6-[3-cyano-6-ethyl-5-fluoro-1-(5-fluoro-2-pyridinyl)indol-2-yl]-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-6-ethyl-5-fluoro-1-pyridin-2-ylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-6-ethyl-5-fluoro-1-pyrimidin-2-ylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;5-fluoro-1-(5-fluoro-2-pyridinyl)-6-methyl-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide;5-fluoro-6-methyl-1-(6-methyl-2-pyridinyl)-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide

C118H94F22N26O12S5 — CID 157322733

About 6-[3-cyano-6-ethyl-5-fluoro-1-(5-fluoro-2-pyridinyl)indol-2-yl]-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-6-ethyl-5-fluoro-1-pyridin-2-ylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-6-ethyl-5-fluoro-1-pyrimidin-2-ylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;5-fluoro-1-(5-fluoro-2-pyridinyl)-6-methyl-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide;5-fluoro-6-methyl-1-(6-methyl-2-pyridinyl)-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide

6-[3-cyano-6-ethyl-5-fluoro-1-(5-fluoro-2-pyridinyl)indol-2-yl]-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-6-ethyl-5-fluoro-1-pyridin-2-ylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-6-ethyl-5-fluoro-1-pyrimidin-2-ylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;5-fluoro-1-(5-fluoro-2-pyridinyl)-6-methyl-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide;5-fluoro-6-methyl-1-(6-methyl-2-pyridinyl)-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide (PubChem CID 157322733) has the molecular formula C118H94F22N26O12S5 and a molecular weight of 2646.51 g/mol. Its IUPAC name is 6-[3-cyano-6-ethyl-5-fluoro-1-(5-fluoro-2-pyridinyl)indol-2-yl]-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-6-ethyl-5-fluoro-1-pyridin-2-ylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-6-ethyl-5-fluoro-1-pyrimidin-2-ylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;5-fluoro-1-(5-fluoro-2-pyridinyl)-6-methyl-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide;5-fluoro-6-methyl-1-(6-methyl-2-pyridinyl)-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide.

Molecular Properties

• Compound Name: 6-[3-cyano-6-ethyl-5-fluoro-1-(5-fluoro-2-pyridinyl)indol-2-yl]-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-6-ethyl-5-fluoro-1-pyridin-2-ylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-6-ethyl-5-fluoro-1-pyrimidin-2-ylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;5-fluoro-1-(5-fluoro-2-pyridinyl)-6-methyl-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide;5-fluoro-6-methyl-1-(6-methyl-2-pyridinyl)-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide
• PubChem CID: 157322733
• Molecular Formula: C118H94F22N26O12S5
• Molecular Weight: 2646.51 g/mol
• Exact Mass: 2644.58
• IUPAC Name: 6-[3-cyano-6-ethyl-5-fluoro-1-(5-fluoro-2-pyridinyl)indol-2-yl]-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-6-ethyl-5-fluoro-1-pyridin-2-ylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-6-ethyl-5-fluoro-1-pyrimidin-2-ylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;5-fluoro-1-(5-fluoro-2-pyridinyl)-6-methyl-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide;5-fluoro-6-methyl-1-(6-methyl-2-pyridinyl)-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide
• SMILES: CCc1cc2c(cc1F)c(C#N)c(-c1ccc(S(=O)(=O)N[C@H](C)C(F)(F)F)cn1)n2-c1ccc(F)cn1.CCc1cc2c(cc1F)c(C#N)c(-c1ccc(S(=O)(=O)N[C@H](C)C(F)(F)F)cn1)n2-c1ccccn1.CCc1cc2c(cc1F)c(C#N)c(-c1ccc(S(=O)(=O)N[C@H](C)C(F)(F)F)cn1)n2-c1ncccn1.Cc1cc2c(cc1F)c(C(N)=O)c(-c1ccc(S(=O)(=O)N[C@@H](C)C(F)(F)F)cn1)n2-c1ccc(F)cn1.Cc1cccc(-n2c(-c3ccc(S(=O)(=O)N[C@@H](C)C(F)(F)F)cn3)c(C(N)=O)c3cc(F)c(C)cc32)n1
• InChI: InChI=1S/C24H18F5N5O2S.C24H21F4N5O3S.C24H19F4N5O2S.C23H18F5N5O3S.C23H18F4N6O2S/c1-3-14-8-21-17(9-19(14)26)18(10-30)23(34(21)22-7-4-15(25)11-32-22)20-6-5-16(12-31-20)37(35,36)33-13(2)24(27,28)29;1-12-9-19-16(10-17(12)25)21(23(29)34)22(33(19)20-6-4-5-13(2)31-20)18-8-7-15(11-30-18)37(35,36)32-14(3)24(26,27)28;1-3-15-10-21-17(11-19(15)25)18(12-29)23(33(21)22-6-4-5-9-30-22)20-8-7-16(13-31-20)36(34,35)32-14(2)24(26,27)28;1-11-7-18-15(8-16(11)25)20(22(29)34)21(33(18)19-6-3-13(24)9-31-19)17-5-4-14(10-30-17)37(35,36)32-12(2)23(26,27)28;1-3-14-9-20-16(10-18(14)24)17(11-28)21(33(20)22-29-7-4-8-30-22)19-6-5-15(12-31-19)36(34,35)32-13(2)23(25,26)27/h4-9,11-13,33H,3H2,1-2H3;4-11,14,32H,1-3H3,(H2,29,34);4-11,13-14,32H,3H2,1-2H3;3-10,12,32H,1-2H3,(H2,29,34);4-10,12-13,32H,3H2,1-2H3/t13-;2*14-;12-;13-/m10101/s1
• InChIKey: BEIZUTZAKFQBPT-PEBGKUSOSA-N
• XLogP: 22.38
• TPSA: 554.84 Ų
• H-Bond Donors: 7
• H-Bond Acceptors: 31
• Rotatable Bonds: 30
• Heavy Atoms: 183
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2646.51
LogP ≤ 5	22.38
H-Bond Donors ≤ 5	7
H-Bond Acceptors ≤ 10	31

