[(3'S,5R)-2-chlorospiro[7,8-dihydro-6H-quinoline-5,4'-pyrrolidine]-3'-yl]-[(2S,4R)-2-cyclohexyl-4-phenylpiperidin-1-yl]methanone;[(3'S,5R)-2-chlorospiro[7,8-dihydro-6H-quinoline-5,4'-pyrrolidine]-3'-yl]-[(2R,4S)-2-cyclohexyl-4-phenylpiperidin-1-yl]methanone;[(3'S,5R)-2-chlorospiro[7,8-dihydro-6H-quinoline-5,4'-pyrrolidine]-3'-yl]-[(2R,4R)-2-cyclohexyl-4-phenylpiperidin-1-yl]methanone;[(3'S,4R)-1,1-dioxospiro[2,3-dihydrothiochromene-4,4'-pyrrolidine]-3'-yl]-(4-phenylpiperidin-1-yl)methanone;[(3'S,5R)-2-methylspiro[7,8-dihydro-6H-quinoline-5,4'-pyrrolidine]-3'-yl]-(4-phenylpiperidin-1-yl)methanone

C139H173Cl3N14O7S — CID 157265182

About [(3'S,5R)-2-chlorospiro[7,8-dihydro-6H-quinoline-5,4'-pyrrolidine]-3'-yl]-[(2S,4R)-2-cyclohexyl-4-phenylpiperidin-1-yl]methanone;[(3'S,5R)-2-chlorospiro[7,8-dihydro-6H-quinoline-5,4'-pyrrolidine]-3'-yl]-[(2R,4S)-2-cyclohexyl-4-phenylpiperidin-1-yl]methanone;[(3'S,5R)-2-chlorospiro[7,8-dihydro-6H-quinoline-5,4'-pyrrolidine]-3'-yl]-[(2R,4R)-2-cyclohexyl-4-phenylpiperidin-1-yl]methanone;[(3'S,4R)-1,1-dioxospiro[2,3-dihydrothiochromene-4,4'-pyrrolidine]-3'-yl]-(4-phenylpiperidin-1-yl)methanone;[(3'S,5R)-2-methylspiro[7,8-dihydro-6H-quinoline-5,4'-pyrrolidine]-3'-yl]-(4-phenylpiperidin-1-yl)methanone

[(3'S,5R)-2-chlorospiro[7,8-dihydro-6H-quinoline-5,4'-pyrrolidine]-3'-yl]-[(2S,4R)-2-cyclohexyl-4-phenylpiperidin-1-yl]methanone;[(3'S,5R)-2-chlorospiro[7,8-dihydro-6H-quinoline-5,4'-pyrrolidine]-3'-yl]-[(2R,4S)-2-cyclohexyl-4-phenylpiperidin-1-yl]methanone;[(3'S,5R)-2-chlorospiro[7,8-dihydro-6H-quinoline-5,4'-pyrrolidine]-3'-yl]-[(2R,4R)-2-cyclohexyl-4-phenylpiperidin-1-yl]methanone;[(3'S,4R)-1,1-dioxospiro[2,3-dihydrothiochromene-4,4'-pyrrolidine]-3'-yl]-(4-phenylpiperidin-1-yl)methanone;[(3'S,5R)-2-methylspiro[7,8-dihydro-6H-quinoline-5,4'-pyrrolidine]-3'-yl]-(4-phenylpiperidin-1-yl)methanone (PubChem CID 157265182) has the molecular formula C139H173Cl3N14O7S and a molecular weight of 2290.43 g/mol. Its IUPAC name is [(3'S,5R)-2-chlorospiro[7,8-dihydro-6H-quinoline-5,4'-pyrrolidine]-3'-yl]-[(2S,4R)-2-cyclohexyl-4-phenylpiperidin-1-yl]methanone;[(3'S,5R)-2-chlorospiro[7,8-dihydro-6H-quinoline-5,4'-pyrrolidine]-3'-yl]-[(2R,4S)-2-cyclohexyl-4-phenylpiperidin-1-yl]methanone;[(3'S,5R)-2-chlorospiro[7,8-dihydro-6H-quinoline-5,4'-pyrrolidine]-3'-yl]-[(2R,4R)-2-cyclohexyl-4-phenylpiperidin-1-yl]methanone;[(3'S,4R)-1,1-dioxospiro[2,3-dihydrothiochromene-4,4'-pyrrolidine]-3'-yl]-(4-phenylpiperidin-1-yl)methanone;[(3'S,5R)-2-methylspiro[7,8-dihydro-6H-quinoline-5,4'-pyrrolidine]-3'-yl]-(4-phenylpiperidin-1-yl)methanone.

