N-(2-ethyl-5,6-dihydro-4H-cyclopenta[c]pyrazol-3-yl)-4-[6-methoxy-5-(4-methylimidazol-1-yl)-2-pyridinyl]-1,3-thiazol-2-amine;N-(2-ethyl-6,6-dimethyl-4,5-dihydrocyclopenta[c]pyrazol-3-yl)-4-[6-methoxy-5-(4-methylimidazol-1-yl)-2-pyridinyl]-1,3-thiazol-2-amine;N-(2-ethyl-4,5,6,7-tetrahydroindazol-3-yl)-4-[6-methoxy-5-(4-methylimidazol-1-yl)-2-pyridinyl]-5-methyl-1,3-thiazol-2-amine;2-(3,4,7,8,9,10-hexahydro-2H-pyrimido[1,2-b]indazol-1-yl)-4-[6-methoxy-5-(4-methylimidazol-1-yl)-2-pyridinyl]-1,3-thiazole;4-[6-methoxy-5-(4-methylimidazol-1-yl)-2-pyridinyl]-N-[1-methyl-3-[1-(trifluoromethyl)cyclopropyl]pyrazol-5-yl]-1,3-thiazol-2-amine

C111H122F3N35O5S5 — CID 157295405

About N-(2-ethyl-5,6-dihydro-4H-cyclopenta[c]pyrazol-3-yl)-4-[6-methoxy-5-(4-methylimidazol-1-yl)-2-pyridinyl]-1,3-thiazol-2-amine;N-(2-ethyl-6,6-dimethyl-4,5-dihydrocyclopenta[c]pyrazol-3-yl)-4-[6-methoxy-5-(4-methylimidazol-1-yl)-2-pyridinyl]-1,3-thiazol-2-amine;N-(2-ethyl-4,5,6,7-tetrahydroindazol-3-yl)-4-[6-methoxy-5-(4-methylimidazol-1-yl)-2-pyridinyl]-5-methyl-1,3-thiazol-2-amine;2-(3,4,7,8,9,10-hexahydro-2H-pyrimido[1,2-b]indazol-1-yl)-4-[6-methoxy-5-(4-methylimidazol-1-yl)-2-pyridinyl]-1,3-thiazole;4-[6-methoxy-5-(4-methylimidazol-1-yl)-2-pyridinyl]-N-[1-methyl-3-[1-(trifluoromethyl)cyclopropyl]pyrazol-5-yl]-1,3-thiazol-2-amine

N-(2-ethyl-5,6-dihydro-4H-cyclopenta[c]pyrazol-3-yl)-4-[6-methoxy-5-(4-methylimidazol-1-yl)-2-pyridinyl]-1,3-thiazol-2-amine;N-(2-ethyl-6,6-dimethyl-4,5-dihydrocyclopenta[c]pyrazol-3-yl)-4-[6-methoxy-5-(4-methylimidazol-1-yl)-2-pyridinyl]-1,3-thiazol-2-amine;N-(2-ethyl-4,5,6,7-tetrahydroindazol-3-yl)-4-[6-methoxy-5-(4-methylimidazol-1-yl)-2-pyridinyl]-5-methyl-1,3-thiazol-2-amine;2-(3,4,7,8,9,10-hexahydro-2H-pyrimido[1,2-b]indazol-1-yl)-4-[6-methoxy-5-(4-methylimidazol-1-yl)-2-pyridinyl]-1,3-thiazole;4-[6-methoxy-5-(4-methylimidazol-1-yl)-2-pyridinyl]-N-[1-methyl-3-[1-(trifluoromethyl)cyclopropyl]pyrazol-5-yl]-1,3-thiazol-2-amine (PubChem CID 157295405) has the molecular formula C111H122F3N35O5S5 and a molecular weight of 2243.77 g/mol. Its IUPAC name is N-(2-ethyl-5,6-dihydro-4H-cyclopenta[c]pyrazol-3-yl)-4-[6-methoxy-5-(4-methylimidazol-1-yl)-2-pyridinyl]-1,3-thiazol-2-amine;N-(2-ethyl-6,6-dimethyl-4,5-dihydrocyclopenta[c]pyrazol-3-yl)-4-[6-methoxy-5-(4-methylimidazol-1-yl)-2-pyridinyl]-1,3-thiazol-2-amine;N-(2-ethyl-4,5,6,7-tetrahydroindazol-3-yl)-4-[6-methoxy-5-(4-methylimidazol-1-yl)-2-pyridinyl]-5-methyl-1,3-thiazol-2-amine;2-(3,4,7,8,9,10-hexahydro-2H-pyrimido[1,2-b]indazol-1-yl)-4-[6-methoxy-5-(4-methylimidazol-1-yl)-2-pyridinyl]-1,3-thiazole;4-[6-methoxy-5-(4-methylimidazol-1-yl)-2-pyridinyl]-N-[1-methyl-3-[1-(trifluoromethyl)cyclopropyl]pyrazol-5-yl]-1,3-thiazol-2-amine.

