N-(4-chloro-3-pyridin-2-ylphenyl)-6-[[(2S)-2-hydroxypropyl]amino]-2-methylpyridine-3-carboxamide;N-(4-chloro-3-pyridin-2-ylphenyl)-6-[[(2R)-2-hydroxypropyl]amino]-2-methylpyridine-3-carboxamide;N-(4-chloro-3-pyridin-2-ylphenyl)-2-methyl-6-piperazin-1-ylpyridine-3-carboxamide;N-(4-chloro-3-pyridin-2-ylphenyl)-2-methyl-6-pyrazol-1-ylpyridine-3-carboxamide

C85H80Cl4N18O6 — CID 157264133

About N-(4-chloro-3-pyridin-2-ylphenyl)-6-[[(2S)-2-hydroxypropyl]amino]-2-methylpyridine-3-carboxamide;N-(4-chloro-3-pyridin-2-ylphenyl)-6-[[(2R)-2-hydroxypropyl]amino]-2-methylpyridine-3-carboxamide;N-(4-chloro-3-pyridin-2-ylphenyl)-2-methyl-6-piperazin-1-ylpyridine-3-carboxamide;N-(4-chloro-3-pyridin-2-ylphenyl)-2-methyl-6-pyrazol-1-ylpyridine-3-carboxamide

N-(4-chloro-3-pyridin-2-ylphenyl)-6-[[(2S)-2-hydroxypropyl]amino]-2-methylpyridine-3-carboxamide;N-(4-chloro-3-pyridin-2-ylphenyl)-6-[[(2R)-2-hydroxypropyl]amino]-2-methylpyridine-3-carboxamide;N-(4-chloro-3-pyridin-2-ylphenyl)-2-methyl-6-piperazin-1-ylpyridine-3-carboxamide;N-(4-chloro-3-pyridin-2-ylphenyl)-2-methyl-6-pyrazol-1-ylpyridine-3-carboxamide (PubChem CID 157264133) has the molecular formula C85H80Cl4N18O6 and a molecular weight of 1591.51 g/mol. Its IUPAC name is N-(4-chloro-3-pyridin-2-ylphenyl)-6-[[(2S)-2-hydroxypropyl]amino]-2-methylpyridine-3-carboxamide;N-(4-chloro-3-pyridin-2-ylphenyl)-6-[[(2R)-2-hydroxypropyl]amino]-2-methylpyridine-3-carboxamide;N-(4-chloro-3-pyridin-2-ylphenyl)-2-methyl-6-piperazin-1-ylpyridine-3-carboxamide;N-(4-chloro-3-pyridin-2-ylphenyl)-2-methyl-6-pyrazol-1-ylpyridine-3-carboxamide.

Molecular Properties

• Compound Name: N-(4-chloro-3-pyridin-2-ylphenyl)-6-[[(2S)-2-hydroxypropyl]amino]-2-methylpyridine-3-carboxamide;N-(4-chloro-3-pyridin-2-ylphenyl)-6-[[(2R)-2-hydroxypropyl]amino]-2-methylpyridine-3-carboxamide;N-(4-chloro-3-pyridin-2-ylphenyl)-2-methyl-6-piperazin-1-ylpyridine-3-carboxamide;N-(4-chloro-3-pyridin-2-ylphenyl)-2-methyl-6-pyrazol-1-ylpyridine-3-carboxamide
• PubChem CID: 157264133
• Molecular Formula: C85H80Cl4N18O6
• Molecular Weight: 1591.51 g/mol
• Exact Mass: 1588.53
• IUPAC Name: N-(4-chloro-3-pyridin-2-ylphenyl)-6-[[(2S)-2-hydroxypropyl]amino]-2-methylpyridine-3-carboxamide;N-(4-chloro-3-pyridin-2-ylphenyl)-6-[[(2R)-2-hydroxypropyl]amino]-2-methylpyridine-3-carboxamide;N-(4-chloro-3-pyridin-2-ylphenyl)-2-methyl-6-piperazin-1-ylpyridine-3-carboxamide;N-(4-chloro-3-pyridin-2-ylphenyl)-2-methyl-6-pyrazol-1-ylpyridine-3-carboxamide
• SMILES: Cc1nc(-n2cccn2)ccc1C(=O)Nc1ccc(Cl)c(-c2ccccn2)c1.Cc1nc(N2CCNCC2)ccc1C(=O)Nc1ccc(Cl)c(-c2ccccn2)c1.Cc1nc(NC[C@@H](C)O)ccc1C(=O)Nc1ccc(Cl)c(-c2ccccn2)c1.Cc1nc(NC[C@H](C)O)ccc1C(=O)Nc1ccc(Cl)c(-c2ccccn2)c1
• InChI: InChI=1S/C22H22ClN5O.C21H16ClN5O.2C21H21ClN4O2/c1-15-17(6-8-21(26-15)28-12-10-24-11-13-28)22(29)27-16-5-7-19(23)18(14-16)20-4-2-3-9-25-20;1-14-16(7-9-20(25-14)27-12-4-11-24-27)21(28)26-15-6-8-18(22)17(13-15)19-5-2-3-10-23-19;2*1-13(27)12-24-20-9-7-16(14(2)25-20)21(28)26-15-6-8-18(22)17(11-15)19-5-3-4-10-23-19/h2-9,14,24H,10-13H2,1H3,(H,27,29);2-13H,1H3,(H,26,28);2*3-11,13,27H,12H2,1-2H3,(H,24,25)(H,26,28)/t;;2*13-/m..10/s1
• InChIKey: AXUNGSWIVMDAIR-RLOANGSQSA-N
• XLogP: 16.61
• TPSA: 317.13 Ų
• H-Bond Donors: 9
• H-Bond Acceptors: 20
• Rotatable Bonds: 20
• Heavy Atoms: 113
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	1591.51
LogP ≤ 5	16.61
H-Bond Donors ≤ 5	9
H-Bond Acceptors ≤ 10	20

