[2-amino-5-[[(1S)-1-phenylethyl]amino]-[1,3]thiazolo[4,5-d]pyrimidin-7-yl]-pyrrolidin-1-ylmethanone;1-[5-[[(1S)-1-(5-fluoro-3-pyridinyl)ethyl]amino]-2-methyl-[1,3]thiazolo[4,5-d]pyrimidin-7-yl]-4-(4-methylphenyl)butan-1-one;[(3S)-3-hydroxypyrrolidin-1-yl]-[2-methyl-5-[[(1S)-1-phenylethyl]amino]-[1,3]thiazolo[4,5-d]pyrimidin-7-yl]methanone;[(3R)-3-hydroxypyrrolidin-1-yl]-[2-methyl-5-[[(1S)-1-pyridin-2-ylethyl]amino]-[1,3]thiazolo[4,5-d]pyrimidin-7-yl]methanone

C79H85FN22O6S4 — CID 157198060

IUPAC[2-amino-5-[[(1S)-1-phenylethyl]amino]-[1,3]thiazolo[4,5-d]pyrimidin-7-yl]-pyrrolidin-1-ylmethanone;1-[5-[[(1S)-1-(5-fluoro-3-pyridinyl)ethyl]amino]-2-methyl-[1,3]thiazolo[4,5-d]pyrimidin-7-yl]-4-(4-methylphenyl)butan-1-one;[(3S)-3-hydroxypyrrolidin-1-yl]-[2-methyl-5-[[(1S)-1-phenylethyl]amino]-[1,3]thiazolo[4,5-d]pyrimidin-7-yl]methanone;[(3R)-3-hydroxypyrrolidin-1-yl]-[2-methyl-5-[[(1S)-1-pyridin-2-ylethyl]amino]-[1,3]thiazolo[4,5-d]pyrimidin-7-yl]methanone
SMILESC[C@H](Nc1nc(C(=O)N2CCCC2)c2sc(N)nc2n1)c1ccccc1.Cc1ccc(CCCC(=O)c2nc(N[C@@H](C)c3cncc(F)c3)nc3nc(C)sc23)cc1.Cc1nc2nc(N[C@@H](C)c3ccccc3)nc(C(=O)N3CC[C@H](O)C3)c2s1.Cc1nc2nc(N[C@@H](C)c3ccccn3)nc(C(=O)N3CC[C@@H](O)C3)c2s1
InChIInChI=1S/C24H24FN5OS.C19H21N5O2S.C18H20N6O2S.C18H20N6OS/c1-14-7-9-17(10-8-14)5-4-6-20(31)21-22-23(28-16(3)32-22)30-24(29-21)27-15(2)18-11-19(25)13-26-12-18;1-11(13-6-4-3-5-7-13)20-19-22-15(16-17(23-19)21-12(2)27-16)18(26)24-9-8-14(25)10-24;1-10(13-5-3-4-7-19-13)20-18-22-14(15-16(23-18)21-11(2)27-15)17(26)24-8-6-12(25)9-24;1-11(12-7-3-2-4-8-12)20-18-21-13(16(25)24-9-5-6-10-24)14-15(23-18)22-17(19)26-14/h7-13,15H,4-6H2,1-3H3,(H,27,29,30);3-7,11,14,25H,8-10H2,1-2H3,(H,20,22,23);3-5,7,10,12,25H,6,8-9H2,1-2H3,(H,20,22,23);2-4,7-8,11H,5-6,9-10H2,1H3,(H3,19,20,21,22,23)/t15-;11-,14-;10-,12+;11-/m0000/s1
InChIKeyAQMAOSXBAFGJCE-NWEBBWMDSA-N
MW1585.96 g/mol
LogP13.64
Rot. Bonds20

About [2-amino-5-[[(1S)-1-phenylethyl]amino]-[1,3]thiazolo[4,5-d]pyrimidin-7-yl]-pyrrolidin-1-ylmethanone;1-[5-[[(1S)-1-(5-fluoro-3-pyridinyl)ethyl]amino]-2-methyl-[1,3]thiazolo[4,5-d]pyrimidin-7-yl]-4-(4-methylphenyl)butan-1-one;[(3S)-3-hydroxypyrrolidin-1-yl]-[2-methyl-5-[[(1S)-1-phenylethyl]amino]-[1,3]thiazolo[4,5-d]pyrimidin-7-yl]methanone;[(3R)-3-hydroxypyrrolidin-1-yl]-[2-methyl-5-[[(1S)-1-pyridin-2-ylethyl]amino]-[1,3]thiazolo[4,5-d]pyrimidin-7-yl]methanone

