(3R)-3-[5-(6-amino-3-pyridinyl)furo[3,2-b]pyridin-2-yl]-3-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]pyrrolidine-2,5-dione;(3R)-3-[(4-fluoro-5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-3-furo[2,3-c]pyridin-2-ylpyrrolidine-2,5-dione;(3R)-3-(5-imidazol-1-ylfuro[3,2-b]pyridin-2-yl)-3-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]pyrrolidine-2,5-dione;5-[2-[(4S)-4-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-2,5-dioxoimidazolidin-4-yl]furo[2,3-b]pyridin-5-yl]-5-methylimidazolidine-2,4-dione;(3R)-3-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-3-[5-(pyridin-3-ylamino)furo[3,2-b]pyridin-2-yl]pyrrolidine-2,5-dione

C121H97FN24O27 — CID 157288556

About (3R)-3-[5-(6-amino-3-pyridinyl)furo[3,2-b]pyridin-2-yl]-3-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]pyrrolidine-2,5-dione;(3R)-3-[(4-fluoro-5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-3-furo[2,3-c]pyridin-2-ylpyrrolidine-2,5-dione;(3R)-3-(5-imidazol-1-ylfuro[3,2-b]pyridin-2-yl)-3-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]pyrrolidine-2,5-dione;5-[2-[(4S)-4-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-2,5-dioxoimidazolidin-4-yl]furo[2,3-b]pyridin-5-yl]-5-methylimidazolidine-2,4-dione;(3R)-3-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-3-[5-(pyridin-3-ylamino)furo[3,2-b]pyridin-2-yl]pyrrolidine-2,5-dione

(3R)-3-[5-(6-amino-3-pyridinyl)furo[3,2-b]pyridin-2-yl]-3-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]pyrrolidine-2,5-dione;(3R)-3-[(4-fluoro-5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-3-furo[2,3-c]pyridin-2-ylpyrrolidine-2,5-dione;(3R)-3-(5-imidazol-1-ylfuro[3,2-b]pyridin-2-yl)-3-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]pyrrolidine-2,5-dione;5-[2-[(4S)-4-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-2,5-dioxoimidazolidin-4-yl]furo[2,3-b]pyridin-5-yl]-5-methylimidazolidine-2,4-dione;(3R)-3-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-3-[5-(pyridin-3-ylamino)furo[3,2-b]pyridin-2-yl]pyrrolidine-2,5-dione (PubChem CID 157288556) has the molecular formula C121H97FN24O27 and a molecular weight of 2338.25 g/mol. Its IUPAC name is (3R)-3-[5-(6-amino-3-pyridinyl)furo[3,2-b]pyridin-2-yl]-3-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]pyrrolidine-2,5-dione;(3R)-3-[(4-fluoro-5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-3-furo[2,3-c]pyridin-2-ylpyrrolidine-2,5-dione;(3R)-3-(5-imidazol-1-ylfuro[3,2-b]pyridin-2-yl)-3-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]pyrrolidine-2,5-dione;5-[2-[(4S)-4-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-2,5-dioxoimidazolidin-4-yl]furo[2,3-b]pyridin-5-yl]-5-methylimidazolidine-2,4-dione;(3R)-3-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-3-[5-(pyridin-3-ylamino)furo[3,2-b]pyridin-2-yl]pyrrolidine-2,5-dione.