Molecular Properties

• Compound Name: N-(2-ethyl-5,6-dihydro-4H-cyclopenta[c]pyrazol-3-yl)-4-[6-methoxy-5-(4-methylimidazol-1-yl)-2-pyridinyl]-1,3-thiazol-2-amine;N-(2-ethyl-6,6-dimethyl-4,5-dihydrocyclopenta[c]pyrazol-3-yl)-4-[6-methoxy-5-(4-methylimidazol-1-yl)-2-pyridinyl]-1,3-thiazol-2-amine;N-(2-ethyl-4,5,6,7-tetrahydroindazol-3-yl)-4-[6-methoxy-5-(4-methylimidazol-1-yl)-2-pyridinyl]-5-methyl-1,3-thiazol-2-amine;2-(3,4,7,8,9,10-hexahydro-2H-pyrimido[1,2-b]indazol-1-yl)-4-[6-methoxy-5-(4-methylimidazol-1-yl)-2-pyridinyl]-1,3-thiazole;4-[6-methoxy-5-(4-methylimidazol-1-yl)-2-pyridinyl]-N-[1-methyl-3-[1-(trifluoromethyl)cyclopropyl]pyrazol-5-yl]-1,3-thiazol-2-amine
• PubChem CID: 157295405
• Molecular Formula: C111H122F3N35O5S5
• Molecular Weight: 2243.77 g/mol
• Exact Mass: 2241.89
• IUPAC Name: N-(2-ethyl-5,6-dihydro-4H-cyclopenta[c]pyrazol-3-yl)-4-[6-methoxy-5-(4-methylimidazol-1-yl)-2-pyridinyl]-1,3-thiazol-2-amine;N-(2-ethyl-6,6-dimethyl-4,5-dihydrocyclopenta[c]pyrazol-3-yl)-4-[6-methoxy-5-(4-methylimidazol-1-yl)-2-pyridinyl]-1,3-thiazol-2-amine;N-(2-ethyl-4,5,6,7-tetrahydroindazol-3-yl)-4-[6-methoxy-5-(4-methylimidazol-1-yl)-2-pyridinyl]-5-methyl-1,3-thiazol-2-amine;2-(3,4,7,8,9,10-hexahydro-2H-pyrimido[1,2-b]indazol-1-yl)-4-[6-methoxy-5-(4-methylimidazol-1-yl)-2-pyridinyl]-1,3-thiazole;4-[6-methoxy-5-(4-methylimidazol-1-yl)-2-pyridinyl]-N-[1-methyl-3-[1-(trifluoromethyl)cyclopropyl]pyrazol-5-yl]-1,3-thiazol-2-amine
