(3R)-3-[(7-benzyl-1-oxo-3H-furo[3,2-e]isoindol-2-yl)methyl]-3-furo[3,2-b]pyridin-2-ylpyrrolidine-2,5-dione;(3R)-3-[(7-cyclopropyl-1-oxo-3H-furo[3,2-e]isoindol-2-yl)methyl]-3-furo[3,2-b]pyridin-2-ylpyrrolidine-2,5-dione;3-[(8-fluoro-2-methyl-7-oxo-5H-furo[2,3-f]isoindol-6-yl)methyl]-3-[5-(1H-pyrazol-4-yl)furo[3,2-b]pyridin-2-yl]pyrrolidine-2,5-dione;(3R)-3-furo[3,2-b]pyridin-2-yl-3-[[7-(methoxymethyl)-1-oxo-3H-furo[3,2-e]isoindol-2-yl]methyl]pyrrolidine-2,5-dione;(3R)-3-furo[3,2-b]pyridin-2-yl-3-[(7-methyl-1-oxo-3,6-dihydrocyclopenta[e]isoindol-2-yl)methyl]pyrrolidine-2,5-dione

C128H96FN17O25 — CID 157341836

About (3R)-3-[(7-benzyl-1-oxo-3H-furo[3,2-e]isoindol-2-yl)methyl]-3-furo[3,2-b]pyridin-2-ylpyrrolidine-2,5-dione;(3R)-3-[(7-cyclopropyl-1-oxo-3H-furo[3,2-e]isoindol-2-yl)methyl]-3-furo[3,2-b]pyridin-2-ylpyrrolidine-2,5-dione;3-[(8-fluoro-2-methyl-7-oxo-5H-furo[2,3-f]isoindol-6-yl)methyl]-3-[5-(1H-pyrazol-4-yl)furo[3,2-b]pyridin-2-yl]pyrrolidine-2,5-dione;(3R)-3-furo[3,2-b]pyridin-2-yl-3-[[7-(methoxymethyl)-1-oxo-3H-furo[3,2-e]isoindol-2-yl]methyl]pyrrolidine-2,5-dione;(3R)-3-furo[3,2-b]pyridin-2-yl-3-[(7-methyl-1-oxo-3,6-dihydrocyclopenta[e]isoindol-2-yl)methyl]pyrrolidine-2,5-dione

(3R)-3-[(7-benzyl-1-oxo-3H-furo[3,2-e]isoindol-2-yl)methyl]-3-furo[3,2-b]pyridin-2-ylpyrrolidine-2,5-dione;(3R)-3-[(7-cyclopropyl-1-oxo-3H-furo[3,2-e]isoindol-2-yl)methyl]-3-furo[3,2-b]pyridin-2-ylpyrrolidine-2,5-dione;3-[(8-fluoro-2-methyl-7-oxo-5H-furo[2,3-f]isoindol-6-yl)methyl]-3-[5-(1H-pyrazol-4-yl)furo[3,2-b]pyridin-2-yl]pyrrolidine-2,5-dione;(3R)-3-furo[3,2-b]pyridin-2-yl-3-[[7-(methoxymethyl)-1-oxo-3H-furo[3,2-e]isoindol-2-yl]methyl]pyrrolidine-2,5-dione;(3R)-3-furo[3,2-b]pyridin-2-yl-3-[(7-methyl-1-oxo-3,6-dihydrocyclopenta[e]isoindol-2-yl)methyl]pyrrolidine-2,5-dione (PubChem CID 157341836) has the molecular formula C128H96FN17O25 and a molecular weight of 2291.27 g/mol. Its IUPAC name is (3R)-3-[(7-benzyl-1-oxo-3H-furo[3,2-e]isoindol-2-yl)methyl]-3-furo[3,2-b]pyridin-2-ylpyrrolidine-2,5-dione;(3R)-3-[(7-cyclopropyl-1-oxo-3H-furo[3,2-e]isoindol-2-yl)methyl]-3-furo[3,2-b]pyridin-2-ylpyrrolidine-2,5-dione;3-[(8-fluoro-2-methyl-7-oxo-5H-furo[2,3-f]isoindol-6-yl)methyl]-3-[5-(1H-pyrazol-4-yl)furo[3,2-b]pyridin-2-yl]pyrrolidine-2,5-dione;(3R)-3-furo[3,2-b]pyridin-2-yl-3-[[7-(methoxymethyl)-1-oxo-3H-furo[3,2-e]isoindol-2-yl]methyl]pyrrolidine-2,5-dione;(3R)-3-furo[3,2-b]pyridin-2-yl-3-[(7-methyl-1-oxo-3,6-dihydrocyclopenta[e]isoindol-2-yl)methyl]pyrrolidine-2,5-dione.

