6-[2-chloro-5-methyl-4-(6-methyl-2-pyridinyl)phenyl]-8-ethyl-2-[[(3S)-oxolan-3-yl]amino]pyrido[2,3-d]pyrimidin-7-one;6-[2-chloro-4-(3-methyl-2-pyridinyl)phenyl]-2-[[(4S)-2,2-dimethyloxan-4-yl]amino]-8-ethylpyrido[2,3-d]pyrimidin-7-one;6-[2-chloro-4-(3-methyl-2-pyridinyl)phenyl]-2-[[(4R)-2,2-dimethyloxan-4-yl]amino]-8-ethylpyrido[2,3-d]pyrimidin-7-one;6-[2-chloro-4-(3-methyl-2-pyridinyl)phenyl]-2-[(1,1-dioxothian-4-yl)amino]-8-ethylpyrido[2,3-d]pyrimidin-7-one;6-[2-chloro-4-(3-methyl-2-pyridinyl)phenyl]-8-ethyl-2-[(1-oxothian-4-yl)amino]pyrido[2,3-d]pyrimidin-7-one

C134H138Cl5N25O11S2 — CID 157254714

About 6-[2-chloro-5-methyl-4-(6-methyl-2-pyridinyl)phenyl]-8-ethyl-2-[[(3S)-oxolan-3-yl]amino]pyrido[2,3-d]pyrimidin-7-one;6-[2-chloro-4-(3-methyl-2-pyridinyl)phenyl]-2-[[(4S)-2,2-dimethyloxan-4-yl]amino]-8-ethylpyrido[2,3-d]pyrimidin-7-one;6-[2-chloro-4-(3-methyl-2-pyridinyl)phenyl]-2-[[(4R)-2,2-dimethyloxan-4-yl]amino]-8-ethylpyrido[2,3-d]pyrimidin-7-one;6-[2-chloro-4-(3-methyl-2-pyridinyl)phenyl]-2-[(1,1-dioxothian-4-yl)amino]-8-ethylpyrido[2,3-d]pyrimidin-7-one;6-[2-chloro-4-(3-methyl-2-pyridinyl)phenyl]-8-ethyl-2-[(1-oxothian-4-yl)amino]pyrido[2,3-d]pyrimidin-7-one

6-[2-chloro-5-methyl-4-(6-methyl-2-pyridinyl)phenyl]-8-ethyl-2-[[(3S)-oxolan-3-yl]amino]pyrido[2,3-d]pyrimidin-7-one;6-[2-chloro-4-(3-methyl-2-pyridinyl)phenyl]-2-[[(4S)-2,2-dimethyloxan-4-yl]amino]-8-ethylpyrido[2,3-d]pyrimidin-7-one;6-[2-chloro-4-(3-methyl-2-pyridinyl)phenyl]-2-[[(4R)-2,2-dimethyloxan-4-yl]amino]-8-ethylpyrido[2,3-d]pyrimidin-7-one;6-[2-chloro-4-(3-methyl-2-pyridinyl)phenyl]-2-[(1,1-dioxothian-4-yl)amino]-8-ethylpyrido[2,3-d]pyrimidin-7-one;6-[2-chloro-4-(3-methyl-2-pyridinyl)phenyl]-8-ethyl-2-[(1-oxothian-4-yl)amino]pyrido[2,3-d]pyrimidin-7-one (PubChem CID 157254714) has the molecular formula C134H138Cl5N25O11S2 and a molecular weight of 2516.14 g/mol. Its IUPAC name is 6-[2-chloro-5-methyl-4-(6-methyl-2-pyridinyl)phenyl]-8-ethyl-2-[[(3S)-oxolan-3-yl]amino]pyrido[2,3-d]pyrimidin-7-one;6-[2-chloro-4-(3-methyl-2-pyridinyl)phenyl]-2-[[(4S)-2,2-dimethyloxan-4-yl]amino]-8-ethylpyrido[2,3-d]pyrimidin-7-one;6-[2-chloro-4-(3-methyl-2-pyridinyl)phenyl]-2-[[(4R)-2,2-dimethyloxan-4-yl]amino]-8-ethylpyrido[2,3-d]pyrimidin-7-one;6-[2-chloro-4-(3-methyl-2-pyridinyl)phenyl]-2-[(1,1-dioxothian-4-yl)amino]-8-ethylpyrido[2,3-d]pyrimidin-7-one;6-[2-chloro-4-(3-methyl-2-pyridinyl)phenyl]-8-ethyl-2-[(1-oxothian-4-yl)amino]pyrido[2,3-d]pyrimidin-7-one.

