1-(cyclobutylmethyl)-8-(dimethylamino)-3-(5-hydroxy-2-oxopentyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[4-(2-methoxypyrimidin-5-yl)-2-oxobutyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(4-methoxypyrimidin-2-yl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(5-methylsulfanyl-2-pyridinyl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(6-methylsulfanyl-2-pyridinyl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-(2-oxobutyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[2-oxo-3-(6-oxo-1H-pyridin-2-yl)propyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;4-[3-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-2-oxopropyl]pyrimidine-5-carbonitrile;8-(dimethylamino)-3-(5-hydroxy-2-oxopentyl)-1-(2-methoxyethyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-1-(2-methoxyethyl)-3-(2-oxobutyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;5-[8-(dimethylamino)-1-(2-methoxyethyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-oxopentanamide;8-(dimethylamino)-1-(2-methoxyethyl)-3-(2-oxo-3-pyrimidin-4-ylpropyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one

C325H453N49O34S2 — CID 157157125

IUPAC1-(cyclobutylmethyl)-8-(dimethylamino)-3-(5-hydroxy-2-oxopentyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[4-(2-methoxypyrimidin-5-yl)-2-oxobutyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(4-methoxypyrimidin-2-yl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(5-methylsulfanyl-2-pyridinyl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(6-methylsulfanyl-2-pyridinyl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-(2-oxobutyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[2-oxo-3-(6-oxo-1H-pyridin-2-yl)propyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;4-[3-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-2-oxopropyl]pyrimidine-5-carbonitrile;8-(dimethylamino)-3-(5-hydroxy-2-oxopentyl)-1-(2-methoxyethyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-1-(2-methoxyethyl)-3-(2-oxobutyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;5-[8-(dimethylamino)-1-(2-methoxyethyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-oxopentanamide;8-(dimethylamino)-1-(2-methoxyethyl)-3-(2-oxo-3-pyrimidin-4-ylpropyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one
SMILESCCC(=O)CN1CC2(CCC(c3ccccc3)(N(C)C)CC2)N(CC2CCC2)C1=O.CCC(=O)CN1CC2(CCC(c3ccccc3)(N(C)C)CC2)N(CCOC)C1=O.CN(C)C1(c2ccccc2)CCC2(CC1)CN(CC(=O)CCCO)C(=O)N2CC1CCC1.CN(C)C1(c2ccccc2)CCC2(CC1)CN(CC(=O)Cc1cccc(=O)[nH]1)C(=O)N2CC1CCC1.CN(C)C1(c2ccccc2)CCC2(CC1)CN(CC(=O)Cc1ncncc1C#N)C(=O)N2CC1CCC1.COCCN1C(=O)N(CC(=O)CCC(N)=O)CC12CCC(c1ccccc1)(N(C)C)CC2.COCCN1C(=O)N(CC(=O)CCCO)CC12CCC(c1ccccc1)(N(C)C)CC2.COCCN1C(=O)N(CC(=O)Cc2ccncn2)CC12CCC(c1ccccc1)(N(C)C)CC2.COc1ccnc(CC(=O)CN2CC3(CCC(c4ccccc4)(N(C)C)CC3)N(CC3CCC3)C2=O)n1.COc1ncc(CCC(=O)CN2CC3(CCC(c4ccccc4)(N(C)C)CC3)N(CC3CCC3)C2=O)cn1.CSc1ccc(CC(=O)CN2CC3(CCC(c4ccccc4)(N(C)C)CC3)N(CC3CCC3)C2=O)nc1.CSc1cccc(CC(=O)CN2CC3(CCC(c4ccccc4)(N(C)C)CC3)N(CC3CCC3)C2=O)n1