[2-amino-5-[[(1S)-1-phenylethyl]amino]-[1,3]thiazolo[4,5-d]pyrimidin-7-yl]-pyrrolidin-1-ylmethanone;1-[5-[[(1S)-1-(5-fluoro-3-pyridinyl)ethyl]amino]-2-methyl-[1,3]thiazolo[4,5-d]pyrimidin-7-yl]-4-(4-methylphenyl)butan-1-one;[(3S)-3-hydroxypyrrolidin-1-yl]-[2-methyl-5-[[(1S)-1-phenylethyl]amino]-[1,3]thiazolo[4,5-d]pyrimidin-7-yl]methanone;[(3R)-3-hydroxypyrrolidin-1-yl]-[2-methyl-5-[[(1S)-1-pyridin-2-ylethyl]amino]-[1,3]thiazolo[4,5-d]pyrimidin-7-yl]methanone (PubChem CID 157198060) has the molecular formula C79H85FN22O6S4 and a molecular weight of 1585.96 g/mol. Its IUPAC name is [2-amino-5-[[(1S)-1-phenylethyl]amino]-[1,3]thiazolo[4,5-d]pyrimidin-7-yl]-pyrrolidin-1-ylmethanone;1-[5-[[(1S)-1-(5-fluoro-3-pyridinyl)ethyl]amino]-2-methyl-[1,3]thiazolo[4,5-d]pyrimidin-7-yl]-4-(4-methylphenyl)butan-1-one;[(3S)-3-hydroxypyrrolidin-1-yl]-[2-methyl-5-[[(1S)-1-phenylethyl]amino]-[1,3]thiazolo[4,5-d]pyrimidin-7-yl]methanone;[(3R)-3-hydroxypyrrolidin-1-yl]-[2-methyl-5-[[(1S)-1-pyridin-2-ylethyl]amino]-[1,3]thiazolo[4,5-d]pyrimidin-7-yl]methanone.

Molecular Properties

Compound Name[2-amino-5-[[(1S)-1-phenylethyl]amino]-[1,3]thiazolo[4,5-d]pyrimidin-7-yl]-pyrrolidin-1-ylmethanone;1-[5-[[(1S)-1-(5-fluoro-3-pyridinyl)ethyl]amino]-2-methyl-[1,3]thiazolo[4,5-d]pyrimidin-7-yl]-4-(4-methylphenyl)butan-1-one;[(3S)-3-hydroxypyrrolidin-1-yl]-[2-methyl-5-[[(1S)-1-phenylethyl]amino]-[1,3]thiazolo[4,5-d]pyrimidin-7-yl]methanone;[(3R)-3-hydroxypyrrolidin-1-yl]-[2-methyl-5-[[(1S)-1-pyridin-2-ylethyl]amino]-[1,3]thiazolo[4,5-d]pyrimidin-7-yl]methanone
PubChem CID157198060
Molecular FormulaC79H85FN22O6S4
Molecular Weight1585.96 g/mol
Exact Mass1584.59
IUPAC Name[2-amino-5-[[(1S)-1-phenylethyl]amino]-[1,3]thiazolo[4,5-d]pyrimidin-7-yl]-pyrrolidin-1-ylmethanone;1-[5-[[(1S)-1-(5-fluoro-3-pyridinyl)ethyl]amino]-2-methyl-[1,3]thiazolo[4,5-d]pyrimidin-7-yl]-4-(4-methylphenyl)butan-1-one;[(3S)-3-hydroxypyrrolidin-1-yl]-[2-methyl-5-[[(1S)-1-phenylethyl]amino]-[1,3]thiazolo[4,5-d]pyrimidin-7-yl]methanone;[(3R)-3-hydroxypyrrolidin-1-yl]-[2-methyl-5-[[(1S)-1-pyridin-2-ylethyl]amino]-[1,3]thiazolo[4,5-d]pyrimidin-7-yl]methanone
