5-[5-[(4,4-difluoropiperidin-1-yl)methyl]-3-pyridinyl]-N-[3-[(dimethylamino)methyl]phenyl]-1H-indazole-3-carboxamide;5-[5-[(3,3-difluoropyrrolidin-1-yl)methyl]-3-pyridinyl]-N-[3-[(dimethylamino)methyl]phenyl]-1H-indazole-3-carboxamide;N-[3-[(dimethylamino)methyl]phenyl]-5-(5-piperidin-1-yl-3-pyridinyl)-1H-indazole-3-carboxamide;N-[3-[(dimethylamino)methyl]phenyl]-5-(5-pyrrolidin-1-yl-3-pyridinyl)-1H-indazole-3-carboxamide;N-(4-hydroxyphenyl)-5-[5-[(4-hydroxypiperidin-1-yl)methyl]-3-pyridinyl]-1H-indazole-3-carboxamide

C133H141F4N29O7 — CID 157236945

About 5-[5-[(4,4-difluoropiperidin-1-yl)methyl]-3-pyridinyl]-N-[3-[(dimethylamino)methyl]phenyl]-1H-indazole-3-carboxamide;5-[5-[(3,3-difluoropyrrolidin-1-yl)methyl]-3-pyridinyl]-N-[3-[(dimethylamino)methyl]phenyl]-1H-indazole-3-carboxamide;N-[3-[(dimethylamino)methyl]phenyl]-5-(5-piperidin-1-yl-3-pyridinyl)-1H-indazole-3-carboxamide;N-[3-[(dimethylamino)methyl]phenyl]-5-(5-pyrrolidin-1-yl-3-pyridinyl)-1H-indazole-3-carboxamide;N-(4-hydroxyphenyl)-5-[5-[(4-hydroxypiperidin-1-yl)methyl]-3-pyridinyl]-1H-indazole-3-carboxamide

5-[5-[(4,4-difluoropiperidin-1-yl)methyl]-3-pyridinyl]-N-[3-[(dimethylamino)methyl]phenyl]-1H-indazole-3-carboxamide;5-[5-[(3,3-difluoropyrrolidin-1-yl)methyl]-3-pyridinyl]-N-[3-[(dimethylamino)methyl]phenyl]-1H-indazole-3-carboxamide;N-[3-[(dimethylamino)methyl]phenyl]-5-(5-piperidin-1-yl-3-pyridinyl)-1H-indazole-3-carboxamide;N-[3-[(dimethylamino)methyl]phenyl]-5-(5-pyrrolidin-1-yl-3-pyridinyl)-1H-indazole-3-carboxamide;N-(4-hydroxyphenyl)-5-[5-[(4-hydroxypiperidin-1-yl)methyl]-3-pyridinyl]-1H-indazole-3-carboxamide (PubChem CID 157236945) has the molecular formula C133H141F4N29O7 and a molecular weight of 2333.78 g/mol. Its IUPAC name is 5-[5-[(4,4-difluoropiperidin-1-yl)methyl]-3-pyridinyl]-N-[3-[(dimethylamino)methyl]phenyl]-1H-indazole-3-carboxamide;5-[5-[(3,3-difluoropyrrolidin-1-yl)methyl]-3-pyridinyl]-N-[3-[(dimethylamino)methyl]phenyl]-1H-indazole-3-carboxamide;N-[3-[(dimethylamino)methyl]phenyl]-5-(5-piperidin-1-yl-3-pyridinyl)-1H-indazole-3-carboxamide;N-[3-[(dimethylamino)methyl]phenyl]-5-(5-pyrrolidin-1-yl-3-pyridinyl)-1H-indazole-3-carboxamide;N-(4-hydroxyphenyl)-5-[5-[(4-hydroxypiperidin-1-yl)methyl]-3-pyridinyl]-1H-indazole-3-carboxamide.

