2-(2-cyanopropan-2-yl)-N-[3-[6-ethoxy-5-[(3R)-3-methylmorpholin-4-yl]pyridazin-3-yl]-4-methylphenyl]pyridine-4-carboxamide;2-(2-cyanopropan-2-yl)-N-[5-[6-ethoxy-5-[(3R)-3-methylmorpholin-4-yl]pyridazin-3-yl]-6-methyl-3-pyridinyl]pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[5-(6-ethoxy-5-morpholin-4-ylpyridazin-3-yl)-6-methyl-3-pyridinyl]pyridine-4-carboxamide;3-(difluoromethyl)-N-[5-(6-ethoxy-5-morpholin-4-ylpyridazin-3-yl)-6-methyl-3-pyridinyl]benzamide;N-[5-[6-ethoxy-5-[(3R)-3-methylmorpholin-4-yl]pyridazin-3-yl]-6-methyl-3-pyridinyl]-3-(trifluoromethyl)benzamide;N-[5-(6-ethoxy-5-morpholin-4-ylpyridazin-3-yl)-6-methyl-3-pyridinyl]-3-methylsulfonylbenzamide;N-[5-(6-ethoxy-5-morpholin-4-ylpyridazin-3-yl)-6-methyl-3-pyridinyl]-2-propan-2-ylpyridine-4-carboxamide;N-[5-[6-ethoxy-5-[2-(3H-pyrrol-2-yl)morpholin-4-yl]pyridazin-3-yl]-6-methyl-3-pyridinyl]-3-(trifluoromethyl)benzamide

C205H224F10N46O26S — CID 157268806

IUPAC2-(2-cyanopropan-2-yl)-N-[3-[6-ethoxy-5-[(3R)-3-methylmorpholin-4-yl]pyridazin-3-yl]-4-methylphenyl]pyridine-4-carboxamide;2-(2-cyanopropan-2-yl)-N-[5-[6-ethoxy-5-[(3R)-3-methylmorpholin-4-yl]pyridazin-3-yl]-6-methyl-3-pyridinyl]pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[5-(6-ethoxy-5-morpholin-4-ylpyridazin-3-yl)-6-methyl-3-pyridinyl]pyridine-4-carboxamide;3-(difluoromethyl)-N-[5-(6-ethoxy-5-morpholin-4-ylpyridazin-3-yl)-6-methyl-3-pyridinyl]benzamide;N-[5-[6-ethoxy-5-[(3R)-3-methylmorpholin-4-yl]pyridazin-3-yl]-6-methyl-3-pyridinyl]-3-(trifluoromethyl)benzamide;N-[5-(6-ethoxy-5-morpholin-4-ylpyridazin-3-yl)-6-methyl-3-pyridinyl]-3-methylsulfonylbenzamide;N-[5-(6-ethoxy-5-morpholin-4-ylpyridazin-3-yl)-6-methyl-3-pyridinyl]-2-propan-2-ylpyridine-4-carboxamide;N-[5-[6-ethoxy-5-[2-(3H-pyrrol-2-yl)morpholin-4-yl]pyridazin-3-yl]-6-methyl-3-pyridinyl]-3-(trifluoromethyl)benzamide
SMILESCCOc1nnc(-c2cc(NC(=O)c3cccc(C(F)(F)F)c3)cnc2C)cc1N1CCOC(C2=NC=CC2)C1.CCOc1nnc(-c2cc(NC(=O)c3cccc(C(F)(F)F)c3)cnc2C)cc1N1CCOC[C@H]1C.CCOc1nnc(-c2cc(NC(=O)c3cccc(C(F)F)c3)cnc2C)cc1N1CCOCC1.CCOc1nnc(-c2cc(NC(=O)c3cccc(S(C)(=O)=O)c3)cnc2C)cc1N1CCOCC1.CCOc1nnc(-c2cc(NC(=O)c3ccnc(C(C)(C)C#N)c3)ccc2C)cc1N1CCOC[C@H]1C.CCOc1nnc(-c2cc(NC(=O)c3ccnc(C(C)(C)C#N)c3)cnc2C)cc1N1CCOC[C@H]1C.CCOc1nnc(-c2cc(NC(=O)c3ccnc(C(C)(F)F)c3)cnc2C)cc1N1CCOCC1.CCOc1nnc(-c2cc(NC(=O)c3ccnc(C(C)C)c3)cnc2C)cc1N1CCOCC1
InChIInChI=1S/C28H27F3N6O3.C28H32N6O3.C27H31N7O3.C25H26F3N5O3.C25H30N6O3.C24H26F2N6O3.C24H25F2N5O3.C24H27N5O5S/c1-3-39-27-24(37-10-11-40-25(16-37)22-8-5-9-32-22)14-23(35-36-27)21-13-20(15-33-17(21)2)34-26(38)18-6-4-7-19(12-18)28(29,30)31;1-6-37-27-24(34-11-12-36-16-19(34)3)15-23(32-33-27)22-14-21(8-7-18(22)2)31-26(35)20-9-10-30-25(13-20)28(4,5)17-29;1-6-37-26-23(34-9-10-36-15-17(34)2)13-22(32-33-26)21-12-20(14-30-18(21)3)31-25(35)19-7-8-29-24(11-19)27(4,5)16-28;1-4-36-24-22(33-8-9-35-14-15(33)2)12-21(31-32-24)20-11-19(13-29-16(20)3)30-23(34)17-6-5-7-18(10-17)25(26,27)28;1-5-34-25-23(31-8-10-33-11-9-31)14-22(29-30-25)20-13-19(15-27-17(20)4)28-24(32)18-6-7-26-21(12-18)16(2)3;1-4-35-23-20(32-7-9-34-10-8-32)13-19(30-31-23)18-12-17(14-28-15(18)2)29-22(33)16-5-6-27-21(11-16)24(3,25)26;1-3-34-24-21(31-7-9-33-10-8-31)13-20(29-30-24)19-12-18(14-27-15(19)2)28-23(32)17-6-4-5-16(11-17)22(25)26;1-4-34-24-22(29-8-10-33-11-9-29)14-21(27-28-24)20-13-18(15-25-16(20)2)26-23(30)17-6-5-7-19(12-17)35(3,31)32/h4-7,9,12-15,25H,3,8,10-11,16H2,1-2H3,(H,34,38);7-10,13-15,19H,6,11-12,16H2,1-5H3,(H,31,35);7-8,11-14,17H,6,9-10,15H2,1-5H3,(H,31,35);5-7,10-13,15H,4,8-9,14H2,1-3H3,(H,30,34);6-7,12-16H,5,8-11H2,1-4H3,(H,28,32);5-6,11-14H,4,7-10H2,1-3H3,(H,29,33);4-6,11-14,22H,3,7-10H2,1-2H3,(H,28,32);5-7,12-15H,4,8-11H2,1-3H3,(H,26,30)/t;19-;17-;15-;;;;/m.111..../s1
