1-[4-(2-aminopyrimidin-5-yl)phenyl]-N-(3-chloro-4-morpholin-4-ylphenyl)cyclobutane-1-carboxamide;1-[4-(2-aminopyrimidin-5-yl)phenyl]-N-(4-cyanophenyl)cyclobutane-1-carboxamide;1-[4-(2-aminopyrimidin-5-yl)phenyl]-N-[2-(4-methylpiperazin-1-yl)-4-pyridinyl]cyclobutane-1-carboxamide;2-[4-(2,3-dihydro-1H-pyrrolo[2,3-b]pyridin-5-yl)phenyl]-N-[5-(5-methoxy-3-pyridinyl)-2-pyridinyl]-2,3-dimethylbutanamide;N-[5-(6-methoxy-3-pyridinyl)-2-pyridinyl]-2,3-dimethyl-2-[4-(1H-pyrrolo[2,3-b]pyridin-5-yl)phenyl]butanamide

C132H134ClN27O8 — CID 157239835

IUPAC1-[4-(2-aminopyrimidin-5-yl)phenyl]-N-(3-chloro-4-morpholin-4-ylphenyl)cyclobutane-1-carboxamide;1-[4-(2-aminopyrimidin-5-yl)phenyl]-N-(4-cyanophenyl)cyclobutane-1-carboxamide;1-[4-(2-aminopyrimidin-5-yl)phenyl]-N-[2-(4-methylpiperazin-1-yl)-4-pyridinyl]cyclobutane-1-carboxamide;2-[4-(2,3-dihydro-1H-pyrrolo[2,3-b]pyridin-5-yl)phenyl]-N-[5-(5-methoxy-3-pyridinyl)-2-pyridinyl]-2,3-dimethylbutanamide;N-[5-(6-methoxy-3-pyridinyl)-2-pyridinyl]-2,3-dimethyl-2-[4-(1H-pyrrolo[2,3-b]pyridin-5-yl)phenyl]butanamide
SMILESCN1CCN(c2cc(NC(=O)C3(c4ccc(-c5cnc(N)nc5)cc4)CCC3)ccn2)CC1.COc1ccc(-c2ccc(NC(=O)C(C)(c3ccc(-c4cnc5[nH]ccc5c4)cc3)C(C)C)nc2)cn1.COc1cncc(-c2ccc(NC(=O)C(C)(c3ccc(-c4cnc5c(c4)CCN5)cc3)C(C)C)nc2)c1.N#Cc1ccc(NC(=O)C2(c3ccc(-c4cnc(N)nc4)cc3)CCC2)cc1.Nc1ncc(-c2ccc(C3(C(=O)Nc4ccc(N5CCOCC5)c(Cl)c4)CCC3)cc2)cn1
InChIInChI=1S/C30H29N5O2.C30H31N5O2.C25H26ClN5O2.C25H29N7O.C22H19N5O/c1-19(2)30(3,25-9-5-20(6-10-25)24-15-21-13-14-31-28(21)34-18-24)29(36)35-26-11-7-22(16-32-26)23-8-12-27(37-4)33-17-23;1-19(2)30(3,25-8-5-20(6-9-25)23-13-21-11-12-32-28(21)34-17-23)29(36)35-27-10-7-22(16-33-27)24-14-26(37-4)18-31-15-24;26-21-14-20(6-7-22(21)31-10-12-33-13-11-31)30-23(32)25(8-1-9-25)19-4-2-17(3-5-19)18-15-28-24(27)29-16-18;1-31-11-13-32(14-12-31)22-15-21(7-10-27-22)30-23(33)25(8-2-9-25)20-5-3-18(4-6-20)19-16-28-24(26)29-17-19;23-12-15-2-8-19(9-3-15)27-20(28)22(10-1-11-22)18-6-4-16(5-7-18)17-13-25-21(24)26-14-17/h5-19H,1-4H3,(H,31,34)(H,32,35,36);5-10,13-19H,11-12H2,1-4H3,(H,32,34)(H,33,35,36);2-7,14-16H,1,8-13H2,(H,30,32)(H2,27,28,29);3-7,10,15-17H,2,8-9,11-14H2,1H3,(H2,26,28,29)(H,27,30,33);2-9,13-14H,1,10-11H2,(H,27,28)(H2,24,25,26)
InChIKeyAVBQTACALWMICP-UHFFFAOYSA-N
MW2262.16 g/mol
LogP22.85
Rot. Bonds28

