1-[(3S)-3-methoxy-1-[2-oxo-2-[1-(5-pyrimidin-2-yl-2-pyridinyl)piperidin-4-yl]ethyl]pyrrolidin-3-yl]-2-[3-(6-propan-2-yloxy-3-pyridinyl)-1H-indazol-5-yl]ethanone;1-[(3S)-3-methoxy-1-[2-oxo-2-[1-(1,3-thiazol-2-yl)piperidin-4-yl]ethyl]pyrrolidin-3-yl]-2-[3-(6-propan-2-yloxy-3-pyridinyl)-1H-indazol-5-yl]ethanone;2-[3-(2-methyl-4-pyridinyl)-1H-indazol-5-yl]-1-[(3S)-3-methylsulfanyl-1-[2-oxo-2-[1-(5-pyrimidin-2-yl-2-pyridinyl)piperidin-4-yl]ethyl]pyrrolidin-3-yl]ethanone;2-[3-(2-methyl-4-pyridinyl)-1H-indazol-5-yl]-1-[(3S)-3-methylsulfanyl-1-[2-oxo-2-[1-(1,3-thiazol-2-yl)piperidin-4-yl]ethyl]pyrrolidin-3-yl]ethanone;1-[(3S)-3-methylsulfanyl-1-[2-oxo-2-[1-(5-pyrimidin-2-yl-2-pyridinyl)piperidin-4-yl]ethyl]pyrrolidin-3-yl]-2-[3-[2-(trifluoromethyl)-4-pyridinyl]-1H-indazol-5-yl]ethanone

C172H187F3N36O14S5 — CID 157330137

About 1-[(3S)-3-methoxy-1-[2-oxo-2-[1-(5-pyrimidin-2-yl-2-pyridinyl)piperidin-4-yl]ethyl]pyrrolidin-3-yl]-2-[3-(6-propan-2-yloxy-3-pyridinyl)-1H-indazol-5-yl]ethanone;1-[(3S)-3-methoxy-1-[2-oxo-2-[1-(1,3-thiazol-2-yl)piperidin-4-yl]ethyl]pyrrolidin-3-yl]-2-[3-(6-propan-2-yloxy-3-pyridinyl)-1H-indazol-5-yl]ethanone;2-[3-(2-methyl-4-pyridinyl)-1H-indazol-5-yl]-1-[(3S)-3-methylsulfanyl-1-[2-oxo-2-[1-(5-pyrimidin-2-yl-2-pyridinyl)piperidin-4-yl]ethyl]pyrrolidin-3-yl]ethanone;2-[3-(2-methyl-4-pyridinyl)-1H-indazol-5-yl]-1-[(3S)-3-methylsulfanyl-1-[2-oxo-2-[1-(1,3-thiazol-2-yl)piperidin-4-yl]ethyl]pyrrolidin-3-yl]ethanone;1-[(3S)-3-methylsulfanyl-1-[2-oxo-2-[1-(5-pyrimidin-2-yl-2-pyridinyl)piperidin-4-yl]ethyl]pyrrolidin-3-yl]-2-[3-[2-(trifluoromethyl)-4-pyridinyl]-1H-indazol-5-yl]ethanone