SMILESC[C@H](Nc1nc(C(=O)N2CCCC2)c2sc(N)nc2n1)c1ccccc1.Cc1ccc(CCCC(=O)c2nc(N[C@@H](C)c3cncc(F)c3)nc3nc(C)sc23)cc1.Cc1nc2nc(N[C@@H](C)c3ccccc3)nc(C(=O)N3CC[C@H](O)C3)c2s1.Cc1nc2nc(N[C@@H](C)c3ccccn3)nc(C(=O)N3CC[C@@H](O)C3)c2s1
InChIInChI=1S/C24H24FN5OS.C19H21N5O2S.C18H20N6O2S.C18H20N6OS/c1-14-7-9-17(10-8-14)5-4-6-20(31)21-22-23(28-16(3)32-22)30-24(29-21)27-15(2)18-11-19(25)13-26-12-18;1-11(13-6-4-3-5-7-13)20-19-22-15(16-17(23-19)21-12(2)27-16)18(26)24-9-8-14(25)10-24;1-10(13-5-3-4-7-19-13)20-18-22-14(15-16(23-18)21-11(2)27-15)17(26)24-8-6-12(25)9-24;1-11(12-7-3-2-4-8-12)20-18-21-13(16(25)24-9-5-6-10-24)14-15(23-18)22-17(19)26-14/h7-13,15H,4-6H2,1-3H3,(H,27,29,30);3-7,11,14,25H,8-10H2,1-2H3,(H,20,22,23);3-5,7,10,12,25H,6,8-9H2,1-2H3,(H,20,22,23);2-4,7-8,11H,5-6,9-10H2,1H3,(H3,19,20,21,22,23)/t15-;11-,14-;10-,12+;11-/m0000/s1
InChIKeyAQMAOSXBAFGJCE-NWEBBWMDSA-N
XLogP13.64
TPSA373.06 Ų
H-Bond Donors7
H-Bond Acceptors29
Rotatable Bonds20
Heavy Atoms112
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5001585.96
LogP ≤ 513.64
H-Bond Donors ≤ 57
H-Bond Acceptors ≤ 1029

Analyze [2-amino-5-[[(1S)-1-phenylethyl]amino]-[1,3]thiazolo[4,5-d]pyrimidin-7-yl]-pyrrolidin-1-ylmethanone;1-[5-[[(1S)-1-(5-fluoro-3-pyridinyl)ethyl]amino]-2-methyl-[1,3]thiazolo[4,5-d]pyrimidin-7-yl]-4-(4-methylphenyl)butan-1-one;[(3S)-3-hydroxypyrrolidin-1-yl]-[2-methyl-5-[[(1S)-1-phenylethyl]amino]-[1,3]thiazolo[4,5-d]pyrimidin-7-yl]methanone;[(3R)-3-hydroxypyrrolidin-1-yl]-[2-methyl-5-[[(1S)-1-pyridin-2-ylethyl]amino]-[1,3]thiazolo[4,5-d]pyrimidin-7-yl]methanone with MolForge

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Related Compounds

(2S,4R)-1-[(2S)-2-[[2-[4-[[1-[4-[3-[2,6-difluoro-3-[[(3R)-3-fluoropyrrolidin-1-yl]sulfonylamino]benzoyl]-1H-pyrrolo[2,3-b]pyridin-5-yl]phenyl]piperidin-4-yl]methyl]piperazin-1-yl]acetyl]amino]-3,3-dimethylbutanoyl]-4-hydroxy-N-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]pyrrolidine-2-carboxamide
CID 135147114
(2S,4R)-1-[(2S)-2-[[2-[4-[[4-[4-[3-[2,6-difluoro-3-[[(3R)-3-fluoropyrrolidin-1-yl]sulfonylamino]benzoyl]-1H-pyrrolo[2,3-b]pyridin-5-yl]phenyl]piperazin-1-yl]methyl]piperidin-1-yl]acetyl]amino]-3,3-dimethylbutanoyl]-4-hydroxy-N-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]pyrrolidine-2-carboxamide
CID 135147196