Molecular Properties

• Compound Name: [(3'S,5R)-2-chlorospiro[7,8-dihydro-6H-quinoline-5,4'-pyrrolidine]-3'-yl]-[(2S,4R)-2-cyclohexyl-4-phenylpiperidin-1-yl]methanone;[(3'S,5R)-2-chlorospiro[7,8-dihydro-6H-quinoline-5,4'-pyrrolidine]-3'-yl]-[(2R,4S)-2-cyclohexyl-4-phenylpiperidin-1-yl]methanone;[(3'S,5R)-2-chlorospiro[7,8-dihydro-6H-quinoline-5,4'-pyrrolidine]-3'-yl]-[(2R,4R)-2-cyclohexyl-4-phenylpiperidin-1-yl]methanone;[(3'S,4R)-1,1-dioxospiro[2,3-dihydrothiochromene-4,4'-pyrrolidine]-3'-yl]-(4-phenylpiperidin-1-yl)methanone;[(3'S,5R)-2-methylspiro[7,8-dihydro-6H-quinoline-5,4'-pyrrolidine]-3'-yl]-(4-phenylpiperidin-1-yl)methanone
• PubChem CID: 157265182
• Molecular Formula: C139H173Cl3N14O7S
• Molecular Weight: 2290.43 g/mol
• Exact Mass: 2287.24
• IUPAC Name: [(3'S,5R)-2-chlorospiro[7,8-dihydro-6H-quinoline-5,4'-pyrrolidine]-3'-yl]-[(2S,4R)-2-cyclohexyl-4-phenylpiperidin-1-yl]methanone;[(3'S,5R)-2-chlorospiro[7,8-dihydro-6H-quinoline-5,4'-pyrrolidine]-3'-yl]-[(2R,4S)-2-cyclohexyl-4-phenylpiperidin-1-yl]methanone;[(3'S,5R)-2-chlorospiro[7,8-dihydro-6H-quinoline-5,4'-pyrrolidine]-3'-yl]-[(2R,4R)-2-cyclohexyl-4-phenylpiperidin-1-yl]methanone;[(3'S,4R)-1,1-dioxospiro[2,3-dihydrothiochromene-4,4'-pyrrolidine]-3'-yl]-(4-phenylpiperidin-1-yl)methanone;[(3'S,5R)-2-methylspiro[7,8-dihydro-6H-quinoline-5,4'-pyrrolidine]-3'-yl]-(4-phenylpiperidin-1-yl)methanone
• SMILES: Cc1ccc2c(n1)CCC[C@]21CNC[C@H]1C(=O)N1CCC(c2ccccc2)CC1.O=C([C@@H]1CNC[C@]12CCCc1nc(Cl)ccc12)N1CC[C@@H](c2ccccc2)C[C@@H]1C1CCCCC1.O=C([C@@H]1CNC[C@]12CCCc1nc(Cl)ccc12)N1CC[C@@H](c2ccccc2)C[C@H]1C1CCCCC1.O=C([C@@H]1CNC[C@]12CCCc1nc(Cl)ccc12)N1CC[C@H](c2ccccc2)C[C@@H]1C1CCCCC1.O=C([C@@H]1CNC[C@]12CCS(=O)(=O)c1ccccc12)N1CCC(c2ccccc2)CC1
• InChI: InChI=1S/3C30H38ClN3O.C25H31N3O.C24H28N2O3S/c3*31-28-14-13-24-26(33-28)12-7-16-30(24)20-32-19-25(30)29(35)34-17-15-23(21-8-3-1-4-9-21)18-27(34)22-10-5-2-6-11-22;1-18-9-10-21-23(27-18)8-5-13-25(21)17-26-16-22(25)24(29)28-14-11-20(12-15-28)19-6-3-2-4-7-19;27-23(26-13-10-19(11-14-26)18-6-2-1-3-7-18)21-16-25-17-24(21)12-15-30(28,29)22-9-5-4-8-20(22)24/h3*1,3-4,8-9,13-14,22-23,25,27,32H,2,5-7,10-12,15-20H2;2-4,6-7,9-10,20,22,26H,5,8,11-17H2,1H3;1-9,19,21,25H,10-17H2/t23-,25+,27+,30+;23-,25+,27-,30+;23-,25-,27+,30-;22-,25-;21-,24-/m11000/s1
• InChIKey: AXXKAQYTRCEGIY-RKLKRRNFSA-N
• XLogP: 23.97
• TPSA: 247.40 Ų
• H-Bond Donors: 5
• H-Bond Acceptors: 16
• Rotatable Bonds: 13
• Heavy Atoms: 164
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	2290.43
LogP ≤ 5	23.97
H-Bond Donors ≤ 5	5
H-Bond Acceptors ≤ 10	16

