5-chloro-N-[1-[1-(3,4-dimethoxyphenyl)pyrazol-4-yl]ethyl]-1H-indole-2-carboxamide;5-chloro-7-fluoro-N-[1-(1-methylpyrazol-4-yl)cyclopropyl]-1H-indole-2-carboxamide;5-chloro-6-fluoro-N-(1-phenylcyclopropyl)-1H-indole-2-carboxamide;5-chloro-6-fluoro-N-[(1R)-1-phenylethyl]-1H-indole-2-carboxamide;5-chloro-6-fluoro-N-(3-phenyloxetan-3-yl)-1H-indole-2-carboxamide;6-(difluoromethyl)-N-[1-(1-methylpyrazol-4-yl)cyclopropyl]-1H-indole-2-carboxamide;5-hydroxy-N-[1-(1-methylpyrazol-4-yl)cyclopropyl]-1H-indole-2-carboxamide

C124H109Cl5F6N22O11 — CID 157278174

About 5-chloro-N-[1-[1-(3,4-dimethoxyphenyl)pyrazol-4-yl]ethyl]-1H-indole-2-carboxamide;5-chloro-7-fluoro-N-[1-(1-methylpyrazol-4-yl)cyclopropyl]-1H-indole-2-carboxamide;5-chloro-6-fluoro-N-(1-phenylcyclopropyl)-1H-indole-2-carboxamide;5-chloro-6-fluoro-N-[(1R)-1-phenylethyl]-1H-indole-2-carboxamide;5-chloro-6-fluoro-N-(3-phenyloxetan-3-yl)-1H-indole-2-carboxamide;6-(difluoromethyl)-N-[1-(1-methylpyrazol-4-yl)cyclopropyl]-1H-indole-2-carboxamide;5-hydroxy-N-[1-(1-methylpyrazol-4-yl)cyclopropyl]-1H-indole-2-carboxamide

5-chloro-N-[1-[1-(3,4-dimethoxyphenyl)pyrazol-4-yl]ethyl]-1H-indole-2-carboxamide;5-chloro-7-fluoro-N-[1-(1-methylpyrazol-4-yl)cyclopropyl]-1H-indole-2-carboxamide;5-chloro-6-fluoro-N-(1-phenylcyclopropyl)-1H-indole-2-carboxamide;5-chloro-6-fluoro-N-[(1R)-1-phenylethyl]-1H-indole-2-carboxamide;5-chloro-6-fluoro-N-(3-phenyloxetan-3-yl)-1H-indole-2-carboxamide;6-(difluoromethyl)-N-[1-(1-methylpyrazol-4-yl)cyclopropyl]-1H-indole-2-carboxamide;5-hydroxy-N-[1-(1-methylpyrazol-4-yl)cyclopropyl]-1H-indole-2-carboxamide (PubChem CID 157278174) has the molecular formula C124H109Cl5F6N22O11 and a molecular weight of 2374.63 g/mol. Its IUPAC name is 5-chloro-N-[1-[1-(3,4-dimethoxyphenyl)pyrazol-4-yl]ethyl]-1H-indole-2-carboxamide;5-chloro-7-fluoro-N-[1-(1-methylpyrazol-4-yl)cyclopropyl]-1H-indole-2-carboxamide;5-chloro-6-fluoro-N-(1-phenylcyclopropyl)-1H-indole-2-carboxamide;5-chloro-6-fluoro-N-[(1R)-1-phenylethyl]-1H-indole-2-carboxamide;5-chloro-6-fluoro-N-(3-phenyloxetan-3-yl)-1H-indole-2-carboxamide;6-(difluoromethyl)-N-[1-(1-methylpyrazol-4-yl)cyclopropyl]-1H-indole-2-carboxamide;5-hydroxy-N-[1-(1-methylpyrazol-4-yl)cyclopropyl]-1H-indole-2-carboxamide.

