2-[[2-cyclopropyl-5-[2-(2,3-dihydroxypropanoyl)-2,6-diazaspiro[3.3]heptan-6-yl]-6-fluoropyrazolo[1,5-a]pyridin-3-yl]-methylamino]-4-(4-methylphenyl)-1,3-thiazole-5-carbonitrile;2-[[2-cyclopropyl-6-fluoro-5-[2-(3-hydroxyazetidine-1-carbonyl)-2,6-diazaspiro[3.3]heptan-6-yl]pyrazolo[1,5-a]pyridin-3-yl]-methylamino]-4-(4-methylphenyl)-1,3-thiazole-5-carbonitrile;2-[[2-cyclopropyl-6-fluoro-5-[2-(3-hydroxyazetidine-1-carbonyl)-2,7-diazaspiro[3.4]octan-7-yl]pyrazolo[1,5-a]pyridin-3-yl]-methylamino]-4-(4-methylphenyl)-1,3-thiazole-5-carbonitrile;2-[[2-cyclopropyl-6-fluoro-5-[4-[2-[3-(hydroxymethyl)azetidin-1-yl]-2-oxoethyl]piperazin-1-yl]pyrazolo[1,5-a]pyridin-3-yl]-methylamino]-4-(4-methylphenyl)-1,3-thiazole-5-carbonitrile;2-[[2-cyclopropyl-6-fluoro-5-[2-(4-methylpiperazine-1-carbonyl)-2,6-diazaspiro[3.3]heptan-6-yl]pyrazolo[1,5-a]pyridin-3-yl]-methylamino]-4-(4-methylphenyl)-1,3-thiazole-5-carbonitrile

C158H165F5N40O10S5 — CID 157254737

About 2-[[2-cyclopropyl-5-[2-(2,3-dihydroxypropanoyl)-2,6-diazaspiro[3.3]heptan-6-yl]-6-fluoropyrazolo[1,5-a]pyridin-3-yl]-methylamino]-4-(4-methylphenyl)-1,3-thiazole-5-carbonitrile;2-[[2-cyclopropyl-6-fluoro-5-[2-(3-hydroxyazetidine-1-carbonyl)-2,6-diazaspiro[3.3]heptan-6-yl]pyrazolo[1,5-a]pyridin-3-yl]-methylamino]-4-(4-methylphenyl)-1,3-thiazole-5-carbonitrile;2-[[2-cyclopropyl-6-fluoro-5-[2-(3-hydroxyazetidine-1-carbonyl)-2,7-diazaspiro[3.4]octan-7-yl]pyrazolo[1,5-a]pyridin-3-yl]-methylamino]-4-(4-methylphenyl)-1,3-thiazole-5-carbonitrile;2-[[2-cyclopropyl-6-fluoro-5-[4-[2-[3-(hydroxymethyl)azetidin-1-yl]-2-oxoethyl]piperazin-1-yl]pyrazolo[1,5-a]pyridin-3-yl]-methylamino]-4-(4-methylphenyl)-1,3-thiazole-5-carbonitrile;2-[[2-cyclopropyl-6-fluoro-5-[2-(4-methylpiperazine-1-carbonyl)-2,6-diazaspiro[3.3]heptan-6-yl]pyrazolo[1,5-a]pyridin-3-yl]-methylamino]-4-(4-methylphenyl)-1,3-thiazole-5-carbonitrile

