3-amino-N-[2-(5-chloro-6-piperidin-1-yl-3-pyridinyl)ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-6-cyano-N-[2-(2,5-difluoro-4-piperidin-1-ylphenyl)ethyl]thieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-[4-[(5S)-2,9-diazaspiro[4.5]decan-2-yl]phenyl]ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-[4-[(5R)-2,9-diazaspiro[4.5]decan-2-yl]phenyl]ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-6-methyl-N-[2-[4-[[(7R)-5-oxaspiro[3.4]octan-7-yl]oxy]phenyl]ethyl]thieno[2,3-b]pyridine-2-carboxamide;3-amino-6-methyl-N-[2-[4-[[(7S)-5-oxaspiro[3.4]octan-7-yl]oxy]phenyl]ethyl]thieno[2,3-b]pyridine-2-carboxamide

C141H161ClF2N26O10S6 — CID 157159279

About 3-amino-N-[2-(5-chloro-6-piperidin-1-yl-3-pyridinyl)ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-6-cyano-N-[2-(2,5-difluoro-4-piperidin-1-ylphenyl)ethyl]thieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-[4-[(5S)-2,9-diazaspiro[4.5]decan-2-yl]phenyl]ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-[4-[(5R)-2,9-diazaspiro[4.5]decan-2-yl]phenyl]ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-6-methyl-N-[2-[4-[[(7R)-5-oxaspiro[3.4]octan-7-yl]oxy]phenyl]ethyl]thieno[2,3-b]pyridine-2-carboxamide;3-amino-6-methyl-N-[2-[4-[[(7S)-5-oxaspiro[3.4]octan-7-yl]oxy]phenyl]ethyl]thieno[2,3-b]pyridine-2-carboxamide

3-amino-N-[2-(5-chloro-6-piperidin-1-yl-3-pyridinyl)ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-6-cyano-N-[2-(2,5-difluoro-4-piperidin-1-ylphenyl)ethyl]thieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-[4-[(5S)-2,9-diazaspiro[4.5]decan-2-yl]phenyl]ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-[4-[(5R)-2,9-diazaspiro[4.5]decan-2-yl]phenyl]ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-6-methyl-N-[2-[4-[[(7R)-5-oxaspiro[3.4]octan-7-yl]oxy]phenyl]ethyl]thieno[2,3-b]pyridine-2-carboxamide;3-amino-6-methyl-N-[2-[4-[[(7S)-5-oxaspiro[3.4]octan-7-yl]oxy]phenyl]ethyl]thieno[2,3-b]pyridine-2-carboxamide (PubChem CID 157159279) has the molecular formula C141H161ClF2N26O10S6 and a molecular weight of 2645.86 g/mol. Its IUPAC name is 3-amino-N-[2-(5-chloro-6-piperidin-1-yl-3-pyridinyl)ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-6-cyano-N-[2-(2,5-difluoro-4-piperidin-1-ylphenyl)ethyl]thieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-[4-[(5S)-2,9-diazaspiro[4.5]decan-2-yl]phenyl]ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-[4-[(5R)-2,9-diazaspiro[4.5]decan-2-yl]phenyl]ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-6-methyl-N-[2-[4-[[(7R)-5-oxaspiro[3.4]octan-7-yl]oxy]phenyl]ethyl]thieno[2,3-b]pyridine-2-carboxamide;3-amino-6-methyl-N-[2-[4-[[(7S)-5-oxaspiro[3.4]octan-7-yl]oxy]phenyl]ethyl]thieno[2,3-b]pyridine-2-carboxamide.

