(2R)-4-[6-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrazin-2-yl]-2-(2-methylsulfonylethyl)morpholine;(2R,6S)-2-methyl-6-(3-methyl-2H-pyrrol-4-yl)-4-[4-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-2-yl]morpholine;(2S,6R)-2-methyl-6-(3-methyl-2H-pyrrol-4-yl)-4-[4-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-2-yl]morpholine;3-[2-[(3S,5S)-3-methyl-5-(1H-pyrazol-4-yl)piperidin-1-yl]pyrimidin-4-yl]-6-(trifluoromethyl)imidazo[1,2-a]pyridine;N-[[1-[3-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]-1,2,4-thiadiazol-5-yl]piperidin-3-yl]methyl]methanesulfonamide

C100H101ClF12N30O7S3 — CID 157207572

About (2R)-4-[6-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrazin-2-yl]-2-(2-methylsulfonylethyl)morpholine;(2R,6S)-2-methyl-6-(3-methyl-2H-pyrrol-4-yl)-4-[4-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-2-yl]morpholine;(2S,6R)-2-methyl-6-(3-methyl-2H-pyrrol-4-yl)-4-[4-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-2-yl]morpholine;3-[2-[(3S,5S)-3-methyl-5-(1H-pyrazol-4-yl)piperidin-1-yl]pyrimidin-4-yl]-6-(trifluoromethyl)imidazo[1,2-a]pyridine;N-[[1-[3-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]-1,2,4-thiadiazol-5-yl]piperidin-3-yl]methyl]methanesulfonamide

(2R)-4-[6-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrazin-2-yl]-2-(2-methylsulfonylethyl)morpholine;(2R,6S)-2-methyl-6-(3-methyl-2H-pyrrol-4-yl)-4-[4-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-2-yl]morpholine;(2S,6R)-2-methyl-6-(3-methyl-2H-pyrrol-4-yl)-4-[4-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-2-yl]morpholine;3-[2-[(3S,5S)-3-methyl-5-(1H-pyrazol-4-yl)piperidin-1-yl]pyrimidin-4-yl]-6-(trifluoromethyl)imidazo[1,2-a]pyridine;N-[[1-[3-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]-1,2,4-thiadiazol-5-yl]piperidin-3-yl]methyl]methanesulfonamide (PubChem CID 157207572) has the molecular formula C100H101ClF12N30O7S3 and a molecular weight of 2194.74 g/mol. Its IUPAC name is (2R)-4-[6-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrazin-2-yl]-2-(2-methylsulfonylethyl)morpholine;(2R,6S)-2-methyl-6-(3-methyl-2H-pyrrol-4-yl)-4-[4-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-2-yl]morpholine;(2S,6R)-2-methyl-6-(3-methyl-2H-pyrrol-4-yl)-4-[4-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-2-yl]morpholine;3-[2-[(3S,5S)-3-methyl-5-(1H-pyrazol-4-yl)piperidin-1-yl]pyrimidin-4-yl]-6-(trifluoromethyl)imidazo[1,2-a]pyridine;N-[[1-[3-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]-1,2,4-thiadiazol-5-yl]piperidin-3-yl]methyl]methanesulfonamide.