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': '2-halo_pyridine', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of [(3'S,5R)-2-chlorospiro[7,8-dihydro-6H-quinoline-5,4'-pyrrolidine]-3'-yl]-[(2S,4R)-2-cyclohexyl-4-phenylpiperidin-1-yl]methanone;[(3'S,5R)-2-chlorospiro[7,8-dihydro-6H-quinoline-5,4'-pyrrolidine]-3'-yl]-[(2R,4S)-2-cyclohexyl-4-phenylpiperidin-1-yl]methanone;[(3'S,5R)-2-chlorospiro[7,8-dihydro-6H-quinoline-5,4'-pyrrolidine]-3'-yl]-[(2R,4R)-2-cyclohexyl-4-phenylpiperidin-1-yl]methanone;[(3'S,4R)-1,1-dioxospiro[2,3-dihydrothiochromene-4,4'-pyrrolidine]-3'-yl]-(4-phenylpiperidin-1-yl)methanone;[(3'S,5R)-2-methylspiro[7,8-dihydro-6H-quinoline-5,4'-pyrrolidine]-3'-yl]-(4-phenylpiperidin-1-yl)methanone?

The IUPAC name of [(3'S,5R)-2-chlorospiro[7,8-dihydro-6H-quinoline-5,4'-pyrrolidine]-3'-yl]-[(2S,4R)-2-cyclohexyl-4-phenylpiperidin-1-yl]methanone;[(3'S,5R)-2-chlorospiro[7,8-dihydro-6H-quinoline-5,4'-pyrrolidine]-3'-yl]-[(2R,4S)-2-cyclohexyl-4-phenylpiperidin-1-yl]methanone;[(3'S,5R)-2-chlorospiro[7,8-dihydro-6H-quinoline-5,4'-pyrrolidine]-3'-yl]-[(2R,4R)-2-cyclohexyl-4-phenylpiperidin-1-yl]methanone;[(3'S,4R)-1,1-dioxospiro[2,3-dihydrothiochromene-4,4'-pyrrolidine]-3'-yl]-(4-phenylpiperidin-1-yl)methanone;[(3'S,5R)-2-methylspiro[7,8-dihydro-6H-quinoline-5,4'-pyrrolidine]-3'-yl]-(4-phenylpiperidin-1-yl)methanone (CID 157265182) is [(3'S,5R)-2-chlorospiro[7,8-dihydro-6H-quinoline-5,4'-pyrrolidine]-3'-yl]-[(2S,4R)-2-cyclohexyl-4-phenylpiperidin-1-yl]methanone;[(3'S,5R)-2-chlorospiro[7,8-dihydro-6H-quinoline-5,4'-pyrrolidine]-3'-yl]-[(2R,4S)-2-cyclohexyl-4-phenylpiperidin-1-yl]methanone;[(3'S,5R)-2-chlorospiro[7,8-dihydro-6H-quinoline-5,4'-pyrrolidine]-3'-yl]-[(2R,4R)-2-cyclohexyl-4-phenylpiperidin-1-yl]methanone;[(3'S,4R)-1,1-dioxospiro[2,3-dihydrothiochromene-4,4'-pyrrolidine]-3'-yl]-(4-phenylpiperidin-1-yl)methanone;[(3'S,5R)-2-methylspiro[7,8-dihydro-6H-quinoline-5,4'-pyrrolidine]-3'-yl]-(4-phenylpiperidin-1-yl)methanone.

