4-[6-methoxy-5-(methylsulfonylmethyl)-3-pyridinyl]-6-methyl-7-[(4-methylsulfonylpiperazin-1-yl)methyl]-2-piperidin-1-ylthieno[3,2-d]pyrimidine;4-[[4-[6-methoxy-5-(methylsulfonylmethyl)-3-pyridinyl]-2-piperidin-1-ylthieno[3,2-d]pyrimidin-7-yl]methyl]-N-(2,2,2-trifluoroethyl)piperazine-1-carboxamide;4-[6-methoxy-5-(methylsulfonylmethyl)-3-pyridinyl]-2-piperidin-1-yl-7-[[4-(2,2,2-trifluoroethyl)piperazin-1-yl]methyl]thieno[3,2-d]pyrimidine;2,2,2-trifluoro-1-[4-[[4-[6-methoxy-5-(methylsulfonylmethyl)-3-pyridinyl]-2-piperidin-1-ylthieno[3,2-d]pyrimidin-7-yl]methyl]piperazin-1-yl]ethanone

C105H134F9N25O16S9 — CID 157320862

IUPAC4-[6-methoxy-5-(methylsulfonylmethyl)-3-pyridinyl]-6-methyl-7-[(4-methylsulfonylpiperazin-1-yl)methyl]-2-piperidin-1-ylthieno[3,2-d]pyrimidine;4-[[4-[6-methoxy-5-(methylsulfonylmethyl)-3-pyridinyl]-2-piperidin-1-ylthieno[3,2-d]pyrimidin-7-yl]methyl]-N-(2,2,2-trifluoroethyl)piperazine-1-carboxamide;4-[6-methoxy-5-(methylsulfonylmethyl)-3-pyridinyl]-2-piperidin-1-yl-7-[[4-(2,2,2-trifluoroethyl)piperazin-1-yl]methyl]thieno[3,2-d]pyrimidine;2,2,2-trifluoro-1-[4-[[4-[6-methoxy-5-(methylsulfonylmethyl)-3-pyridinyl]-2-piperidin-1-ylthieno[3,2-d]pyrimidin-7-yl]methyl]piperazin-1-yl]ethanone
SMILESCOc1ncc(-c2nc(N3CCCCC3)nc3c(CN4CCN(C(=O)C(F)(F)F)CC4)csc23)cc1CS(C)(=O)=O.COc1ncc(-c2nc(N3CCCCC3)nc3c(CN4CCN(C(=O)NCC(F)(F)F)CC4)csc23)cc1CS(C)(=O)=O.COc1ncc(-c2nc(N3CCCCC3)nc3c(CN4CCN(CC(F)(F)F)CC4)csc23)cc1CS(C)(=O)=O.COc1ncc(-c2nc(N3CCCCC3)nc3c(CN4CCN(S(C)(=O)=O)CC4)c(C)sc23)cc1CS(C)(=O)=O
InChIInChI=1S/C27H34F3N7O4S2.C26H31F3N6O4S2.C26H33F3N6O3S2.C26H36N6O5S3/c1-41-24-19(16-43(2,39)40)12-18(13-31-24)21-23-22(34-25(33-21)36-6-4-3-5-7-36)20(15-42-23)14-35-8-10-37(11-9-35)26(38)32-17-27(28,29)30;1-39-23-18(16-41(2,37)38)12-17(13-30-23)20-22-21(32-25(31-20)35-6-4-3-5-7-35)19(15-40-22)14-33-8-10-34(11-9-33)24(36)26(27,28)29;1-38-24-19(16-40(2,36)37)12-18(13-30-24)21-23-22(32-25(31-21)35-6-4-3-5-7-35)20(15-39-23)14-33-8-10-34(11-9-33)17-26(27,28)29;1-18-21(16-30-10-12-32(13-11-30)40(4,35)36)23-24(38-18)22(28-26(29-23)31-8-6-5-7-9-31)19-14-20(17-39(3,33)34)25(37-2)27-15-19/h12-13,15H,3-11,14,16-17H2,1-2H3,(H,32,38);12-13,15H,3-11,14,16H2,1-2H3;12-13,15H,3-11,14,16-17H2,1-2H3;14-15H,5-13,16-17H2,1-4H3
InChIKeyBEDKAEDEQWOTAD-UHFFFAOYSA-N
MW2461.97 g/mol
LogP13.85
Rot. Bonds31

