(3R,4R)-4-(cyclohexylamino)-1-(5-methyl-3-pyrimidin-2-yl-2-pyridinyl)piperidin-3-ol;[4-(cyclohexylamino)-1-(5-methyl-3-pyrimidin-2-yl-2-pyridinyl)piperidin-3-yl]methanol;N-(2-fluorocyclohexyl)-3-methoxy-1-[6-methyl-3-(3-methyl-1,2,4-oxadiazol-5-yl)quinolin-2-yl]piperidin-4-amine;1-[6-methyl-3-(3-methyl-1,2,4-oxadiazol-5-yl)quinolin-2-yl]-N-(oxan-3-yl)piperidin-4-amine;2-[[1-[6-methyl-3-(3-methyl-1,2,4-oxadiazol-5-yl)quinolin-2-yl]piperidin-4-yl]amino]cyclohexan-1-ol;4-[[1-[6-methyl-3-(3-methyl-1,2,4-oxadiazol-5-yl)quinolin-2-yl]piperidin-4-yl]amino]cyclohexan-1-ol

C139H183FN30O10 — CID 157180679

About (3R,4R)-4-(cyclohexylamino)-1-(5-methyl-3-pyrimidin-2-yl-2-pyridinyl)piperidin-3-ol;[4-(cyclohexylamino)-1-(5-methyl-3-pyrimidin-2-yl-2-pyridinyl)piperidin-3-yl]methanol;N-(2-fluorocyclohexyl)-3-methoxy-1-[6-methyl-3-(3-methyl-1,2,4-oxadiazol-5-yl)quinolin-2-yl]piperidin-4-amine;1-[6-methyl-3-(3-methyl-1,2,4-oxadiazol-5-yl)quinolin-2-yl]-N-(oxan-3-yl)piperidin-4-amine;2-[[1-[6-methyl-3-(3-methyl-1,2,4-oxadiazol-5-yl)quinolin-2-yl]piperidin-4-yl]amino]cyclohexan-1-ol;4-[[1-[6-methyl-3-(3-methyl-1,2,4-oxadiazol-5-yl)quinolin-2-yl]piperidin-4-yl]amino]cyclohexan-1-ol

(3R,4R)-4-(cyclohexylamino)-1-(5-methyl-3-pyrimidin-2-yl-2-pyridinyl)piperidin-3-ol;[4-(cyclohexylamino)-1-(5-methyl-3-pyrimidin-2-yl-2-pyridinyl)piperidin-3-yl]methanol;N-(2-fluorocyclohexyl)-3-methoxy-1-[6-methyl-3-(3-methyl-1,2,4-oxadiazol-5-yl)quinolin-2-yl]piperidin-4-amine;1-[6-methyl-3-(3-methyl-1,2,4-oxadiazol-5-yl)quinolin-2-yl]-N-(oxan-3-yl)piperidin-4-amine;2-[[1-[6-methyl-3-(3-methyl-1,2,4-oxadiazol-5-yl)quinolin-2-yl]piperidin-4-yl]amino]cyclohexan-1-ol;4-[[1-[6-methyl-3-(3-methyl-1,2,4-oxadiazol-5-yl)quinolin-2-yl]piperidin-4-yl]amino]cyclohexan-1-ol (PubChem CID 157180679) has the molecular formula C139H183FN30O10 and a molecular weight of 2453.19 g/mol. Its IUPAC name is (3R,4R)-4-(cyclohexylamino)-1-(5-methyl-3-pyrimidin-2-yl-2-pyridinyl)piperidin-3-ol;[4-(cyclohexylamino)-1-(5-methyl-3-pyrimidin-2-yl-2-pyridinyl)piperidin-3-yl]methanol;N-(2-fluorocyclohexyl)-3-methoxy-1-[6-methyl-3-(3-methyl-1,2,4-oxadiazol-5-yl)quinolin-2-yl]piperidin-4-amine;1-[6-methyl-3-(3-methyl-1,2,4-oxadiazol-5-yl)quinolin-2-yl]-N-(oxan-3-yl)piperidin-4-amine;2-[[1-[6-methyl-3-(3-methyl-1,2,4-oxadiazol-5-yl)quinolin-2-yl]piperidin-4-yl]amino]cyclohexan-1-ol;4-[[1-[6-methyl-3-(3-methyl-1,2,4-oxadiazol-5-yl)quinolin-2-yl]piperidin-4-yl]amino]cyclohexan-1-ol.