Molecular Properties

• Compound Name: 5-chloro-N-[1-[1-(3,4-dimethoxyphenyl)pyrazol-4-yl]ethyl]-1H-indole-2-carboxamide;5-chloro-7-fluoro-N-[1-(1-methylpyrazol-4-yl)cyclopropyl]-1H-indole-2-carboxamide;5-chloro-6-fluoro-N-(1-phenylcyclopropyl)-1H-indole-2-carboxamide;5-chloro-6-fluoro-N-[(1R)-1-phenylethyl]-1H-indole-2-carboxamide;5-chloro-6-fluoro-N-(3-phenyloxetan-3-yl)-1H-indole-2-carboxamide;6-(difluoromethyl)-N-[1-(1-methylpyrazol-4-yl)cyclopropyl]-1H-indole-2-carboxamide;5-hydroxy-N-[1-(1-methylpyrazol-4-yl)cyclopropyl]-1H-indole-2-carboxamide
• PubChem CID: 157278174
• Molecular Formula: C124H109Cl5F6N22O11
• Molecular Weight: 2374.63 g/mol
• Exact Mass: 2370.70
• IUPAC Name: 5-chloro-N-[1-[1-(3,4-dimethoxyphenyl)pyrazol-4-yl]ethyl]-1H-indole-2-carboxamide;5-chloro-7-fluoro-N-[1-(1-methylpyrazol-4-yl)cyclopropyl]-1H-indole-2-carboxamide;5-chloro-6-fluoro-N-(1-phenylcyclopropyl)-1H-indole-2-carboxamide;5-chloro-6-fluoro-N-[(1R)-1-phenylethyl]-1H-indole-2-carboxamide;5-chloro-6-fluoro-N-(3-phenyloxetan-3-yl)-1H-indole-2-carboxamide;6-(difluoromethyl)-N-[1-(1-methylpyrazol-4-yl)cyclopropyl]-1H-indole-2-carboxamide;5-hydroxy-N-[1-(1-methylpyrazol-4-yl)cyclopropyl]-1H-indole-2-carboxamide
• SMILES: COc1ccc(-n2cc(C(C)NC(=O)c3cc4cc(Cl)ccc4[nH]3)cn2)cc1OC.C[C@@H](NC(=O)c1cc2cc(Cl)c(F)cc2[nH]1)c1ccccc1.Cn1cc(C2(NC(=O)c3cc4cc(Cl)cc(F)c4[nH]3)CC2)cn1.Cn1cc(C2(NC(=O)c3cc4cc(O)ccc4[nH]3)CC2)cn1.Cn1cc(C2(NC(=O)c3cc4ccc(C(F)F)cc4[nH]3)CC2)cn1.O=C(NC1(c2ccccc2)CC1)c1cc2cc(Cl)c(F)cc2[nH]1.O=C(NC1(c2ccccc2)COC1)c1cc2cc(Cl)c(F)cc2[nH]1
• InChI: InChI=1S/C22H21ClN4O3.C18H14ClFN2O2.C18H14ClFN2O.C17H14ClFN2O.C17H16F2N4O.C16H14ClFN4O.C16H16N4O2/c1-13(25-22(28)19-9-14-8-16(23)4-6-18(14)26-19)15-11-24-27(12-15)17-5-7-20(29-2)21(10-17)30-3;19-13-6-11-7-16(21-15(11)8-14(13)20)17(23)22-18(9-24-10-18)12-4-2-1-3-5-12;19-13-8-11-9-16(21-15(11)10-14(13)20)17(23)22-18(6-7-18)12-4-2-1-3-5-12;1-10(11-5-3-2-4-6-11)20-17(22)16-8-12-7-13(18)14(19)9-15(12)21-16;1-23-9-12(8-20-23)17(4-5-17)22-16(24)14-6-10-2-3-11(15(18)19)7-13(10)21-14;1-22-8-10(7-19-22)16(2-3-16)21-15(23)13-5-9-4-11(17)6-12(18)14(9)20-13;1-20-9-11(8-17-20)16(4-5-16)19-15(22)14-7-10-6-12(21)2-3-13(10)18-14/h4-13,26H,1-3H3,(H,25,28);1-8,21H,9-10H2,(H,22,23);1-5,8-10,21H,6-7H2,(H,22,23);2-10,21H,1H3,(H,20,22);2-3,6-9,15,21H,4-5H2,1H3,(H,22,24);4-8,20H,2-3H2,1H3,(H,21,23);2-3,6-9,18,21H,4-5H2,1H3,(H,19,22)/t;;;10-;;;/m...1.../s1
• InChIKey: AZIRBAHOIWHAIG-MKWAOLAESA-N
• XLogP: 25.36
• TPSA: 433.43 Ų
• H-Bond Donors: 15
• H-Bond Acceptors: 19
• Rotatable Bonds: 25
• Heavy Atoms: 168
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2374.63
LogP ≤ 5	25.36
H-Bond Donors ≤ 5	15
H-Bond Acceptors ≤ 10	19

