N-(6-bromo-1-cyclobutyl-4-fluorobenzimidazol-2-yl)-3,3-dimethylbutanamide;N-(1-tert-butyl-6-cyano-4-fluorobenzimidazol-2-yl)-3-(2-fluorophenyl)-3-hydroxybutanamide;N-(1-tert-butyl-4,7-difluoro-6-isocyanobenzimidazol-2-yl)-3,3-dimethylbutanamide;N-(5-chloro-6-cyano-1-cyclobutylbenzimidazol-2-yl)-3-hydroxy-3-phenylbutanamide;N-(6-cyano-1-cyclobutyl-7-fluorobenzimidazol-2-yl)-5,5-difluoro-3,3-dimethylhexanamide;N-(6-cyano-1-cyclobutyl-5-fluorobenzimidazol-2-yl)-3-hydroxy-3-phenylbutanamide;N-[6-cyano-1-(cyclopropylmethyl)benzimidazol-2-yl]-3-hydroxy-3-phenylbutanamide;N-[1-cyclobutyl-4-fluoro-6-(1-hydroxycyclobutyl)benzimidazol-2-yl]-3,3-dimethylbutanamide;N-[1-cyclobutyl-4-fluoro-6-(2-hydroxypropan-2-yl)benzimidazol-2-yl]-4,4-dideuterio-3,3-bis(trideuteriomethyl)pentanamide;N-[1-cyclobutyl-6-(2-hydroxypropan-2-yl)benzimidazol-2-yl]-2-(2,3,3-trifluoro-2-methylcyclobutyl)acetamide;N-[6-(difluoromethoxy)-7-fluoro-1-(1-methylcyclobutyl)benzimidazol-2-yl]-3,3-dimethylbutanamide;N-[6-(difluoromethoxy)-1-(1-methylcyclobutyl)benzimidazol-2-yl]-3,3-dimethylbutanamide

C244H285BrClF19N42O21 — CID 157326182

IUPACN-(6-bromo-1-cyclobutyl-4-fluorobenzimidazol-2-yl)-3,3-dimethylbutanamide;N-(1-tert-butyl-6-cyano-4-fluorobenzimidazol-2-yl)-3-(2-fluorophenyl)-3-hydroxybutanamide;N-(1-tert-butyl-4,7-difluoro-6-isocyanobenzimidazol-2-yl)-3,3-dimethylbutanamide;N-(5-chloro-6-cyano-1-cyclobutylbenzimidazol-2-yl)-3-hydroxy-3-phenylbutanamide;N-(6-cyano-1-cyclobutyl-7-fluorobenzimidazol-2-yl)-5,5-difluoro-3,3-dimethylhexanamide;N-(6-cyano-1-cyclobutyl-5-fluorobenzimidazol-2-yl)-3-hydroxy-3-phenylbutanamide;N-[6-cyano-1-(cyclopropylmethyl)benzimidazol-2-yl]-3-hydroxy-3-phenylbutanamide;N-[1-cyclobutyl-4-fluoro-6-(1-hydroxycyclobutyl)benzimidazol-2-yl]-3,3-dimethylbutanamide;N-[1-cyclobutyl-4-fluoro-6-(2-hydroxypropan-2-yl)benzimidazol-2-yl]-4,4-dideuterio-3,3-bis(trideuteriomethyl)pentanamide;N-[1-cyclobutyl-6-(2-hydroxypropan-2-yl)benzimidazol-2-yl]-2-(2,3,3-trifluoro-2-methylcyclobutyl)acetamide;N-[6-(difluoromethoxy)-7-fluoro-1-(1-methylcyclobutyl)benzimidazol-2-yl]-3,3-dimethylbutanamide;N-[6-(difluoromethoxy)-1-(1-methylcyclobutyl)benzimidazol-2-yl]-3,3-dimethylbutanamide
SMILESCC(C)(C)CC(=O)Nc1nc2c(F)cc(Br)cc2n1C1CCC1.CC(C)(C)CC(=O)Nc1nc2c(F)cc(C3(O)CCC3)cc2n1C1CCC1.CC(C)(C)CC(=O)Nc1nc2ccc(OC(F)F)c(F)c2n1C1(C)CCC1.CC(C)(C)CC(=O)Nc1nc2ccc(OC(F)F)cc2n1C1(C)CCC1.CC(C)(O)c1ccc2nc(NC(=O)CC3CC(F)(F)C3(C)F)n(C3CCC3)c2c1.CC(F)(F)CC(C)(C)CC(=O)Nc1nc2ccc(C#N)c(F)c2n1C1CCC1.CC(O)(CC(=O)Nc1nc2c(F)cc(C#N)cc2n1C(C)(C)C)c1ccccc1F.CC(O)(CC(=O)Nc1nc2cc(Cl)c(C#N)cc2n1C1CCC1)c1ccccc1.CC(O)(CC(=O)Nc1nc2cc(F)c(C#N)cc2n1C1CCC1)c1ccccc1.CC(O)(CC(=O)Nc1nc2ccc(C#N)cc2n1CC1CC1)c1ccccc1.[2H]C([2H])([2H])C(CC(=O)Nc1nc2c(F)cc(C(C)(C)O)cc2n1C1CCC1)(C([2H])([2H])[2H])C([2H])([2H])C.[C-]#[N+]c1cc(F)c2nc(NC(=O)CC(C)(C)C)n(C(C)(C)C)c2c1F
InChIInChI=1S/C22H21ClN4O2.C22H22F2N4O2.C22H21FN4O2.C22H22N4O2.C21H26F3N3O2.C21H28FN3O2.C21H30FN3O2.C20H23F3N4O.C19H24F3N3O2.C19H25F2N3O2.C18H22F2N4O.C17H21BrFN3O/c1-22(29,15-6-3-2-4-7-15)12-20(28)26-21-25-18-11-17(23)14(13-24)10-19(18)27(21)16-8-5-9-16;1-21(2,3)28-17-10-13(12-25)9-16(24)19(17)27-20(28)26-18(29)11-22(4,30)14-7-5-6-8-15(14)23;1-22(29,15-6-3-2-4-7-15)12-20(28)26-21-25-18-11-17(23)14(13-24)10-19(18)27(21)16-8-5-9-16;1-22(28,17-5-3-2-4-6-17)12-20(27)25-21-24-18-10-9-16(13-23)11-19(18)26(21)14-15-7-8-15;1-19(2,29)12-7-8-15-16(9-12)27(14-5-4-6-14)18(25-15)26-17(28)10-13-11-21(23,24)20(13,3)22