2-amino-5-[3,4-difluoro-5-(2-fluorophenyl)phenyl]-5-[6-(difluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3,4-difluoro-5-(4-fluorophenyl)phenyl]-5-[6-(difluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3,4-difluoro-5-(2-fluoropyrimidin-5-yl)phenyl]-5-[6-(difluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[6-(difluoromethyl)-2-pyridinyl]-5-[3,4-difluoro-5-(1,3-oxazol-4-yl)phenyl]-3-methylimidazol-4-one;2-amino-5-[6-(difluoromethyl)-2-pyridinyl]-5-(3,4-difluoro-5-phenylphenyl)-3-methylimidazol-4-one;2-amino-5-[6-(difluoromethyl)-2-pyridinyl]-5-(3,4-difluoro-5-pyrazin-2-ylphenyl)-3-methylimidazol-4-one;2-amino-5-[6-(difluoromethyl)-2-pyridinyl]-5-(3,4-difluoro-5-pyridazin-3-ylphenyl)-3-methylimidazol-4-one;2-amino-5-[6-(difluoromethyl)-2-pyridinyl]-5-(3,4-difluoro-5-pyridazin-4-ylphenyl)-3-methylimidazol-4-one;2-amino-5-[6-(difluoromethyl)-2-pyridinyl]-5-(3,4-difluoro-5-pyridin-2-ylphenyl)-3-methylimidazol-4-one;2-amino-5-[6-(difluoromethyl)-2-pyridinyl]-5-[3,4-difluoro-5-(1,3-thiazol-4-yl)phenyl]-3-methylimidazol-4-one;3-[5-[2-amino-4-[6-(difluoromethyl)-2-pyridinyl]-1-methyl-5-oxoimidazol-4-yl]-2,3-difluorophenyl]benzonitrile;5-[5-[2-amino-4-[6-(difluoromethyl)-2-pyridinyl]-1-methyl-5-oxoimidazol-4-yl]-2,3-difluorophenyl]pyridine-3-carbonitrile

C250H171F51N62O13S — CID 157336290

IUPAC2-amino-5-[3,4-difluoro-5-(2-fluorophenyl)phenyl]-5-[6-(difluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3,4-difluoro-5-(4-fluorophenyl)phenyl]-5-[6-(difluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3,4-difluoro-5-(2-fluoropyrimidin-5-yl)phenyl]-5-[6-(difluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[6-(difluoromethyl)-2-pyridinyl]-5-[3,4-difluoro-5-(1,3-oxazol-4-yl)phenyl]-3-methylimidazol-4-one;2-amino-5-[6-(difluoromethyl)-2-pyridinyl]-5-(3,4-difluoro-5-phenylphenyl)-3-methylimidazol-4-one;2-amino-5-[6-(difluoromethyl)-2-pyridinyl]-5-(3,4-difluoro-5-pyrazin-2-ylphenyl)-3-methylimidazol-4-one;2-amino-5-[6-(difluoromethyl)-2-pyridinyl]-5-(3,4-difluoro-5-pyridazin-3-ylphenyl)-3-methylimidazol-4-one;2-amino-5-[6-(difluoromethyl)-2-pyridinyl]-5-(3,4-difluoro-5-pyridazin-4-ylphenyl)-3-methylimidazol-4-one;2-amino-5-[6-(difluoromethyl)-2-pyridinyl]-5-(3,4-difluoro-5-pyridin-2-ylphenyl)-3-methylimidazol-4-one;2-amino-5-[6-(difluoromethyl)-2-pyridinyl]-5-[3,4-difluoro-5-(1,3-thiazol-4-yl)phenyl]-3-methylimidazol-4-one;3-[5-[2-amino-4-[6-(difluoromethyl)-2-pyridinyl]-1-methyl-5-oxoimidazol-4-yl]-2,3-difluorophenyl]benzonitrile;5-[5-[2-amino-4-[6-(difluoromethyl)-2-pyridinyl]-1-methyl-5-oxoimidazol-4-yl]-2,3-difluorophenyl]pyridine-3-carbonitrile
SMILESCN1C(=O)C(c2cc(F)c(F)c(-c3ccc(F)cc3)c2)(c2cccc(C(F)F)n2)N=C1N.CN1C(=O)C(c2cc(F)c(F)c(-c3cccc(C#N)c3)c2)(c2cccc(C(F)F)n2)N=C1N.CN1C(=O)C(c2cc(F)c(F)c(-c3ccccc3)c2)(c2cccc(C(F)F)n2)N=C1N.CN1C(=O)C(c2cc(F)c(F)c(-c3ccccc3F)c2)(c2cccc(C(F)F)n2)N=C1N.CN1C(=O)C(c2cc(F)c(F)c(-c3ccccn3)c2)(c2cccc(C(F)F)n2)N=C1N.CN1C(=O)C(c2cc(F)c(F)c(-c3cccnn3)c2)(c2cccc(C(F)F)n2)N=C1N.CN1C(=O)C(c2cc(F)c(F)c(-c3ccnnc3)c2)(c2cccc(C(F)F)n2)N=C1N.CN1C(=O)C(c2cc(F)c(F)c(-c3cnc(F)nc3)c2)(c2cccc(C(F)F)n2)N=C1N.CN1C(=O)C(c2cc(F)c(F)c(-c3cncc(C#N)c3)c2)(c2cccc(C(F)F)n2)N=C1N.CN1C(=O)C(c2cc(F)c(F)c(-c3cnccn3)c2)(c2cccc(C(F)F)n2)N=C1N.CN1C(=O)C(c2cc(F)c(F)c(-c3cocn3)c2)(c2cccc(C(F)F)n2)N=C1N.CN1C(=O)C(c2cc(F)c(F)c(-c3cscn3)c2)(c2cccc(C(F)F)n2)N=C1N