1-[(3S)-3-methoxy-1-[2-oxo-2-[1-(5-pyrimidin-2-yl-2-pyridinyl)piperidin-4-yl]ethyl]pyrrolidin-3-yl]-2-[3-(6-propan-2-yloxy-3-pyridinyl)-1H-indazol-5-yl]ethanone;1-[(3S)-3-methoxy-1-[2-oxo-2-[1-(1,3-thiazol-2-yl)piperidin-4-yl]ethyl]pyrrolidin-3-yl]-2-[3-(6-propan-2-yloxy-3-pyridinyl)-1H-indazol-5-yl]ethanone;2-[3-(2-methyl-4-pyridinyl)-1H-indazol-5-yl]-1-[(3S)-3-methylsulfanyl-1-[2-oxo-2-[1-(5-pyrimidin-2-yl-2-pyridinyl)piperidin-4-yl]ethyl]pyrrolidin-3-yl]ethanone;2-[3-(2-methyl-4-pyridinyl)-1H-indazol-5-yl]-1-[(3S)-3-methylsulfanyl-1-[2-oxo-2-[1-(1,3-thiazol-2-yl)piperidin-4-yl]ethyl]pyrrolidin-3-yl]ethanone;1-[(3S)-3-methylsulfanyl-1-[2-oxo-2-[1-(5-pyrimidin-2-yl-2-pyridinyl)piperidin-4-yl]ethyl]pyrrolidin-3-yl]-2-[3-[2-(trifluoromethyl)-4-pyridinyl]-1H-indazol-5-yl]ethanone (PubChem CID 157330137) has the molecular formula C172H187F3N36O14S5 and a molecular weight of 3199.95 g/mol. Its IUPAC name is 1-[(3S)-3-methoxy-1-[2-oxo-2-[1-(5-pyrimidin-2-yl-2-pyridinyl)piperidin-4-yl]ethyl]pyrrolidin-3-yl]-2-[3-(6-propan-2-yloxy-3-pyridinyl)-1H-indazol-5-yl]ethanone;1-[(3S)-3-methoxy-1-[2-oxo-2-[1-(1,3-thiazol-2-yl)piperidin-4-yl]ethyl]pyrrolidin-3-yl]-2-[3-(6-propan-2-yloxy-3-pyridinyl)-1H-indazol-5-yl]ethanone;2-[3-(2-methyl-4-pyridinyl)-1H-indazol-5-yl]-1-[(3S)-3-methylsulfanyl-1-[2-oxo-2-[1-(5-pyrimidin-2-yl-2-pyridinyl)piperidin-4-yl]ethyl]pyrrolidin-3-yl]ethanone;2-[3-(2-methyl-4-pyridinyl)-1H-indazol-5-yl]-1-[(3S)-3-methylsulfanyl-1-[2-oxo-2-[1-(1,3-thiazol-2-yl)piperidin-4-yl]ethyl]pyrrolidin-3-yl]ethanone;1-[(3S)-3-methylsulfanyl-1-[2-oxo-2-[1-(5-pyrimidin-2-yl-2-pyridinyl)piperidin-4-yl]ethyl]pyrrolidin-3-yl]-2-[3-[2-(trifluoromethyl)-4-pyridinyl]-1H-indazol-5-yl]ethanone.

