(5R)-5-[2-[4-[4-(4-ethylpiperazine-1-carbonyl)-2-oxopyrrolidin-1-yl]phenyl]ethynyl]-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;6-[2-fluoro-4-[2-[(4R)-4-[(4-fluoro-5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-2,5-dioxoimidazolidin-4-yl]ethynyl]phenyl]-4,6-diazaspiro[2.4]heptane-5,7-dione;(5R)-5-[2-[3-methoxy-6-[4-(1-methylpiperidin-4-yl)-5-oxo-1H-1,2,4-triazol-3-yl]-2-pyridinyl]ethynyl]-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(3S)-7-[2-[4-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-2,5-dioxoimidazolidin-4-yl]ethynyl]spiro[1,2-dihydroindene-3,5'-imidazolidine]-2',4'-dione

C113H104F2N24O24 — CID 157266436

IUPAC(5R)-5-[2-[4-[4-(4-ethylpiperazine-1-carbonyl)-2-oxopyrrolidin-1-yl]phenyl]ethynyl]-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;6-[2-fluoro-4-[2-[(4R)-4-[(4-fluoro-5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-2,5-dioxoimidazolidin-4-yl]ethynyl]phenyl]-4,6-diazaspiro[2.4]heptane-5,7-dione;(5R)-5-[2-[3-methoxy-6-[4-(1-methylpiperidin-4-yl)-5-oxo-1H-1,2,4-triazol-3-yl]-2-pyridinyl]ethynyl]-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(3S)-7-[2-[4-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-2,5-dioxoimidazolidin-4-yl]ethynyl]spiro[1,2-dihydroindene-3,5'-imidazolidine]-2',4'-dione
SMILESCCN1CCN(C(=O)C2CC(=O)N(c3ccc(C#C[C@]4(CN5Cc6ccc(OC)cc6C5=O)NC(=O)NC4=O)cc3)C2)CC1.COc1ccc2c(c1)C(=O)N(CC1(C#Cc3cccc4c3CC[C@]43NC(=O)NC3=O)NC(=O)NC1=O)C2.COc1ccc2c(c1)C(=O)N(C[C@@]1(C#Cc3nc(-c4n[nH]c(=O)n4C4CCN(C)CC4)ccc3OC)NC(=O)NC1=O)C2.COc1ccc2c(c1F)C(=O)N(C[C@@]1(C#Cc3ccc(N4C(=O)NC5(CC5)C4=O)c(F)c3)NC(=O)NC1=O)C2
InChIInChI=1S/C32H34N6O6.C29H30N8O6.C26H19F2N5O6.C26H21N5O6/c1-3-35-12-14-36(15-13-35)28(40)23-16-27(39)38(19-23)24-7-4-21(5-8-24)10-11-32(30(42)33-31(43)34-32)20-37-18-22-6-9-25(44-2)17-26(22)29(37)41;1-35-12-9-18(10-13-35)37-24(33-34-28(37)41)22-6-7-23(43-3)21(30-22)8-11-29(26(39)31-27(40)32-29)16-36-15-17-4-5-19(42-2)14-20(17)25(36)38;1-39-17-5-3-14-11-32(20(34)18(14)19(17)28)12-26(21(35)29-23(37)30-26)7-6-13-2-4-16(15(27)10-13)33-22(36)25(8-9-25)31-24(33)38;1-37-16-6-5-15-12-31(20(32)18(15)11-16)13-25(21(33)27-23(35)29-25)9-7-14-3-2-4-19-17(14)8-10-26(19)22(34)28-24(36)30-26/h4-9,17,23H,3,12-16,18-20H2,1-2H3,(H2,33,34,42,43);4-7,14,18H,9-10,12-13,15-16H2,1-3H3,(H,34,41)(H2,31,32,39,40);2-5,10H,8-9,11-12H2,1H3,(H,31,38)(H2,29,30,35,37);2-6,11H,8,10,12-13H2,1H3,(H2,27,29,33,35)(H2,28,30,34,36)/t23?,32-;29-;26-;25?,26-/m1110/s1
InChIKeyAYAXTDMAXVALCD-FTKCVFCCSA-N
MW2220.21 g/mol
LogP2.71
Rot. Bonds19

