8-chloro-2-cyclopropyl-4-methoxyquinazoline;8-chloro-2-cyclopropyloxy-4-methoxyquinazoline;5-chloro-1,6-dimethoxy-3-pyrazol-1-ylisoquinoline;8-chloro-4,7-dimethoxy-2-pyridin-4-ylquinazoline;4-(8-chloro-4,7-dimethoxyquinazolin-2-yl)morpholine;8-chloro-2-imidazol-1-yl-4,7-dimethoxyquinazoline;8-chloro-4-methoxy-2-pyridin-4-ylquinazoline;8-chloro-4-methoxy-2-(trifluoromethyl)quinazoline

C104H89Cl8F3N22O14 — CID 157218043

About 8-chloro-2-cyclopropyl-4-methoxyquinazoline;8-chloro-2-cyclopropyloxy-4-methoxyquinazoline;5-chloro-1,6-dimethoxy-3-pyrazol-1-ylisoquinoline;8-chloro-4,7-dimethoxy-2-pyridin-4-ylquinazoline;4-(8-chloro-4,7-dimethoxyquinazolin-2-yl)morpholine;8-chloro-2-imidazol-1-yl-4,7-dimethoxyquinazoline;8-chloro-4-methoxy-2-pyridin-4-ylquinazoline;8-chloro-4-methoxy-2-(trifluoromethyl)quinazoline

8-chloro-2-cyclopropyl-4-methoxyquinazoline;8-chloro-2-cyclopropyloxy-4-methoxyquinazoline;5-chloro-1,6-dimethoxy-3-pyrazol-1-ylisoquinoline;8-chloro-4,7-dimethoxy-2-pyridin-4-ylquinazoline;4-(8-chloro-4,7-dimethoxyquinazolin-2-yl)morpholine;8-chloro-2-imidazol-1-yl-4,7-dimethoxyquinazoline;8-chloro-4-methoxy-2-pyridin-4-ylquinazoline;8-chloro-4-methoxy-2-(trifluoromethyl)quinazoline (PubChem CID 157218043) has the molecular formula C104H89Cl8F3N22O14 and a molecular weight of 2211.61 g/mol. Its IUPAC name is 8-chloro-2-cyclopropyl-4-methoxyquinazoline;8-chloro-2-cyclopropyloxy-4-methoxyquinazoline;5-chloro-1,6-dimethoxy-3-pyrazol-1-ylisoquinoline;8-chloro-4,7-dimethoxy-2-pyridin-4-ylquinazoline;4-(8-chloro-4,7-dimethoxyquinazolin-2-yl)morpholine;8-chloro-2-imidazol-1-yl-4,7-dimethoxyquinazoline;8-chloro-4-methoxy-2-pyridin-4-ylquinazoline;8-chloro-4-methoxy-2-(trifluoromethyl)quinazoline.

Molecular Properties

• Compound Name: 8-chloro-2-cyclopropyl-4-methoxyquinazoline;8-chloro-2-cyclopropyloxy-4-methoxyquinazoline;5-chloro-1,6-dimethoxy-3-pyrazol-1-ylisoquinoline;8-chloro-4,7-dimethoxy-2-pyridin-4-ylquinazoline;4-(8-chloro-4,7-dimethoxyquinazolin-2-yl)morpholine;8-chloro-2-imidazol-1-yl-4,7-dimethoxyquinazoline;8-chloro-4-methoxy-2-pyridin-4-ylquinazoline;8-chloro-4-methoxy-2-(trifluoromethyl)quinazoline
• PubChem CID: 157218043
• Molecular Formula: C104H89Cl8F3N22O14
• Molecular Weight: 2211.61 g/mol
• Exact Mass: 2206.44
• IUPAC Name: 8-chloro-2-cyclopropyl-4-methoxyquinazoline;8-chloro-2-cyclopropyloxy-4-methoxyquinazoline;5-chloro-1,6-dimethoxy-3-pyrazol-1-ylisoquinoline;8-chloro-4,7-dimethoxy-2-pyridin-4-ylquinazoline;4-(8-chloro-4,7-dimethoxyquinazolin-2-yl)morpholine;8-chloro-2-imidazol-1-yl-4,7-dimethoxyquinazoline;8-chloro-4-methoxy-2-pyridin-4-ylquinazoline;8-chloro-4-methoxy-2-(trifluoromethyl)quinazoline
• SMILES: COc1ccc2c(OC)nc(-c3ccncc3)nc2c1Cl.COc1ccc2c(OC)nc(-n3cccn3)cc2c1Cl.COc1ccc2c(OC)nc(-n3ccnc3)nc2c1Cl.COc1ccc2c(OC)nc(N3CCOCC3)nc2c1Cl.COc1nc(-c2ccncc2)nc2c(Cl)cccc12.COc1nc(C(F)(F)F)nc2c(Cl)cccc12.COc1nc(C2CC2)nc2c(Cl)cccc12.COc1nc(OC2CC2)nc2c(Cl)cccc12
• InChI: InChI=1S/C15H12ClN3O2.C14H16ClN3O3.C14H12ClN3O2.C14H10ClN3O.C13H11ClN4O2.C12H11ClN2O2.C12H11ClN2O.C10H6ClF3N2O/c1-20-11-4-3-10-13(12(11)16)18-14(19-15(10)21-2)9-5-7-17-8-6-9;1-19-10-4-3-9-12(11(10)15)16-14(17-13(9)20-2)18-5-7-21-8-6-18;1-19-11-5-4-9-10(13(11)15)8-12(17-14(9)20-2)18-7-3-6-16-18;1-19-14-10-3-2-4-11(15)12(10)17-13(18-14)9-5-7-16-8-6-9;1-19-9-4-3-8-11(10(9)14)16-13(17-12(8)20-2)18-6-5-15-7-18;1-16-11-8-3-2-4-9(13)10(8)14-12(15-11)17-7-5-6-7;1-16-12-8-3-2-4-9(13)10(8)14-11(15-12)7-5-6-7;1-17-8-5-3-2-4-6(11)7(5)15-9(16-8)10(12,13)14/h3-8H,1-2H3;3-4H,5-8H2,1-2H3;3-8H,1-2H3;2-8H,1H3;3-7H,1-2H3;2-4,7H,5-6H2,1H3;2-4,7H,5-6H2,1H3;2-4H,1H3
• InChIKey: ASQOTGZWLRIHBF-UHFFFAOYSA-N
• XLogP: 23.74
• TPSA: 387.23 Ų
• H-Bond Acceptors: 36
• Rotatable Bonds: 20
• Heavy Atoms: 151
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	2211.61
LogP ≤ 5	23.74
H-Bond Donors ≤ 5	0
H-Bond Acceptors ≤ 10	36

