2-[6-(2-chloro-6-methyl-4-pyridinyl)-4-oxo-7-phenyl-1H-1,8-naphthyridin-2-yl]-N-(4-methylphenyl)acetamide;6-(2-chloro-6-methyl-4-pyridinyl)-2-(2-oxo-2-pyrrolidin-1-ylethyl)-7-phenyl-1H-1,8-naphthyridin-4-one;6-(2-chloro-6-methyl-4-pyridinyl)-3-phenacyl-7-phenyl-1H-1,8-naphthyridin-4-one;6-(2-chloro-6-methyl-4-pyridinyl)-7-phenyl-5-(1,1,1-trifluoropropan-2-yl)-1H-1,8-naphthyridin-4-one;6-(2-chloro-6-methyl-4-pyridinyl)-7-phenyl-2-(3,3,3-trifluoropropyl)-1H-1,8-naphthyridin-4-one;6-(2-chloro-6-methyl-4-pyridinyl)-7-phenyl-3-(3,3,3-trifluoropropyl)-1H-1,8-naphthyridin-4-one

C152H117Cl6F9N20O9 — CID 157315532

About 2-[6-(2-chloro-6-methyl-4-pyridinyl)-4-oxo-7-phenyl-1H-1,8-naphthyridin-2-yl]-N-(4-methylphenyl)acetamide;6-(2-chloro-6-methyl-4-pyridinyl)-2-(2-oxo-2-pyrrolidin-1-ylethyl)-7-phenyl-1H-1,8-naphthyridin-4-one;6-(2-chloro-6-methyl-4-pyridinyl)-3-phenacyl-7-phenyl-1H-1,8-naphthyridin-4-one;6-(2-chloro-6-methyl-4-pyridinyl)-7-phenyl-5-(1,1,1-trifluoropropan-2-yl)-1H-1,8-naphthyridin-4-one;6-(2-chloro-6-methyl-4-pyridinyl)-7-phenyl-2-(3,3,3-trifluoropropyl)-1H-1,8-naphthyridin-4-one;6-(2-chloro-6-methyl-4-pyridinyl)-7-phenyl-3-(3,3,3-trifluoropropyl)-1H-1,8-naphthyridin-4-one

2-[6-(2-chloro-6-methyl-4-pyridinyl)-4-oxo-7-phenyl-1H-1,8-naphthyridin-2-yl]-N-(4-methylphenyl)acetamide;6-(2-chloro-6-methyl-4-pyridinyl)-2-(2-oxo-2-pyrrolidin-1-ylethyl)-7-phenyl-1H-1,8-naphthyridin-4-one;6-(2-chloro-6-methyl-4-pyridinyl)-3-phenacyl-7-phenyl-1H-1,8-naphthyridin-4-one;6-(2-chloro-6-methyl-4-pyridinyl)-7-phenyl-5-(1,1,1-trifluoropropan-2-yl)-1H-1,8-naphthyridin-4-one;6-(2-chloro-6-methyl-4-pyridinyl)-7-phenyl-2-(3,3,3-trifluoropropyl)-1H-1,8-naphthyridin-4-one;6-(2-chloro-6-methyl-4-pyridinyl)-7-phenyl-3-(3,3,3-trifluoropropyl)-1H-1,8-naphthyridin-4-one (PubChem CID 157315532) has the molecular formula C152H117Cl6F9N20O9 and a molecular weight of 2751.44 g/mol. Its IUPAC name is 2-[6-(2-chloro-6-methyl-4-pyridinyl)-4-oxo-7-phenyl-1H-1,8-naphthyridin-2-yl]-N-(4-methylphenyl)acetamide;6-(2-chloro-6-methyl-4-pyridinyl)-2-(2-oxo-2-pyrrolidin-1-ylethyl)-7-phenyl-1H-1,8-naphthyridin-4-one;6-(2-chloro-6-methyl-4-pyridinyl)-3-phenacyl-7-phenyl-1H-1,8-naphthyridin-4-one;6-(2-chloro-6-methyl-4-pyridinyl)-7-phenyl-5-(1,1,1-trifluoropropan-2-yl)-1H-1,8-naphthyridin-4-one;6-(2-chloro-6-methyl-4-pyridinyl)-7-phenyl-2-(3,3,3-trifluoropropyl)-1H-1,8-naphthyridin-4-one;6-(2-chloro-6-methyl-4-pyridinyl)-7-phenyl-3-(3,3,3-trifluoropropyl)-1H-1,8-naphthyridin-4-one.