About 1-[4-(2-aminopyrimidin-5-yl)phenyl]-N-(3-chloro-4-morpholin-4-ylphenyl)cyclobutane-1-carboxamide;1-[4-(2-aminopyrimidin-5-yl)phenyl]-N-(4-cyanophenyl)cyclobutane-1-carboxamide;1-[4-(2-aminopyrimidin-5-yl)phenyl]-N-[2-(4-methylpiperazin-1-yl)-4-pyridinyl]cyclobutane-1-carboxamide;2-[4-(2,3-dihydro-1H-pyrrolo[2,3-b]pyridin-5-yl)phenyl]-N-[5-(5-methoxy-3-pyridinyl)-2-pyridinyl]-2,3-dimethylbutanamide;N-[5-(6-methoxy-3-pyridinyl)-2-pyridinyl]-2,3-dimethyl-2-[4-(1H-pyrrolo[2,3-b]pyridin-5-yl)phenyl]butanamide

1-[4-(2-aminopyrimidin-5-yl)phenyl]-N-(3-chloro-4-morpholin-4-ylphenyl)cyclobutane-1-carboxamide;1-[4-(2-aminopyrimidin-5-yl)phenyl]-N-(4-cyanophenyl)cyclobutane-1-carboxamide;1-[4-(2-aminopyrimidin-5-yl)phenyl]-N-[2-(4-methylpiperazin-1-yl)-4-pyridinyl]cyclobutane-1-carboxamide;2-[4-(2,3-dihydro-1H-pyrrolo[2,3-b]pyridin-5-yl)phenyl]-N-[5-(5-methoxy-3-pyridinyl)-2-pyridinyl]-2,3-dimethylbutanamide;N-[5-(6-methoxy-3-pyridinyl)-2-pyridinyl]-2,3-dimethyl-2-[4-(1H-pyrrolo[2,3-b]pyridin-5-yl)phenyl]butanamide (PubChem CID 157239835) has the molecular formula C132H134ClN27O8 and a molecular weight of 2262.16 g/mol. Its IUPAC name is 1-[4-(2-aminopyrimidin-5-yl)phenyl]-N-(3-chloro-4-morpholin-4-ylphenyl)cyclobutane-1-carboxamide;1-[4-(2-aminopyrimidin-5-yl)phenyl]-N-(4-cyanophenyl)cyclobutane-1-carboxamide;1-[4-(2-aminopyrimidin-5-yl)phenyl]-N-[2-(4-methylpiperazin-1-yl)-4-pyridinyl]cyclobutane-1-carboxamide;2-[4-(2,3-dihydro-1H-pyrrolo[2,3-b]pyridin-5-yl)phenyl]-N-[5-(5-methoxy-3-pyridinyl)-2-pyridinyl]-2,3-dimethylbutanamide;N-[5-(6-methoxy-3-pyridinyl)-2-pyridinyl]-2,3-dimethyl-2-[4-(1H-pyrrolo[2,3-b]pyridin-5-yl)phenyl]butanamide.