;1-20(2,3)12-17(26)23-19-24-18-15(22)10-13(21(27)8-5-9-21)11-16(18)25(19)14-6-4-7-14;1-6-20(2,3)12-17(26)23-19-24-18-15(22)10-13(21(4,5)27)11-16(18)25(19)14-8-7-9-14;1-19(2,11-20(3,22)23)9-15(28)26-18-25-14-8-7-12(10-24)16(21)17(14)27(18)13-5-4-6-13;1-18(2,3)10-13(26)24-17-23-11-6-7-12(27-16(21)22)14(20)15(11)25(17)19(4)8-5-9-19;1-18(2,3)11-15(25)23-17-22-13-7-6-12(26-16(20)21)10-14(13)24(17)19(4)8-5-9-19;1-17(2,3)9-12(25)22-16-23-14-10(19)8-11(21-7)13(20)15(14)24(16)18(4,5)6;1-17(2,3)9-14(23)20-16-21-15-12(19)7-10(18)8-13(15)22(16)11-5-4-6-11/h2-4,6-7,10-11,16,29H,5,8-9,12H2,1H3,(H,25,26,28);5-10,30H,11H2,1-4H3,(H,26,27,29);2-4,6-7,10-11,16,29H,5,8-9,12H2,1H3,(H,25,26,28);2-6,9-11,15,28H,7-8,12,14H2,1H3,(H,24,25,27);7-9,13-14,29H,4-6,10-11H2,1-3H3,(H,25,26,28);10-11,14,27H,4-9,12H2,1-3H3,(H,23,24,26);10-11,14,27H,6-9,12H2,1-5H3,(H,23,24,26);7-8,13H,4-6,9,11H2,1-3H3,(H,25,26,28);6-7,16H,5,8-10H2,1-4H3,(H,23,24,26);6-7,10,16H,5,8-9,11H2,1-4H3,(H,22,23,25);8H,9H2,1-6H3,(H,22,23,25);7-8,11H,4-6,9H2,1-3H3,(H,20,21,23)/i;;;;;;2D3,3D3,6D2;;;;;
InChIKeyBETBEUWDADQVIK-HPIXPNRJSA-N
MW4626.60 g/mol
LogP55.67
Rot. Bonds58

About N-(6-bromo-1-cyclobutyl-4-fluorobenzimidazol-2-yl)-3,3-dimethylbutanamide;N-(1-tert-butyl-6-cyano-4-fluorobenzimidazol-2-yl)-3-(2-fluorophenyl)-3-hydroxybutanamide;N-(1-tert-butyl-4,7-difluoro-6-isocyanobenzimidazol-2-yl)-3,3-dimethylbutanamide;N-(5-chloro-6-cyano-1-cyclobutylbenzimidazol-2-yl)-3-hydroxy-3-phenylbutanamide;N-(6-cyano-1-cyclobutyl-7-fluorobenzimidazol-2-yl)-5,5-difluoro-3,3-dimethylhexanamide;N-(6-cyano-1-cyclobutyl-5-fluorobenzimidazol-2-yl)-3-hydroxy-3-phenylbutanamide;N-[6-cyano-1-(cyclopropylmethyl)benzimidazol-2-yl]-3-hydroxy-3-phenylbutanamide;N-[1-cyclobutyl-4-fluoro-6-(1-hydroxycyclobutyl)benzimidazol-2-yl]-3,3-dimethylbutanamide;N-[1-cyclobutyl-4-fluoro-6-(2-hydroxypropan-2-yl)benzimidazol-2-yl]-4,4-dideuterio-3,3-bis(trideuteriomethyl)pentanamide;N-[1-cyclobutyl-6-(2-hydroxypropan-2-yl)benzimidazol-2-yl]-2-(2,3,3-trifluoro-2-methylcyclobutyl)acetamide;N-[6-(difluoromethoxy)-7-fluoro-1-(1-methylcyclobutyl)benzimidazol-2-yl]-3,3-dimethylbutanamide;N-[6-(difluoromethoxy)-1-(1-methylcyclobutyl)benzimidazol-2-yl]-3,3-dimethylbutanamide

N-(6-bromo-1-cyclobutyl-4-fluorobenzimidazol-2-yl)-3,3-dimethylbutanamide;N-(1-tert-butyl-6-cyano-4-fluorobenzimidazol-2-yl)-3-(2-fluorophenyl)-3-hydroxybutanamide;N-(1-tert-butyl-4,7-difluoro-6-isocyanobenzimidazol-2-yl)-3,3-dimethylbutanamide;N-(5-chloro-6-cyano-1-cyclobutylbenzimidazol-2-yl)-3-hydroxy-3-phenylbutanamide;N-(6-cyano-1-cyclobutyl-7-fluorobenzimidazol-2-yl)-5,5-difluoro-3,3-dimethylhexanamide;N-(6-cyano-1-cyclobutyl-5-fluorobenzimidazol-2-yl)-3-hydroxy-3-phenylbutanamide;N-[6-cyano-1-(cyclopropylmethyl)benzimidazol-2-yl]-3-hydroxy-3-phenylbutanamide;N-[1-cyclobutyl-4-fluoro-6-(1-hydroxycyclobutyl)benzimidazol-2-yl]-3,3-dimethylbutanamide;N-[1-cyclobutyl-4-fluoro-6-(2-hydroxypropan-2-yl)benzimidazol-2-yl]-4,4-dideuterio-3,3-bis(trideuteriomethyl)pentanamide;N-[1-cyclobutyl-6-(2-hydroxypropan-2-yl)benzimidazol-2-yl]-2-(2,3,3-trifluoro-2-methylcyclobutyl)acetamide;N-[6-(difluoromethoxy)-7-fluoro-1-(1-methylcyclobutyl)benzimidazol-2-yl]-3,3-dimethylbutanamide;N-[6-(difluoromethoxy)-1-(1-methylcyclobutyl)benzimidazol-2-yl]-3,3-dimethylbutanamide (PubChem CID 157326182) has the molecular formula C244H285BrClF19N42O21 and a molecular weight of 4626.60 g/mol. Its IUPAC name is