Molecular Properties

• Compound Name: (3R,4R)-4-(cyclohexylamino)-1-(5-methyl-3-pyrimidin-2-yl-2-pyridinyl)piperidin-3-ol;[4-(cyclohexylamino)-1-(5-methyl-3-pyrimidin-2-yl-2-pyridinyl)piperidin-3-yl]methanol;N-(2-fluorocyclohexyl)-3-methoxy-1-[6-methyl-3-(3-methyl-1,2,4-oxadiazol-5-yl)quinolin-2-yl]piperidin-4-amine;1-[6-methyl-3-(3-methyl-1,2,4-oxadiazol-5-yl)quinolin-2-yl]-N-(oxan-3-yl)piperidin-4-amine;2-[[1-[6-methyl-3-(3-methyl-1,2,4-oxadiazol-5-yl)quinolin-2-yl]piperidin-4-yl]amino]cyclohexan-1-ol;4-[[1-[6-methyl-3-(3-methyl-1,2,4-oxadiazol-5-yl)quinolin-2-yl]piperidin-4-yl]amino]cyclohexan-1-ol
• PubChem CID: 157180679
• Molecular Formula: C139H183FN30O10
• Molecular Weight: 2453.19 g/mol
• Exact Mass: 2451.47
• IUPAC Name: (3R,4R)-4-(cyclohexylamino)-1-(5-methyl-3-pyrimidin-2-yl-2-pyridinyl)piperidin-3-ol;[4-(cyclohexylamino)-1-(5-methyl-3-pyrimidin-2-yl-2-pyridinyl)piperidin-3-yl]methanol;N-(2-fluorocyclohexyl)-3-methoxy-1-[6-methyl-3-(3-methyl-1,2,4-oxadiazol-5-yl)quinolin-2-yl]piperidin-4-amine;1-[6-methyl-3-(3-methyl-1,2,4-oxadiazol-5-yl)quinolin-2-yl]-N-(oxan-3-yl)piperidin-4-amine;2-[[1-[6-methyl-3-(3-methyl-1,2,4-oxadiazol-5-yl)quinolin-2-yl]piperidin-4-yl]amino]cyclohexan-1-ol;4-[[1-[6-methyl-3-(3-methyl-1,2,4-oxadiazol-5-yl)quinolin-2-yl]piperidin-4-yl]amino]cyclohexan-1-ol
• SMILES: COC1CN(c2nc3ccc(C)cc3cc2-c2nc(C)no2)CCC1NC1CCCCC1F.Cc1ccc2nc(N3CCC(NC4CCC(O)CC4)CC3)c(-c3nc(C)no3)cc2c1.Cc1ccc2nc(N3CCC(NC4CCCCC4O)CC3)c(-c3nc(C)no3)cc2c1.Cc1ccc2nc(N3CCC(NC4CCCOC4)CC3)c(-c3nc(C)no3)cc2c1.Cc1cnc(N2CCC(NC3CCCCC3)C(CO)C2)c(-c2ncccn2)c1.Cc1cnc(N2CC[C@@H](NC3CCCCC3)[C@H](O)C2)c(-c2ncccn2)c1
• InChI: InChI=1S/C25H32FN5O2.2C24H31N5O2.C23H29N5O2.C22H31N5O.C21H29N5O/c1-15-8-9-20-17(12-15)13-18(25-27-16(2)30-33-25)24(29-20)31-11-10-22(23(14-31)32-3)28-21-7-5-4-6-19(21)26;1-15-3-8-22-17(13-15)14-21(24-25-16(2)28-31-24)23(27-22)29-11-9-19(10-12-29)26-18-4-6-20(30)7-5-18;1-15-7-8-20-17(13-15)14-19(24-25-16(2)28-31-24)23(27-20)29-11-9-18(10-12-29)26-21-5-3-4-6-22(21)30;1-15-5-6-21-17(12-15)13-20(23-24-16(2)27-30-23)22(26-21)28-9-7-18(8-10-28)25-19-4-3-11-29-14-19;1-16-12-19(21-23-9-5-10-24-21)22(25-13-16)27-11-8-20(17(14-27)15-28)26-18-6-3-2-4-7-18;1-15-12-17(20-22-9-5-10-23-20)21(24-13-15)26-11-8-18(19(27)14-26)25-16-6-3-2-4-7-16/h8-9,12-13,19,21-23,28H,4-7,10-11,14H2,1-3H3;3,8,13-14,18-20,26,30H,4-7,9-12H2,1-2H3;7-8,13-14,18,21-22,26,30H,3-6,9-12H2,1-2H3;5-6,12-13,18-19,25H,3-4,7-11,14H2,1-2H3;5,9-10,12-13,17-18,20,26,28H,2-4,6-8,11,14-15H2,1H3;5,9-10,12-13,16,18-19,25,27H,2-4,6-8,11,14H2,1H3/t;;;;;18-,19-/m.....1/s1
• InChIKey: AONNRJAXCLIXLL-WAOQJNEYSA-N
• XLogP: 21.20
• TPSA: 475.58 Ų
• H-Bond Donors: 10
• H-Bond Acceptors: 40
• Rotatable Bonds: 26
• Heavy Atoms: 180
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2453.19
LogP ≤ 5	21.20
H-Bond Donors ≤ 5	10
H-Bond Acceptors ≤ 10	40