Molecular Properties

Compound Name1-[4-(2-aminopyrimidin-5-yl)phenyl]-N-(3-chloro-4-morpholin-4-ylphenyl)cyclobutane-1-carboxamide;1-[4-(2-aminopyrimidin-5-yl)phenyl]-N-(4-cyanophenyl)cyclobutane-1-carboxamide;1-[4-(2-aminopyrimidin-5-yl)phenyl]-N-[2-(4-methylpiperazin-1-yl)-4-pyridinyl]cyclobutane-1-carboxamide;2-[4-(2,3-dihydro-1H-pyrrolo[2,3-b]pyridin-5-yl)phenyl]-N-[5-(5-methoxy-3-pyridinyl)-2-pyridinyl]-2,3-dimethylbutanamide;N-[5-(6-methoxy-3-pyridinyl)-2-pyridinyl]-2,3-dimethyl-2-[4-(1H-pyrrolo[2,3-b]pyridin-5-yl)phenyl]butanamide
PubChem CID157239835
Molecular FormulaC132H134ClN27O8
Molecular Weight2262.16 g/mol
Exact Mass2260.06
IUPAC Name1-[4-(2-aminopyrimidin-5-yl)phenyl]-N-(3-chloro-4-morpholin-4-ylphenyl)cyclobutane-1-carboxamide;1-[4-(2-aminopyrimidin-5-yl)phenyl]-N-(4-cyanophenyl)cyclobutane-1-carboxamide;1-[4-(2-aminopyrimidin-5-yl)phenyl]-N-[2-(4-methylpiperazin-1-yl)-4-pyridinyl]cyclobutane-1-carboxamide;2-[4-(2,3-dihydro-1H-pyrrolo[2,3-b]pyridin-5-yl)phenyl]-N-[5-(5-methoxy-3-pyridinyl)-2-pyridinyl]-2,3-dimethylbutanamide;N-[5-(6-methoxy-3-pyridinyl)-2-pyridinyl]-2,3-dimethyl-2-[4-(1H-pyrrolo[2,3-b]pyridin-5-yl)phenyl]butanamide
SMILESCN1CCN(c2cc(NC(=O)C3(c4ccc(-c5cnc(N)nc5)cc4)CCC3)ccn2)CC1.COc1ccc(-c2ccc(NC(=O)C(C)(c3ccc(-c4cnc5[nH]ccc5c4)cc3)C(C)C)nc2)cn1.COc1cncc(-c2ccc(NC(=O)C(C)(c3ccc(-c4cnc5c(c4)CCN5)cc3)C(C)C)nc2)c1.N#Cc1ccc(NC(=O)C2(c3ccc(-c4cnc(N)nc4)cc3)CCC2)cc1.Nc1ncc(-c2ccc(C3(C(=O)Nc4ccc(N5CCOCC5)c(Cl)c4)CCC3)cc2)cn1
InChIInChI=1S/C30H29N5O2.C30H31N5O2.C25H26ClN5O2.C25H29N7O.C22H19N5O/c1-19(2)30(3,25-9-5-20(6-10-25)24-15-21-13-14-31-28(21)34-18-24)29(36)35-26-11-7-22(16-32-26)23-8-12-27(37-4)33-17-23;1-19(2)30(3,25-8-5-20(6-9-25)23-13-21-11-12-32-28(21)34-17-23)29(36)35-27-10-7-22(16-33-27)24-14-26(37-4)18-31-15-24;26-21-14-20(6-7-22(21)31-10-12-33-13-11-31)30-23(32)25(8-1-9-25)19-4-2-17(3-5-19)18-15-28-24(27)29-16-18;1-31-11-13-32(14-12-31)22-15-21(7-10-27-22)30-23(33)25(8-2-9-25)20-5-3-18(4-6-20)19-16-28-24(26)29-17-19;23-12-15-2-8-19(9-3-15)27-20(28)22(10-1-11-22)18-6-4-16(5-7-18)17-13-25-21(24)26-14-17/h5-19H,1-4H3,(H,31,34)(H,32,35,36);5-10,13-19H,11-12H2,1-4H3,(H,32,34)(H,33,35,36);2-7,14-16H,1,8-13H2,(H,30,32)(H2,27,28,29);3-7,10,15-17H,2,8-9,11-14H2,1H3,(H2,26,28,29)(H,27,30,33);2-9,13-14H,1,10-11H2,(H,27,28)(H2,24,25,26)
InChIKeyAVBQTACALWMICP-UHFFFAOYSA-N
XLogP22.85
TPSA480.15 Ų
H-Bond Donors10
H-Bond Acceptors29
Rotatable Bonds28
Heavy Atoms168
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5002262.16
LogP ≤ 522.85
H-Bond Donors ≤ 510
H-Bond Acceptors ≤ 1029

Computed Properties (RDKit)