N-(6-bromo-1-cyclobutyl-4-fluorobenzimidazol-2-yl)-3,3-dimethylbutanamide;N-(1-tert-butyl-6-cyano-4-fluorobenzimidazol-2-yl)-3-(2-fluorophenyl)-3-hydroxybutanamide;N-(1-tert-butyl-4,7-difluoro-6-isocyanobenzimidazol-2-yl)-3,3-dimethylbutanamide;N-(5-chloro-6-cyano-1-cyclobutylbenzimidazol-2-yl)-3-hydroxy-3-phenylbutanamide;N-(6-cyano-1-cyclobutyl-7-fluorobenzimidazol-2-yl)-5,5-difluoro-3,3-dimethylhexanamide;N-(6-cyano-1-cyclobutyl-5-fluorobenzimidazol-2-yl)-3-hydroxy-3-phenylbutanamide;N-[6-cyano-1-(cyclopropylmethyl)benzimidazol-2-yl]-3-hydroxy-3-phenylbutanamide;N-[1-cyclobutyl-4-fluoro-6-(1-hydroxycyclobutyl)benzimidazol-2-yl]-3,3-dimethylbutanamide;N-[1-cyclobutyl-4-fluoro-6-(2-hydroxypropan-2-yl)benzimidazol-2-yl]-4,4-dideuterio-3,3-bis(trideuteriomethyl)pentanamide;N-[1-cyclobutyl-6-(2-hydroxypropan-2-yl)benzimidazol-2-yl]-2-(2,3,3-trifluoro-2-methylcyclobutyl)acetamide;N-[6-(difluoromethoxy)-7-fluoro-1-(1-methylcyclobutyl)benzimidazol-2-yl]-3,3-dimethylbutanamide;N-[6-(difluoromethoxy)-1-(1-methylcyclobutyl)benzimidazol-2-yl]-3,3-dimethylbutanamide.

Molecular Properties

Compound NameN-(6-bromo-1-cyclobutyl-4-fluorobenzimidazol-2-yl)-3,3-dimethylbutanamide;N-(1-tert-butyl-6-cyano-4-fluorobenzimidazol-2-yl)-3-(2-fluorophenyl)-3-hydroxybutanamide;N-(1-tert-butyl-4,7-difluoro-6-isocyanobenzimidazol-2-yl)-3,3-dimethylbutanamide;N-(5-chloro-6-cyano-1-cyclobutylbenzimidazol-2-yl)-3-hydroxy-3-phenylbutanamide;N-(6-cyano-1-cyclobutyl-7-fluorobenzimidazol-2-yl)-5,5-difluoro-3,3-dimethylhexanamide;N-(6-cyano-1-cyclobutyl-5-fluorobenzimidazol-2-yl)-3-hydroxy-3-phenylbutanamide;N-[6-cyano-1-(cyclopropylmethyl)benzimidazol-2-yl]-3-hydroxy-3-phenylbutanamide;N-[1-cyclobutyl-4-fluoro-6-(1-hydroxycyclobutyl)benzimidazol-2-yl]-3,3-dimethylbutanamide;N-[1-cyclobutyl-4-fluoro-6-(2-hydroxypropan-2-yl)benzimidazol-2-yl]-4,4-dideuterio-3,3-bis(trideuteriomethyl)pentanamide;N-[1-cyclobutyl-6-(2-hydroxypropan-2-yl)benzimidazol-2-yl]-2-(2,3,3-trifluoro-2-methylcyclobutyl)acetamide;N-[6-(difluoromethoxy)-7-fluoro-1-(1-methylcyclobutyl)benzimidazol-2-yl]-3,3-dimethylbutanamide;N-[6-(difluoromethoxy)-1-(1-methylcyclobutyl)benzimidazol-2-yl]-3,3-dimethylbutanamide
PubChem CID157326182
Molecular FormulaC244H285BrClF19N42O21
Molecular Weight4626.60 g/mol
Exact Mass4622.16
IUPAC NameN-(6-bromo-1-cyclobutyl-4-fluorobenzimidazol-2-yl)-3,3-dimethylbutanamide;N-(1-tert-butyl-6-cyano-4-fluorobenzimidazol-2-yl)-3-(2-fluorophenyl)-3-hydroxybutanamide;N-(1-tert-butyl-4,7-difluoro-6-isocyanobenzimidazol-2-yl)-3,3-dimethylbutanamide;N-(5-chloro-6-cyano-1-cyclobutylbenzimidazol-2-yl)-3-hydroxy-3-phenylbutanamide;N-(6-cyano-1-cyclobutyl-7-fluorobenzimidazol-2-yl)-5,5-difluoro-3,3-dimethylhexanamide;N-(6-cyano-1-cyclobutyl-5-fluorobenzimidazol-2-yl)-3-hydroxy-3-phenylbutanamide;N-[6-cyano-1-(cyclopropylmethyl)benzimidazol-2-yl]-3-hydroxy-3-phenylbutanamide;N-[1-cyclobutyl-4-fluoro-6-(1-hydroxycyclobutyl)benzimidazol-2-yl]-3,3-dimethylbutanamide;N-[1-cyclobutyl-4-fluoro-6-(2-hydroxypropan-2-yl)benzimidazol-2-yl]-4,4-dideuterio-3,3-bis(trideuteriomethyl)pentanamide;N-[1-cyclobutyl-6-(2-hydroxypropan-2-yl)benzimidazol-2-yl]-2-(2,3,3-trifluoro-2-methylcyclobutyl)acetamide;N-[6-(difluoromethoxy)-7-fluoro-1-(1-methylcyclobutyl)benzimidazol-2-yl]-3,3-dimethylbutanamide;N-[6-(difluoromethoxy)-1-(1-methylcyclobutyl)benzimidazol-2-yl]-3,3-dimethylbutanamide