Frequently Asked Questions

What is the IUPAC name of N-(4-chloro-3-pyridin-2-ylphenyl)-6-[[(2S)-2-hydroxypropyl]amino]-2-methylpyridine-3-carboxamide;N-(4-chloro-3-pyridin-2-ylphenyl)-6-[[(2R)-2-hydroxypropyl]amino]-2-methylpyridine-3-carboxamide;N-(4-chloro-3-pyridin-2-ylphenyl)-2-methyl-6-piperazin-1-ylpyridine-3-carboxamide;N-(4-chloro-3-pyridin-2-ylphenyl)-2-methyl-6-pyrazol-1-ylpyridine-3-carboxamide?

The IUPAC name of N-(4-chloro-3-pyridin-2-ylphenyl)-6-[[(2S)-2-hydroxypropyl]amino]-2-methylpyridine-3-carboxamide;N-(4-chloro-3-pyridin-2-ylphenyl)-6-[[(2R)-2-hydroxypropyl]amino]-2-methylpyridine-3-carboxamide;N-(4-chloro-3-pyridin-2-ylphenyl)-2-methyl-6-piperazin-1-ylpyridine-3-carboxamide;N-(4-chloro-3-pyridin-2-ylphenyl)-2-methyl-6-pyrazol-1-ylpyridine-3-carboxamide (CID 157264133) is N-(4-chloro-3-pyridin-2-ylphenyl)-6-[[(2S)-2-hydroxypropyl]amino]-2-methylpyridine-3-carboxamide;N-(4-chloro-3-pyridin-2-ylphenyl)-6-[[(2R)-2-hydroxypropyl]amino]-2-methylpyridine-3-carboxamide;N-(4-chloro-3-pyridin-2-ylphenyl)-2-methyl-6-piperazin-1-ylpyridine-3-carboxamide;N-(4-chloro-3-pyridin-2-ylphenyl)-2-methyl-6-pyrazol-1-ylpyridine-3-carboxamide.

What is the SMILES notation for N-(4-chloro-3-pyridin-2-ylphenyl)-6-[[(2S)-2-hydroxypropyl]amino]-2-methylpyridine-3-carboxamide;N-(4-chloro-3-pyridin-2-ylphenyl)-6-[[(2R)-2-hydroxypropyl]amino]-2-methylpyridine-3-carboxamide;N-(4-chloro-3-pyridin-2-ylphenyl)-2-methyl-6-piperazin-1-ylpyridine-3-carboxamide;N-(4-chloro-3-pyridin-2-ylphenyl)-2-methyl-6-pyrazol-1-ylpyridine-3-carboxamide?