2-[[2-cyclopropyl-5-[2-(2,3-dihydroxypropanoyl)-2,6-diazaspiro[3.3]heptan-6-yl]-6-fluoropyrazolo[1,5-a]pyridin-3-yl]-methylamino]-4-(4-methylphenyl)-1,3-thiazole-5-carbonitrile;2-[[2-cyclopropyl-6-fluoro-5-[2-(3-hydroxyazetidine-1-carbonyl)-2,6-diazaspiro[3.3]heptan-6-yl]pyrazolo[1,5-a]pyridin-3-yl]-methylamino]-4-(4-methylphenyl)-1,3-thiazole-5-carbonitrile;2-[[2-cyclopropyl-6-fluoro-5-[2-(3-hydroxyazetidine-1-carbonyl)-2,7-diazaspiro[3.4]octan-7-yl]pyrazolo[1,5-a]pyridin-3-yl]-methylamino]-4-(4-methylphenyl)-1,3-thiazole-5-carbonitrile;2-[[2-cyclopropyl-6-fluoro-5-[4-[2-[3-(hydroxymethyl)azetidin-1-yl]-2-oxoethyl]piperazin-1-yl]pyrazolo[1,5-a]pyridin-3-yl]-methylamino]-4-(4-methylphenyl)-1,3-thiazole-5-carbonitrile;2-[[2-cyclopropyl-6-fluoro-5-[2-(4-methylpiperazine-1-carbonyl)-2,6-diazaspiro[3.3]heptan-6-yl]pyrazolo[1,5-a]pyridin-3-yl]-methylamino]-4-(4-methylphenyl)-1,3-thiazole-5-carbonitrile (PubChem CID 157254737) has the molecular formula C158H165F5N40O10S5 and a molecular weight of 3039.65 g/mol. Its IUPAC name is 2-[[2-cyclopropyl-5-[2-(2,3-dihydroxypropanoyl)-2,6-diazaspiro[3.3]heptan-6-yl]-6-fluoropyrazolo[1,5-a]pyridin-3-yl]-methylamino]-4-(4-methylphenyl)-1,3-thiazole-5-carbonitrile;2-[[2-cyclopropyl-6-fluoro-5-[2-(3-hydroxyazetidine-1-carbonyl)-2,6-diazaspiro[3.3]heptan-6-yl]pyrazolo[1,5-a]pyridin-3-yl]-methylamino]-4-(4-methylphenyl)-1,3-thiazole-5-carbonitrile;2-[[2-cyclopropyl-6-fluoro-5-[2-(3-hydroxyazetidine-1-carbonyl)-2,7-diazaspiro[3.4]octan-7-yl]pyrazolo[1,5-a]pyridin-3-yl]-methylamino]-4-(4-methylphenyl)-1,3-thiazole-5-carbonitrile;2-[[2-cyclopropyl-6-fluoro-5-[4-[2-[3-(hydroxymethyl)azetidin-1-yl]-2-oxoethyl]piperazin-1-yl]pyrazolo[1,5-a]pyridin-3-yl]-methylamino]-4-(4-methylphenyl)-1,3-thiazole-5-carbonitrile;2-[[2-cyclopropyl-6-fluoro-5-[2-(4-methylpiperazine-1-carbonyl)-2,6-diazaspiro[3.3]heptan-6-yl]pyrazolo[1,5-a]pyridin-3-yl]-methylamino]-4-(4-methylphenyl)-1,3-thiazole-5-carbonitrile.

