3-hydroxy-7-(5-methylfuran-2-yl)-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one;7-(5-methylfuran-2-yl)-2-oxo-6-quinolin-6-yl-1H-1,8-naphthyridine-3-carboxamide;7-(2-methyl-1,3-thiazol-5-yl)-2-oxo-6-quinolin-6-yl-1H-1,8-naphthyridine-3-carbonitrile;7-(2-methyl-1,3-thiazol-5-yl)-2-oxo-6-quinolin-6-yl-1H-1,8-naphthyridine-3-carboxamide;7-(5-methylthiophen-2-yl)-2-oxo-6-quinolin-6-yl-1H-1,8-naphthyridine-3-carbonitrile;7-(5-methylthiophen-2-yl)-2-oxo-6-quinolin-6-yl-1H-1,8-naphthyridine-3-carboxamide

C135H89N25O12S4 — CID 157339930

About 3-hydroxy-7-(5-methylfuran-2-yl)-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one;7-(5-methylfuran-2-yl)-2-oxo-6-quinolin-6-yl-1H-1,8-naphthyridine-3-carboxamide;7-(2-methyl-1,3-thiazol-5-yl)-2-oxo-6-quinolin-6-yl-1H-1,8-naphthyridine-3-carbonitrile;7-(2-methyl-1,3-thiazol-5-yl)-2-oxo-6-quinolin-6-yl-1H-1,8-naphthyridine-3-carboxamide;7-(5-methylthiophen-2-yl)-2-oxo-6-quinolin-6-yl-1H-1,8-naphthyridine-3-carbonitrile;7-(5-methylthiophen-2-yl)-2-oxo-6-quinolin-6-yl-1H-1,8-naphthyridine-3-carboxamide

3-hydroxy-7-(5-methylfuran-2-yl)-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one;7-(5-methylfuran-2-yl)-2-oxo-6-quinolin-6-yl-1H-1,8-naphthyridine-3-carboxamide;7-(2-methyl-1,3-thiazol-5-yl)-2-oxo-6-quinolin-6-yl-1H-1,8-naphthyridine-3-carbonitrile;7-(2-methyl-1,3-thiazol-5-yl)-2-oxo-6-quinolin-6-yl-1H-1,8-naphthyridine-3-carboxamide;7-(5-methylthiophen-2-yl)-2-oxo-6-quinolin-6-yl-1H-1,8-naphthyridine-3-carbonitrile;7-(5-methylthiophen-2-yl)-2-oxo-6-quinolin-6-yl-1H-1,8-naphthyridine-3-carboxamide (PubChem CID 157339930) has the molecular formula C135H89N25O12S4 and a molecular weight of 2381.63 g/mol. Its IUPAC name is 3-hydroxy-7-(5-methylfuran-2-yl)-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one;7-(5-methylfuran-2-yl)-2-oxo-6-quinolin-6-yl-1H-1,8-naphthyridine-3-carboxamide;7-(2-methyl-1,3-thiazol-5-yl)-2-oxo-6-quinolin-6-yl-1H-1,8-naphthyridine-3-carbonitrile;7-(2-methyl-1,3-thiazol-5-yl)-2-oxo-6-quinolin-6-yl-1H-1,8-naphthyridine-3-carboxamide;7-(5-methylthiophen-2-yl)-2-oxo-6-quinolin-6-yl-1H-1,8-naphthyridine-3-carbonitrile;7-(5-methylthiophen-2-yl)-2-oxo-6-quinolin-6-yl-1H-1,8-naphthyridine-3-carboxamide.