About (5R)-5-[2-[4-[4-(4-ethylpiperazine-1-carbonyl)-2-oxopyrrolidin-1-yl]phenyl]ethynyl]-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;6-[2-fluoro-4-[2-[(4R)-4-[(4-fluoro-5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-2,5-dioxoimidazolidin-4-yl]ethynyl]phenyl]-4,6-diazaspiro[2.4]heptane-5,7-dione;(5R)-5-[2-[3-methoxy-6-[4-(1-methylpiperidin-4-yl)-5-oxo-1H-1,2,4-triazol-3-yl]-2-pyridinyl]ethynyl]-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(3S)-7-[2-[4-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-2,5-dioxoimidazolidin-4-yl]ethynyl]spiro[1,2-dihydroindene-3,5'-imidazolidine]-2',4'-dione

(5R)-5-[2-[4-[4-(4-ethylpiperazine-1-carbonyl)-2-oxopyrrolidin-1-yl]phenyl]ethynyl]-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;6-[2-fluoro-4-[2-[(4R)-4-[(4-fluoro-5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-2,5-dioxoimidazolidin-4-yl]ethynyl]phenyl]-4,6-diazaspiro[2.4]heptane-5,7-dione;(5R)-5-[2-[3-methoxy-6-[4-(1-methylpiperidin-4-yl)-5-oxo-1H-1,2,4-triazol-3-yl]-2-pyridinyl]ethynyl]-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(3S)-7-[2-[4-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-2,5-dioxoimidazolidin-4-yl]ethynyl]spiro[1,2-dihydroindene-3,5'-imidazolidine]-2',4'-dione (PubChem CID 157266436) has the molecular formula C113H104F2N24O24 and a molecular weight of 2220.21 g/mol. Its IUPAC name is (5R)-5-[2-[4-[4-(4-ethylpiperazine-1-carbonyl)-2-oxopyrrolidin-1-yl]phenyl]ethynyl]-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;6-[2-fluoro-4-[2-[(4R)-4-[(4-fluoro-5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-2,5-dioxoimidazolidin-4-yl]ethynyl]phenyl]-4,6-diazaspiro[2.4]heptane-5,7-dione;(5R)-5-[2-[3-methoxy-6-[4-(1-methylpiperidin-4-yl)-5-oxo-1H-1,2,4-triazol-3-yl]-2-pyridinyl]ethynyl]-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(3S)-7-[2-[4-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-2,5-dioxoimidazolidin-4-yl]ethynyl]spiro[1,2-dihydroindene-3,5'-imidazolidine]-2',4'-dione.

Molecular Properties

Compound Name(5R)-5-[2-[4-[4-(4-ethylpiperazine-1-carbonyl)-2-oxopyrrolidin-1-yl]phenyl]ethynyl]-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;6-[2-fluoro-4-[2-[(4R)-4-[(4-fluoro-5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-2,5-dioxoimidazolidin-4-yl]ethynyl]phenyl]-4,6-diazaspiro[2.4]heptane-5,7-dione;(5R)-5-[2-[3-methoxy-6-[4-(1-methylpiperidin-4-yl)-5-oxo-1H-1,2,4-triazol-3-yl]-2-pyridinyl]ethynyl]-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(3S)-7-[2-[4-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-2,5-dioxoimidazolidin-4-yl]ethynyl]spiro[1,2-dihydroindene-3,5'-imidazolidine]-2',4'-dione