Molecular Properties

• Compound Name: 2-[6-(2-chloro-6-methyl-4-pyridinyl)-4-oxo-7-phenyl-1H-1,8-naphthyridin-2-yl]-N-(4-methylphenyl)acetamide;6-(2-chloro-6-methyl-4-pyridinyl)-2-(2-oxo-2-pyrrolidin-1-ylethyl)-7-phenyl-1H-1,8-naphthyridin-4-one;6-(2-chloro-6-methyl-4-pyridinyl)-3-phenacyl-7-phenyl-1H-1,8-naphthyridin-4-one;6-(2-chloro-6-methyl-4-pyridinyl)-7-phenyl-5-(1,1,1-trifluoropropan-2-yl)-1H-1,8-naphthyridin-4-one;6-(2-chloro-6-methyl-4-pyridinyl)-7-phenyl-2-(3,3,3-trifluoropropyl)-1H-1,8-naphthyridin-4-one;6-(2-chloro-6-methyl-4-pyridinyl)-7-phenyl-3-(3,3,3-trifluoropropyl)-1H-1,8-naphthyridin-4-one
• PubChem CID: 157315532
• Molecular Formula: C152H117Cl6F9N20O9
• Molecular Weight: 2751.44 g/mol
• Exact Mass: 2746.73
• IUPAC Name: 2-[6-(2-chloro-6-methyl-4-pyridinyl)-4-oxo-7-phenyl-1H-1,8-naphthyridin-2-yl]-N-(4-methylphenyl)acetamide;6-(2-chloro-6-methyl-4-pyridinyl)-2-(2-oxo-2-pyrrolidin-1-ylethyl)-7-phenyl-1H-1,8-naphthyridin-4-one;6-(2-chloro-6-methyl-4-pyridinyl)-3-phenacyl-7-phenyl-1H-1,8-naphthyridin-4-one;6-(2-chloro-6-methyl-4-pyridinyl)-7-phenyl-5-(1,1,1-trifluoropropan-2-yl)-1H-1,8-naphthyridin-4-one;6-(2-chloro-6-methyl-4-pyridinyl)-7-phenyl-2-(3,3,3-trifluoropropyl)-1H-1,8-naphthyridin-4-one;6-(2-chloro-6-methyl-4-pyridinyl)-7-phenyl-3-(3,3,3-trifluoropropyl)-1H-1,8-naphthyridin-4-one
• SMILES: Cc1cc(-c2c(-c3ccccc3)nc3[nH]ccc(=O)c3c2C(C)C(F)(F)F)cc(Cl)n1.Cc1cc(-c2cc3c(=O)c(CC(=O)c4ccccc4)c[nH]c3nc2-c2ccccc2)cc(Cl)n1.Cc1cc(-c2cc3c(=O)c(CCC(F)(F)F)c[nH]c3nc2-c2ccccc2)cc(Cl)n1.Cc1cc(-c2cc3c(=O)cc(CC(=O)N4CCCC4)[nH]c3nc2-c2ccccc2)cc(Cl)n1.Cc1cc(-c2cc3c(=O)cc(CCC(F)(F)F)[nH]c3nc2-c2ccccc2)cc(Cl)n1.Cc1ccc(NC(=O)Cc2cc(=O)c3cc(-c4cc(C)nc(Cl)c4)c(-c4ccccc4)nc3[nH]2)cc1
• InChI: InChI=1S/C29H23ClN4O2.C28H20ClN3O2.C26H23ClN4O2.3C23H17ClF3N3O/c1-17-8-10-21(11-9-17)32-27(36)15-22-14-25(35)24-16-23(20-12-18(2)31-26(30)13-20)28(34-29(24)33-22)19-6-4-3-5-7-19;1-17-12-20(14-25(29)31-17)22-15-23-27(34)21(13-24(33)18-8-4-2-5-9-18)16-30-28(23)32-26(22)19-10-6-3-7-11-19;1-16-11-18(12-23(27)28-16)20-15-21-22(32)13-19(14-24(33)31-9-5-6-10-31)29-26(21)30-25(20)17-7-3-2-4-8-17;1-12-10-15(11-17(24)29-12)19-18(13(2)23(25,26)27)20-16(31)8-9-28-22(20)30-21(19)14-6-4-3-5-7-14;1-13-9-15(10-20(24)28-13)17-12-18-19(31)11-16(7-8-23(25,26)27)29-22(18)30-21(17)14-5-3-2-4-6-14;1-13-9-16(10-19(24)29-13)17-11-18-21(31)15(7-8-23(25,26)27)12-28-22(18)30-20(17)14-5-3-2-4-6-14/h3-14,16H,15H2,1-2H3,(H,32,36)(H,33,34,35);2-12,14-16H,13H2,1H3,(H,30,32,34);2-4,7-8,11-13,15H,5-6,9-10,14H2,1H3,(H,29,30,32);3-11,13H,1-2H3,(H,28,30,31);2-6,9-12H,7-8H2,1H3,(H,29,30,31);2-6,9-12H,7-8H2,1H3,(H,28,30,31)
• InChIKey: BDNWEGBZZLELHD-UHFFFAOYSA-N
• XLogP: 35.42
• TPSA: 418.32 Ų
• H-Bond Donors: 7
• H-Bond Acceptors: 21
• Rotatable Bonds: 25
• Heavy Atoms: 196
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2751.44
LogP ≤ 5	35.42
H-Bond Donors ≤ 5	7
H-Bond Acceptors ≤ 10	21