InChIKeyAYHLLDDVBGQHQA-JEFPUCOLSA-N
MW3970.39 g/mol
LogP32.97
Rot. Bonds55

About 2-(2-cyanopropan-2-yl)-N-[3-[6-ethoxy-5-[(3R)-3-methylmorpholin-4-yl]pyridazin-3-yl]-4-methylphenyl]pyridine-4-carboxamide;2-(2-cyanopropan-2-yl)-N-[5-[6-ethoxy-5-[(3R)-3-methylmorpholin-4-yl]pyridazin-3-yl]-6-methyl-3-pyridinyl]pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[5-(6-ethoxy-5-morpholin-4-ylpyridazin-3-yl)-6-methyl-3-pyridinyl]pyridine-4-carboxamide;3-(difluoromethyl)-N-[5-(6-ethoxy-5-morpholin-4-ylpyridazin-3-yl)-6-methyl-3-pyridinyl]benzamide;N-[5-[6-ethoxy-5-[(3R)-3-methylmorpholin-4-yl]pyridazin-3-yl]-6-methyl-3-pyridinyl]-3-(trifluoromethyl)benzamide;N-[5-(6-ethoxy-5-morpholin-4-ylpyridazin-3-yl)-6-methyl-3-pyridinyl]-3-methylsulfonylbenzamide;N-[5-(6-ethoxy-5-morpholin-4-ylpyridazin-3-yl)-6-methyl-3-pyridinyl]-2-propan-2-ylpyridine-4-carboxamide;N-[5-[6-ethoxy-5-[2-(3H-pyrrol-2-yl)morpholin-4-yl]pyridazin-3-yl]-6-methyl-3-pyridinyl]-3-(trifluoromethyl)benzamide

2-(2-cyanopropan-2-yl)-N-[3-[6-ethoxy-5-[(3R)-3-methylmorpholin-4-yl]pyridazin-3-yl]-4-methylphenyl]pyridine-4-carboxamide;2-(2-cyanopropan-2-yl)-N-[5-[6-ethoxy-5-[(3R)-3-methylmorpholin-4-yl]pyridazin-3-yl]-6-methyl-3-pyridinyl]pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[5-(6-ethoxy-5-morpholin-4-ylpyridazin-3-yl)-6-methyl-3-pyridinyl]pyridine-4-carboxamide;3-(difluoromethyl)-N-[5-(6-ethoxy-5-morpholin-4-ylpyridazin-3-yl)-6-methyl-3-pyridinyl]benzamide;N-[5-[6-ethoxy-5-[(3R)-3-methylmorpholin-4-yl]pyridazin-3-yl]-6-methyl-3-pyridinyl]-3-(trifluoromethyl)benzamide;N-[5-(6-ethoxy-5-morpholin-4-ylpyridazin-3-yl)-6-methyl-3-pyridinyl]-3-methylsulfonylbenzamide;N-[5-(6-ethoxy-5-morpholin-4-ylpyridazin-3-yl)-6-methyl-3-pyridinyl]-2-propan-2-ylpyridine-4-carboxamide;N-[5-[6-ethoxy-5-[2-(3H-pyrrol-2-yl)morpholin-4-yl]pyridazin-3-yl]-6-methyl-3-pyridinyl]-3-(trifluoromethyl)benzamide (PubChem CID 157268806) has the molecular formula C205H224F10N46O26S and a molecular weight of 3970.39 g/mol. Its IUPAC name is 2-(2-cyanopropan-2-yl)-N-[3-[6-ethoxy-5-[(3R)-3-methylmorpholin-4-yl]pyridazin-3-yl]-4-methylphenyl]pyridine-4-carboxamide;2-(2-cyanopropan-2-yl)-N-[5-[6-ethoxy-5-[(3R)-3-methylmorpholin-4-yl]pyridazin-3-yl]-6-methyl-3-pyridinyl]pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[5-(6-ethoxy-5-morpholin-4-ylpyridazin-3-yl)-6-methyl-3-pyridinyl]pyridine-4-carboxamide;3-(difluoromethyl)-N-[5-(6-ethoxy-5-morpholin-4-ylpyridazin-3-yl)-6-methyl-3-pyridinyl]benzamide;N-[5-[6-ethoxy-5-[(3R)-3-methylmorpholin-4-yl]pyridazin-3-yl]-6-methyl-3-pyridinyl]-3-(trifluoromethyl)benzamide;N-[5-(6-ethoxy-5-morpholin-4-ylpyridazin-3-yl)-6-methyl-3-pyridinyl]-3-methylsulfonylbenzamide;N-[5-(6-ethoxy-5-morpholin-4-ylpyridazin-3-yl)-6-methyl-3-pyridinyl]-2-propan-2-ylpyridine-4-carboxamide;N-[5-[6-ethoxy-5-[2-(3H-pyrrol-2-yl)morpholin-4-yl]pyridazin-3-yl]-6-methyl-3-pyridinyl]-3-(trifluoromethyl)benzamide.