Molecular Properties

• Compound Name: 6-[2-chloro-5-methyl-4-(6-methyl-2-pyridinyl)phenyl]-8-ethyl-2-[[(3S)-oxolan-3-yl]amino]pyrido[2,3-d]pyrimidin-7-one;6-[2-chloro-4-(3-methyl-2-pyridinyl)phenyl]-2-[[(4S)-2,2-dimethyloxan-4-yl]amino]-8-ethylpyrido[2,3-d]pyrimidin-7-one;6-[2-chloro-4-(3-methyl-2-pyridinyl)phenyl]-2-[[(4R)-2,2-dimethyloxan-4-yl]amino]-8-ethylpyrido[2,3-d]pyrimidin-7-one;6-[2-chloro-4-(3-methyl-2-pyridinyl)phenyl]-2-[(1,1-dioxothian-4-yl)amino]-8-ethylpyrido[2,3-d]pyrimidin-7-one;6-[2-chloro-4-(3-methyl-2-pyridinyl)phenyl]-8-ethyl-2-[(1-oxothian-4-yl)amino]pyrido[2,3-d]pyrimidin-7-one
• PubChem CID: 157254714
• Molecular Formula: C134H138Cl5N25O11S2
• Molecular Weight: 2516.14 g/mol
• Exact Mass: 2511.89
• IUPAC Name: 6-[2-chloro-5-methyl-4-(6-methyl-2-pyridinyl)phenyl]-8-ethyl-2-[[(3S)-oxolan-3-yl]amino]pyrido[2,3-d]pyrimidin-7-one;6-[2-chloro-4-(3-methyl-2-pyridinyl)phenyl]-2-[[(4S)-2,2-dimethyloxan-4-yl]amino]-8-ethylpyrido[2,3-d]pyrimidin-7-one;6-[2-chloro-4-(3-methyl-2-pyridinyl)phenyl]-2-[[(4R)-2,2-dimethyloxan-4-yl]amino]-8-ethylpyrido[2,3-d]pyrimidin-7-one;6-[2-chloro-4-(3-methyl-2-pyridinyl)phenyl]-2-[(1,1-dioxothian-4-yl)amino]-8-ethylpyrido[2,3-d]pyrimidin-7-one;6-[2-chloro-4-(3-methyl-2-pyridinyl)phenyl]-8-ethyl-2-[(1-oxothian-4-yl)amino]pyrido[2,3-d]pyrimidin-7-one
• SMILES: CCn1c(=O)c(-c2cc(C)c(-c3cccc(C)n3)cc2Cl)cc2cnc(N[C@H]3CCOC3)nc21.CCn1c(=O)c(-c2ccc(-c3ncccc3C)cc2Cl)cc2cnc(NC3CCS(=O)(=O)CC3)nc21.CCn1c(=O)c(-c2ccc(-c3ncccc3C)cc2Cl)cc2cnc(NC3CCS(=O)CC3)nc21.CCn1c(=O)c(-c2ccc(-c3ncccc3C)cc2Cl)cc2cnc(N[C@@H]3CCOC(C)(C)C3)nc21.CCn1c(=O)c(-c2ccc(-c3ncccc3C)cc2Cl)cc2cnc(N[C@H]3CCOC(C)(C)C3)nc21
• InChI: InChI=1S/2C28H30ClN5O2.C26H26ClN5O3S.C26H26ClN5O2S.C26H26ClN5O2/c2*1-5-34-25-19(16-31-27(33-25)32-20-10-12-36-28(3,4)15-20)13-22(26(34)35)21-9-8-18(14-23(21)29)24-17(2)7-6-11-30-24;1-3-32-24-18(15-29-26(31-24)30-19-8-11-36(34,35)12-9-19)13-21(25(32)33)20-7-6-17(14-22(20)27)23-16(2)5-4-10-28-23;1-3-32-24-18(15-29-26(31-24)30-19-8-11-35(34)12-9-19)13-21(25(32)33)20-7-6-17(14-22(20)27)23-16(2)5-4-10-28-23;1-4-32-24-17(13-28-26(31-24)30-18-8-9-34-14-18)11-21(25(32)33)20-10-15(2)19(12-22(20)27)23-7-5-6-16(3)29-23/h2*6-9,11,13-14,16,20H,5,10,12,15H2,1-4H3,(H,31,32,33);4-7,10,13-15,19H,3,8-9,11-12H2,1-2H3,(H,29,30,31);4-7,10,13-15,19H,3,8-9,11-12H2,1-2H3,(H,29,30,31);5-7,10-13,18H,4,8-9,14H2,1-3H3,(H,28,30,31)/t2*20-;;;18-/m10..0/s1
• InChIKey: AWTHSNPLUQAXHF-HOGQLSNLSA-N
• XLogP: 26.07
• TPSA: 442.40 Ų
• H-Bond Donors: 5
• H-Bond Acceptors: 36
• Rotatable Bonds: 25
• Heavy Atoms: 177
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	2516.14
LogP ≤ 5	26.07
H-Bond Donors ≤ 5	5
H-Bond Acceptors ≤ 10	36