Molecular Properties

• Compound Name: 3-hydroxy-7-(5-methylfuran-2-yl)-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one;7-(5-methylfuran-2-yl)-2-oxo-6-quinolin-6-yl-1H-1,8-naphthyridine-3-carboxamide;7-(2-methyl-1,3-thiazol-5-yl)-2-oxo-6-quinolin-6-yl-1H-1,8-naphthyridine-3-carbonitrile;7-(2-methyl-1,3-thiazol-5-yl)-2-oxo-6-quinolin-6-yl-1H-1,8-naphthyridine-3-carboxamide;7-(5-methylthiophen-2-yl)-2-oxo-6-quinolin-6-yl-1H-1,8-naphthyridine-3-carbonitrile;7-(5-methylthiophen-2-yl)-2-oxo-6-quinolin-6-yl-1H-1,8-naphthyridine-3-carboxamide
• PubChem CID: 157339930
• Molecular Formula: C135H89N25O12S4
• Molecular Weight: 2381.63 g/mol
• Exact Mass: 2379.60
• IUPAC Name: 3-hydroxy-7-(5-methylfuran-2-yl)-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one;7-(5-methylfuran-2-yl)-2-oxo-6-quinolin-6-yl-1H-1,8-naphthyridine-3-carboxamide;7-(2-methyl-1,3-thiazol-5-yl)-2-oxo-6-quinolin-6-yl-1H-1,8-naphthyridine-3-carbonitrile;7-(2-methyl-1,3-thiazol-5-yl)-2-oxo-6-quinolin-6-yl-1H-1,8-naphthyridine-3-carboxamide;7-(5-methylthiophen-2-yl)-2-oxo-6-quinolin-6-yl-1H-1,8-naphthyridine-3-carbonitrile;7-(5-methylthiophen-2-yl)-2-oxo-6-quinolin-6-yl-1H-1,8-naphthyridine-3-carboxamide
• SMILES: Cc1ccc(-c2nc3[nH]c(=O)c(C#N)cc3cc2-c2ccc3ncccc3c2)s1.Cc1ccc(-c2nc3[nH]c(=O)c(C(N)=O)cc3cc2-c2ccc3ncccc3c2)o1.Cc1ccc(-c2nc3[nH]c(=O)c(C(N)=O)cc3cc2-c2ccc3ncccc3c2)s1.Cc1ccc(-c2nc3[nH]c(=O)c(O)cc3cc2-c2ccc3ncccc3c2)o1.Cc1ncc(-c2nc3[nH]c(=O)c(C#N)cc3cc2-c2ccc3ncccc3c2)s1.Cc1ncc(-c2nc3[nH]c(=O)c(C(N)=O)cc3cc2-c2ccc3ncccc3c2)s1
• InChI: InChI=1S/C23H16N4O3.C23H16N4O2S.C23H14N4OS.C22H15N5O2S.C22H13N5OS.C22H15N3O3/c2*1-12-4-7-19(30-12)20-16(13-5-6-18-14(9-13)3-2-8-25-18)10-15-11-17(21(24)28)23(29)27-22(15)26-20;1-13-4-7-20(29-13)21-18(14-5-6-19-15(9-14)3-2-8-25-19)11-16-10-17(12-24)23(28)27-22(16)26-21;1-11-25-10-18(30-11)19-15(12-4-5-17-13(7-12)3-2-6-24-17)8-14-9-16(20(23)28)22(29)27-21(14)26-19;1-12-25-11-19(29-12)20-17(13-4-5-18-14(7-13)3-2-6-24-18)9-15-8-16(10-23)22(28)27-21(15)26-20;1-12-4-7-19(28-12)20-16(10-15-11-18(26)22(27)25-21(15)24-20)13-5-6-17-14(9-13)3-2-8-23-17/h2*2-11H,1H3,(H2,24,28)(H,26,27,29);2-11H,1H3,(H,26,27,28);2-10H,1H3,(H2,23,28)(H,26,27,29);2-9,11H,1H3,(H,26,27,28);2-11,26H,1H3,(H,24,25,27)
• InChIKey: BGGXJFVJZYKQRE-UHFFFAOYSA-N
• XLogP: 25.65
• TPSA: 600.98 Ų
• H-Bond Donors: 10
• H-Bond Acceptors: 32
• Rotatable Bonds: 15
• Heavy Atoms: 176
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2381.63
LogP ≤ 5	25.65
H-Bond Donors ≤ 5	10
H-Bond Acceptors ≤ 10	32

Frequently Asked Questions

What is the IUPAC name of 3-hydroxy-7-(5-methylfuran-2-yl)-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one;7-(5-methylfuran-2-yl)-2-oxo-6-quinolin-6-yl-1H-1,8-naphthyridine-3-carboxamide;7-(2-methyl-1,3-thiazol-5-yl)-2-oxo-6-quinolin-6-yl-1H-1,8-naphthyridine-3-carbonitrile;7-(2-methyl-1,3-thiazol-5-yl)-2-oxo-6-quinolin-6-yl-1H-1,8-naphthyridine-3-carboxamide;7-(5-methylthiophen-2-yl)-2-oxo-6-quinolin-6-yl-1H-1,8-naphthyridine-3-carbonitrile;7-(5-methylthiophen-2-yl)-2-oxo-6-quinolin-6-yl-1H-1,8-naphthyridine-3-carboxamide?