Molecular Properties

• Compound Name: (3R)-3-[5-(6-amino-3-pyridinyl)furo[3,2-b]pyridin-2-yl]-3-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]pyrrolidine-2,5-dione;(3R)-3-[(4-fluoro-5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-3-furo[2,3-c]pyridin-2-ylpyrrolidine-2,5-dione;(3R)-3-(5-imidazol-1-ylfuro[3,2-b]pyridin-2-yl)-3-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]pyrrolidine-2,5-dione;5-[2-[(4S)-4-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-2,5-dioxoimidazolidin-4-yl]furo[2,3-b]pyridin-5-yl]-5-methylimidazolidine-2,4-dione;(3R)-3-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-3-[5-(pyridin-3-ylamino)furo[3,2-b]pyridin-2-yl]pyrrolidine-2,5-dione
• PubChem CID: 157288556
• Molecular Formula: C121H97FN24O27
• Molecular Weight: 2338.25 g/mol
• Exact Mass: 2336.69
• IUPAC Name: (3R)-3-[5-(6-amino-3-pyridinyl)furo[3,2-b]pyridin-2-yl]-3-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]pyrrolidine-2,5-dione;(3R)-3-[(4-fluoro-5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-3-furo[2,3-c]pyridin-2-ylpyrrolidine-2,5-dione;(3R)-3-(5-imidazol-1-ylfuro[3,2-b]pyridin-2-yl)-3-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]pyrrolidine-2,5-dione;5-[2-[(4S)-4-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-2,5-dioxoimidazolidin-4-yl]furo[2,3-b]pyridin-5-yl]-5-methylimidazolidine-2,4-dione;(3R)-3-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-3-[5-(pyridin-3-ylamino)furo[3,2-b]pyridin-2-yl]pyrrolidine-2,5-dione
• SMILES: COc1ccc2c(c1)C(=O)N(C[C@@]1(c3cc4cc(C5(C)NC(=O)NC5=O)cnc4o3)NC(=O)NC1=O)C2.COc1ccc2c(c1)C(=O)N(C[C@@]1(c3cc4nc(-c5ccc(N)nc5)ccc4o3)CC(=O)NC1=O)C2.COc1ccc2c(c1)C(=O)N(C[C@@]1(c3cc4nc(-n5ccnc5)ccc4o3)CC(=O)NC1=O)C2.COc1ccc2c(c1)C(=O)N(C[C@@]1(c3cc4nc(Nc5cccnc5)ccc4o3)CC(=O)NC1=O)C2.COc1ccc2c(c1F)C(=O)N(C[C@@]1(c3cc4ccncc4o3)CC(=O)NC1=O)C2
• InChI: InChI=1S/2C26H21N5O5.C24H20N6O7.C24H19N5O5.C21H16FN3O5/c1-35-16-4-2-15-12-31(24(33)17(15)8-16)13-26(10-23(32)30-25(26)34)21-9-19-20(36-21)6-5-18(29-19)14-3-7-22(27)28-11-14;1-35-17-5-4-15-13-31(24(33)18(15)9-17)14-26(11-23(32)30-25(26)34)21-10-19-20(36-21)6-7-22(29-19)28-16-3-2-8-27-12-16;1-23(19(32)26-21(34)28-23)13-5-12-6-16(37-17(12)25-8-13)24(20(33)27-22(35)29-24)10-30-9-11-3-4-14(36-2)7-15(11)18(30)31;1-33-15-3-2-14-11-29(22(31)16(14)8-15)12-24(10-21(30)27-23(24)32)19-9-17-18(34-19)4-5-20(26-17)28-7-6-25-13-28;1-29-13-3-2-12-9-25(19(27)17(12)18(13)22)10-21(7-16(26)24-20(21)28)15-6-11-4-5-23-8-14(11)30-15/h2-9,11H,10,12-13H2,1H3,(H2,27,28)(H,30,32,34);2-10,12H,11,13-14H2,1H3,(H,28,29)(H,30,32,34);3-8H,9-10H2,1-2H3,(H2,26,28,32,34)(H2,27,29,33,35);2-9,13H,10-12H2,1H3,(H,27,30,32);2-6,8H,7,9-10H2,1H3,(H,24,26,28)/t2*26-;23?,24-;24-;21-/m11011/s1
• InChIKey: BANGZDIHDWYABU-TXBYRBIASA-N
• XLogP: 9.80
• TPSA: 660.58 Ų
• H-Bond Donors: 10
• H-Bond Acceptors: 38
• Rotatable Bonds: 25
• Heavy Atoms: 173
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2338.25
LogP ≤ 5	9.80
H-Bond Donors ≤ 5	10
H-Bond Acceptors ≤ 10	38

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': 'hydantoin', 'substructure': 'N/A'}, {'alert_name': 'phthalimide', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of (3R)-3-[5-(6-amino-3-pyridinyl)furo[3,2-b]pyridin-2-yl]-3-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]pyrrolidine-2,5-dione;(3R)-3-[(4-fluoro-5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-3-furo[2,3-c]pyridin-2-ylpyrrolidine-2,5-dione;(3R)-3-(5-imidazol-1-ylfuro[3,2-b]pyridin-2-yl)-3-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]pyrrolidine-2,5-dione;5-[2-[(4S)-4-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-2,5-dioxoimidazolidin-4-yl]furo[2,3-b]pyridin-5-yl]-5-methylimidazolidine-2,4-dione;(3R)-3-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-3-[5-(pyridin-3-ylamino)furo[3,2-b]pyridin-2-yl]pyrrolidine-2,5-dione?