Molecular Properties

Compound Name2-(2-cyanopropan-2-yl)-N-[3-[6-ethoxy-5-[(3R)-3-methylmorpholin-4-yl]pyridazin-3-yl]-4-methylphenyl]pyridine-4-carboxamide;2-(2-cyanopropan-2-yl)-N-[5-[6-ethoxy-5-[(3R)-3-methylmorpholin-4-yl]pyridazin-3-yl]-6-methyl-3-pyridinyl]pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[5-(6-ethoxy-5-morpholin-4-ylpyridazin-3-yl)-6-methyl-3-pyridinyl]pyridine-4-carboxamide;3-(difluoromethyl)-N-[5-(6-ethoxy-5-morpholin-4-ylpyridazin-3-yl)-6-methyl-3-pyridinyl]benzamide;N-[5-[6-ethoxy-5-[(3R)-3-methylmorpholin-4-yl]pyridazin-3-yl]-6-methyl-3-pyridinyl]-3-(trifluoromethyl)benzamide;N-[5-(6-ethoxy-5-morpholin-4-ylpyridazin-3-yl)-6-methyl-3-pyridinyl]-3-methylsulfonylbenzamide;N-[5-(6-ethoxy-5-morpholin-4-ylpyridazin-3-yl)-6-methyl-3-pyridinyl]-2-propan-2-ylpyridine-4-carboxamide;N-[5-[6-ethoxy-5-[2-(3H-pyrrol-2-yl)morpholin-4-yl]pyridazin-3-yl]-6-methyl-3-pyridinyl]-3-(trifluoromethyl)benzamide
PubChem CID157268806
Molecular FormulaC205H224F10N46O26S
Molecular Weight3970.39 g/mol
Exact Mass3967.72
IUPAC Name2-(2-cyanopropan-2-yl)-N-[3-[6-ethoxy-5-[(3R)-3-methylmorpholin-4-yl]pyridazin-3-yl]-4-methylphenyl]pyridine-4-carboxamide;2-(2-cyanopropan-2-yl)-N-[5-[6-ethoxy-5-[(3R)-3-methylmorpholin-4-yl]pyridazin-3-yl]-6-methyl-3-pyridinyl]pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[5-(6-ethoxy-5-morpholin-4-ylpyridazin-3-yl)-6-methyl-3-pyridinyl]pyridine-4-carboxamide;3-(difluoromethyl)-N-[5-(6-ethoxy-5-morpholin-4-ylpyridazin-3-yl)-6-methyl-3-pyridinyl]benzamide;N-[5-[6-ethoxy-5-[(3R)-3-methylmorpholin-4-yl]pyridazin-3-yl]-6-methyl-3-pyridinyl]-3-(trifluoromethyl)benzamide;N-[5-(6-ethoxy-5-morpholin-4-ylpyridazin-3-yl)-6-methyl-3-pyridinyl]-3-methylsulfonylbenzamide;N-[5-(6-ethoxy-5-morpholin-4-ylpyridazin-3-yl)-6-methyl-3-pyridinyl]-2-propan-2-ylpyridine-4-carboxamide;N-[5-[6-ethoxy-5-[2-(3H-pyrrol-2-yl)morpholin-4-yl]pyridazin-3-yl]-6-methyl-3-pyridinyl]-3-(trifluoromethyl)benzamide
SMILESCCOc1nnc(-c2cc(NC(=O)c3cccc(C(F)(F)F)c3)cnc2C)cc1N1CCOC(C2=NC=CC2)C1.CCOc1nnc(-c2cc(NC(=O)c3cccc(C(F)(F)F)c3)cnc2C)cc1N1CCOC[C@H]1C.CCOc1nnc(-c2cc(NC(=O)c3cccc(C(F)F)c3)cnc2C)cc1N1CCOCC1.CCOc1nnc(-c2cc(NC(=O)c3cccc(S(C)(=O)=O)c3)cnc2C)cc1N1CCOCC1.CCOc1nnc(-c2cc(NC(=O)c3ccnc(C(C)(C)C#N)c3)ccc2C)cc1N1CCOC[C@H]1C.CCOc1nnc(-c2cc(NC(=O)c3ccnc(C(C)(C)C#N)c3)cnc2C)cc1N1CCOC[C@H]1C.CCOc1nnc(-c2cc(NC(=O)c3ccnc(C(C)(F)F)c3)cnc2C)cc1N1CCOCC1.CCOc1nnc(-c2cc(NC(=O)c3ccnc(C(C)C)c3)cnc2C)cc1N1CCOCC1
InChIInChI=1S/C28H27F3N6O3.C28H32N6O3.C27H31N7O3.C25H26F3N5O3.C25H30N6O3.C24H26F2N6O3.C24H25F2N5O3.C24H27N5O5S/c1-3-39-27-24(37-10-11-40-25(16-37)22-8-5-9-32-22)14-23(35-36-27)21-13-20(15-33-17(21)2)34-26(38)18-6-4-7-19(12-18)28(29,30)31;1-6-37-27-24(34-11-12-36-16-19(34)3)15-23(32-33-27)22-14-21(8-7-18(22)2)31-26(35)20-9-10-30-25(13-20)28(4,5)17-29;1-6-37-26-23(34-9-10-36-15-17(34)2)13-22(32-33-26)21-12-20(14-30-18(21)3)31-25(35)19-7-8-29-24(11-19)27(4,5)16-28;1-4-36-24-22(33-8-9-35-14-15(33)2)12-21(31-32-24)20-11-19(13-29-16(20)3)30-23(34)17-6-5-7-18(10-17)25(26,27)28;1-5-34-25-23(31-8-10-33-11-9-31)14-22(29-30-25)20-13-19(15-27-17(20)4)28-24(32)18-6-7-26-21(12-18)16(2)3;1-4-35-23-20(32-7-9-34-10-8-32)13-19(30-31-23)18-12-17(14-28-15(18)2)29-22(33)16-5-6-27-21(11-16)24(3,25)26;1-3-34-24-21(31-7-9-33-10-8-31)13-20(29-30-24)19-12-18(14-27-15(19)2)28-23(32)17-6-4-5-16(11-17)22(25)26;1-4-34-24-22(29-8-10-33-11-9-29)14-21(27-28-24)20-13-18(15-25-16(20)2)26-23(30)17-6-5-7-19(12-17)35(3,31)32/h4-7,9,12-15,25H,3,8,10-11,16H2,1-2H3,(H,34,38);7-10,13-15,19H,6,11-12,16H2,1-5H3,(H,31,35);7-8,11-14,17H,6,9-10,15H2,1-5H3,(H,31,35);5-7,10-13,15H,4,8-9,14H2,1-3H3,(H,30,34);6-7,12-16H,5,8-11H2,1-4H3,(H,28,32);5-6,11-14H,4,7-10H2,1-3H3,(H,29,33);4-6,11-14,22H,3,7-10H2,1-2H3,(H,28,32);5-7,12-15H,4,8-11H2,1-3H3,(H,26,30)/t;19-;17-;15-;;;;/m.111..../s1