SMILESCC(C)(C)CC(=O)Nc1nc2c(F)cc(Br)cc2n1C1CCC1.CC(C)(C)CC(=O)Nc1nc2c(F)cc(C3(O)CCC3)cc2n1C1CCC1.CC(C)(C)CC(=O)Nc1nc2ccc(OC(F)F)c(F)c2n1C1(C)CCC1.CC(C)(C)CC(=O)Nc1nc2ccc(OC(F)F)cc2n1C1(C)CCC1.CC(C)(O)c1ccc2nc(NC(=O)CC3CC(F)(F)C3(C)F)n(C3CCC3)c2c1.CC(F)(F)CC(C)(C)CC(=O)Nc1nc2ccc(C#N)c(F)c2n1C1CCC1.CC(O)(CC(=O)Nc1nc2c(F)cc(C#N)cc2n1C(C)(C)C)c1ccccc1F.CC(O)(CC(=O)Nc1nc2cc(Cl)c(C#N)cc2n1C1CCC1)c1ccccc1.CC(O)(CC(=O)Nc1nc2cc(F)c(C#N)cc2n1C1CCC1)c1ccccc1.CC(O)(CC(=O)Nc1nc2ccc(C#N)cc2n1CC1CC1)c1ccccc1.[2H]C([2H])([2H])C(CC(=O)Nc1nc2c(F)cc(C(C)(C)O)cc2n1C1CCC1)(C([2H])([2H])[2H])C([2H])([2H])C.[C-]#[N+]c1cc(F)c2nc(NC(=O)CC(C)(C)C)n(C(C)(C)C)c2c1F
InChIInChI=1S/C22H21ClN4O2.C22H22F2N4O2.C22H21FN4O2.C22H22N4O2.C21H26F3N3O2.C21H28FN3O2.C21H30FN3O2.C20H23F3N4O.C19H24F3N3O2.C19H25F2N3O2.C18H22F2N4O.C17H21BrFN3O/c1-22(29,15-6-3-2-4-7-15)12-20(28)26-21-25-18-11-17(23)14(13-24)10-19(18)27(21)16-8-5-9-16;1-21(2,3)28-17-10-13(12-25)9-16(24)19(17)27-20(28)26-18(29)11-22(4,30)14-7-5-6-8-15(14)23;1-22(29,15-6-3-2-4-7-15)12-20(28)26-21-25-18-11-17(23)14(13-24)10-19(18)27(21)16-8-5-9-16;1-22(28,17-5-3-2-4-6-17)12-20(27)25-21-24-18-10-9-16(13-23)11-19(18)26(21)14-15-7-8-15;1-19(2,29)12-7-8-15-16(9-12)27(14-5-4-6-14)18(25-15)26-17(28)10-13-11-21(23,24)20(13,3)22;1-20(2,3)12-17(26)23-19-24-18-15(22)10-13(21(27)8-5-9-21)11-16(18)25(19)14-6-4-7-14;1-6-20(2,3)12-17(26)23-19-24-18-15(22)10-13(21(4,5)27)11-16(18)25(19)14-8-7-9-14;1-19(2,11-20(3,22)23)9-15(28)26-18-25-14-8-7-12(10-24)16(21)17(14)27(18)13-5-4-6-13;1-18(2,3)10-13(26)24-17-23-11-6-7-12(27-16(21)22)14(20)15(11)25(17)19(4)8-5-9-19;1-18(2,3)11-15(25)23-17-22-13-7-6-12(26-16(20)21)10-14(13)24(17)19(4)8-5-9-19;1-17(2,3)9-12(25)22-16-23-14-10(19)8-11(21-7)13(20)15(14)24(16)18(4,5)6;1-17(2,3)9-14(23)20-16-21-15-12(19)7-10(18)8-13(15)22(16)11-5-4-6-11/h2-4,6-7,10-11,16,29H,5,8-9,12H2,1H3,(H,25,26,28);5-10,30H,11H2,1-4H3,(H,26,27,29);2-4,6-7,10-11,16,29H,5,8-9,12H2,1H3,(H,25,26,28);2-6,9-11,15,28H,7-8,12,14H2,1H3,(H,24,25,27);7-9,13-14,29H,4-6,10-11H2,1-3H3,(H,25,26,28);10-11,14,27H,4-9,12H2,1-3H3,(H,23,24,26);10-11,14,27H,6-9,12H2,1-5H3,(H,23,24,26);7-8,13H,4-6,9,11H2,1-3H3,(H,25,26,28);6-7,16H,5,8-10H2,1-4H3,(H,23,24,26);6-7,10,16H,5,8-9,11H2,1-4H3,(H,22,23,25);8H,9H2,1-6H3,(H,22,23,25);7-8,11H,4-6,9H2,1-3H3,(H,20,21,23)/i;;;;;;2D3,3D3,6D2;;;;;
InChIKeyBETBEUWDADQVIK-HPIXPNRJSA-N
XLogP55.67
TPSA846.42 Ų
H-Bond Donors19
H-Bond Acceptors50
Rotatable Bonds58
Heavy Atoms328
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5004626.60
LogP ≤ 555.67
H-Bond Donors ≤ 519
H-Bond Acceptors ≤ 1050

Analyze N-(6-bromo-1-cyclobutyl-4-fluorobenzimidazol-2-yl)-3,3-dimethylbutanamide;N-(1-tert-butyl-6-cyano-4-fluorobenzimidazol-2-yl)-3-(2-fluorophenyl)-3-hydroxybutanamide;N-(1-tert-butyl-4,7-difluoro-6-isocyanobenzimidazol-2-yl)-3,3-dimethylbutanamide;N-(5-chloro-6-cyano-1-cyclobutylbenzimidazol-2-yl)-3-hydroxy-3-phenylbutanamide;N-(6-cyano-1-cyclobutyl-7-fluorobenzimidazol-2-yl)-5,5-difluoro-3,3-dimethylhexanamide;N-(6-cyano-1-cyclobutyl-5-fluorobenzimidazol-2-yl)-3-hydroxy-3-phenylbutanamide;N-[6-cyano-1-(cyclopropylmethyl)benzimidazol-2-yl]-3-hydroxy-3-phenylbutanamide;N-[1-cyclobutyl-4-fluoro-6-(1-hydroxycyclobutyl)benzimidazol-2-yl]-3,3-dimethylbutanamide;N-[1-cyclobutyl-4-fluoro-6-(2-hydroxypropan-2-yl)benzimidazol-2-yl]-4,4-dideuterio-3,3-bis(trideuteriomethyl)pentanamide;N-[1-cyclobutyl-6-(2-hydroxypropan-2-yl)benzimidazol-2-yl]-2-(2,3,3-trifluoro-2-methylcyclobutyl)acetamide;N-[6-(difluoromethoxy)-7-fluoro-1-(1-methylcyclobutyl)benzimidazol-2-yl]-3,3-dimethylbutanamide;N-[6-(difluoromethoxy)-1-(1-methylcyclobutyl)benzimidazol-2-yl]-3,3-dimethylbutanamide with MolForge