InChIInChI=1S/C23H15F4N5O.2C22H15F5N4O.C22H14F4N6O.C22H16F4N4O.C21H15F4N5O.C20H13F5N6O.3C20H14F4N6O.C19H13F4N5O2.C19H13F4N5OS/c1-32-21(33)23(31-22(32)29,18-7-3-6-17(30-18)20(26)27)14-9-15(19(25)16(24)10-14)13-5-2-4-12(8-13)11-28;1-31-20(32)22(30-21(31)28,17-8-4-7-16(29-17)19(26)27)11-9-13(18(25)15(24)10-11)12-5-2-3-6-14(12)23;1-31-20(32)22(30-21(31)28,17-4-2-3-16(29-17)19(26)27)12-9-14(18(25)15(24)10-12)11-5-7-13(23)8-6-11;1-32-20(33)22(31-21(32)28,17-4-2-3-16(30-17)19(25)26)13-6-14(18(24)15(23)7-13)12-5-11(8-27)9-29-10-12;1-30-20(31)22(29-21(30)27,17-9-5-8-16(28-17)19(25)26)13-10-14(18(24)15(23)11-13)12-6-3-2-4-7-12;1-30-19(31)21(29-20(30)26,16-7-4-6-15(28-16)18(24)25)11-9-12(17(23)13(22)10-11)14-5-2-3-8-27-14;1-31-17(32)20(30-19(31)26,14-4-2-3-13(29-14)16(23)24)10-5-11(15(22)12(21)6-10)9-7-27-18(25)28-8-9;1-30-18(31)20(28-19(30)25,15-6-2-4-14(27-15)17(23)24)10-8-11(16(22)12(21)9-10)13-5-3-7-26-29-13;1-30-18(31)20(29-19(30)25,15-4-2-3-13(28-15)17(23)24)10-7-11(16(22)12(21)8-10)14-9-26-5-6-27-14;1-30-18(31)20(29-19(30)25,15-4-2-3-14(28-15)17(23)24)11-7-12(16(22)13(21)8-11)10-5-6-26-27-9-10;2*1-28-17(29)19(27-18(28)24,14-4-2-3-12(26-14)16(22)23)9-5-10(13-7-30-8-25-13)15(21)11(20)6-9/h2-10,20H,1H3,(H2,29,31);2*2-10,19H,1H3,(H2,28,30);2-7,9-10,19H,1H3,(H2,28,31);2-11,19H,1H3,(H2,27,29);2-10,18H,1H3,(H2,26,29);2-8,16H,1H3,(H2,26,30);2-9,17H,1H3,(H2,25,28);2*2-9,17H,1H3,(H2,25,29);2*2-8,16H,1H3,(H2,24,27)
InChIKeyBFWKOFDSVCDLAI-UHFFFAOYSA-N
MW5252.50 g/mol
LogP40.49
Rot. Bonds48

About 2-amino-5-[3,4-difluoro-5-(2-fluorophenyl)phenyl]-5-[6-(difluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3,4-difluoro-5-(4-fluorophenyl)phenyl]-5-[6-(difluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3,4-difluoro-5-(2-fluoropyrimidin-5-yl)phenyl]-5-[6-(difluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[6-(difluoromethyl)-2-pyridinyl]-5-[3,4-difluoro-5-(1,3-oxazol-4-yl)phenyl]-3-methylimidazol-4-one;2-amino-5-[6-(difluoromethyl)-2-pyridinyl]-5-(3,4-difluoro-5-phenylphenyl)-3-methylimidazol-4-one;2-amino-5-[6-(difluoromethyl)-2-pyridinyl]-5-(3,4-difluoro-5-pyrazin-2-ylphenyl)-3-methylimidazol-4-one;2-amino-5-[6-(difluoromethyl)-2-pyridinyl]-5-(3,4-difluoro-5-pyridazin-3-ylphenyl)-3-methylimidazol-4-one;2-amino-5-[6-(difluoromethyl)-2-pyridinyl]-5-(3,4-difluoro-5-pyridazin-4-ylphenyl)-3-methylimidazol-4-one;2-amino-5-[6-(difluoromethyl)-2-pyridinyl]-5-(3,4-difluoro-5-pyridin-2-ylphenyl)-3-methylimidazol-4-one;2-amino-5-[6-(difluoromethyl)-2-pyridinyl]-5-[3,4-difluoro-5-(1,3-thiazol-4-yl)phenyl]-3-methylimidazol-4-one;3-[5-[2-amino-4-[6-(difluoromethyl)-2-pyridinyl]-1-methyl-5-oxoimidazol-4-yl]-2,3-difluorophenyl]benzonitrile;5-[5-[2-amino-4-[6-(difluoromethyl)-2-pyridinyl]-1-methyl-5-oxoimidazol-4-yl]-2,3-difluorophenyl]pyridine-3-carbonitrile

2-amino-5-[3,4-difluoro-5-(2-fluorophenyl)phenyl]-5-[6-(difluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3,4-difluoro-5-(4-fluorophenyl)phenyl]-5-[6-(difluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3,4-difluoro-5-(2-fluoropyrimidin-5-yl)phenyl]-5-[6-(difluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[6-(difluoromethyl)-2-pyridinyl]-5-[3,4-difluoro-5-(1,3-oxazol-4-yl)phenyl]-3-methylimidazol-4-one;2-amino-5-[6-(difluoromethyl)-2-pyridinyl]-5-(3,4-difluoro-5-phenylphenyl)-3-methylimidazol-4-one;2-amino-5-[6-(difluoromethyl)-2-pyridinyl]-5-(3,4-difluoro-5-pyrazin-2-ylphenyl)-3-methylimidazol-4-one;2-amino-5-[6-(difluoromethyl)-2-pyridinyl]-5-(3,4-difluoro-5-pyridazin-3-ylphenyl)-3-methylimidazol-4-one;2-amino-5-[6-(difluoromethyl)-2-pyridinyl]-5-(3,4-difluoro-5-pyridazin-4-ylphenyl)-3-methylimidazol-4-one;2-amino-5-[6-(difluoromethyl)-2-pyridinyl]-5-(3,4-difluoro-5-pyridin-2-ylphenyl)-3-methylimidazol-4-one;2-amino-5-[6-(difluoromethyl)-2-pyridinyl]-5-[3,4-difluoro-5-(1,3-thiazol-4-yl)phenyl]-3-methylimidazol-4-one;3-[5-[2-amino-4-[6-(difluoromethyl)-2-pyridinyl]-1-methyl-5-oxoimidazol-4-yl]-2,3-difluorophenyl]benzonitrile;5-[5-[2-amino-4-[6-(difluoromethyl)-2-pyridinyl]-1-methyl-5-oxoimidazol-4-yl]-2,3-difluorophenyl]pyridine-3-carbonitrile (PubChem CID 157336290) has the molecular formula C250H171F51N62O13S and a molecular weight of 5252.50 g/mol. Its IUPAC name is 