(2S,4R)-1-[(2S)-2-[[2-[4-[[4-[4-[3-[2,6-difluoro-3-[[(3R)-3-fluoropyrrolidin-1-yl]sulfonylamino]benzoyl]-1H-pyrrolo[2,3-b]pyridin-5-yl]phenyl]piperazin-1-yl]methyl]piperidin-1-yl]acetyl]amino]-3,3-dimethylbutanoyl]-4-hydroxy-N-[(1S)-1-[4-(4-methyl-1,3-thiazol-5-yl)phenyl]ethyl]pyrrolidine-2-carboxamide
CID 155013383
(2S,4R)-1-[(2S)-2-[[2-[4-[5-[3-[3-[[ethyl(methyl)sulfamoyl]amino]-2,6-difluorobenzoyl]-1H-pyrrolo[2,3-b]pyridin-5-yl]pyrimidin-2-yl]piperazin-1-yl]acetyl]amino]-3,3-dimethylbutanoyl]-4-hydroxy-N-[(1S)-1-[4-(4-methyl-1,3-thiazol-5-yl)phenyl]ethyl]pyrrolidine-2-carboxamide
CID 168277926
(2S,4R)-1-[2-[[2-[4-[[1-[4-[3-[2,6-difluoro-3-[[(3R)-3-fluoropyrrolidin-1-yl]sulfonylamino]benzoyl]-1H-pyrrolo[2,3-b]pyridin-5-yl]phenyl]piperidin-4-yl]methyl]piperazin-1-yl]acetyl]amino]-3,3-dimethylbutanoyl]-4-hydroxy-N-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]pyrrolidine-2-carboxamide
CID 135147116
(2S,4R)-1-[2-[[2-[4-[[1-[4-[3-[2,6-difluoro-3-[(3-fluoropyrrolidin-1-yl)sulfonylamino]benzoyl]-1H-pyrrolo[2,3-b]pyridin-5-yl]phenyl]piperidin-4-yl]methyl]piperazin-1-yl]acetyl]amino]-3,3-dimethylbutanoyl]-4-hydroxy-N-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]pyrrolidine-2-carboxamide
CID 135147117
(2S,4R)-1-[2-[[2-[4-[[4-[4-[3-[2,6-difluoro-3-[[(3R)-3-fluoropyrrolidin-1-yl]sulfonylamino]benzoyl]-1H-pyrrolo[2,3-b]pyridin-5-yl]phenyl]piperazin-1-yl]methyl]piperidin-1-yl]acetyl]amino]-3,3-dimethylbutanoyl]-4-hydroxy-N-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]pyrrolidine-2-carboxamide
CID 135147198
(2S,4R)-1-[2-[[2-[4-[[4-[4-[3-[2,6-difluoro-3-[(3-fluoropyrrolidin-1-yl)sulfonylamino]benzoyl]-1H-pyrrolo[2,3-b]pyridin-5-yl]phenyl]piperazin-1-yl]methyl]piperidin-1-yl]acetyl]amino]-3,3-dimethylbutanoyl]-4-hydroxy-N-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]pyrrolidine-2-carboxamide
CID 135147200
5-[1-(5-fluoro-3-pyridinyl)ethylamino]-N-[2-[4-[3-[5-[1-(5-fluoro-3-pyridinyl)ethylamino]-7-(2-methoxyethylcarbamoyl)-[1,3]thiazolo[4,5-d]pyrimidin-2-yl]propanoylamino]phenyl]ethyl]-2-methyl-[1,3]thiazolo[4,5-d]pyrimidine-7-carboxamide
CID 146427423
(2S,4R)-1-[(2S)-2-[[2-[4-[[4-[4-[3-[2-fluoro-3-[[(3R)-3-fluoropyrrolidin-1-yl]sulfonylamino]benzoyl]-1H-pyrrolo[2,3-b]pyridin-5-yl]phenyl]piperazin-1-yl]methyl]piperidin-1-yl]acetyl]amino]-3,3-dimethylbutanoyl]-4-hydroxy-N-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]pyrrolidine-2-carboxamide