Frequently Asked Questions

What is the IUPAC name of 6-[3-cyano-6-ethyl-5-fluoro-1-(5-fluoro-2-pyridinyl)indol-2-yl]-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-6-ethyl-5-fluoro-1-pyridin-2-ylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-6-ethyl-5-fluoro-1-pyrimidin-2-ylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;5-fluoro-1-(5-fluoro-2-pyridinyl)-6-methyl-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide;5-fluoro-6-methyl-1-(6-methyl-2-pyridinyl)-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide?

The IUPAC name of 6-[3-cyano-6-ethyl-5-fluoro-1-(5-fluoro-2-pyridinyl)indol-2-yl]-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-6-ethyl-5-fluoro-1-pyridin-2-ylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-6-ethyl-5-fluoro-1-pyrimidin-2-ylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;5-fluoro-1-(5-fluoro-2-pyridinyl)-6-methyl-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide;5-fluoro-6-methyl-1-(6-methyl-2-pyridinyl)-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide (CID 157322733) is 6-[3-cyano-6-ethyl-5-fluoro-1-(5-fluoro-2-pyridinyl)indol-2-yl]-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-6-ethyl-5-fluoro-1-pyridin-2-ylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-6-ethyl-5-fluoro-1-pyrimidin-2-ylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;5-fluoro-1-(5-fluoro-2-pyridinyl)-6-methyl-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide;5-fluoro-6-methyl-1-(6-methyl-2-pyridinyl)-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide.

What is the SMILES notation for 6-[3-cyano-6-ethyl-5-fluoro-1-(5-fluoro-2-pyridinyl)indol-2-yl]-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-6-ethyl-5-fluoro-1-pyridin-2-ylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-6-ethyl-5-fluoro-1-pyrimidin-2-ylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;5-fluoro-1-(5-fluoro-2-pyridinyl)-6-methyl-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide;5-fluoro-6-methyl-1-(6-methyl-2-pyridinyl)-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide?

The canonical SMILES for 6-[3-cyano-6-ethyl-5-fluoro-1-(5-fluoro-2-pyridinyl)indol-2-yl]-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-6-ethyl-5-fluoro-1-pyridin-2-ylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-6-ethyl-5-fluoro-1-pyrimidin-2-ylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;5-fluoro-1-(5-fluoro-2-pyridinyl)-6-methyl-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide;5-fluoro-6-methyl-1-(6-methyl-2-pyridinyl)-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide is CCc1cc2c(cc1F)c(C#N)c(-c1ccc(S(=O)(=O)N[C@H](C)C(F)(F)F)cn1)n2-c1ccc(F)cn1.CCc1cc2c(cc1F)c(C#N)c(-c1ccc(S(=O)(=O)N[C@H](C)C(F)(F)F)cn1)n2-c1ccccn1.CCc1cc2c(cc1F)c(C#N)c(-c1ccc(S(=O)(=O)N[C@H](C)C(F)(F)F)cn1)n2-c1ncccn1.Cc1cc2c(cc1F)c(C(N)=O)c(-c1ccc(S(=O)(=O)N[C@@H](C)C(F)(F)F)cn1)n2-c1ccc(F)cn1.Cc1cccc(-n2c(-c3ccc(S(=O)(=O)N[C@@H](C)C(F)(F)F)cn3)c(C(N)=O)c3cc(F)c(C)cc32)n1.