Molecular Properties

• Compound Name: 5-[5-[(4,4-difluoropiperidin-1-yl)methyl]-3-pyridinyl]-N-[3-[(dimethylamino)methyl]phenyl]-1H-indazole-3-carboxamide;5-[5-[(3,3-difluoropyrrolidin-1-yl)methyl]-3-pyridinyl]-N-[3-[(dimethylamino)methyl]phenyl]-1H-indazole-3-carboxamide;N-[3-[(dimethylamino)methyl]phenyl]-5-(5-piperidin-1-yl-3-pyridinyl)-1H-indazole-3-carboxamide;N-[3-[(dimethylamino)methyl]phenyl]-5-(5-pyrrolidin-1-yl-3-pyridinyl)-1H-indazole-3-carboxamide;N-(4-hydroxyphenyl)-5-[5-[(4-hydroxypiperidin-1-yl)methyl]-3-pyridinyl]-1H-indazole-3-carboxamide
• PubChem CID: 157236945
• Molecular Formula: C133H141F4N29O7
• Molecular Weight: 2333.78 g/mol
• Exact Mass: 2332.15
• IUPAC Name: 5-[5-[(4,4-difluoropiperidin-1-yl)methyl]-3-pyridinyl]-N-[3-[(dimethylamino)methyl]phenyl]-1H-indazole-3-carboxamide;5-[5-[(3,3-difluoropyrrolidin-1-yl)methyl]-3-pyridinyl]-N-[3-[(dimethylamino)methyl]phenyl]-1H-indazole-3-carboxamide;N-[3-[(dimethylamino)methyl]phenyl]-5-(5-piperidin-1-yl-3-pyridinyl)-1H-indazole-3-carboxamide;N-[3-[(dimethylamino)methyl]phenyl]-5-(5-pyrrolidin-1-yl-3-pyridinyl)-1H-indazole-3-carboxamide;N-(4-hydroxyphenyl)-5-[5-[(4-hydroxypiperidin-1-yl)methyl]-3-pyridinyl]-1H-indazole-3-carboxamide
• SMILES: CN(C)Cc1cccc(NC(=O)c2n[nH]c3ccc(-c4cncc(CN5CCC(F)(F)C5)c4)cc23)c1.CN(C)Cc1cccc(NC(=O)c2n[nH]c3ccc(-c4cncc(CN5CCC(F)(F)CC5)c4)cc23)c1.CN(C)Cc1cccc(NC(=O)c2n[nH]c3ccc(-c4cncc(N5CCCC5)c4)cc23)c1.CN(C)Cc1cccc(NC(=O)c2n[nH]c3ccc(-c4cncc(N5CCCCC5)c4)cc23)c1.O=C(Nc1ccc(O)cc1)c1n[nH]c2ccc(-c3cncc(CN4CCC(O)CC4)c3)cc12
• InChI: InChI=1S/C28H30F2N6O.C27H28F2N6O.C27H30N6O.C26H28N6O.C25H25N5O3/c1-35(2)17-19-4-3-5-23(13-19)32-27(37)26-24-14-21(6-7-25(24)33-34-26)22-12-20(15-31-16-22)18-36-10-8-28(29,30)9-11-36;1-34(2)15-18-4-3-5-22(11-18)31-26(36)25-23-12-20(6-7-24(23)32-33-25)21-10-19(13-30-14-21)16-35-9-8-27(28,29)17-35;1-32(2)18-19-7-6-8-22(13-19)29-27(34)26-24-15-20(9-10-25(24)30-31-26)21-14-23(17-28-16-21)33-11-4-3-5-12-33;1-31(2)17-18-6-5-7-21(12-18)28-26(33)25-23-14-19(8-9-24(23)29-30-25)20-13-22(16-27-15-20)32-10-3-4-11-32;31-20-4-2-19(3-5-20)27-25(33)24-22-12-17(1-6-23(22)28-29-24)18-11-16(13-26-14-18)15-30-9-7-21(32)8-10-30/h3-7,12-16H,8-11,17-18H2,1-2H3,(H,32,37)(H,33,34);3-7,10-14H,8-9,15-17H2,1-2H3,(H,31,36)(H,32,33);6-10,13-17H,3-5,11-12,18H2,1-2H3,(H,29,34)(H,30,31);5-9,12-16H,3-4,10-11,17H2,1-2H3,(H,28,33)(H,29,30);1-6,11-14,21,31-32H,7-10,15H2,(H,27,33)(H,28,29)
• InChIKey: AUSZMDAJCUHEEN-UHFFFAOYSA-N
• XLogP: 22.96
• TPSA: 422.97 Ų
• H-Bond Donors: 12
• H-Bond Acceptors: 26
• Rotatable Bonds: 31
• Heavy Atoms: 173
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2333.78
LogP ≤ 5	22.96
H-Bond Donors ≤ 5	12
H-Bond Acceptors ≤ 10	26