Frequently Asked Questions

What is the IUPAC name of (3R,4R)-4-(cyclohexylamino)-1-(5-methyl-3-pyrimidin-2-yl-2-pyridinyl)piperidin-3-ol;[4-(cyclohexylamino)-1-(5-methyl-3-pyrimidin-2-yl-2-pyridinyl)piperidin-3-yl]methanol;N-(2-fluorocyclohexyl)-3-methoxy-1-[6-methyl-3-(3-methyl-1,2,4-oxadiazol-5-yl)quinolin-2-yl]piperidin-4-amine;1-[6-methyl-3-(3-methyl-1,2,4-oxadiazol-5-yl)quinolin-2-yl]-N-(oxan-3-yl)piperidin-4-amine;2-[[1-[6-methyl-3-(3-methyl-1,2,4-oxadiazol-5-yl)quinolin-2-yl]piperidin-4-yl]amino]cyclohexan-1-ol;4-[[1-[6-methyl-3-(3-methyl-1,2,4-oxadiazol-5-yl)quinolin-2-yl]piperidin-4-yl]amino]cyclohexan-1-ol?

The IUPAC name of (3R,4R)-4-(cyclohexylamino)-1-(5-methyl-3-pyrimidin-2-yl-2-pyridinyl)piperidin-3-ol;[4-(cyclohexylamino)-1-(5-methyl-3-pyrimidin-2-yl-2-pyridinyl)piperidin-3-yl]methanol;N-(2-fluorocyclohexyl)-3-methoxy-1-[6-methyl-3-(3-methyl-1,2,4-oxadiazol-5-yl)quinolin-2-yl]piperidin-4-amine;1-[6-methyl-3-(3-methyl-1,2,4-oxadiazol-5-yl)quinolin-2-yl]-N-(oxan-3-yl)piperidin-4-amine;2-[[1-[6-methyl-3-(3-methyl-1,2,4-oxadiazol-5-yl)quinolin-2-yl]piperidin-4-yl]amino]cyclohexan-1-ol;4-[[1-[6-methyl-3-(3-methyl-1,2,4-oxadiazol-5-yl)quinolin-2-yl]piperidin-4-yl]amino]cyclohexan-1-ol (CID 157180679) is (3R,4R)-4-(cyclohexylamino)-1-(5-methyl-3-pyrimidin-2-yl-2-pyridinyl)piperidin-3-ol;[4-(cyclohexylamino)-1-(5-methyl-3-pyrimidin-2-yl-2-pyridinyl)piperidin-3-yl]methanol;N-(2-fluorocyclohexyl)-3-methoxy-1-[6-methyl-3-(3-methyl-1,2,4-oxadiazol-5-yl)quinolin-2-yl]piperidin-4-amine;1-[6-methyl-3-(3-methyl-1,2,4-oxadiazol-5-yl)quinolin-2-yl]-N-(oxan-3-yl)piperidin-4-amine;2-[[1-[6-methyl-3-(3-methyl-1,2,4-oxadiazol-5-yl)quinolin-2-yl]piperidin-4-yl]amino]cyclohexan-1-ol;4-[[1-[6-methyl-3-(3-methyl-1,2,4-oxadiazol-5-yl)quinolin-2-yl]piperidin-4-yl]amino]cyclohexan-1-ol.