Frequently Asked Questions

What is the IUPAC name of 8-chloro-2-cyclopropyl-4-methoxyquinazoline;8-chloro-2-cyclopropyloxy-4-methoxyquinazoline;5-chloro-1,6-dimethoxy-3-pyrazol-1-ylisoquinoline;8-chloro-4,7-dimethoxy-2-pyridin-4-ylquinazoline;4-(8-chloro-4,7-dimethoxyquinazolin-2-yl)morpholine;8-chloro-2-imidazol-1-yl-4,7-dimethoxyquinazoline;8-chloro-4-methoxy-2-pyridin-4-ylquinazoline;8-chloro-4-methoxy-2-(trifluoromethyl)quinazoline?

The IUPAC name of 8-chloro-2-cyclopropyl-4-methoxyquinazoline;8-chloro-2-cyclopropyloxy-4-methoxyquinazoline;5-chloro-1,6-dimethoxy-3-pyrazol-1-ylisoquinoline;8-chloro-4,7-dimethoxy-2-pyridin-4-ylquinazoline;4-(8-chloro-4,7-dimethoxyquinazolin-2-yl)morpholine;8-chloro-2-imidazol-1-yl-4,7-dimethoxyquinazoline;8-chloro-4-methoxy-2-pyridin-4-ylquinazoline;8-chloro-4-methoxy-2-(trifluoromethyl)quinazoline (CID 157218043) is 8-chloro-2-cyclopropyl-4-methoxyquinazoline;8-chloro-2-cyclopropyloxy-4-methoxyquinazoline;5-chloro-1,6-dimethoxy-3-pyrazol-1-ylisoquinoline;8-chloro-4,7-dimethoxy-2-pyridin-4-ylquinazoline;4-(8-chloro-4,7-dimethoxyquinazolin-2-yl)morpholine;8-chloro-2-imidazol-1-yl-4,7-dimethoxyquinazoline;8-chloro-4-methoxy-2-pyridin-4-ylquinazoline;8-chloro-4-methoxy-2-(trifluoromethyl)quinazoline.

What is the SMILES notation for 8-chloro-2-cyclopropyl-4-methoxyquinazoline;8-chloro-2-cyclopropyloxy-4-methoxyquinazoline;5-chloro-1,6-dimethoxy-3-pyrazol-1-ylisoquinoline;8-chloro-4,7-dimethoxy-2-pyridin-4-ylquinazoline;4-(8-chloro-4,7-dimethoxyquinazolin-2-yl)morpholine;8-chloro-2-imidazol-1-yl-4,7-dimethoxyquinazoline;8-chloro-4-methoxy-2-pyridin-4-ylquinazoline;8-chloro-4-methoxy-2-(trifluoromethyl)quinazoline?