InChIInChI=1S/C30H41N5O3.2C30H40N4O2S.C29H36N6O2.C29H39N5O3.C29H38N4O3.C26H35N5O3.C26H39N3O3.C25H37N3O2.C24H36N4O4.C24H37N3O4.C23H35N3O3/c1-33(2)30(25-10-5-4-6-11-25)16-14-29(15-17-30)22-34(28(37)35(29)20-23-8-7-9-23)21-26(36)13-12-24-18-31-27(38-3)32-19-24;1-32(2)30(24-11-5-4-6-12-24)17-15-29(16-18-30)22-33(28(36)34(29)20-23-9-7-10-23)21-26(35)19-25-13-8-14-27(31-25)37-3;1-32(2)30(24-10-5-4-6-11-24)16-14-29(15-17-30)22-33(28(36)34(29)20-23-8-7-9-23)21-26(35)18-25-12-13-27(37-3)19-31-25;1-33(2)29(24-9-4-3-5-10-24)13-11-28(12-14-29)20-34(27(37)35(28)18-22-7-6-8-22)19-25(36)15-26-23(16-30)17-31-21-32-26;1-32(2)29(23-10-5-4-6-11-23)15-13-28(14-16-29)21-33(27(36)34(28)19-22-8-7-9-22)20-24(35)18-25-30-17-12-26(31-25)37-3;1-31(2)29(23-10-4-3-5-11-23)16-14-28(15-17-29)21-32(27(36)33(28)19-22-8-6-9-22)20-25(34)18-24-12-7-13-26(35)30-24;1-29(2)26(21-7-5-4-6-8-21)12-10-25(11-13-26)19-30(24(33)31(25)15-16-34-3)18-23(32)17-22-9-14-27-20-28-22;1-27(2)26(22-10-4-3-5-11-22)15-13-25(14-16-26)20-28(19-23(31)12-7-17-30)24(32)29(25)18-21-8-6-9-21;1-4-22(29)18-27-19-24(28(23(27)30)17-20-9-8-10-20)13-15-25(16-14-24,26(2)3)21-11-6-5-7-12-21;1-26(2)24(19-7-5-4-6-8-19)13-11-23(12-14-24)18-27(17-20(29)9-10-21(25)30)22(31)28(23)15-16-32-3;1-25(2)24(20-8-5-4-6-9-20)13-11-23(12-14-24)19-26(18-21(29)10-7-16-28)22(30)27(23)15-17-31-3;1-5-20(27)17-25-18-22(26(21(25)28)15-16-29-4)11-13-23(14-12-22,24(2)3)19-9-7-6-8-10-19/h4-6,10-11,18-19,23H,7-9,12-17,20-22H2,1-3H3;4-6,8,11-14,23H,7,9-10,15-22H2,1-3H3;4-6,10-13,19,23H,7-9,14-18,20-22H2,1-3H3;3-5,9-10,17,21-22H,6-8,11-15,18-20H2,1-2H3;4-6,10-12,17,22H,7-9,13-16,18-21H2,1-3H3;3-5,7,10-13,22H,6,8-9,14-21H2,1-2H3,(H,30,35);4-9,14,20H,10-13,15-19H2,1-3H3;3-5,10-11,21,30H,6-9,12-20H2,1-2H3;5-7,11-12,20H,4,8-10,13-19H2,1-3H3;4-8H,9-18H2,1-3H3,(H2,25,30);4-6,8-9,28H,7,10-19H2,1-3H3;6-10H,5,11-18H2,1-4H3
InChIKeyALYDDVFMVZBNMZ-UHFFFAOYSA-N
MW5654.64 g/mol
LogP44.43
Rot. Bonds106

About 1-(cyclobutylmethyl)-8-(dimethylamino)-3-(5-hydroxy-2-oxopentyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[4-(2-methoxypyrimidin-5-yl)-2-oxobutyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(4-methoxypyrimidin-2-yl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(5-methylsulfanyl-2-pyridinyl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(6-methylsulfanyl-2-pyridinyl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-(2-oxobutyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[2-oxo-3-(6-oxo-1H-pyridin-2-yl)propyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;4-[3-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-2-oxopropyl]pyrimidine-5-carbonitrile;8-(dimethylamino)-3-(5-hydroxy-2-oxopentyl)-1-(2-methoxyethyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-1-(2-methoxyethyl)-3-(2-oxobutyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;5-[8-(dimethylamino)-1-(2-methoxyethyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-oxopentanamide;8-(dimethylamino)-1-(2-methoxyethyl)-3-(2-oxo-3-pyrimidin-4-ylpropyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one

