl)-6-[3-fluoro-5-(2-methylpropoxy)phenyl]-N-(1H-pyrazol-5-ylsulfonyl)pyridine-3-carboxamide;2-[(2S,5R)-2,5-dimethylpyrrolidin-1-yl]-6-(3-fluoro-5-propan-2-yloxyphenyl)-N-(1H-pyrazol-5-ylsulfonyl)pyridine-3-carboxamide

C104H125F2N21O16S4 — CID 157155722

About N-[(6-amino-2-pyridinyl)sulfonyl]-2-(3,3-dimethylpiperidin-1-yl)-6-(6-propan-2-yloxy-3-pyridinyl)pyridine-3-carboxamide;N-[(6-amino-2-pyridinyl)sulfonyl]-6-(5-methoxy-2-methylphenyl)-5-methyl-2-(2,2,4-trimethylpyrrolidin-1-yl)pyridine-3-carboxamide;2-(3-cyclopropylpiperidin-1-yl)-6-[3-fluoro-5-(2-methylpropoxy)phenyl]-N-(1H-pyrazol-5-ylsulfonyl)pyridine-3-carboxamide;2-[(2S,5R)-2,5-dimethylpyrrolidin-1-yl]-6-(3-fluoro-5-propan-2-yloxyphenyl)-N-(1H-pyrazol-5-ylsulfonyl)pyridine-3-carboxamide

N-[(6-amino-2-pyridinyl)sulfonyl]-2-(3,3-dimethylpiperidin-1-yl)-6-(6-propan-2-yloxy-3-pyridinyl)pyridine-3-carboxamide;N-[(6-amino-2-pyridinyl)sulfonyl]-6-(5-methoxy-2-methylphenyl)-5-methyl-2-(2,2,4-trimethylpyrrolidin-1-yl)pyridine-3-carboxamide;2-(3-cyclopropylpiperidin-1-yl)-6-[3-fluoro-5-(2-methylpropoxy)phenyl]-N-(1H-pyrazol-5-ylsulfonyl)pyridine-3-carboxamide;2-[(2S,5R)-2,5-dimethylpyrrolidin-1-yl]-6-(3-fluoro-5-propan-2-yloxyphenyl)-N-(1H-pyrazol-5-ylsulfonyl)pyridine-3-carboxamide (PubChem CID 157155722) has the molecular formula C104H125F2N21O16S4 and a molecular weight of 2091.54 g/mol. Its IUPAC name is N-[(6-amino-2-pyridinyl)sulfonyl]-2-(3,3-dimethylpiperidin-1-yl)-6-(6-propan-2-yloxy-3-pyridinyl)pyridine-3-carboxamide;N-[(6-amino-2-pyridinyl)sulfonyl]-6-(5-methoxy-2-methylphenyl)-5-methyl-2-(2,2,4-trimethylpyrrolidin-1-yl)pyridine-3-carboxamide;2-(3-cyclopropylpiperidin-1-yl)-6-[3-fluoro-5-(2-methylpropoxy)phenyl]-N-(1H-pyrazol-5-ylsulfonyl)pyridine-3-carboxamide;2-[(2S,5R)-2,5-dimethylpyrrolidin-1-yl]-6-(3-fluoro-5-propan-2-yloxyphenyl)-N-(1H-pyrazol-5-ylsulfonyl)pyridine-3-carboxamide.