CID 146501937
(2S,4R)-1-[2-[[2-[4-[[4-[4-[3-[2-fluoro-3-[[(3R)-3-fluoropyrrolidin-1-yl]sulfonylamino]benzoyl]-1H-pyrrolo[2,3-b]pyridin-5-yl]phenyl]piperazin-1-yl]methyl]piperidin-1-yl]acetyl]amino]-3,3-dimethylbutanoyl]-4-hydroxy-N-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]pyrrolidine-2-carboxamide
CID 146501941
(2S,4R)-1-[(2S)-2-[[2-[4-[[4-[4-[3-[2,6-difluoro-3-[[(3R)-3-fluoropyrrolidin-1-yl]sulfonyl-methylamino]benzoyl]-1H-pyrrolo[2,3-b]pyridin-5-yl]phenyl]piperazin-1-yl]methyl]piperidin-1-yl]acetyl]amino]-3,3-dimethylbutanoyl]-4-hydroxy-N-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]pyrrolidine-2-carboxamide
CID 146502095

Frequently Asked Questions

What is the IUPAC name of [2-amino-5-[[(1S)-1-phenylethyl]amino]-[1,3]thiazolo[4,5-d]pyrimidin-7-yl]-pyrrolidin-1-ylmethanone;1-[5-[[(1S)-1-(5-fluoro-3-pyridinyl)ethyl]amino]-2-methyl-[1,3]thiazolo[4,5-d]pyrimidin-7-yl]-4-(4-methylphenyl)butan-1-one;[(3S)-3-hydroxypyrrolidin-1-yl]-[2-methyl-5-[[(1S)-1-phenylethyl]amino]-[1,3]thiazolo[4,5-d]pyrimidin-7-yl]methanone;[(3R)-3-hydroxypyrrolidin-1-yl]-[2-methyl-5-[[(1S)-1-pyridin-2-ylethyl]amino]-[1,3]thiazolo[4,5-d]pyrimidin-7-yl]methanone?
The IUPAC name of [2-amino-5-[[(1S)-1-phenylethyl]amino]-[1,3]thiazolo[4,5-d]pyrimidin-7-yl]-pyrrolidin-1-ylmethanone;1-[5-[[(1S)-1-(5-fluoro-3-pyridinyl)ethyl]amino]-2-methyl-[1,3]thiazolo[4,5-d]pyrimidin-7-yl]-4-(4-methylphenyl)butan-1-one;[(3S)-3-hydroxypyrrolidin-1-yl]-[2-methyl-5-[[(1S)-1-phenylethyl]amino]-[1,3]thiazolo[4,5-d]pyrimidin-7-yl]methanone;[(3R)-3-hydroxypyrrolidin-1-yl]-[2-methyl-5-[[(1S)-1-pyridin-2-ylethyl]amino]-[1,3]thiazolo[4,5-d]pyrimidin-7-yl]methanone (CID 157198060) is [2-amino-5-[[(1S)-1-phenylethyl]amino]-[1,3]thiazolo[4,5-d]pyrimidin-7-yl]-pyrrolidin-1-ylmethanone;1-[5-[[(1S)-1-(5-fluoro-3-pyridinyl)ethyl]amino]-2-methyl-[1,3]thiazolo[4,5-d]pyrimidin-7-yl]-4-(4-methylphenyl)butan-1-one;[(3S)-3-hydroxypyrrolidin-1-yl]-[2-methyl-5-[[(1S)-1-phenylethyl]amino]-[1,3]thiazolo[4,5-d]pyrimidin-7-yl]methanone;[(3R)-3-hydroxypyrrolidin-1-yl]-[2-methyl-5-[[(1S)-1-pyridin-2-ylethyl]amino]-[1,3]thiazolo[4,5-d]pyrimidin-7-yl]methanone.