1-(cyclobutylmethyl)-8-(dimethylamino)-3-(5-hydroxy-2-oxopentyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[4-(2-methoxypyrimidin-5-yl)-2-oxobutyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(4-methoxypyrimidin-2-yl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(5-methylsulfanyl-2-pyridinyl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(6-methylsulfanyl-2-pyridinyl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-(2-oxobutyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[2-oxo-3-(6-oxo-1H-pyridin-2-yl)propyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;4-[3-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-2-oxopropyl]pyrimidine-5-carbonitrile;8-(dimethylamino)-3-(5-hydroxy-2-oxopentyl)-1-(2-methoxyethyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-1-(2-methoxyethyl)-3-(2-oxobutyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;5-[8-(dimethylamino)-1-(2-methoxyethyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-oxopentanamide;8-(dimethylamino)-1-(2-methoxyethyl)-3-(2-oxo-3-pyrimidin-4-ylpropyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one (PubChem CID 157157125) has the molecular formula C325H453N49O34S2 and a molecular weight of 5654.64 g/mol. Its IUPAC name is 1-(cyclobutylmethyl)-8-(dimethylamino)-3-(5-hydroxy-2-oxopentyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[4-(2-methoxypyrimidin-5-yl)-2-oxobutyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(4-methoxypyrimidin-2-yl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(5-methylsulfanyl-2-pyridinyl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(6-methylsulfanyl-2-pyridinyl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-(2-oxobutyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[2-oxo-3-(6-oxo-1H-pyridin-2-yl)propyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;4-[3-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-2-oxopropyl]pyrimidine-5-carbonitrile;8-(dimethylamino)-3-(5-hydroxy-2-oxopentyl)-1-(2-methoxyethyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-1-(2-methoxyethyl)-3-(2-oxobutyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;5-[8-(dimethylamino)-1-(2-methoxyethyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-oxopentanamide;8-(dimethylamino)-1-(2-methoxyethyl)-3-(2-oxo-3-pyrimidin-4-ylpropyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one.

Molecular Properties

Compound Name1-(cyclobutylmethyl)-8-(dimethylamino)-3-(5-hydroxy-2-oxopentyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[4-(2-methoxypyrimidin-5-yl)-2-oxobutyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(4-methoxypyrimidin-2-yl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(5-methylsulfanyl-2-pyridinyl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(6-methylsulfanyl-2-pyridinyl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-(2-oxobutyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[2-oxo-3-(6-oxo-1H-pyridin-2-yl)propyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;4-[3-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-2-oxopropyl]pyrimidine-5-carbonitrile;8-(dimethylamino)-3-(5-hydroxy-2-oxopentyl)-1-(2-methoxyethyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-1-(2-methoxyethyl)-3-(2-oxobutyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;5-[8-(dimethylamino)-1-(2-methoxyethyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-oxopentanamide;8-(dimethylamino)-1-(2-methoxyethyl)-3-(2-oxo-3-pyrimidin-4-ylpropyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one
PubChem CID157157125