Frequently Asked Questions

What is the IUPAC name of 5-chloro-N-[1-[1-(3,4-dimethoxyphenyl)pyrazol-4-yl]ethyl]-1H-indole-2-carboxamide;5-chloro-7-fluoro-N-[1-(1-methylpyrazol-4-yl)cyclopropyl]-1H-indole-2-carboxamide;5-chloro-6-fluoro-N-(1-phenylcyclopropyl)-1H-indole-2-carboxamide;5-chloro-6-fluoro-N-[(1R)-1-phenylethyl]-1H-indole-2-carboxamide;5-chloro-6-fluoro-N-(3-phenyloxetan-3-yl)-1H-indole-2-carboxamide;6-(difluoromethyl)-N-[1-(1-methylpyrazol-4-yl)cyclopropyl]-1H-indole-2-carboxamide;5-hydroxy-N-[1-(1-methylpyrazol-4-yl)cyclopropyl]-1H-indole-2-carboxamide?

The IUPAC name of 5-chloro-N-[1-[1-(3,4-dimethoxyphenyl)pyrazol-4-yl]ethyl]-1H-indole-2-carboxamide;5-chloro-7-fluoro-N-[1-(1-methylpyrazol-4-yl)cyclopropyl]-1H-indole-2-carboxamide;5-chloro-6-fluoro-N-(1-phenylcyclopropyl)-1H-indole-2-carboxamide;5-chloro-6-fluoro-N-[(1R)-1-phenylethyl]-1H-indole-2-carboxamide;5-chloro-6-fluoro-N-(3-phenyloxetan-3-yl)-1H-indole-2-carboxamide;6-(difluoromethyl)-N-[1-(1-methylpyrazol-4-yl)cyclopropyl]-1H-indole-2-carboxamide;5-hydroxy-N-[1-(1-methylpyrazol-4-yl)cyclopropyl]-1H-indole-2-carboxamide (CID 157278174) is 5-chloro-N-[1-[1-(3,4-dimethoxyphenyl)pyrazol-4-yl]ethyl]-1H-indole-2-carboxamide;5-chloro-7-fluoro-N-[1-(1-methylpyrazol-4-yl)cyclopropyl]-1H-indole-2-carboxamide;5-chloro-6-fluoro-N-(1-phenylcyclopropyl)-1H-indole-2-carboxamide;5-chloro-6-fluoro-N-[(1R)-1-phenylethyl]-1H-indole-2-carboxamide;5-chloro-6-fluoro-N-(3-phenyloxetan-3-yl)-1H-indole-2-carboxamide;6-(difluoromethyl)-N-[1-(1-methylpyrazol-4-yl)cyclopropyl]-1H-indole-2-carboxamide;5-hydroxy-N-[1-(1-methylpyrazol-4-yl)cyclopropyl]-1H-indole-2-carboxamide.

