1-N-[3-(1-benzothiophen-2-yl)imidazo[1,2-a]pyrazin-8-yl]-3-N,3-N-dimethylbenzene-1,3-diamine;1-N-[3-(6-chloro-3-pyridinyl)imidazo[1,2-a]pyrazin-8-yl]-3-N,3-N-dimethylbenzene-1,3-diamine;4-[8-[3-(dimethylamino)anilino]imidazo[1,2-a]pyrazin-3-yl]benzamide;1-[5-[8-[3-(dimethylamino)anilino]imidazo[1,2-a]pyrazin-3-yl]thiophen-2-yl]ethanone;N-(4-methoxyphenyl)-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-(3-methylsulfonylphenyl)imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-(4-phenoxyphenyl)imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-phenylimidazo[1,2-a]pyrazin-8-amine

C154H139ClN46O6S3 — CID 157268401

About 1-N-[3-(1-benzothiophen-2-yl)imidazo[1,2-a]pyrazin-8-yl]-3-N,3-N-dimethylbenzene-1,3-diamine;1-N-[3-(6-chloro-3-pyridinyl)imidazo[1,2-a]pyrazin-8-yl]-3-N,3-N-dimethylbenzene-1,3-diamine;4-[8-[3-(dimethylamino)anilino]imidazo[1,2-a]pyrazin-3-yl]benzamide;1-[5-[8-[3-(dimethylamino)anilino]imidazo[1,2-a]pyrazin-3-yl]thiophen-2-yl]ethanone;N-(4-methoxyphenyl)-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-(3-methylsulfonylphenyl)imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-(4-phenoxyphenyl)imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-phenylimidazo[1,2-a]pyrazin-8-amine

1-N-[3-(1-benzothiophen-2-yl)imidazo[1,2-a]pyrazin-8-yl]-3-N,3-N-dimethylbenzene-1,3-diamine;1-N-[3-(6-chloro-3-pyridinyl)imidazo[1,2-a]pyrazin-8-yl]-3-N,3-N-dimethylbenzene-1,3-diamine;4-[8-[3-(dimethylamino)anilino]imidazo[1,2-a]pyrazin-3-yl]benzamide;1-[5-[8-[3-(dimethylamino)anilino]imidazo[1,2-a]pyrazin-3-yl]thiophen-2-yl]ethanone;N-(4-methoxyphenyl)-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-(3-methylsulfonylphenyl)imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-(4-phenoxyphenyl)imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-phenylimidazo[1,2-a]pyrazin-8-amine (PubChem CID 157268401) has the molecular formula C154H139ClN46O6S3 and a molecular weight of 2861.78 g/mol. Its IUPAC name is 1-N-[3-(1-benzothiophen-2-yl)imidazo[1,2-a]pyrazin-8-yl]-3-N,3-N-dimethylbenzene-1,3-diamine;1-N-[3-(6-chloro-3-pyridinyl)imidazo[1,2-a]pyrazin-8-yl]-3-N,3-N-dimethylbenzene-1,3-diamine;4-[8-[3-(dimethylamino)anilino]imidazo[1,2-a]pyrazin-3-yl]benzamide;1-[5-[8-[3-(dimethylamino)anilino]imidazo[1,2-a]pyrazin-3-yl]thiophen-2-yl]ethanone;N-(4-methoxyphenyl)-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-(3-methylsulfonylphenyl)imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-(4-phenoxyphenyl)imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-phenylimidazo[1,2-a]pyrazin-8-amine.