Molecular FormulaC325H453N49O34S2
Molecular Weight5654.64 g/mol
Exact Mass5650.47
IUPAC Name1-(cyclobutylmethyl)-8-(dimethylamino)-3-(5-hydroxy-2-oxopentyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[4-(2-methoxypyrimidin-5-yl)-2-oxobutyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(4-methoxypyrimidin-2-yl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(5-methylsulfanyl-2-pyridinyl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(6-methylsulfanyl-2-pyridinyl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-(2-oxobutyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[2-oxo-3-(6-oxo-1H-pyridin-2-yl)propyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;4-[3-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-2-oxopropyl]pyrimidine-5-carbonitrile;8-(dimethylamino)-3-(5-hydroxy-2-oxopentyl)-1-(2-methoxyethyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-1-(2-methoxyethyl)-3-(2-oxobutyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;5-[8-(dimethylamino)-1-(2-methoxyethyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-oxopentanamide;8-(dimethylamino)-1-(2-methoxyethyl)-3-(2-oxo-3-pyrimidin-4-ylpropyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one
SMILESCCC(=O)CN1CC2(CCC(c3ccccc3)(N(C)C)CC2)N(CC2CCC2)C1=O.CCC(=O)CN1CC2(CCC(c3ccccc3)(N(C)C)CC2)N(CCOC)C1=O.CN(C)C1(c2ccccc2)CCC2(CC1)CN(CC(=O)CCCO)C(=O)N2CC1CCC1.CN(C)C1(c2ccccc2)CCC2(CC1)CN(CC(=O)Cc1cccc(=O)[nH]1)C(=O)N2CC1CCC1.CN(C)C1(c2ccccc2)CCC2(CC1)CN(CC(=O)Cc1ncncc1C#N)C(=O)N2CC1CCC1.COCCN1C(=O)N(CC(=O)CCC(N)=O)CC12CCC(c1ccccc1)(N(C)C)CC2.COCCN1C(=O)N(CC(=O)CCCO)CC12CCC(c1ccccc1)(N(C)C)CC2.COCCN1C(=O)N(CC(=O)Cc2ccncn2)CC12CCC(c1ccccc1)(N(C)C)CC2.COc1ccnc(CC(=O)CN2CC3(CCC(c4ccccc4)(N(C)C)CC3)N(CC3CCC3)C2=O)n1.COc1ncc(CCC(=O)CN2CC3(CCC(c4ccccc4)(N(C)C)CC3)N(CC3CCC3)C2=O)cn1.CSc1ccc(CC(=O)CN2CC3(CCC(c4ccccc4)(N(C)C)CC3)N(CC3CCC3)C2=O)nc1.CSc1cccc(CC(=O)CN2CC3(CCC(c4ccccc4)(N(C)C)CC3)N(CC3CCC3)C2=O)n1
InChIInChI=1S/C30H41N5O3.2C30H40N4O2S.C29H36N6O2.C29H39N5O3.C29H38N4O3.C26H35N5O3.C26H39N3O3.C25H37N3O2.C24H36N4O4.C24H37N3O4.C23H35N3O3/c1-33(2)30(25-10-5-4-6-11-25)16-14-29(15-17-30)22-34(28(37)35(29)20-23-8-7-9-23)21-26(36)13-12-24-18-31-27(38-3)32-19-24;1-32(2)30(24-11-5-4-6-12-24)17-15-29(16-18-30)22-33(28(36)34(29)20-23-9-7-10-23)21-26(35)19-25-13-8-14-27(31-25)37-3;1-32(2)30(24-10-5-4-6-11-24)16-14-29(15-17-30)22-33(28(36)34(29)20-23-8-7-9-23)21-26(35)18-25-12-13-27(37-3)19-31-25;1-33(2)29(24-9-4-3-5-10-24)13-11-28(12-14-29)20-34(27(37)35(28)18-22-7-6-8-22)19-25(36)15-26-23(16-30)17-31-21-32-26;1-32(2)29(23-10-5-4-6-11-23)15-13-28(14-16-29)21-33(27(36)34(28)19-22-8-7-9-22)20-24(35)18-25-30-17-12-26(31-25)37-3;1-31(2)29(23-10-4-3-5-11-23)16-14-28(15-17-29)21-32(27(36)33(28)19-22-8-6-9-22)20-25(34)18-24-12-7-13-26(35)30-24;1-29(2)26(21-7-5-4-6-8-21)12-10-25(11-13-26)19-30(24(33)31(25)15-16-34-3)18-23(32)17-22-9-14-27-20-28-22;1-27(2)26(22-10-4-3-5-11-22)15-13-25(14-16-26)20-28(19-23(31)12-7-17-30)24(32)29(25)18-21-8-6-9-21;1-4-22(29)18-27-19-24(28(23(27)30)17-20-9-8-10-20)13-15-25(16-14-24,26(2)3)21-11-6-5-7-12-21;1-26(2)24(19-7-5-4-6-8-19)13-11-23(12-14-24)18-27(17-20(29)9-10-21(25)30)22(31)28(23)15-16-32-3;1-25(2)24(20-8-5-4-6-9-20)13-11-23(12-14-24)19-26