2-amino-5-[3,4-difluoro-5-(2-fluorophenyl)phenyl]-5-[6-(difluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3,4-difluoro-5-(4-fluorophenyl)phenyl]-5-[6-(difluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3,4-difluoro-5-(2-fluoropyrimidin-5-yl)phenyl]-5-[6-(difluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[6-(difluoromethyl)-2-pyridinyl]-5-[3,4-difluoro-5-(1,3-oxazol-4-yl)phenyl]-3-methylimidazol-4-one;2-amino-5-[6-(difluoromethyl)-2-pyridinyl]-5-(3,4-difluoro-5-phenylphenyl)-3-methylimidazol-4-one;2-amino-5-[6-(difluoromethyl)-2-pyridinyl]-5-(3,4-difluoro-5-pyrazin-2-ylphenyl)-3-methylimidazol-4-one;2-amino-5-[6-(difluoromethyl)-2-pyridinyl]-5-(3,4-difluoro-5-pyridazin-3-ylphenyl)-3-methylimidazol-4-one;2-amino-5-[6-(difluoromethyl)-2-pyridinyl]-5-(3,4-difluoro-5-pyridazin-4-ylphenyl)-3-methylimidazol-4-one;2-amino-5-[6-(difluoromethyl)-2-pyridinyl]-5-(3,4-difluoro-5-pyridin-2-ylphenyl)-3-methylimidazol-4-one;2-amino-5-[6-(difluoromethyl)-2-pyridinyl]-5-[3,4-difluoro-5-(1,3-thiazol-4-yl)phenyl]-3-methylimidazol-4-one;3-[5-[2-amino-4-[6-(difluoromethyl)-2-pyridinyl]-1-methyl-5-oxoimidazol-4-yl]-2,3-difluorophenyl]benzonitrile;5-[5-[2-amino-4-[6-(difluoromethyl)-2-pyridinyl]-1-methyl-5-oxoimidazol-4-yl]-2,3-difluorophenyl]pyridine-3-carbonitrile.

Molecular Properties

Compound Name2-amino-5-[3,4-difluoro-5-(2-fluorophenyl)phenyl]-5-[6-(difluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3,4-difluoro-5-(4-fluorophenyl)phenyl]-5-[6-(difluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3,4-difluoro-5-(2-fluoropyrimidin-5-yl)phenyl]-5-[6-(difluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[6-(difluoromethyl)-2-pyridinyl]-5-[3,4-difluoro-5-(1,3-oxazol-4-yl)phenyl]-3-methylimidazol-4-one;2-amino-5-[6-(difluoromethyl)-2-pyridinyl]-5-(3,4-difluoro-5-phenylphenyl)-3-methylimidazol-4-one;2-amino-5-[6-(difluoromethyl)-2-pyridinyl]-5-(3,4-difluoro-5-pyrazin-2-ylphenyl)-3-methylimidazol-4-one;2-amino-5-[6-(difluoromethyl)-2-pyridinyl]-5-(3,4-difluoro-5-pyridazin-3-ylphenyl)-3-methylimidazol-4-one;2-amino-5-[6-(difluoromethyl)-2-pyridinyl]-5-(3,4-difluoro-5-pyridazin-4-ylphenyl)-3-methylimidazol-4-one;2-amino-5-[6-(difluoromethyl)-2-pyridinyl]-5-(3,4-difluoro-5-pyridin-2-ylphenyl)-3-methylimidazol-4-one;2-amino-5-[6-(difluoromethyl)-2-pyridinyl]-5-[3,4-difluoro-5-(1,3-thiazol-4-yl)phenyl]-3-methylimidazol-4-one;3-[5-[2-amino-4-[6-(difluoromethyl)-2-pyridinyl]-1-methyl-5-oxoimidazol-4-yl]-2,3-difluorophenyl]benzonitrile;5-[5-[2-amino-4-[6-(difluoromethyl)-2-pyridinyl]-1-methyl-5-oxoimidazol-4-yl]-2,3-difluorophenyl]pyridine-3-carbonitrile
PubChem CID157336290
Molecular FormulaC250H171F51N62O13S
Molecular Weight5252.50 g/mol
Exact Mass5249.35
IUPAC Name2-amino-5-[3,4-difluoro-5-(2-fluorophenyl)phenyl]-5-[6-(difluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3,4-difluoro-5-(4-fluorophenyl)phenyl]-5-[6-(difluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3,4-difluoro-5-(2-fluoropyrimidin-5-yl)phenyl]-5-[6-(difluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[6-(difluoromethyl)-2-pyridinyl]-5-[3,4-difluoro-5-(1,3-oxazol-4-yl)phenyl]-3-methylimidazol-4-one;2-amino-5-[6-(difluoromethyl)-2-pyridinyl]-5-(3,4-difluoro-5-phenylphenyl)-3-methylimidazol-4-one;2-amino-5-[6-(difluoromethyl)-2-pyridinyl]-5-(3,4-difluoro-5-pyrazin-2-ylphenyl)-3-methylimidazol-4-one;2-amino-5-[6-(difluoromethyl)-2-pyridinyl]-5-(3,4-difluoro-5-pyridazin-3-ylphenyl)-3-methylimidazol-4-one;2-amino-5-[6-(difluoromethyl)-2-pyridinyl]-5-(3,4-difluoro-5-pyridazin-4-ylphenyl)-3-methylimidazol-4-one;2-amino-5-[6-(difluoromethyl)-2-pyridinyl]-5-(3,4-difluoro-5-pyridin-2-ylphenyl)-3-methylimidazol-4-one;2-amino-5-[6-(difluoromethyl)-2-pyridinyl]-5-[3,4-difluoro-5-(1,3-thiazol-4-yl)phenyl]-3-methylimidazol-4-one;3-[5-[2-amino-4-[6-(difluoromethyl)-2-pyridinyl]-1-methyl-5-oxoimidazol-4-yl]-2,3-difluorophenyl]benzonitrile;5-[5-[2-amino-4-[6-(difluoromethyl)-2-pyridinyl]-1-methyl-5-oxoimidazol-4-yl]-2,3-difluorophenyl]pyridine-3-carbonitrile
