8-(1,1-dimethyl-3-oxo-2,4-dihydronaphthalen-2-yl)-6-(N-methylanilino)-2-(4-piperidin-3-yloxyanilino)pyrido[2,3-d]pyrimidin-7-one;8-(3,3-dimethyl-4-oxo-1,2-dihydronaphthalen-2-yl)-2-[4-(4-methylmorpholin-3-yl)oxyanilino]-6-(1-phenylethenyl)pyrido[2,3-d]pyrimidin-7-one;8-(3,3-dimethyl-1-oxo-2,4-dihydronaphthalen-2-yl)-6-(1-methylpiperidin-2-yl)-2-[4-[(1-methylpyrrolidin-3-yl)amino]anilino]pyrido[2,3-d]pyrimidin-7-one;8-(2,2-dimethyl-4-oxo-1,3-dihydroquinolin-3-yl)-6-(2-methylphenoxy)-2-(4-piperidin-4-yloxyanilino)pyrido[2,3-d]pyrimidin-7-one

C147H154N24O13 — CID 157312796

About 8-(1,1-dimethyl-3-oxo-2,4-dihydronaphthalen-2-yl)-6-(N-methylanilino)-2-(4-piperidin-3-yloxyanilino)pyrido[2,3-d]pyrimidin-7-one;8-(3,3-dimethyl-4-oxo-1,2-dihydronaphthalen-2-yl)-2-[4-(4-methylmorpholin-3-yl)oxyanilino]-6-(1-phenylethenyl)pyrido[2,3-d]pyrimidin-7-one;8-(3,3-dimethyl-1-oxo-2,4-dihydronaphthalen-2-yl)-6-(1-methylpiperidin-2-yl)-2-[4-[(1-methylpyrrolidin-3-yl)amino]anilino]pyrido[2,3-d]pyrimidin-7-one;8-(2,2-dimethyl-4-oxo-1,3-dihydroquinolin-3-yl)-6-(2-methylphenoxy)-2-(4-piperidin-4-yloxyanilino)pyrido[2,3-d]pyrimidin-7-one

8-(1,1-dimethyl-3-oxo-2,4-dihydronaphthalen-2-yl)-6-(N-methylanilino)-2-(4-piperidin-3-yloxyanilino)pyrido[2,3-d]pyrimidin-7-one;8-(3,3-dimethyl-4-oxo-1,2-dihydronaphthalen-2-yl)-2-[4-(4-methylmorpholin-3-yl)oxyanilino]-6-(1-phenylethenyl)pyrido[2,3-d]pyrimidin-7-one;8-(3,3-dimethyl-1-oxo-2,4-dihydronaphthalen-2-yl)-6-(1-methylpiperidin-2-yl)-2-[4-[(1-methylpyrrolidin-3-yl)amino]anilino]pyrido[2,3-d]pyrimidin-7-one;8-(2,2-dimethyl-4-oxo-1,3-dihydroquinolin-3-yl)-6-(2-methylphenoxy)-2-(4-piperidin-4-yloxyanilino)pyrido[2,3-d]pyrimidin-7-one (PubChem CID 157312796) has the molecular formula C147H154N24O13 and a molecular weight of 2465.00 g/mol. Its IUPAC name is 8-(1,1-dimethyl-3-oxo-2,4-dihydronaphthalen-2-yl)-6-(N-methylanilino)-2-(4-piperidin-3-yloxyanilino)pyrido[2,3-d]pyrimidin-7-one;8-(3,3-dimethyl-4-oxo-1,2-dihydronaphthalen-2-yl)-2-[4-(4-methylmorpholin-3-yl)oxyanilino]-6-(1-phenylethenyl)pyrido[2,3-d]pyrimidin-7-one;8-(3,3-dimethyl-1-oxo-2,4-dihydronaphthalen-2-yl)-6-(1-methylpiperidin-2-yl)-2-[4-[(1-methylpyrrolidin-3-yl)amino]anilino]pyrido[2,3-d]pyrimidin-7-one;8-(2,2-dimethyl-4-oxo-1,3-dihydroquinolin-3-yl)-6-(2-methylphenoxy)-2-(4-piperidin-4-yloxyanilino)pyrido[2,3-d]pyrimidin-7-one.