InChIKeyAYHLLDDVBGQHQA-JEFPUCOLSA-N
XLogP32.97
TPSA848.51 Ų
H-Bond Donors8
H-Bond Acceptors64
Rotatable Bonds55
Heavy Atoms288
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5003970.39
LogP ≤ 532.97
H-Bond Donors ≤ 58
H-Bond Acceptors ≤ 1064

Analyze 2-(2-cyanopropan-2-yl)-N-[3-[6-ethoxy-5-[(3R)-3-methylmorpholin-4-yl]pyridazin-3-yl]-4-methylphenyl]pyridine-4-carboxamide;2-(2-cyanopropan-2-yl)-N-[5-[6-ethoxy-5-[(3R)-3-methylmorpholin-4-yl]pyridazin-3-yl]-6-methyl-3-pyridinyl]pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[5-(6-ethoxy-5-morpholin-4-ylpyridazin-3-yl)-6-methyl-3-pyridinyl]pyridine-4-carboxamide;3-(difluoromethyl)-N-[5-(6-ethoxy-5-morpholin-4-ylpyridazin-3-yl)-6-methyl-3-pyridinyl]benzamide;N-[5-[6-ethoxy-5-[(3R)-3-methylmorpholin-4-yl]pyridazin-3-yl]-6-methyl-3-pyridinyl]-3-(trifluoromethyl)benzamide;N-[5-(6-ethoxy-5-morpholin-4-ylpyridazin-3-yl)-6-methyl-3-pyridinyl]-3-methylsulfonylbenzamide;N-[5-(6-ethoxy-5-morpholin-4-ylpyridazin-3-yl)-6-methyl-3-pyridinyl]-2-propan-2-ylpyridine-4-carboxamide;N-[5-[6-ethoxy-5-[2-(3H-pyrrol-2-yl)morpholin-4-yl]pyridazin-3-yl]-6-methyl-3-pyridinyl]-3-(trifluoromethyl)benzamide with MolForge

Explore ADMET properties, 3D molecular structure, drug-likeness score, and discover similar compounds using our AI-powered platform.

Launch Full Analysis

Related Compounds

2-(1,1-difluoroethyl)-N-[3-[(9S,10S)-9-[4-[4-[[3-[(9R,10R)-9-ethyl-8,12-dioxa-1,5,6-triazatricyclo[8.4.0.02,7]tetradeca-2,4,6-trien-4-yl]-4-methylphenyl]carbamoyl]pyridin-2-yl]-4,4-difluorobutan-2-yl]-8,12-dioxa-1,5,6-triazatricyclo[8.4.0.02,7]tetradeca-2,4,6-trien-4-yl]-4-methylphenyl]pyridine-4-carboxamide
CID 129272086
N-[3-(6-ethoxy-5-morpholin-4-ylpyridin-3-yl)-4-methylphenyl]-5-[2-[[[3-[[3-(6-ethoxy-5-morpholin-4-ylpyridin-3-yl)-4-methylphenyl]carbamoyl]phenyl]-methyl-oxo-lambda6-sulfanylidene]amino]ethoxy]-2-(trifluoromethyl)pyridine-4-carboxamide
CID 130425579
2-(2-cyanopropan-2-yl)-N-[3-[5-[(3R)-2-[2-[6-[5-[[2-(2-cyanopropan-2-yl)pyridine-4-carbonyl]amino]-2-methyl-3-pyridinyl]-4-[(3R)-3-methyl-2-[2-[4-[(3R)-3-methylmorpholin-4-yl]-6-[2-methyl-5-[[3-(trifluoromethyl)benzoyl]amino]-3-pyridinyl]pyridazin-3-yl]oxyethyl]morpholin-4-yl]pyridazin-3-yl]oxyethyl]-3-methylmorpholin-4-yl]-6-ethoxypyridazin-3-yl]-4-methylphenyl]pyridine-4-carboxamide
CID 130425581
2-cyclopropyl-N-[3-[6-[2-[4-[3-ethoxy-6-[5-[[2-(2-fluoropropan-2-yl)pyridine-4-carbonyl]amino]-2-methylphenyl]pyridazin-4-yl]morpholin-2-yl]ethoxy]-5-morpholin-4-ylpyridazin-3-yl]-4-methylphenyl]pyridine-4-carboxamide
CID 130425657
6-(2-cyanopropan-2-yl)-N-[3-[6-ethoxy-5-[2-[2-[6-[2-methyl-5-[[2-(trifluoromethyl)pyridine-4-carbonyl]amino]phenyl]-4-morpholin-4-ylpyridazin-3-yl]oxyethyl]morpholin-4-yl]pyridazin-3-yl]-4-methylphenyl]pyridazine-4-carboxamide
CID 130425658
2-(2-cyanopropan-2-yl)-N-[3-[6-[1-[4-[6-[5-[[2-(1,1-difluoroethyl)pyridine-4-carbonyl]amino]-2-methylphenyl]-3-(2-methoxyethoxy)pyridazin-4-yl]morpholin-2-yl]propan-2-yloxy]-5-[2-[2-[6-[5-[[2-(2-fluoropropan-2-yl)pyridine-4-carbonyl]amino]-2-methylphenyl]-4-morpholin-4-ylpyridazin-3-yl]oxypropyl]morpholin-4-yl]pyridazin-3-yl]-4-methylphenyl]pyridine-4-carboxamide
CID 130425721
2-(1,1-difluoroethyl)-N-[3-[6-[2-[4-[3-ethoxy-6-[2-methyl-5-[(3-methylsulfonylbenzoyl)amino]phenyl]pyridazin-4-yl]morpholin-2-yl]ethoxy]-5-morpholin-4-ylpyridazin-3-yl]-4-methylphenyl]pyridine-4-carboxamide
CID 130425814
N-[3-[6-[2-[4-[6-[5-[[3-(difluoromethyl)benzoyl]amino]-2-methylphenyl]-3-ethoxypyridazin-4-yl]morpholin-2-yl]ethoxy]-5-morpholin-4-ylpyridazin-3-yl]-4-methylphenyl]-2-(1,1-difluoropropyl)pyridine-4-carboxamide
CID 130425815