Molecular Properties

• Compound Name: N-[(6-amino-2-pyridinyl)sulfonyl]-2-(3,3-dimethylpiperidin-1-yl)-6-(6-propan-2-yloxy-3-pyridinyl)pyridine-3-carboxamide;N-[(6-amino-2-pyridinyl)sulfonyl]-6-(5-methoxy-2-methylphenyl)-5-methyl-2-(2,2,4-trimethylpyrrolidin-1-yl)pyridine-3-carboxamide;2-(3-cyclopropylpiperidin-1-yl)-6-[3-fluoro-5-(2-methylpropoxy)phenyl]-N-(1H-pyrazol-5-ylsulfonyl)pyridine-3-carboxamide;2-[(2S,5R)-2,5-dimethylpyrrolidin-1-yl]-6-(3-fluoro-5-propan-2-yloxyphenyl)-N-(1H-pyrazol-5-ylsulfonyl)pyridine-3-carboxamide
• PubChem CID: 157155722
• Molecular Formula: C104H125F2N21O16S4
• Molecular Weight: 2091.54 g/mol
• Exact Mass: 2089.85
• IUPAC Name: N-[(6-amino-2-pyridinyl)sulfonyl]-2-(3,3-dimethylpiperidin-1-yl)-6-(6-propan-2-yloxy-3-pyridinyl)pyridine-3-carboxamide;N-[(6-amino-2-pyridinyl)sulfonyl]-6-(5-methoxy-2-methylphenyl)-5-methyl-2-(2,2,4-trimethylpyrrolidin-1-yl)pyridine-3-carboxamide;2-(3-cyclopropylpiperidin-1-yl)-6-[3-fluoro-5-(2-methylpropoxy)phenyl]-N-(1H-pyrazol-5-ylsulfonyl)pyridine-3-carboxamide;2-[(2S,5R)-2,5-dimethylpyrrolidin-1-yl]-6-(3-fluoro-5-propan-2-yloxyphenyl)-N-(1H-pyrazol-5-ylsulfonyl)pyridine-3-carboxamide
• SMILES: CC(C)COc1cc(F)cc(-c2ccc(C(=O)NS(=O)(=O)c3ccn[nH]3)c(N3CCCC(C4CC4)C3)n2)c1.CC(C)Oc1cc(F)cc(-c2ccc(C(=O)NS(=O)(=O)c3ccn[nH]3)c(N3[C@H](C)CC[C@@H]3C)n2)c1.CC(C)Oc1ccc(-c2ccc(C(=O)NS(=O)(=O)c3cccc(N)n3)c(N3CCCC(C)(C)C3)n2)cn1.COc1ccc(C)c(-c2nc(N3CC(C)CC3(C)C)c(C(=O)NS(=O)(=O)c3cccc(N)n3)cc2C)c1
• InChI: InChI=1S/C27H32FN5O4S.C27H33N5O4S.C26H32N6O4S.C24H28FN5O4S/c1-17(2)16-37-22-13-20(12-21(28)14-22)24-8-7-23(27(34)32-38(35,36)25-9-10-29-31-25)26(30-24)33-11-3-4-19(15-33)18-5-6-18;1-16-14-27(4,5)32(15-16)25-21(26(33)31-37(34,35)23-9-7-8-22(28)29-23)12-18(3)24(30-25)20-13-19(36-6)11-10-17(20)2;1-17(2)36-22-12-9-18(15-28-22)20-11-10-19(24(29-20)32-14-6-13-26(3,4)16-32)25(33)31-37(34,35)23-8-5-7-21(27)30-23;1-14(2)34-19-12-17(11-18(25)13-19)21-8-7-20(23(27-21)30-15(3)5-6-16(30)4)24(31)29-35(32,33)22-9-10-26-28-22/h7-10,12-14,17-19H,3-6,11,15-16H2,1-2H3,(H,29,31)(H,32,34);7-13,16H,14-15H2,1-6H3,(H2,28,29)(H,31,33);5,7-12,15,17H,6,13-14,16H2,1-4H3,(H2,27,30)(H,31,33);7-16H,5-6H2,1-4H3,(H,26,28)(H,29,31)/t;;;15-,16+
• InChIKey: ALTYFVIRVCODBN-UTUFBNIDSA-N
• XLogP: 16.03
• TPSA: 502.47 Ų
• H-Bond Donors: 8
• H-Bond Acceptors: 31
• Rotatable Bonds: 29
• Heavy Atoms: 147
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2091.54
LogP ≤ 5	16.03
H-Bond Donors ≤ 5	8
H-Bond Acceptors ≤ 10	31

Frequently Asked Questions

What is the IUPAC name of N-[(6-amino-2-pyridinyl)sulfonyl]-2-(3,3-dimethylpiperidin-1-yl)-6-(6-propan-2-yloxy-3-pyridinyl)pyridine-3-carboxamide;N-[(6-amino-2-pyridinyl)sulfonyl]-6-(5-methoxy-2-methylphenyl)-5-methyl-2-(2,2,4-trimethylpyrrolidin-1-yl)pyridine-3-carboxamide;2-(3-cyclopropylpiperidin-1-yl)-6-[3-fluoro-5-(2-methylpropoxy)phenyl]-N-(1H-pyrazol-5-ylsulfonyl)pyridine-3-carboxamide;2-[(2S,5R)-2,5-dimethylpyrrolidin-1-yl]-6-(3-fluoro-5-propan-2-yloxyphenyl)-N-(1H-pyrazol-5-ylsulfonyl)pyridine-3-carboxamide?