Molecular Properties

• Compound Name: 2-[[2-cyclopropyl-5-[2-(2,3-dihydroxypropanoyl)-2,6-diazaspiro[3.3]heptan-6-yl]-6-fluoropyrazolo[1,5-a]pyridin-3-yl]-methylamino]-4-(4-methylphenyl)-1,3-thiazole-5-carbonitrile;2-[[2-cyclopropyl-6-fluoro-5-[2-(3-hydroxyazetidine-1-carbonyl)-2,6-diazaspiro[3.3]heptan-6-yl]pyrazolo[1,5-a]pyridin-3-yl]-methylamino]-4-(4-methylphenyl)-1,3-thiazole-5-carbonitrile;2-[[2-cyclopropyl-6-fluoro-5-[2-(3-hydroxyazetidine-1-carbonyl)-2,7-diazaspiro[3.4]octan-7-yl]pyrazolo[1,5-a]pyridin-3-yl]-methylamino]-4-(4-methylphenyl)-1,3-thiazole-5-carbonitrile;2-[[2-cyclopropyl-6-fluoro-5-[4-[2-[3-(hydroxymethyl)azetidin-1-yl]-2-oxoethyl]piperazin-1-yl]pyrazolo[1,5-a]pyridin-3-yl]-methylamino]-4-(4-methylphenyl)-1,3-thiazole-5-carbonitrile;2-[[2-cyclopropyl-6-fluoro-5-[2-(4-methylpiperazine-1-carbonyl)-2,6-diazaspiro[3.3]heptan-6-yl]pyrazolo[1,5-a]pyridin-3-yl]-methylamino]-4-(4-methylphenyl)-1,3-thiazole-5-carbonitrile
• PubChem CID: 157254737
• Molecular Formula: C158H165F5N40O10S5
• Molecular Weight: 3039.65 g/mol
• Exact Mass: 3037.22
• IUPAC Name: 2-[[2-cyclopropyl-5-[2-(2,3-dihydroxypropanoyl)-2,6-diazaspiro[3.3]heptan-6-yl]-6-fluoropyrazolo[1,5-a]pyridin-3-yl]-methylamino]-4-(4-methylphenyl)-1,3-thiazole-5-carbonitrile;2-[[2-cyclopropyl-6-fluoro-5-[2-(3-hydroxyazetidine-1-carbonyl)-2,6-diazaspiro[3.3]heptan-6-yl]pyrazolo[1,5-a]pyridin-3-yl]-methylamino]-4-(4-methylphenyl)-1,3-thiazole-5-carbonitrile;2-[[2-cyclopropyl-6-fluoro-5-[2-(3-hydroxyazetidine-1-carbonyl)-2,7-diazaspiro[3.4]octan-7-yl]pyrazolo[1,5-a]pyridin-3-yl]-methylamino]-4-(4-methylphenyl)-1,3-thiazole-5-carbonitrile;2-[[2-cyclopropyl-6-fluoro-5-[4-[2-[3-(hydroxymethyl)azetidin-1-yl]-2-oxoethyl]piperazin-1-yl]pyrazolo[1,5-a]pyridin-3-yl]-methylamino]-4-(4-methylphenyl)-1,3-thiazole-5-carbonitrile;2-[[2-cyclopropyl-6-fluoro-5-[2-(4-methylpiperazine-1-carbonyl)-2,6-diazaspiro[3.3]heptan-6-yl]pyrazolo[1,5-a]pyridin-3-yl]-methylamino]-4-(4-methylphenyl)-1,3-thiazole-5-carbonitrile
• SMILES: Cc1ccc(-c2nc(N(C)c3c(C4CC4)nn4cc(F)c(N5CC6(CN(C(=O)C(O)CO)C6)C5)cc34)sc2C#N)cc1.Cc1ccc(-c2nc(N(C)c3c(C4CC4)nn4cc(F)c(N5CC6(CN(C(=O)N7CC(O)C7)C6)C5)cc34)sc2C#N)cc1.Cc1ccc(-c2nc(N(C)c3c(C4CC4)nn4cc(F)c(N5CC6(CN(C(=O)N7CCN(C)CC7)C6)C5)cc34)sc2C#N)cc1.Cc1ccc(-c2nc(N(C)c3c(C4CC4)nn4cc(F)c(N5CCC6(CN(C(=O)N7CC(O)C7)C6)C5)cc34)sc2C#N)cc1.Cc1ccc(-c2nc(N(C)c3c(C4CC4)nn4cc(F)c(N5CCN(CC(=O)N6CC(CO)C6)CC5)cc34)sc2C#N)cc1
• InChI: InChI=1S/C33H36FN9OS.C32H33FN8O2S.C32H35FN8O2S.C31H31FN8O2S.C30H30FN7O3S/c1-21-4-6-22(7-5-21)28-27(15-35)45-31(36-28)39(3)30-26-14-25(24(34)16-43(26)37-29(30)23-8-9-23)41-17-33(18-41)19-42(20-33)32(44)40-12-10-38(2)11-13-40;1-19-3-5-20(6-4-19)27-26(12-34)44-30(35-27)37(2)29-25-11-24(23(33)15-41(25)36-28(29)21-7-8-21)38-10-9-32(16-38)17-40(18-32)31(43)39-13-22(42)14-39;1-20-3-5-22(6-4-20)29-27(14-34)44-32(35-29)37(2)31-26-13-25(24(33)17-41(26)36-30(31)23-7-8-23)39-11-9-38(10-12-39)18-28(43)40-15-21(16-40)19-42;1-18-3-5-19(6-4-18)26-25(10-33)43-29(34-26)36(2)28-24-9-23(22(32)13-40(24)35-27(28)20-7-8-20)38-14-31(15-38)16-39(17-31)30(42)37-11-21(41)12-37;1-17-3-5-18(6-4-17)25-24(10-32)42-29(33-25)35(2)27-22-9-21(20(31)11-38(22)34-26(27)19-7-8-19)36-13-30(14-36)15-37(16-30)28(41)23(40)12-39/h4-7,14,16,23H,8-13,17-20H2,1-3H3;3-6,11,15,21-22,42H,7-10,13-14,16-18H2,1-2H3;3-6,13,17,21,23,42H,7-12,15-16,18-19H2,1-2H3;3-6,9,13,20-21,41H,7-8,11-12,14-17H2,1-2H3;3-6,9,11,19,23,39-40H,7-8,12-16H2,1-2H3
• InChIKey: AWTIYWFEYDBCFZ-UHFFFAOYSA-N
• XLogP: 21.40
• TPSA: 521.20 Ų
• H-Bond Donors: 5
• H-Bond Acceptors: 47
• Rotatable Bonds: 30
• Heavy Atoms: 218
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	3039.65
LogP ≤ 5	21.40
H-Bond Donors ≤ 5	5
H-Bond Acceptors ≤ 10	47