Molecular Properties

• Compound Name: 1-[(3S)-3-methoxy-1-[2-oxo-2-[1-(5-pyrimidin-2-yl-2-pyridinyl)piperidin-4-yl]ethyl]pyrrolidin-3-yl]-2-[3-(6-propan-2-yloxy-3-pyridinyl)-1H-indazol-5-yl]ethanone;1-[(3S)-3-methoxy-1-[2-oxo-2-[1-(1,3-thiazol-2-yl)piperidin-4-yl]ethyl]pyrrolidin-3-yl]-2-[3-(6-propan-2-yloxy-3-pyridinyl)-1H-indazol-5-yl]ethanone;2-[3-(2-methyl-4-pyridinyl)-1H-indazol-5-yl]-1-[(3S)-3-methylsulfanyl-1-[2-oxo-2-[1-(5-pyrimidin-2-yl-2-pyridinyl)piperidin-4-yl]ethyl]pyrrolidin-3-yl]ethanone;2-[3-(2-methyl-4-pyridinyl)-1H-indazol-5-yl]-1-[(3S)-3-methylsulfanyl-1-[2-oxo-2-[1-(1,3-thiazol-2-yl)piperidin-4-yl]ethyl]pyrrolidin-3-yl]ethanone;1-[(3S)-3-methylsulfanyl-1-[2-oxo-2-[1-(5-pyrimidin-2-yl-2-pyridinyl)piperidin-4-yl]ethyl]pyrrolidin-3-yl]-2-[3-[2-(trifluoromethyl)-4-pyridinyl]-1H-indazol-5-yl]ethanone
• PubChem CID: 157330137
• Molecular Formula: C172H187F3N36O14S5
• Molecular Weight: 3199.95 g/mol
• Exact Mass: 3197.36
• IUPAC Name: 1-[(3S)-3-methoxy-1-[2-oxo-2-[1-(5-pyrimidin-2-yl-2-pyridinyl)piperidin-4-yl]ethyl]pyrrolidin-3-yl]-2-[3-(6-propan-2-yloxy-3-pyridinyl)-1H-indazol-5-yl]ethanone;1-[(3S)-3-methoxy-1-[2-oxo-2-[1-(1,3-thiazol-2-yl)piperidin-4-yl]ethyl]pyrrolidin-3-yl]-2-[3-(6-propan-2-yloxy-3-pyridinyl)-1H-indazol-5-yl]ethanone;2-[3-(2-methyl-4-pyridinyl)-1H-indazol-5-yl]-1-[(3S)-3-methylsulfanyl-1-[2-oxo-2-[1-(5-pyrimidin-2-yl-2-pyridinyl)piperidin-4-yl]ethyl]pyrrolidin-3-yl]ethanone;2-[3-(2-methyl-4-pyridinyl)-1H-indazol-5-yl]-1-[(3S)-3-methylsulfanyl-1-[2-oxo-2-[1-(1,3-thiazol-2-yl)piperidin-4-yl]ethyl]pyrrolidin-3-yl]ethanone;1-[(3S)-3-methylsulfanyl-1-[2-oxo-2-[1-(5-pyrimidin-2-yl-2-pyridinyl)piperidin-4-yl]ethyl]pyrrolidin-3-yl]-2-[3-[2-(trifluoromethyl)-4-pyridinyl]-1H-indazol-5-yl]ethanone
• SMILES: CO[C@@]1(C(=O)Cc2ccc3[nH]nc(-c4ccc(OC(C)C)nc4)c3c2)CCN(CC(=O)C2CCN(c3ccc(-c4ncccn4)cn3)CC2)C1.CO[C@@]1(C(=O)Cc2ccc3[nH]nc(-c4ccc(OC(C)C)nc4)c3c2)CCN(CC(=O)C2CCN(c3nccs3)CC2)C1.CS[C@@]1(C(=O)Cc2ccc3[nH]nc(-c4ccnc(C(F)(F)F)c4)c3c2)CCN(CC(=O)C2CCN(c3ccc(-c4ncccn4)cn3)CC2)C1.CS[C@@]1(C(=O)Cc2ccc3[nH]nc(-c4ccnc(C)c4)c3c2)CCN(CC(=O)C2CCN(c3ccc(-c4ncccn4)cn3)CC2)C1.CS[C@@]1(C(=O)Cc2ccc3[nH]nc(-c4ccnc(C)c4)c3c2)CCN(CC(=O)C2CCN(c3nccs3)CC2)C1
• InChI: InChI=1S/C38H42N8O4.C36H35F3N8O2S.C36H38N8O2S.C32H38N6O4S.C30H34N6O2S2/c1-25(2)50-35-10-7-28(21-42-35)36-30-19-26(5-8-31(30)43-44-36)20-33(48)38(49-3)13-18-45(24-38)23-32(47)27-11-16-46(17-12-27)34-9-6-29(22-41-34)37-39-14-4-15-40-37;1-50-35(31(49)18-23-3-5-28-27(17-23)33(45-44-28)25-7-13-40-30(19-25)36(37,38)39)10-16-46(22-35)21-29(48)24-8-14-47(15-9-24)32-6-4-26(20-43-32)34-41-11-2-12-42-34;1-24-18-27(8-14-37-24)34-29-19-25(4-6-30(29)41-42-34)20-32(46)36(47-2)11-17-43(23-36)22-31(45)26-9-15-44(16-10-26)33-7-5-28(21-40-33)35-38-12-3-13-39-35;1-21(2)42-29-7-5-24(18-34-29)30-25-16-22(4-6-26(25)35-36-30)17-28(40)32(41-3)10-14-37(20-32)19-27(39)23-8-12-38(13-9-23)31-33-11-15-43-31;1-20-15-23(5-9-31-20)28-24-16-21(3-4-25(24)33-34-28)17-27(38)30(39-2)8-13-35(19-30)18-26(37)22-6-11-36(12-7-22)29-32-10-14-40-29/h4-10,14-15,19,21-22,25,27H,11-13,16-18,20,23-24H2,1-3H3,(H,43,44);2-7,11-13,17,19-20,24H,8-10,14-16,18,21-22H2,1H3,(H,44,45);3-8,12-14,18-19,21,26H,9-11,15-17,20,22-23H2,1-2H3,(H,41,42);4-7,11,15-16,18,21,23H,8-10,12-14,17,19-20H2,1-3H3,(H,35,36);3-5,9-10,14-16,22H,6-8,11-13,17-19H2,1-2H3,(H,33,34)/t38-;35-;36-;32-;30-/m00000/s1
• InChIKey: BFEPJJDVQPSLAX-KALQRQAOSA-N
• XLogP: 25.39
• TPSA: 589.66 Ų
• H-Bond Donors: 5
• H-Bond Acceptors: 50
• Rotatable Bonds: 52
• Heavy Atoms: 230
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	3199.95
LogP ≤ 5	25.39
H-Bond Donors ≤ 5	5
H-Bond Acceptors ≤ 10	50