(18-21(29)10-7-16-28)22(30)27(23)15-17-31-3;1-5-20(27)17-25-18-22(26(21(25)28)15-16-29-4)11-13-23(14-12-22,24(2)3)19-9-7-6-8-10-19/h4-6,10-11,18-19,23H,7-9,12-17,20-22H2,1-3H3;4-6,8,11-14,23H,7,9-10,15-22H2,1-3H3;4-6,10-13,19,23H,7-9,14-18,20-22H2,1-3H3;3-5,9-10,17,21-22H,6-8,11-15,18-20H2,1-2H3;4-6,10-12,17,22H,7-9,13-16,18-21H2,1-3H3;3-5,7,10-13,22H,6,8-9,14-21H2,1-2H3,(H,30,35);4-9,14,20H,10-13,15-19H2,1-3H3;3-5,10-11,21,30H,6-9,12-20H2,1-2H3;5-7,11-12,20H,4,8-10,13-19H2,1-3H3;4-8H,9-18H2,1-3H3,(H2,25,30);4-6,8-9,28H,7,10-19H2,1-3H3;6-10H,5,11-18H2,1-4H3
InChIKeyALYDDVFMVZBNMZ-UHFFFAOYSA-N
XLogP44.43
TPSA850.80 Ų
H-Bond Donors4
H-Bond Acceptors59
Rotatable Bonds106
Heavy Atoms410
Complexity—

Lipinski Rule of Five

3 violations

RuleValue
MW ≤ 5005654.64
LogP ≤ 544.43
H-Bond Donors ≤ 54
H-Bond Acceptors ≤ 1059

Analyze 1-(cyclobutylmethyl)-8-(dimethylamino)-3-(5-hydroxy-2-oxopentyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[4-(2-methoxypyrimidin-5-yl)-2-oxobutyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(4-methoxypyrimidin-2-yl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(5-methylsulfanyl-2-pyridinyl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(6-methylsulfanyl-2-pyridinyl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-(2-oxobutyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[2-oxo-3-(6-oxo-1H-pyridin-2-yl)propyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;4-[3-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-2-oxopropyl]pyrimidine-5-carbonitrile;8-(dimethylamino)-3-(5-hydroxy-2-oxopentyl)-1-(2-methoxyethyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-1-(2-methoxyethyl)-3-(2-oxobutyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;5-[8-(dimethylamino)-1-(2-methoxyethyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-oxopentanamide;8-(dimethylamino)-1-(2-methoxyethyl)-3-(2-oxo-3-pyrimidin-4-ylpropyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one with MolForge

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Frequently Asked Questions

What is the IUPAC name of 1-(cyclobutylmethyl)-8-(dimethylamino)-3-(5-hydroxy-2-oxopentyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[4-(2-methoxypyrimidin-5-yl)-2-oxobutyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(4-methoxypyrimidin-2-yl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(5-methylsulfanyl-2-pyridinyl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(6-methylsulfanyl-2-pyridinyl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-(2-oxobutyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[2-oxo-3-(6-oxo-1H-pyridin-2-yl)propyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;4-[3-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-2-oxopropyl]pyrimidine-5-carbonitrile;8-(dimethylamino)-3-(5-hydroxy-2-oxopentyl)-1-(2-methoxyethyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-1-(2-methoxyethyl)-3-(2-oxobutyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;5-[8-(dimethylamino)-1-(2-methoxyethyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-oxopentanamide;8-(dimethylamino)-1-(2-methoxyethyl)-3-(2-oxo-3-pyrimidin-4-ylpropyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one?