Frequently Asked Questions

What is the IUPAC name of 2-[[2-cyclopropyl-5-[2-(2,3-dihydroxypropanoyl)-2,6-diazaspiro[3.3]heptan-6-yl]-6-fluoropyrazolo[1,5-a]pyridin-3-yl]-methylamino]-4-(4-methylphenyl)-1,3-thiazole-5-carbonitrile;2-[[2-cyclopropyl-6-fluoro-5-[2-(3-hydroxyazetidine-1-carbonyl)-2,6-diazaspiro[3.3]heptan-6-yl]pyrazolo[1,5-a]pyridin-3-yl]-methylamino]-4-(4-methylphenyl)-1,3-thiazole-5-carbonitrile;2-[[2-cyclopropyl-6-fluoro-5-[2-(3-hydroxyazetidine-1-carbonyl)-2,7-diazaspiro[3.4]octan-7-yl]pyrazolo[1,5-a]pyridin-3-yl]-methylamino]-4-(4-methylphenyl)-1,3-thiazole-5-carbonitrile;2-[[2-cyclopropyl-6-fluoro-5-[4-[2-[3-(hydroxymethyl)azetidin-1-yl]-2-oxoethyl]piperazin-1-yl]pyrazolo[1,5-a]pyridin-3-yl]-methylamino]-4-(4-methylphenyl)-1,3-thiazole-5-carbonitrile;2-[[2-cyclopropyl-6-fluoro-5-[2-(4-methylpiperazine-1-carbonyl)-2,6-diazaspiro[3.3]heptan-6-yl]pyrazolo[1,5-a]pyridin-3-yl]-methylamino]-4-(4-methylphenyl)-1,3-thiazole-5-carbonitrile?