Frequently Asked Questions

What is the IUPAC name of 1-[(3S)-3-methoxy-1-[2-oxo-2-[1-(5-pyrimidin-2-yl-2-pyridinyl)piperidin-4-yl]ethyl]pyrrolidin-3-yl]-2-[3-(6-propan-2-yloxy-3-pyridinyl)-1H-indazol-5-yl]ethanone;1-[(3S)-3-methoxy-1-[2-oxo-2-[1-(1,3-thiazol-2-yl)piperidin-4-yl]ethyl]pyrrolidin-3-yl]-2-[3-(6-propan-2-yloxy-3-pyridinyl)-1H-indazol-5-yl]ethanone;2-[3-(2-methyl-4-pyridinyl)-1H-indazol-5-yl]-1-[(3S)-3-methylsulfanyl-1-[2-oxo-2-[1-(5-pyrimidin-2-yl-2-pyridinyl)piperidin-4-yl]ethyl]pyrrolidin-3-yl]ethanone;2-[3-(2-methyl-4-pyridinyl)-1H-indazol-5-yl]-1-[(3S)-3-methylsulfanyl-1-[2-oxo-2-[1-(1,3-thiazol-2-yl)piperidin-4-yl]ethyl]pyrrolidin-3-yl]ethanone;1-[(3S)-3-methylsulfanyl-1-[2-oxo-2-[1-(5-pyrimidin-2-yl-2-pyridinyl)piperidin-4-yl]ethyl]pyrrolidin-3-yl]-2-[3-[2-(trifluoromethyl)-4-pyridinyl]-1H-indazol-5-yl]ethanone?