SMILESCN1C(=O)C(c2cc(F)c(F)c(-c3ccc(F)cc3)c2)(c2cccc(C(F)F)n2)N=C1N.CN1C(=O)C(c2cc(F)c(F)c(-c3cccc(C#N)c3)c2)(c2cccc(C(F)F)n2)N=C1N.CN1C(=O)C(c2cc(F)c(F)c(-c3ccccc3)c2)(c2cccc(C(F)F)n2)N=C1N.CN1C(=O)C(c2cc(F)c(F)c(-c3ccccc3F)c2)(c2cccc(C(F)F)n2)N=C1N.CN1C(=O)C(c2cc(F)c(F)c(-c3ccccn3)c2)(c2cccc(C(F)F)n2)N=C1N.CN1C(=O)C(c2cc(F)c(F)c(-c3cccnn3)c2)(c2cccc(C(F)F)n2)N=C1N.CN1C(=O)C(c2cc(F)c(F)c(-c3ccnnc3)c2)(c2cccc(C(F)F)n2)N=C1N.CN1C(=O)C(c2cc(F)c(F)c(-c3cnc(F)nc3)c2)(c2cccc(C(F)F)n2)N=C1N.CN1C(=O)C(c2cc(F)c(F)c(-c3cncc(C#N)c3)c2)(c2cccc(C(F)F)n2)N=C1N.CN1C(=O)C(c2cc(F)c(F)c(-c3cnccn3)c2)(c2cccc(C(F)F)n2)N=C1N.CN1C(=O)C(c2cc(F)c(F)c(-c3cocn3)c2)(c2cccc(C(F)F)n2)N=C1N.CN1C(=O)C(c2cc(F)c(F)c(-c3cscn3)c2)(c2cccc(C(F)F)n2)N=C1N
InChIInChI=1S/C23H15F4N5O.2C22H15F5N4O.C22H14F4N6O.C22H16F4N4O.C21H15F4N5O.C20H13F5N6O.3C20H14F4N6O.C19H13F4N5O2.C19H13F4N5OS/c1-32-21(33)23(31-22(32)29,18-7-3-6-17(30-18)20(26)27)14-9-15(19(25)16(24)10-14)13-5-2-4-12(8-13)11-28;1-31-20(32)22(30-21(31)28,17-8-4-7-16(29-17)19(26)27)11-9-13(18(25)15(24)10-11)12-5-2-3-6-14(12)23;1-31-20(32)22(30-21(31)28,17-4-2-3-16(29-17)19(26)27)12-9-14(18(25)15(24)10-12)11-5-7-13(23)8-6-11;1-32-20(33)22(31-21(32)28,17-4-2-3-16(30-17)19(25)26)13-6-14(18(24)15(23)7-13)12-5-11(8-27)9-29-10-12;1-30-20(31)22(29-21(30)27,17-9-5-8-16(28-17)19(25)26)13-10-14(18(24)15(23)11-13)12-6-3-2-4-7-12;1-30-19(31)21(29-20(30)26,16-7-4-6-15(28-16)18(24)25)11-9-12(17(23)13(22)10-11)14-5-2-3-8-27-14;1-31-17(32)20(30-19(31)26,14-4-2-3-13(29-14)16(23)24)10-5-11(15(22)12(21)6-10)9-7-27-18(25)28-8-9;1-30-18(31)20(28-19(30)25,15-6-2-4-14(27-15)17(23)24)10-8-11(16(22)12(21)9-10)13-5-3-7-26-29-13;1-30-18(31)20(29-19(30)25,15-4-2-3-13(28-15)17(23)24)10-7-11(16(22)12(21)8-10)14-9-26-5-6-27-14;1-30-18(31)20(29-19(30)25,15-4-2-3-14(28-15)17(23)24)11-7-12(16(22)13(21)8-11)10-5-6-26-27-9-10;2*1-28-17(29)19(27-18(28)24,14-4-2-3-12(26-14)16(22)23)9-5-10(13-7-30-8-25-13)15(21)11(20)6-9/h2-10,20H,1H3,(H2,29,31);2*2-10,19H,1H3,(H2,28,30);2-7,9-10,19H,1H3,(H2,28,31);2-11,19H,1H3,(H2,27,29);2-10,18H,1H3,(H2,26,29);2-8,16H,1H3,(H2,26,30);2-9,17H,1H3,(H2,25,28);2*2-9,17H,1H3,(H2,25,29);2*2-8,16H,1H3,(H2,24,27)
InChIKeyBFWKOFDSVCDLAI-UHFFFAOYSA-N
XLogP40.49
TPSA1074.36 Ų
H-Bond Donors12
H-Bond Acceptors64
Rotatable Bonds48
Heavy Atoms377
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5005252.50
LogP ≤ 540.49
H-Bond Donors ≤ 512
H-Bond Acceptors ≤ 1064

Analyze 2-amino-5-[3,4-difluoro-5-(2-fluorophenyl)phenyl]-5-[6-(difluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3,4-difluoro-5-(4-fluorophenyl)phenyl]-5-[6-(difluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3,4-difluoro-5-(2-fluoropyrimidin-5-yl)phenyl]-5-[6-(difluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[6-(difluoromethyl)-2-pyridinyl]-5-[3,4-difluoro-5-(1,3-oxazol-4-yl)phenyl]-3-methylimidazol-4-one;2-amino-5-[6-(difluoromethyl)-2-pyridinyl]-5-(3,4-difluoro-5-phenylphenyl)-3-methylimidazol-4-one;2-amino-5-[6-(difluoromethyl)-2-pyridinyl]-5-(3,4-difluoro-5-pyrazin-2-ylphenyl)-3-methylimidazol-4-one;2-amino-5-[6-(difluoromethyl)-2-pyridinyl]-5-(3,4-difluoro-5-pyridazin-3-ylphenyl)-3-methylimidazol-4-one;2-amino-5-[6-(difluoromethyl)-2-pyridinyl]-5-(3,4-difluoro-5-pyridazin-4-ylphenyl)-3-methylimidazol-4-one;2-amino-5-[6-(difluoromethyl)-2-pyridinyl]-5-(3,4-difluoro-5-pyridin-2-ylphenyl)-3-methylimidazol-4-one;2-amino-5-[6-(difluoromethyl)-2-pyridinyl]-5-[3,4-difluoro-5-(1,3-thiazol-4-yl)phenyl]-3-methylimidazol-4-one;3-[5-[2-amino-4-[6-(difluoromethyl)-2-pyridinyl]-1-methyl-5-oxoimidazol-4-yl]-2,3-difluorophenyl]benzonitrile;5-[5-[2-amino-4-[6-(difluoromethyl)-2-pyridinyl]-1-methyl-5-oxoimidazol-4-yl]-2,3-difluorophenyl]pyridine-3-carbonitrile with MolForge

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Frequently Asked Questions