The IUPAC name of N-[(6-amino-2-pyridinyl)sulfonyl]-2-(3,3-dimethylpiperidin-1-yl)-6-(6-propan-2-yloxy-3-pyridinyl)pyridine-3-carboxamide;N-[(6-amino-2-pyridinyl)sulfonyl]-6-(5-methoxy-2-methylphenyl)-5-methyl-2-(2,2,4-trimethylpyrrolidin-1-yl)pyridine-3-carboxamide;2-(3-cyclopropylpiperidin-1-yl)-6-[3-fluoro-5-(2-methylpropoxy)phenyl]-N-(1H-pyrazol-5-ylsulfonyl)pyridine-3-carboxamide;2-[(2S,5R)-2,5-dimethylpyrrolidin-1-yl]-6-(3-fluoro-5-propan-2-yloxyphenyl)-N-(1H-pyrazol-5-ylsulfonyl)pyridine-3-carboxamide (CID 157155722) is N-[(6-amino-2-pyridinyl)sulfonyl]-2-(3,3-dimethylpiperidin-1-yl)-6-(6-propan-2-yloxy-3-pyridinyl)pyridine-3-carboxamide;N-[(6-amino-2-pyridinyl)sulfonyl]-6-(5-methoxy-2-methylphenyl)-5-methyl-2-(2,2,4-trimethylpyrrolidin-1-yl)pyridine-3-carboxamide;2-(3-cyclopropylpiperidin-1-yl)-6-[3-fluoro-5-(2-methylpropoxy)phenyl]-N-(1H-pyrazol-5-ylsulfonyl)pyridine-3-carboxamide;2-[(2S,5R)-2,5-dimethylpyrrolidin-1-yl]-6-(3-fluoro-5-propan-2-yloxyphenyl)-N-(1H-pyrazol-5-ylsulfonyl)pyridine-3-carboxamide.

What is the SMILES notation for N-[(6-amino-2-pyridinyl)sulfonyl]-2-(3,3-dimethylpiperidin-1-yl)-6-(6-propan-2-yloxy-3-pyridinyl)pyridine-3-carboxamide;N-[(6-amino-2-pyridinyl)sulfonyl]-6-(5-methoxy-2-methylphenyl)-5-methyl-2-(2,2,4-trimethylpyrrolidin-1-yl)pyridine-3-carboxamide;2-(3-cyclopropylpiperidin-1-yl)-6-[3-fluoro-5-(2-methylpropoxy)phenyl]-N-(1H-pyrazol-5-ylsulfonyl)pyridine-3-carboxamide;2-[(2S,5R)-2,5-dimethylpyrrolidin-1-yl]-6-(3-fluoro-5-propan-2-yloxyphenyl)-N-(1H-pyrazol-5-ylsulfonyl)pyridine-3-carboxamide?

The canonical SMILES for N-[(6-amino-2-pyridinyl)sulfonyl]-2-(3,3-dimethylpiperidin-1-yl)-6-(6-propan-2-yloxy-3-pyridinyl)pyridine-3-carboxamide;N-[(6-amino-2-pyridinyl)sulfonyl]-6-(5-methoxy-2-methylphenyl)-5-methyl-2-(2,2,4-trimethylpyrrolidin-1-yl)pyridine-3-carboxamide;2-(3-cyclopropylpiperidin-1-yl)-6-[3-fluoro-5-(2-methylpropoxy)phenyl]-N-(1H-pyrazol-5-ylsulfonyl)pyridine-3-carboxamide;2-[(2S,5R)-2,5-dimethylpyrrolidin-1-yl]-6-(3-fluoro-5-propan-2-yloxyphenyl)-N-(1H-pyrazol-5-ylsulfonyl)pyridine-3-carboxamide is CC(C)COc1cc(F)cc(-c2ccc(C(=O)NS(=O)(=O)c3ccn[nH]3)c(N3CCCC(C4CC4)C3)n2)c1.CC(C)Oc1cc(F)cc(-c2ccc(C(=O)NS(=O)(=O)c3ccn[nH]3)c(N3[C@H](C)CC[C@@H]3C)n2)c1.CC(C)Oc1ccc(-c2ccc(C(=O)NS(=O)(=O)c3cccc(N)n3)c(N3CCCC(C)(C)C3)n2)cn1.COc1ccc(C)c(-c2nc(N3CC(C)CC3(C)C)c(C(=O)NS(=O)(=O)c3cccc(N)n3)cc2C)c1.

What is the InChIKey of N-[(6-amino-2-pyridinyl)sulfonyl]-2-(3,3-dimethylpiperidin-1-yl)-6-(6-propan-2-yloxy-3-pyridinyl)pyridine-3-carboxamide;N-[(6-amino-2-pyridinyl)sulfonyl]-6-(5-methoxy-2-methylphenyl)-5-methyl-2-(2,2,4-trimethylpyrrolidin-1-yl)pyridine-3-carboxamide;2-(3-cyclopropylpiperidin-1-yl)-6-[3-fluoro-5-(2-methylpropoxy)phenyl]-N-(1H-pyrazol-5-ylsulfonyl)pyridine-3-carboxamide;2-[(2S,5R)-2,5-dimethylpyrrolidin-1-yl]-6-(3-fluoro-5-propan-2-yloxyphenyl)-N-(1H-pyrazol-5-ylsulfonyl)pyridine-3-carboxamide?