The IUPAC name of 1-[(3S)-3-methoxy-1-[2-oxo-2-[1-(5-pyrimidin-2-yl-2-pyridinyl)piperidin-4-yl]ethyl]pyrrolidin-3-yl]-2-[3-(6-propan-2-yloxy-3-pyridinyl)-1H-indazol-5-yl]ethanone;1-[(3S)-3-methoxy-1-[2-oxo-2-[1-(1,3-thiazol-2-yl)piperidin-4-yl]ethyl]pyrrolidin-3-yl]-2-[3-(6-propan-2-yloxy-3-pyridinyl)-1H-indazol-5-yl]ethanone;2-[3-(2-methyl-4-pyridinyl)-1H-indazol-5-yl]-1-[(3S)-3-methylsulfanyl-1-[2-oxo-2-[1-(5-pyrimidin-2-yl-2-pyridinyl)piperidin-4-yl]ethyl]pyrrolidin-3-yl]ethanone;2-[3-(2-methyl-4-pyridinyl)-1H-indazol-5-yl]-1-[(3S)-3-methylsulfanyl-1-[2-oxo-2-[1-(1,3-thiazol-2-yl)piperidin-4-yl]ethyl]pyrrolidin-3-yl]ethanone;1-[(3S)-3-methylsulfanyl-1-[2-oxo-2-[1-(5-pyrimidin-2-yl-2-pyridinyl)piperidin-4-yl]ethyl]pyrrolidin-3-yl]-2-[3-[2-(trifluoromethyl)-4-pyridinyl]-1H-indazol-5-yl]ethanone (CID 157330137) is 1-[(3S)-3-methoxy-1-[2-oxo-2-[1-(5-pyrimidin-2-yl-2-pyridinyl)piperidin-4-yl]ethyl]pyrrolidin-3-yl]-2-[3-(6-propan-2-yloxy-3-pyridinyl)-1H-indazol-5-yl]ethanone;1-[(3S)-3-methoxy-1-[2-oxo-2-[1-(1,3-thiazol-2-yl)piperidin-4-yl]ethyl]pyrrolidin-3-yl]-2-[3-(6-propan-2-yloxy-3-pyridinyl)-1H-indazol-5-yl]ethanone;2-[3-(2-methyl-4-pyridinyl)-1H-indazol-5-yl]-1-[(3S)-3-methylsulfanyl-1-[2-oxo-2-[1-(5-pyrimidin-2-yl-2-pyridinyl)piperidin-4-yl]ethyl]pyrrolidin-3-yl]ethanone;2-[3-(2-methyl-4-pyridinyl)-1H-indazol-5-yl]-1-[(3S)-3-methylsulfanyl-1-[2-oxo-2-[1-(1,3-thiazol-2-yl)piperidin-4-yl]ethyl]pyrrolidin-3-yl]ethanone;1-[(3S)-3-methylsulfanyl-1-[2-oxo-2-[1-(5-pyrimidin-2-yl-2-pyridinyl)piperidin-4-yl]ethyl]pyrrolidin-3-yl]-2-[3-[2-(trifluoromethyl)-4-pyridinyl]-1H-indazol-5-yl]ethanone.

What is the SMILES notation for 1-[(3S)-3-methoxy-1-[2-oxo-2-[1-(5-pyrimidin-2-yl-2-pyridinyl)piperidin-4-yl]ethyl]pyrrolidin-3-yl]-2-[3-(6-propan-2-yloxy-3-pyridinyl)-1H-indazol-5-yl]ethanone;1-[(3S)-3-methoxy-1-[2-oxo-2-[1-(1,3-thiazol-2-yl)piperidin-4-yl]ethyl]pyrrolidin-3-yl]-2-[3-(6-propan-2-yloxy-3-pyridinyl)-1H-indazol-5-yl]ethanone;2-[3-(2-methyl-4-pyridinyl)-1H-indazol-5-yl]-1-[(3S)-3-methylsulfanyl-1-[2-oxo-2-[1-(5-pyrimidin-2-yl-2-pyridinyl)piperidin-4-yl]ethyl]pyrrolidin-3-yl]ethanone;2-[3-(2-methyl-4-pyridinyl)-1H-indazol-5-yl]-1-[(3S)-3-methylsulfanyl-1-[2-oxo-2-[1-(1,3-thiazol-2-yl)piperidin-4-yl]ethyl]pyrrolidin-3-yl]ethanone;1-[(3S)-3-methylsulfanyl-1-[2-oxo-2-[1-(5-pyrimidin-2-yl-2-pyridinyl)piperidin-4-yl]ethyl]pyrrolidin-3-yl]-2-[3-[2-(trifluoromethyl)-4-pyridinyl]-1H-indazol-5-yl]ethanone?