Molecular Properties

• Compound Name: 3-amino-N-[2-(5-chloro-6-piperidin-1-yl-3-pyridinyl)ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-6-cyano-N-[2-(2,5-difluoro-4-piperidin-1-ylphenyl)ethyl]thieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-[4-[(5S)-2,9-diazaspiro[4.5]decan-2-yl]phenyl]ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-[4-[(5R)-2,9-diazaspiro[4.5]decan-2-yl]phenyl]ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-6-methyl-N-[2-[4-[[(7R)-5-oxaspiro[3.4]octan-7-yl]oxy]phenyl]ethyl]thieno[2,3-b]pyridine-2-carboxamide;3-amino-6-methyl-N-[2-[4-[[(7S)-5-oxaspiro[3.4]octan-7-yl]oxy]phenyl]ethyl]thieno[2,3-b]pyridine-2-carboxamide
• PubChem CID: 157159279
• Molecular Formula: C141H161ClF2N26O10S6
• Molecular Weight: 2645.86 g/mol
• Exact Mass: 2643.09
• IUPAC Name: 3-amino-N-[2-(5-chloro-6-piperidin-1-yl-3-pyridinyl)ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-6-cyano-N-[2-(2,5-difluoro-4-piperidin-1-ylphenyl)ethyl]thieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-[4-[(5S)-2,9-diazaspiro[4.5]decan-2-yl]phenyl]ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-[4-[(5R)-2,9-diazaspiro[4.5]decan-2-yl]phenyl]ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-6-methyl-N-[2-[4-[[(7R)-5-oxaspiro[3.4]octan-7-yl]oxy]phenyl]ethyl]thieno[2,3-b]pyridine-2-carboxamide;3-amino-6-methyl-N-[2-[4-[[(7S)-5-oxaspiro[3.4]octan-7-yl]oxy]phenyl]ethyl]thieno[2,3-b]pyridine-2-carboxamide
• SMILES: Cc1ccc2c(N)c(C(=O)NCCc3ccc(N4CC[C@@]5(CCCNC5)C4)cc3)sc2n1.Cc1ccc2c(N)c(C(=O)NCCc3ccc(N4CC[C@]5(CCCNC5)C4)cc3)sc2n1.Cc1ccc2c(N)c(C(=O)NCCc3ccc(O[C@@H]4COC5(CCC5)C4)cc3)sc2n1.Cc1ccc2c(N)c(C(=O)NCCc3ccc(O[C@H]4COC5(CCC5)C4)cc3)sc2n1.Cc1ccc2c(N)c(C(=O)NCCc3cnc(N4CCCCC4)c(Cl)c3)sc2n1.N#Cc1ccc2c(N)c(C(=O)NCCc3cc(F)c(N4CCCCC4)cc3F)sc2n1
• InChI: InChI=1S/2C25H31N5OS.2C24H27N3O3S.C22H21F2N5OS.C21H24ClN5OS/c2*1-17-3-8-20-21(26)22(32-24(20)29-17)23(31)28-13-9-18-4-6-19(7-5-18)30-14-11-25(16-30)10-2-12-27-15-25;2*1-15-3-8-19-20(25)21(31-23(19)27-15)22(28)26-12-9-16-4-6-17(7-5-16)30-18-13-24(29-14-18)10-2-11-24;23-16-11-18(29-8-2-1-3-9-29)17(24)10-13(16)6-7-27-21(30)20-19(26)15-5-4-14(12-25)28-22(15)31-20;1-13-5-6-15-17(23)18(29-21(15)26-13)20(28)24-8-7-14-11-16(22)19(25-12-14)27-9-3-2-4-10-27/h2*3-8,27H,2,9-16,26H2,1H3,(H,28,31);2*3-8,18H,2,9-14,25H2,1H3,(H,26,28);4-5,10-11H,1-3,6-9,26H2,(H,27,30);5-6,11-12H,2-4,7-10,23H2,1H3,(H,24,28)/t2*25-;2*18-;;/m1010../s1
• InChIKey: AMEISBONLDCKRN-NFKWVMJWSA-N
• XLogP: 24.17
• TPSA: 518.68 Ų
• H-Bond Donors: 14
• H-Bond Acceptors: 36
• Rotatable Bonds: 32
• Heavy Atoms: 186
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2645.86
LogP ≤ 5	24.17
H-Bond Donors ≤ 5	14
H-Bond Acceptors ≤ 10	36

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': 'anil_di_alk_E(186)', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of 3-amino-N-[2-(5-chloro-6-piperidin-1-yl-3-pyridinyl)ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-6-cyano-N-[2-(2,5-difluoro-4-piperidin-1-ylphenyl)ethyl]thieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-[4-[(5S)-2,9-diazaspiro[4.5]decan-2-yl]phenyl]ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-[4-[(5R)-2,9-diazaspiro[4.5]decan-2-yl]phenyl]ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-6-methyl-N-[2-[4-[[(7R)-5-oxaspiro[3.4]octan-7-yl]oxy]phenyl]ethyl]thieno[2,3-b]pyridine-2-carboxamide;3-amino-6-methyl-N-[2-[4-[[(7S)-5-oxaspiro[3.4]octan-7-yl]oxy]phenyl]ethyl]thieno[2,3-b]pyridine-2-carboxamide?