The IUPAC name of 2-[[2-cyclopropyl-5-[2-(2,3-dihydroxypropanoyl)-2,6-diazaspiro[3.3]heptan-6-yl]-6-fluoropyrazolo[1,5-a]pyridin-3-yl]-methylamino]-4-(4-methylphenyl)-1,3-thiazole-5-carbonitrile;2-[[2-cyclopropyl-6-fluoro-5-[2-(3-hydroxyazetidine-1-carbonyl)-2,6-diazaspiro[3.3]heptan-6-yl]pyrazolo[1,5-a]pyridin-3-yl]-methylamino]-4-(4-methylphenyl)-1,3-thiazole-5-carbonitrile;2-[[2-cyclopropyl-6-fluoro-5-[2-(3-hydroxyazetidine-1-carbonyl)-2,7-diazaspiro[3.4]octan-7-yl]pyrazolo[1,5-a]pyridin-3-yl]-methylamino]-4-(4-methylphenyl)-1,3-thiazole-5-carbonitrile;2-[[2-cyclopropyl-6-fluoro-5-[4-[2-[3-(hydroxymethyl)azetidin-1-yl]-2-oxoethyl]piperazin-1-yl]pyrazolo[1,5-a]pyridin-3-yl]-methylamino]-4-(4-methylphenyl)-1,3-thiazole-5-carbonitrile;2-[[2-cyclopropyl-6-fluoro-5-[2-(4-methylpiperazine-1-carbonyl)-2,6-diazaspiro[3.3]heptan-6-yl]pyrazolo[1,5-a]pyridin-3-yl]-methylamino]-4-(4-methylphenyl)-1,3-thiazole-5-carbonitrile (CID 157254737) is 2-[[2-cyclopropyl-5-[2-(2,3-dihydroxypropanoyl)-2,6-diazaspiro[3.3]heptan-6-yl]-6-fluoropyrazolo[1,5-a]pyridin-3-yl]-methylamino]-4-(4-methylphenyl)-1,3-thiazole-5-carbonitrile;2-[[2-cyclopropyl-6-fluoro-5-[2-(3-hydroxyazetidine-1-carbonyl)-2,6-diazaspiro[3.3]heptan-6-yl]pyrazolo[1,5-a]pyridin-3-yl]-methylamino]-4-(4-methylphenyl)-1,3-thiazole-5-carbonitrile;2-[[2-cyclopropyl-6-fluoro-5-[2-(3-hydroxyazetidine-1-carbonyl)-2,7-diazaspiro[3.4]octan-7-yl]pyrazolo[1,5-a]pyridin-3-yl]-methylamino]-4-(4-methylphenyl)-1,3-thiazole-5-carbonitrile;2-[[2-cyclopropyl-6-fluoro-5-[4-[2-[3-(hydroxymethyl)azetidin-1-yl]-2-oxoethyl]piperazin-1-yl]pyrazolo[1,5-a]pyridin-3-yl]-methylamino]-4-(4-methylphenyl)-1,3-thiazole-5-carbonitrile;2-[[2-cyclopropyl-6-fluoro-5-[2-(4-methylpiperazine-1-carbonyl)-2,6-diazaspiro[3.3]heptan-6-yl]pyrazolo[1,5-a]pyridin-3-yl]-methylamino]-4-(4-methylphenyl)-1,3-thiazole-5-carbonitrile.

What is the SMILES notation for 2-[[2-cyclopropyl-5-[2-(2,3-dihydroxypropanoyl)-2,6-diazaspiro[3.3]heptan-6-yl]-6-fluoropyrazolo[1,5-a]pyridin-3-yl]-methylamino]-4-(4-methylphenyl)-1,3-thiazole-5-carbonitrile;2-[[2-cyclopropyl-6-fluoro-5-[2-(3-hydroxyazetidine-1-carbonyl)-2,6-diazaspiro[3.3]heptan-6-yl]pyrazolo[1,5-a]pyridin-3-yl]-methylamino]-4-(4-methylphenyl)-1,3-thiazole-5-carbonitrile;2-[[2-cyclopropyl-6-fluoro-5-[2-(3-hydroxyazetidine-1-carbonyl)-2,7-diazaspiro[3.4]octan-7-yl]pyrazolo[1,5-a]pyridin-3-yl]-methylamino]-4-(4-methylphenyl)-1,3-thiazole-5-carbonitrile;2-[[2-cyclopropyl-6-fluoro-5-[4-[2-[3-(hydroxymethyl)azetidin-1-yl]-2-oxoethyl]piperazin-1-yl]pyrazolo[1,5-a]pyridin-3-yl]-methylamino]-4-(4-methylphenyl)-1,3-thiazole-5-carbonitrile;2-[[2-cyclopropyl-6-fluoro-5-[2-(4-methylpiperazine-1-carbonyl)-2,6-diazaspiro[3.3]heptan-6-yl]pyrazolo[1,5-a]pyridin-3-yl]-methylamino]-4-(4-methylphenyl)-1,3-thiazole-5-carbonitrile?

