N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-3,3-difluoro-2,2-dimethylbutanamide;N-[5-chloro-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;N-[5-chloro-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-5,5-dimethylhexanamide;N-(3-cyclobutyl-7-methylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;N-(3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-2-(4-methylphenyl)acetamide;N-(3-cyclobutyl-7-methylimidazo[4,5-b]pyridin-2-yl)-3-[(2-methylpropan-2-yl)oxy]propanamide

C101H127Cl3F8N24O7 — CID 157239805

About N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-3,3-difluoro-2,2-dimethylbutanamide;N-[5-chloro-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;N-[5-chloro-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-5,5-dimethylhexanamide;N-(3-cyclobutyl-7-methylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;N-(3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-2-(4-methylphenyl)acetamide;N-(3-cyclobutyl-7-methylimidazo[4,5-b]pyridin-2-yl)-3-[(2-methylpropan-2-yl)oxy]propanamide

N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-3,3-difluoro-2,2-dimethylbutanamide;N-[5-chloro-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;N-[5-chloro-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-5,5-dimethylhexanamide;N-(3-cyclobutyl-7-methylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;N-(3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-2-(4-methylphenyl)acetamide;N-(3-cyclobutyl-7-methylimidazo[4,5-b]pyridin-2-yl)-3-[(2-methylpropan-2-yl)oxy]propanamide (PubChem CID 157239805) has the molecular formula C101H127Cl3F8N24O7 and a molecular weight of 2047.63 g/mol. Its IUPAC name is N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-3,3-difluoro-2,2-dimethylbutanamide;N-[5-chloro-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;N-[5-chloro-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-5,5-dimethylhexanamide;N-(3-cyclobutyl-7-methylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;N-(3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-2-(4-methylphenyl)acetamide;N-(3-cyclobutyl-7-methylimidazo[4,5-b]pyridin-2-yl)-3-[(2-methylpropan-2-yl)oxy]propanamide.

Molecular Properties

• Compound Name: N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-3,3-difluoro-2,2-dimethylbutanamide;N-[5-chloro-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;N-[5-chloro-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-5,5-dimethylhexanamide;N-(3-cyclobutyl-7-methylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;N-(3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-2-(4-methylphenyl)acetamide;N-(3-cyclobutyl-7-methylimidazo[4,5-b]pyridin-2-yl)-3-[(2-methylpropan-2-yl)oxy]propanamide
• PubChem CID: 157239805
• Molecular Formula: C101H127Cl3F8N24O7
• Molecular Weight: 2047.63 g/mol
• Exact Mass: 2044.93
• IUPAC Name: N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-3,3-difluoro-2,2-dimethylbutanamide;N-[5-chloro-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;N-[5-chloro-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-5,5-dimethylhexanamide;N-(3-cyclobutyl-7-methylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;N-(3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-2-(4-methylphenyl)acetamide;N-(3-cyclobutyl-7-methylimidazo[4,5-b]pyridin-2-yl)-3-[(2-methylpropan-2-yl)oxy]propanamide
• SMILES: CC(C)(C)CC(=O)Nc1nc2ccc(Cl)nc2n1CC(F)(F)F.CC(C)(C)CCCC(=O)Nc1nc2ccc(Cl)nc2n1CC(F)(F)F.CC(F)(F)C(C)(C)C(=O)Nc1nc2ccc(Cl)nc2n1C1CCC1.Cc1ccc(CC(=O)Nc2nc3cc(C)cnc3n2C2CCC2)cc1.Cc1ccnc2c1nc(NC(=O)CC(C)(C)C)n2C1CCC1.Cc1ccnc2c1nc(NC(=O)CCOC(C)(C)C)n2C1CCC1
• InChI: InChI=1S/C20H22N4O.C18H26N4O2.C17H24N4O.C16H20ClF3N4O.C16H19ClF2N4O.C14H16ClF3N4O/c1-13-6-8-15(9-7-13)11-18(25)23-20-22-17-10-14(2)12-21-19(17)24(20)16-4-3-5-16;1-12-8-10-19-16-15(12)21-17(22(16)13-6-5-7-13)20-14(23)9-11-24-18(2,3)4;1-11-8-9-18-15-14(11)20-16(21(15)12-6-5-7-12)19-13(22)10-17(2,3)4;1-15(2,3)8-4-5-12(25)23-14-21-10-6-7-11(17)22-13(10)24(14)9-16(18,19)20;1-15(2,16(3,18)19)13(24)22-14-20-10-7-8-11(17)21-12(10)23(14)9-5-4-6-9;1-13(2,3)6-10(23)21-12-19-8-4-5-9(15)20-11(8)22(12)7-14(16,17)18/h6-10,12,16H,3-5,11H2,1-2H3,(H,22,23,25);8,10,13H,5-7,9,11H2,1-4H3,(H,20,21,23);8-9,12H,5-7,10H2,1-4H3,(H,19,20,22);6-7H,4-5,8-9H2,1-3H3,(H,21,23,25);7-9H,4-6H2,1-3H3,(H,20,22,24);4-5H,6-7H2,1-3H3,(H,19,21,23)
• InChIKey: AVBOHJQYTPKIRB-UHFFFAOYSA-N
• XLogP: 24.66
• TPSA: 368.09 Ų
• H-Bond Donors: 6
• H-Bond Acceptors: 25
• Rotatable Bonds: 24
• Heavy Atoms: 143
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2047.63
LogP ≤ 5	24.66
H-Bond Donors ≤ 5	6
H-Bond Acceptors ≤ 10	25