The IUPAC name of (3R)-3-[5-(6-amino-3-pyridinyl)furo[3,2-b]pyridin-2-yl]-3-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]pyrrolidine-2,5-dione;(3R)-3-[(4-fluoro-5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-3-furo[2,3-c]pyridin-2-ylpyrrolidine-2,5-dione;(3R)-3-(5-imidazol-1-ylfuro[3,2-b]pyridin-2-yl)-3-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]pyrrolidine-2,5-dione;5-[2-[(4S)-4-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-2,5-dioxoimidazolidin-4-yl]furo[2,3-b]pyridin-5-yl]-5-methylimidazolidine-2,4-dione;(3R)-3-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-3-[5-(pyridin-3-ylamino)furo[3,2-b]pyridin-2-yl]pyrrolidine-2,5-dione (CID 157288556) is (3R)-3-[5-(6-amino-3-pyridinyl)furo[3,2-b]pyridin-2-yl]-3-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]pyrrolidine-2,5-dione;(3R)-3-[(4-fluoro-5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-3-furo[2,3-c]pyridin-2-ylpyrrolidine-2,5-dione;(3R)-3-(5-imidazol-1-ylfuro[3,2-b]pyridin-2-yl)-3-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]pyrrolidine-2,5-dione;5-[2-[(4S)-4-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-2,5-dioxoimidazolidin-4-yl]furo[2,3-b]pyridin-5-yl]-5-methylimidazolidine-2,4-dione;(3R)-3-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-3-[5-(pyridin-3-ylamino)furo[3,2-b]pyridin-2-yl]pyrrolidine-2,5-dione.

What is the SMILES notation for (3R)-3-[5-(6-amino-3-pyridinyl)furo[3,2-b]pyridin-2-yl]-3-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]pyrrolidine-2,5-dione;(3R)-3-[(4-fluoro-5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-3-furo[2,3-c]pyridin-2-ylpyrrolidine-2,5-dione;(3R)-3-(5-imidazol-1-ylfuro[3,2-b]pyridin-2-yl)-3-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]pyrrolidine-2,5-dione;5-[2-[(4S)-4-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-2,5-dioxoimidazolidin-4-yl]furo[2,3-b]pyridin-5-yl]-5-methylimidazolidine-2,4-dione;(3R)-3-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-3-[5-(pyridin-3-ylamino)furo[3,2-b]pyridin-2-yl]pyrrolidine-2,5-dione?

The canonical SMILES for (3R)-3-[5-(6-amino-3-pyridinyl)furo[3,2-b]pyridin-2-yl]-3-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]pyrrolidine-2,5-dione;(3R)-3-[(4-fluoro-5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-3-furo[2,3-c]pyridin-2-ylpyrrolidine-2,5-dione;(3R)-3-(5-imidazol-1-ylfuro[3,2-b]pyridin-2-yl)-3-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]pyrrolidine-2,5-dione;5-[2-[(4S)-4-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-2,5-dioxoimidazolidin-4-yl]furo[2,3-b]pyridin-5-yl]-5-methylimidazolidine-2,4-dione;(3R)-3-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-3-[5-(pyridin-3-ylamino)furo[3,2-b]pyridin-2-yl]pyrrolidine-2,5-dione is COc1ccc2c(c1)C(=O)N(C[C@@]1(c3cc4cc(C5(C)NC(=O)NC5=O)cnc4o3)NC(=O)NC1=O)C2.COc1ccc2c(c1)C(=O)N(C[C@@]1(c3cc4nc(-c5ccc(N)nc5)ccc4o3)CC(=O)NC1=O)C2.COc1ccc2c(c1)C(=O)N(C[C@@]1(c3cc4nc(-n5ccnc5)ccc4o3)CC(=O)NC1=O)C2.COc1ccc2c(c1)C(=O)N(C[C@@]1(c3cc4nc(Nc5cccnc5)ccc4o3)CC(=O)NC1=O)C2.COc1ccc2c(c1F)C(=O)N(C[C@@]1(c3cc4ccncc4o3)CC(=O)NC1=O)C2.

What is the InChIKey of (3R)-3-[5-(6-amino-3-pyridinyl)furo[3,2-b]pyridin-2-yl]-3-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]pyrrolidine-2,5-dione;(3R)-3-[(4-fluoro-5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-3-furo[2,3-c]pyridin-2-ylpyrrolidine-2,5-dione;(3R)-3-(5-imidazol-1-ylfuro[3,2-b]pyridin-2-yl)-3-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]pyrrolidine-2,5-dione;5-[2-[(4S)-4-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-2,5-dioxoimidazolidin-4-yl]furo[2,3-b]pyridin-5-yl]-5-methylimidazolidine-2,4-dione;(3R)-3-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-3-[5-(pyridin-3-ylamino)furo[3,2-b]pyridin-2-yl]pyrrolidine-2,5-dione?