What is the IUPAC name of 2-amino-5-[3,4-difluoro-5-(2-fluorophenyl)phenyl]-5-[6-(difluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3,4-difluoro-5-(4-fluorophenyl)phenyl]-5-[6-(difluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3,4-difluoro-5-(2-fluoropyrimidin-5-yl)phenyl]-5-[6-(difluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[6-(difluoromethyl)-2-pyridinyl]-5-[3,4-difluoro-5-(1,3-oxazol-4-yl)phenyl]-3-methylimidazol-4-one;2-amino-5-[6-(difluoromethyl)-2-pyridinyl]-5-(3,4-difluoro-5-phenylphenyl)-3-methylimidazol-4-one;2-amino-5-[6-(difluoromethyl)-2-pyridinyl]-5-(3,4-difluoro-5-pyrazin-2-ylphenyl)-3-methylimidazol-4-one;2-amino-5-[6-(difluoromethyl)-2-pyridinyl]-5-(3,4-difluoro-5-pyridazin-3-ylphenyl)-3-methylimidazol-4-one;2-amino-5-[6-(difluoromethyl)-2-pyridinyl]-5-(3,4-difluoro-5-pyridazin-4-ylphenyl)-3-methylimidazol-4-one;2-amino-5-[6-(difluoromethyl)-2-pyridinyl]-5-(3,4-difluoro-5-pyridin-2-ylphenyl)-3-methylimidazol-4-one;2-amino-5-[6-(difluoromethyl)-2-pyridinyl]-5-[3,4-difluoro-5-(1,3-thiazol-4-yl)phenyl]-3-methylimidazol-4-one;3-[5-[2-amino-4-[6-(difluoromethyl)-2-pyridinyl]-1-methyl-5-oxoimidazol-4-yl]-2,3-difluorophenyl]benzonitrile;5-[5-[2-amino-4-[6-(difluoromethyl)-2-pyridinyl]-1-methyl-5-oxoimidazol-4-yl]-2,3-difluorophenyl]pyridine-3-carbonitrile?
The IUPAC name of 2-amino-5-[3,4-difluoro-5-(2-fluorophenyl)phenyl]-5-[6-(difluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3,4-difluoro-5-(4-fluorophenyl)phenyl]-5-[6-(difluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3,4-difluoro-5-(2-fluoropyrimidin-5-yl)phenyl]-5-[6-(difluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[6-(difluoromethyl)-2-pyridinyl]-5-[3,4-difluoro-5-(1,3-oxazol-4-yl)phenyl]-3-methylimidazol-4-one;2-amino-5-[6-(difluoromethyl)-2-pyridinyl]-5-(3,4-difluoro-5-phenylphenyl)-3-methylimidazol-4-one;2-amino-5-[6-(difluoromethyl)-2-pyridinyl]-5-(3,4-difluoro-5-pyrazin-2-ylphenyl)-3-methylimidazol-4-one;2-amino-5-[6-(difluoromethyl)-2-pyridinyl]-5-(3,4-difluoro-5-pyridazin-3-ylphenyl)-3-methylimidazol-4-one;2-amino-5-[6-(difluoromethyl)-2-pyridinyl]-5-(3,4-difluoro-5-pyridazin-4-ylphenyl)-3-methylimidazol-4-one;2-amino-5-[6-(difluoromethyl)-2-pyridinyl]-5-(3,4-difluoro-5-pyridin-2-ylphenyl)-3-methylimidazol-4-one;2-amino-5-[6-(difluoromethyl)-2-pyridinyl]-5-[3,4-difluoro-5-(1,3-thiazol-4-yl)phenyl]-3-methylimidazol-4-one;3-[5-[2-amino-4-[6-(difluoromethyl)-2-pyridinyl]-1-methyl-5-oxoimidazol-4-yl]-2,3-difluorophenyl]benzonitrile;5-[5-[2-amino-4-[6-(difluoromethyl)-2-pyridinyl]-1-methyl-5-oxoimidazol-4-yl]-2,3-difluorophenyl]pyridine-3-carbonitrile (CID 157336290) is 2-amino-5-[3,4-difluoro-5-(2-fluorophenyl)phenyl]-5-[6-(difluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3,4-difluoro-5-(4-fluorophenyl)phenyl]-5-[6-(difluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3,4-difluoro-5-(2-fluoropyrimidin-5-yl)phenyl]-5-[6-(difluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[6-(difluoromethyl)-2-pyridinyl]-5-[3,4-difluoro-5-(1,3-oxazol-4-yl)phenyl]-3-methylimidazol-4-one;2-amino-5-[6-(difluoromethyl)-2-pyridinyl]-5-(3,4-difluoro-5-phenylphenyl)-3-methylimidazol-4-one;2-amino-5-[6-(difluoromethyl)-2-pyridinyl]-5-(3,4-difluoro-5-pyrazin-2-ylphenyl)-3-methylimidazol-4-one;2-amino-5-[6-(difluoromethyl)-2-pyridinyl]-5-(3,4-difluoro-5-pyridazin-3-ylphenyl)-3-methylimidazol-4-one;2-amino-5-[6-(difluoromethyl)-2-pyridinyl]-5-(3,4-difluoro-5-pyridazin-4-ylphenyl)-3-methylimidazol-4-one;2-amino-5-[6-(difluoromethyl)-2-pyridinyl]-5-(3,4-difluoro-5-pyridin-2-ylphenyl)-3-methylimidazol-4-one;2-amino-5-[6-(difluoromethyl)-2-pyridinyl]-5-[3,4-difluoro-5-(1,3-thiazol-4-yl)phenyl]-3-methylimidazol-4-one;3-[5-[2-amino-4-[6-(difluoromethyl)-2-pyridinyl]-1-methyl-5-oxoimidazol-4-yl]-2,3-difluorophenyl]benzonitrile;5-[5-[2-amino-4-[6-(difluoromethyl)-2-pyridinyl]-1-methyl-5-oxoimidazol-4-yl]-2,3-difluorophenyl]pyridine-3-carbonitrile.