About 4-[6-methoxy-5-(methylsulfonylmethyl)-3-pyridinyl]-6-methyl-7-[(4-methylsulfonylpiperazin-1-yl)methyl]-2-piperidin-1-ylthieno[3,2-d]pyrimidine;4-[[4-[6-methoxy-5-(methylsulfonylmethyl)-3-pyridinyl]-2-piperidin-1-ylthieno[3,2-d]pyrimidin-7-yl]methyl]-N-(2,2,2-trifluoroethyl)piperazine-1-carboxamide;4-[6-methoxy-5-(methylsulfonylmethyl)-3-pyridinyl]-2-piperidin-1-yl-7-[[4-(2,2,2-trifluoroethyl)piperazin-1-yl]methyl]thieno[3,2-d]pyrimidine;2,2,2-trifluoro-1-[4-[[4-[6-methoxy-5-(methylsulfonylmethyl)-3-pyridinyl]-2-piperidin-1-ylthieno[3,2-d]pyrimidin-7-yl]methyl]piperazin-1-yl]ethanone

4-[6-methoxy-5-(methylsulfonylmethyl)-3-pyridinyl]-6-methyl-7-[(4-methylsulfonylpiperazin-1-yl)methyl]-2-piperidin-1-ylthieno[3,2-d]pyrimidine;4-[[4-[6-methoxy-5-(methylsulfonylmethyl)-3-pyridinyl]-2-piperidin-1-ylthieno[3,2-d]pyrimidin-7-yl]methyl]-N-(2,2,2-trifluoroethyl)piperazine-1-carboxamide;4-[6-methoxy-5-(methylsulfonylmethyl)-3-pyridinyl]-2-piperidin-1-yl-7-[[4-(2,2,2-trifluoroethyl)piperazin-1-yl]methyl]thieno[3,2-d]pyrimidine;2,2,2-trifluoro-1-[4-[[4-[6-methoxy-5-(methylsulfonylmethyl)-3-pyridinyl]-2-piperidin-1-ylthieno[3,2-d]pyrimidin-7-yl]methyl]piperazin-1-yl]ethanone (PubChem CID 157320862) has the molecular formula C105H134F9N25O16S9 and a molecular weight of 2461.97 g/mol. Its IUPAC name is 4-[6-methoxy-5-(methylsulfonylmethyl)-3-pyridinyl]-6-methyl-7-[(4-methylsulfonylpiperazin-1-yl)methyl]-2-piperidin-1-ylthieno[3,2-d]pyrimidine;4-[[4-[6-methoxy-5-(methylsulfonylmethyl)-3-pyridinyl]-2-piperidin-1-ylthieno[3,2-d]pyrimidin-7-yl]methyl]-N-(2,2,2-trifluoroethyl)piperazine-1-carboxamide;4-[6-methoxy-5-(methylsulfonylmethyl)-3-pyridinyl]-2-piperidin-1-yl-7-[[4-(2,2,2-trifluoroethyl)piperazin-1-yl]methyl]thieno[3,2-d]pyrimidine;2,2,2-trifluoro-1-[4-[[4-[6-methoxy-5-(methylsulfonylmethyl)-3-pyridinyl]-2-piperidin-1-ylthieno[3,2-d]pyrimidin-7-yl]methyl]piperazin-1-yl]ethanone.