Molecular Properties

• Compound Name: 8-(1,1-dimethyl-3-oxo-2,4-dihydronaphthalen-2-yl)-6-(N-methylanilino)-2-(4-piperidin-3-yloxyanilino)pyrido[2,3-d]pyrimidin-7-one;8-(3,3-dimethyl-4-oxo-1,2-dihydronaphthalen-2-yl)-2-[4-(4-methylmorpholin-3-yl)oxyanilino]-6-(1-phenylethenyl)pyrido[2,3-d]pyrimidin-7-one;8-(3,3-dimethyl-1-oxo-2,4-dihydronaphthalen-2-yl)-6-(1-methylpiperidin-2-yl)-2-[4-[(1-methylpyrrolidin-3-yl)amino]anilino]pyrido[2,3-d]pyrimidin-7-one;8-(2,2-dimethyl-4-oxo-1,3-dihydroquinolin-3-yl)-6-(2-methylphenoxy)-2-(4-piperidin-4-yloxyanilino)pyrido[2,3-d]pyrimidin-7-one
• PubChem CID: 157312796
• Molecular Formula: C147H154N24O13
• Molecular Weight: 2465.00 g/mol
• Exact Mass: 2463.21
• IUPAC Name: 8-(1,1-dimethyl-3-oxo-2,4-dihydronaphthalen-2-yl)-6-(N-methylanilino)-2-(4-piperidin-3-yloxyanilino)pyrido[2,3-d]pyrimidin-7-one;8-(3,3-dimethyl-4-oxo-1,2-dihydronaphthalen-2-yl)-2-[4-(4-methylmorpholin-3-yl)oxyanilino]-6-(1-phenylethenyl)pyrido[2,3-d]pyrimidin-7-one;8-(3,3-dimethyl-1-oxo-2,4-dihydronaphthalen-2-yl)-6-(1-methylpiperidin-2-yl)-2-[4-[(1-methylpyrrolidin-3-yl)amino]anilino]pyrido[2,3-d]pyrimidin-7-one;8-(2,2-dimethyl-4-oxo-1,3-dihydroquinolin-3-yl)-6-(2-methylphenoxy)-2-(4-piperidin-4-yloxyanilino)pyrido[2,3-d]pyrimidin-7-one
• SMILES: C=C(c1ccccc1)c1cc2cnc(Nc3ccc(OC4COCCN4C)cc3)nc2n(C2Cc3ccccc3C(=O)C2(C)C)c1=O.CN(c1ccccc1)c1cc2cnc(Nc3ccc(OC4CCCNC4)cc3)nc2n(C2C(=O)Cc3ccccc3C2(C)C)c1=O.CN1CCC(Nc2ccc(Nc3ncc4cc(C5CCCCN5C)c(=O)n(C5C(=O)c6ccccc6CC5(C)C)c4n3)cc2)C1.Cc1ccccc1Oc1cc2cnc(Nc3ccc(OC4CCNCC4)cc3)nc2n(C2C(=O)c3ccccc3NC2(C)C)c1=O
• InChI: InChI=1S/C38H37N5O4.C37H38N6O3.C36H43N7O2.C36H36N6O4/c1-24(25-10-6-5-7-11-25)31-20-27-22-39-37(40-28-14-16-29(17-15-28)47-33-23-46-19-18-42(33)4)41-35(27)43(36(31)45)32-21-26-12-8-9-13-30(26)34(44)38(32,2)3;1-37(2)30-14-8-7-10-24(30)21-32(44)33(37)43-34-25(20-31(35(43)45)42(3)27-11-5-4-6-12-27)22-39-36(41-34)40-26-15-17-28(18-16-26)46-29-13-9-19-38-23-29;1-36(2)20-23-9-5-6-10-28(23)31(44)32(36)43-33-24(19-29(34(43)45)30-11-7-8-17-42(30)4)21-37-35(40-33)39-26-14-12-25(13-15-26)38-27-16-18-41(3)22-27;1-22-8-4-7-11-29(22)46-30-20-23-21-38-35(39-24-12-14-25(15-13-24)45-26-16-18-37-19-17-26)40-33(23)42(34(30)44)32-31(43)27-9-5-6-10-28(27)41-36(32,2)3/h5-17,20,22,32-33H,1,18-19,21,23H2,2-4H3,(H,39,40,41);4-8,10-12,14-18,20,22,29,33,38H,9,13,19,21,23H2,1-3H3,(H,39,40,41);5-6,9-10,12-15,19,21,27,30,32,38H,7-8,11,16-18,20,22H2,1-4H3,(H,37,39,40);4-15,20-21,26,32,37,41H,16-19H2,1-3H3,(H,38,39,40)
• InChIKey: BDFUGMUWLNTNRE-UHFFFAOYSA-N
• XLogP: 24.56
• TPSA: 414.75 Ų
• H-Bond Donors: 8
• H-Bond Acceptors: 37
• Rotatable Bonds: 27
• Heavy Atoms: 184
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2465.00
LogP ≤ 5	24.56
H-Bond Donors ≤ 5	8
H-Bond Acceptors ≤ 10	37