The IUPAC name of 3-hydroxy-7-(5-methylfuran-2-yl)-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one;7-(5-methylfuran-2-yl)-2-oxo-6-quinolin-6-yl-1H-1,8-naphthyridine-3-carboxamide;7-(2-methyl-1,3-thiazol-5-yl)-2-oxo-6-quinolin-6-yl-1H-1,8-naphthyridine-3-carbonitrile;7-(2-methyl-1,3-thiazol-5-yl)-2-oxo-6-quinolin-6-yl-1H-1,8-naphthyridine-3-carboxamide;7-(5-methylthiophen-2-yl)-2-oxo-6-quinolin-6-yl-1H-1,8-naphthyridine-3-carbonitrile;7-(5-methylthiophen-2-yl)-2-oxo-6-quinolin-6-yl-1H-1,8-naphthyridine-3-carboxamide (CID 157339930) is 3-hydroxy-7-(5-methylfuran-2-yl)-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one;7-(5-methylfuran-2-yl)-2-oxo-6-quinolin-6-yl-1H-1,8-naphthyridine-3-carboxamide;7-(2-methyl-1,3-thiazol-5-yl)-2-oxo-6-quinolin-6-yl-1H-1,8-naphthyridine-3-carbonitrile;7-(2-methyl-1,3-thiazol-5-yl)-2-oxo-6-quinolin-6-yl-1H-1,8-naphthyridine-3-carboxamide;7-(5-methylthiophen-2-yl)-2-oxo-6-quinolin-6-yl-1H-1,8-naphthyridine-3-carbonitrile;7-(5-methylthiophen-2-yl)-2-oxo-6-quinolin-6-yl-1H-1,8-naphthyridine-3-carboxamide.

What is the SMILES notation for 3-hydroxy-7-(5-methylfuran-2-yl)-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one;7-(5-methylfuran-2-yl)-2-oxo-6-quinolin-6-yl-1H-1,8-naphthyridine-3-carboxamide;7-(2-methyl-1,3-thiazol-5-yl)-2-oxo-6-quinolin-6-yl-1H-1,8-naphthyridine-3-carbonitrile;7-(2-methyl-1,3-thiazol-5-yl)-2-oxo-6-quinolin-6-yl-1H-1,8-naphthyridine-3-carboxamide;7-(5-methylthiophen-2-yl)-2-oxo-6-quinolin-6-yl-1H-1,8-naphthyridine-3-carbonitrile;7-(5-methylthiophen-2-yl)-2-oxo-6-quinolin-6-yl-1H-1,8-naphthyridine-3-carboxamide?

The canonical SMILES for 3-hydroxy-7-(5-methylfuran-2-yl)-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one;7-(5-methylfuran-2-yl)-2-oxo-6-quinolin-6-yl-1H-1,8-naphthyridine-3-carboxamide;7-(2-methyl-1,3-thiazol-5-yl)-2-oxo-6-quinolin-6-yl-1H-1,8-naphthyridine-3-carbonitrile;7-(2-methyl-1,3-thiazol-5-yl)-2-oxo-6-quinolin-6-yl-1H-1,8-naphthyridine-3-carboxamide;7-(5-methylthiophen-2-yl)-2-oxo-6-quinolin-6-yl-1H-1,8-naphthyridine-3-carbonitrile;7-(5-methylthiophen-2-yl)-2-oxo-6-quinolin-6-yl-1H-1,8-naphthyridine-3-carboxamide is Cc1ccc(-c2nc3[nH]c(=O)c(C#N)cc3cc2-c2ccc3ncccc3c2)s1.Cc1ccc(-c2nc3[nH]c(=O)c(C(N)=O)cc3cc2-c2ccc3ncccc3c2)o1.Cc1ccc(-c2nc3[nH]c(=O)c(C(N)=O)cc3cc2-c2ccc3ncccc3c2)s1.Cc1ccc(-c2nc3[nH]c(=O)c(O)cc3cc2-c2ccc3ncccc3c2)o1.Cc1ncc(-c2nc3[nH]c(=O)c(C#N)cc3cc2-c2ccc3ncccc3c2)s1.Cc1ncc(-c2nc3[nH]c(=O)c(C(N)=O)cc3cc2-c2ccc3ncccc3c2)s1.

What is the InChIKey of 3-hydroxy-7-(5-methylfuran-2-yl)-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one;7-(5-methylfuran-2-yl)-2-oxo-6-quinolin-6-yl-1H-1,8-naphthyridine-3-carboxamide;7-(2-methyl-1,3-thiazol-5-yl)-2-oxo-6-quinolin-6-yl-1H-1,8-naphthyridine-3-carbonitrile;7-(2-methyl-1,3-thiazol-5-yl)-2-oxo-6-quinolin-6-yl-1H-1,8-naphthyridine-3-carboxamide;7-(5-methylthiophen-2-yl)-2-oxo-6-quinolin-6-yl-1H-1,8-naphthyridine-3-carbonitrile;7-(5-methylthiophen-2-yl)-2-oxo-6-quinolin-6-yl-1H-1,8-naphthyridine-3-carboxamide?