The InChIKey is ALTYFVIRVCODBN-UTUFBNIDSA-N. The full InChI is InChI=1S/C27H32FN5O4S.C27H33N5O4S.C26H32N6O4S.C24H28FN5O4S/c1-17(2)16-37-22-13-20(12-21(28)14-22)24-8-7-23(27(34)32-38(35,36)25-9-10-29-31-25)26(30-24)33-11-3-4-19(15-33)18-5-6-18;1-16-14-27(4,5)32(15-16)25-21(26(33)31-37(34,35)23-9-7-8-22(28)29-23)12-18(3)24(30-25)20-13-19(36-6)11-10-17(20)2;1-17(2)36-22-12-9-18(15-28-22)20-11-10-19(24(29-20)32-14-6-13-26(3,4)16-32)25(33)31-37(34,35)23-8-5-7-21(27)30-23;1-14(2)34-19-12-17(11-18(25)13-19)21-8-7-20(23(27-21)30-15(3)5-6-16(30)4)24(31)29-35(32,33)22-9-10-26-28-22/h7-10,12-14,17-19H,3-6,11,15-16H2,1-2H3,(H,29,31)(H,32,34);7-13,16H,14-15H2,1-6H3,(H2,28,29)(H,31,33);5,7-12,15,17H,6,13-14,16H2,1-4H3,(H2,27,30)(H,31,33);7-16H,5-6H2,1-4H3,(H,26,28)(H,29,31)/t;;;15-,16+.

What are the key properties of N-[(6-amino-2-pyridinyl)sulfonyl]-2-(3,3-dimethylpiperidin-1-yl)-6-(6-propan-2-yloxy-3-pyridinyl)pyridine-3-carboxamide;N-[(6-amino-2-pyridinyl)sulfonyl]-6-(5-methoxy-2-methylphenyl)-5-methyl-2-(2,2,4-trimethylpyrrolidin-1-yl)pyridine-3-carboxamide;2-(3-cyclopropylpiperidin-1-yl)-6-[3-fluoro-5-(2-methylpropoxy)phenyl]-N-(1H-pyrazol-5-ylsulfonyl)pyridine-3-carboxamide;2-[(2S,5R)-2,5-dimethylpyrrolidin-1-yl]-6-(3-fluoro-5-propan-2-yloxyphenyl)-N-(1H-pyrazol-5-ylsulfonyl)pyridine-3-carboxamide?

N-[(6-amino-2-pyridinyl)sulfonyl]-2-(3,3-dimethylpiperidin-1-yl)-6-(6-propan-2-yloxy-3-pyridinyl)pyridine-3-carboxamide;N-[(6-amino-2-pyridinyl)sulfonyl]-6-(5-methoxy-2-methylphenyl)-5-methyl-2-(2,2,4-trimethylpyrrolidin-1-yl)pyridine-3-carboxamide;2-(3-cyclopropylpiperidin-1-yl)-6-[3-fluoro-5-(2-methylpropoxy)phenyl]-N-(1H-pyrazol-5-ylsulfonyl)pyridine-3-carboxamide;2-[(2S,5R)-2,5-dimethylpyrrolidin-1-yl]-6-(3-fluoro-5-propan-2-yloxyphenyl)-N-(1H-pyrazol-5-ylsulfonyl)pyridine-3-carboxamide has a molecular weight of 2091.54 g/mol, XLogP of 16.03, 29 rotatable bonds, 8 hydrogen bond donors, and 31 hydrogen bond acceptors.

Where does this data come from?

All data for N-[(6-amino-2-pyridinyl)sulfonyl]-2-(3,3-dimethylpiperidin-1-yl)-6-(6-propan-2-yloxy-3-pyridinyl)pyridine-3-carboxamide;N-[(6-amino-2-pyridinyl)sulfonyl]-6-(5-methoxy-2-methylphenyl)-5-methyl-2-(2,2,4-trimethylpyrrolidin-1-yl)pyridine-3-carboxamide;2-(3-cyclopropylpiperidin-1-yl)-6-[3-fluoro-5-(2-methylpropoxy)phenyl]-N-(1H-pyrazol-5-ylsulfonyl)pyridine-3-carboxamide;2-[(2S,5R)-2,5-dimethylpyrrolidin-1-yl]-6-(3-fluoro-5-propan-2-yloxyphenyl)-N-(1H-pyrazol-5-ylsulfonyl)pyridine-3-carboxamide is sourced from PubChem (CID 157155722), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).