Molecular Properties

• Compound Name: (3R)-3-[(7-benzyl-1-oxo-3H-furo[3,2-e]isoindol-2-yl)methyl]-3-furo[3,2-b]pyridin-2-ylpyrrolidine-2,5-dione;(3R)-3-[(7-cyclopropyl-1-oxo-3H-furo[3,2-e]isoindol-2-yl)methyl]-3-furo[3,2-b]pyridin-2-ylpyrrolidine-2,5-dione;3-[(8-fluoro-2-methyl-7-oxo-5H-furo[2,3-f]isoindol-6-yl)methyl]-3-[5-(1H-pyrazol-4-yl)furo[3,2-b]pyridin-2-yl]pyrrolidine-2,5-dione;(3R)-3-furo[3,2-b]pyridin-2-yl-3-[[7-(methoxymethyl)-1-oxo-3H-furo[3,2-e]isoindol-2-yl]methyl]pyrrolidine-2,5-dione;(3R)-3-furo[3,2-b]pyridin-2-yl-3-[(7-methyl-1-oxo-3,6-dihydrocyclopenta[e]isoindol-2-yl)methyl]pyrrolidine-2,5-dione
• PubChem CID: 157341836
• Molecular Formula: C128H96FN17O25
• Molecular Weight: 2291.27 g/mol
• Exact Mass: 2289.67
• IUPAC Name: (3R)-3-[(7-benzyl-1-oxo-3H-furo[3,2-e]isoindol-2-yl)methyl]-3-furo[3,2-b]pyridin-2-ylpyrrolidine-2,5-dione;(3R)-3-[(7-cyclopropyl-1-oxo-3H-furo[3,2-e]isoindol-2-yl)methyl]-3-furo[3,2-b]pyridin-2-ylpyrrolidine-2,5-dione;3-[(8-fluoro-2-methyl-7-oxo-5H-furo[2,3-f]isoindol-6-yl)methyl]-3-[5-(1H-pyrazol-4-yl)furo[3,2-b]pyridin-2-yl]pyrrolidine-2,5-dione;(3R)-3-furo[3,2-b]pyridin-2-yl-3-[[7-(methoxymethyl)-1-oxo-3H-furo[3,2-e]isoindol-2-yl]methyl]pyrrolidine-2,5-dione;(3R)-3-furo[3,2-b]pyridin-2-yl-3-[(7-methyl-1-oxo-3,6-dihydrocyclopenta[e]isoindol-2-yl)methyl]pyrrolidine-2,5-dione
• SMILES: CC1=Cc2c(ccc3c2C(=O)N(C[C@@]2(c4cc5ncccc5o4)CC(=O)NC2=O)C3)C1.COCc1cc2c3c(ccc2o1)CN(C[C@@]1(c2cc4ncccc4o2)CC(=O)NC1=O)C3=O.Cc1cc2cc3c(c(F)c2o1)C(=O)N(CC1(c2cc4nc(-c5cn[nH]c5)ccc4o2)CC(=O)NC1=O)C3.O=C1C[C@@](CN2Cc3ccc4oc(C5CC5)cc4c3C2=O)(c2cc3ncccc3o2)C(=O)N1.O=C1C[C@@](CN2Cc3ccc4oc(Cc5ccccc5)cc4c3C2=O)(c2cc3ncccc3o2)C(=O)N1
• InChI: InChI=1S/C29H21N3O5.C26H18FN5O5.C25H19N3O5.C24H19N3O6.C24H19N3O4/c33-25-14-29(28(35)31-25,24-13-21-23(37-24)7-4-10-30-21)16-32-15-18-8-9-22-20(26(18)27(32)34)12-19(36-22)11-17-5-2-1-3-6-17;1-12-4-13-5-14-10-32(24(34)21(14)22(27)23(13)36-12)11-26(7-20(33)31-25(26)35)19-6-17-18(37-19)3-2-16(30-17)15-8-28-29-9-15;29-21-10-25(24(31)27-21,20-9-16-18(33-20)2-1-7-26-16)12-28-11-14-5-6-17-15(22(14)23(28)30)8-19(32-17)13-3-4-13;1-31-11-14-7-15-17(32-14)5-4-13-10-27(22(29)21(13)15)12-24(9-20(28)26-23(24)30)19-8-16-18(33-19)3-2-6-25-16;1-13-7-14-4-5-15-11-27(22(29)21(15)16(14)8-13)12-24(10-20(28)26-23(24)30)19-9-17-18(31-19)3-2-6-25-17/h1-10,12-13H,11,14-16H2,(H,31,33,35);2-6,8-9H,7,10-11H2,1H3,(H,28,29)(H,31,33,35);1-2,5-9,13H,3-4,10-12H2,(H,27,29,31);2-8H,9-12H2,1H3,(H,26,28,30);2-6,8-9H,7,10-12H2,1H3,(H,26,28,30)/t29-;;25-;2*24-/m1.111/s1
• InChIKey: BGMHBPGDZUCVQD-GQEAUGLNSA-N
• XLogP: 16.24
• TPSA: 553.02 Ų
• H-Bond Donors: 6
• H-Bond Acceptors: 31
• Rotatable Bonds: 21
• Heavy Atoms: 171
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2291.27
LogP ≤ 5	16.24
H-Bond Donors ≤ 5	6
H-Bond Acceptors ≤ 10	31