The IUPAC name of 3-amino-N-[2-(5-chloro-6-piperidin-1-yl-3-pyridinyl)ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-6-cyano-N-[2-(2,5-difluoro-4-piperidin-1-ylphenyl)ethyl]thieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-[4-[(5S)-2,9-diazaspiro[4.5]decan-2-yl]phenyl]ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-[4-[(5R)-2,9-diazaspiro[4.5]decan-2-yl]phenyl]ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-6-methyl-N-[2-[4-[[(7R)-5-oxaspiro[3.4]octan-7-yl]oxy]phenyl]ethyl]thieno[2,3-b]pyridine-2-carboxamide;3-amino-6-methyl-N-[2-[4-[[(7S)-5-oxaspiro[3.4]octan-7-yl]oxy]phenyl]ethyl]thieno[2,3-b]pyridine-2-carboxamide (CID 157159279) is 3-amino-N-[2-(5-chloro-6-piperidin-1-yl-3-pyridinyl)ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-6-cyano-N-[2-(2,5-difluoro-4-piperidin-1-ylphenyl)ethyl]thieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-[4-[(5S)-2,9-diazaspiro[4.5]decan-2-yl]phenyl]ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-[4-[(5R)-2,9-diazaspiro[4.5]decan-2-yl]phenyl]ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-6-methyl-N-[2-[4-[[(7R)-5-oxaspiro[3.4]octan-7-yl]oxy]phenyl]ethyl]thieno[2,3-b]pyridine-2-carboxamide;3-amino-6-methyl-N-[2-[4-[[(7S)-5-oxaspiro[3.4]octan-7-yl]oxy]phenyl]ethyl]thieno[2,3-b]pyridine-2-carboxamide.

What is the SMILES notation for 3-amino-N-[2-(5-chloro-6-piperidin-1-yl-3-pyridinyl)ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-6-cyano-N-[2-(2,5-difluoro-4-piperidin-1-ylphenyl)ethyl]thieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-[4-[(5S)-2,9-diazaspiro[4.5]decan-2-yl]phenyl]ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-[4-[(5R)-2,9-diazaspiro[4.5]decan-2-yl]phenyl]ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-6-methyl-N-[2-[4-[[(7R)-5-oxaspiro[3.4]octan-7-yl]oxy]phenyl]ethyl]thieno[2,3-b]pyridine-2-carboxamide;3-amino-6-methyl-N-[2-[4-[[(7S)-5-oxaspiro[3.4]octan-7-yl]oxy]phenyl]ethyl]thieno[2,3-b]pyridine-2-carboxamide?

The canonical SMILES for 3-amino-N-[2-(5-chloro-6-piperidin-1-yl-3-pyridinyl)ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-6-cyano-N-[2-(2,5-difluoro-4-piperidin-1-ylphenyl)ethyl]thieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-[4-[(5S)-2,9-diazaspiro[4.5]decan-2-yl]phenyl]ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-[4-[(5R)-2,9-diazaspiro[4.5]decan-2-yl]phenyl]ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-6-methyl-N-[2-[4-[[(7R)-5-oxaspiro[3.4]octan-7-yl]oxy]phenyl]ethyl]thieno[2,3-b]pyridine-2-carboxamide;3-amino-6-methyl-N-[2-[4-[[(7S)-5-oxaspiro[3.4]octan-7-yl]oxy]phenyl]ethyl]thieno[2,3-b]pyridine-2-carboxamide is Cc1ccc2c(N)c(C(=O)NCCc3ccc(N4CC[C@@]5(CCCNC5)C4)cc3)sc2n1.Cc1ccc2c(N)c(C(=O)NCCc3ccc(N4CC[C@]5(CCCNC5)C4)cc3)sc2n1.Cc1ccc2c(N)c(C(=O)NCCc3ccc(O[C@@H]4COC5(CCC5)C4)cc3)sc2n1.Cc1ccc2c(N)c(C(=O)NCCc3ccc(O[C@H]4COC5(CCC5)C4)cc3)sc2n1.Cc1ccc2c(N)c(C(=O)NCCc3cnc(N4CCCCC4)c(Cl)c3)sc2n1.N#Cc1ccc2c(N)c(C(=O)NCCc3cc(F)c(N4CCCCC4)cc3F)sc2n1.