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What is the IUPAC name of N-(6-bromo-1-cyclobutyl-4-fluorobenzimidazol-2-yl)-3,3-dimethylbutanamide;N-(1-tert-butyl-6-cyano-4-fluorobenzimidazol-2-yl)-3-(2-fluorophenyl)-3-hydroxybutanamide;N-(1-tert-butyl-4,7-difluoro-6-isocyanobenzimidazol-2-yl)-3,3-dimethylbutanamide;N-(5-chloro-6-cyano-1-cyclobutylbenzimidazol-2-yl)-3-hydroxy-3-phenylbutanamide;N-(6-cyano-1-cyclobutyl-7-fluorobenzimidazol-2-yl)-5,5-difluoro-3,3-dimethylhexanamide;N-(6-cyano-1-cyclobutyl-5-fluorobenzimidazol-2-yl)-3-hydroxy-3-phenylbutanamide;N-[6-cyano-1-(cyclopropylmethyl)benzimidazol-2-yl]-3-hydroxy-3-phenylbutanamide;N-[1-cyclobutyl-4-fluoro-6-(1-hydroxycyclobutyl)benzimidazol-2-yl]-3,3-dimethylbutanamide;N-[1-cyclobutyl-4-fluoro-6-(2-hydroxypropan-2-yl)benzimidazol-2-yl]-4,4-dideuterio-3,3-bis(trideuteriomethyl)pentanamide;N-[1-cyclobutyl-6-(2-hydroxypropan-2-yl)benzimidazol-2-yl]-2-(2,3,3-trifluoro-2-methylcyclobutyl)acetamide;N-[6-(difluoromethoxy)-7-fluoro-1-(1-methylcyclobutyl)benzimidazol-2-yl]-3,3-dimethylbutanamide;N-[6-(difluoromethoxy)-1-(1-methylcyclobutyl)benzimidazol-2-yl]-3,3-dimethylbutanamide?
The IUPAC name of N-(6-bromo-1-cyclobutyl-4-fluorobenzimidazol-2-yl)-3,3-dimethylbutanamide;N-(1-tert-butyl-6-cyano-4-fluorobenzimidazol-2-yl)-3-(2-fluorophenyl)-3-hydroxybutanamide;N-(1-tert-butyl-4,7-difluoro-6-isocyanobenzimidazol-2-yl)-3,3-dimethylbutanamide;N-(5-chloro-6-cyano-1-cyclobutylbenzimidazol-2-yl)-3-hydroxy-3-phenylbutanamide;N-(6-cyano-1-cyclobutyl-7-fluorobenzimidazol-2-yl)-5,5-difluoro-3,3-dimethylhexanamide;N-(6-cyano-1-cyclobutyl-5-fluorobenzimidazol-2-yl)-3-hydroxy-3-phenylbutanamide;N-[6-cyano-1-(cyclopropylmethyl)benzimidazol-2-yl]-3-hydroxy-3-phenylbutanamide;N-[1-cyclobutyl-4-fluoro-6-(1-hydroxycyclobutyl)benzimidazol-2-yl]-3,3-dimethylbutanamide;N-[1-cyclobutyl-4-fluoro-6-(2-hydroxypropan-2-yl)benzimidazol-2-yl]-4,4-dideuterio-3,3-bis(trideuteriomethyl)pentanamide;N-[1-cyclobutyl-6-(2-hydroxypropan-2-yl)benzimidazol-2-yl]-2-(2,3,3-trifluoro-2-methylcyclobutyl)acetamide;N-[6-(difluoromethoxy)-7-fluoro-1-(1-methylcyclobutyl)benzimidazol-2-yl]-3,3-dimethylbutanamide;N-[6-(difluoromethoxy)-1-(1-methylcyclobutyl)benzimidazol-2-yl]-3,3-dimethylbutanamide (CID 157326182) is N-(6-bromo-1-cyclobutyl-4-fluorobenzimidazol-2-yl)-3,3-dimethylbutanamide;N-(1-tert-butyl-6-cyano-4-fluorobenzimidazol-2-yl)-3-(2-fluorophenyl)-3-hydroxybutanamide;N-(1-tert-butyl-4,7-difluoro-6-isocyanobenzimidazol-2-yl)-3,3-dimethylbutanamide;N-(5-chloro-6-cyano-1-cyclobutylbenzimidazol-2-yl)-3-hydroxy-3-phenylbutanamide;N-(6-cyano-1-cyclobutyl-7-fluorobenzimidazol-2-yl)-5,5-difluoro-3,3-dimethylhexanamide;N-(6-cyano-1-cyclobutyl-5-fluorobenzimidazol-2-yl)-3-hydroxy-3-phenylbutanamide;N-[6-cyano-1-(cyclopropylmethyl)benzimidazol-2-yl]-3-hydroxy-3-phenylbutanamide;N-[1-cyclobutyl-4-fluoro-6-(1-hydroxycyclobutyl)benzimidazol-2-yl]-3,3-dimethylbutanamide;N-[1-cyclobutyl-4-fluoro-6-(2-hydroxypropan-2-yl)benzimidazol-2-yl]-4,4-dideuterio-3,3-bis(trideuteriomethyl)pentanamide;N-[1-cyclobutyl-6-(2-hydroxypropan-2-yl)benzimidazol-2-yl]-2-(2,3,3-trifluoro-2-methylcyclobutyl)acetamide;N-[6-(difluoromethoxy)-7-fluoro-1-(1-methylcyclobutyl)benzimidazol-2-yl]-3,3-dimethylbutanamide;N-[6-(difluoromethoxy)-1-(1-methylcyclobutyl)benzimidazol-2-yl]-3,3-dimethylbutanamide.