Frequently Asked Questions

What is the IUPAC name of 8-(1,1-dimethyl-3-oxo-2,4-dihydronaphthalen-2-yl)-6-(N-methylanilino)-2-(4-piperidin-3-yloxyanilino)pyrido[2,3-d]pyrimidin-7-one;8-(3,3-dimethyl-4-oxo-1,2-dihydronaphthalen-2-yl)-2-[4-(4-methylmorpholin-3-yl)oxyanilino]-6-(1-phenylethenyl)pyrido[2,3-d]pyrimidin-7-one;8-(3,3-dimethyl-1-oxo-2,4-dihydronaphthalen-2-yl)-6-(1-methylpiperidin-2-yl)-2-[4-[(1-methylpyrrolidin-3-yl)amino]anilino]pyrido[2,3-d]pyrimidin-7-one;8-(2,2-dimethyl-4-oxo-1,3-dihydroquinolin-3-yl)-6-(2-methylphenoxy)-2-(4-piperidin-4-yloxyanilino)pyrido[2,3-d]pyrimidin-7-one?

The IUPAC name of 8-(1,1-dimethyl-3-oxo-2,4-dihydronaphthalen-2-yl)-6-(N-methylanilino)-2-(4-piperidin-3-yloxyanilino)pyrido[2,3-d]pyrimidin-7-one;8-(3,3-dimethyl-4-oxo-1,2-dihydronaphthalen-2-yl)-2-[4-(4-methylmorpholin-3-yl)oxyanilino]-6-(1-phenylethenyl)pyrido[2,3-d]pyrimidin-7-one;8-(3,3-dimethyl-1-oxo-2,4-dihydronaphthalen-2-yl)-6-(1-methylpiperidin-2-yl)-2-[4-[(1-methylpyrrolidin-3-yl)amino]anilino]pyrido[2,3-d]pyrimidin-7-one;8-(2,2-dimethyl-4-oxo-1,3-dihydroquinolin-3-yl)-6-(2-methylphenoxy)-2-(4-piperidin-4-yloxyanilino)pyrido[2,3-d]pyrimidin-7-one (CID 157312796) is 8-(1,1-dimethyl-3-oxo-2,4-dihydronaphthalen-2-yl)-6-(N-methylanilino)-2-(4-piperidin-3-yloxyanilino)pyrido[2,3-d]pyrimidin-7-one;8-(3,3-dimethyl-4-oxo-1,2-dihydronaphthalen-2-yl)-2-[4-(4-methylmorpholin-3-yl)oxyanilino]-6-(1-phenylethenyl)pyrido[2,3-d]pyrimidin-7-one;8-(3,3-dimethyl-1-oxo-2,4-dihydronaphthalen-2-yl)-6-(1-methylpiperidin-2-yl)-2-[4-[(1-methylpyrrolidin-3-yl)amino]anilino]pyrido[2,3-d]pyrimidin-7-one;8-(2,2-dimethyl-4-oxo-1,3-dihydroquinolin-3-yl)-6-(2-methylphenoxy)-2-(4-piperidin-4-yloxyanilino)pyrido[2,3-d]pyrimidin-7-one.