PubChem CID157266436
Molecular FormulaC113H104F2N24O24
Molecular Weight2220.21 g/mol
Exact Mass2218.76
IUPAC Name(5R)-5-[2-[4-[4-(4-ethylpiperazine-1-carbonyl)-2-oxopyrrolidin-1-yl]phenyl]ethynyl]-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;6-[2-fluoro-4-[2-[(4R)-4-[(4-fluoro-5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-2,5-dioxoimidazolidin-4-yl]ethynyl]phenyl]-4,6-diazaspiro[2.4]heptane-5,7-dione;(5R)-5-[2-[3-methoxy-6-[4-(1-methylpiperidin-4-yl)-5-oxo-1H-1,2,4-triazol-3-yl]-2-pyridinyl]ethynyl]-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(3S)-7-[2-[4-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-2,5-dioxoimidazolidin-4-yl]ethynyl]spiro[1,2-dihydroindene-3,5'-imidazolidine]-2',4'-dione
SMILESCCN1CCN(C(=O)C2CC(=O)N(c3ccc(C#C[C@]4(CN5Cc6ccc(OC)cc6C5=O)NC(=O)NC4=O)cc3)C2)CC1.COc1ccc2c(c1)C(=O)N(CC1(C#Cc3cccc4c3CC[C@]43NC(=O)NC3=O)NC(=O)NC1=O)C2.COc1ccc2c(c1)C(=O)N(C[C@@]1(C#Cc3nc(-c4n[nH]c(=O)n4C4CCN(C)CC4)ccc3OC)NC(=O)NC1=O)C2.COc1ccc2c(c1F)C(=O)N(C[C@@]1(C#Cc3ccc(N4C(=O)NC5(CC5)C4=O)c(F)c3)NC(=O)NC1=O)C2
InChIInChI=1S/C32H34N6O6.C29H30N8O6.C26H19F2N5O6.C26H21N5O6/c1-3-35-12-14-36(15-13-35)28(40)23-16-27(39)38(19-23)24-7-4-21(5-8-24)10-11-32(30(42)33-31(43)34-32)20-37-18-22-6-9-25(44-2)17-26(22)29(37)41;1-35-12-9-18(10-13-35)37-24(33-34-28(37)41)22-6-7-23(43-3)21(30-22)8-11-29(26(39)31-27(40)32-29)16-36-15-17-4-5-19(42-2)14-20(17)25(36)38;1-39-17-5-3-14-11-32(20(34)18(14)19(17)28)12-26(21(35)29-23(37)30-26)7-6-13-2-4-16(15(27)10-13)33-22(36)25(8-9-25)31-24(33)38;1-37-16-6-5-15-12-31(20(32)18(15)11-16)13-25(21(33)27-23(35)29-25)9-7-14-3-2-4-19-17(14)8-10-26(19)22(34)28-24(36)30-26/h4-9,17,23H,3,12-16,18-20H2,1-2H3,(H2,33,34,42,43);4-7,14,18H,9-10,12-13,15-16H2,1-3H3,(H,34,41)(H2,31,32,39,40);2-5,10H,8-9,11-12H2,1H3,(H,31,38)(H2,29,30,35,37);2-6,11H,8,10,12-13H2,1H3,(H2,27,29,33,35)(H2,28,30,34,36)/t23?,32-;29-;26-;25?,26-/m1110/s1
InChIKeyAYAXTDMAXVALCD-FTKCVFCCSA-N
XLogP2.71
TPSA578.47 Ų
H-Bond Donors12
H-Bond Acceptors29
Rotatable Bonds19
Heavy Atoms163
Complexity—