Molecular Properties

• Compound Name: (2R)-4-[6-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrazin-2-yl]-2-(2-methylsulfonylethyl)morpholine;(2R,6S)-2-methyl-6-(3-methyl-2H-pyrrol-4-yl)-4-[4-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-2-yl]morpholine;(2S,6R)-2-methyl-6-(3-methyl-2H-pyrrol-4-yl)-4-[4-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-2-yl]morpholine;3-[2-[(3S,5S)-3-methyl-5-(1H-pyrazol-4-yl)piperidin-1-yl]pyrimidin-4-yl]-6-(trifluoromethyl)imidazo[1,2-a]pyridine;N-[[1-[3-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]-1,2,4-thiadiazol-5-yl]piperidin-3-yl]methyl]methanesulfonamide
• PubChem CID: 157207572
• Molecular Formula: C100H101ClF12N30O7S3
• Molecular Weight: 2194.74 g/mol
• Exact Mass: 2192.71
• IUPAC Name: (2R)-4-[6-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrazin-2-yl]-2-(2-methylsulfonylethyl)morpholine;(2R,6S)-2-methyl-6-(3-methyl-2H-pyrrol-4-yl)-4-[4-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-2-yl]morpholine;(2S,6R)-2-methyl-6-(3-methyl-2H-pyrrol-4-yl)-4-[4-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-2-yl]morpholine;3-[2-[(3S,5S)-3-methyl-5-(1H-pyrazol-4-yl)piperidin-1-yl]pyrimidin-4-yl]-6-(trifluoromethyl)imidazo[1,2-a]pyridine;N-[[1-[3-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]-1,2,4-thiadiazol-5-yl]piperidin-3-yl]methyl]methanesulfonamide
• SMILES: CC1=C([C@@H]2CN(c3nccc(-c4cnc5ccc(C(F)(F)F)cn45)n3)C[C@H](C)O2)C=NC1.CC1=C([C@H]2CN(c3nccc(-c4cnc5ccc(C(F)(F)F)cn45)n3)C[C@@H](C)O2)C=NC1.CS(=O)(=O)CC[C@@H]1CN(c2cncc(-c3cnc4ccc(Cl)cn34)n2)CCO1.CS(=O)(=O)NCC1CCCN(c2nc(-c3cnc4ccc(C(F)(F)F)cn34)ns2)C1.C[C@H]1C[C@@H](c2cn[nH]c2)CN(c2nccc(-c3cnc4ccc(C(F)(F)F)cn34)n2)C1
• InChI: InChI=1S/2C22H21F3N6O.C21H20F3N7.C18H20ClN5O3S.C17H19F3N6O2S2/c2*1-13-7-26-8-16(13)19-12-30(10-14(2)32-19)21-27-6-5-17(29-21)18-9-28-20-4-3-15(11-31(18)20)22(23,24)25;1-13-6-14(15-7-27-28-8-15)11-30(10-13)20-25-5-4-17(29-20)18-9-26-19-3-2-16(12-31(18)19)21(22,23)24;1-28(25,26)7-4-14-12-23(5-6-27-14)18-10-20-8-15(22-18)16-9-21-17-3-2-13(19)11-24(16)17;1-30(27,28)22-7-11-3-2-6-25(9-11)16-23-15(24-29-16)13-8-21-14-5-4-12(10-26(13)14)17(18,19)20/h2*3-6,8-9,11,14,19H,7,10,12H2,1-2H3;2-5,7-9,12-14H,6,10-11H2,1H3,(H,27,28);2-3,8-11,14H,4-7,12H2,1H3;4-5,8,10-11,22H,2-3,6-7,9H2,1H3/t2*14-,19-;13-,14+;14-;/m1001./s1
• InChIKey: ARNHNCPWKJJRLW-BQUSAWOTSA-N
• XLogP: 16.49
• TPSA: 393.00 Ų
• H-Bond Donors: 2
• H-Bond Acceptors: 36
• Rotatable Bonds: 19
• Heavy Atoms: 153
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	2194.74
LogP ≤ 5	16.49
H-Bond Donors ≤ 5	2
H-Bond Acceptors ≤ 10	36

Frequently Asked Questions

What is the IUPAC name of (2R)-4-[6-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrazin-2-yl]-2-(2-methylsulfonylethyl)morpholine;(2R,6S)-2-methyl-6-(3-methyl-2H-pyrrol-4-yl)-4-[4-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-2-yl]morpholine;(2S,6R)-2-methyl-6-(3-methyl-2H-pyrrol-4-yl)-4-[4-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-2-yl]morpholine;3-[2-[(3S,5S)-3-methyl-5-(1H-pyrazol-4-yl)piperidin-1-yl]pyrimidin-4-yl]-6-(trifluoromethyl)imidazo[1,2-a]pyridine;N-[[1-[3-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]-1,2,4-thiadiazol-5-yl]piperidin-3-yl]methyl]methanesulfonamide?