• SMILES: CCn1nc2c(c1Nc1nc(-c3ccc(-n4cnc(C)c4)c(OC)n3)c(C)s1)CCCC2.CCn1nc2c(c1Nc1nc(-c3ccc(-n4cnc(C)c4)c(OC)n3)cs1)CCC2.CCn1nc2c(c1Nc1nc(-c3ccc(-n4cnc(C)c4)c(OC)n3)cs1)CCC2(C)C.COc1nc(-c2csc(N3CCCn4nc5c(c43)CCCC5)n2)ccc1-n1cnc(C)c1.COc1nc(-c2csc(Nc3cc(C4(C(F)(F)F)CC4)nn3C)n2)ccc1-n1cnc(C)c1
• InChI: InChI=1S/C23H25N7OS.2C23H27N7OS.C21H20F3N7OS.C21H23N7OS/c1-15-12-28(14-24-15)20-9-8-18(25-21(20)31-2)19-13-32-23(26-19)29-10-5-11-30-22(29)16-6-3-4-7-17(16)27-30;1-6-30-20(15-9-10-23(3,4)19(15)28-30)27-22-26-17(12-32-22)16-7-8-18(21(25-16)31-5)29-11-14(2)24-13-29;1-5-30-21(16-8-6-7-9-17(16)28-30)27-23-26-20(15(3)32-23)18-10-11-19(22(25-18)31-4)29-12-14(2)24-13-29;1-12-9-31(11-25-12)15-5-4-13(26-18(15)32-3)14-10-33-19(27-14)28-17-8-16(29-30(17)2)20(6-7-20)21(22,23)24;1-4-28-19(14-6-5-7-15(14)26-28)25-21-24-17(11-30-21)16-8-9-18(20(23-16)29-3)27-10-13(2)22-12-27/h8-9,12-14H,3-7,10-11H2,1-2H3;7-8,11-13H,6,9-10H2,1-5H3,(H,26,27);10-13H,5-9H2,1-4H3,(H,26,27);4-5,8-11H,6-7H2,1-3H3,(H,27,28);8-12H,4-7H2,1-3H3,(H,24,25)
• InChIKey: BBHDIZIFHZSEAF-UHFFFAOYSA-N
• XLogP: 23.01
• TPSA: 404.61 Ų
• H-Bond Donors: 4
• H-Bond Acceptors: 45
• Rotatable Bonds: 28
• Heavy Atoms: 159
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	2243.77
LogP ≤ 5	23.01
H-Bond Donors ≤ 5	4
H-Bond Acceptors ≤ 10	45