The canonical SMILES for 8-chloro-2-cyclopropyl-4-methoxyquinazoline;8-chloro-2-cyclopropyloxy-4-methoxyquinazoline;5-chloro-1,6-dimethoxy-3-pyrazol-1-ylisoquinoline;8-chloro-4,7-dimethoxy-2-pyridin-4-ylquinazoline;4-(8-chloro-4,7-dimethoxyquinazolin-2-yl)morpholine;8-chloro-2-imidazol-1-yl-4,7-dimethoxyquinazoline;8-chloro-4-methoxy-2-pyridin-4-ylquinazoline;8-chloro-4-methoxy-2-(trifluoromethyl)quinazoline is COc1ccc2c(OC)nc(-c3ccncc3)nc2c1Cl.COc1ccc2c(OC)nc(-n3cccn3)cc2c1Cl.COc1ccc2c(OC)nc(-n3ccnc3)nc2c1Cl.COc1ccc2c(OC)nc(N3CCOCC3)nc2c1Cl.COc1nc(-c2ccncc2)nc2c(Cl)cccc12.COc1nc(C(F)(F)F)nc2c(Cl)cccc12.COc1nc(C2CC2)nc2c(Cl)cccc12.COc1nc(OC2CC2)nc2c(Cl)cccc12.

What is the InChIKey of 8-chloro-2-cyclopropyl-4-methoxyquinazoline;8-chloro-2-cyclopropyloxy-4-methoxyquinazoline;5-chloro-1,6-dimethoxy-3-pyrazol-1-ylisoquinoline;8-chloro-4,7-dimethoxy-2-pyridin-4-ylquinazoline;4-(8-chloro-4,7-dimethoxyquinazolin-2-yl)morpholine;8-chloro-2-imidazol-1-yl-4,7-dimethoxyquinazoline;8-chloro-4-methoxy-2-pyridin-4-ylquinazoline;8-chloro-4-methoxy-2-(trifluoromethyl)quinazoline?

The InChIKey is ASQOTGZWLRIHBF-UHFFFAOYSA-N. The full InChI is InChI=1S/C15H12ClN3O2.C14H16ClN3O3.C14H12ClN3O2.C14H10ClN3O.C13H11ClN4O2.C12H11ClN2O2.C12H11ClN2O.C10H6ClF3N2O/c1-20-11-4-3-10-13(12(11)16)18-14(19-15(10)21-2)9-5-7-17-8-6-9;1-19-10-4-3-9-12(11(10)15)16-14(17-13(9)20-2)18-5-7-21-8-6-18;1-19-11-5-4-9-10(13(11)15)8-12(17-14(9)20-2)18-7-3-6-16-18;1-19-14-10-3-2-4-11(15)12(10)17-13(18-14)9-5-7-16-8-6-9;1-19-9-4-3-8-11(10(9)14)16-13(17-12(8)20-2)18-6-5-15-7-18;1-16-11-8-3-2-4-9(13)10(8)14-12(15-11)17-7-5-6-7;1-16-12-8-3-2-4-9(13)10(8)14-11(15-12)7-5-6-7;1-17-8-5-3-2-4-6(11)7(5)15-9(16-8)10(12,13)14/h3-8H,1-2H3;3-4H,5-8H2,1-2H3;3-8H,1-2H3;2-8H,1H3;3-7H,1-2H3;2-4,7H,5-6H2,1H3;2-4,7H,5-6H2,1H3;2-4H,1H3.

What are the key properties of 8-chloro-2-cyclopropyl-4-methoxyquinazoline;8-chloro-2-cyclopropyloxy-4-methoxyquinazoline;5-chloro-1,6-dimethoxy-3-pyrazol-1-ylisoquinoline;8-chloro-4,7-dimethoxy-2-pyridin-4-ylquinazoline;4-(8-chloro-4,7-dimethoxyquinazolin-2-yl)morpholine;8-chloro-2-imidazol-1-yl-4,7-dimethoxyquinazoline;8-chloro-4-methoxy-2-pyridin-4-ylquinazoline;8-chloro-4-methoxy-2-(trifluoromethyl)quinazoline?

8-chloro-2-cyclopropyl-4-methoxyquinazoline;8-chloro-2-cyclopropyloxy-4-methoxyquinazoline;5-chloro-1,6-dimethoxy-3-pyrazol-1-ylisoquinoline;8-chloro-4,7-dimethoxy-2-pyridin-4-ylquinazoline;4-(8-chloro-4,7-dimethoxyquinazolin-2-yl)morpholine;8-chloro-2-imidazol-1-yl-4,7-dimethoxyquinazoline;8-chloro-4-methoxy-2-pyridin-4-ylquinazoline;8-chloro-4-methoxy-2-(trifluoromethyl)quinazoline has a molecular weight of 2211.61 g/mol, XLogP of 23.74, 20 rotatable bonds, 0 hydrogen bond donors, and 36 hydrogen bond acceptors.

Where does this data come from?

All data for 8-chloro-2-cyclopropyl-4-methoxyquinazoline;8-chloro-2-cyclopropyloxy-4-methoxyquinazoline;5-chloro-1,6-dimethoxy-3-pyrazol-1-ylisoquinoline;8-chloro-4,7-dimethoxy-2-pyridin-4-ylquinazoline;4-(8-chloro-4,7-dimethoxyquinazolin-2-yl)morpholine;8-chloro-2-imidazol-1-yl-4,7-dimethoxyquinazoline;8-chloro-4-methoxy-2-pyridin-4-ylquinazoline;8-chloro-4-methoxy-2-(trifluoromethyl)quinazoline is sourced from PubChem (CID 157218043), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).