The IUPAC name of 1-(cyclobutylmethyl)-8-(dimethylamino)-3-(5-hydroxy-2-oxopentyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[4-(2-methoxypyrimidin-5-yl)-2-oxobutyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(4-methoxypyrimidin-2-yl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(5-methylsulfanyl-2-pyridinyl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(6-methylsulfanyl-2-pyridinyl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-(2-oxobutyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[2-oxo-3-(6-oxo-1H-pyridin-2-yl)propyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;4-[3-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-2-oxopropyl]pyrimidine-5-carbonitrile;8-(dimethylamino)-3-(5-hydroxy-2-oxopentyl)-1-(2-methoxyethyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-1-(2-methoxyethyl)-3-(2-oxobutyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;5-[8-(dimethylamino)-1-(2-methoxyethyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-oxopentanamide;8-(dimethylamino)-1-(2-methoxyethyl)-3-(2-oxo-3-pyrimidin-4-ylpropyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one (CID 157157125) is 1-(cyclobutylmethyl)-8-(dimethylamino)-3-(5-hydroxy-2-oxopentyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[4-(2-methoxypyrimidin-5-yl)-2-oxobutyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(4-methoxypyrimidin-2-yl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(5-methylsulfanyl-2-pyridinyl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(6-methylsulfanyl-2-pyridinyl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-(2-oxobutyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[2-oxo-3-(6-oxo-1H-pyridin-2-yl)propyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;4-[3-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-2-oxopropyl]pyrimidine-5-carbonitrile;8-(dimethylamino)-3-(5-hydroxy-2-oxopentyl)-1-(2-methoxyethyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-1-(2-methoxyethyl)-3-(2-oxobutyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;5-[8-(dimethylamino)-1-(2-methoxyethyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-oxopentanamide;8-(dimethylamino)-1-(2-methoxyethyl)-3-(2-oxo-3-pyrimidin-4-ylpropyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one.
What is the SMILES notation for 1-(cyclobutylmethyl)-8-(dimethylamino)-3-(5-hydroxy-2-oxopentyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[4-(2-methoxypyrimidin-5-yl)-2-oxobutyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(4-methoxypyrimidin-2-yl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(5-methylsulfanyl-2-pyridinyl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(6-methylsulfanyl-2-pyridinyl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-(2-oxobutyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[2-oxo-3-(6-oxo-1H-pyridin-2-yl)propyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;4-[3-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-2-oxopropyl]pyrimidine-5-carbonitrile;8-(dimethylamino)-3-(5-hydroxy-2-oxopentyl)-1-(2-methoxyethyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-1-(2-methoxyethyl)-3-(2-oxobutyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;5-[8-(dimethylamino)-1-(2-methoxyethyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-oxopentanamide;8-(dimethylamino)-1-(2-methoxyethyl)-3-(2-oxo-3-pyrimidin-4-ylpropyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one?
The canonical SMILES for 1-(cyclobutylmethyl)-8-(dimethylamino)-3-(5-hydroxy-2-oxopentyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[4-(2-methoxypyrimidin-5-yl)-2-oxobutyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(4-methoxypyrimidin-2-yl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(5-methylsulfanyl-2-pyridinyl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(6-methylsulfanyl-2-pyridinyl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-(2-oxobutyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[2-oxo-3-(6-oxo-1H-pyridin-2-yl)propyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;4-[3-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-2-oxopropyl]pyrimidine-5-carbonitrile;8-(dimethylamino)-3-(5-hydroxy-2-oxopentyl)-1-(2-methoxyethyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-1-(2-methoxyethyl)-3-(2-oxobutyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;5-[8-(dimethylamino)-1-(2-methoxyethyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-oxopentanamide;8-(dimethylamino)-1-(2-methoxyethyl)-3-(2-oxo-3-pyrimidin-4-ylpropyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one is CCC(=O)CN1CC2(CCC(c3ccccc3)(N(C)C)CC2)N(CC2CCC2)C1=O.CCC(=O)CN1CC2(CCC(c3ccccc3)(N(C)C)CC2)N(CCOC)C1=O.CN(C)C1(c2ccccc2)CCC2(CC1)CN(CC(=O)CCCO)C(=O)N2CC1CCC1.CN(C)C1(c2ccccc2)CCC2(CC1)CN(CC(=O)Cc1cccc(=O)[nH]1)C(=O)N2CC1CCC1.CN(C)C1(c2ccccc2)CCC2(CC1)CN(CC(=O)Cc1ncncc1C#N)C(=O)N2CC1CCC1.COCCN1C(=O)N(CC(=O)CCC(N)=O)CC12CCC(c1ccccc1)(N(C)C)CC2.COCCN1C(=O)N(CC(=O)CCCO)CC12CCC(c1ccccc1)(N(C)C)CC2.COCCN1C(=O)N(CC(=O)Cc2ccncn2)CC12CCC(c1ccccc1)(N(C)C)CC2.COc1ccnc(CC(=O)CN2CC3(CCC(c4ccccc4)(N(C)C)CC3)N(CC3CCC3)C2=O)n1.COc1ncc(CCC(=O)CN2CC3(CCC(c4ccccc4)(N(C)C)CC3)N(CC3CCC3)C2=O)cn1.CSc1ccc(CC(=O)CN2CC3(CCC(c4ccccc4)(N(C)C)CC3)N(CC3CCC3)C2=O)nc1.CSc1cccc(CC(=O)CN2CC3(CCC(c4ccccc4)(N(C)C)CC3)N(CC3CCC3)C2=O)n1.