Molecular Properties

Compound Name4-[6-methoxy-5-(methylsulfonylmethyl)-3-pyridinyl]-6-methyl-7-[(4-methylsulfonylpiperazin-1-yl)methyl]-2-piperidin-1-ylthieno[3,2-d]pyrimidine;4-[[4-[6-methoxy-5-(methylsulfonylmethyl)-3-pyridinyl]-2-piperidin-1-ylthieno[3,2-d]pyrimidin-7-yl]methyl]-N-(2,2,2-trifluoroethyl)piperazine-1-carboxamide;4-[6-methoxy-5-(methylsulfonylmethyl)-3-pyridinyl]-2-piperidin-1-yl-7-[[4-(2,2,2-trifluoroethyl)piperazin-1-yl]methyl]thieno[3,2-d]pyrimidine;2,2,2-trifluoro-1-[4-[[4-[6-methoxy-5-(methylsulfonylmethyl)-3-pyridinyl]-2-piperidin-1-ylthieno[3,2-d]pyrimidin-7-yl]methyl]piperazin-1-yl]ethanone
PubChem CID157320862
Molecular FormulaC105H134F9N25O16S9
Molecular Weight2461.97 g/mol
Exact Mass2459.78
IUPAC Name4-[6-methoxy-5-(methylsulfonylmethyl)-3-pyridinyl]-6-methyl-7-[(4-methylsulfonylpiperazin-1-yl)methyl]-2-piperidin-1-ylthieno[3,2-d]pyrimidine;4-[[4-[6-methoxy-5-(methylsulfonylmethyl)-3-pyridinyl]-2-piperidin-1-ylthieno[3,2-d]pyrimidin-7-yl]methyl]-N-(2,2,2-trifluoroethyl)piperazine-1-carboxamide;4-[6-methoxy-5-(methylsulfonylmethyl)-3-pyridinyl]-2-piperidin-1-yl-7-[[4-(2,2,2-trifluoroethyl)piperazin-1-yl]methyl]thieno[3,2-d]pyrimidine;2,2,2-trifluoro-1-[4-[[4-[6-methoxy-5-(methylsulfonylmethyl)-3-pyridinyl]-2-piperidin-1-ylthieno[3,2-d]pyrimidin-7-yl]methyl]piperazin-1-yl]ethanone
SMILESCOc1ncc(-c2nc(N3CCCCC3)nc3c(CN4CCN(C(=O)C(F)(F)F)CC4)csc23)cc1CS(C)(=O)=O.COc1ncc(-c2nc(N3CCCCC3)nc3c(CN4CCN(C(=O)NCC(F)(F)F)CC4)csc23)cc1CS(C)(=O)=O.COc1ncc(-c2nc(N3CCCCC3)nc3c(CN4CCN(CC(F)(F)F)CC4)csc23)cc1CS(C)(=O)=O.COc1ncc(-c2nc(N3CCCCC3)nc3c(CN4CCN(S(C)(=O)=O)CC4)c(C)sc23)cc1CS(C)(=O)=O
InChIInChI=1S/C27H34F3N7O4S2.C26H31F3N6O4S2.C26H33F3N6O3S2.C26H36N6O5S3/c1-41-24-19(16-43(2,39)40)12-18(13-31-24)21-23-22(34-25(33-21)36-6-4-3-5-7-36)20(15-42-23)14-35-8-10-37(11-9-35)26(38)32-17-27(28,29)30;1-39-23-18(16-41(2,37)38)12-17(13-30-23)20-22-21(32-25(31-20)35-6-4-3-5-7-35)19(15-40-22)14-33-8-10-34(11-9-33)24(36)26(27,28)29;1-38-24-19(16-40(2,36)37)12-18(13-30-24)21-23-22(32-25(31-21)35-6-4-3-5-7-35)20(15-39-23)14-33-8-10-34(11-9-33)17-26(27,28)29;1-18-21(16-30-10-12-32(13-11-30)40(4,35)36)23-24(38-18)22(28-26(29-23)31-8-6-5-7-9-31)19-14-20(17-39(3,33)34)25(37-2)27-15-19/h12-13,15H,3-11,14,16-17H2,1-2H3,(H,32,38);12-13,15H,3-11,14,16H2,1-2H3;12-13,15H,3-11,14,16-17H2,1-2H3;14-15H,5-13,16-17H2,1-4H3
InChIKeyBEDKAEDEQWOTAD-UHFFFAOYSA-N
XLogP13.85
TPSA447.35 Ų
H-Bond Donors1
H-Bond Acceptors41
Rotatable Bonds31
Heavy Atoms164
Complexity—

Lipinski Rule of Five

3 violations

RuleValue
MW ≤ 5002461.97
LogP ≤ 513.85
H-Bond Donors ≤ 51
H-Bond Acceptors ≤ 1041