What is the SMILES notation for [2-amino-5-[[(1S)-1-phenylethyl]amino]-[1,3]thiazolo[4,5-d]pyrimidin-7-yl]-pyrrolidin-1-ylmethanone;1-[5-[[(1S)-1-(5-fluoro-3-pyridinyl)ethyl]amino]-2-methyl-[1,3]thiazolo[4,5-d]pyrimidin-7-yl]-4-(4-methylphenyl)butan-1-one;[(3S)-3-hydroxypyrrolidin-1-yl]-[2-methyl-5-[[(1S)-1-phenylethyl]amino]-[1,3]thiazolo[4,5-d]pyrimidin-7-yl]methanone;[(3R)-3-hydroxypyrrolidin-1-yl]-[2-methyl-5-[[(1S)-1-pyridin-2-ylethyl]amino]-[1,3]thiazolo[4,5-d]pyrimidin-7-yl]methanone?
The canonical SMILES for [2-amino-5-[[(1S)-1-phenylethyl]amino]-[1,3]thiazolo[4,5-d]pyrimidin-7-yl]-pyrrolidin-1-ylmethanone;1-[5-[[(1S)-1-(5-fluoro-3-pyridinyl)ethyl]amino]-2-methyl-[1,3]thiazolo[4,5-d]pyrimidin-7-yl]-4-(4-methylphenyl)butan-1-one;[(3S)-3-hydroxypyrrolidin-1-yl]-[2-methyl-5-[[(1S)-1-phenylethyl]amino]-[1,3]thiazolo[4,5-d]pyrimidin-7-yl]methanone;[(3R)-3-hydroxypyrrolidin-1-yl]-[2-methyl-5-[[(1S)-1-pyridin-2-ylethyl]amino]-[1,3]thiazolo[4,5-d]pyrimidin-7-yl]methanone is C[C@H](Nc1nc(C(=O)N2CCCC2)c2sc(N)nc2n1)c1ccccc1.Cc1ccc(CCCC(=O)c2nc(N[C@@H](C)c3cncc(F)c3)nc3nc(C)sc23)cc1.Cc1nc2nc(N[C@@H](C)c3ccccc3)nc(C(=O)N3CC[C@H](O)C3)c2s1.Cc1nc2nc(N[C@@H](C)c3ccccn3)nc(C(=O)N3CC[C@@H](O)C3)c2s1.
What is the InChIKey of [2-amino-5-[[(1S)-1-phenylethyl]amino]-[1,3]thiazolo[4,5-d]pyrimidin-7-yl]-pyrrolidin-1-ylmethanone;1-[5-[[(1S)-1-(5-fluoro-3-pyridinyl)ethyl]amino]-2-methyl-[1,3]thiazolo[4,5-d]pyrimidin-7-yl]-4-(4-methylphenyl)butan-1-one;[(3S)-3-hydroxypyrrolidin-1-yl]-[2-methyl-5-[[(1S)-1-phenylethyl]amino]-[1,3]thiazolo[4,5-d]pyrimidin-7-yl]methanone;[(3R)-3-hydroxypyrrolidin-1-yl]-[2-methyl-5-[[(1S)-1-pyridin-2-ylethyl]amino]-[1,3]thiazolo[4,5-d]pyrimidin-7-yl]methanone?