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': '2-halo_pyridine', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of 2-[6-(2-chloro-6-methyl-4-pyridinyl)-4-oxo-7-phenyl-1H-1,8-naphthyridin-2-yl]-N-(4-methylphenyl)acetamide;6-(2-chloro-6-methyl-4-pyridinyl)-2-(2-oxo-2-pyrrolidin-1-ylethyl)-7-phenyl-1H-1,8-naphthyridin-4-one;6-(2-chloro-6-methyl-4-pyridinyl)-3-phenacyl-7-phenyl-1H-1,8-naphthyridin-4-one;6-(2-chloro-6-methyl-4-pyridinyl)-7-phenyl-5-(1,1,1-trifluoropropan-2-yl)-1H-1,8-naphthyridin-4-one;6-(2-chloro-6-methyl-4-pyridinyl)-7-phenyl-2-(3,3,3-trifluoropropyl)-1H-1,8-naphthyridin-4-one;6-(2-chloro-6-methyl-4-pyridinyl)-7-phenyl-3-(3,3,3-trifluoropropyl)-1H-1,8-naphthyridin-4-one?

The IUPAC name of 2-[6-(2-chloro-6-methyl-4-pyridinyl)-4-oxo-7-phenyl-1H-1,8-naphthyridin-2-yl]-N-(4-methylphenyl)acetamide;6-(2-chloro-6-methyl-4-pyridinyl)-2-(2-oxo-2-pyrrolidin-1-ylethyl)-7-phenyl-1H-1,8-naphthyridin-4-one;6-(2-chloro-6-methyl-4-pyridinyl)-3-phenacyl-7-phenyl-1H-1,8-naphthyridin-4-one;6-(2-chloro-6-methyl-4-pyridinyl)-7-phenyl-5-(1,1,1-trifluoropropan-2-yl)-1H-1,8-naphthyridin-4-one;6-(2-chloro-6-methyl-4-pyridinyl)-7-phenyl-2-(3,3,3-trifluoropropyl)-1H-1,8-naphthyridin-4-one;6-(2-chloro-6-methyl-4-pyridinyl)-7-phenyl-3-(3,3,3-trifluoropropyl)-1H-1,8-naphthyridin-4-one (CID 157315532) is 2-[6-(2-chloro-6-methyl-4-pyridinyl)-4-oxo-7-phenyl-1H-1,8-naphthyridin-2-yl]-N-(4-methylphenyl)acetamide;6-(2-chloro-6-methyl-4-pyridinyl)-2-(2-oxo-2-pyrrolidin-1-ylethyl)-7-phenyl-1H-1,8-naphthyridin-4-one;6-(2-chloro-6-methyl-4-pyridinyl)-3-phenacyl-7-phenyl-1H-1,8-naphthyridin-4-one;6-(2-chloro-6-methyl-4-pyridinyl)-7-phenyl-5-(1,1,1-trifluoropropan-2-yl)-1H-1,8-naphthyridin-4-one;6-(2-chloro-6-methyl-4-pyridinyl)-7-phenyl-2-(3,3,3-trifluoropropyl)-1H-1,8-naphthyridin-4-one;6-(2-chloro-6-methyl-4-pyridinyl)-7-phenyl-3-(3,3,3-trifluoropropyl)-1H-1,8-naphthyridin-4-one.