The canonical SMILES for 2-[[2-cyclopropyl-5-[2-(2,3-dihydroxypropanoyl)-2,6-diazaspiro[3.3]heptan-6-yl]-6-fluoropyrazolo[1,5-a]pyridin-3-yl]-methylamino]-4-(4-methylphenyl)-1,3-thiazole-5-carbonitrile;2-[[2-cyclopropyl-6-fluoro-5-[2-(3-hydroxyazetidine-1-carbonyl)-2,6-diazaspiro[3.3]heptan-6-yl]pyrazolo[1,5-a]pyridin-3-yl]-methylamino]-4-(4-methylphenyl)-1,3-thiazole-5-carbonitrile;2-[[2-cyclopropyl-6-fluoro-5-[2-(3-hydroxyazetidine-1-carbonyl)-2,7-diazaspiro[3.4]octan-7-yl]pyrazolo[1,5-a]pyridin-3-yl]-methylamino]-4-(4-methylphenyl)-1,3-thiazole-5-carbonitrile;2-[[2-cyclopropyl-6-fluoro-5-[4-[2-[3-(hydroxymethyl)azetidin-1-yl]-2-oxoethyl]piperazin-1-yl]pyrazolo[1,5-a]pyridin-3-yl]-methylamino]-4-(4-methylphenyl)-1,3-thiazole-5-carbonitrile;2-[[2-cyclopropyl-6-fluoro-5-[2-(4-methylpiperazine-1-carbonyl)-2,6-diazaspiro[3.3]heptan-6-yl]pyrazolo[1,5-a]pyridin-3-yl]-methylamino]-4-(4-methylphenyl)-1,3-thiazole-5-carbonitrile is Cc1ccc(-c2nc(N(C)c3c(C4CC4)nn4cc(F)c(N5CC6(CN(C(=O)C(O)CO)C6)C5)cc34)sc2C#N)cc1.Cc1ccc(-c2nc(N(C)c3c(C4CC4)nn4cc(F)c(N5CC6(CN(C(=O)N7CC(O)C7)C6)C5)cc34)sc2C#N)cc1.Cc1ccc(-c2nc(N(C)c3c(C4CC4)nn4cc(F)c(N5CC6(CN(C(=O)N7CCN(C)CC7)C6)C5)cc34)sc2C#N)cc1.Cc1ccc(-c2nc(N(C)c3c(C4CC4)nn4cc(F)c(N5CCC6(CN(C(=O)N7CC(O)C7)C6)C5)cc34)sc2C#N)cc1.Cc1ccc(-c2nc(N(C)c3c(C4CC4)nn4cc(F)c(N5CCN(CC(=O)N6CC(CO)C6)CC5)cc34)sc2C#N)cc1.

What is the InChIKey of 2-[[2-cyclopropyl-5-[2-(2,3-dihydroxypropanoyl)-2,6-diazaspiro[3.3]heptan-6-yl]-6-fluoropyrazolo[1,5-a]pyridin-3-yl]-methylamino]-4-(4-methylphenyl)-1,3-thiazole-5-carbonitrile;2-[[2-cyclopropyl-6-fluoro-5-[2-(3-hydroxyazetidine-1-carbonyl)-2,6-diazaspiro[3.3]heptan-6-yl]pyrazolo[1,5-a]pyridin-3-yl]-methylamino]-4-(4-methylphenyl)-1,3-thiazole-5-carbonitrile;2-[[2-cyclopropyl-6-fluoro-5-[2-(3-hydroxyazetidine-1-carbonyl)-2,7-diazaspiro[3.4]octan-7-yl]pyrazolo[1,5-a]pyridin-3-yl]-methylamino]-4-(4-methylphenyl)-1,3-thiazole-5-carbonitrile;2-[[2-cyclopropyl-6-fluoro-5-[4-[2-[3-(hydroxymethyl)azetidin-1-yl]-2-oxoethyl]piperazin-1-yl]pyrazolo[1,5-a]pyridin-3-yl]-methylamino]-4-(4-methylphenyl)-1,3-thiazole-5-carbonitrile;2-[[2-cyclopropyl-6-fluoro-5-[2-(4-methylpiperazine-1-carbonyl)-2,6-diazaspiro[3.3]heptan-6-yl]pyrazolo[1,5-a]pyridin-3-yl]-methylamino]-4-(4-methylphenyl)-1,3-thiazole-5-carbonitrile?