Frequently Asked Questions

What is the IUPAC name of N-(2-ethyl-5,6-dihydro-4H-cyclopenta[c]pyrazol-3-yl)-4-[6-methoxy-5-(4-methylimidazol-1-yl)-2-pyridinyl]-1,3-thiazol-2-amine;N-(2-ethyl-6,6-dimethyl-4,5-dihydrocyclopenta[c]pyrazol-3-yl)-4-[6-methoxy-5-(4-methylimidazol-1-yl)-2-pyridinyl]-1,3-thiazol-2-amine;N-(2-ethyl-4,5,6,7-tetrahydroindazol-3-yl)-4-[6-methoxy-5-(4-methylimidazol-1-yl)-2-pyridinyl]-5-methyl-1,3-thiazol-2-amine;2-(3,4,7,8,9,10-hexahydro-2H-pyrimido[1,2-b]indazol-1-yl)-4-[6-methoxy-5-(4-methylimidazol-1-yl)-2-pyridinyl]-1,3-thiazole;4-[6-methoxy-5-(4-methylimidazol-1-yl)-2-pyridinyl]-N-[1-methyl-3-[1-(trifluoromethyl)cyclopropyl]pyrazol-5-yl]-1,3-thiazol-2-amine?

The IUPAC name of N-(2-ethyl-5,6-dihydro-4H-cyclopenta[c]pyrazol-3-yl)-4-[6-methoxy-5-(4-methylimidazol-1-yl)-2-pyridinyl]-1,3-thiazol-2-amine;N-(2-ethyl-6,6-dimethyl-4,5-dihydrocyclopenta[c]pyrazol-3-yl)-4-[6-methoxy-5-(4-methylimidazol-1-yl)-2-pyridinyl]-1,3-thiazol-2-amine;N-(2-ethyl-4,5,6,7-tetrahydroindazol-3-yl)-4-[6-methoxy-5-(4-methylimidazol-1-yl)-2-pyridinyl]-5-methyl-1,3-thiazol-2-amine;2-(3,4,7,8,9,10-hexahydro-2H-pyrimido[1,2-b]indazol-1-yl)-4-[6-methoxy-5-(4-methylimidazol-1-yl)-2-pyridinyl]-1,3-thiazole;4-[6-methoxy-5-(4-methylimidazol-1-yl)-2-pyridinyl]-N-[1-methyl-3-[1-(trifluoromethyl)cyclopropyl]pyrazol-5-yl]-1,3-thiazol-2-amine (CID 157295405) is N-(2-ethyl-5,6-dihydro-4H-cyclopenta[c]pyrazol-3-yl)-4-[6-methoxy-5-(4-methylimidazol-1-yl)-2-pyridinyl]-1,3-thiazol-2-amine;N-(2-ethyl-6,6-dimethyl-4,5-dihydrocyclopenta[c]pyrazol-3-yl)-4-[6-methoxy-5-(4-methylimidazol-1-yl)-2-pyridinyl]-1,3-thiazol-2-amine;N-(2-ethyl-4,5,6,7-tetrahydroindazol-3-yl)-4-[6-methoxy-5-(4-methylimidazol-1-yl)-2-pyridinyl]-5-methyl-1,3-thiazol-2-amine;2-(3,4,7,8,9,10-hexahydro-2H-pyrimido[1,2-b]indazol-1-yl)-4-[6-methoxy-5-(4-methylimidazol-1-yl)-2-pyridinyl]-1,3-thiazole;4-[6-methoxy-5-(4-methylimidazol-1-yl)-2-pyridinyl]-N-[1-methyl-3-[1-(trifluoromethyl)cyclopropyl]pyrazol-5-yl]-1,3-thiazol-2-amine.

What is the SMILES notation for N-(2-ethyl-5,6-dihydro-4H-cyclopenta[c]pyrazol-3-yl)-4-[6-methoxy-5-(4-methylimidazol-1-yl)-2-pyridinyl]-1,3-thiazol-2-amine;N-(2-ethyl-6,6-dimethyl-4,5-dihydrocyclopenta[c]pyrazol-3-yl)-4-[6-methoxy-5-(4-methylimidazol-1-yl)-2-pyridinyl]-1,3-thiazol-2-amine;N-(2-ethyl-4,5,6,7-tetrahydroindazol-3-yl)-4-[6-methoxy-5-(4-methylimidazol-1-yl)-2-pyridinyl]-5-methyl-1,3-thiazol-2-amine;2-(3,4,7,8,9,10-hexahydro-2H-pyrimido[1,2-b]indazol-1-yl)-4-[6-methoxy-5-(4-methylimidazol-1-yl)-2-pyridinyl]-1,3-thiazole;4-[6-methoxy-5-(4-methylimidazol-1-yl)-2-pyridinyl]-N-[1-methyl-3-[1-(trifluoromethyl)cyclopropyl]pyrazol-5-yl]-1,3-thiazol-2-amine?