What is the InChIKey of 1-(cyclobutylmethyl)-8-(dimethylamino)-3-(5-hydroxy-2-oxopentyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[4-(2-methoxypyrimidin-5-yl)-2-oxobutyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(4-methoxypyrimidin-2-yl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(5-methylsulfanyl-2-pyridinyl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(6-methylsulfanyl-2-pyridinyl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-(2-oxobutyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[2-oxo-3-(6-oxo-1H-pyridin-2-yl)propyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;4-[3-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-2-oxopropyl]pyrimidine-5-carbonitrile;8-(dimethylamino)-3-(5-hydroxy-2-oxopentyl)-1-(2-methoxyethyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-1-(2-methoxyethyl)-3-(2-oxobutyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;5-[8-(dimethylamino)-1-(2-methoxyethyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-oxopentanamide;8-(dimethylamino)-1-(2-methoxyethyl)-3-(2-oxo-3-pyrimidin-4-ylpropyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one?
The InChIKey is ALYDDVFMVZBNMZ-UHFFFAOYSA-N. The full InChI is InChI=1S/C30H41N5O3.2C30H40N4O2S.C29H36N6O2.C29H39N5O3.C29H38N4O3.C26H35N5O3.C26H39N3O3.C25H37N3O2.C24H36N4O4.C24H37N3O4.C23H35N3O3/c1-33(2)30(25-10-5-4-6-11-25)16-14-29(15-17-30)22-34(28(37)35(29)20-23-8-7-9-23)21-26(36)13-12-24-18-31-27(38-3)32-19-24;1-32(2)30(24-11-5-4-6-12-24)17-15-29(16-18-30)22-33(28(36)34(29)20-23-9-7-10-23)21-26(35)19-25-13-8-14-27(31-25)37-3;1-32(2)30(24-10-5-4-6-11-24)16-14-29(15-17-30)22-33(28(36)34(29)20-23-8-7-9-23)21-26(35)18-25-12-13-27(37-3)19-31-25;1-33(2)29(24-9-4-3-5-10-24)13-11-28(12-14-29)20-34(27(37)35(28)18-22-7-6-8-22)19-25(36)15-26-23(16-30)17-31-21-32-26;1-32(2)29(23-10-5-4-6-11-23)15-13-28(14-16-29)21-33(27(36)34(28)19-22-8-7-9-22)20-24(35)18-25-30-17-12-26(31-25)37-3;1-31(2)29(23-10-4-3-5-11-23)16-14-28(15-17-29)21-32(27(36)33(28)19-22-8-6-9-22)20-25(34)18-24-12-7-13-26(35)30-24;1-29(2)26(21-7-5-4-6-8-21)12-10-25(11-13-26)19-30(24(33)31(25)15-16-34-3)18-23(32)17-22-9-14-27-20-28-22;1-27(2)26(22-10-4-3-5-11-22)15-13-25(14-16-26)20-28(19-23(31)12-7-17-30)24(32)29(25)18-21-8-6-9-21;1-4-22(29)18-27-19-24(28(23(27)30)17-20-9-8-10-20)13-15-25(16-14-24,26(2)3)21-11-6-5-7-12-21;1-26(2)24(19-7-5-4-6-8-19)13-11-23(12-14-24)18-27(17-20(29)9-10-21(25)30)22(31)28(23)15-16-32-3;1-25(2)24(20-8-5-4-6-9-20)13-11-23(12-14-24)19-26(18-21(29)10-7-16-28)22(30)27(23)15-17-31-3;1-5-20(27)17-25-18-22(26(21(25)28)15-16-29-4)11-13-23(14-12-22,24(2)3)19-9-7-6-8-10-19/h4-6,10-11,18-19,23H,7-9,12-17,20-22H2,1-3H3;4-6,8,11-14,23H,7,9-10,15-22H2,1-3H3;4-6,10-13,19,23H,7-9,14-18,20-22H2,1-3H3;3-5,9-10,17,21-22H,6-8,11-15,18-20H2,1-2H3;4-6,10-12,17,22H,7-9,13-16,18-21H2,1-3H3;3-5,7,10-13,22H,6,8-9,14-21H2,1-2H3,(H,30,35);4-9,14,20H,10-13,15-19H2,1-3H3;3-5,10-11,21,30H,6-9,12-20H2,1-2H3;5-7,11-12,20H,4,8-10,13-19H2,1-3H3;4-8H,9-18H2,1-3H3,(H2,25,30);4-6,8-9,28H,7,10-19H2,1-3H3;6-10H,5,11-18H2,1-4H3.