The InChIKey is AWTIYWFEYDBCFZ-UHFFFAOYSA-N. The full InChI is InChI=1S/C33H36FN9OS.C32H33FN8O2S.C32H35FN8O2S.C31H31FN8O2S.C30H30FN7O3S/c1-21-4-6-22(7-5-21)28-27(15-35)45-31(36-28)39(3)30-26-14-25(24(34)16-43(26)37-29(30)23-8-9-23)41-17-33(18-41)19-42(20-33)32(44)40-12-10-38(2)11-13-40;1-19-3-5-20(6-4-19)27-26(12-34)44-30(35-27)37(2)29-25-11-24(23(33)15-41(25)36-28(29)21-7-8-21)38-10-9-32(16-38)17-40(18-32)31(43)39-13-22(42)14-39;1-20-3-5-22(6-4-20)29-27(14-34)44-32(35-29)37(2)31-26-13-25(24(33)17-41(26)36-30(31)23-7-8-23)39-11-9-38(10-12-39)18-28(43)40-15-21(16-40)19-42;1-18-3-5-19(6-4-18)26-25(10-33)43-29(34-26)36(2)28-24-9-23(22(32)13-40(24)35-27(28)20-7-8-20)38-14-31(15-38)16-39(17-31)30(42)37-11-21(41)12-37;1-17-3-5-18(6-4-17)25-24(10-32)42-29(33-25)35(2)27-22-9-21(20(31)11-38(22)34-26(27)19-7-8-19)36-13-30(14-36)15-37(16-30)28(41)23(40)12-39/h4-7,14,16,23H,8-13,17-20H2,1-3H3;3-6,11,15,21-22,42H,7-10,13-14,16-18H2,1-2H3;3-6,13,17,21,23,42H,7-12,15-16,18-19H2,1-2H3;3-6,9,13,20-21,41H,7-8,11-12,14-17H2,1-2H3;3-6,9,11,19,23,39-40H,7-8,12-16H2,1-2H3.

What are the key properties of 2-[[2-cyclopropyl-5-[2-(2,3-dihydroxypropanoyl)-2,6-diazaspiro[3.3]heptan-6-yl]-6-fluoropyrazolo[1,5-a]pyridin-3-yl]-methylamino]-4-(4-methylphenyl)-1,3-thiazole-5-carbonitrile;2-[[2-cyclopropyl-6-fluoro-5-[2-(3-hydroxyazetidine-1-carbonyl)-2,6-diazaspiro[3.3]heptan-6-yl]pyrazolo[1,5-a]pyridin-3-yl]-methylamino]-4-(4-methylphenyl)-1,3-thiazole-5-carbonitrile;2-[[2-cyclopropyl-6-fluoro-5-[2-(3-hydroxyazetidine-1-carbonyl)-2,7-diazaspiro[3.4]octan-7-yl]pyrazolo[1,5-a]pyridin-3-yl]-methylamino]-4-(4-methylphenyl)-1,3-thiazole-5-carbonitrile;2-[[2-cyclopropyl-6-fluoro-5-[4-[2-[3-(hydroxymethyl)azetidin-1-yl]-2-oxoethyl]piperazin-1-yl]pyrazolo[1,5-a]pyridin-3-yl]-methylamino]-4-(4-methylphenyl)-1,3-thiazole-5-carbonitrile;2-[[2-cyclopropyl-6-fluoro-5-[2-(4-methylpiperazine-1-carbonyl)-2,6-diazaspiro[3.3]heptan-6-yl]pyrazolo[1,5-a]pyridin-3-yl]-methylamino]-4-(4-methylphenyl)-1,3-thiazole-5-carbonitrile?