What is the SMILES notation for 2-[6-(2-chloro-6-methyl-4-pyridinyl)-4-oxo-7-phenyl-1H-1,8-naphthyridin-2-yl]-N-(4-methylphenyl)acetamide;6-(2-chloro-6-methyl-4-pyridinyl)-2-(2-oxo-2-pyrrolidin-1-ylethyl)-7-phenyl-1H-1,8-naphthyridin-4-one;6-(2-chloro-6-methyl-4-pyridinyl)-3-phenacyl-7-phenyl-1H-1,8-naphthyridin-4-one;6-(2-chloro-6-methyl-4-pyridinyl)-7-phenyl-5-(1,1,1-trifluoropropan-2-yl)-1H-1,8-naphthyridin-4-one;6-(2-chloro-6-methyl-4-pyridinyl)-7-phenyl-2-(3,3,3-trifluoropropyl)-1H-1,8-naphthyridin-4-one;6-(2-chloro-6-methyl-4-pyridinyl)-7-phenyl-3-(3,3,3-trifluoropropyl)-1H-1,8-naphthyridin-4-one?

The canonical SMILES for 2-[6-(2-chloro-6-methyl-4-pyridinyl)-4-oxo-7-phenyl-1H-1,8-naphthyridin-2-yl]-N-(4-methylphenyl)acetamide;6-(2-chloro-6-methyl-4-pyridinyl)-2-(2-oxo-2-pyrrolidin-1-ylethyl)-7-phenyl-1H-1,8-naphthyridin-4-one;6-(2-chloro-6-methyl-4-pyridinyl)-3-phenacyl-7-phenyl-1H-1,8-naphthyridin-4-one;6-(2-chloro-6-methyl-4-pyridinyl)-7-phenyl-5-(1,1,1-trifluoropropan-2-yl)-1H-1,8-naphthyridin-4-one;6-(2-chloro-6-methyl-4-pyridinyl)-7-phenyl-2-(3,3,3-trifluoropropyl)-1H-1,8-naphthyridin-4-one;6-(2-chloro-6-methyl-4-pyridinyl)-7-phenyl-3-(3,3,3-trifluoropropyl)-1H-1,8-naphthyridin-4-one is Cc1cc(-c2c(-c3ccccc3)nc3[nH]ccc(=O)c3c2C(C)C(F)(F)F)cc(Cl)n1.Cc1cc(-c2cc3c(=O)c(CC(=O)c4ccccc4)c[nH]c3nc2-c2ccccc2)cc(Cl)n1.Cc1cc(-c2cc3c(=O)c(CCC(F)(F)F)c[nH]c3nc2-c2ccccc2)cc(Cl)n1.Cc1cc(-c2cc3c(=O)cc(CC(=O)N4CCCC4)[nH]c3nc2-c2ccccc2)cc(Cl)n1.Cc1cc(-c2cc3c(=O)cc(CCC(F)(F)F)[nH]c3nc2-c2ccccc2)cc(Cl)n1.Cc1ccc(NC(=O)Cc2cc(=O)c3cc(-c4cc(C)nc(Cl)c4)c(-c4ccccc4)nc3[nH]2)cc1.

What is the InChIKey of 2-[6-(2-chloro-6-methyl-4-pyridinyl)-4-oxo-7-phenyl-1H-1,8-naphthyridin-2-yl]-N-(4-methylphenyl)acetamide;6-(2-chloro-6-methyl-4-pyridinyl)-2-(2-oxo-2-pyrrolidin-1-ylethyl)-7-phenyl-1H-1,8-naphthyridin-4-one;6-(2-chloro-6-methyl-4-pyridinyl)-3-phenacyl-7-phenyl-1H-1,8-naphthyridin-4-one;6-(2-chloro-6-methyl-4-pyridinyl)-7-phenyl-5-(1,1,1-trifluoropropan-2-yl)-1H-1,8-naphthyridin-4-one;6-(2-chloro-6-methyl-4-pyridinyl)-7-phenyl-2-(3,3,3-trifluoropropyl)-1H-1,8-naphthyridin-4-one;6-(2-chloro-6-methyl-4-pyridinyl)-7-phenyl-3-(3,3,3-trifluoropropyl)-1H-1,8-naphthyridin-4-one?