Structural Alerts{'alert_name': 'anil_di_alk_A(478)', 'substructure': 'N/A'}

Analyze 1-[4-(2-aminopyrimidin-5-yl)phenyl]-N-(3-chloro-4-morpholin-4-ylphenyl)cyclobutane-1-carboxamide;1-[4-(2-aminopyrimidin-5-yl)phenyl]-N-(4-cyanophenyl)cyclobutane-1-carboxamide;1-[4-(2-aminopyrimidin-5-yl)phenyl]-N-[2-(4-methylpiperazin-1-yl)-4-pyridinyl]cyclobutane-1-carboxamide;2-[4-(2,3-dihydro-1H-pyrrolo[2,3-b]pyridin-5-yl)phenyl]-N-[5-(5-methoxy-3-pyridinyl)-2-pyridinyl]-2,3-dimethylbutanamide;N-[5-(6-methoxy-3-pyridinyl)-2-pyridinyl]-2,3-dimethyl-2-[4-(1H-pyrrolo[2,3-b]pyridin-5-yl)phenyl]butanamide with MolForge

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Related Compounds

4-[4-(2-aminopyrimidin-5-yl)phenyl]-N-[4-cyano-3-(trifluoromethyl)phenyl]oxane-4-carboxamide;2-[4-(2-aminopyrimidin-5-yl)phenyl]-2,3-dimethyl-N-pyridin-4-ylbutanamide;4-[4-(2-aminopyrimidin-5-yl)phenyl]-N-[4-(trifluoromethyl)phenyl]oxane-4-carboxamide;N-[5-(5-ethyl-3-pyridinyl)-2-pyridinyl]-4-[4-(1H-pyrrolo[2,3-b]pyridin-5-yl)phenyl]oxane-4-carboxamide;N-[5-(6-methoxy-3-pyridinyl)-2-pyridinyl]-4-[4-(1H-pyrrolo[2,3-b]pyridin-5-yl)phenyl]oxane-4-carboxamide
CID 157283667
4-[4-(2-aminopyrimidin-5-yl)phenyl]-N-[5-(2-hydroxypropan-2-yl)-2-pyridinyl]oxane-4-carboxamide;6-[2-[4-[4-(2-aminopyrimidin-5-yl)phenyl]oxan-4-yl]-2-oxoethyl]pyridine-3-carbonitrile;1-[4-(2-aminopyrimidin-5-yl)phenyl]-N-pyridin-2-ylcyclohexane-1-carboxamide;N-[5-(5-methoxy-3-pyridinyl)-2-pyridinyl]-4-[4-(1H-pyrrolo[2,3-b]pyridin-5-yl)phenyl]oxane-4-carboxamide;N-[5-(6-methoxy-3-pyridinyl)-2-pyridinyl]-4-[4-(1H-pyrrolo[2,3-b]pyridin-5-yl)phenyl]oxane-4-carboxamide
CID 157650228
1-[4-(2-aminopyrimidin-5-yl)phenyl]-N-(3-chloro-4-cyanophenyl)cyclobutane-1-carboxamide;4-[4-(2-aminopyrimidin-5-yl)phenyl]-N-(4-chloro-3-fluorophenyl)oxane-4-carboxamide;1-[4-(2-aminopyrimidin-5-yl)phenyl]-N-(3-methyl-4-pyridinyl)cyclobutane-1-carboxamide;1-[4-(2-aminopyrimidin-5-yl)phenyl]-N-(5-phenoxy-2-pyridinyl)cyclobutane-1-carboxamide;4-[4-(2-aminopyrimidin-5-yl)phenyl]-N-(6-phenyl-3-pyridinyl)oxane-4-carboxamide
CID 158050452
4-[4-[6-amino-5-(hydroxymethyl)-3-pyridinyl]phenyl]-N-(5-cyano-2-pyridinyl)oxane-4-carboxamide;4-[4-(2-aminopyrimidin-5-yl)phenyl]-N-(3-chloro-4-cyanophenyl)oxane-4-carboxamide;1-[4-[4-(2-aminopyrimidin-5-yl)phenyl]oxan-4-yl]-2-[4-(1,3-oxazol-5-yl)phenyl]ethanone;4-[4-(2-aminopyrimidin-5-yl)phenyl]-N-(4-pyridin-4-ylphenyl)oxane-4-carboxamide;2,3-dimethyl-N-pyridin-3-yl-2-[4-(1H-pyrrolo[2,3-b]pyridin-5-yl)phenyl]butanamide
CID 158800522
1-[4-(2-aminopyrimidin-5-yl)phenyl]-N-(3-chloro-4-cyanophenyl)cyclobutane-1-carboxamide;1-[4-(2-aminopyrimidin-5-yl)phenyl]-N-[4-(dimethylsulfamoyl)phenyl]cyclobutane-1-carboxamide;1-[4-(2-aminopyrimidin-5-yl)phenyl]-N-(6-methylsulfonyl-3-pyridinyl)cyclobutane-1-carboxamide;1-[4-(2-aminopyrimidin-5-yl)phenyl]-N-(4-morpholin-4-ylsulfonylphenyl)cyclobutane-1-carboxamide;N-(2-methoxy-4-pyridinyl)-1-[4-(1H-pyrrolo[2,3-b]pyridin-5-yl)phenyl]cyclobutane-1-carboxamide;N-(5-phenoxy-2-pyridinyl)-1-[4-(1H-pyrrolo[2,3-b]pyridin-5-yl)phenyl]cyclobutane-1-carboxamide
CID 161622834