Lipinski Rule of Five

3 violations

RuleValue
MW ≤ 5002220.21
LogP ≤ 52.71
H-Bond Donors ≤ 512
H-Bond Acceptors ≤ 1029

Computed Properties (RDKit)

Structural Alerts{'alert_name': 'hydantoin', 'substructure': 'N/A'}, {'alert_name': 'triple_bond', 'substructure': 'N/A'}

Analyze (5R)-5-[2-[4-[4-(4-ethylpiperazine-1-carbonyl)-2-oxopyrrolidin-1-yl]phenyl]ethynyl]-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;6-[2-fluoro-4-[2-[(4R)-4-[(4-fluoro-5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-2,5-dioxoimidazolidin-4-yl]ethynyl]phenyl]-4,6-diazaspiro[2.4]heptane-5,7-dione;(5R)-5-[2-[3-methoxy-6-[4-(1-methylpiperidin-4-yl)-5-oxo-1H-1,2,4-triazol-3-yl]-2-pyridinyl]ethynyl]-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(3S)-7-[2-[4-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-2,5-dioxoimidazolidin-4-yl]ethynyl]spiro[1,2-dihydroindene-3,5'-imidazolidine]-2',4'-dione with MolForge

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Frequently Asked Questions

What is the IUPAC name of (5R)-5-[2-[4-[4-(4-ethylpiperazine-1-carbonyl)-2-oxopyrrolidin-1-yl]phenyl]ethynyl]-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;6-[2-fluoro-4-[2-[(4R)-4-[(4-fluoro-5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-2,5-dioxoimidazolidin-4-yl]ethynyl]phenyl]-4,6-diazaspiro[2.4]heptane-5,7-dione;(5R)-5-[2-[3-methoxy-6-[4-(1-methylpiperidin-4-yl)-5-oxo-1H-1,2,4-triazol-3-yl]-2-pyridinyl]ethynyl]-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(3S)-7-[2-[4-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-2,5-dioxoimidazolidin-4-yl]ethynyl]spiro[1,2-dihydroindene-3,5'-imidazolidine]-2',4'-dione?
The IUPAC name of (5R)-5-[2-[4-[4-(4-ethylpiperazine-1-carbonyl)-2-oxopyrrolidin-1-yl]phenyl]ethynyl]-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;6-[2-fluoro-4-[2-[(4R)-4-[(4-fluoro-5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-2,5-dioxoimidazolidin-4-yl]ethynyl]phenyl]-4,6-diazaspiro[2.4]heptane-5,7-dione;(5R)-5-[2-[3-methoxy-6-[4-(1-methylpiperidin-4-yl)-5-oxo-1H-1,2,4-triazol-3-yl]-2-pyridinyl]ethynyl]-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(3S)-7-[2-[4-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-2,5-dioxoimidazolidin-4-yl]ethynyl]spiro[1,2-dihydroindene-3,5'-imidazolidine]-2',4'-dione (CID 157266436) is (5R)-5-[2-[4-[4-(4-ethylpiperazine-1-carbonyl)-2-oxopyrrolidin-1-yl]phenyl]ethynyl]-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;6-[2-fluoro-4-[2-[(4R)-4-[(4-fluoro-5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-2,5-dioxoimidazolidin-4-yl]ethynyl]phenyl]-4,6-diazaspiro[2.4]heptane-5,7-dione;(5R)-5-[2-[3-methoxy-6-[4-(1-methylpiperidin-4-yl)-5-oxo-1H-1,2,4-triazol-3-yl]-2-pyridinyl]ethynyl]-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(3S)-7-[2-[4-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-2,5-dioxoimidazolidin-4-yl]ethynyl]spiro[1,2-dihydroindene-3,5'-imidazolidine]-2',4'-dione.
What is the SMILES notation for (5R)-5-[2-[4-[4-(4-ethylpiperazine-1-carbonyl)-2-oxopyrrolidin-1-yl]phenyl]ethynyl]-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;6-[2-fluoro-4-[2-[(4R)-4-[(4-fluoro-5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-2,5-dioxoimidazolidin-4-yl]ethynyl]phenyl]-4,6-diazaspiro[2.4]heptane-5,7-dione;(5R)-5-[2-[3-methoxy-6-[4-(1-methylpiperidin-4-yl)-5-oxo-1H-1,2,4-triazol-3-yl]-2-pyridinyl]ethynyl]-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(3S)-7-[2-[4-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-2,5-dioxoimidazolidin-4-yl]ethynyl]spiro[1,2-dihydroindene-3,5'-imidazolidine]-2',4'-dione?
The canonical SMILES for (5R)-5-[2-[4-[4-(4-ethylpiperazine-1-carbonyl)-2-oxopyrrolidin-1-yl]phenyl]ethynyl]-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;6-[2-fluoro-4-[2-[(4R)-4-[(4-fluoro-5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-2,5-dioxoimidazolidin-4-yl]ethynyl]phenyl]-4,6-diazaspiro[2.4]heptane-5,7-dione;(5R)-5-[2-[3-methoxy-6-[4-(1-methylpiperidin-4-yl)-5-oxo-1H-1,2,4-triazol-3-yl]-2-pyridinyl]ethynyl]-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(3S)-7-[2-[4-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-2,5-dioxoimidazolidin-4-yl]ethynyl]spiro[1,2-dihydroindene-3,5'-imidazolidine]-2',4'-dione is CCN1CCN(C(=O)C2CC(=O)N(c3ccc(C#C[C@]4(CN5Cc6ccc(OC)cc6C5=O)NC(=O)NC4=O)cc3)C2)CC1.COc1ccc2c(c1)C(=O)N(CC1(C#Cc3cccc4c3CC[C@]43NC(=O)NC3=O)NC(=O)NC1=O)C2.COc1ccc2c(c1)C(=O)N(C[C@@]1(C#Cc3nc(-c4n[nH]c(=O)n4C4CCN(C)CC4)ccc3OC)NC(=O)NC1=O)C2.COc1ccc2c(c1F)C(=O)N(C[C@@]1(C#Cc3ccc(N4C(=O)NC5(CC5)C4=O)c(F)c3)NC(=O)NC1=O)C2.