Analyze 4-[6-methoxy-5-(methylsulfonylmethyl)-3-pyridinyl]-6-methyl-7-[(4-methylsulfonylpiperazin-1-yl)methyl]-2-piperidin-1-ylthieno[3,2-d]pyrimidine;4-[[4-[6-methoxy-5-(methylsulfonylmethyl)-3-pyridinyl]-2-piperidin-1-ylthieno[3,2-d]pyrimidin-7-yl]methyl]-N-(2,2,2-trifluoroethyl)piperazine-1-carboxamide;4-[6-methoxy-5-(methylsulfonylmethyl)-3-pyridinyl]-2-piperidin-1-yl-7-[[4-(2,2,2-trifluoroethyl)piperazin-1-yl]methyl]thieno[3,2-d]pyrimidine;2,2,2-trifluoro-1-[4-[[4-[6-methoxy-5-(methylsulfonylmethyl)-3-pyridinyl]-2-piperidin-1-ylthieno[3,2-d]pyrimidin-7-yl]methyl]piperazin-1-yl]ethanone with MolForge

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Related Compounds

N-[5-[7-[[4-(4-fluoropiperidin-1-yl)piperidin-1-yl]methyl]-6-methyl-2-morpholin-4-ylthieno[3,2-d]pyrimidin-4-yl]-2-methoxy-3-pyridinyl]methanesulfonamide
CID 122427967
N-[5-[7-[(3,3-difluoro-4-pyrrolidin-1-ylpiperidin-1-yl)methyl]-6-methyl-2-morpholin-4-ylthieno[3,2-d]pyrimidin-4-yl]-2-methoxypyridin-3-yl]methanesulfonamide
CID 122428071
4-[[4-[5-(methanesulfonamido)-6-methoxypyridin-3-yl]-2-morpholin-4-ylthieno[3,2-d]pyrimidin-7-yl]methyl]-N-(2,2,2-trifluoroethyl)piperazine-1-carboxamide
CID 122432278
N-[2-methoxy-5-[6-methyl-2-morpholin-4-yl-7-[[4-(2,2,2-trifluoroethyl)piperazin-1-yl]methyl]thieno[3,2-d]pyrimidin-4-yl]pyridin-3-yl]cyclopropanesulfonamide
CID 122432282
N-[2-methoxy-5-[2-morpholin-4-yl-7-[[4-(2,2,2-trifluoroacetyl)piperazin-1-yl]methyl]thieno[3,2-d]pyrimidin-4-yl]pyridin-3-yl]methanesulfonamide
CID 122432291
N-[2-methoxy-5-[6-methyl-2-morpholin-4-yl-7-[[4-(2,2,2-trifluoroacetyl)piperazin-1-yl]methyl]thieno[3,2-d]pyrimidin-4-yl]pyridin-3-yl]cyclopropanesulfonamide
CID 122432314
N-[2-methoxy-5-[6-methyl-2-morpholin-4-yl-7-[[4-(2,2,2-trifluoroacetyl)piperazin-1-yl]methyl]thieno[3,2-d]pyrimidin-4-yl]pyridin-3-yl]methanesulfonamide
CID 122432340
N-[2-methoxy-5-[6-methyl-2-morpholin-4-yl-7-[[4-[(2S)-2-(trifluoromethyl)pyrrolidin-1-yl]piperidin-1-yl]methyl]thieno[3,2-d]pyrimidin-4-yl]pyridin-3-yl]methanesulfonamide
CID 122432348
1-[[4-[5-(methanesulfonamido)-6-methoxypyridin-3-yl]-2-morpholin-4-ylthieno[3,2-d]pyrimidin-7-yl]methyl]-N-(2,2,2-trifluoroethyl)piperidine-4-carboxamide
CID 122432504
N-[2-methoxy-5-[6-methyl-2-morpholin-4-yl-7-[[4-(2,2,2-trifluoroethyl)piperazin-1-yl]methyl]thieno[3,2-d]pyrimidin-4-yl]pyridin-3-yl]methanesulfonamide
CID 122432511
N-[5-[7-[(4-acetylpiperazin-1-yl)methyl]-2-morpholin-4-ylthieno[3,2-d]pyrimidin-4-yl]-2-methoxy-3-pyridinyl]methanesulfonamide
CID 122427951
N-[2-methoxy-5-[7-[[4-(1-methylpiperidin-4-yl)piperazin-1-yl]methyl]-2-morpholin-4-ylthieno[3,2-d]pyrimidin-4-yl]-3-pyridinyl]methanesulfonamide
CID 122428062