Frequently Asked Questions

What is the IUPAC name of 6-[2-chloro-5-methyl-4-(6-methyl-2-pyridinyl)phenyl]-8-ethyl-2-[[(3S)-oxolan-3-yl]amino]pyrido[2,3-d]pyrimidin-7-one;6-[2-chloro-4-(3-methyl-2-pyridinyl)phenyl]-2-[[(4S)-2,2-dimethyloxan-4-yl]amino]-8-ethylpyrido[2,3-d]pyrimidin-7-one;6-[2-chloro-4-(3-methyl-2-pyridinyl)phenyl]-2-[[(4R)-2,2-dimethyloxan-4-yl]amino]-8-ethylpyrido[2,3-d]pyrimidin-7-one;6-[2-chloro-4-(3-methyl-2-pyridinyl)phenyl]-2-[(1,1-dioxothian-4-yl)amino]-8-ethylpyrido[2,3-d]pyrimidin-7-one;6-[2-chloro-4-(3-methyl-2-pyridinyl)phenyl]-8-ethyl-2-[(1-oxothian-4-yl)amino]pyrido[2,3-d]pyrimidin-7-one?

The IUPAC name of 6-[2-chloro-5-methyl-4-(6-methyl-2-pyridinyl)phenyl]-8-ethyl-2-[[(3S)-oxolan-3-yl]amino]pyrido[2,3-d]pyrimidin-7-one;6-[2-chloro-4-(3-methyl-2-pyridinyl)phenyl]-2-[[(4S)-2,2-dimethyloxan-4-yl]amino]-8-ethylpyrido[2,3-d]pyrimidin-7-one;6-[2-chloro-4-(3-methyl-2-pyridinyl)phenyl]-2-[[(4R)-2,2-dimethyloxan-4-yl]amino]-8-ethylpyrido[2,3-d]pyrimidin-7-one;6-[2-chloro-4-(3-methyl-2-pyridinyl)phenyl]-2-[(1,1-dioxothian-4-yl)amino]-8-ethylpyrido[2,3-d]pyrimidin-7-one;6-[2-chloro-4-(3-methyl-2-pyridinyl)phenyl]-8-ethyl-2-[(1-oxothian-4-yl)amino]pyrido[2,3-d]pyrimidin-7-one (CID 157254714) is 6-[2-chloro-5-methyl-4-(6-methyl-2-pyridinyl)phenyl]-8-ethyl-2-[[(3S)-oxolan-3-yl]amino]pyrido[2,3-d]pyrimidin-7-one;6-[2-chloro-4-(3-methyl-2-pyridinyl)phenyl]-2-[[(4S)-2,2-dimethyloxan-4-yl]amino]-8-ethylpyrido[2,3-d]pyrimidin-7-one;6-[2-chloro-4-(3-methyl-2-pyridinyl)phenyl]-2-[[(4R)-2,2-dimethyloxan-4-yl]amino]-8-ethylpyrido[2,3-d]pyrimidin-7-one;6-[2-chloro-4-(3-methyl-2-pyridinyl)phenyl]-2-[(1,1-dioxothian-4-yl)amino]-8-ethylpyrido[2,3-d]pyrimidin-7-one;6-[2-chloro-4-(3-methyl-2-pyridinyl)phenyl]-8-ethyl-2-[(1-oxothian-4-yl)amino]pyrido[2,3-d]pyrimidin-7-one.