What is the SMILES notation for N-(6-bromo-1-cyclobutyl-4-fluorobenzimidazol-2-yl)-3,3-dimethylbutanamide;N-(1-tert-butyl-6-cyano-4-fluorobenzimidazol-2-yl)-3-(2-fluorophenyl)-3-hydroxybutanamide;N-(1-tert-butyl-4,7-difluoro-6-isocyanobenzimidazol-2-yl)-3,3-dimethylbutanamide;N-(5-chloro-6-cyano-1-cyclobutylbenzimidazol-2-yl)-3-hydroxy-3-phenylbutanamide;N-(6-cyano-1-cyclobutyl-7-fluorobenzimidazol-2-yl)-5,5-difluoro-3,3-dimethylhexanamide;N-(6-cyano-1-cyclobutyl-5-fluorobenzimidazol-2-yl)-3-hydroxy-3-phenylbutanamide;N-[6-cyano-1-(cyclopropylmethyl)benzimidazol-2-yl]-3-hydroxy-3-phenylbutanamide;N-[1-cyclobutyl-4-fluoro-6-(1-hydroxycyclobutyl)benzimidazol-2-yl]-3,3-dimethylbutanamide;N-[1-cyclobutyl-4-fluoro-6-(2-hydroxypropan-2-yl)benzimidazol-2-yl]-4,4-dideuterio-3,3-bis(trideuteriomethyl)pentanamide;N-[1-cyclobutyl-6-(2-hydroxypropan-2-yl)benzimidazol-2-yl]-2-(2,3,3-trifluoro-2-methylcyclobutyl)acetamide;N-[6-(difluoromethoxy)-7-fluoro-1-(1-methylcyclobutyl)benzimidazol-2-yl]-3,3-dimethylbutanamide;N-[6-(difluoromethoxy)-1-(1-methylcyclobutyl)benzimidazol-2-yl]-3,3-dimethylbutanamide?
The canonical SMILES for N-(6-bromo-1-cyclobutyl-4-fluorobenzimidazol-2-yl)-3,3-dimethylbutanamide;N-(1-tert-butyl-6-cyano-4-fluorobenzimidazol-2-yl)-3-(2-fluorophenyl)-3-hydroxybutanamide;N-(1-tert-butyl-4,7-difluoro-6-isocyanobenzimidazol-2-yl)-3,3-dimethylbutanamide;N-(5-chloro-6-cyano-1-cyclobutylbenzimidazol-2-yl)-3-hydroxy-3-phenylbutanamide;N-(6-cyano-1-cyclobutyl-7-fluorobenzimidazol-2-yl)-5,5-difluoro-3,3-dimethylhexanamide;N-(6-cyano-1-cyclobutyl-5-fluorobenzimidazol-2-yl)-3-hydroxy-3-phenylbutanamide;N-[6-cyano-1-(cyclopropylmethyl)benzimidazol-2-yl]-3-hydroxy-3-phenylbutanamide;N-[1-cyclobutyl-4-fluoro-6-(1-hydroxycyclobutyl)benzimidazol-2-yl]-3,3-dimethylbutanamide;N-[1-cyclobutyl-4-fluoro-6-(2-hydroxypropan-2-yl)benzimidazol-2-yl]-4,4-dideuterio-3,3-bis(trideuteriomethyl)pentanamide;N-[1-cyclobutyl-6-(2-hydroxypropan-2-yl)benzimidazol-2-yl]-2-(2,3,3-trifluoro-2-methylcyclobutyl)acetamide;N-[6-(difluoromethoxy)-7-fluoro-1-(1-methylcyclobutyl)benzimidazol-2-yl]-3,3-dimethylbutanamide;N-[6-(difluoromethoxy)-1-(1-methylcyclobutyl)benzimidazol-2-yl]-3,3-dimethylbutanamide is CC(C)(C)CC(=O)Nc1nc2c(F)cc(Br)cc2n1C1CCC1.CC(C)(C)CC(=O)Nc1nc2c(F)cc(C3(O)CCC3)cc2n1C1CCC1.CC(C)(C)CC(=O)Nc1nc2ccc(OC(F)F)c(F)c2n1C1(C)CCC1.CC(C)(C)CC(=O)Nc1nc2ccc(OC(F)F)cc2n1C1(C)CCC1.CC(C)(O)c1ccc2nc(NC(=O)CC3CC(F)(F)C3(C)F)n(C3CCC3)c2c1.CC(F)(F)CC(C)(C)CC(=O)Nc1nc2ccc(C#N)c(F)c2n1C1CCC1.CC(O)(CC(=O)Nc1nc2c(F)cc(C#N)cc2n1C(C)(C)C)c1ccccc1F.CC(O)(CC(=O)Nc1nc2cc(Cl)c(C#N)cc2n1C1CCC1)c1ccccc1.CC(O)(CC(=O)Nc1nc2cc(F)c(C#N)cc2n1C1CCC1)c1ccccc1.CC(O)(CC(=O)Nc1nc2ccc(C#N)cc2n1CC1CC1)c1ccccc1.[2H]C([2H])([2H])C(CC(=O)Nc1nc2c(F)cc(C(C)(C)O)cc2n1C1CCC1)(C([2H])([2H])[2H])C([2H])([2H])C.[C-]#[N+]c1cc(F)c2nc(NC(=O)CC(C)(C)C)n(C(C)(C)C)c2c1F.