The canonical SMILES for N-(2-ethyl-5,6-dihydro-4H-cyclopenta[c]pyrazol-3-yl)-4-[6-methoxy-5-(4-methylimidazol-1-yl)-2-pyridinyl]-1,3-thiazol-2-amine;N-(2-ethyl-6,6-dimethyl-4,5-dihydrocyclopenta[c]pyrazol-3-yl)-4-[6-methoxy-5-(4-methylimidazol-1-yl)-2-pyridinyl]-1,3-thiazol-2-amine;N-(2-ethyl-4,5,6,7-tetrahydroindazol-3-yl)-4-[6-methoxy-5-(4-methylimidazol-1-yl)-2-pyridinyl]-5-methyl-1,3-thiazol-2-amine;2-(3,4,7,8,9,10-hexahydro-2H-pyrimido[1,2-b]indazol-1-yl)-4-[6-methoxy-5-(4-methylimidazol-1-yl)-2-pyridinyl]-1,3-thiazole;4-[6-methoxy-5-(4-methylimidazol-1-yl)-2-pyridinyl]-N-[1-methyl-3-[1-(trifluoromethyl)cyclopropyl]pyrazol-5-yl]-1,3-thiazol-2-amine is CCn1nc2c(c1Nc1nc(-c3ccc(-n4cnc(C)c4)c(OC)n3)c(C)s1)CCCC2.CCn1nc2c(c1Nc1nc(-c3ccc(-n4cnc(C)c4)c(OC)n3)cs1)CCC2.CCn1nc2c(c1Nc1nc(-c3ccc(-n4cnc(C)c4)c(OC)n3)cs1)CCC2(C)C.COc1nc(-c2csc(N3CCCn4nc5c(c43)CCCC5)n2)ccc1-n1cnc(C)c1.COc1nc(-c2csc(Nc3cc(C4(C(F)(F)F)CC4)nn3C)n2)ccc1-n1cnc(C)c1.

What is the InChIKey of N-(2-ethyl-5,6-dihydro-4H-cyclopenta[c]pyrazol-3-yl)-4-[6-methoxy-5-(4-methylimidazol-1-yl)-2-pyridinyl]-1,3-thiazol-2-amine;N-(2-ethyl-6,6-dimethyl-4,5-dihydrocyclopenta[c]pyrazol-3-yl)-4-[6-methoxy-5-(4-methylimidazol-1-yl)-2-pyridinyl]-1,3-thiazol-2-amine;N-(2-ethyl-4,5,6,7-tetrahydroindazol-3-yl)-4-[6-methoxy-5-(4-methylimidazol-1-yl)-2-pyridinyl]-5-methyl-1,3-thiazol-2-amine;2-(3,4,7,8,9,10-hexahydro-2H-pyrimido[1,2-b]indazol-1-yl)-4-[6-methoxy-5-(4-methylimidazol-1-yl)-2-pyridinyl]-1,3-thiazole;4-[6-methoxy-5-(4-methylimidazol-1-yl)-2-pyridinyl]-N-[1-methyl-3-[1-(trifluoromethyl)cyclopropyl]pyrazol-5-yl]-1,3-thiazol-2-amine?

The InChIKey is BBHDIZIFHZSEAF-UHFFFAOYSA-N. The full InChI is InChI=1S/C23H25N7OS.2C23H27N7OS.C21H20F3N7OS.C21H23N7OS/c1-15-12-28(14-24-15)20-9-8-18(25-21(20)31-2)19-13-32-23(26-19)29-10-5-11-30-22(29)16-6-3-4-7-17(16)27-30;1-6-30-20(15-9-10-23(3,4)19(15)28-30)27-22-26-17(12-32-22)16-7-8-18(21(25-16)31-5)29-11-14(2)24-13-29;1-5-30-21(16-8-6-7-9-17(16)28-30)27-23-26-20(15(3)32-23)18-10-11-19(22(25-18)31-4)29-12-14(2)24-13-29;1-12-9-31(11-25-12)15-5-4-13(26-18(15)32-3)14-10-33-19(27-14)28-17-8-16(29-30(17)2)20(6-7-20)21(22,23)24;1-4-28-19(14-6-5-7-15(14)26-28)25-21-24-17(11-30-21)16-8-9-18(20(23-16)29-3)27-10-13(2)22-12-27/h8-9,12-14H,3-7,10-11H2,1-2H3;7-8,11-13H,6,9-10H2,1-5H3,(H,26,27);10-13H,5-9H2,1-4H3,(H,26,27);4-5,8-11H,6-7H2,1-3H3,(H,27,28);8-12H,4-7H2,1-3H3,(H,24,25).