What is the SMILES notation for 5-chloro-N-[1-[1-(3,4-dimethoxyphenyl)pyrazol-4-yl]ethyl]-1H-indole-2-carboxamide;5-chloro-7-fluoro-N-[1-(1-methylpyrazol-4-yl)cyclopropyl]-1H-indole-2-carboxamide;5-chloro-6-fluoro-N-(1-phenylcyclopropyl)-1H-indole-2-carboxamide;5-chloro-6-fluoro-N-[(1R)-1-phenylethyl]-1H-indole-2-carboxamide;5-chloro-6-fluoro-N-(3-phenyloxetan-3-yl)-1H-indole-2-carboxamide;6-(difluoromethyl)-N-[1-(1-methylpyrazol-4-yl)cyclopropyl]-1H-indole-2-carboxamide;5-hydroxy-N-[1-(1-methylpyrazol-4-yl)cyclopropyl]-1H-indole-2-carboxamide?

The canonical SMILES for 5-chloro-N-[1-[1-(3,4-dimethoxyphenyl)pyrazol-4-yl]ethyl]-1H-indole-2-carboxamide;5-chloro-7-fluoro-N-[1-(1-methylpyrazol-4-yl)cyclopropyl]-1H-indole-2-carboxamide;5-chloro-6-fluoro-N-(1-phenylcyclopropyl)-1H-indole-2-carboxamide;5-chloro-6-fluoro-N-[(1R)-1-phenylethyl]-1H-indole-2-carboxamide;5-chloro-6-fluoro-N-(3-phenyloxetan-3-yl)-1H-indole-2-carboxamide;6-(difluoromethyl)-N-[1-(1-methylpyrazol-4-yl)cyclopropyl]-1H-indole-2-carboxamide;5-hydroxy-N-[1-(1-methylpyrazol-4-yl)cyclopropyl]-1H-indole-2-carboxamide is COc1ccc(-n2cc(C(C)NC(=O)c3cc4cc(Cl)ccc4[nH]3)cn2)cc1OC.C[C@@H](NC(=O)c1cc2cc(Cl)c(F)cc2[nH]1)c1ccccc1.Cn1cc(C2(NC(=O)c3cc4cc(Cl)cc(F)c4[nH]3)CC2)cn1.Cn1cc(C2(NC(=O)c3cc4cc(O)ccc4[nH]3)CC2)cn1.Cn1cc(C2(NC(=O)c3cc4ccc(C(F)F)cc4[nH]3)CC2)cn1.O=C(NC1(c2ccccc2)CC1)c1cc2cc(Cl)c(F)cc2[nH]1.O=C(NC1(c2ccccc2)COC1)c1cc2cc(Cl)c(F)cc2[nH]1.

What is the InChIKey of 5-chloro-N-[1-[1-(3,4-dimethoxyphenyl)pyrazol-4-yl]ethyl]-1H-indole-2-carboxamide;5-chloro-7-fluoro-N-[1-(1-methylpyrazol-4-yl)cyclopropyl]-1H-indole-2-carboxamide;5-chloro-6-fluoro-N-(1-phenylcyclopropyl)-1H-indole-2-carboxamide;5-chloro-6-fluoro-N-[(1R)-1-phenylethyl]-1H-indole-2-carboxamide;5-chloro-6-fluoro-N-(3-phenyloxetan-3-yl)-1H-indole-2-carboxamide;6-(difluoromethyl)-N-[1-(1-methylpyrazol-4-yl)cyclopropyl]-1H-indole-2-carboxamide;5-hydroxy-N-[1-(1-methylpyrazol-4-yl)cyclopropyl]-1H-indole-2-carboxamide?