5-ethoxy-N-[3-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-4-methylphenyl]-2-(trifluoromethyl)pyridine-4-carboxamide;bis(N-[3-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-4-methylphenyl]-3-(methylsulfonimidoyl)benzamide);1-[3-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-4-methylphenyl]-2-(2-methylsulfonyl-4-pyridinyl)ethanone;2-[4-[2-[3-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-4-methylphenyl]-2-oxoethyl]-2-pyridinyl]-2-methylpropanenitrile;[[4-[2-[5-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-6-methyl-3-pyridinyl]-2-oxoethyl]-2-pyridinyl]-dimethyl-lambda4-sulfanyl]formonitrile
CID 157095397
2-cyclopropyl-N-[5-(6-methoxy-5-morpholin-4-ylpyridazin-3-yl)-6-methyl-3-pyridinyl]pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[5-(6-methoxy-5-morpholin-4-ylpyridazin-3-yl)-6-methyl-3-pyridinyl]pyridine-4-carboxamide;3-(difluoromethyl)-N-[5-(6-methoxy-5-morpholin-4-ylpyridazin-3-yl)-6-methyl-3-pyridinyl]benzamide;2-(1,1-difluoropropyl)-N-[5-(6-methoxy-5-morpholin-4-ylpyridazin-3-yl)-6-methyl-3-pyridinyl]pyridine-4-carboxamide;N-[5-(6-ethoxy-5-morpholin-4-ylpyridazin-3-yl)-6-methyl-3-pyridinyl]-3-(trifluoromethyl)benzamide;2-(2-fluoropropan-2-yl)-N-[5-(6-methoxy-5-morpholin-4-ylpyridazin-3-yl)-6-methyl-3-pyridinyl]pyridine-4-carboxamide;N-[5-(6-methoxy-5-morpholin-4-ylpyridazin-3-yl)-6-methyl-3-pyridinyl]-2-(trifluoromethyl)pyridine-4-carboxamide;N-[4-methyl-3-(6-methylsulfonyl-5-morpholin-4-ylpyridazin-3-yl)phenyl]-3-(trifluoromethyl)benzamide
CID 157258499
2-(1-cyanocyclopropyl)-N-[3-(6-ethoxy-5-morpholin-4-ylpyridazin-3-yl)-4-methylphenyl]pyridine-4-carboxamide;6-(2-cyanopropan-2-yl)-N-[3-(6-ethoxy-5-morpholin-4-ylpyridazin-3-yl)-4-methylphenyl]pyridazine-4-carboxamide;2-cyclopropyl-N-[3-(6-ethoxy-5-morpholin-4-ylpyridazin-3-yl)-4-methylphenyl]pyridine-4-carboxamide;2-(difluoromethyl)-N-[3-(6-ethoxy-5-morpholin-4-ylpyridazin-3-yl)-4-methylphenyl]pyridine-4-carboxamide;N-[5-(6-ethoxy-5-morpholin-4-ylpyridazin-3-yl)-2-fluoro-4-methylphenyl]-2-(2-fluoropropan-2-yl)pyridine-4-carboxamide;N-[3-(6-ethoxy-5-morpholin-4-ylpyridazin-3-yl)-4-methylphenyl]-2-(2-fluoropropan-2-yl)pyridine-4-carboxamide;N-[3-(6-ethoxy-5-morpholin-4-ylpyridazin-3-yl)-4-methylphenyl]-2-(trifluoromethyl)pyridine-4-carboxamide
CID 157274240
2-(2-cyanopropan-2-yl)-N-[4-methyl-3-[5-morpholin-4-yl-6-(oxan-4-yloxy)pyridazin-3-yl]phenyl]pyridine-4-carboxamide;N-ethyl-N-[6-methyl-5-[5-morpholin-4-yl-6-(oxan-4-yloxy)-3-pyridinyl]-3-pyridinyl]-3-(trifluoromethyl)benzamide;N-methyl-N-[6-methyl-5-[5-morpholin-4-yl-6-(oxan-4-yloxy)-3-pyridinyl]-3-pyridinyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-[5-morpholin-4-yl-6-(oxan-4-yloxy)pyridazin-3-yl]phenyl]-6-(trifluoromethyl)pyridazine-4-carboxamide;N-[6-methyl-5-[5-morpholin-4-yl-6-(oxan-4-yloxy)-3-pyridinyl]-3-pyridinyl]-2-propan-2-ylpyridine-4-carboxamide;N-[6-methyl-5-[5-morpholin-4-yl-6-(oxan-4-yloxy)-3-pyridinyl]-3-pyridinyl]-N-propyl-3-(trifluoromethyl)benzamide
CID 157325132

Frequently Asked Questions

What is the IUPAC name of 2-(2-cyanopropan-2-yl)-N-[3-[6-ethoxy-5-[(3R)-3-methylmorpholin-4-yl]pyridazin-3-yl]-4-methylphenyl]pyridine-4-carboxamide;2-(2-cyanopropan-2-yl)-N-[5-[6-ethoxy-5-[(3R)-3-methylmorpholin-4-yl]pyridazin-3-yl]-6-methyl-3-pyridinyl]pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[5-(6-ethoxy-5-morpholin-4-ylpyridazin-3-yl)-6-methyl-3-pyridinyl]pyridine-4-carboxamide;3-(difluoromethyl)-N-[5-(6-ethoxy-5-morpholin-4-ylpyridazin-3-yl)-6-methyl-3-pyridinyl]benzamide;N-[5-[6-ethoxy-5-[(3R)-3-methylmorpholin-4-yl]pyridazin-3-yl]-6-methyl-3-pyridinyl]-3-(trifluoromethyl)benzamide;N-[5-(6-ethoxy-5-morpholin-4-ylpyridazin-3-yl)-6-methyl-3-pyridinyl]-3-methylsulfonylbenzamide;N-[5-(6-ethoxy-5-morpholin-4-ylpyridazin-3-yl)-6-methyl-3-pyridinyl]-2-propan-2-ylpyridine-4-carboxamide;N-[5-[6-ethoxy-5-[2-(3H-pyrrol-2-yl)morpholin-4-yl]pyridazin-3-yl]-6-methyl-3-pyridinyl]-3-(trifluoromethyl)benzamide?