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': 'hydroquinone', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of 5-[5-[(4,4-difluoropiperidin-1-yl)methyl]-3-pyridinyl]-N-[3-[(dimethylamino)methyl]phenyl]-1H-indazole-3-carboxamide;5-[5-[(3,3-difluoropyrrolidin-1-yl)methyl]-3-pyridinyl]-N-[3-[(dimethylamino)methyl]phenyl]-1H-indazole-3-carboxamide;N-[3-[(dimethylamino)methyl]phenyl]-5-(5-piperidin-1-yl-3-pyridinyl)-1H-indazole-3-carboxamide;N-[3-[(dimethylamino)methyl]phenyl]-5-(5-pyrrolidin-1-yl-3-pyridinyl)-1H-indazole-3-carboxamide;N-(4-hydroxyphenyl)-5-[5-[(4-hydroxypiperidin-1-yl)methyl]-3-pyridinyl]-1H-indazole-3-carboxamide?

The IUPAC name of 5-[5-[(4,4-difluoropiperidin-1-yl)methyl]-3-pyridinyl]-N-[3-[(dimethylamino)methyl]phenyl]-1H-indazole-3-carboxamide;5-[5-[(3,3-difluoropyrrolidin-1-yl)methyl]-3-pyridinyl]-N-[3-[(dimethylamino)methyl]phenyl]-1H-indazole-3-carboxamide;N-[3-[(dimethylamino)methyl]phenyl]-5-(5-piperidin-1-yl-3-pyridinyl)-1H-indazole-3-carboxamide;N-[3-[(dimethylamino)methyl]phenyl]-5-(5-pyrrolidin-1-yl-3-pyridinyl)-1H-indazole-3-carboxamide;N-(4-hydroxyphenyl)-5-[5-[(4-hydroxypiperidin-1-yl)methyl]-3-pyridinyl]-1H-indazole-3-carboxamide (CID 157236945) is 5-[5-[(4,4-difluoropiperidin-1-yl)methyl]-3-pyridinyl]-N-[3-[(dimethylamino)methyl]phenyl]-1H-indazole-3-carboxamide;5-[5-[(3,3-difluoropyrrolidin-1-yl)methyl]-3-pyridinyl]-N-[3-[(dimethylamino)methyl]phenyl]-1H-indazole-3-carboxamide;N-[3-[(dimethylamino)methyl]phenyl]-5-(5-piperidin-1-yl-3-pyridinyl)-1H-indazole-3-carboxamide;N-[3-[(dimethylamino)methyl]phenyl]-5-(5-pyrrolidin-1-yl-3-pyridinyl)-1H-indazole-3-carboxamide;N-(4-hydroxyphenyl)-5-[5-[(4-hydroxypiperidin-1-yl)methyl]-3-pyridinyl]-1H-indazole-3-carboxamide.

