N-[[3-fluoro-4-(2-methyl-4-pyridinyl)phenyl]methyl]-2-(2-methyl-4-pyridinyl)pyrido[3,4-b]pyrazin-5-amine;N-[[5-methyl-6-(3-methylphenyl)-3-pyridinyl]methyl]-6-pyrazin-2-yl-2,7-naphthyridin-1-amine;N-[[3-methyl-4-(2-methyl-4-pyridinyl)phenyl]methyl]-2-(2-methyl-4-pyridinyl)pyrido[3,4-b]pyrazin-5-amine;2-(2-methyl-4-pyridinyl)-N-[[6-(2-methyl-4-pyridinyl)-3-pyridinyl]methyl]pyrido[3,4-b]pyrazin-5-amine

C104H88FN25 — CID 157239491

About N-[[3-fluoro-4-(2-methyl-4-pyridinyl)phenyl]methyl]-2-(2-methyl-4-pyridinyl)pyrido[3,4-b]pyrazin-5-amine;N-[[5-methyl-6-(3-methylphenyl)-3-pyridinyl]methyl]-6-pyrazin-2-yl-2,7-naphthyridin-1-amine;N-[[3-methyl-4-(2-methyl-4-pyridinyl)phenyl]methyl]-2-(2-methyl-4-pyridinyl)pyrido[3,4-b]pyrazin-5-amine;2-(2-methyl-4-pyridinyl)-N-[[6-(2-methyl-4-pyridinyl)-3-pyridinyl]methyl]pyrido[3,4-b]pyrazin-5-amine

N-[[3-fluoro-4-(2-methyl-4-pyridinyl)phenyl]methyl]-2-(2-methyl-4-pyridinyl)pyrido[3,4-b]pyrazin-5-amine;N-[[5-methyl-6-(3-methylphenyl)-3-pyridinyl]methyl]-6-pyrazin-2-yl-2,7-naphthyridin-1-amine;N-[[3-methyl-4-(2-methyl-4-pyridinyl)phenyl]methyl]-2-(2-methyl-4-pyridinyl)pyrido[3,4-b]pyrazin-5-amine;2-(2-methyl-4-pyridinyl)-N-[[6-(2-methyl-4-pyridinyl)-3-pyridinyl]methyl]pyrido[3,4-b]pyrazin-5-amine (PubChem CID 157239491) has the molecular formula C104H88FN25 and a molecular weight of 1707.02 g/mol. Its IUPAC name is N-[[3-fluoro-4-(2-methyl-4-pyridinyl)phenyl]methyl]-2-(2-methyl-4-pyridinyl)pyrido[3,4-b]pyrazin-5-amine;N-[[5-methyl-6-(3-methylphenyl)-3-pyridinyl]methyl]-6-pyrazin-2-yl-2,7-naphthyridin-1-amine;N-[[3-methyl-4-(2-methyl-4-pyridinyl)phenyl]methyl]-2-(2-methyl-4-pyridinyl)pyrido[3,4-b]pyrazin-5-amine;2-(2-methyl-4-pyridinyl)-N-[[6-(2-methyl-4-pyridinyl)-3-pyridinyl]methyl]pyrido[3,4-b]pyrazin-5-amine.