2-[[2-cyclopropyl-5-[2-(2,3-dihydroxypropanoyl)-2,6-diazaspiro[3.3]heptan-6-yl]-6-fluoropyrazolo[1,5-a]pyridin-3-yl]-methylamino]-4-(4-methylphenyl)-1,3-thiazole-5-carbonitrile;2-[[2-cyclopropyl-6-fluoro-5-[2-(3-hydroxyazetidine-1-carbonyl)-2,6-diazaspiro[3.3]heptan-6-yl]pyrazolo[1,5-a]pyridin-3-yl]-methylamino]-4-(4-methylphenyl)-1,3-thiazole-5-carbonitrile;2-[[2-cyclopropyl-6-fluoro-5-[2-(3-hydroxyazetidine-1-carbonyl)-2,7-diazaspiro[3.4]octan-7-yl]pyrazolo[1,5-a]pyridin-3-yl]-methylamino]-4-(4-methylphenyl)-1,3-thiazole-5-carbonitrile;2-[[2-cyclopropyl-6-fluoro-5-[4-[2-[3-(hydroxymethyl)azetidin-1-yl]-2-oxoethyl]piperazin-1-yl]pyrazolo[1,5-a]pyridin-3-yl]-methylamino]-4-(4-methylphenyl)-1,3-thiazole-5-carbonitrile;2-[[2-cyclopropyl-6-fluoro-5-[2-(4-methylpiperazine-1-carbonyl)-2,6-diazaspiro[3.3]heptan-6-yl]pyrazolo[1,5-a]pyridin-3-yl]-methylamino]-4-(4-methylphenyl)-1,3-thiazole-5-carbonitrile has a molecular weight of 3039.65 g/mol, XLogP of 21.40, 30 rotatable bonds, 5 hydrogen bond donors, and 47 hydrogen bond acceptors.

Where does this data come from?

All data for 2-[[2-cyclopropyl-5-[2-(2,3-dihydroxypropanoyl)-2,6-diazaspiro[3.3]heptan-6-yl]-6-fluoropyrazolo[1,5-a]pyridin-3-yl]-methylamino]-4-(4-methylphenyl)-1,3-thiazole-5-carbonitrile;2-[[2-cyclopropyl-6-fluoro-5-[2-(3-hydroxyazetidine-1-carbonyl)-2,6-diazaspiro[3.3]heptan-6-yl]pyrazolo[1,5-a]pyridin-3-yl]-methylamino]-4-(4-methylphenyl)-1,3-thiazole-5-carbonitrile;2-[[2-cyclopropyl-6-fluoro-5-[2-(3-hydroxyazetidine-1-carbonyl)-2,7-diazaspiro[3.4]octan-7-yl]pyrazolo[1,5-a]pyridin-3-yl]-methylamino]-4-(4-methylphenyl)-1,3-thiazole-5-carbonitrile;2-[[2-cyclopropyl-6-fluoro-5-[4-[2-[3-(hydroxymethyl)azetidin-1-yl]-2-oxoethyl]piperazin-1-yl]pyrazolo[1,5-a]pyridin-3-yl]-methylamino]-4-(4-methylphenyl)-1,3-thiazole-5-carbonitrile;2-[[2-cyclopropyl-6-fluoro-5-[2-(4-methylpiperazine-1-carbonyl)-2,6-diazaspiro[3.3]heptan-6-yl]pyrazolo[1,5-a]pyridin-3-yl]-methylamino]-4-(4-methylphenyl)-1,3-thiazole-5-carbonitrile is sourced from PubChem (CID 157254737), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).