What is the SMILES notation for 2-amino-5-[3,4-difluoro-5-(2-fluorophenyl)phenyl]-5-[6-(difluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3,4-difluoro-5-(4-fluorophenyl)phenyl]-5-[6-(difluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3,4-difluoro-5-(2-fluoropyrimidin-5-yl)phenyl]-5-[6-(difluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[6-(difluoromethyl)-2-pyridinyl]-5-[3,4-difluoro-5-(1,3-oxazol-4-yl)phenyl]-3-methylimidazol-4-one;2-amino-5-[6-(difluoromethyl)-2-pyridinyl]-5-(3,4-difluoro-5-phenylphenyl)-3-methylimidazol-4-one;2-amino-5-[6-(difluoromethyl)-2-pyridinyl]-5-(3,4-difluoro-5-pyrazin-2-ylphenyl)-3-methylimidazol-4-one;2-amino-5-[6-(difluoromethyl)-2-pyridinyl]-5-(3,4-difluoro-5-pyridazin-3-ylphenyl)-3-methylimidazol-4-one;2-amino-5-[6-(difluoromethyl)-2-pyridinyl]-5-(3,4-difluoro-5-pyridazin-4-ylphenyl)-3-methylimidazol-4-one;2-amino-5-[6-(difluoromethyl)-2-pyridinyl]-5-(3,4-difluoro-5-pyridin-2-ylphenyl)-3-methylimidazol-4-one;2-amino-5-[6-(difluoromethyl)-2-pyridinyl]-5-[3,4-difluoro-5-(1,3-thiazol-4-yl)phenyl]-3-methylimidazol-4-one;3-[5-[2-amino-4-[6-(difluoromethyl)-2-pyridinyl]-1-methyl-5-oxoimidazol-4-yl]-2,3-difluorophenyl]benzonitrile;5-[5-[2-amino-4-[6-(difluoromethyl)-2-pyridinyl]-1-methyl-5-oxoimidazol-4-yl]-2,3-difluorophenyl]pyridine-3-carbonitrile?
The canonical SMILES for 2-amino-5-[3,4-difluoro-5-(2-fluorophenyl)phenyl]-5-[6-(difluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3,4-difluoro-5-(4-fluorophenyl)phenyl]-5-[6-(difluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3,4-difluoro-5-(2-fluoropyrimidin-5-yl)phenyl]-5-[6-(difluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[6-(difluoromethyl)-2-pyridinyl]-5-[3,4-difluoro-5-(1,3-oxazol-4-yl)phenyl]-3-methylimidazol-4-one;2-amino-5-[6-(difluoromethyl)-2-pyridinyl]-5-(3,4-difluoro-5-phenylphenyl)-3-methylimidazol-4-one;2-amino-5-[6-(difluoromethyl)-2-pyridinyl]-5-(3,4-difluoro-5-pyrazin-2-ylphenyl)-3-methylimidazol-4-one;2-amino-5-[6-(difluoromethyl)-2-pyridinyl]-5-(3,4-difluoro-5-pyridazin-3-ylphenyl)-3-methylimidazol-4-one;2-amino-5-[6-(difluoromethyl)-2-pyridinyl]-5-(3,4-difluoro-5-pyridazin-4-ylphenyl)-3-methylimidazol-4-one;2-amino-5-[6-(difluoromethyl)-2-pyridinyl]-5-(3,4-difluoro-5-pyridin-2-ylphenyl)-3-methylimidazol-4-one;2-amino-5-[6-(difluoromethyl)-2-pyridinyl]-5-[3,4-difluoro-5-(1,3-thiazol-4-yl)phenyl]-3-methylimidazol-4-one;3-[5-[2-amino-4-[6-(difluoromethyl)-2-pyridinyl]-1-methyl-5-oxoimidazol-4-yl]-2,3-difluorophenyl]benzonitrile;5-[5-[2-amino-4-[6-(difluoromethyl)-2-pyridinyl]-1-methyl-5-oxoimidazol-4-yl]-2,3-difluorophenyl]pyridine-3-carbonitrile is CN1C(=O)C(c2cc(F)c(F)c(-c3ccc(F)cc3)c2)(c2cccc(C(F)F)n2)N=C1N.CN1C(=O)C(c2cc(F)c(F)c(-c3cccc(C#N)c3)c2)(c2cccc(C(F)F)n2)N=C1N.CN1C(=O)C(c2cc(F)c(F)c(-c3ccccc3)c2)(c2cccc(C(F)F)n2)N=C1N.CN1C(=O)C(c2cc(F)c(F)c(-c3ccccc3F)c2)(c2cccc(C(F)F)n2)N=C1N.CN1C(=O)C(c2cc(F)c(F)c(-c3ccccn3)c2)(c2cccc(C(F)F)n2)N=C1N.CN1C(=O)C(c2cc(F)c(F)c(-c3cccnn3)c2)(c2cccc(C(F)F)n2)N=C1N.CN1C(=O)C(c2cc(F)c(F)c(-c3ccnnc3)c2)(c2cccc(C(F)F)n2)N=C1N.CN1C(=O)C(c2cc(F)c(F)c(-c3cnc(F)nc3)c2)(c2cccc(C(F)F)n2)N=C1N.CN1C(=O)C(c2cc(F)c(F)c(-c3cncc(C#N)c3)c2)(c2cccc(C(F)F)n2)N=C1N.CN1C(=O)C(c2cc(F)c(F)c(-c3cnccn3)c2)(c2cccc(C(F)F)n2)N=C1N.CN1C(=O)C(c2cc(F)c(F)c(-c3cocn3)c2)(c2cccc(C(F)F)n2)N=C1N.CN1C(=O)C(c2cc(F)c(F)c(-c3cscn3)c2)(c2cccc(C(F)F)n2)N=C1N.