The IUPAC name of (2R)-4-[6-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrazin-2-yl]-2-(2-methylsulfonylethyl)morpholine;(2R,6S)-2-methyl-6-(3-methyl-2H-pyrrol-4-yl)-4-[4-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-2-yl]morpholine;(2S,6R)-2-methyl-6-(3-methyl-2H-pyrrol-4-yl)-4-[4-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-2-yl]morpholine;3-[2-[(3S,5S)-3-methyl-5-(1H-pyrazol-4-yl)piperidin-1-yl]pyrimidin-4-yl]-6-(trifluoromethyl)imidazo[1,2-a]pyridine;N-[[1-[3-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]-1,2,4-thiadiazol-5-yl]piperidin-3-yl]methyl]methanesulfonamide (CID 157207572) is (2R)-4-[6-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrazin-2-yl]-2-(2-methylsulfonylethyl)morpholine;(2R,6S)-2-methyl-6-(3-methyl-2H-pyrrol-4-yl)-4-[4-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-2-yl]morpholine;(2S,6R)-2-methyl-6-(3-methyl-2H-pyrrol-4-yl)-4-[4-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-2-yl]morpholine;3-[2-[(3S,5S)-3-methyl-5-(1H-pyrazol-4-yl)piperidin-1-yl]pyrimidin-4-yl]-6-(trifluoromethyl)imidazo[1,2-a]pyridine;N-[[1-[3-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]-1,2,4-thiadiazol-5-yl]piperidin-3-yl]methyl]methanesulfonamide.

What is the SMILES notation for (2R)-4-[6-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrazin-2-yl]-2-(2-methylsulfonylethyl)morpholine;(2R,6S)-2-methyl-6-(3-methyl-2H-pyrrol-4-yl)-4-[4-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-2-yl]morpholine;(2S,6R)-2-methyl-6-(3-methyl-2H-pyrrol-4-yl)-4-[4-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-2-yl]morpholine;3-[2-[(3S,5S)-3-methyl-5-(1H-pyrazol-4-yl)piperidin-1-yl]pyrimidin-4-yl]-6-(trifluoromethyl)imidazo[1,2-a]pyridine;N-[[1-[3-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]-1,2,4-thiadiazol-5-yl]piperidin-3-yl]methyl]methanesulfonamide?

The canonical SMILES for (2R)-4-[6-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrazin-2-yl]-2-(2-methylsulfonylethyl)morpholine;(2R,6S)-2-methyl-6-(3-methyl-2H-pyrrol-4-yl)-4-[4-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-2-yl]morpholine;(2S,6R)-2-methyl-6-(3-methyl-2H-pyrrol-4-yl)-4-[4-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-2-yl]morpholine;3-[2-[(3S,5S)-3-methyl-5-(1H-pyrazol-4-yl)piperidin-1-yl]pyrimidin-4-yl]-6-(trifluoromethyl)imidazo[1,2-a]pyridine;N-[[1-[3-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]-1,2,4-thiadiazol-5-yl]piperidin-3-yl]methyl]methanesulfonamide is CC1=C([C@@H]2CN(c3nccc(-c4cnc5ccc(C(F)(F)F)cn45)n3)C[C@H](C)O2)C=NC1.CC1=C([C@H]2CN(c3nccc(-c4cnc5ccc(C(F)(F)F)cn45)n3)C[C@@H](C)O2)C=NC1.CS(=O)(=O)CC[C@@H]1CN(c2cncc(-c3cnc4ccc(Cl)cn34)n2)CCO1.CS(=O)(=O)NCC1CCCN(c2nc(-c3cnc4ccc(C(F)(F)F)cn34)ns2)C1.C[C@H]1C[C@@H](c2cn[nH]c2)CN(c2nccc(-c3cnc4ccc(C(F)(F)F)cn34)n2)C1.

What is the InChIKey of (2R)-4-[6-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrazin-2-yl]-2-(2-methylsulfonylethyl)morpholine;(2R,6S)-2-methyl-6-(3-methyl-2H-pyrrol-4-yl)-4-[4-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-2-yl]morpholine;(2S,6R)-2-methyl-6-(3-methyl-2H-pyrrol-4-yl)-4-[4-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-2-yl]morpholine;3-[2-[(3S,5S)-3-methyl-5-(1H-pyrazol-4-yl)piperidin-1-yl]pyrimidin-4-yl]-6-(trifluoromethyl)imidazo[1,2-a]pyridine;N-[[1-[3-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]-1,2,4-thiadiazol-5-yl]piperidin-3-yl]methyl]methanesulfonamide?