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': 'phthalimide', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of (3R)-3-[(7-benzyl-1-oxo-3H-furo[3,2-e]isoindol-2-yl)methyl]-3-furo[3,2-b]pyridin-2-ylpyrrolidine-2,5-dione;(3R)-3-[(7-cyclopropyl-1-oxo-3H-furo[3,2-e]isoindol-2-yl)methyl]-3-furo[3,2-b]pyridin-2-ylpyrrolidine-2,5-dione;3-[(8-fluoro-2-methyl-7-oxo-5H-furo[2,3-f]isoindol-6-yl)methyl]-3-[5-(1H-pyrazol-4-yl)furo[3,2-b]pyridin-2-yl]pyrrolidine-2,5-dione;(3R)-3-furo[3,2-b]pyridin-2-yl-3-[[7-(methoxymethyl)-1-oxo-3H-furo[3,2-e]isoindol-2-yl]methyl]pyrrolidine-2,5-dione;(3R)-3-furo[3,2-b]pyridin-2-yl-3-[(7-methyl-1-oxo-3,6-dihydrocyclopenta[e]isoindol-2-yl)methyl]pyrrolidine-2,5-dione?

The IUPAC name of (3R)-3-[(7-benzyl-1-oxo-3H-furo[3,2-e]isoindol-2-yl)methyl]-3-furo[3,2-b]pyridin-2-ylpyrrolidine-2,5-dione;(3R)-3-[(7-cyclopropyl-1-oxo-3H-furo[3,2-e]isoindol-2-yl)methyl]-3-furo[3,2-b]pyridin-2-ylpyrrolidine-2,5-dione;3-[(8-fluoro-2-methyl-7-oxo-5H-furo[2,3-f]isoindol-6-yl)methyl]-3-[5-(1H-pyrazol-4-yl)furo[3,2-b]pyridin-2-yl]pyrrolidine-2,5-dione;(3R)-3-furo[3,2-b]pyridin-2-yl-3-[[7-(methoxymethyl)-1-oxo-3H-furo[3,2-e]isoindol-2-yl]methyl]pyrrolidine-2,5-dione;(3R)-3-furo[3,2-b]pyridin-2-yl-3-[(7-methyl-1-oxo-3,6-dihydrocyclopenta[e]isoindol-2-yl)methyl]pyrrolidine-2,5-dione (CID 157341836) is (3R)-3-[(7-benzyl-1-oxo-3H-furo[3,2-e]isoindol-2-yl)methyl]-3-furo[3,2-b]pyridin-2-ylpyrrolidine-2,5-dione;(3R)-3-[(7-cyclopropyl-1-oxo-3H-furo[3,2-e]isoindol-2-yl)methyl]-3-furo[3,2-b]pyridin-2-ylpyrrolidine-2,5-dione;3-[(8-fluoro-2-methyl-7-oxo-5H-furo[2,3-f]isoindol-6-yl)methyl]-3-[5-(1H-pyrazol-4-yl)furo[3,2-b]pyridin-2-yl]pyrrolidine-2,5-dione;(3R)-3-furo[3,2-b]pyridin-2-yl-3-[[7-(methoxymethyl)-1-oxo-3H-furo[3,2-e]isoindol-2-yl]methyl]pyrrolidine-2,5-dione;(3R)-3-furo[3,2-b]pyridin-2-yl-3-[(7-methyl-1-oxo-3,6-dihydrocyclopenta[e]isoindol-2-yl)methyl]pyrrolidine-2,5-dione.