The IUPAC name of 2-(2-cyanopropan-2-yl)-N-[3-[6-ethoxy-5-[(3R)-3-methylmorpholin-4-yl]pyridazin-3-yl]-4-methylphenyl]pyridine-4-carboxamide;2-(2-cyanopropan-2-yl)-N-[5-[6-ethoxy-5-[(3R)-3-methylmorpholin-4-yl]pyridazin-3-yl]-6-methyl-3-pyridinyl]pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[5-(6-ethoxy-5-morpholin-4-ylpyridazin-3-yl)-6-methyl-3-pyridinyl]pyridine-4-carboxamide;3-(difluoromethyl)-N-[5-(6-ethoxy-5-morpholin-4-ylpyridazin-3-yl)-6-methyl-3-pyridinyl]benzamide;N-[5-[6-ethoxy-5-[(3R)-3-methylmorpholin-4-yl]pyridazin-3-yl]-6-methyl-3-pyridinyl]-3-(trifluoromethyl)benzamide;N-[5-(6-ethoxy-5-morpholin-4-ylpyridazin-3-yl)-6-methyl-3-pyridinyl]-3-methylsulfonylbenzamide;N-[5-(6-ethoxy-5-morpholin-4-ylpyridazin-3-yl)-6-methyl-3-pyridinyl]-2-propan-2-ylpyridine-4-carboxamide;N-[5-[6-ethoxy-5-[2-(3H-pyrrol-2-yl)morpholin-4-yl]pyridazin-3-yl]-6-methyl-3-pyridinyl]-3-(trifluoromethyl)benzamide (CID 157268806) is 2-(2-cyanopropan-2-yl)-N-[3-[6-ethoxy-5-[(3R)-3-methylmorpholin-4-yl]pyridazin-3-yl]-4-methylphenyl]pyridine-4-carboxamide;2-(2-cyanopropan-2-yl)-N-[5-[6-ethoxy-5-[(3R)-3-methylmorpholin-4-yl]pyridazin-3-yl]-6-methyl-3-pyridinyl]pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[5-(6-ethoxy-5-morpholin-4-ylpyridazin-3-yl)-6-methyl-3-pyridinyl]pyridine-4-carboxamide;3-(difluoromethyl)-N-[5-(6-ethoxy-5-morpholin-4-ylpyridazin-3-yl)-6-methyl-3-pyridinyl]benzamide;N-[5-[6-ethoxy-5-[(3R)-3-methylmorpholin-4-yl]pyridazin-3-yl]-6-methyl-3-pyridinyl]-3-(trifluoromethyl)benzamide;N-[5-(6-ethoxy-5-morpholin-4-ylpyridazin-3-yl)-6-methyl-3-pyridinyl]-3-methylsulfonylbenzamide;N-[5-(6-ethoxy-5-morpholin-4-ylpyridazin-3-yl)-6-methyl-3-pyridinyl]-2-propan-2-ylpyridine-4-carboxamide;N-[5-[6-ethoxy-5-[2-(3H-pyrrol-2-yl)morpholin-4-yl]pyridazin-3-yl]-6-methyl-3-pyridinyl]-3-(trifluoromethyl)benzamide.
What is the SMILES notation for 2-(2-cyanopropan-2-yl)-N-[3-[6-ethoxy-5-[(3R)-3-methylmorpholin-4-yl]pyridazin-3-yl]-4-methylphenyl]pyridine-4-carboxamide;2-(2-cyanopropan-2-yl)-N-[5-[6-ethoxy-5-[(3R)-3-methylmorpholin-4-yl]pyridazin-3-yl]-6-methyl-3-pyridinyl]pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[5-(6-ethoxy-5-morpholin-4-ylpyridazin-3-yl)-6-methyl-3-pyridinyl]pyridine-4-carboxamide;3-(difluoromethyl)-N-[5-(6-ethoxy-5-morpholin-4-ylpyridazin-3-yl)-6-methyl-3-pyridinyl]benzamide;N-[5-[6-ethoxy-5-[(3R)-3-methylmorpholin-4-yl]pyridazin-3-yl]-6-methyl-3-pyridinyl]-3-(trifluoromethyl)benzamide;N-[5-(6-ethoxy-5-morpholin-4-ylpyridazin-3-yl)-6-methyl-3-pyridinyl]-3-methylsulfonylbenzamide;N-[5-(6-ethoxy-5-morpholin-4-ylpyridazin-3-yl)-6-methyl-3-pyridinyl]-2-propan-2-ylpyridine-4-carboxamide;N-[5-[6-ethoxy-5-[2-(3H-pyrrol-2-yl)morpholin-4-yl]pyridazin-3-yl]-6-methyl-3-pyridinyl]-3-(trifluoromethyl)benzamide?