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': '2-halo_pyridine', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-3,3-difluoro-2,2-dimethylbutanamide;N-[5-chloro-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;N-[5-chloro-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-5,5-dimethylhexanamide;N-(3-cyclobutyl-7-methylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;N-(3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-2-(4-methylphenyl)acetamide;N-(3-cyclobutyl-7-methylimidazo[4,5-b]pyridin-2-yl)-3-[(2-methylpropan-2-yl)oxy]propanamide?

The IUPAC name of N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-3,3-difluoro-2,2-dimethylbutanamide;N-[5-chloro-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;N-[5-chloro-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-5,5-dimethylhexanamide;N-(3-cyclobutyl-7-methylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;N-(3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-2-(4-methylphenyl)acetamide;N-(3-cyclobutyl-7-methylimidazo[4,5-b]pyridin-2-yl)-3-[(2-methylpropan-2-yl)oxy]propanamide (CID 157239805) is N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-3,3-difluoro-2,2-dimethylbutanamide;N-[5-chloro-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;N-[5-chloro-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-5,5-dimethylhexanamide;N-(3-cyclobutyl-7-methylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;N-(3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-2-(4-methylphenyl)acetamide;N-(3-cyclobutyl-7-methylimidazo[4,5-b]pyridin-2-yl)-3-[(2-methylpropan-2-yl)oxy]propanamide.

What is the SMILES notation for N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-3,3-difluoro-2,2-dimethylbutanamide;N-[5-chloro-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;N-[5-chloro-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-5,5-dimethylhexanamide;N-(3-cyclobutyl-7-methylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;N-(3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-2-(4-methylphenyl)acetamide;N-(3-cyclobutyl-7-methylimidazo[4,5-b]pyridin-2-yl)-3-[(2-methylpropan-2-yl)oxy]propanamide?

The canonical SMILES for N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-3,3-difluoro-2,2-dimethylbutanamide;N-[5-chloro-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;N-[5-chloro-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-5,5-dimethylhexanamide;N-(3-cyclobutyl-7-methylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;N-(3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-2-(4-methylphenyl)acetamide;N-(3-cyclobutyl-7-methylimidazo[4,5-b]pyridin-2-yl)-3-[(2-methylpropan-2-yl)oxy]propanamide is CC(C)(C)CC(=O)Nc1nc2ccc(Cl)nc2n1CC(F)(F)F.CC(C)(C)CCCC(=O)Nc1nc2ccc(Cl)nc2n1CC(F)(F)F.CC(F)(F)C(C)(C)C(=O)Nc1nc2ccc(Cl)nc2n1C1CCC1.Cc1ccc(CC(=O)Nc2nc3cc(C)cnc3n2C2CCC2)cc1.Cc1ccnc2c1nc(NC(=O)CC(C)(C)C)n2C1CCC1.Cc1ccnc2c1nc(NC(=O)CCOC(C)(C)C)n2C1CCC1.