What is the SMILES notation for 5-[5-[(4,4-difluoropiperidin-1-yl)methyl]-3-pyridinyl]-N-[3-[(dimethylamino)methyl]phenyl]-1H-indazole-3-carboxamide;5-[5-[(3,3-difluoropyrrolidin-1-yl)methyl]-3-pyridinyl]-N-[3-[(dimethylamino)methyl]phenyl]-1H-indazole-3-carboxamide;N-[3-[(dimethylamino)methyl]phenyl]-5-(5-piperidin-1-yl-3-pyridinyl)-1H-indazole-3-carboxamide;N-[3-[(dimethylamino)methyl]phenyl]-5-(5-pyrrolidin-1-yl-3-pyridinyl)-1H-indazole-3-carboxamide;N-(4-hydroxyphenyl)-5-[5-[(4-hydroxypiperidin-1-yl)methyl]-3-pyridinyl]-1H-indazole-3-carboxamide?

The canonical SMILES for 5-[5-[(4,4-difluoropiperidin-1-yl)methyl]-3-pyridinyl]-N-[3-[(dimethylamino)methyl]phenyl]-1H-indazole-3-carboxamide;5-[5-[(3,3-difluoropyrrolidin-1-yl)methyl]-3-pyridinyl]-N-[3-[(dimethylamino)methyl]phenyl]-1H-indazole-3-carboxamide;N-[3-[(dimethylamino)methyl]phenyl]-5-(5-piperidin-1-yl-3-pyridinyl)-1H-indazole-3-carboxamide;N-[3-[(dimethylamino)methyl]phenyl]-5-(5-pyrrolidin-1-yl-3-pyridinyl)-1H-indazole-3-carboxamide;N-(4-hydroxyphenyl)-5-[5-[(4-hydroxypiperidin-1-yl)methyl]-3-pyridinyl]-1H-indazole-3-carboxamide is CN(C)Cc1cccc(NC(=O)c2n[nH]c3ccc(-c4cncc(CN5CCC(F)(F)C5)c4)cc23)c1.CN(C)Cc1cccc(NC(=O)c2n[nH]c3ccc(-c4cncc(CN5CCC(F)(F)CC5)c4)cc23)c1.CN(C)Cc1cccc(NC(=O)c2n[nH]c3ccc(-c4cncc(N5CCCC5)c4)cc23)c1.CN(C)Cc1cccc(NC(=O)c2n[nH]c3ccc(-c4cncc(N5CCCCC5)c4)cc23)c1.O=C(Nc1ccc(O)cc1)c1n[nH]c2ccc(-c3cncc(CN4CCC(O)CC4)c3)cc12.

What is the InChIKey of 5-[5-[(4,4-difluoropiperidin-1-yl)methyl]-3-pyridinyl]-N-[3-[(dimethylamino)methyl]phenyl]-1H-indazole-3-carboxamide;5-[5-[(3,3-difluoropyrrolidin-1-yl)methyl]-3-pyridinyl]-N-[3-[(dimethylamino)methyl]phenyl]-1H-indazole-3-carboxamide;N-[3-[(dimethylamino)methyl]phenyl]-5-(5-piperidin-1-yl-3-pyridinyl)-1H-indazole-3-carboxamide;N-[3-[(dimethylamino)methyl]phenyl]-5-(5-pyrrolidin-1-yl-3-pyridinyl)-1H-indazole-3-carboxamide;N-(4-hydroxyphenyl)-5-[5-[(4-hydroxypiperidin-1-yl)methyl]-3-pyridinyl]-1H-indazole-3-carboxamide?