What is the InChIKey of N-(6-bromo-1-cyclobutyl-4-fluorobenzimidazol-2-yl)-3,3-dimethylbutanamide;N-(1-tert-butyl-6-cyano-4-fluorobenzimidazol-2-yl)-3-(2-fluorophenyl)-3-hydroxybutanamide;N-(1-tert-butyl-4,7-difluoro-6-isocyanobenzimidazol-2-yl)-3,3-dimethylbutanamide;N-(5-chloro-6-cyano-1-cyclobutylbenzimidazol-2-yl)-3-hydroxy-3-phenylbutanamide;N-(6-cyano-1-cyclobutyl-7-fluorobenzimidazol-2-yl)-5,5-difluoro-3,3-dimethylhexanamide;N-(6-cyano-1-cyclobutyl-5-fluorobenzimidazol-2-yl)-3-hydroxy-3-phenylbutanamide;N-[6-cyano-1-(cyclopropylmethyl)benzimidazol-2-yl]-3-hydroxy-3-phenylbutanamide;N-[1-cyclobutyl-4-fluoro-6-(1-hydroxycyclobutyl)benzimidazol-2-yl]-3,3-dimethylbutanamide;N-[1-cyclobutyl-4-fluoro-6-(2-hydroxypropan-2-yl)benzimidazol-2-yl]-4,4-dideuterio-3,3-bis(trideuteriomethyl)pentanamide;N-[1-cyclobutyl-6-(2-hydroxypropan-2-yl)benzimidazol-2-yl]-2-(2,3,3-trifluoro-2-methylcyclobutyl)acetamide;N-[6-(difluoromethoxy)-7-fluoro-1-(1-methylcyclobutyl)benzimidazol-2-yl]-3,3-dimethylbutanamide;N-[6-(difluoromethoxy)-1-(1-methylcyclobutyl)benzimidazol-2-yl]-3,3-dimethylbutanamide?
The InChIKey is BETBEUWDADQVIK-HPIXPNRJSA-N. The full InChI is InChI=1S/C22H21ClN4O2.C22H22F2N4O2.C22H21FN4O2.C22H22N4O2.C21H26F3N3O2.C21H28FN3O2.C21H30FN3O2.C20H23F3N4O.C19H24F3N3O2.C19H25F2N3O2.C18H22F2N4O.C17H21BrFN3O/c1-22(29,15-6-3-2-4-7-15)12-20(28)26-21-25-18-11-17(23)14(13-24)10-19(18)27(21)16-8-5-9-16;1-21(2,3)28-17-10-13(12-25)9-16(24)19(17)27-20(28)26-18(29)11-22(4,30)14-7-5-6-8-15(14)23;1-22(29,15-6-3-2-4-7-15)12-20(28)26-21-25-18-11-17(23)14(13-24)10-19(18)27(21)16-8-5-9-16;1-22(28,17-5-3-2-4-6-17)12-20(27)25-21-24-18-10-9-16(13-23)11-19(18)26(21)14-15-7-8-15;1-19(2,29)12-7-8-15-16(9-12)27(14-5-4-6-14)18(25-15)26-17(28)10-13-11-21(23,24)20(13,3)22;1-20(2,3)12-17(26)23-19-24-18-15(22)10-13(21(27)8-5-9-21)11-16(18)25(19)14-6-4-7-14;1-6-20(2,3)12-17(26)23-19-24-18-15(22)10-13(21(4,5)27)11-16(18)25(19)14-8-7-9-14;1-19(2,11-20(3,22)23)9-15(28)26-18-25-14-8-7-12(10-24)16(21)17(14)27(18)13-5-4-6-13;1-18(2,3)10-13(26)24-17-23-11-6-7-12(27-16(21)22)14(20)15(11)25(17)19(4)8-5-9-19;1-18(2,3)11-15(25)23-17-22-13-7-6-12(26-16(20)21)10-14(13)24(17)19(4)8-5-9-19;1-17(2,3)9-12(25)22-16-23-14-10(19)8-11(21-7)13(20)15(14)24(16)18(4,5)6;1-17(2,3)9-14(23)20-16-21-15-12(19)7-10(18)8-13(15)22(16)11-5-4-6-11/h2-4,6-7,10-11,16,29H,5,8-9,12H2,1H3,(H,25,26,28);5-10,30H,11H2,1-4H3,(H,26,27,29);2-4,6-7,10-11,16,29H,5,8-9,12H2,1H3,(H,25,26,28);2-6,9-11,15,28H,7-8,12,14H2,1H3,(H,24,25,27);7-9,13-14,29H,4-6,10-11H2,1-3H3,(H,25,26,28);10-11,14,27H,4-9,12H2,1-3H3,(H,23,24,26);10-11,14,27H,6-9,12H2,1-5H3,(H,23,24,26);7-8,13H,4-6,9,11H2,1-3H3,(H,25,26,28);6-7,16H,5,8-10H2,1-4H3,(H,23,24,26);6-7,10,16H,5,8-9,11H2,1-4H3,(H,22,23,25);8H,9H2,1-6H3,(H,22,23,25);7-8,11H,4-6,9H2,1-3H3,(H,20,21,23)/i;;;;;;2D3,3D3,6D2;;;;;.