Molecular Properties

• Compound Name: N-[[3-fluoro-4-(2-methyl-4-pyridinyl)phenyl]methyl]-2-(2-methyl-4-pyridinyl)pyrido[3,4-b]pyrazin-5-amine;N-[[5-methyl-6-(3-methylphenyl)-3-pyridinyl]methyl]-6-pyrazin-2-yl-2,7-naphthyridin-1-amine;N-[[3-methyl-4-(2-methyl-4-pyridinyl)phenyl]methyl]-2-(2-methyl-4-pyridinyl)pyrido[3,4-b]pyrazin-5-amine;2-(2-methyl-4-pyridinyl)-N-[[6-(2-methyl-4-pyridinyl)-3-pyridinyl]methyl]pyrido[3,4-b]pyrazin-5-amine
• PubChem CID: 157239491
• Molecular Formula: C104H88FN25
• Molecular Weight: 1707.02 g/mol
• Exact Mass: 1705.76
• IUPAC Name: N-[[3-fluoro-4-(2-methyl-4-pyridinyl)phenyl]methyl]-2-(2-methyl-4-pyridinyl)pyrido[3,4-b]pyrazin-5-amine;N-[[5-methyl-6-(3-methylphenyl)-3-pyridinyl]methyl]-6-pyrazin-2-yl-2,7-naphthyridin-1-amine;N-[[3-methyl-4-(2-methyl-4-pyridinyl)phenyl]methyl]-2-(2-methyl-4-pyridinyl)pyrido[3,4-b]pyrazin-5-amine;2-(2-methyl-4-pyridinyl)-N-[[6-(2-methyl-4-pyridinyl)-3-pyridinyl]methyl]pyrido[3,4-b]pyrazin-5-amine
• SMILES: Cc1cc(-c2ccc(CNc3nccc4nc(-c5ccnc(C)c5)cnc34)cn2)ccn1.Cc1cc(-c2cnc3c(NCc4ccc(-c5ccnc(C)c5)c(C)c4)nccc3n2)ccn1.Cc1cc(-c2cnc3c(NCc4ccc(-c5ccnc(C)c5)c(F)c4)nccc3n2)ccn1.Cc1cccc(-c2ncc(CNc3nccc4cc(-c5cnccn5)ncc34)cc2C)c1
• InChI: InChI=1S/C27H24N6.C26H21FN6.C26H22N6.C25H21N7/c1-17-12-20(4-5-23(17)21-6-9-28-18(2)13-21)15-32-27-26-24(8-11-30-27)33-25(16-31-26)22-7-10-29-19(3)14-22;1-16-11-19(5-8-28-16)21-4-3-18(13-22(21)27)14-32-26-25-23(7-10-30-26)33-24(15-31-25)20-6-9-29-17(2)12-20;1-17-4-3-5-21(10-17)25-18(2)11-19(13-31-25)14-32-26-22-15-30-23(12-20(22)6-7-29-26)24-16-27-8-9-28-24;1-16-11-19(5-8-26-16)21-4-3-18(13-29-21)14-31-25-24-22(7-10-28-25)32-23(15-30-24)20-6-9-27-17(2)12-20/h4-14,16H,15H2,1-3H3,(H,30,32);3-13,15H,14H2,1-2H3,(H,30,32);3-13,15-16H,14H2,1-2H3,(H,29,32);3-13,15H,14H2,1-2H3,(H,28,31)
• InChIKey: AVAPAXNCQCBBAN-UHFFFAOYSA-N
• XLogP: 21.35
• TPSA: 318.81 Ų
• H-Bond Donors: 4
• H-Bond Acceptors: 25
• Rotatable Bonds: 20
• Heavy Atoms: 130
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	1707.02
LogP ≤ 5	21.35
H-Bond Donors ≤ 5	4
H-Bond Acceptors ≤ 10	25

Frequently Asked Questions

What is the IUPAC name of N-[[3-fluoro-4-(2-methyl-4-pyridinyl)phenyl]methyl]-2-(2-methyl-4-pyridinyl)pyrido[3,4-b]pyrazin-5-amine;N-[[5-methyl-6-(3-methylphenyl)-3-pyridinyl]methyl]-6-pyrazin-2-yl-2,7-naphthyridin-1-amine;N-[[3-methyl-4-(2-methyl-4-pyridinyl)phenyl]methyl]-2-(2-methyl-4-pyridinyl)pyrido[3,4-b]pyrazin-5-amine;2-(2-methyl-4-pyridinyl)-N-[[6-(2-methyl-4-pyridinyl)-3-pyridinyl]methyl]pyrido[3,4-b]pyrazin-5-amine?