What is the SMILES notation for 6-[2-chloro-5-methyl-4-(6-methyl-2-pyridinyl)phenyl]-8-ethyl-2-[[(3S)-oxolan-3-yl]amino]pyrido[2,3-d]pyrimidin-7-one;6-[2-chloro-4-(3-methyl-2-pyridinyl)phenyl]-2-[[(4S)-2,2-dimethyloxan-4-yl]amino]-8-ethylpyrido[2,3-d]pyrimidin-7-one;6-[2-chloro-4-(3-methyl-2-pyridinyl)phenyl]-2-[[(4R)-2,2-dimethyloxan-4-yl]amino]-8-ethylpyrido[2,3-d]pyrimidin-7-one;6-[2-chloro-4-(3-methyl-2-pyridinyl)phenyl]-2-[(1,1-dioxothian-4-yl)amino]-8-ethylpyrido[2,3-d]pyrimidin-7-one;6-[2-chloro-4-(3-methyl-2-pyridinyl)phenyl]-8-ethyl-2-[(1-oxothian-4-yl)amino]pyrido[2,3-d]pyrimidin-7-one?

The canonical SMILES for 6-[2-chloro-5-methyl-4-(6-methyl-2-pyridinyl)phenyl]-8-ethyl-2-[[(3S)-oxolan-3-yl]amino]pyrido[2,3-d]pyrimidin-7-one;6-[2-chloro-4-(3-methyl-2-pyridinyl)phenyl]-2-[[(4S)-2,2-dimethyloxan-4-yl]amino]-8-ethylpyrido[2,3-d]pyrimidin-7-one;6-[2-chloro-4-(3-methyl-2-pyridinyl)phenyl]-2-[[(4R)-2,2-dimethyloxan-4-yl]amino]-8-ethylpyrido[2,3-d]pyrimidin-7-one;6-[2-chloro-4-(3-methyl-2-pyridinyl)phenyl]-2-[(1,1-dioxothian-4-yl)amino]-8-ethylpyrido[2,3-d]pyrimidin-7-one;6-[2-chloro-4-(3-methyl-2-pyridinyl)phenyl]-8-ethyl-2-[(1-oxothian-4-yl)amino]pyrido[2,3-d]pyrimidin-7-one is CCn1c(=O)c(-c2cc(C)c(-c3cccc(C)n3)cc2Cl)cc2cnc(N[C@H]3CCOC3)nc21.CCn1c(=O)c(-c2ccc(-c3ncccc3C)cc2Cl)cc2cnc(NC3CCS(=O)(=O)CC3)nc21.CCn1c(=O)c(-c2ccc(-c3ncccc3C)cc2Cl)cc2cnc(NC3CCS(=O)CC3)nc21.CCn1c(=O)c(-c2ccc(-c3ncccc3C)cc2Cl)cc2cnc(N[C@@H]3CCOC(C)(C)C3)nc21.CCn1c(=O)c(-c2ccc(-c3ncccc3C)cc2Cl)cc2cnc(N[C@H]3CCOC(C)(C)C3)nc21.

What is the InChIKey of 6-[2-chloro-5-methyl-4-(6-methyl-2-pyridinyl)phenyl]-8-ethyl-2-[[(3S)-oxolan-3-yl]amino]pyrido[2,3-d]pyrimidin-7-one;6-[2-chloro-4-(3-methyl-2-pyridinyl)phenyl]-2-[[(4S)-2,2-dimethyloxan-4-yl]amino]-8-ethylpyrido[2,3-d]pyrimidin-7-one;6-[2-chloro-4-(3-methyl-2-pyridinyl)phenyl]-2-[[(4R)-2,2-dimethyloxan-4-yl]amino]-8-ethylpyrido[2,3-d]pyrimidin-7-one;6-[2-chloro-4-(3-methyl-2-pyridinyl)phenyl]-2-[(1,1-dioxothian-4-yl)amino]-8-ethylpyrido[2,3-d]pyrimidin-7-one;6-[2-chloro-4-(3-methyl-2-pyridinyl)phenyl]-8-ethyl-2-[(1-oxothian-4-yl)amino]pyrido[2,3-d]pyrimidin-7-one?