What is the SMILES notation for (3R,4R)-4-(cyclohexylamino)-1-(5-methyl-3-pyrimidin-2-yl-2-pyridinyl)piperidin-3-ol;[4-(cyclohexylamino)-1-(5-methyl-3-pyrimidin-2-yl-2-pyridinyl)piperidin-3-yl]methanol;N-(2-fluorocyclohexyl)-3-methoxy-1-[6-methyl-3-(3-methyl-1,2,4-oxadiazol-5-yl)quinolin-2-yl]piperidin-4-amine;1-[6-methyl-3-(3-methyl-1,2,4-oxadiazol-5-yl)quinolin-2-yl]-N-(oxan-3-yl)piperidin-4-amine;2-[[1-[6-methyl-3-(3-methyl-1,2,4-oxadiazol-5-yl)quinolin-2-yl]piperidin-4-yl]amino]cyclohexan-1-ol;4-[[1-[6-methyl-3-(3-methyl-1,2,4-oxadiazol-5-yl)quinolin-2-yl]piperidin-4-yl]amino]cyclohexan-1-ol?

The canonical SMILES for (3R,4R)-4-(cyclohexylamino)-1-(5-methyl-3-pyrimidin-2-yl-2-pyridinyl)piperidin-3-ol;[4-(cyclohexylamino)-1-(5-methyl-3-pyrimidin-2-yl-2-pyridinyl)piperidin-3-yl]methanol;N-(2-fluorocyclohexyl)-3-methoxy-1-[6-methyl-3-(3-methyl-1,2,4-oxadiazol-5-yl)quinolin-2-yl]piperidin-4-amine;1-[6-methyl-3-(3-methyl-1,2,4-oxadiazol-5-yl)quinolin-2-yl]-N-(oxan-3-yl)piperidin-4-amine;2-[[1-[6-methyl-3-(3-methyl-1,2,4-oxadiazol-5-yl)quinolin-2-yl]piperidin-4-yl]amino]cyclohexan-1-ol;4-[[1-[6-methyl-3-(3-methyl-1,2,4-oxadiazol-5-yl)quinolin-2-yl]piperidin-4-yl]amino]cyclohexan-1-ol is COC1CN(c2nc3ccc(C)cc3cc2-c2nc(C)no2)CCC1NC1CCCCC1F.Cc1ccc2nc(N3CCC(NC4CCC(O)CC4)CC3)c(-c3nc(C)no3)cc2c1.Cc1ccc2nc(N3CCC(NC4CCCCC4O)CC3)c(-c3nc(C)no3)cc2c1.Cc1ccc2nc(N3CCC(NC4CCCOC4)CC3)c(-c3nc(C)no3)cc2c1.Cc1cnc(N2CCC(NC3CCCCC3)C(CO)C2)c(-c2ncccn2)c1.Cc1cnc(N2CC[C@@H](NC3CCCCC3)[C@H](O)C2)c(-c2ncccn2)c1.

What is the InChIKey of (3R,4R)-4-(cyclohexylamino)-1-(5-methyl-3-pyrimidin-2-yl-2-pyridinyl)piperidin-3-ol;[4-(cyclohexylamino)-1-(5-methyl-3-pyrimidin-2-yl-2-pyridinyl)piperidin-3-yl]methanol;N-(2-fluorocyclohexyl)-3-methoxy-1-[6-methyl-3-(3-methyl-1,2,4-oxadiazol-5-yl)quinolin-2-yl]piperidin-4-amine;1-[6-methyl-3-(3-methyl-1,2,4-oxadiazol-5-yl)quinolin-2-yl]-N-(oxan-3-yl)piperidin-4-amine;2-[[1-[6-methyl-3-(3-methyl-1,2,4-oxadiazol-5-yl)quinolin-2-yl]piperidin-4-yl]amino]cyclohexan-1-ol;4-[[1-[6-methyl-3-(3-methyl-1,2,4-oxadiazol-5-yl)quinolin-2-yl]piperidin-4-yl]amino]cyclohexan-1-ol?