Frequently Asked Questions

What is the IUPAC name of 1-[4-(2-aminopyrimidin-5-yl)phenyl]-N-(3-chloro-4-morpholin-4-ylphenyl)cyclobutane-1-carboxamide;1-[4-(2-aminopyrimidin-5-yl)phenyl]-N-(4-cyanophenyl)cyclobutane-1-carboxamide;1-[4-(2-aminopyrimidin-5-yl)phenyl]-N-[2-(4-methylpiperazin-1-yl)-4-pyridinyl]cyclobutane-1-carboxamide;2-[4-(2,3-dihydro-1H-pyrrolo[2,3-b]pyridin-5-yl)phenyl]-N-[5-(5-methoxy-3-pyridinyl)-2-pyridinyl]-2,3-dimethylbutanamide;N-[5-(6-methoxy-3-pyridinyl)-2-pyridinyl]-2,3-dimethyl-2-[4-(1H-pyrrolo[2,3-b]pyridin-5-yl)phenyl]butanamide?
The IUPAC name of 1-[4-(2-aminopyrimidin-5-yl)phenyl]-N-(3-chloro-4-morpholin-4-ylphenyl)cyclobutane-1-carboxamide;1-[4-(2-aminopyrimidin-5-yl)phenyl]-N-(4-cyanophenyl)cyclobutane-1-carboxamide;1-[4-(2-aminopyrimidin-5-yl)phenyl]-N-[2-(4-methylpiperazin-1-yl)-4-pyridinyl]cyclobutane-1-carboxamide;2-[4-(2,3-dihydro-1H-pyrrolo[2,3-b]pyridin-5-yl)phenyl]-N-[5-(5-methoxy-3-pyridinyl)-2-pyridinyl]-2,3-dimethylbutanamide;N-[5-(6-methoxy-3-pyridinyl)-2-pyridinyl]-2,3-dimethyl-2-[4-(1H-pyrrolo[2,3-b]pyridin-5-yl)phenyl]butanamide (CID 157239835) is 1-[4-(2-aminopyrimidin-5-yl)phenyl]-N-(3-chloro-4-morpholin-4-ylphenyl)cyclobutane-1-carboxamide;1-[4-(2-aminopyrimidin-5-yl)phenyl]-N-(4-cyanophenyl)cyclobutane-1-carboxamide;1-[4-(2-aminopyrimidin-5-yl)phenyl]-N-[2-(4-methylpiperazin-1-yl)-4-pyridinyl]cyclobutane-1-carboxamide;2-[4-(2,3-dihydro-1H-pyrrolo[2,3-b]pyridin-5-yl)phenyl]-N-[5-(5-methoxy-3-pyridinyl)-2-pyridinyl]-2,3-dimethylbutanamide;N-[5-(6-methoxy-3-pyridinyl)-2-pyridinyl]-2,3-dimethyl-2-[4-(1H-pyrrolo[2,3-b]pyridin-5-yl)phenyl]butanamide.
What is the SMILES notation for 1-[4-(2-aminopyrimidin-5-yl)phenyl]-N-(3-chloro-4-morpholin-4-ylphenyl)cyclobutane-1-carboxamide;1-[4-(2-aminopyrimidin-5-yl)phenyl]-N-(4-cyanophenyl)cyclobutane-1-carboxamide;1-[4-(2-aminopyrimidin-5-yl)phenyl]-N-[2-(4-methylpiperazin-1-yl)-4-pyridinyl]cyclobutane-1-carboxamide;2-[4-(2,3-dihydro-1H-pyrrolo[2,3-b]pyridin-5-yl)phenyl]-N-[5-(5-methoxy-3-pyridinyl)-2-pyridinyl]-2,3-dimethylbutanamide;N-[5-(6-methoxy-3-pyridinyl)-2-pyridinyl]-2,3-dimethyl-2-[4-(1H-pyrrolo[2,3-b]pyridin-5-yl)phenyl]butanamide?