Frequently Asked Questions

What is the IUPAC name of 4-[6-methoxy-5-(methylsulfonylmethyl)-3-pyridinyl]-6-methyl-7-[(4-methylsulfonylpiperazin-1-yl)methyl]-2-piperidin-1-ylthieno[3,2-d]pyrimidine;4-[[4-[6-methoxy-5-(methylsulfonylmethyl)-3-pyridinyl]-2-piperidin-1-ylthieno[3,2-d]pyrimidin-7-yl]methyl]-N-(2,2,2-trifluoroethyl)piperazine-1-carboxamide;4-[6-methoxy-5-(methylsulfonylmethyl)-3-pyridinyl]-2-piperidin-1-yl-7-[[4-(2,2,2-trifluoroethyl)piperazin-1-yl]methyl]thieno[3,2-d]pyrimidine;2,2,2-trifluoro-1-[4-[[4-[6-methoxy-5-(methylsulfonylmethyl)-3-pyridinyl]-2-piperidin-1-ylthieno[3,2-d]pyrimidin-7-yl]methyl]piperazin-1-yl]ethanone?
The IUPAC name of 4-[6-methoxy-5-(methylsulfonylmethyl)-3-pyridinyl]-6-methyl-7-[(4-methylsulfonylpiperazin-1-yl)methyl]-2-piperidin-1-ylthieno[3,2-d]pyrimidine;4-[[4-[6-methoxy-5-(methylsulfonylmethyl)-3-pyridinyl]-2-piperidin-1-ylthieno[3,2-d]pyrimidin-7-yl]methyl]-N-(2,2,2-trifluoroethyl)piperazine-1-carboxamide;4-[6-methoxy-5-(methylsulfonylmethyl)-3-pyridinyl]-2-piperidin-1-yl-7-[[4-(2,2,2-trifluoroethyl)piperazin-1-yl]methyl]thieno[3,2-d]pyrimidine;2,2,2-trifluoro-1-[4-[[4-[6-methoxy-5-(methylsulfonylmethyl)-3-pyridinyl]-2-piperidin-1-ylthieno[3,2-d]pyrimidin-7-yl]methyl]piperazin-1-yl]ethanone (CID 157320862) is 4-[6-methoxy-5-(methylsulfonylmethyl)-3-pyridinyl]-6-methyl-7-[(4-methylsulfonylpiperazin-1-yl)methyl]-2-piperidin-1-ylthieno[3,2-d]pyrimidine;4-[[4-[6-methoxy-5-(methylsulfonylmethyl)-3-pyridinyl]-2-piperidin-1-ylthieno[3,2-d]pyrimidin-7-yl]methyl]-N-(2,2,2-trifluoroethyl)piperazine-1-carboxamide;4-[6-methoxy-5-(methylsulfonylmethyl)-3-pyridinyl]-2-piperidin-1-yl-7-[[4-(2,2,2-trifluoroethyl)piperazin-1-yl]methyl]thieno[3,2-d]pyrimidine;2,2,2-trifluoro-1-[4-[[4-[6-methoxy-5-(methylsulfonylmethyl)-3-pyridinyl]-2-piperidin-1-ylthieno[3,2-d]pyrimidin-7-yl]methyl]piperazin-1-yl]ethanone.
What is the SMILES notation for 4-[6-methoxy-5-(methylsulfonylmethyl)-3-pyridinyl]-6-methyl-7-[(4-methylsulfonylpiperazin-1-yl)methyl]-2-piperidin-1-ylthieno[3,2-d]pyrimidine;4-[[4-[6-methoxy-5-(methylsulfonylmethyl)-3-pyridinyl]-2-piperidin-1-ylthieno[3,2-d]pyrimidin-7-yl]methyl]-N-(2,2,2-trifluoroethyl)piperazine-1-carboxamide;4-[6-methoxy-5-(methylsulfonylmethyl)-3-pyridinyl]-2-piperidin-1-yl-7-[[4-(2,2,2-trifluoroethyl)piperazin-1-yl]methyl]thieno[3,2-d]pyrimidine;2,2,2-trifluoro-1-[4-[[4-[6-methoxy-5-(methylsulfonylmethyl)-3-pyridinyl]-2-piperidin-1-ylthieno[3,2-d]pyrimidin-7-yl]methyl]piperazin-1-yl]ethanone?