The InChIKey is AONNRJAXCLIXLL-WAOQJNEYSA-N. The full InChI is InChI=1S/C25H32FN5O2.2C24H31N5O2.C23H29N5O2.C22H31N5O.C21H29N5O/c1-15-8-9-20-17(12-15)13-18(25-27-16(2)30-33-25)24(29-20)31-11-10-22(23(14-31)32-3)28-21-7-5-4-6-19(21)26;1-15-3-8-22-17(13-15)14-21(24-25-16(2)28-31-24)23(27-22)29-11-9-19(10-12-29)26-18-4-6-20(30)7-5-18;1-15-7-8-20-17(13-15)14-19(24-25-16(2)28-31-24)23(27-20)29-11-9-18(10-12-29)26-21-5-3-4-6-22(21)30;1-15-5-6-21-17(12-15)13-20(23-24-16(2)27-30-23)22(26-21)28-9-7-18(8-10-28)25-19-4-3-11-29-14-19;1-16-12-19(21-23-9-5-10-24-21)22(25-13-16)27-11-8-20(17(14-27)15-28)26-18-6-3-2-4-7-18;1-15-12-17(20-22-9-5-10-23-20)21(24-13-15)26-11-8-18(19(27)14-26)25-16-6-3-2-4-7-16/h8-9,12-13,19,21-23,28H,4-7,10-11,14H2,1-3H3;3,8,13-14,18-20,26,30H,4-7,9-12H2,1-2H3;7-8,13-14,18,21-22,26,30H,3-6,9-12H2,1-2H3;5-6,12-13,18-19,25H,3-4,7-11,14H2,1-2H3;5,9-10,12-13,17-18,20,26,28H,2-4,6-8,11,14-15H2,1H3;5,9-10,12-13,16,18-19,25,27H,2-4,6-8,11,14H2,1H3/t;;;;;18-,19-/m.....1/s1.

What are the key properties of (3R,4R)-4-(cyclohexylamino)-1-(5-methyl-3-pyrimidin-2-yl-2-pyridinyl)piperidin-3-ol;[4-(cyclohexylamino)-1-(5-methyl-3-pyrimidin-2-yl-2-pyridinyl)piperidin-3-yl]methanol;N-(2-fluorocyclohexyl)-3-methoxy-1-[6-methyl-3-(3-methyl-1,2,4-oxadiazol-5-yl)quinolin-2-yl]piperidin-4-amine;1-[6-methyl-3-(3-methyl-1,2,4-oxadiazol-5-yl)quinolin-2-yl]-N-(oxan-3-yl)piperidin-4-amine;2-[[1-[6-methyl-3-(3-methyl-1,2,4-oxadiazol-5-yl)quinolin-2-yl]piperidin-4-yl]amino]cyclohexan-1-ol;4-[[1-[6-methyl-3-(3-methyl-1,2,4-oxadiazol-5-yl)quinolin-2-yl]piperidin-4-yl]amino]cyclohexan-1-ol?

(3R,4R)-4-(cyclohexylamino)-1-(5-methyl-3-pyrimidin-2-yl-2-pyridinyl)piperidin-3-ol;[4-(cyclohexylamino)-1-(5-methyl-3-pyrimidin-2-yl-2-pyridinyl)piperidin-3-yl]methanol;N-(2-fluorocyclohexyl)-3-methoxy-1-[6-methyl-3-(3-methyl-1,2,4-oxadiazol-5-yl)quinolin-2-yl]piperidin-4-amine;1-[6-methyl-3-(3-methyl-1,2,4-oxadiazol-5-yl)quinolin-2-yl]-N-(oxan-3-yl)piperidin-4-amine;2-[[1-[6-methyl-3-(3-methyl-1,2,4-oxadiazol-5-yl)quinolin-2-yl]piperidin-4-yl]amino]cyclohexan-1-ol;4-[[1-[6-methyl-3-(3-methyl-1,2,4-oxadiazol-5-yl)quinolin-2-yl]piperidin-4-yl]amino]cyclohexan-1-ol has a molecular weight of 2453.19 g/mol, XLogP of 21.20, 26 rotatable bonds, 10 hydrogen bond donors, and 40 hydrogen bond acceptors.

Where does this data come from?

All data for (3R,4R)-4-(cyclohexylamino)-1-(5-methyl-3-pyrimidin-2-yl-2-pyridinyl)piperidin-3-ol;[4-(cyclohexylamino)-1-(5-methyl-3-pyrimidin-2-yl-2-pyridinyl)piperidin-3-yl]methanol;N-(2-fluorocyclohexyl)-3-methoxy-1-[6-methyl-3-(3-methyl-1,2,4-oxadiazol-5-yl)quinolin-2-yl]piperidin-4-amine;1-[6-methyl-3-(3-methyl-1,2,4-oxadiazol-5-yl)quinolin-2-yl]-N-(oxan-3-yl)piperidin-4-amine;2-[[1-[6-methyl-3-(3-methyl-1,2,4-oxadiazol-5-yl)quinolin-2-yl]piperidin-4-yl]amino]cyclohexan-1-ol;4-[[1-[6-methyl-3-(3-methyl-1,2,4-oxadiazol-5-yl)quinolin-2-yl]piperidin-4-yl]amino]cyclohexan-1-ol is sourced from PubChem (CID 157180679), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).