The InChIKey is AWTHSNPLUQAXHF-HOGQLSNLSA-N. The full InChI is InChI=1S/2C28H30ClN5O2.C26H26ClN5O3S.C26H26ClN5O2S.C26H26ClN5O2/c2*1-5-34-25-19(16-31-27(33-25)32-20-10-12-36-28(3,4)15-20)13-22(26(34)35)21-9-8-18(14-23(21)29)24-17(2)7-6-11-30-24;1-3-32-24-18(15-29-26(31-24)30-19-8-11-36(34,35)12-9-19)13-21(25(32)33)20-7-6-17(14-22(20)27)23-16(2)5-4-10-28-23;1-3-32-24-18(15-29-26(31-24)30-19-8-11-35(34)12-9-19)13-21(25(32)33)20-7-6-17(14-22(20)27)23-16(2)5-4-10-28-23;1-4-32-24-17(13-28-26(31-24)30-18-8-9-34-14-18)11-21(25(32)33)20-10-15(2)19(12-22(20)27)23-7-5-6-16(3)29-23/h2*6-9,11,13-14,16,20H,5,10,12,15H2,1-4H3,(H,31,32,33);4-7,10,13-15,19H,3,8-9,11-12H2,1-2H3,(H,29,30,31);4-7,10,13-15,19H,3,8-9,11-12H2,1-2H3,(H,29,30,31);5-7,10-13,18H,4,8-9,14H2,1-3H3,(H,28,30,31)/t2*20-;;;18-/m10..0/s1.

What are the key properties of 6-[2-chloro-5-methyl-4-(6-methyl-2-pyridinyl)phenyl]-8-ethyl-2-[[(3S)-oxolan-3-yl]amino]pyrido[2,3-d]pyrimidin-7-one;6-[2-chloro-4-(3-methyl-2-pyridinyl)phenyl]-2-[[(4S)-2,2-dimethyloxan-4-yl]amino]-8-ethylpyrido[2,3-d]pyrimidin-7-one;6-[2-chloro-4-(3-methyl-2-pyridinyl)phenyl]-2-[[(4R)-2,2-dimethyloxan-4-yl]amino]-8-ethylpyrido[2,3-d]pyrimidin-7-one;6-[2-chloro-4-(3-methyl-2-pyridinyl)phenyl]-2-[(1,1-dioxothian-4-yl)amino]-8-ethylpyrido[2,3-d]pyrimidin-7-one;6-[2-chloro-4-(3-methyl-2-pyridinyl)phenyl]-8-ethyl-2-[(1-oxothian-4-yl)amino]pyrido[2,3-d]pyrimidin-7-one?

6-[2-chloro-5-methyl-4-(6-methyl-2-pyridinyl)phenyl]-8-ethyl-2-[[(3S)-oxolan-3-yl]amino]pyrido[2,3-d]pyrimidin-7-one;6-[2-chloro-4-(3-methyl-2-pyridinyl)phenyl]-2-[[(4S)-2,2-dimethyloxan-4-yl]amino]-8-ethylpyrido[2,3-d]pyrimidin-7-one;6-[2-chloro-4-(3-methyl-2-pyridinyl)phenyl]-2-[[(4R)-2,2-dimethyloxan-4-yl]amino]-8-ethylpyrido[2,3-d]pyrimidin-7-one;6-[2-chloro-4-(3-methyl-2-pyridinyl)phenyl]-2-[(1,1-dioxothian-4-yl)amino]-8-ethylpyrido[2,3-d]pyrimidin-7-one;6-[2-chloro-4-(3-methyl-2-pyridinyl)phenyl]-8-ethyl-2-[(1-oxothian-4-yl)amino]pyrido[2,3-d]pyrimidin-7-one has a molecular weight of 2516.14 g/mol, XLogP of 26.07, 25 rotatable bonds, 5 hydrogen bond donors, and 36 hydrogen bond acceptors.

Where does this data come from?

All data for 6-[2-chloro-5-methyl-4-(6-methyl-2-pyridinyl)phenyl]-8-ethyl-2-[[(3S)-oxolan-3-yl]amino]pyrido[2,3-d]pyrimidin-7-one;6-[2-chloro-4-(3-methyl-2-pyridinyl)phenyl]-2-[[(4S)-2,2-dimethyloxan-4-yl]amino]-8-ethylpyrido[2,3-d]pyrimidin-7-one;6-[2-chloro-4-(3-methyl-2-pyridinyl)phenyl]-2-[[(4R)-2,2-dimethyloxan-4-yl]amino]-8-ethylpyrido[2,3-d]pyrimidin-7-one;6-[2-chloro-4-(3-methyl-2-pyridinyl)phenyl]-2-[(1,1-dioxothian-4-yl)amino]-8-ethylpyrido[2,3-d]pyrimidin-7-one;6-[2-chloro-4-(3-methyl-2-pyridinyl)phenyl]-8-ethyl-2-[(1-oxothian-4-yl)amino]pyrido[2,3-d]pyrimidin-7-one is sourced from PubChem (CID 157254714), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).