The InChIKey is AZIRBAHOIWHAIG-MKWAOLAESA-N. The full InChI is InChI=1S/C22H21ClN4O3.C18H14ClFN2O2.C18H14ClFN2O.C17H14ClFN2O.C17H16F2N4O.C16H14ClFN4O.C16H16N4O2/c1-13(25-22(28)19-9-14-8-16(23)4-6-18(14)26-19)15-11-24-27(12-15)17-5-7-20(29-2)21(10-17)30-3;19-13-6-11-7-16(21-15(11)8-14(13)20)17(23)22-18(9-24-10-18)12-4-2-1-3-5-12;19-13-8-11-9-16(21-15(11)10-14(13)20)17(23)22-18(6-7-18)12-4-2-1-3-5-12;1-10(11-5-3-2-4-6-11)20-17(22)16-8-12-7-13(18)14(19)9-15(12)21-16;1-23-9-12(8-20-23)17(4-5-17)22-16(24)14-6-10-2-3-11(15(18)19)7-13(10)21-14;1-22-8-10(7-19-22)16(2-3-16)21-15(23)13-5-9-4-11(17)6-12(18)14(9)20-13;1-20-9-11(8-17-20)16(4-5-16)19-15(22)14-7-10-6-12(21)2-3-13(10)18-14/h4-13,26H,1-3H3,(H,25,28);1-8,21H,9-10H2,(H,22,23);1-5,8-10,21H,6-7H2,(H,22,23);2-10,21H,1H3,(H,20,22);2-3,6-9,15,21H,4-5H2,1H3,(H,22,24);4-8,20H,2-3H2,1H3,(H,21,23);2-3,6-9,18,21H,4-5H2,1H3,(H,19,22)/t;;;10-;;;/m...1.../s1.

What are the key properties of 5-chloro-N-[1-[1-(3,4-dimethoxyphenyl)pyrazol-4-yl]ethyl]-1H-indole-2-carboxamide;5-chloro-7-fluoro-N-[1-(1-methylpyrazol-4-yl)cyclopropyl]-1H-indole-2-carboxamide;5-chloro-6-fluoro-N-(1-phenylcyclopropyl)-1H-indole-2-carboxamide;5-chloro-6-fluoro-N-[(1R)-1-phenylethyl]-1H-indole-2-carboxamide;5-chloro-6-fluoro-N-(3-phenyloxetan-3-yl)-1H-indole-2-carboxamide;6-(difluoromethyl)-N-[1-(1-methylpyrazol-4-yl)cyclopropyl]-1H-indole-2-carboxamide;5-hydroxy-N-[1-(1-methylpyrazol-4-yl)cyclopropyl]-1H-indole-2-carboxamide?

5-chloro-N-[1-[1-(3,4-dimethoxyphenyl)pyrazol-4-yl]ethyl]-1H-indole-2-carboxamide;5-chloro-7-fluoro-N-[1-(1-methylpyrazol-4-yl)cyclopropyl]-1H-indole-2-carboxamide;5-chloro-6-fluoro-N-(1-phenylcyclopropyl)-1H-indole-2-carboxamide;5-chloro-6-fluoro-N-[(1R)-1-phenylethyl]-1H-indole-2-carboxamide;5-chloro-6-fluoro-N-(3-phenyloxetan-3-yl)-1H-indole-2-carboxamide;6-(difluoromethyl)-N-[1-(1-methylpyrazol-4-yl)cyclopropyl]-1H-indole-2-carboxamide;5-hydroxy-N-[1-(1-methylpyrazol-4-yl)cyclopropyl]-1H-indole-2-carboxamide has a molecular weight of 2374.63 g/mol, XLogP of 25.36, 25 rotatable bonds, 15 hydrogen bond donors, and 19 hydrogen bond acceptors.

Where does this data come from?

All data for 5-chloro-N-[1-[1-(3,4-dimethoxyphenyl)pyrazol-4-yl]ethyl]-1H-indole-2-carboxamide;5-chloro-7-fluoro-N-[1-(1-methylpyrazol-4-yl)cyclopropyl]-1H-indole-2-carboxamide;5-chloro-6-fluoro-N-(1-phenylcyclopropyl)-1H-indole-2-carboxamide;5-chloro-6-fluoro-N-[(1R)-1-phenylethyl]-1H-indole-2-carboxamide;5-chloro-6-fluoro-N-(3-phenyloxetan-3-yl)-1H-indole-2-carboxamide;6-(difluoromethyl)-N-[1-(1-methylpyrazol-4-yl)cyclopropyl]-1H-indole-2-carboxamide;5-hydroxy-N-[1-(1-methylpyrazol-4-yl)cyclopropyl]-1H-indole-2-carboxamide is sourced from PubChem (CID 157278174), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).