The canonical SMILES for 1-[4-(2-aminopyrimidin-5-yl)phenyl]-N-(3-chloro-4-morpholin-4-ylphenyl)cyclobutane-1-carboxamide;1-[4-(2-aminopyrimidin-5-yl)phenyl]-N-(4-cyanophenyl)cyclobutane-1-carboxamide;1-[4-(2-aminopyrimidin-5-yl)phenyl]-N-[2-(4-methylpiperazin-1-yl)-4-pyridinyl]cyclobutane-1-carboxamide;2-[4-(2,3-dihydro-1H-pyrrolo[2,3-b]pyridin-5-yl)phenyl]-N-[5-(5-methoxy-3-pyridinyl)-2-pyridinyl]-2,3-dimethylbutanamide;N-[5-(6-methoxy-3-pyridinyl)-2-pyridinyl]-2,3-dimethyl-2-[4-(1H-pyrrolo[2,3-b]pyridin-5-yl)phenyl]butanamide is CN1CCN(c2cc(NC(=O)C3(c4ccc(-c5cnc(N)nc5)cc4)CCC3)ccn2)CC1.COc1ccc(-c2ccc(NC(=O)C(C)(c3ccc(-c4cnc5[nH]ccc5c4)cc3)C(C)C)nc2)cn1.COc1cncc(-c2ccc(NC(=O)C(C)(c3ccc(-c4cnc5c(c4)CCN5)cc3)C(C)C)nc2)c1.N#Cc1ccc(NC(=O)C2(c3ccc(-c4cnc(N)nc4)cc3)CCC2)cc1.Nc1ncc(-c2ccc(C3(C(=O)Nc4ccc(N5CCOCC5)c(Cl)c4)CCC3)cc2)cn1.
What is the InChIKey of 1-[4-(2-aminopyrimidin-5-yl)phenyl]-N-(3-chloro-4-morpholin-4-ylphenyl)cyclobutane-1-carboxamide;1-[4-(2-aminopyrimidin-5-yl)phenyl]-N-(4-cyanophenyl)cyclobutane-1-carboxamide;1-[4-(2-aminopyrimidin-5-yl)phenyl]-N-[2-(4-methylpiperazin-1-yl)-4-pyridinyl]cyclobutane-1-carboxamide;2-[4-(2,3-dihydro-1H-pyrrolo[2,3-b]pyridin-5-yl)phenyl]-N-[5-(5-methoxy-3-pyridinyl)-2-pyridinyl]-2,3-dimethylbutanamide;N-[5-(6-methoxy-3-pyridinyl)-2-pyridinyl]-2,3-dimethyl-2-[4-(1H-pyrrolo[2,3-b]pyridin-5-yl)phenyl]butanamide?
The InChIKey is AVBQTACALWMICP-UHFFFAOYSA-N. The full InChI is InChI=1S/C30H29N5O2.C30H31N5O2.C25H26ClN5O2.C25H29N7O.C22H19N5O/c1-19(2)30(3,25-9-5-20(6-10-25)24-15-21-13-14-31-28(21)34-18-24)29(36)35-26-11-7-22(16-32-26)23-8-12-27(37-4)33-17-23;1-19(2)30(3,25-8-5-20(6-9-25)23-13-21-11-12-32-28(21)34-17-23)29(36)35-27-10-7-22(16-33-27)24-14-26(37-4)18-31-15-24;26-21-14-20(6-7-22(21)31-10-12-33-13-11-31)30-23(32)25(8-1-9-25)19-4-2-17(3-5-19)18-15-28-24(27)29-16-18;1-31-11-13-32(14-12-31)22-15-21(7-10-27-22)30-23(33)25(8-2-9-25)20-5-3-18(4-6-20)19-16-28-24(26)29-17-19;23-12-15-2-8-19(9-3-15)27-20(28)22(10-1-11-22)18-6-4-16(5-7-18)17-13-25-21(24)26-14-17/h5-19H,1-4H3,(H,31,34)(H,32,35,36);5-10,13-19H,11-12H2,1-4H3,(H,32,34)(H,33,35,36);2-7,14-16H,1,8-13H2,(H,30,32)(H2,27,28,29);3-7,10,15-17H,2,8-9,11-14H2,1H3,(H2,26,28,29)(H,27,30,33);2-9,13-14H,1,10-11H2,(H,27,28)(H2,24,25,26).