The canonical SMILES for N-(4-chloro-3-pyridin-2-ylphenyl)-6-[[(2S)-2-hydroxypropyl]amino]-2-methylpyridine-3-carboxamide;N-(4-chloro-3-pyridin-2-ylphenyl)-6-[[(2R)-2-hydroxypropyl]amino]-2-methylpyridine-3-carboxamide;N-(4-chloro-3-pyridin-2-ylphenyl)-2-methyl-6-piperazin-1-ylpyridine-3-carboxamide;N-(4-chloro-3-pyridin-2-ylphenyl)-2-methyl-6-pyrazol-1-ylpyridine-3-carboxamide is Cc1nc(-n2cccn2)ccc1C(=O)Nc1ccc(Cl)c(-c2ccccn2)c1.Cc1nc(N2CCNCC2)ccc1C(=O)Nc1ccc(Cl)c(-c2ccccn2)c1.Cc1nc(NC[C@@H](C)O)ccc1C(=O)Nc1ccc(Cl)c(-c2ccccn2)c1.Cc1nc(NC[C@H](C)O)ccc1C(=O)Nc1ccc(Cl)c(-c2ccccn2)c1.

What is the InChIKey of N-(4-chloro-3-pyridin-2-ylphenyl)-6-[[(2S)-2-hydroxypropyl]amino]-2-methylpyridine-3-carboxamide;N-(4-chloro-3-pyridin-2-ylphenyl)-6-[[(2R)-2-hydroxypropyl]amino]-2-methylpyridine-3-carboxamide;N-(4-chloro-3-pyridin-2-ylphenyl)-2-methyl-6-piperazin-1-ylpyridine-3-carboxamide;N-(4-chloro-3-pyridin-2-ylphenyl)-2-methyl-6-pyrazol-1-ylpyridine-3-carboxamide?

The InChIKey is AXUNGSWIVMDAIR-RLOANGSQSA-N. The full InChI is InChI=1S/C22H22ClN5O.C21H16ClN5O.2C21H21ClN4O2/c1-15-17(6-8-21(26-15)28-12-10-24-11-13-28)22(29)27-16-5-7-19(23)18(14-16)20-4-2-3-9-25-20;1-14-16(7-9-20(25-14)27-12-4-11-24-27)21(28)26-15-6-8-18(22)17(13-15)19-5-2-3-10-23-19;2*1-13(27)12-24-20-9-7-16(14(2)25-20)21(28)26-15-6-8-18(22)17(11-15)19-5-3-4-10-23-19/h2-9,14,24H,10-13H2,1H3,(H,27,29);2-13H,1H3,(H,26,28);2*3-11,13,27H,12H2,1-2H3,(H,24,25)(H,26,28)/t;;2*13-/m..10/s1.

What are the key properties of N-(4-chloro-3-pyridin-2-ylphenyl)-6-[[(2S)-2-hydroxypropyl]amino]-2-methylpyridine-3-carboxamide;N-(4-chloro-3-pyridin-2-ylphenyl)-6-[[(2R)-2-hydroxypropyl]amino]-2-methylpyridine-3-carboxamide;N-(4-chloro-3-pyridin-2-ylphenyl)-2-methyl-6-piperazin-1-ylpyridine-3-carboxamide;N-(4-chloro-3-pyridin-2-ylphenyl)-2-methyl-6-pyrazol-1-ylpyridine-3-carboxamide?

N-(4-chloro-3-pyridin-2-ylphenyl)-6-[[(2S)-2-hydroxypropyl]amino]-2-methylpyridine-3-carboxamide;N-(4-chloro-3-pyridin-2-ylphenyl)-6-[[(2R)-2-hydroxypropyl]amino]-2-methylpyridine-3-carboxamide;N-(4-chloro-3-pyridin-2-ylphenyl)-2-methyl-6-piperazin-1-ylpyridine-3-carboxamide;N-(4-chloro-3-pyridin-2-ylphenyl)-2-methyl-6-pyrazol-1-ylpyridine-3-carboxamide has a molecular weight of 1591.51 g/mol, XLogP of 16.61, 20 rotatable bonds, 9 hydrogen bond donors, and 20 hydrogen bond acceptors.

Where does this data come from?

All data for N-(4-chloro-3-pyridin-2-ylphenyl)-6-[[(2S)-2-hydroxypropyl]amino]-2-methylpyridine-3-carboxamide;N-(4-chloro-3-pyridin-2-ylphenyl)-6-[[(2R)-2-hydroxypropyl]amino]-2-methylpyridine-3-carboxamide;N-(4-chloro-3-pyridin-2-ylphenyl)-2-methyl-6-piperazin-1-ylpyridine-3-carboxamide;N-(4-chloro-3-pyridin-2-ylphenyl)-2-methyl-6-pyrazol-1-ylpyridine-3-carboxamide is sourced from PubChem (CID 157264133), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).