The InChIKey is BDNWEGBZZLELHD-UHFFFAOYSA-N. The full InChI is InChI=1S/C29H23ClN4O2.C28H20ClN3O2.C26H23ClN4O2.3C23H17ClF3N3O/c1-17-8-10-21(11-9-17)32-27(36)15-22-14-25(35)24-16-23(20-12-18(2)31-26(30)13-20)28(34-29(24)33-22)19-6-4-3-5-7-19;1-17-12-20(14-25(29)31-17)22-15-23-27(34)21(13-24(33)18-8-4-2-5-9-18)16-30-28(23)32-26(22)19-10-6-3-7-11-19;1-16-11-18(12-23(27)28-16)20-15-21-22(32)13-19(14-24(33)31-9-5-6-10-31)29-26(21)30-25(20)17-7-3-2-4-8-17;1-12-10-15(11-17(24)29-12)19-18(13(2)23(25,26)27)20-16(31)8-9-28-22(20)30-21(19)14-6-4-3-5-7-14;1-13-9-15(10-20(24)28-13)17-12-18-19(31)11-16(7-8-23(25,26)27)29-22(18)30-21(17)14-5-3-2-4-6-14;1-13-9-16(10-19(24)29-13)17-11-18-21(31)15(7-8-23(25,26)27)12-28-22(18)30-20(17)14-5-3-2-4-6-14/h3-14,16H,15H2,1-2H3,(H,32,36)(H,33,34,35);2-12,14-16H,13H2,1H3,(H,30,32,34);2-4,7-8,11-13,15H,5-6,9-10,14H2,1H3,(H,29,30,32);3-11,13H,1-2H3,(H,28,30,31);2-6,9-12H,7-8H2,1H3,(H,29,30,31);2-6,9-12H,7-8H2,1H3,(H,28,30,31).

What are the key properties of 2-[6-(2-chloro-6-methyl-4-pyridinyl)-4-oxo-7-phenyl-1H-1,8-naphthyridin-2-yl]-N-(4-methylphenyl)acetamide;6-(2-chloro-6-methyl-4-pyridinyl)-2-(2-oxo-2-pyrrolidin-1-ylethyl)-7-phenyl-1H-1,8-naphthyridin-4-one;6-(2-chloro-6-methyl-4-pyridinyl)-3-phenacyl-7-phenyl-1H-1,8-naphthyridin-4-one;6-(2-chloro-6-methyl-4-pyridinyl)-7-phenyl-5-(1,1,1-trifluoropropan-2-yl)-1H-1,8-naphthyridin-4-one;6-(2-chloro-6-methyl-4-pyridinyl)-7-phenyl-2-(3,3,3-trifluoropropyl)-1H-1,8-naphthyridin-4-one;6-(2-chloro-6-methyl-4-pyridinyl)-7-phenyl-3-(3,3,3-trifluoropropyl)-1H-1,8-naphthyridin-4-one?

2-[6-(2-chloro-6-methyl-4-pyridinyl)-4-oxo-7-phenyl-1H-1,8-naphthyridin-2-yl]-N-(4-methylphenyl)acetamide;6-(2-chloro-6-methyl-4-pyridinyl)-2-(2-oxo-2-pyrrolidin-1-ylethyl)-7-phenyl-1H-1,8-naphthyridin-4-one;6-(2-chloro-6-methyl-4-pyridinyl)-3-phenacyl-7-phenyl-1H-1,8-naphthyridin-4-one;6-(2-chloro-6-methyl-4-pyridinyl)-7-phenyl-5-(1,1,1-trifluoropropan-2-yl)-1H-1,8-naphthyridin-4-one;6-(2-chloro-6-methyl-4-pyridinyl)-7-phenyl-2-(3,3,3-trifluoropropyl)-1H-1,8-naphthyridin-4-one;6-(2-chloro-6-methyl-4-pyridinyl)-7-phenyl-3-(3,3,3-trifluoropropyl)-1H-1,8-naphthyridin-4-one has a molecular weight of 2751.44 g/mol, XLogP of 35.42, 25 rotatable bonds, 7 hydrogen bond donors, and 21 hydrogen bond acceptors.

Where does this data come from?

All data for 2-[6-(2-chloro-6-methyl-4-pyridinyl)-4-oxo-7-phenyl-1H-1,8-naphthyridin-2-yl]-N-(4-methylphenyl)acetamide;6-(2-chloro-6-methyl-4-pyridinyl)-2-(2-oxo-2-pyrrolidin-1-ylethyl)-7-phenyl-1H-1,8-naphthyridin-4-one;6-(2-chloro-6-methyl-4-pyridinyl)-3-phenacyl-7-phenyl-1H-1,8-naphthyridin-4-one;6-(2-chloro-6-methyl-4-pyridinyl)-7-phenyl-5-(1,1,1-trifluoropropan-2-yl)-1H-1,8-naphthyridin-4-one;6-(2-chloro-6-methyl-4-pyridinyl)-7-phenyl-2-(3,3,3-trifluoropropyl)-1H-1,8-naphthyridin-4-one;6-(2-chloro-6-methyl-4-pyridinyl)-7-phenyl-3-(3,3,3-trifluoropropyl)-1H-1,8-naphthyridin-4-one is sourced from PubChem (CID 157315532), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).