The IUPAC name of N-[[3-fluoro-4-(2-methyl-4-pyridinyl)phenyl]methyl]-2-(2-methyl-4-pyridinyl)pyrido[3,4-b]pyrazin-5-amine;N-[[5-methyl-6-(3-methylphenyl)-3-pyridinyl]methyl]-6-pyrazin-2-yl-2,7-naphthyridin-1-amine;N-[[3-methyl-4-(2-methyl-4-pyridinyl)phenyl]methyl]-2-(2-methyl-4-pyridinyl)pyrido[3,4-b]pyrazin-5-amine;2-(2-methyl-4-pyridinyl)-N-[[6-(2-methyl-4-pyridinyl)-3-pyridinyl]methyl]pyrido[3,4-b]pyrazin-5-amine (CID 157239491) is N-[[3-fluoro-4-(2-methyl-4-pyridinyl)phenyl]methyl]-2-(2-methyl-4-pyridinyl)pyrido[3,4-b]pyrazin-5-amine;N-[[5-methyl-6-(3-methylphenyl)-3-pyridinyl]methyl]-6-pyrazin-2-yl-2,7-naphthyridin-1-amine;N-[[3-methyl-4-(2-methyl-4-pyridinyl)phenyl]methyl]-2-(2-methyl-4-pyridinyl)pyrido[3,4-b]pyrazin-5-amine;2-(2-methyl-4-pyridinyl)-N-[[6-(2-methyl-4-pyridinyl)-3-pyridinyl]methyl]pyrido[3,4-b]pyrazin-5-amine.

What is the SMILES notation for N-[[3-fluoro-4-(2-methyl-4-pyridinyl)phenyl]methyl]-2-(2-methyl-4-pyridinyl)pyrido[3,4-b]pyrazin-5-amine;N-[[5-methyl-6-(3-methylphenyl)-3-pyridinyl]methyl]-6-pyrazin-2-yl-2,7-naphthyridin-1-amine;N-[[3-methyl-4-(2-methyl-4-pyridinyl)phenyl]methyl]-2-(2-methyl-4-pyridinyl)pyrido[3,4-b]pyrazin-5-amine;2-(2-methyl-4-pyridinyl)-N-[[6-(2-methyl-4-pyridinyl)-3-pyridinyl]methyl]pyrido[3,4-b]pyrazin-5-amine?

The canonical SMILES for N-[[3-fluoro-4-(2-methyl-4-pyridinyl)phenyl]methyl]-2-(2-methyl-4-pyridinyl)pyrido[3,4-b]pyrazin-5-amine;N-[[5-methyl-6-(3-methylphenyl)-3-pyridinyl]methyl]-6-pyrazin-2-yl-2,7-naphthyridin-1-amine;N-[[3-methyl-4-(2-methyl-4-pyridinyl)phenyl]methyl]-2-(2-methyl-4-pyridinyl)pyrido[3,4-b]pyrazin-5-amine;2-(2-methyl-4-pyridinyl)-N-[[6-(2-methyl-4-pyridinyl)-3-pyridinyl]methyl]pyrido[3,4-b]pyrazin-5-amine is Cc1cc(-c2ccc(CNc3nccc4nc(-c5ccnc(C)c5)cnc34)cn2)ccn1.Cc1cc(-c2cnc3c(NCc4ccc(-c5ccnc(C)c5)c(C)c4)nccc3n2)ccn1.Cc1cc(-c2cnc3c(NCc4ccc(-c5ccnc(C)c5)c(F)c4)nccc3n2)ccn1.Cc1cccc(-c2ncc(CNc3nccc4cc(-c5cnccn5)ncc34)cc2C)c1.

What is the InChIKey of N-[[3-fluoro-4-(2-methyl-4-pyridinyl)phenyl]methyl]-2-(2-methyl-4-pyridinyl)pyrido[3,4-b]pyrazin-5-amine;N-[[5-methyl-6-(3-methylphenyl)-3-pyridinyl]methyl]-6-pyrazin-2-yl-2,7-naphthyridin-1-amine;N-[[3-methyl-4-(2-methyl-4-pyridinyl)phenyl]methyl]-2-(2-methyl-4-pyridinyl)pyrido[3,4-b]pyrazin-5-amine;2-(2-methyl-4-pyridinyl)-N-[[6-(2-methyl-4-pyridinyl)-3-pyridinyl]methyl]pyrido[3,4-b]pyrazin-5-amine?