Molecular Properties

• Compound Name: 1-N-[3-(1-benzothiophen-2-yl)imidazo[1,2-a]pyrazin-8-yl]-3-N,3-N-dimethylbenzene-1,3-diamine;1-N-[3-(6-chloro-3-pyridinyl)imidazo[1,2-a]pyrazin-8-yl]-3-N,3-N-dimethylbenzene-1,3-diamine;4-[8-[3-(dimethylamino)anilino]imidazo[1,2-a]pyrazin-3-yl]benzamide;1-[5-[8-[3-(dimethylamino)anilino]imidazo[1,2-a]pyrazin-3-yl]thiophen-2-yl]ethanone;N-(4-methoxyphenyl)-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-(3-methylsulfonylphenyl)imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-(4-phenoxyphenyl)imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-phenylimidazo[1,2-a]pyrazin-8-amine
• PubChem CID: 157268401
• Molecular Formula: C154H139ClN46O6S3
• Molecular Weight: 2861.78 g/mol
• Exact Mass: 2859.08
• IUPAC Name: 1-N-[3-(1-benzothiophen-2-yl)imidazo[1,2-a]pyrazin-8-yl]-3-N,3-N-dimethylbenzene-1,3-diamine;1-N-[3-(6-chloro-3-pyridinyl)imidazo[1,2-a]pyrazin-8-yl]-3-N,3-N-dimethylbenzene-1,3-diamine;4-[8-[3-(dimethylamino)anilino]imidazo[1,2-a]pyrazin-3-yl]benzamide;1-[5-[8-[3-(dimethylamino)anilino]imidazo[1,2-a]pyrazin-3-yl]thiophen-2-yl]ethanone;N-(4-methoxyphenyl)-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-(3-methylsulfonylphenyl)imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-(4-phenoxyphenyl)imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-phenylimidazo[1,2-a]pyrazin-8-amine
• SMILES: CC(=O)c1ccc(-c2cnc3c(Nc4cccc(N(C)C)c4)nccn23)s1.CN(C)c1cccc(Nc2nccn3c(-c4cc5ccccc5s4)cnc23)c1.CN(C)c1cccc(Nc2nccn3c(-c4ccc(C(N)=O)cc4)cnc23)c1.CN(C)c1cccc(Nc2nccn3c(-c4ccc(Cl)nc4)cnc23)c1.COc1ccc(Nc2nccn3c(-c4cnn(C)c4)cnc23)cc1.Cn1cc(-c2cnc3c(Nc4ccc(Oc5ccccc5)cc4)nccn23)cn1.Cn1cc(-c2cnc3c(Nc4cccc(S(C)(=O)=O)c4)nccn23)cn1.Cn1cc(-c2cnc3c(Nc4ccccc4)nccn23)cn1
• InChI: InChI=1S/C22H18N6O.C22H19N5S.C21H20N6O.C20H19N5OS.C19H17ClN6.C17H16N6O2S.C17H16N6O.C16H14N6/c1-27-15-16(13-25-27)20-14-24-22-21(23-11-12-28(20)22)26-17-7-9-19(10-8-17)29-18-5-3-2-4-6-18;1-26(2)17-8-5-7-16(13-17)25-21-22-24-14-18(27(22)11-10-23-21)20-12-15-6-3-4-9-19(15)28-20;1-26(2)17-5-3-4-16(12-17)25-20-21-24-13-18(27(21)11-10-23-20)14-6-8-15(9-7-14)19(22)28;1-13(26)17-7-8-18(27-17)16-12-22-20-19(21-9-10-25(16)20)23-14-5-4-6-15(11-14)24(2)3;1-25(2)15-5-3-4-14(10-15)24-18-19-23-12-16(26(19)9-8-21-18)13-6-7-17(20)22-11-13;1-22-11-12(9-20-22)15-10-19-17-16(18-6-7-23(15)17)21-13-4-3-5-14(8-13)26(2,24)25;1-22-11-12(9-20-22)15-10-19-17-16(18-7-8-23(15)17)21-13-3-5-14(24-2)6-4-13;1-21-11-12(9-19-21)14-10-18-16-15(17-7-8-22(14)16)20-13-5-3-2-4-6-13/h2-15H,1H3,(H,23,26);3-14H,1-2H3,(H,23,25);3-13H,1-2H3,(H2,22,28)(H,23,25);4-12H,1-3H3,(H,21,23);3-12H,1-2H3,(H,21,24);3-11H,1-2H3,(H,18,21);3-11H,1-2H3,(H,18,21);2-11H,1H3,(H,17,20)
• InChIKey: AYGHZCYJBHGKGW-UHFFFAOYSA-N
• XLogP: 30.15
• TPSA: 547.65 Ų
• H-Bond Donors: 9
• H-Bond Acceptors: 53
• Rotatable Bonds: 34
• Heavy Atoms: 210
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2861.78
LogP ≤ 5	30.15
H-Bond Donors ≤ 5	9
H-Bond Acceptors ≤ 10	53

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': '2-halo_pyridine', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of 1-N-[3-(1-benzothiophen-2-yl)imidazo[1,2-a]pyrazin-8-yl]-3-N,3-N-dimethylbenzene-1,3-diamine;1-N-[3-(6-chloro-3-pyridinyl)imidazo[1,2-a]pyrazin-8-yl]-3-N,3-N-dimethylbenzene-1,3-diamine;4-[8-[3-(dimethylamino)anilino]imidazo[1,2-a]pyrazin-3-yl]benzamide;1-[5-[8-[3-(dimethylamino)anilino]imidazo[1,2-a]pyrazin-3-yl]thiophen-2-yl]ethanone;N-(4-methoxyphenyl)-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-(3-methylsulfonylphenyl)imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-(4-phenoxyphenyl)imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-phenylimidazo[1,2-a]pyrazin-8-amine?