What is the InChIKey of 2-amino-5-[3,4-difluoro-5-(2-fluorophenyl)phenyl]-5-[6-(difluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3,4-difluoro-5-(4-fluorophenyl)phenyl]-5-[6-(difluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3,4-difluoro-5-(2-fluoropyrimidin-5-yl)phenyl]-5-[6-(difluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[6-(difluoromethyl)-2-pyridinyl]-5-[3,4-difluoro-5-(1,3-oxazol-4-yl)phenyl]-3-methylimidazol-4-one;2-amino-5-[6-(difluoromethyl)-2-pyridinyl]-5-(3,4-difluoro-5-phenylphenyl)-3-methylimidazol-4-one;2-amino-5-[6-(difluoromethyl)-2-pyridinyl]-5-(3,4-difluoro-5-pyrazin-2-ylphenyl)-3-methylimidazol-4-one;2-amino-5-[6-(difluoromethyl)-2-pyridinyl]-5-(3,4-difluoro-5-pyridazin-3-ylphenyl)-3-methylimidazol-4-one;2-amino-5-[6-(difluoromethyl)-2-pyridinyl]-5-(3,4-difluoro-5-pyridazin-4-ylphenyl)-3-methylimidazol-4-one;2-amino-5-[6-(difluoromethyl)-2-pyridinyl]-5-(3,4-difluoro-5-pyridin-2-ylphenyl)-3-methylimidazol-4-one;2-amino-5-[6-(difluoromethyl)-2-pyridinyl]-5-[3,4-difluoro-5-(1,3-thiazol-4-yl)phenyl]-3-methylimidazol-4-one;3-[5-[2-amino-4-[6-(difluoromethyl)-2-pyridinyl]-1-methyl-5-oxoimidazol-4-yl]-2,3-difluorophenyl]benzonitrile;5-[5-[2-amino-4-[6-(difluoromethyl)-2-pyridinyl]-1-methyl-5-oxoimidazol-4-yl]-2,3-difluorophenyl]pyridine-3-carbonitrile?
The InChIKey is BFWKOFDSVCDLAI-UHFFFAOYSA-N. The full InChI is InChI=1S/C23H15F4N5O.2C22H15F5N4O.C22H14F4N6O.C22H16F4N4O.C21H15F4N5O.C20H13F5N6O.3C20H14F4N6O.C19H13F4N5O2.C19H13F4N5OS/c1-32-21(33)23(31-22(32)29,18-7-3-6-17(30-18)20(26)27)14-9-15(19(25)16(24)10-14)13-5-2-4-12(8-13)11-28;1-31-20(32)22(30-21(31)28,17-8-4-7-16(29-17)19(26)27)11-9-13(18(25)15(24)10-11)12-5-2-3-6-14(12)23;1-31-20(32)22(30-21(31)28,17-4-2-3-16(29-17)19(26)27)12-9-14(18(25)15(24)10-12)11-5-7-13(23)8-6-11;1-32-20(33)22(31-21(32)28,17-4-2-3-16(30-17)19(25)26)13-6-14(18(24)15(23)7-13)12-5-11(8-27)9-29-10-12;1-30-20(31)22(29-21(30)27,17-9-5-8-16(28-17)19(25)26)13-10-14(18(24)15(23)11-13)12-6-3-2-4-7-12;1-30-19(31)21(29-20(30)26,16-7-4-6-15(28-16)18(24)25)11-9-12(17(23)13(22)10-11)14-5-2-3-8-27-14;1-31-17(32)20(30-19(31)26,14-4-2-3-13(29-14)16(23)24)10-5-11(15(22)12(21)6-10)9-7-27-18(25)28-8-9;1-30-18(31)20(28-19(30)25,15-6-2-4-14(27-15)17(23)24)10-8-11(16(22)12(21)9-10)13-5-3-7-26-29-13;1-30-18(31)20(29-19(30)25,15-4-2-3-13(28-15)17(23)24)10-7-11(16(22)12(21)8-10)14-9-26-5-6-27-14;1-30-18(31)20(29-19(30)25,15-4-2-3-14(28-15)17(23)24)11-7-12(16(22)13(21)8-11)10-5-6-26-27-9-10;2*1-28-17(29)19(27-18(28)24,14-4-2-3-12(26-14)16(22)23)9-5-10(13-7-30-8-25-13)15(21)11(20)6-9/h2-10,20H,1H3,(H2,29,31);2*2-10,19H,1H3,(H2,28,30);2-7,9-10,19H,1H3,(H2,28,31);2-11,19H,1H3,(H2,27,29);2-10,18H,1H3,(H2,26,29);2-8,16H,1H3,(H2,26,30);2-9,17H,1H3,(H2,25,28);2*2-9,17H,1H3,(H2,25,29);2*2-8,16H,1H3,(H2,24,27).