What are the key properties of N-(2-ethyl-5,6-dihydro-4H-cyclopenta[c]pyrazol-3-yl)-4-[6-methoxy-5-(4-methylimidazol-1-yl)-2-pyridinyl]-1,3-thiazol-2-amine;N-(2-ethyl-6,6-dimethyl-4,5-dihydrocyclopenta[c]pyrazol-3-yl)-4-[6-methoxy-5-(4-methylimidazol-1-yl)-2-pyridinyl]-1,3-thiazol-2-amine;N-(2-ethyl-4,5,6,7-tetrahydroindazol-3-yl)-4-[6-methoxy-5-(4-methylimidazol-1-yl)-2-pyridinyl]-5-methyl-1,3-thiazol-2-amine;2-(3,4,7,8,9,10-hexahydro-2H-pyrimido[1,2-b]indazol-1-yl)-4-[6-methoxy-5-(4-methylimidazol-1-yl)-2-pyridinyl]-1,3-thiazole;4-[6-methoxy-5-(4-methylimidazol-1-yl)-2-pyridinyl]-N-[1-methyl-3-[1-(trifluoromethyl)cyclopropyl]pyrazol-5-yl]-1,3-thiazol-2-amine?

N-(2-ethyl-5,6-dihydro-4H-cyclopenta[c]pyrazol-3-yl)-4-[6-methoxy-5-(4-methylimidazol-1-yl)-2-pyridinyl]-1,3-thiazol-2-amine;N-(2-ethyl-6,6-dimethyl-4,5-dihydrocyclopenta[c]pyrazol-3-yl)-4-[6-methoxy-5-(4-methylimidazol-1-yl)-2-pyridinyl]-1,3-thiazol-2-amine;N-(2-ethyl-4,5,6,7-tetrahydroindazol-3-yl)-4-[6-methoxy-5-(4-methylimidazol-1-yl)-2-pyridinyl]-5-methyl-1,3-thiazol-2-amine;2-(3,4,7,8,9,10-hexahydro-2H-pyrimido[1,2-b]indazol-1-yl)-4-[6-methoxy-5-(4-methylimidazol-1-yl)-2-pyridinyl]-1,3-thiazole;4-[6-methoxy-5-(4-methylimidazol-1-yl)-2-pyridinyl]-N-[1-methyl-3-[1-(trifluoromethyl)cyclopropyl]pyrazol-5-yl]-1,3-thiazol-2-amine has a molecular weight of 2243.77 g/mol, XLogP of 23.01, 28 rotatable bonds, 4 hydrogen bond donors, and 45 hydrogen bond acceptors.

Where does this data come from?

All data for N-(2-ethyl-5,6-dihydro-4H-cyclopenta[c]pyrazol-3-yl)-4-[6-methoxy-5-(4-methylimidazol-1-yl)-2-pyridinyl]-1,3-thiazol-2-amine;N-(2-ethyl-6,6-dimethyl-4,5-dihydrocyclopenta[c]pyrazol-3-yl)-4-[6-methoxy-5-(4-methylimidazol-1-yl)-2-pyridinyl]-1,3-thiazol-2-amine;N-(2-ethyl-4,5,6,7-tetrahydroindazol-3-yl)-4-[6-methoxy-5-(4-methylimidazol-1-yl)-2-pyridinyl]-5-methyl-1,3-thiazol-2-amine;2-(3,4,7,8,9,10-hexahydro-2H-pyrimido[1,2-b]indazol-1-yl)-4-[6-methoxy-5-(4-methylimidazol-1-yl)-2-pyridinyl]-1,3-thiazole;4-[6-methoxy-5-(4-methylimidazol-1-yl)-2-pyridinyl]-N-[1-methyl-3-[1-(trifluoromethyl)cyclopropyl]pyrazol-5-yl]-1,3-thiazol-2-amine is sourced from PubChem (CID 157295405), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).