The IUPAC name of 1-N-[3-(1-benzothiophen-2-yl)imidazo[1,2-a]pyrazin-8-yl]-3-N,3-N-dimethylbenzene-1,3-diamine;1-N-[3-(6-chloro-3-pyridinyl)imidazo[1,2-a]pyrazin-8-yl]-3-N,3-N-dimethylbenzene-1,3-diamine;4-[8-[3-(dimethylamino)anilino]imidazo[1,2-a]pyrazin-3-yl]benzamide;1-[5-[8-[3-(dimethylamino)anilino]imidazo[1,2-a]pyrazin-3-yl]thiophen-2-yl]ethanone;N-(4-methoxyphenyl)-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-(3-methylsulfonylphenyl)imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-(4-phenoxyphenyl)imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-phenylimidazo[1,2-a]pyrazin-8-amine (CID 157268401) is 1-N-[3-(1-benzothiophen-2-yl)imidazo[1,2-a]pyrazin-8-yl]-3-N,3-N-dimethylbenzene-1,3-diamine;1-N-[3-(6-chloro-3-pyridinyl)imidazo[1,2-a]pyrazin-8-yl]-3-N,3-N-dimethylbenzene-1,3-diamine;4-[8-[3-(dimethylamino)anilino]imidazo[1,2-a]pyrazin-3-yl]benzamide;1-[5-[8-[3-(dimethylamino)anilino]imidazo[1,2-a]pyrazin-3-yl]thiophen-2-yl]ethanone;N-(4-methoxyphenyl)-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-(3-methylsulfonylphenyl)imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-(4-phenoxyphenyl)imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-phenylimidazo[1,2-a]pyrazin-8-amine.

What is the SMILES notation for 1-N-[3-(1-benzothiophen-2-yl)imidazo[1,2-a]pyrazin-8-yl]-3-N,3-N-dimethylbenzene-1,3-diamine;1-N-[3-(6-chloro-3-pyridinyl)imidazo[1,2-a]pyrazin-8-yl]-3-N,3-N-dimethylbenzene-1,3-diamine;4-[8-[3-(dimethylamino)anilino]imidazo[1,2-a]pyrazin-3-yl]benzamide;1-[5-[8-[3-(dimethylamino)anilino]imidazo[1,2-a]pyrazin-3-yl]thiophen-2-yl]ethanone;N-(4-methoxyphenyl)-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-(3-methylsulfonylphenyl)imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-(4-phenoxyphenyl)imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-phenylimidazo[1,2-a]pyrazin-8-amine?

The canonical SMILES for 1-N-[3-(1-benzothiophen-2-yl)imidazo[1,2-a]pyrazin-8-yl]-3-N,3-N-dimethylbenzene-1,3-diamine;1-N-[3-(6-chloro-3-pyridinyl)imidazo[1,2-a]pyrazin-8-yl]-3-N,3-N-dimethylbenzene-1,3-diamine;4-[8-[3-(dimethylamino)anilino]imidazo[1,2-a]pyrazin-3-yl]benzamide;1-[5-[8-[3-(dimethylamino)anilino]imidazo[1,2-a]pyrazin-3-yl]thiophen-2-yl]ethanone;N-(4-methoxyphenyl)-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-(3-methylsulfonylphenyl)imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-(4-phenoxyphenyl)imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-phenylimidazo[1,2-a]pyrazin-8-amine is CC(=O)c1ccc(-c2cnc3c(Nc4cccc(N(C)C)c4)nccn23)s1.CN(C)c1cccc(Nc2nccn3c(-c4cc5ccccc5s4)cnc23)c1.CN(C)c1cccc(Nc2nccn3c(-c4ccc(C(N)=O)cc4)cnc23)c1.CN(C)c1cccc(Nc2nccn3c(-c4ccc(Cl)nc4)cnc23)c1.COc1ccc(Nc2nccn3c(-c4cnn(C)c4)cnc23)cc1.Cn1cc(-c2cnc3c(Nc4ccc(Oc5ccccc5)cc4)nccn23)cn1.Cn1cc(-c2cnc3c(Nc4cccc(S(C)(=O)=O)c4)nccn23)cn1.Cn1cc(-c2cnc3c(Nc4ccccc4)nccn23)cn1.

What is the InChIKey of 1-N-[3-(1-benzothiophen-2-yl)imidazo[1,2-a]pyrazin-8-yl]-3-N,3-N-dimethylbenzene-1,3-diamine;1-N-[3-(6-chloro-3-pyridinyl)imidazo[1,2-a]pyrazin-8-yl]-3-N,3-N-dimethylbenzene-1,3-diamine;4-[8-[3-(dimethylamino)anilino]imidazo[1,2-a]pyrazin-3-yl]benzamide;1-[5-[8-[3-(dimethylamino)anilino]imidazo[1,2-a]pyrazin-3-yl]thiophen-2-yl]ethanone;N-(4-methoxyphenyl)-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-(3-methylsulfonylphenyl)imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-(4-phenoxyphenyl)imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-phenylimidazo[1,2-a]pyrazin-8-amine?