The canonical SMILES for 1-[(3S)-3-methoxy-1-[2-oxo-2-[1-(5-pyrimidin-2-yl-2-pyridinyl)piperidin-4-yl]ethyl]pyrrolidin-3-yl]-2-[3-(6-propan-2-yloxy-3-pyridinyl)-1H-indazol-5-yl]ethanone;1-[(3S)-3-methoxy-1-[2-oxo-2-[1-(1,3-thiazol-2-yl)piperidin-4-yl]ethyl]pyrrolidin-3-yl]-2-[3-(6-propan-2-yloxy-3-pyridinyl)-1H-indazol-5-yl]ethanone;2-[3-(2-methyl-4-pyridinyl)-1H-indazol-5-yl]-1-[(3S)-3-methylsulfanyl-1-[2-oxo-2-[1-(5-pyrimidin-2-yl-2-pyridinyl)piperidin-4-yl]ethyl]pyrrolidin-3-yl]ethanone;2-[3-(2-methyl-4-pyridinyl)-1H-indazol-5-yl]-1-[(3S)-3-methylsulfanyl-1-[2-oxo-2-[1-(1,3-thiazol-2-yl)piperidin-4-yl]ethyl]pyrrolidin-3-yl]ethanone;1-[(3S)-3-methylsulfanyl-1-[2-oxo-2-[1-(5-pyrimidin-2-yl-2-pyridinyl)piperidin-4-yl]ethyl]pyrrolidin-3-yl]-2-[3-[2-(trifluoromethyl)-4-pyridinyl]-1H-indazol-5-yl]ethanone is CO[C@@]1(C(=O)Cc2ccc3[nH]nc(-c4ccc(OC(C)C)nc4)c3c2)CCN(CC(=O)C2CCN(c3ccc(-c4ncccn4)cn3)CC2)C1.CO[C@@]1(C(=O)Cc2ccc3[nH]nc(-c4ccc(OC(C)C)nc4)c3c2)CCN(CC(=O)C2CCN(c3nccs3)CC2)C1.CS[C@@]1(C(=O)Cc2ccc3[nH]nc(-c4ccnc(C(F)(F)F)c4)c3c2)CCN(CC(=O)C2CCN(c3ccc(-c4ncccn4)cn3)CC2)C1.CS[C@@]1(C(=O)Cc2ccc3[nH]nc(-c4ccnc(C)c4)c3c2)CCN(CC(=O)C2CCN(c3ccc(-c4ncccn4)cn3)CC2)C1.CS[C@@]1(C(=O)Cc2ccc3[nH]nc(-c4ccnc(C)c4)c3c2)CCN(CC(=O)C2CCN(c3nccs3)CC2)C1.

What is the InChIKey of 1-[(3S)-3-methoxy-1-[2-oxo-2-[1-(5-pyrimidin-2-yl-2-pyridinyl)piperidin-4-yl]ethyl]pyrrolidin-3-yl]-2-[3-(6-propan-2-yloxy-3-pyridinyl)-1H-indazol-5-yl]ethanone;1-[(3S)-3-methoxy-1-[2-oxo-2-[1-(1,3-thiazol-2-yl)piperidin-4-yl]ethyl]pyrrolidin-3-yl]-2-[3-(6-propan-2-yloxy-3-pyridinyl)-1H-indazol-5-yl]ethanone;2-[3-(2-methyl-4-pyridinyl)-1H-indazol-5-yl]-1-[(3S)-3-methylsulfanyl-1-[2-oxo-2-[1-(5-pyrimidin-2-yl-2-pyridinyl)piperidin-4-yl]ethyl]pyrrolidin-3-yl]ethanone;2-[3-(2-methyl-4-pyridinyl)-1H-indazol-5-yl]-1-[(3S)-3-methylsulfanyl-1-[2-oxo-2-[1-(1,3-thiazol-2-yl)piperidin-4-yl]ethyl]pyrrolidin-3-yl]ethanone;1-[(3S)-3-methylsulfanyl-1-[2-oxo-2-[1-(5-pyrimidin-2-yl-2-pyridinyl)piperidin-4-yl]ethyl]pyrrolidin-3-yl]-2-[3-[2-(trifluoromethyl)-4-pyridinyl]-1H-indazol-5-yl]ethanone?