What is the SMILES notation for 8-(1,1-dimethyl-3-oxo-2,4-dihydronaphthalen-2-yl)-6-(N-methylanilino)-2-(4-piperidin-3-yloxyanilino)pyrido[2,3-d]pyrimidin-7-one;8-(3,3-dimethyl-4-oxo-1,2-dihydronaphthalen-2-yl)-2-[4-(4-methylmorpholin-3-yl)oxyanilino]-6-(1-phenylethenyl)pyrido[2,3-d]pyrimidin-7-one;8-(3,3-dimethyl-1-oxo-2,4-dihydronaphthalen-2-yl)-6-(1-methylpiperidin-2-yl)-2-[4-[(1-methylpyrrolidin-3-yl)amino]anilino]pyrido[2,3-d]pyrimidin-7-one;8-(2,2-dimethyl-4-oxo-1,3-dihydroquinolin-3-yl)-6-(2-methylphenoxy)-2-(4-piperidin-4-yloxyanilino)pyrido[2,3-d]pyrimidin-7-one?

The canonical SMILES for 8-(1,1-dimethyl-3-oxo-2,4-dihydronaphthalen-2-yl)-6-(N-methylanilino)-2-(4-piperidin-3-yloxyanilino)pyrido[2,3-d]pyrimidin-7-one;8-(3,3-dimethyl-4-oxo-1,2-dihydronaphthalen-2-yl)-2-[4-(4-methylmorpholin-3-yl)oxyanilino]-6-(1-phenylethenyl)pyrido[2,3-d]pyrimidin-7-one;8-(3,3-dimethyl-1-oxo-2,4-dihydronaphthalen-2-yl)-6-(1-methylpiperidin-2-yl)-2-[4-[(1-methylpyrrolidin-3-yl)amino]anilino]pyrido[2,3-d]pyrimidin-7-one;8-(2,2-dimethyl-4-oxo-1,3-dihydroquinolin-3-yl)-6-(2-methylphenoxy)-2-(4-piperidin-4-yloxyanilino)pyrido[2,3-d]pyrimidin-7-one is C=C(c1ccccc1)c1cc2cnc(Nc3ccc(OC4COCCN4C)cc3)nc2n(C2Cc3ccccc3C(=O)C2(C)C)c1=O.CN(c1ccccc1)c1cc2cnc(Nc3ccc(OC4CCCNC4)cc3)nc2n(C2C(=O)Cc3ccccc3C2(C)C)c1=O.CN1CCC(Nc2ccc(Nc3ncc4cc(C5CCCCN5C)c(=O)n(C5C(=O)c6ccccc6CC5(C)C)c4n3)cc2)C1.Cc1ccccc1Oc1cc2cnc(Nc3ccc(OC4CCNCC4)cc3)nc2n(C2C(=O)c3ccccc3NC2(C)C)c1=O.

What is the InChIKey of 8-(1,1-dimethyl-3-oxo-2,4-dihydronaphthalen-2-yl)-6-(N-methylanilino)-2-(4-piperidin-3-yloxyanilino)pyrido[2,3-d]pyrimidin-7-one;8-(3,3-dimethyl-4-oxo-1,2-dihydronaphthalen-2-yl)-2-[4-(4-methylmorpholin-3-yl)oxyanilino]-6-(1-phenylethenyl)pyrido[2,3-d]pyrimidin-7-one;8-(3,3-dimethyl-1-oxo-2,4-dihydronaphthalen-2-yl)-6-(1-methylpiperidin-2-yl)-2-[4-[(1-methylpyrrolidin-3-yl)amino]anilino]pyrido[2,3-d]pyrimidin-7-one;8-(2,2-dimethyl-4-oxo-1,3-dihydroquinolin-3-yl)-6-(2-methylphenoxy)-2-(4-piperidin-4-yloxyanilino)pyrido[2,3-d]pyrimidin-7-one?