The InChIKey is AQMAOSXBAFGJCE-NWEBBWMDSA-N. The full InChI is InChI=1S/C24H24FN5OS.C19H21N5O2S.C18H20N6O2S.C18H20N6OS/c1-14-7-9-17(10-8-14)5-4-6-20(31)21-22-23(28-16(3)32-22)30-24(29-21)27-15(2)18-11-19(25)13-26-12-18;1-11(13-6-4-3-5-7-13)20-19-22-15(16-17(23-19)21-12(2)27-16)18(26)24-9-8-14(25)10-24;1-10(13-5-3-4-7-19-13)20-18-22-14(15-16(23-18)21-11(2)27-15)17(26)24-8-6-12(25)9-24;1-11(12-7-3-2-4-8-12)20-18-21-13(16(25)24-9-5-6-10-24)14-15(23-18)22-17(19)26-14/h7-13,15H,4-6H2,1-3H3,(H,27,29,30);3-7,11,14,25H,8-10H2,1-2H3,(H,20,22,23);3-5,7,10,12,25H,6,8-9H2,1-2H3,(H,20,22,23);2-4,7-8,11H,5-6,9-10H2,1H3,(H3,19,20,21,22,23)/t15-;11-,14-;10-,12+;11-/m0000/s1.
What are the key properties of [2-amino-5-[[(1S)-1-phenylethyl]amino]-[1,3]thiazolo[4,5-d]pyrimidin-7-yl]-pyrrolidin-1-ylmethanone;1-[5-[[(1S)-1-(5-fluoro-3-pyridinyl)ethyl]amino]-2-methyl-[1,3]thiazolo[4,5-d]pyrimidin-7-yl]-4-(4-methylphenyl)butan-1-one;[(3S)-3-hydroxypyrrolidin-1-yl]-[2-methyl-5-[[(1S)-1-phenylethyl]amino]-[1,3]thiazolo[4,5-d]pyrimidin-7-yl]methanone;[(3R)-3-hydroxypyrrolidin-1-yl]-[2-methyl-5-[[(1S)-1-pyridin-2-ylethyl]amino]-[1,3]thiazolo[4,5-d]pyrimidin-7-yl]methanone?
[2-amino-5-[[(1S)-1-phenylethyl]amino]-[1,3]thiazolo[4,5-d]pyrimidin-7-yl]-pyrrolidin-1-ylmethanone;1-[5-[[(1S)-1-(5-fluoro-3-pyridinyl)ethyl]amino]-2-methyl-[1,3]thiazolo[4,5-d]pyrimidin-7-yl]-4-(4-methylphenyl)butan-1-one;[(3S)-3-hydroxypyrrolidin-1-yl]-[2-methyl-5-[[(1S)-1-phenylethyl]amino]-[1,3]thiazolo[4,5-d]pyrimidin-7-yl]methanone;[(3R)-3-hydroxypyrrolidin-1-yl]-[2-methyl-5-[[(1S)-1-pyridin-2-ylethyl]amino]-[1,3]thiazolo[4,5-d]pyrimidin-7-yl]methanone has a molecular weight of 1585.96 g/mol, XLogP of 13.64, 20 rotatable bonds, 7 hydrogen bond donors, and 29 hydrogen bond acceptors.
Where does this data come from?
All data for [2-amino-5-[[(1S)-1-phenylethyl]amino]-[1,3]thiazolo[4,5-d]pyrimidin-7-yl]-pyrrolidin-1-ylmethanone;1-[5-[[(1S)-1-(5-fluoro-3-pyridinyl)ethyl]amino]-2-methyl-[1,3]thiazolo[4,5-d]pyrimidin-7-yl]-4-(4-methylphenyl)butan-1-one;[(3S)-3-hydroxypyrrolidin-1-yl]-[2-methyl-5-[[(1S)-1-phenylethyl]amino]-[1,3]thiazolo[4,5-d]pyrimidin-7-yl]methanone;[(3R)-3-hydroxypyrrolidin-1-yl]-[2-methyl-5-[[(1S)-1-pyridin-2-ylethyl]amino]-[1,3]thiazolo[4,5-d]pyrimidin-7-yl]methanone is sourced from PubChem (CID 157198060), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).