What is the InChIKey of 3-amino-N-[2-(5-chloro-6-piperidin-1-yl-3-pyridinyl)ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-6-cyano-N-[2-(2,5-difluoro-4-piperidin-1-ylphenyl)ethyl]thieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-[4-[(5S)-2,9-diazaspiro[4.5]decan-2-yl]phenyl]ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-[4-[(5R)-2,9-diazaspiro[4.5]decan-2-yl]phenyl]ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-6-methyl-N-[2-[4-[[(7R)-5-oxaspiro[3.4]octan-7-yl]oxy]phenyl]ethyl]thieno[2,3-b]pyridine-2-carboxamide;3-amino-6-methyl-N-[2-[4-[[(7S)-5-oxaspiro[3.4]octan-7-yl]oxy]phenyl]ethyl]thieno[2,3-b]pyridine-2-carboxamide?

The InChIKey is AMEISBONLDCKRN-NFKWVMJWSA-N. The full InChI is InChI=1S/2C25H31N5OS.2C24H27N3O3S.C22H21F2N5OS.C21H24ClN5OS/c2*1-17-3-8-20-21(26)22(32-24(20)29-17)23(31)28-13-9-18-4-6-19(7-5-18)30-14-11-25(16-30)10-2-12-27-15-25;2*1-15-3-8-19-20(25)21(31-23(19)27-15)22(28)26-12-9-16-4-6-17(7-5-16)30-18-13-24(29-14-18)10-2-11-24;23-16-11-18(29-8-2-1-3-9-29)17(24)10-13(16)6-7-27-21(30)20-19(26)15-5-4-14(12-25)28-22(15)31-20;1-13-5-6-15-17(23)18(29-21(15)26-13)20(28)24-8-7-14-11-16(22)19(25-12-14)27-9-3-2-4-10-27/h2*3-8,27H,2,9-16,26H2,1H3,(H,28,31);2*3-8,18H,2,9-14,25H2,1H3,(H,26,28);4-5,10-11H,1-3,6-9,26H2,(H,27,30);5-6,11-12H,2-4,7-10,23H2,1H3,(H,24,28)/t2*25-;2*18-;;/m1010../s1.

What are the key properties of 3-amino-N-[2-(5-chloro-6-piperidin-1-yl-3-pyridinyl)ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-6-cyano-N-[2-(2,5-difluoro-4-piperidin-1-ylphenyl)ethyl]thieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-[4-[(5S)-2,9-diazaspiro[4.5]decan-2-yl]phenyl]ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-[4-[(5R)-2,9-diazaspiro[4.5]decan-2-yl]phenyl]ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-6-methyl-N-[2-[4-[[(7R)-5-oxaspiro[3.4]octan-7-yl]oxy]phenyl]ethyl]thieno[2,3-b]pyridine-2-carboxamide;3-amino-6-methyl-N-[2-[4-[[(7S)-5-oxaspiro[3.4]octan-7-yl]oxy]phenyl]ethyl]thieno[2,3-b]pyridine-2-carboxamide?

3-amino-N-[2-(5-chloro-6-piperidin-1-yl-3-pyridinyl)ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-6-cyano-N-[2-(2,5-difluoro-4-piperidin-1-ylphenyl)ethyl]thieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-[4-[(5S)-2,9-diazaspiro[4.5]decan-2-yl]phenyl]ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-[4-[(5R)-2,9-diazaspiro[4.5]decan-2-yl]phenyl]ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-6-methyl-N-[2-[4-[[(7R)-5-oxaspiro[3.4]octan-7-yl]oxy]phenyl]ethyl]thieno[2,3-b]pyridine-2-carboxamide;3-amino-6-methyl-N-[2-[4-[[(7S)-5-oxaspiro[3.4]octan-7-yl]oxy]phenyl]ethyl]thieno[2,3-b]pyridine-2-carboxamide has a molecular weight of 2645.86 g/mol, XLogP of 24.17, 32 rotatable bonds, 14 hydrogen bond donors, and 36 hydrogen bond acceptors.

Where does this data come from?

All data for 3-amino-N-[2-(5-chloro-6-piperidin-1-yl-3-pyridinyl)ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-6-cyano-N-[2-(2,5-difluoro-4-piperidin-1-ylphenyl)ethyl]thieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-[4-[(5S)-2,9-diazaspiro[4.5]decan-2-yl]phenyl]ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-[4-[(5R)-2,9-diazaspiro[4.5]decan-2-yl]phenyl]ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-6-methyl-N-[2-[4-[[(7R)-5-oxaspiro[3.4]octan-7-yl]oxy]phenyl]ethyl]thieno[2,3-b]pyridine-2-carboxamide;3-amino-6-methyl-N-[2-[4-[[(7S)-5-oxaspiro[3.4]octan-7-yl]oxy]phenyl]ethyl]thieno[2,3-b]pyridine-2-carboxamide is sourced from PubChem (CID 157159279), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).