The InChIKey is BGGXJFVJZYKQRE-UHFFFAOYSA-N. The full InChI is InChI=1S/C23H16N4O3.C23H16N4O2S.C23H14N4OS.C22H15N5O2S.C22H13N5OS.C22H15N3O3/c2*1-12-4-7-19(30-12)20-16(13-5-6-18-14(9-13)3-2-8-25-18)10-15-11-17(21(24)28)23(29)27-22(15)26-20;1-13-4-7-20(29-13)21-18(14-5-6-19-15(9-14)3-2-8-25-19)11-16-10-17(12-24)23(28)27-22(16)26-21;1-11-25-10-18(30-11)19-15(12-4-5-17-13(7-12)3-2-6-24-17)8-14-9-16(20(23)28)22(29)27-21(14)26-19;1-12-25-11-19(29-12)20-17(13-4-5-18-14(7-13)3-2-6-24-18)9-15-8-16(10-23)22(28)27-21(15)26-20;1-12-4-7-19(28-12)20-16(10-15-11-18(26)22(27)25-21(15)24-20)13-5-6-17-14(9-13)3-2-8-23-17/h2*2-11H,1H3,(H2,24,28)(H,26,27,29);2-11H,1H3,(H,26,27,28);2-10H,1H3,(H2,23,28)(H,26,27,29);2-9,11H,1H3,(H,26,27,28);2-11,26H,1H3,(H,24,25,27).

What are the key properties of 3-hydroxy-7-(5-methylfuran-2-yl)-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one;7-(5-methylfuran-2-yl)-2-oxo-6-quinolin-6-yl-1H-1,8-naphthyridine-3-carboxamide;7-(2-methyl-1,3-thiazol-5-yl)-2-oxo-6-quinolin-6-yl-1H-1,8-naphthyridine-3-carbonitrile;7-(2-methyl-1,3-thiazol-5-yl)-2-oxo-6-quinolin-6-yl-1H-1,8-naphthyridine-3-carboxamide;7-(5-methylthiophen-2-yl)-2-oxo-6-quinolin-6-yl-1H-1,8-naphthyridine-3-carbonitrile;7-(5-methylthiophen-2-yl)-2-oxo-6-quinolin-6-yl-1H-1,8-naphthyridine-3-carboxamide?

3-hydroxy-7-(5-methylfuran-2-yl)-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one;7-(5-methylfuran-2-yl)-2-oxo-6-quinolin-6-yl-1H-1,8-naphthyridine-3-carboxamide;7-(2-methyl-1,3-thiazol-5-yl)-2-oxo-6-quinolin-6-yl-1H-1,8-naphthyridine-3-carbonitrile;7-(2-methyl-1,3-thiazol-5-yl)-2-oxo-6-quinolin-6-yl-1H-1,8-naphthyridine-3-carboxamide;7-(5-methylthiophen-2-yl)-2-oxo-6-quinolin-6-yl-1H-1,8-naphthyridine-3-carbonitrile;7-(5-methylthiophen-2-yl)-2-oxo-6-quinolin-6-yl-1H-1,8-naphthyridine-3-carboxamide has a molecular weight of 2381.63 g/mol, XLogP of 25.65, 15 rotatable bonds, 10 hydrogen bond donors, and 32 hydrogen bond acceptors.

Where does this data come from?

All data for 3-hydroxy-7-(5-methylfuran-2-yl)-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one;7-(5-methylfuran-2-yl)-2-oxo-6-quinolin-6-yl-1H-1,8-naphthyridine-3-carboxamide;7-(2-methyl-1,3-thiazol-5-yl)-2-oxo-6-quinolin-6-yl-1H-1,8-naphthyridine-3-carbonitrile;7-(2-methyl-1,3-thiazol-5-yl)-2-oxo-6-quinolin-6-yl-1H-1,8-naphthyridine-3-carboxamide;7-(5-methylthiophen-2-yl)-2-oxo-6-quinolin-6-yl-1H-1,8-naphthyridine-3-carbonitrile;7-(5-methylthiophen-2-yl)-2-oxo-6-quinolin-6-yl-1H-1,8-naphthyridine-3-carboxamide is sourced from PubChem (CID 157339930), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).