The InChIKey is AUSZMDAJCUHEEN-UHFFFAOYSA-N. The full InChI is InChI=1S/C28H30F2N6O.C27H28F2N6O.C27H30N6O.C26H28N6O.C25H25N5O3/c1-35(2)17-19-4-3-5-23(13-19)32-27(37)26-24-14-21(6-7-25(24)33-34-26)22-12-20(15-31-16-22)18-36-10-8-28(29,30)9-11-36;1-34(2)15-18-4-3-5-22(11-18)31-26(36)25-23-12-20(6-7-24(23)32-33-25)21-10-19(13-30-14-21)16-35-9-8-27(28,29)17-35;1-32(2)18-19-7-6-8-22(13-19)29-27(34)26-24-15-20(9-10-25(24)30-31-26)21-14-23(17-28-16-21)33-11-4-3-5-12-33;1-31(2)17-18-6-5-7-21(12-18)28-26(33)25-23-14-19(8-9-24(23)29-30-25)20-13-22(16-27-15-20)32-10-3-4-11-32;31-20-4-2-19(3-5-20)27-25(33)24-22-12-17(1-6-23(22)28-29-24)18-11-16(13-26-14-18)15-30-9-7-21(32)8-10-30/h3-7,12-16H,8-11,17-18H2,1-2H3,(H,32,37)(H,33,34);3-7,10-14H,8-9,15-17H2,1-2H3,(H,31,36)(H,32,33);6-10,13-17H,3-5,11-12,18H2,1-2H3,(H,29,34)(H,30,31);5-9,12-16H,3-4,10-11,17H2,1-2H3,(H,28,33)(H,29,30);1-6,11-14,21,31-32H,7-10,15H2,(H,27,33)(H,28,29).

What are the key properties of 5-[5-[(4,4-difluoropiperidin-1-yl)methyl]-3-pyridinyl]-N-[3-[(dimethylamino)methyl]phenyl]-1H-indazole-3-carboxamide;5-[5-[(3,3-difluoropyrrolidin-1-yl)methyl]-3-pyridinyl]-N-[3-[(dimethylamino)methyl]phenyl]-1H-indazole-3-carboxamide;N-[3-[(dimethylamino)methyl]phenyl]-5-(5-piperidin-1-yl-3-pyridinyl)-1H-indazole-3-carboxamide;N-[3-[(dimethylamino)methyl]phenyl]-5-(5-pyrrolidin-1-yl-3-pyridinyl)-1H-indazole-3-carboxamide;N-(4-hydroxyphenyl)-5-[5-[(4-hydroxypiperidin-1-yl)methyl]-3-pyridinyl]-1H-indazole-3-carboxamide?

5-[5-[(4,4-difluoropiperidin-1-yl)methyl]-3-pyridinyl]-N-[3-[(dimethylamino)methyl]phenyl]-1H-indazole-3-carboxamide;5-[5-[(3,3-difluoropyrrolidin-1-yl)methyl]-3-pyridinyl]-N-[3-[(dimethylamino)methyl]phenyl]-1H-indazole-3-carboxamide;N-[3-[(dimethylamino)methyl]phenyl]-5-(5-piperidin-1-yl-3-pyridinyl)-1H-indazole-3-carboxamide;N-[3-[(dimethylamino)methyl]phenyl]-5-(5-pyrrolidin-1-yl-3-pyridinyl)-1H-indazole-3-carboxamide;N-(4-hydroxyphenyl)-5-[5-[(4-hydroxypiperidin-1-yl)methyl]-3-pyridinyl]-1H-indazole-3-carboxamide has a molecular weight of 2333.78 g/mol, XLogP of 22.96, 31 rotatable bonds, 12 hydrogen bond donors, and 26 hydrogen bond acceptors.

Where does this data come from?

All data for 5-[5-[(4,4-difluoropiperidin-1-yl)methyl]-3-pyridinyl]-N-[3-[(dimethylamino)methyl]phenyl]-1H-indazole-3-carboxamide;5-[5-[(3,3-difluoropyrrolidin-1-yl)methyl]-3-pyridinyl]-N-[3-[(dimethylamino)methyl]phenyl]-1H-indazole-3-carboxamide;N-[3-[(dimethylamino)methyl]phenyl]-5-(5-piperidin-1-yl-3-pyridinyl)-1H-indazole-3-carboxamide;N-[3-[(dimethylamino)methyl]phenyl]-5-(5-pyrrolidin-1-yl-3-pyridinyl)-1H-indazole-3-carboxamide;N-(4-hydroxyphenyl)-5-[5-[(4-hydroxypiperidin-1-yl)methyl]-3-pyridinyl]-1H-indazole-3-carboxamide is sourced from PubChem (CID 157236945), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).