The InChIKey is AVAPAXNCQCBBAN-UHFFFAOYSA-N. The full InChI is InChI=1S/C27H24N6.C26H21FN6.C26H22N6.C25H21N7/c1-17-12-20(4-5-23(17)21-6-9-28-18(2)13-21)15-32-27-26-24(8-11-30-27)33-25(16-31-26)22-7-10-29-19(3)14-22;1-16-11-19(5-8-28-16)21-4-3-18(13-22(21)27)14-32-26-25-23(7-10-30-26)33-24(15-31-25)20-6-9-29-17(2)12-20;1-17-4-3-5-21(10-17)25-18(2)11-19(13-31-25)14-32-26-22-15-30-23(12-20(22)6-7-29-26)24-16-27-8-9-28-24;1-16-11-19(5-8-26-16)21-4-3-18(13-29-21)14-31-25-24-22(7-10-28-25)32-23(15-30-24)20-6-9-27-17(2)12-20/h4-14,16H,15H2,1-3H3,(H,30,32);3-13,15H,14H2,1-2H3,(H,30,32);3-13,15-16H,14H2,1-2H3,(H,29,32);3-13,15H,14H2,1-2H3,(H,28,31).

What are the key properties of N-[[3-fluoro-4-(2-methyl-4-pyridinyl)phenyl]methyl]-2-(2-methyl-4-pyridinyl)pyrido[3,4-b]pyrazin-5-amine;N-[[5-methyl-6-(3-methylphenyl)-3-pyridinyl]methyl]-6-pyrazin-2-yl-2,7-naphthyridin-1-amine;N-[[3-methyl-4-(2-methyl-4-pyridinyl)phenyl]methyl]-2-(2-methyl-4-pyridinyl)pyrido[3,4-b]pyrazin-5-amine;2-(2-methyl-4-pyridinyl)-N-[[6-(2-methyl-4-pyridinyl)-3-pyridinyl]methyl]pyrido[3,4-b]pyrazin-5-amine?

N-[[3-fluoro-4-(2-methyl-4-pyridinyl)phenyl]methyl]-2-(2-methyl-4-pyridinyl)pyrido[3,4-b]pyrazin-5-amine;N-[[5-methyl-6-(3-methylphenyl)-3-pyridinyl]methyl]-6-pyrazin-2-yl-2,7-naphthyridin-1-amine;N-[[3-methyl-4-(2-methyl-4-pyridinyl)phenyl]methyl]-2-(2-methyl-4-pyridinyl)pyrido[3,4-b]pyrazin-5-amine;2-(2-methyl-4-pyridinyl)-N-[[6-(2-methyl-4-pyridinyl)-3-pyridinyl]methyl]pyrido[3,4-b]pyrazin-5-amine has a molecular weight of 1707.02 g/mol, XLogP of 21.35, 20 rotatable bonds, 4 hydrogen bond donors, and 25 hydrogen bond acceptors.

Where does this data come from?

All data for N-[[3-fluoro-4-(2-methyl-4-pyridinyl)phenyl]methyl]-2-(2-methyl-4-pyridinyl)pyrido[3,4-b]pyrazin-5-amine;N-[[5-methyl-6-(3-methylphenyl)-3-pyridinyl]methyl]-6-pyrazin-2-yl-2,7-naphthyridin-1-amine;N-[[3-methyl-4-(2-methyl-4-pyridinyl)phenyl]methyl]-2-(2-methyl-4-pyridinyl)pyrido[3,4-b]pyrazin-5-amine;2-(2-methyl-4-pyridinyl)-N-[[6-(2-methyl-4-pyridinyl)-3-pyridinyl]methyl]pyrido[3,4-b]pyrazin-5-amine is sourced from PubChem (CID 157239491), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).