What is the InChIKey of (5R)-5-[2-[4-[4-(4-ethylpiperazine-1-carbonyl)-2-oxopyrrolidin-1-yl]phenyl]ethynyl]-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;6-[2-fluoro-4-[2-[(4R)-4-[(4-fluoro-5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-2,5-dioxoimidazolidin-4-yl]ethynyl]phenyl]-4,6-diazaspiro[2.4]heptane-5,7-dione;(5R)-5-[2-[3-methoxy-6-[4-(1-methylpiperidin-4-yl)-5-oxo-1H-1,2,4-triazol-3-yl]-2-pyridinyl]ethynyl]-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(3S)-7-[2-[4-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-2,5-dioxoimidazolidin-4-yl]ethynyl]spiro[1,2-dihydroindene-3,5'-imidazolidine]-2',4'-dione?
The InChIKey is AYAXTDMAXVALCD-FTKCVFCCSA-N. The full InChI is InChI=1S/C32H34N6O6.C29H30N8O6.C26H19F2N5O6.C26H21N5O6/c1-3-35-12-14-36(15-13-35)28(40)23-16-27(39)38(19-23)24-7-4-21(5-8-24)10-11-32(30(42)33-31(43)34-32)20-37-18-22-6-9-25(44-2)17-26(22)29(37)41;1-35-12-9-18(10-13-35)37-24(33-34-28(37)41)22-6-7-23(43-3)21(30-22)8-11-29(26(39)31-27(40)32-29)16-36-15-17-4-5-19(42-2)14-20(17)25(36)38;1-39-17-5-3-14-11-32(20(34)18(14)19(17)28)12-26(21(35)29-23(37)30-26)7-6-13-2-4-16(15(27)10-13)33-22(36)25(8-9-25)31-24(33)38;1-37-16-6-5-15-12-31(20(32)18(15)11-16)13-25(21(33)27-23(35)29-25)9-7-14-3-2-4-19-17(14)8-10-26(19)22(34)28-24(36)30-26/h4-9,17,23H,3,12-16,18-20H2,1-2H3,(H2,33,34,42,43);4-7,14,18H,9-10,12-13,15-16H2,1-3H3,(H,34,41)(H2,31,32,39,40);2-5,10H,8-9,11-12H2,1H3,(H,31,38)(H2,29,30,35,37);2-6,11H,8,10,12-13H2,1H3,(H2,27,29,33,35)(H2,28,30,34,36)/t23?,32-;29-;26-;25?,26-/m1110/s1.
What are the key properties of (5R)-5-[2-[4-[4-(4-ethylpiperazine-1-carbonyl)-2-oxopyrrolidin-1-yl]phenyl]ethynyl]-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;6-[2-fluoro-4-[2-[(4R)-4-[(4-fluoro-5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-2,5-dioxoimidazolidin-4-yl]ethynyl]phenyl]-4,6-diazaspiro[2.4]heptane-5,7-dione;(5R)-5-[2-[3-methoxy-6-[4-(1-methylpiperidin-4-yl)-5-oxo-1H-1,2,4-triazol-3-yl]-2-pyridinyl]ethynyl]-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(3S)-7-[2-[4-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-2,5-dioxoimidazolidin-4-yl]ethynyl]spiro[1,2-dihydroindene-3,5'-imidazolidine]-2',4'-dione?
(5R)-5-[2-[4-[4-(4-ethylpiperazine-1-carbonyl)-2-oxopyrrolidin-1-yl]phenyl]ethynyl]-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;6-[2-fluoro-4-[2-[(4R)-4-[(4-fluoro-5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-2,5-dioxoimidazolidin-4-yl]ethynyl]phenyl]-4,6-diazaspiro[2.4]heptane-5,7-dione;(5R)-5-[2-[3-methoxy-6-[4-(1-methylpiperidin-4-yl)-5-oxo-1H-1,2,4-triazol-3-yl]-2-pyridinyl]ethynyl]-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(3S)-7-[2-[4-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-2,5-dioxoimidazolidin-4-yl]ethynyl]spiro[1,2-dihydroindene-3,5'-imidazolidine]-2',4'-dione has a molecular weight of 2220.21 g/mol, XLogP of 2.71, 19 rotatable bonds, 12 hydrogen bond donors, and 29 hydrogen bond acceptors.
Where does this data come from?
All data for (5R)-5-[2-[4-[4-(4-ethylpiperazine-1-carbonyl)-2-oxopyrrolidin-1-yl]phenyl]ethynyl]-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;6-[2-fluoro-4-[2-[(4R)-4-[(4-fluoro-5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-2,5-dioxoimidazolidin-4-yl]ethynyl]phenyl]-4,6-diazaspiro[2.4]heptane-5,7-dione;(5R)-5-[2-[3-methoxy-6-[4-(1-methylpiperidin-4-yl)-5-oxo-1H-1,2,4-triazol-3-yl]-2-pyridinyl]ethynyl]-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(3S)-7-[2-[4-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-2,5-dioxoimidazolidin-4-yl]ethynyl]spiro[1,2-dihydroindene-3,5'-imidazolidine]-2',4'-dione is sourced from PubChem (CID 157266436), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).