The InChIKey is BFEPJJDVQPSLAX-KALQRQAOSA-N. The full InChI is InChI=1S/C38H42N8O4.C36H35F3N8O2S.C36H38N8O2S.C32H38N6O4S.C30H34N6O2S2/c1-25(2)50-35-10-7-28(21-42-35)36-30-19-26(5-8-31(30)43-44-36)20-33(48)38(49-3)13-18-45(24-38)23-32(47)27-11-16-46(17-12-27)34-9-6-29(22-41-34)37-39-14-4-15-40-37;1-50-35(31(49)18-23-3-5-28-27(17-23)33(45-44-28)25-7-13-40-30(19-25)36(37,38)39)10-16-46(22-35)21-29(48)24-8-14-47(15-9-24)32-6-4-26(20-43-32)34-41-11-2-12-42-34;1-24-18-27(8-14-37-24)34-29-19-25(4-6-30(29)41-42-34)20-32(46)36(47-2)11-17-43(23-36)22-31(45)26-9-15-44(16-10-26)33-7-5-28(21-40-33)35-38-12-3-13-39-35;1-21(2)42-29-7-5-24(18-34-29)30-25-16-22(4-6-26(25)35-36-30)17-28(40)32(41-3)10-14-37(20-32)19-27(39)23-8-12-38(13-9-23)31-33-11-15-43-31;1-20-15-23(5-9-31-20)28-24-16-21(3-4-25(24)33-34-28)17-27(38)30(39-2)8-13-35(19-30)18-26(37)22-6-11-36(12-7-22)29-32-10-14-40-29/h4-10,14-15,19,21-22,25,27H,11-13,16-18,20,23-24H2,1-3H3,(H,43,44);2-7,11-13,17,19-20,24H,8-10,14-16,18,21-22H2,1H3,(H,44,45);3-8,12-14,18-19,21,26H,9-11,15-17,20,22-23H2,1-2H3,(H,41,42);4-7,11,15-16,18,21,23H,8-10,12-14,17,19-20H2,1-3H3,(H,35,36);3-5,9-10,14-16,22H,6-8,11-13,17-19H2,1-2H3,(H,33,34)/t38-;35-;36-;32-;30-/m00000/s1.

What are the key properties of 1-[(3S)-3-methoxy-1-[2-oxo-2-[1-(5-pyrimidin-2-yl-2-pyridinyl)piperidin-4-yl]ethyl]pyrrolidin-3-yl]-2-[3-(6-propan-2-yloxy-3-pyridinyl)-1H-indazol-5-yl]ethanone;1-[(3S)-3-methoxy-1-[2-oxo-2-[1-(1,3-thiazol-2-yl)piperidin-4-yl]ethyl]pyrrolidin-3-yl]-2-[3-(6-propan-2-yloxy-3-pyridinyl)-1H-indazol-5-yl]ethanone;2-[3-(2-methyl-4-pyridinyl)-1H-indazol-5-yl]-1-[(3S)-3-methylsulfanyl-1-[2-oxo-2-[1-(5-pyrimidin-2-yl-2-pyridinyl)piperidin-4-yl]ethyl]pyrrolidin-3-yl]ethanone;2-[3-(2-methyl-4-pyridinyl)-1H-indazol-5-yl]-1-[(3S)-3-methylsulfanyl-1-[2-oxo-2-[1-(1,3-thiazol-2-yl)piperidin-4-yl]ethyl]pyrrolidin-3-yl]ethanone;1-[(3S)-3-methylsulfanyl-1-[2-oxo-2-[1-(5-pyrimidin-2-yl-2-pyridinyl)piperidin-4-yl]ethyl]pyrrolidin-3-yl]-2-[3-[2-(trifluoromethyl)-4-pyridinyl]-1H-indazol-5-yl]ethanone?