The InChIKey is ARNHNCPWKJJRLW-BQUSAWOTSA-N. The full InChI is InChI=1S/2C22H21F3N6O.C21H20F3N7.C18H20ClN5O3S.C17H19F3N6O2S2/c2*1-13-7-26-8-16(13)19-12-30(10-14(2)32-19)21-27-6-5-17(29-21)18-9-28-20-4-3-15(11-31(18)20)22(23,24)25;1-13-6-14(15-7-27-28-8-15)11-30(10-13)20-25-5-4-17(29-20)18-9-26-19-3-2-16(12-31(18)19)21(22,23)24;1-28(25,26)7-4-14-12-23(5-6-27-14)18-10-20-8-15(22-18)16-9-21-17-3-2-13(19)11-24(16)17;1-30(27,28)22-7-11-3-2-6-25(9-11)16-23-15(24-29-16)13-8-21-14-5-4-12(10-26(13)14)17(18,19)20/h2*3-6,8-9,11,14,19H,7,10,12H2,1-2H3;2-5,7-9,12-14H,6,10-11H2,1H3,(H,27,28);2-3,8-11,14H,4-7,12H2,1H3;4-5,8,10-11,22H,2-3,6-7,9H2,1H3/t2*14-,19-;13-,14+;14-;/m1001./s1.

What are the key properties of (2R)-4-[6-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrazin-2-yl]-2-(2-methylsulfonylethyl)morpholine;(2R,6S)-2-methyl-6-(3-methyl-2H-pyrrol-4-yl)-4-[4-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-2-yl]morpholine;(2S,6R)-2-methyl-6-(3-methyl-2H-pyrrol-4-yl)-4-[4-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-2-yl]morpholine;3-[2-[(3S,5S)-3-methyl-5-(1H-pyrazol-4-yl)piperidin-1-yl]pyrimidin-4-yl]-6-(trifluoromethyl)imidazo[1,2-a]pyridine;N-[[1-[3-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]-1,2,4-thiadiazol-5-yl]piperidin-3-yl]methyl]methanesulfonamide?

(2R)-4-[6-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrazin-2-yl]-2-(2-methylsulfonylethyl)morpholine;(2R,6S)-2-methyl-6-(3-methyl-2H-pyrrol-4-yl)-4-[4-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-2-yl]morpholine;(2S,6R)-2-methyl-6-(3-methyl-2H-pyrrol-4-yl)-4-[4-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-2-yl]morpholine;3-[2-[(3S,5S)-3-methyl-5-(1H-pyrazol-4-yl)piperidin-1-yl]pyrimidin-4-yl]-6-(trifluoromethyl)imidazo[1,2-a]pyridine;N-[[1-[3-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]-1,2,4-thiadiazol-5-yl]piperidin-3-yl]methyl]methanesulfonamide has a molecular weight of 2194.74 g/mol, XLogP of 16.49, 19 rotatable bonds, 2 hydrogen bond donors, and 36 hydrogen bond acceptors.

Where does this data come from?

All data for (2R)-4-[6-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrazin-2-yl]-2-(2-methylsulfonylethyl)morpholine;(2R,6S)-2-methyl-6-(3-methyl-2H-pyrrol-4-yl)-4-[4-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-2-yl]morpholine;(2S,6R)-2-methyl-6-(3-methyl-2H-pyrrol-4-yl)-4-[4-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-2-yl]morpholine;3-[2-[(3S,5S)-3-methyl-5-(1H-pyrazol-4-yl)piperidin-1-yl]pyrimidin-4-yl]-6-(trifluoromethyl)imidazo[1,2-a]pyridine;N-[[1-[3-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]-1,2,4-thiadiazol-5-yl]piperidin-3-yl]methyl]methanesulfonamide is sourced from PubChem (CID 157207572), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).