What is the SMILES notation for [(3'S,5R)-2-chlorospiro[7,8-dihydro-6H-quinoline-5,4'-pyrrolidine]-3'-yl]-[(2S,4R)-2-cyclohexyl-4-phenylpiperidin-1-yl]methanone;[(3'S,5R)-2-chlorospiro[7,8-dihydro-6H-quinoline-5,4'-pyrrolidine]-3'-yl]-[(2R,4S)-2-cyclohexyl-4-phenylpiperidin-1-yl]methanone;[(3'S,5R)-2-chlorospiro[7,8-dihydro-6H-quinoline-5,4'-pyrrolidine]-3'-yl]-[(2R,4R)-2-cyclohexyl-4-phenylpiperidin-1-yl]methanone;[(3'S,4R)-1,1-dioxospiro[2,3-dihydrothiochromene-4,4'-pyrrolidine]-3'-yl]-(4-phenylpiperidin-1-yl)methanone;[(3'S,5R)-2-methylspiro[7,8-dihydro-6H-quinoline-5,4'-pyrrolidine]-3'-yl]-(4-phenylpiperidin-1-yl)methanone?

The canonical SMILES for [(3'S,5R)-2-chlorospiro[7,8-dihydro-6H-quinoline-5,4'-pyrrolidine]-3'-yl]-[(2S,4R)-2-cyclohexyl-4-phenylpiperidin-1-yl]methanone;[(3'S,5R)-2-chlorospiro[7,8-dihydro-6H-quinoline-5,4'-pyrrolidine]-3'-yl]-[(2R,4S)-2-cyclohexyl-4-phenylpiperidin-1-yl]methanone;[(3'S,5R)-2-chlorospiro[7,8-dihydro-6H-quinoline-5,4'-pyrrolidine]-3'-yl]-[(2R,4R)-2-cyclohexyl-4-phenylpiperidin-1-yl]methanone;[(3'S,4R)-1,1-dioxospiro[2,3-dihydrothiochromene-4,4'-pyrrolidine]-3'-yl]-(4-phenylpiperidin-1-yl)methanone;[(3'S,5R)-2-methylspiro[7,8-dihydro-6H-quinoline-5,4'-pyrrolidine]-3'-yl]-(4-phenylpiperidin-1-yl)methanone is Cc1ccc2c(n1)CCC[C@]21CNC[C@H]1C(=O)N1CCC(c2ccccc2)CC1.O=C([C@@H]1CNC[C@]12CCCc1nc(Cl)ccc12)N1CC[C@@H](c2ccccc2)C[C@@H]1C1CCCCC1.O=C([C@@H]1CNC[C@]12CCCc1nc(Cl)ccc12)N1CC[C@@H](c2ccccc2)C[C@H]1C1CCCCC1.O=C([C@@H]1CNC[C@]12CCCc1nc(Cl)ccc12)N1CC[C@H](c2ccccc2)C[C@@H]1C1CCCCC1.O=C([C@@H]1CNC[C@]12CCS(=O)(=O)c1ccccc12)N1CCC(c2ccccc2)CC1.

What is the InChIKey of [(3'S,5R)-2-chlorospiro[7,8-dihydro-6H-quinoline-5,4'-pyrrolidine]-3'-yl]-[(2S,4R)-2-cyclohexyl-4-phenylpiperidin-1-yl]methanone;[(3'S,5R)-2-chlorospiro[7,8-dihydro-6H-quinoline-5,4'-pyrrolidine]-3'-yl]-[(2R,4S)-2-cyclohexyl-4-phenylpiperidin-1-yl]methanone;[(3'S,5R)-2-chlorospiro[7,8-dihydro-6H-quinoline-5,4'-pyrrolidine]-3'-yl]-[(2R,4R)-2-cyclohexyl-4-phenylpiperidin-1-yl]methanone;[(3'S,4R)-1,1-dioxospiro[2,3-dihydrothiochromene-4,4'-pyrrolidine]-3'-yl]-(4-phenylpiperidin-1-yl)methanone;[(3'S,5R)-2-methylspiro[7,8-dihydro-6H-quinoline-5,4'-pyrrolidine]-3'-yl]-(4-phenylpiperidin-1-yl)methanone?