The canonical SMILES for 2-(2-cyanopropan-2-yl)-N-[3-[6-ethoxy-5-[(3R)-3-methylmorpholin-4-yl]pyridazin-3-yl]-4-methylphenyl]pyridine-4-carboxamide;2-(2-cyanopropan-2-yl)-N-[5-[6-ethoxy-5-[(3R)-3-methylmorpholin-4-yl]pyridazin-3-yl]-6-methyl-3-pyridinyl]pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[5-(6-ethoxy-5-morpholin-4-ylpyridazin-3-yl)-6-methyl-3-pyridinyl]pyridine-4-carboxamide;3-(difluoromethyl)-N-[5-(6-ethoxy-5-morpholin-4-ylpyridazin-3-yl)-6-methyl-3-pyridinyl]benzamide;N-[5-[6-ethoxy-5-[(3R)-3-methylmorpholin-4-yl]pyridazin-3-yl]-6-methyl-3-pyridinyl]-3-(trifluoromethyl)benzamide;N-[5-(6-ethoxy-5-morpholin-4-ylpyridazin-3-yl)-6-methyl-3-pyridinyl]-3-methylsulfonylbenzamide;N-[5-(6-ethoxy-5-morpholin-4-ylpyridazin-3-yl)-6-methyl-3-pyridinyl]-2-propan-2-ylpyridine-4-carboxamide;N-[5-[6-ethoxy-5-[2-(3H-pyrrol-2-yl)morpholin-4-yl]pyridazin-3-yl]-6-methyl-3-pyridinyl]-3-(trifluoromethyl)benzamide is CCOc1nnc(-c2cc(NC(=O)c3cccc(C(F)(F)F)c3)cnc2C)cc1N1CCOC(C2=NC=CC2)C1.CCOc1nnc(-c2cc(NC(=O)c3cccc(C(F)(F)F)c3)cnc2C)cc1N1CCOC[C@H]1C.CCOc1nnc(-c2cc(NC(=O)c3cccc(C(F)F)c3)cnc2C)cc1N1CCOCC1.CCOc1nnc(-c2cc(NC(=O)c3cccc(S(C)(=O)=O)c3)cnc2C)cc1N1CCOCC1.CCOc1nnc(-c2cc(NC(=O)c3ccnc(C(C)(C)C#N)c3)ccc2C)cc1N1CCOC[C@H]1C.CCOc1nnc(-c2cc(NC(=O)c3ccnc(C(C)(C)C#N)c3)cnc2C)cc1N1CCOC[C@H]1C.CCOc1nnc(-c2cc(NC(=O)c3ccnc(C(C)(F)F)c3)cnc2C)cc1N1CCOCC1.CCOc1nnc(-c2cc(NC(=O)c3ccnc(C(C)C)c3)cnc2C)cc1N1CCOCC1.
What is the InChIKey of 2-(2-cyanopropan-2-yl)-N-[3-[6-ethoxy-5-[(3R)-3-methylmorpholin-4-yl]pyridazin-3-yl]-4-methylphenyl]pyridine-4-carboxamide;2-(2-cyanopropan-2-yl)-N-[5-[6-ethoxy-5-[(3R)-3-methylmorpholin-4-yl]pyridazin-3-yl]-6-methyl-3-pyridinyl]pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[5-(6-ethoxy-5-morpholin-4-ylpyridazin-3-yl)-6-methyl-3-pyridinyl]pyridine-4-carboxamide;3-(difluoromethyl)-N-[5-(6-ethoxy-5-morpholin-4-ylpyridazin-3-yl)-6-methyl-3-pyridinyl]benzamide;N-[5-[6-ethoxy-5-[(3R)-3-methylmorpholin-4-yl]pyridazin-3-yl]-6-methyl-3-pyridinyl]-3-(trifluoromethyl)benzamide;N-[5-(6-ethoxy-5-morpholin-4-ylpyridazin-3-yl)-6-methyl-3-pyridinyl]-3-methylsulfonylbenzamide;N-[5-(6-ethoxy-5-morpholin-4-ylpyridazin-3-yl)-6-methyl-3-pyridinyl]-2-propan-2-ylpyridine-4-carboxamide;N-[5-[6-ethoxy-5-[2-(3H-pyrrol-2-yl)morpholin-4-yl]pyridazin-3-yl]-6-methyl-3-pyridinyl]-3-(trifluoromethyl)benzamide?
The InChIKey is AYHLLDDVBGQHQA-JEFPUCOLSA-N. The full InChI is InChI=1S/C28H27F3N6O3.C28H32N6O3.C27H31N7O3.C25H26F3N5O3.C25H30N6O3.C24H26F2N6O3.C24H25F2N5O3.C24H27N5O5S/c1-3-39-27-24(37-10-11-40-25(16-37)22-8-5-9-32-22)14-23(35-36-27)21-13-20(15-33-17(21)2)34-26(38)18-6-4-7-19(12-18)28(29,30)31;1-6-37-27-24(34-11-12-36-16-19(34)3)15-23(32-33-27)22-14-21(8-7-18(22)2)31-26(35)20-9-10-30-25(13-20)28(4,5)17-29;1-6-37-26-23(34-9-10-36-15-17(34)2)13-22(32-33-26)21-12-20(14-30-18(21)3)31-25(35)19-7-8-29-24(11-19)27(4,5)16-28;1-4-36-24-22(33-8-9-35-14-15(33)2)12-21(31-32-24)20-11-19(13-29-16(20)3)30-23(34)17-6-5-7-18(10-17)25(26,27)28;1-5-34-25-23(31-8-10-33-11-9-31)14-22(29-30-25)20-13-19(15-27-17(20)4)28-24(32)18-6-7-26-21(12-18)16(2)3;1-4-35-23-20(32-7-9-34-10-8-32)13-19(30-31-23)18-12-17(14-28-15(18)2)29-22(33)16-5-6-27-21(11-16)24(3,25)26;1-3-34-24-21(31-7-9-33-10-8-31)13-20(29-30-24)19-12-18(14-27-15(19)2)28-23(32)17-6-4-5-16(11-17)22(25)26;1-4-34-24-22(29-8-10-33-11-9-29)14-21(27-28-24)20-13-18(15-25-16(20)2)26-23(30)17-6-5-7-19(12-17)35(3,31)32/h4-7,9,12-15,25H,3,8,10-11,16H2,1-2H3,(H,34,38);7-10,13-15,19H,6,11-12,16H2,1-5H3,(H,31,35);7-8,11-14,17H,6,9-10,15H2,1-5H3,(H,31,35);5-7,10-13,15H,4,8-9,14H2,1-3H3,(H,30,34);6-7,12-16H,5,8-11H2,1-4H3,(H,28,32);5-6,11-14H,4,7-10H2,1-3H3,(H,29,33);4-6,11-14,22H,3,7-10H2,1-2H3,(H,28,32);5-7,12-15H,4,8-11H2,1-3H3,(H,26,30)/t;19-;17-;15-;;;;/m.111..../s1.