1-[(3S)-3-methoxy-1-[2-oxo-2-[1-(5-pyrimidin-2-yl-2-pyridinyl)piperidin-4-yl]ethyl]pyrrolidin-3-yl]-2-[3-(6-propan-2-yloxy-3-pyridinyl)-1H-indazol-5-yl]ethanone;1-[(3S)-3-methoxy-1-[2-oxo-2-[1-(1,3-thiazol-2-yl)piperidin-4-yl]ethyl]pyrrolidin-3-yl]-2-[3-(6-propan-2-yloxy-3-pyridinyl)-1H-indazol-5-yl]ethanone;2-[3-(2-methyl-4-pyridinyl)-1H-indazol-5-yl]-1-[(3S)-3-methylsulfanyl-1-[2-oxo-2-[1-(5-pyrimidin-2-yl-2-pyridinyl)piperidin-4-yl]ethyl]pyrrolidin-3-yl]ethanone;2-[3-(2-methyl-4-pyridinyl)-1H-indazol-5-yl]-1-[(3S)-3-methylsulfanyl-1-[2-oxo-2-[1-(1,3-thiazol-2-yl)piperidin-4-yl]ethyl]pyrrolidin-3-yl]ethanone;1-[(3S)-3-methylsulfanyl-1-[2-oxo-2-[1-(5-pyrimidin-2-yl-2-pyridinyl)piperidin-4-yl]ethyl]pyrrolidin-3-yl]-2-[3-[2-(trifluoromethyl)-4-pyridinyl]-1H-indazol-5-yl]ethanone has a molecular weight of 3199.95 g/mol, XLogP of 25.39, 52 rotatable bonds, 5 hydrogen bond donors, and 50 hydrogen bond acceptors.

Where does this data come from?

All data for 1-[(3S)-3-methoxy-1-[2-oxo-2-[1-(5-pyrimidin-2-yl-2-pyridinyl)piperidin-4-yl]ethyl]pyrrolidin-3-yl]-2-[3-(6-propan-2-yloxy-3-pyridinyl)-1H-indazol-5-yl]ethanone;1-[(3S)-3-methoxy-1-[2-oxo-2-[1-(1,3-thiazol-2-yl)piperidin-4-yl]ethyl]pyrrolidin-3-yl]-2-[3-(6-propan-2-yloxy-3-pyridinyl)-1H-indazol-5-yl]ethanone;2-[3-(2-methyl-4-pyridinyl)-1H-indazol-5-yl]-1-[(3S)-3-methylsulfanyl-1-[2-oxo-2-[1-(5-pyrimidin-2-yl-2-pyridinyl)piperidin-4-yl]ethyl]pyrrolidin-3-yl]ethanone;2-[3-(2-methyl-4-pyridinyl)-1H-indazol-5-yl]-1-[(3S)-3-methylsulfanyl-1-[2-oxo-2-[1-(1,3-thiazol-2-yl)piperidin-4-yl]ethyl]pyrrolidin-3-yl]ethanone;1-[(3S)-3-methylsulfanyl-1-[2-oxo-2-[1-(5-pyrimidin-2-yl-2-pyridinyl)piperidin-4-yl]ethyl]pyrrolidin-3-yl]-2-[3-[2-(trifluoromethyl)-4-pyridinyl]-1H-indazol-5-yl]ethanone is sourced from PubChem (CID 157330137), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).