The InChIKey is AXXKAQYTRCEGIY-RKLKRRNFSA-N. The full InChI is InChI=1S/3C30H38ClN3O.C25H31N3O.C24H28N2O3S/c3*31-28-14-13-24-26(33-28)12-7-16-30(24)20-32-19-25(30)29(35)34-17-15-23(21-8-3-1-4-9-21)18-27(34)22-10-5-2-6-11-22;1-18-9-10-21-23(27-18)8-5-13-25(21)17-26-16-22(25)24(29)28-14-11-20(12-15-28)19-6-3-2-4-7-19;27-23(26-13-10-19(11-14-26)18-6-2-1-3-7-18)21-16-25-17-24(21)12-15-30(28,29)22-9-5-4-8-20(22)24/h3*1,3-4,8-9,13-14,22-23,25,27,32H,2,5-7,10-12,15-20H2;2-4,6-7,9-10,20,22,26H,5,8,11-17H2,1H3;1-9,19,21,25H,10-17H2/t23-,25+,27+,30+;23-,25+,27-,30+;23-,25-,27+,30-;22-,25-;21-,24-/m11000/s1.

What are the key properties of [(3'S,5R)-2-chlorospiro[7,8-dihydro-6H-quinoline-5,4'-pyrrolidine]-3'-yl]-[(2S,4R)-2-cyclohexyl-4-phenylpiperidin-1-yl]methanone;[(3'S,5R)-2-chlorospiro[7,8-dihydro-6H-quinoline-5,4'-pyrrolidine]-3'-yl]-[(2R,4S)-2-cyclohexyl-4-phenylpiperidin-1-yl]methanone;[(3'S,5R)-2-chlorospiro[7,8-dihydro-6H-quinoline-5,4'-pyrrolidine]-3'-yl]-[(2R,4R)-2-cyclohexyl-4-phenylpiperidin-1-yl]methanone;[(3'S,4R)-1,1-dioxospiro[2,3-dihydrothiochromene-4,4'-pyrrolidine]-3'-yl]-(4-phenylpiperidin-1-yl)methanone;[(3'S,5R)-2-methylspiro[7,8-dihydro-6H-quinoline-5,4'-pyrrolidine]-3'-yl]-(4-phenylpiperidin-1-yl)methanone?

[(3'S,5R)-2-chlorospiro[7,8-dihydro-6H-quinoline-5,4'-pyrrolidine]-3'-yl]-[(2S,4R)-2-cyclohexyl-4-phenylpiperidin-1-yl]methanone;[(3'S,5R)-2-chlorospiro[7,8-dihydro-6H-quinoline-5,4'-pyrrolidine]-3'-yl]-[(2R,4S)-2-cyclohexyl-4-phenylpiperidin-1-yl]methanone;[(3'S,5R)-2-chlorospiro[7,8-dihydro-6H-quinoline-5,4'-pyrrolidine]-3'-yl]-[(2R,4R)-2-cyclohexyl-4-phenylpiperidin-1-yl]methanone;[(3'S,4R)-1,1-dioxospiro[2,3-dihydrothiochromene-4,4'-pyrrolidine]-3'-yl]-(4-phenylpiperidin-1-yl)methanone;[(3'S,5R)-2-methylspiro[7,8-dihydro-6H-quinoline-5,4'-pyrrolidine]-3'-yl]-(4-phenylpiperidin-1-yl)methanone has a molecular weight of 2290.43 g/mol, XLogP of 23.97, 13 rotatable bonds, 5 hydrogen bond donors, and 16 hydrogen bond acceptors.

Where does this data come from?

All data for [(3'S,5R)-2-chlorospiro[7,8-dihydro-6H-quinoline-5,4'-pyrrolidine]-3'-yl]-[(2S,4R)-2-cyclohexyl-4-phenylpiperidin-1-yl]methanone;[(3'S,5R)-2-chlorospiro[7,8-dihydro-6H-quinoline-5,4'-pyrrolidine]-3'-yl]-[(2R,4S)-2-cyclohexyl-4-phenylpiperidin-1-yl]methanone;[(3'S,5R)-2-chlorospiro[7,8-dihydro-6H-quinoline-5,4'-pyrrolidine]-3'-yl]-[(2R,4R)-2-cyclohexyl-4-phenylpiperidin-1-yl]methanone;[(3'S,4R)-1,1-dioxospiro[2,3-dihydrothiochromene-4,4'-pyrrolidine]-3'-yl]-(4-phenylpiperidin-1-yl)methanone;[(3'S,5R)-2-methylspiro[7,8-dihydro-6H-quinoline-5,4'-pyrrolidine]-3'-yl]-(4-phenylpiperidin-1-yl)methanone is sourced from PubChem (CID 157265182), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).