The canonical SMILES for 4-[6-methoxy-5-(methylsulfonylmethyl)-3-pyridinyl]-6-methyl-7-[(4-methylsulfonylpiperazin-1-yl)methyl]-2-piperidin-1-ylthieno[3,2-d]pyrimidine;4-[[4-[6-methoxy-5-(methylsulfonylmethyl)-3-pyridinyl]-2-piperidin-1-ylthieno[3,2-d]pyrimidin-7-yl]methyl]-N-(2,2,2-trifluoroethyl)piperazine-1-carboxamide;4-[6-methoxy-5-(methylsulfonylmethyl)-3-pyridinyl]-2-piperidin-1-yl-7-[[4-(2,2,2-trifluoroethyl)piperazin-1-yl]methyl]thieno[3,2-d]pyrimidine;2,2,2-trifluoro-1-[4-[[4-[6-methoxy-5-(methylsulfonylmethyl)-3-pyridinyl]-2-piperidin-1-ylthieno[3,2-d]pyrimidin-7-yl]methyl]piperazin-1-yl]ethanone is COc1ncc(-c2nc(N3CCCCC3)nc3c(CN4CCN(C(=O)C(F)(F)F)CC4)csc23)cc1CS(C)(=O)=O.COc1ncc(-c2nc(N3CCCCC3)nc3c(CN4CCN(C(=O)NCC(F)(F)F)CC4)csc23)cc1CS(C)(=O)=O.COc1ncc(-c2nc(N3CCCCC3)nc3c(CN4CCN(CC(F)(F)F)CC4)csc23)cc1CS(C)(=O)=O.COc1ncc(-c2nc(N3CCCCC3)nc3c(CN4CCN(S(C)(=O)=O)CC4)c(C)sc23)cc1CS(C)(=O)=O.
What is the InChIKey of 4-[6-methoxy-5-(methylsulfonylmethyl)-3-pyridinyl]-6-methyl-7-[(4-methylsulfonylpiperazin-1-yl)methyl]-2-piperidin-1-ylthieno[3,2-d]pyrimidine;4-[[4-[6-methoxy-5-(methylsulfonylmethyl)-3-pyridinyl]-2-piperidin-1-ylthieno[3,2-d]pyrimidin-7-yl]methyl]-N-(2,2,2-trifluoroethyl)piperazine-1-carboxamide;4-[6-methoxy-5-(methylsulfonylmethyl)-3-pyridinyl]-2-piperidin-1-yl-7-[[4-(2,2,2-trifluoroethyl)piperazin-1-yl]methyl]thieno[3,2-d]pyrimidine;2,2,2-trifluoro-1-[4-[[4-[6-methoxy-5-(methylsulfonylmethyl)-3-pyridinyl]-2-piperidin-1-ylthieno[3,2-d]pyrimidin-7-yl]methyl]piperazin-1-yl]ethanone?
The InChIKey is BEDKAEDEQWOTAD-UHFFFAOYSA-N. The full InChI is InChI=1S/C27H34F3N7O4S2.C26H31F3N6O4S2.C26H33F3N6O3S2.C26H36N6O5S3/c1-41-24-19(16-43(2,39)40)12-18(13-31-24)21-23-22(34-25(33-21)36-6-4-3-5-7-36)20(15-42-23)14-35-8-10-37(11-9-35)26(38)32-17-27(28,29)30;1-39-23-18(16-41(2,37)38)12-17(13-30-23)20-22-21(32-25(31-20)35-6-4-3-5-7-35)19(15-40-22)14-33-8-10-34(11-9-33)24(36)26(27,28)29;1-38-24-19(16-40(2,36)37)12-18(13-30-24)21-23-22(32-25(31-21)35-6-4-3-5-7-35)20(15-39-23)14-33-8-10-34(11-9-33)17-26(27,28)29;1-18-21(16-30-10-12-32(13-11-30)40(4,35)36)23-24(38-18)22(28-26(29-23)31-8-6-5-7-9-31)19-14-20(17-39(3,33)34)25(37-2)27-15-19/h12-13,15H,3-11,14,16-17H2,1-2H3,(H,32,38);12-13,15H,3-11,14,16H2,1-2H3;12-13,15H,3-11,14,16-17H2,1-2H3;14-15H,5-13,16-17H2,1-4H3.