The InChIKey is BDFUGMUWLNTNRE-UHFFFAOYSA-N. The full InChI is InChI=1S/C38H37N5O4.C37H38N6O3.C36H43N7O2.C36H36N6O4/c1-24(25-10-6-5-7-11-25)31-20-27-22-39-37(40-28-14-16-29(17-15-28)47-33-23-46-19-18-42(33)4)41-35(27)43(36(31)45)32-21-26-12-8-9-13-30(26)34(44)38(32,2)3;1-37(2)30-14-8-7-10-24(30)21-32(44)33(37)43-34-25(20-31(35(43)45)42(3)27-11-5-4-6-12-27)22-39-36(41-34)40-26-15-17-28(18-16-26)46-29-13-9-19-38-23-29;1-36(2)20-23-9-5-6-10-28(23)31(44)32(36)43-33-24(19-29(34(43)45)30-11-7-8-17-42(30)4)21-37-35(40-33)39-26-14-12-25(13-15-26)38-27-16-18-41(3)22-27;1-22-8-4-7-11-29(22)46-30-20-23-21-38-35(39-24-12-14-25(15-13-24)45-26-16-18-37-19-17-26)40-33(23)42(34(30)44)32-31(43)27-9-5-6-10-28(27)41-36(32,2)3/h5-17,20,22,32-33H,1,18-19,21,23H2,2-4H3,(H,39,40,41);4-8,10-12,14-18,20,22,29,33,38H,9,13,19,21,23H2,1-3H3,(H,39,40,41);5-6,9-10,12-15,19,21,27,30,32,38H,7-8,11,16-18,20,22H2,1-4H3,(H,37,39,40);4-15,20-21,26,32,37,41H,16-19H2,1-3H3,(H,38,39,40).

What are the key properties of 8-(1,1-dimethyl-3-oxo-2,4-dihydronaphthalen-2-yl)-6-(N-methylanilino)-2-(4-piperidin-3-yloxyanilino)pyrido[2,3-d]pyrimidin-7-one;8-(3,3-dimethyl-4-oxo-1,2-dihydronaphthalen-2-yl)-2-[4-(4-methylmorpholin-3-yl)oxyanilino]-6-(1-phenylethenyl)pyrido[2,3-d]pyrimidin-7-one;8-(3,3-dimethyl-1-oxo-2,4-dihydronaphthalen-2-yl)-6-(1-methylpiperidin-2-yl)-2-[4-[(1-methylpyrrolidin-3-yl)amino]anilino]pyrido[2,3-d]pyrimidin-7-one;8-(2,2-dimethyl-4-oxo-1,3-dihydroquinolin-3-yl)-6-(2-methylphenoxy)-2-(4-piperidin-4-yloxyanilino)pyrido[2,3-d]pyrimidin-7-one?

8-(1,1-dimethyl-3-oxo-2,4-dihydronaphthalen-2-yl)-6-(N-methylanilino)-2-(4-piperidin-3-yloxyanilino)pyrido[2,3-d]pyrimidin-7-one;8-(3,3-dimethyl-4-oxo-1,2-dihydronaphthalen-2-yl)-2-[4-(4-methylmorpholin-3-yl)oxyanilino]-6-(1-phenylethenyl)pyrido[2,3-d]pyrimidin-7-one;8-(3,3-dimethyl-1-oxo-2,4-dihydronaphthalen-2-yl)-6-(1-methylpiperidin-2-yl)-2-[4-[(1-methylpyrrolidin-3-yl)amino]anilino]pyrido[2,3-d]pyrimidin-7-one;8-(2,2-dimethyl-4-oxo-1,3-dihydroquinolin-3-yl)-6-(2-methylphenoxy)-2-(4-piperidin-4-yloxyanilino)pyrido[2,3-d]pyrimidin-7-one has a molecular weight of 2465.00 g/mol, XLogP of 24.56, 27 rotatable bonds, 8 hydrogen bond donors, and 37 hydrogen bond acceptors.

Where does this data come from?

All data for 8-(1,1-dimethyl-3-oxo-2,4-dihydronaphthalen-2-yl)-6-(N-methylanilino)-2-(4-piperidin-3-yloxyanilino)pyrido[2,3-d]pyrimidin-7-one;8-(3,3-dimethyl-4-oxo-1,2-dihydronaphthalen-2-yl)-2-[4-(4-methylmorpholin-3-yl)oxyanilino]-6-(1-phenylethenyl)pyrido[2,3-d]pyrimidin-7-one;8-(3,3-dimethyl-1-oxo-2,4-dihydronaphthalen-2-yl)-6-(1-methylpiperidin-2-yl)-2-[4-[(1-methylpyrrolidin-3-yl)amino]anilino]pyrido[2,3-d]pyrimidin-7-one;8-(2,2-dimethyl-4-oxo-1,3-dihydroquinolin-3-yl)-6-(2-methylphenoxy)-2-(4-piperidin-4-yloxyanilino)pyrido[2,3-d]pyrimidin-7-one is sourced from PubChem (CID 157312796), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).