What is the InChIKey of 6-[3-cyano-6-ethyl-5-fluoro-1-(5-fluoro-2-pyridinyl)indol-2-yl]-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-6-ethyl-5-fluoro-1-pyridin-2-ylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-6-ethyl-5-fluoro-1-pyrimidin-2-ylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;5-fluoro-1-(5-fluoro-2-pyridinyl)-6-methyl-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide;5-fluoro-6-methyl-1-(6-methyl-2-pyridinyl)-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide?

The InChIKey is BEIZUTZAKFQBPT-PEBGKUSOSA-N. The full InChI is InChI=1S/C24H18F5N5O2S.C24H21F4N5O3S.C24H19F4N5O2S.C23H18F5N5O3S.C23H18F4N6O2S/c1-3-14-8-21-17(9-19(14)26)18(10-30)23(34(21)22-7-4-15(25)11-32-22)20-6-5-16(12-31-20)37(35,36)33-13(2)24(27,28)29;1-12-9-19-16(10-17(12)25)21(23(29)34)22(33(19)20-6-4-5-13(2)31-20)18-8-7-15(11-30-18)37(35,36)32-14(3)24(26,27)28;1-3-15-10-21-17(11-19(15)25)18(12-29)23(33(21)22-6-4-5-9-30-22)20-8-7-16(13-31-20)36(34,35)32-14(2)24(26,27)28;1-11-7-18-15(8-16(11)25)20(22(29)34)21(33(18)19-6-3-13(24)9-31-19)17-5-4-14(10-30-17)37(35,36)32-12(2)23(26,27)28;1-3-14-9-20-16(10-18(14)24)17(11-28)21(33(20)22-29-7-4-8-30-22)19-6-5-15(12-31-19)36(34,35)32-13(2)23(25,26)27/h4-9,11-13,33H,3H2,1-2H3;4-11,14,32H,1-3H3,(H2,29,34);4-11,13-14,32H,3H2,1-2H3;3-10,12,32H,1-2H3,(H2,29,34);4-10,12-13,32H,3H2,1-2H3/t13-;2*14-;12-;13-/m10101/s1.

What are the key properties of 6-[3-cyano-6-ethyl-5-fluoro-1-(5-fluoro-2-pyridinyl)indol-2-yl]-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-6-ethyl-5-fluoro-1-pyridin-2-ylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-6-ethyl-5-fluoro-1-pyrimidin-2-ylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;5-fluoro-1-(5-fluoro-2-pyridinyl)-6-methyl-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide;5-fluoro-6-methyl-1-(6-methyl-2-pyridinyl)-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide?

6-[3-cyano-6-ethyl-5-fluoro-1-(5-fluoro-2-pyridinyl)indol-2-yl]-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-6-ethyl-5-fluoro-1-pyridin-2-ylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-6-ethyl-5-fluoro-1-pyrimidin-2-ylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;5-fluoro-1-(5-fluoro-2-pyridinyl)-6-methyl-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide;5-fluoro-6-methyl-1-(6-methyl-2-pyridinyl)-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide has a molecular weight of 2646.51 g/mol, XLogP of 22.38, 30 rotatable bonds, 7 hydrogen bond donors, and 31 hydrogen bond acceptors.

Where does this data come from?

All data for 6-[3-cyano-6-ethyl-5-fluoro-1-(5-fluoro-2-pyridinyl)indol-2-yl]-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-6-ethyl-5-fluoro-1-pyridin-2-ylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-6-ethyl-5-fluoro-1-pyrimidin-2-ylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;5-fluoro-1-(5-fluoro-2-pyridinyl)-6-methyl-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide;5-fluoro-6-methyl-1-(6-methyl-2-pyridinyl)-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide is sourced from PubChem (CID 157322733), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).