What are the key properties of 1-[4-(2-aminopyrimidin-5-yl)phenyl]-N-(3-chloro-4-morpholin-4-ylphenyl)cyclobutane-1-carboxamide;1-[4-(2-aminopyrimidin-5-yl)phenyl]-N-(4-cyanophenyl)cyclobutane-1-carboxamide;1-[4-(2-aminopyrimidin-5-yl)phenyl]-N-[2-(4-methylpiperazin-1-yl)-4-pyridinyl]cyclobutane-1-carboxamide;2-[4-(2,3-dihydro-1H-pyrrolo[2,3-b]pyridin-5-yl)phenyl]-N-[5-(5-methoxy-3-pyridinyl)-2-pyridinyl]-2,3-dimethylbutanamide;N-[5-(6-methoxy-3-pyridinyl)-2-pyridinyl]-2,3-dimethyl-2-[4-(1H-pyrrolo[2,3-b]pyridin-5-yl)phenyl]butanamide?
1-[4-(2-aminopyrimidin-5-yl)phenyl]-N-(3-chloro-4-morpholin-4-ylphenyl)cyclobutane-1-carboxamide;1-[4-(2-aminopyrimidin-5-yl)phenyl]-N-(4-cyanophenyl)cyclobutane-1-carboxamide;1-[4-(2-aminopyrimidin-5-yl)phenyl]-N-[2-(4-methylpiperazin-1-yl)-4-pyridinyl]cyclobutane-1-carboxamide;2-[4-(2,3-dihydro-1H-pyrrolo[2,3-b]pyridin-5-yl)phenyl]-N-[5-(5-methoxy-3-pyridinyl)-2-pyridinyl]-2,3-dimethylbutanamide;N-[5-(6-methoxy-3-pyridinyl)-2-pyridinyl]-2,3-dimethyl-2-[4-(1H-pyrrolo[2,3-b]pyridin-5-yl)phenyl]butanamide has a molecular weight of 2262.16 g/mol, XLogP of 22.85, 28 rotatable bonds, 10 hydrogen bond donors, and 29 hydrogen bond acceptors.
Where does this data come from?
All data for 1-[4-(2-aminopyrimidin-5-yl)phenyl]-N-(3-chloro-4-morpholin-4-ylphenyl)cyclobutane-1-carboxamide;1-[4-(2-aminopyrimidin-5-yl)phenyl]-N-(4-cyanophenyl)cyclobutane-1-carboxamide;1-[4-(2-aminopyrimidin-5-yl)phenyl]-N-[2-(4-methylpiperazin-1-yl)-4-pyridinyl]cyclobutane-1-carboxamide;2-[4-(2,3-dihydro-1H-pyrrolo[2,3-b]pyridin-5-yl)phenyl]-N-[5-(5-methoxy-3-pyridinyl)-2-pyridinyl]-2,3-dimethylbutanamide;N-[5-(6-methoxy-3-pyridinyl)-2-pyridinyl]-2,3-dimethyl-2-[4-(1H-pyrrolo[2,3-b]pyridin-5-yl)phenyl]butanamide is sourced from PubChem (CID 157239835), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).