What are the key properties of 2-amino-5-[3,4-difluoro-5-(2-fluorophenyl)phenyl]-5-[6-(difluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3,4-difluoro-5-(4-fluorophenyl)phenyl]-5-[6-(difluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3,4-difluoro-5-(2-fluoropyrimidin-5-yl)phenyl]-5-[6-(difluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[6-(difluoromethyl)-2-pyridinyl]-5-[3,4-difluoro-5-(1,3-oxazol-4-yl)phenyl]-3-methylimidazol-4-one;2-amino-5-[6-(difluoromethyl)-2-pyridinyl]-5-(3,4-difluoro-5-phenylphenyl)-3-methylimidazol-4-one;2-amino-5-[6-(difluoromethyl)-2-pyridinyl]-5-(3,4-difluoro-5-pyrazin-2-ylphenyl)-3-methylimidazol-4-one;2-amino-5-[6-(difluoromethyl)-2-pyridinyl]-5-(3,4-difluoro-5-pyridazin-3-ylphenyl)-3-methylimidazol-4-one;2-amino-5-[6-(difluoromethyl)-2-pyridinyl]-5-(3,4-difluoro-5-pyridazin-4-ylphenyl)-3-methylimidazol-4-one;2-amino-5-[6-(difluoromethyl)-2-pyridinyl]-5-(3,4-difluoro-5-pyridin-2-ylphenyl)-3-methylimidazol-4-one;2-amino-5-[6-(difluoromethyl)-2-pyridinyl]-5-[3,4-difluoro-5-(1,3-thiazol-4-yl)phenyl]-3-methylimidazol-4-one;3-[5-[2-amino-4-[6-(difluoromethyl)-2-pyridinyl]-1-methyl-5-oxoimidazol-4-yl]-2,3-difluorophenyl]benzonitrile;5-[5-[2-amino-4-[6-(difluoromethyl)-2-pyridinyl]-1-methyl-5-oxoimidazol-4-yl]-2,3-difluorophenyl]pyridine-3-carbonitrile?
2-amino-5-[3,4-difluoro-5-(2-fluorophenyl)phenyl]-5-[6-(difluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3,4-difluoro-5-(4-fluorophenyl)phenyl]-5-[6-(difluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3,4-difluoro-5-(2-fluoropyrimidin-5-yl)phenyl]-5-[6-(difluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[6-(difluoromethyl)-2-pyridinyl]-5-[3,4-difluoro-5-(1,3-oxazol-4-yl)phenyl]-3-methylimidazol-4-one;2-amino-5-[6-(difluoromethyl)-2-pyridinyl]-5-(3,4-difluoro-5-phenylphenyl)-3-methylimidazol-4-one;2-amino-5-[6-(difluoromethyl)-2-pyridinyl]-5-(3,4-difluoro-5-pyrazin-2-ylphenyl)-3-methylimidazol-4-one;2-amino-5-[6-(difluoromethyl)-2-pyridinyl]-5-(3,4-difluoro-5-pyridazin-3-ylphenyl)-3-methylimidazol-4-one;2-amino-5-[6-(difluoromethyl)-2-pyridinyl]-5-(3,4-difluoro-5-pyridazin-4-ylphenyl)-3-methylimidazol-4-one;2-amino-5-[6-(difluoromethyl)-2-pyridinyl]-5-(3,4-difluoro-5-pyridin-2-ylphenyl)-3-methylimidazol-4-one;2-amino-5-[6-(difluoromethyl)-2-pyridinyl]-5-[3,4-difluoro-5-(1,3-thiazol-4-yl)phenyl]-3-methylimidazol-4-one;3-[5-[2-amino-4-[6-(difluoromethyl)-2-pyridinyl]-1-methyl-5-oxoimidazol-4-yl]-2,3-difluorophenyl]benzonitrile;5-[5-[2-amino-4-[6-(difluoromethyl)-2-pyridinyl]-1-methyl-5-oxoimidazol-4-yl]-2,3-difluorophenyl]pyridine-3-carbonitrile has a molecular weight of 5252.50 g/mol, XLogP of 40.49, 48 rotatable bonds, 12 hydrogen bond donors, and 64 hydrogen bond acceptors.
Where does this data come from?
All data for 2-amino-5-[3,4-difluoro-5-(2-fluorophenyl)phenyl]-5-[6-(difluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3,4-difluoro-5-(4-fluorophenyl)phenyl]-5-[6-(difluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3,4-difluoro-5-(2-fluoropyrimidin-5-yl)phenyl]-5-[6-(difluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[6-(difluoromethyl)-2-pyridinyl]-5-[3,4-difluoro-5-(1,3-oxazol-4-yl)phenyl]-3-methylimidazol-4-one;2-amino-5-[6-(difluoromethyl)-2-pyridinyl]-5-(3,4-difluoro-5-phenylphenyl)-3-methylimidazol-4-one;2-amino-5-[6-(difluoromethyl)-2-pyridinyl]-5-(3,4-difluoro-5-pyrazin-2-ylphenyl)-3-methylimidazol-4-one;2-amino-5-[6-(difluoromethyl)-2-pyridinyl]-5-(3,4-difluoro-5-pyridazin-3-ylphenyl)-3-methylimidazol-4-one;2-amino-5-[6-(difluoromethyl)-2-pyridinyl]-5-(3,4-difluoro-5-pyridazin-4-ylphenyl)-3-methylimidazol-4-one;2-amino-5-[6-(difluoromethyl)-2-pyridinyl]-5-(3,4-difluoro-5-pyridin-2-ylphenyl)-3-methylimidazol-4-one;2-amino-5-[6-(difluoromethyl)-2-pyridinyl]-5-[3,4-difluoro-5-(1,3-thiazol-4-yl)phenyl]-3-methylimidazol-4-one;3-[5-[2-amino-4-[6-(difluoromethyl)-2-pyridinyl]-1-methyl-5-oxoimidazol-4-yl]-2,3-difluorophenyl]benzonitrile;5-[5-[2-amino-4-[6-(difluoromethyl)-2-pyridinyl]-1-methyl-5-oxoimidazol-4-yl]-2,3-difluorophenyl]pyridine-3-carbonitrile is sourced from PubChem (CID 157336290), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).