What is the SMILES notation for (3R)-3-[(7-benzyl-1-oxo-3H-furo[3,2-e]isoindol-2-yl)methyl]-3-furo[3,2-b]pyridin-2-ylpyrrolidine-2,5-dione;(3R)-3-[(7-cyclopropyl-1-oxo-3H-furo[3,2-e]isoindol-2-yl)methyl]-3-furo[3,2-b]pyridin-2-ylpyrrolidine-2,5-dione;3-[(8-fluoro-2-methyl-7-oxo-5H-furo[2,3-f]isoindol-6-yl)methyl]-3-[5-(1H-pyrazol-4-yl)furo[3,2-b]pyridin-2-yl]pyrrolidine-2,5-dione;(3R)-3-furo[3,2-b]pyridin-2-yl-3-[[7-(methoxymethyl)-1-oxo-3H-furo[3,2-e]isoindol-2-yl]methyl]pyrrolidine-2,5-dione;(3R)-3-furo[3,2-b]pyridin-2-yl-3-[(7-methyl-1-oxo-3,6-dihydrocyclopenta[e]isoindol-2-yl)methyl]pyrrolidine-2,5-dione?

The canonical SMILES for (3R)-3-[(7-benzyl-1-oxo-3H-furo[3,2-e]isoindol-2-yl)methyl]-3-furo[3,2-b]pyridin-2-ylpyrrolidine-2,5-dione;(3R)-3-[(7-cyclopropyl-1-oxo-3H-furo[3,2-e]isoindol-2-yl)methyl]-3-furo[3,2-b]pyridin-2-ylpyrrolidine-2,5-dione;3-[(8-fluoro-2-methyl-7-oxo-5H-furo[2,3-f]isoindol-6-yl)methyl]-3-[5-(1H-pyrazol-4-yl)furo[3,2-b]pyridin-2-yl]pyrrolidine-2,5-dione;(3R)-3-furo[3,2-b]pyridin-2-yl-3-[[7-(methoxymethyl)-1-oxo-3H-furo[3,2-e]isoindol-2-yl]methyl]pyrrolidine-2,5-dione;(3R)-3-furo[3,2-b]pyridin-2-yl-3-[(7-methyl-1-oxo-3,6-dihydrocyclopenta[e]isoindol-2-yl)methyl]pyrrolidine-2,5-dione is CC1=Cc2c(ccc3c2C(=O)N(C[C@@]2(c4cc5ncccc5o4)CC(=O)NC2=O)C3)C1.COCc1cc2c3c(ccc2o1)CN(C[C@@]1(c2cc4ncccc4o2)CC(=O)NC1=O)C3=O.Cc1cc2cc3c(c(F)c2o1)C(=O)N(CC1(c2cc4nc(-c5cn[nH]c5)ccc4o2)CC(=O)NC1=O)C3.O=C1C[C@@](CN2Cc3ccc4oc(C5CC5)cc4c3C2=O)(c2cc3ncccc3o2)C(=O)N1.O=C1C[C@@](CN2Cc3ccc4oc(Cc5ccccc5)cc4c3C2=O)(c2cc3ncccc3o2)C(=O)N1.