What are the key properties of N-(6-bromo-1-cyclobutyl-4-fluorobenzimidazol-2-yl)-3,3-dimethylbutanamide;N-(1-tert-butyl-6-cyano-4-fluorobenzimidazol-2-yl)-3-(2-fluorophenyl)-3-hydroxybutanamide;N-(1-tert-butyl-4,7-difluoro-6-isocyanobenzimidazol-2-yl)-3,3-dimethylbutanamide;N-(5-chloro-6-cyano-1-cyclobutylbenzimidazol-2-yl)-3-hydroxy-3-phenylbutanamide;N-(6-cyano-1-cyclobutyl-7-fluorobenzimidazol-2-yl)-5,5-difluoro-3,3-dimethylhexanamide;N-(6-cyano-1-cyclobutyl-5-fluorobenzimidazol-2-yl)-3-hydroxy-3-phenylbutanamide;N-[6-cyano-1-(cyclopropylmethyl)benzimidazol-2-yl]-3-hydroxy-3-phenylbutanamide;N-[1-cyclobutyl-4-fluoro-6-(1-hydroxycyclobutyl)benzimidazol-2-yl]-3,3-dimethylbutanamide;N-[1-cyclobutyl-4-fluoro-6-(2-hydroxypropan-2-yl)benzimidazol-2-yl]-4,4-dideuterio-3,3-bis(trideuteriomethyl)pentanamide;N-[1-cyclobutyl-6-(2-hydroxypropan-2-yl)benzimidazol-2-yl]-2-(2,3,3-trifluoro-2-methylcyclobutyl)acetamide;N-[6-(difluoromethoxy)-7-fluoro-1-(1-methylcyclobutyl)benzimidazol-2-yl]-3,3-dimethylbutanamide;N-[6-(difluoromethoxy)-1-(1-methylcyclobutyl)benzimidazol-2-yl]-3,3-dimethylbutanamide?
N-(6-bromo-1-cyclobutyl-4-fluorobenzimidazol-2-yl)-3,3-dimethylbutanamide;N-(1-tert-butyl-6-cyano-4-fluorobenzimidazol-2-yl)-3-(2-fluorophenyl)-3-hydroxybutanamide;N-(1-tert-butyl-4,7-difluoro-6-isocyanobenzimidazol-2-yl)-3,3-dimethylbutanamide;N-(5-chloro-6-cyano-1-cyclobutylbenzimidazol-2-yl)-3-hydroxy-3-phenylbutanamide;N-(6-cyano-1-cyclobutyl-7-fluorobenzimidazol-2-yl)-5,5-difluoro-3,3-dimethylhexanamide;N-(6-cyano-1-cyclobutyl-5-fluorobenzimidazol-2-yl)-3-hydroxy-3-phenylbutanamide;N-[6-cyano-1-(cyclopropylmethyl)benzimidazol-2-yl]-3-hydroxy-3-phenylbutanamide;N-[1-cyclobutyl-4-fluoro-6-(1-hydroxycyclobutyl)benzimidazol-2-yl]-3,3-dimethylbutanamide;N-[1-cyclobutyl-4-fluoro-6-(2-hydroxypropan-2-yl)benzimidazol-2-yl]-4,4-dideuterio-3,3-bis(trideuteriomethyl)pentanamide;N-[1-cyclobutyl-6-(2-hydroxypropan-2-yl)benzimidazol-2-yl]-2-(2,3,3-trifluoro-2-methylcyclobutyl)acetamide;N-[6-(difluoromethoxy)-7-fluoro-1-(1-methylcyclobutyl)benzimidazol-2-yl]-3,3-dimethylbutanamide;N-[6-(difluoromethoxy)-1-(1-methylcyclobutyl)benzimidazol-2-yl]-3,3-dimethylbutanamide has a molecular weight of 4626.60 g/mol, XLogP of 55.67, 58 rotatable bonds, 19 hydrogen bond donors, and 50 hydrogen bond acceptors.
Where does this data come from?
All data for N-(6-bromo-1-cyclobutyl-4-fluorobenzimidazol-2-yl)-3,3-dimethylbutanamide;N-(1-tert-butyl-6-cyano-4-fluorobenzimidazol-2-yl)-3-(2-fluorophenyl)-3-hydroxybutanamide;N-(1-tert-butyl-4,7-difluoro-6-isocyanobenzimidazol-2-yl)-3,3-dimethylbutanamide;N-(5-chloro-6-cyano-1-cyclobutylbenzimidazol-2-yl)-3-hydroxy-3-phenylbutanamide;N-(6-cyano-1-cyclobutyl-7-fluorobenzimidazol-2-yl)-5,5-difluoro-3,3-dimethylhexanamide;N-(6-cyano-1-cyclobutyl-5-fluorobenzimidazol-2-yl)-3-hydroxy-3-phenylbutanamide;N-[6-cyano-1-(cyclopropylmethyl)benzimidazol-2-yl]-3-hydroxy-3-phenylbutanamide;N-[1-cyclobutyl-4-fluoro-6-(1-hydroxycyclobutyl)benzimidazol-2-yl]-3,3-dimethylbutanamide;N-[1-cyclobutyl-4-fluoro-6-(2-hydroxypropan-2-yl)benzimidazol-2-yl]-4,4-dideuterio-3,3-bis(trideuteriomethyl)pentanamide;N-[1-cyclobutyl-6-(2-hydroxypropan-2-yl)benzimidazol-2-yl]-2-(2,3,3-trifluoro-2-methylcyclobutyl)acetamide;N-[6-(difluoromethoxy)-7-fluoro-1-(1-methylcyclobutyl)benzimidazol-2-yl]-3,3-dimethylbutanamide;N-[6-(difluoromethoxy)-1-(1-methylcyclobutyl)benzimidazol-2-yl]-3,3-dimethylbutanamide is sourced from PubChem (CID 157326182), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).