What is the InChIKey of N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-3,3-difluoro-2,2-dimethylbutanamide;N-[5-chloro-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;N-[5-chloro-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-5,5-dimethylhexanamide;N-(3-cyclobutyl-7-methylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;N-(3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-2-(4-methylphenyl)acetamide;N-(3-cyclobutyl-7-methylimidazo[4,5-b]pyridin-2-yl)-3-[(2-methylpropan-2-yl)oxy]propanamide?

The InChIKey is AVBOHJQYTPKIRB-UHFFFAOYSA-N. The full InChI is InChI=1S/C20H22N4O.C18H26N4O2.C17H24N4O.C16H20ClF3N4O.C16H19ClF2N4O.C14H16ClF3N4O/c1-13-6-8-15(9-7-13)11-18(25)23-20-22-17-10-14(2)12-21-19(17)24(20)16-4-3-5-16;1-12-8-10-19-16-15(12)21-17(22(16)13-6-5-7-13)20-14(23)9-11-24-18(2,3)4;1-11-8-9-18-15-14(11)20-16(21(15)12-6-5-7-12)19-13(22)10-17(2,3)4;1-15(2,3)8-4-5-12(25)23-14-21-10-6-7-11(17)22-13(10)24(14)9-16(18,19)20;1-15(2,16(3,18)19)13(24)22-14-20-10-7-8-11(17)21-12(10)23(14)9-5-4-6-9;1-13(2,3)6-10(23)21-12-19-8-4-5-9(15)20-11(8)22(12)7-14(16,17)18/h6-10,12,16H,3-5,11H2,1-2H3,(H,22,23,25);8,10,13H,5-7,9,11H2,1-4H3,(H,20,21,23);8-9,12H,5-7,10H2,1-4H3,(H,19,20,22);6-7H,4-5,8-9H2,1-3H3,(H,21,23,25);7-9H,4-6H2,1-3H3,(H,20,22,24);4-5H,6-7H2,1-3H3,(H,19,21,23).

What are the key properties of N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-3,3-difluoro-2,2-dimethylbutanamide;N-[5-chloro-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;N-[5-chloro-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-5,5-dimethylhexanamide;N-(3-cyclobutyl-7-methylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;N-(3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-2-(4-methylphenyl)acetamide;N-(3-cyclobutyl-7-methylimidazo[4,5-b]pyridin-2-yl)-3-[(2-methylpropan-2-yl)oxy]propanamide?

N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-3,3-difluoro-2,2-dimethylbutanamide;N-[5-chloro-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;N-[5-chloro-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-5,5-dimethylhexanamide;N-(3-cyclobutyl-7-methylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;N-(3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-2-(4-methylphenyl)acetamide;N-(3-cyclobutyl-7-methylimidazo[4,5-b]pyridin-2-yl)-3-[(2-methylpropan-2-yl)oxy]propanamide has a molecular weight of 2047.63 g/mol, XLogP of 24.66, 24 rotatable bonds, 6 hydrogen bond donors, and 25 hydrogen bond acceptors.

Where does this data come from?

All data for N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-3,3-difluoro-2,2-dimethylbutanamide;N-[5-chloro-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;N-[5-chloro-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-5,5-dimethylhexanamide;N-(3-cyclobutyl-7-methylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;N-(3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-2-(4-methylphenyl)acetamide;N-(3-cyclobutyl-7-methylimidazo[4,5-b]pyridin-2-yl)-3-[(2-methylpropan-2-yl)oxy]propanamide is sourced from PubChem (CID 157239805), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).