The InChIKey is AYGHZCYJBHGKGW-UHFFFAOYSA-N. The full InChI is InChI=1S/C22H18N6O.C22H19N5S.C21H20N6O.C20H19N5OS.C19H17ClN6.C17H16N6O2S.C17H16N6O.C16H14N6/c1-27-15-16(13-25-27)20-14-24-22-21(23-11-12-28(20)22)26-17-7-9-19(10-8-17)29-18-5-3-2-4-6-18;1-26(2)17-8-5-7-16(13-17)25-21-22-24-14-18(27(22)11-10-23-21)20-12-15-6-3-4-9-19(15)28-20;1-26(2)17-5-3-4-16(12-17)25-20-21-24-13-18(27(21)11-10-23-20)14-6-8-15(9-7-14)19(22)28;1-13(26)17-7-8-18(27-17)16-12-22-20-19(21-9-10-25(16)20)23-14-5-4-6-15(11-14)24(2)3;1-25(2)15-5-3-4-14(10-15)24-18-19-23-12-16(26(19)9-8-21-18)13-6-7-17(20)22-11-13;1-22-11-12(9-20-22)15-10-19-17-16(18-6-7-23(15)17)21-13-4-3-5-14(8-13)26(2,24)25;1-22-11-12(9-20-22)15-10-19-17-16(18-7-8-23(15)17)21-13-3-5-14(24-2)6-4-13;1-21-11-12(9-19-21)14-10-18-16-15(17-7-8-22(14)16)20-13-5-3-2-4-6-13/h2-15H,1H3,(H,23,26);3-14H,1-2H3,(H,23,25);3-13H,1-2H3,(H2,22,28)(H,23,25);4-12H,1-3H3,(H,21,23);3-12H,1-2H3,(H,21,24);3-11H,1-2H3,(H,18,21);3-11H,1-2H3,(H,18,21);2-11H,1H3,(H,17,20).

What are the key properties of 1-N-[3-(1-benzothiophen-2-yl)imidazo[1,2-a]pyrazin-8-yl]-3-N,3-N-dimethylbenzene-1,3-diamine;1-N-[3-(6-chloro-3-pyridinyl)imidazo[1,2-a]pyrazin-8-yl]-3-N,3-N-dimethylbenzene-1,3-diamine;4-[8-[3-(dimethylamino)anilino]imidazo[1,2-a]pyrazin-3-yl]benzamide;1-[5-[8-[3-(dimethylamino)anilino]imidazo[1,2-a]pyrazin-3-yl]thiophen-2-yl]ethanone;N-(4-methoxyphenyl)-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-(3-methylsulfonylphenyl)imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-(4-phenoxyphenyl)imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-phenylimidazo[1,2-a]pyrazin-8-amine?

1-N-[3-(1-benzothiophen-2-yl)imidazo[1,2-a]pyrazin-8-yl]-3-N,3-N-dimethylbenzene-1,3-diamine;1-N-[3-(6-chloro-3-pyridinyl)imidazo[1,2-a]pyrazin-8-yl]-3-N,3-N-dimethylbenzene-1,3-diamine;4-[8-[3-(dimethylamino)anilino]imidazo[1,2-a]pyrazin-3-yl]benzamide;1-[5-[8-[3-(dimethylamino)anilino]imidazo[1,2-a]pyrazin-3-yl]thiophen-2-yl]ethanone;N-(4-methoxyphenyl)-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-(3-methylsulfonylphenyl)imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-(4-phenoxyphenyl)imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-phenylimidazo[1,2-a]pyrazin-8-amine has a molecular weight of 2861.78 g/mol, XLogP of 30.15, 34 rotatable bonds, 9 hydrogen bond donors, and 53 hydrogen bond acceptors.

Where does this data come from?

All data for 1-N-[3-(1-benzothiophen-2-yl)imidazo[1,2-a]pyrazin-8-yl]-3-N,3-N-dimethylbenzene-1,3-diamine;1-N-[3-(6-chloro-3-pyridinyl)imidazo[1,2-a]pyrazin-8-yl]-3-N,3-N-dimethylbenzene-1,3-diamine;4-[8-[3-(dimethylamino)anilino]imidazo[1,2-a]pyrazin-3-yl]benzamide;1-[5-[8-[3-(dimethylamino)anilino]imidazo[1,2-a]pyrazin-3-yl]thiophen-2-yl]ethanone;N-(4-methoxyphenyl)-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-(3-methylsulfonylphenyl)imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-(4-phenoxyphenyl)imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-phenylimidazo[1,2-a]pyrazin-8-amine is sourced from PubChem (CID 157268401), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).