The InChIKey is BANGZDIHDWYABU-TXBYRBIASA-N. The full InChI is InChI=1S/2C26H21N5O5.C24H20N6O7.C24H19N5O5.C21H16FN3O5/c1-35-16-4-2-15-12-31(24(33)17(15)8-16)13-26(10-23(32)30-25(26)34)21-9-19-20(36-21)6-5-18(29-19)14-3-7-22(27)28-11-14;1-35-17-5-4-15-13-31(24(33)18(15)9-17)14-26(11-23(32)30-25(26)34)21-10-19-20(36-21)6-7-22(29-19)28-16-3-2-8-27-12-16;1-23(19(32)26-21(34)28-23)13-5-12-6-16(37-17(12)25-8-13)24(20(33)27-22(35)29-24)10-30-9-11-3-4-14(36-2)7-15(11)18(30)31;1-33-15-3-2-14-11-29(22(31)16(14)8-15)12-24(10-21(30)27-23(24)32)19-9-17-18(34-19)4-5-20(26-17)28-7-6-25-13-28;1-29-13-3-2-12-9-25(19(27)17(12)18(13)22)10-21(7-16(26)24-20(21)28)15-6-11-4-5-23-8-14(11)30-15/h2-9,11H,10,12-13H2,1H3,(H2,27,28)(H,30,32,34);2-10,12H,11,13-14H2,1H3,(H,28,29)(H,30,32,34);3-8H,9-10H2,1-2H3,(H2,26,28,32,34)(H2,27,29,33,35);2-9,13H,10-12H2,1H3,(H,27,30,32);2-6,8H,7,9-10H2,1H3,(H,24,26,28)/t2*26-;23?,24-;24-;21-/m11011/s1.

What are the key properties of (3R)-3-[5-(6-amino-3-pyridinyl)furo[3,2-b]pyridin-2-yl]-3-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]pyrrolidine-2,5-dione;(3R)-3-[(4-fluoro-5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-3-furo[2,3-c]pyridin-2-ylpyrrolidine-2,5-dione;(3R)-3-(5-imidazol-1-ylfuro[3,2-b]pyridin-2-yl)-3-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]pyrrolidine-2,5-dione;5-[2-[(4S)-4-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-2,5-dioxoimidazolidin-4-yl]furo[2,3-b]pyridin-5-yl]-5-methylimidazolidine-2,4-dione;(3R)-3-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-3-[5-(pyridin-3-ylamino)furo[3,2-b]pyridin-2-yl]pyrrolidine-2,5-dione?

(3R)-3-[5-(6-amino-3-pyridinyl)furo[3,2-b]pyridin-2-yl]-3-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]pyrrolidine-2,5-dione;(3R)-3-[(4-fluoro-5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-3-furo[2,3-c]pyridin-2-ylpyrrolidine-2,5-dione;(3R)-3-(5-imidazol-1-ylfuro[3,2-b]pyridin-2-yl)-3-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]pyrrolidine-2,5-dione;5-[2-[(4S)-4-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-2,5-dioxoimidazolidin-4-yl]furo[2,3-b]pyridin-5-yl]-5-methylimidazolidine-2,4-dione;(3R)-3-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-3-[5-(pyridin-3-ylamino)furo[3,2-b]pyridin-2-yl]pyrrolidine-2,5-dione has a molecular weight of 2338.25 g/mol, XLogP of 9.80, 25 rotatable bonds, 10 hydrogen bond donors, and 38 hydrogen bond acceptors.

Where does this data come from?

All data for (3R)-3-[5-(6-amino-3-pyridinyl)furo[3,2-b]pyridin-2-yl]-3-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]pyrrolidine-2,5-dione;(3R)-3-[(4-fluoro-5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-3-furo[2,3-c]pyridin-2-ylpyrrolidine-2,5-dione;(3R)-3-(5-imidazol-1-ylfuro[3,2-b]pyridin-2-yl)-3-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]pyrrolidine-2,5-dione;5-[2-[(4S)-4-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-2,5-dioxoimidazolidin-4-yl]furo[2,3-b]pyridin-5-yl]-5-methylimidazolidine-2,4-dione;(3R)-3-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-3-[5-(pyridin-3-ylamino)furo[3,2-b]pyridin-2-yl]pyrrolidine-2,5-dione is sourced from PubChem (CID 157288556), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).