What are the key properties of 1-(cyclobutylmethyl)-8-(dimethylamino)-3-(5-hydroxy-2-oxopentyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[4-(2-methoxypyrimidin-5-yl)-2-oxobutyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(4-methoxypyrimidin-2-yl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(5-methylsulfanyl-2-pyridinyl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(6-methylsulfanyl-2-pyridinyl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-(2-oxobutyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[2-oxo-3-(6-oxo-1H-pyridin-2-yl)propyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;4-[3-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-2-oxopropyl]pyrimidine-5-carbonitrile;8-(dimethylamino)-3-(5-hydroxy-2-oxopentyl)-1-(2-methoxyethyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-1-(2-methoxyethyl)-3-(2-oxobutyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;5-[8-(dimethylamino)-1-(2-methoxyethyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-oxopentanamide;8-(dimethylamino)-1-(2-methoxyethyl)-3-(2-oxo-3-pyrimidin-4-ylpropyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one?
1-(cyclobutylmethyl)-8-(dimethylamino)-3-(5-hydroxy-2-oxopentyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[4-(2-methoxypyrimidin-5-yl)-2-oxobutyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(4-methoxypyrimidin-2-yl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(5-methylsulfanyl-2-pyridinyl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(6-methylsulfanyl-2-pyridinyl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-(2-oxobutyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[2-oxo-3-(6-oxo-1H-pyridin-2-yl)propyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;4-[3-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-2-oxopropyl]pyrimidine-5-carbonitrile;8-(dimethylamino)-3-(5-hydroxy-2-oxopentyl)-1-(2-methoxyethyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-1-(2-methoxyethyl)-3-(2-oxobutyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;5-[8-(dimethylamino)-1-(2-methoxyethyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-oxopentanamide;8-(dimethylamino)-1-(2-methoxyethyl)-3-(2-oxo-3-pyrimidin-4-ylpropyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one has a molecular weight of 5654.64 g/mol, XLogP of 44.43, 106 rotatable bonds, 4 hydrogen bond donors, and 59 hydrogen bond acceptors.
Where does this data come from?
All data for 1-(cyclobutylmethyl)-8-(dimethylamino)-3-(5-hydroxy-2-oxopentyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[4-(2-methoxypyrimidin-5-yl)-2-oxobutyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(4-methoxypyrimidin-2-yl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(5-methylsulfanyl-2-pyridinyl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(6-methylsulfanyl-2-pyridinyl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-(2-oxobutyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[2-oxo-3-(6-oxo-1H-pyridin-2-yl)propyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;4-[3-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-2-oxopropyl]pyrimidine-5-carbonitrile;8-(dimethylamino)-3-(5-hydroxy-2-oxopentyl)-1-(2-methoxyethyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-1-(2-methoxyethyl)-3-(2-oxobutyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;5-[8-(dimethylamino)-1-(2-methoxyethyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-oxopentanamide;8-(dimethylamino)-1-(2-methoxyethyl)-3-(2-oxo-3-pyrimidin-4-ylpropyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one is sourced from PubChem (CID 157157125), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).