What are the key properties of 2-(2-cyanopropan-2-yl)-N-[3-[6-ethoxy-5-[(3R)-3-methylmorpholin-4-yl]pyridazin-3-yl]-4-methylphenyl]pyridine-4-carboxamide;2-(2-cyanopropan-2-yl)-N-[5-[6-ethoxy-5-[(3R)-3-methylmorpholin-4-yl]pyridazin-3-yl]-6-methyl-3-pyridinyl]pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[5-(6-ethoxy-5-morpholin-4-ylpyridazin-3-yl)-6-methyl-3-pyridinyl]pyridine-4-carboxamide;3-(difluoromethyl)-N-[5-(6-ethoxy-5-morpholin-4-ylpyridazin-3-yl)-6-methyl-3-pyridinyl]benzamide;N-[5-[6-ethoxy-5-[(3R)-3-methylmorpholin-4-yl]pyridazin-3-yl]-6-methyl-3-pyridinyl]-3-(trifluoromethyl)benzamide;N-[5-(6-ethoxy-5-morpholin-4-ylpyridazin-3-yl)-6-methyl-3-pyridinyl]-3-methylsulfonylbenzamide;N-[5-(6-ethoxy-5-morpholin-4-ylpyridazin-3-yl)-6-methyl-3-pyridinyl]-2-propan-2-ylpyridine-4-carboxamide;N-[5-[6-ethoxy-5-[2-(3H-pyrrol-2-yl)morpholin-4-yl]pyridazin-3-yl]-6-methyl-3-pyridinyl]-3-(trifluoromethyl)benzamide?
2-(2-cyanopropan-2-yl)-N-[3-[6-ethoxy-5-[(3R)-3-methylmorpholin-4-yl]pyridazin-3-yl]-4-methylphenyl]pyridine-4-carboxamide;2-(2-cyanopropan-2-yl)-N-[5-[6-ethoxy-5-[(3R)-3-methylmorpholin-4-yl]pyridazin-3-yl]-6-methyl-3-pyridinyl]pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[5-(6-ethoxy-5-morpholin-4-ylpyridazin-3-yl)-6-methyl-3-pyridinyl]pyridine-4-carboxamide;3-(difluoromethyl)-N-[5-(6-ethoxy-5-morpholin-4-ylpyridazin-3-yl)-6-methyl-3-pyridinyl]benzamide;N-[5-[6-ethoxy-5-[(3R)-3-methylmorpholin-4-yl]pyridazin-3-yl]-6-methyl-3-pyridinyl]-3-(trifluoromethyl)benzamide;N-[5-(6-ethoxy-5-morpholin-4-ylpyridazin-3-yl)-6-methyl-3-pyridinyl]-3-methylsulfonylbenzamide;N-[5-(6-ethoxy-5-morpholin-4-ylpyridazin-3-yl)-6-methyl-3-pyridinyl]-2-propan-2-ylpyridine-4-carboxamide;N-[5-[6-ethoxy-5-[2-(3H-pyrrol-2-yl)morpholin-4-yl]pyridazin-3-yl]-6-methyl-3-pyridinyl]-3-(trifluoromethyl)benzamide has a molecular weight of 3970.39 g/mol, XLogP of 32.97, 55 rotatable bonds, 8 hydrogen bond donors, and 64 hydrogen bond acceptors.
Where does this data come from?
All data for 2-(2-cyanopropan-2-yl)-N-[3-[6-ethoxy-5-[(3R)-3-methylmorpholin-4-yl]pyridazin-3-yl]-4-methylphenyl]pyridine-4-carboxamide;2-(2-cyanopropan-2-yl)-N-[5-[6-ethoxy-5-[(3R)-3-methylmorpholin-4-yl]pyridazin-3-yl]-6-methyl-3-pyridinyl]pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[5-(6-ethoxy-5-morpholin-4-ylpyridazin-3-yl)-6-methyl-3-pyridinyl]pyridine-4-carboxamide;3-(difluoromethyl)-N-[5-(6-ethoxy-5-morpholin-4-ylpyridazin-3-yl)-6-methyl-3-pyridinyl]benzamide;N-[5-[6-ethoxy-5-[(3R)-3-methylmorpholin-4-yl]pyridazin-3-yl]-6-methyl-3-pyridinyl]-3-(trifluoromethyl)benzamide;N-[5-(6-ethoxy-5-morpholin-4-ylpyridazin-3-yl)-6-methyl-3-pyridinyl]-3-methylsulfonylbenzamide;N-[5-(6-ethoxy-5-morpholin-4-ylpyridazin-3-yl)-6-methyl-3-pyridinyl]-2-propan-2-ylpyridine-4-carboxamide;N-[5-[6-ethoxy-5-[2-(3H-pyrrol-2-yl)morpholin-4-yl]pyridazin-3-yl]-6-methyl-3-pyridinyl]-3-(trifluoromethyl)benzamide is sourced from PubChem (CID 157268806), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).