What are the key properties of 4-[6-methoxy-5-(methylsulfonylmethyl)-3-pyridinyl]-6-methyl-7-[(4-methylsulfonylpiperazin-1-yl)methyl]-2-piperidin-1-ylthieno[3,2-d]pyrimidine;4-[[4-[6-methoxy-5-(methylsulfonylmethyl)-3-pyridinyl]-2-piperidin-1-ylthieno[3,2-d]pyrimidin-7-yl]methyl]-N-(2,2,2-trifluoroethyl)piperazine-1-carboxamide;4-[6-methoxy-5-(methylsulfonylmethyl)-3-pyridinyl]-2-piperidin-1-yl-7-[[4-(2,2,2-trifluoroethyl)piperazin-1-yl]methyl]thieno[3,2-d]pyrimidine;2,2,2-trifluoro-1-[4-[[4-[6-methoxy-5-(methylsulfonylmethyl)-3-pyridinyl]-2-piperidin-1-ylthieno[3,2-d]pyrimidin-7-yl]methyl]piperazin-1-yl]ethanone?
4-[6-methoxy-5-(methylsulfonylmethyl)-3-pyridinyl]-6-methyl-7-[(4-methylsulfonylpiperazin-1-yl)methyl]-2-piperidin-1-ylthieno[3,2-d]pyrimidine;4-[[4-[6-methoxy-5-(methylsulfonylmethyl)-3-pyridinyl]-2-piperidin-1-ylthieno[3,2-d]pyrimidin-7-yl]methyl]-N-(2,2,2-trifluoroethyl)piperazine-1-carboxamide;4-[6-methoxy-5-(methylsulfonylmethyl)-3-pyridinyl]-2-piperidin-1-yl-7-[[4-(2,2,2-trifluoroethyl)piperazin-1-yl]methyl]thieno[3,2-d]pyrimidine;2,2,2-trifluoro-1-[4-[[4-[6-methoxy-5-(methylsulfonylmethyl)-3-pyridinyl]-2-piperidin-1-ylthieno[3,2-d]pyrimidin-7-yl]methyl]piperazin-1-yl]ethanone has a molecular weight of 2461.97 g/mol, XLogP of 13.85, 31 rotatable bonds, 1 hydrogen bond donors, and 41 hydrogen bond acceptors.
Where does this data come from?
All data for 4-[6-methoxy-5-(methylsulfonylmethyl)-3-pyridinyl]-6-methyl-7-[(4-methylsulfonylpiperazin-1-yl)methyl]-2-piperidin-1-ylthieno[3,2-d]pyrimidine;4-[[4-[6-methoxy-5-(methylsulfonylmethyl)-3-pyridinyl]-2-piperidin-1-ylthieno[3,2-d]pyrimidin-7-yl]methyl]-N-(2,2,2-trifluoroethyl)piperazine-1-carboxamide;4-[6-methoxy-5-(methylsulfonylmethyl)-3-pyridinyl]-2-piperidin-1-yl-7-[[4-(2,2,2-trifluoroethyl)piperazin-1-yl]methyl]thieno[3,2-d]pyrimidine;2,2,2-trifluoro-1-[4-[[4-[6-methoxy-5-(methylsulfonylmethyl)-3-pyridinyl]-2-piperidin-1-ylthieno[3,2-d]pyrimidin-7-yl]methyl]piperazin-1-yl]ethanone is sourced from PubChem (CID 157320862), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).