What is the InChIKey of (3R)-3-[(7-benzyl-1-oxo-3H-furo[3,2-e]isoindol-2-yl)methyl]-3-furo[3,2-b]pyridin-2-ylpyrrolidine-2,5-dione;(3R)-3-[(7-cyclopropyl-1-oxo-3H-furo[3,2-e]isoindol-2-yl)methyl]-3-furo[3,2-b]pyridin-2-ylpyrrolidine-2,5-dione;3-[(8-fluoro-2-methyl-7-oxo-5H-furo[2,3-f]isoindol-6-yl)methyl]-3-[5-(1H-pyrazol-4-yl)furo[3,2-b]pyridin-2-yl]pyrrolidine-2,5-dione;(3R)-3-furo[3,2-b]pyridin-2-yl-3-[[7-(methoxymethyl)-1-oxo-3H-furo[3,2-e]isoindol-2-yl]methyl]pyrrolidine-2,5-dione;(3R)-3-furo[3,2-b]pyridin-2-yl-3-[(7-methyl-1-oxo-3,6-dihydrocyclopenta[e]isoindol-2-yl)methyl]pyrrolidine-2,5-dione?

The InChIKey is BGMHBPGDZUCVQD-GQEAUGLNSA-N. The full InChI is InChI=1S/C29H21N3O5.C26H18FN5O5.C25H19N3O5.C24H19N3O6.C24H19N3O4/c33-25-14-29(28(35)31-25,24-13-21-23(37-24)7-4-10-30-21)16-32-15-18-8-9-22-20(26(18)27(32)34)12-19(36-22)11-17-5-2-1-3-6-17;1-12-4-13-5-14-10-32(24(34)21(14)22(27)23(13)36-12)11-26(7-20(33)31-25(26)35)19-6-17-18(37-19)3-2-16(30-17)15-8-28-29-9-15;29-21-10-25(24(31)27-21,20-9-16-18(33-20)2-1-7-26-16)12-28-11-14-5-6-17-15(22(14)23(28)30)8-19(32-17)13-3-4-13;1-31-11-14-7-15-17(32-14)5-4-13-10-27(22(29)21(13)15)12-24(9-20(28)26-23(24)30)19-8-16-18(33-19)3-2-6-25-16;1-13-7-14-4-5-15-11-27(22(29)21(15)16(14)8-13)12-24(10-20(28)26-23(24)30)19-9-17-18(31-19)3-2-6-25-17/h1-10,12-13H,11,14-16H2,(H,31,33,35);2-6,8-9H,7,10-11H2,1H3,(H,28,29)(H,31,33,35);1-2,5-9,13H,3-4,10-12H2,(H,27,29,31);2-8H,9-12H2,1H3,(H,26,28,30);2-6,8-9H,7,10-12H2,1H3,(H,26,28,30)/t29-;;25-;2*24-/m1.111/s1.

What are the key properties of (3R)-3-[(7-benzyl-1-oxo-3H-furo[3,2-e]isoindol-2-yl)methyl]-3-furo[3,2-b]pyridin-2-ylpyrrolidine-2,5-dione;(3R)-3-[(7-cyclopropyl-1-oxo-3H-furo[3,2-e]isoindol-2-yl)methyl]-3-furo[3,2-b]pyridin-2-ylpyrrolidine-2,5-dione;3-[(8-fluoro-2-methyl-7-oxo-5H-furo[2,3-f]isoindol-6-yl)methyl]-3-[5-(1H-pyrazol-4-yl)furo[3,2-b]pyridin-2-yl]pyrrolidine-2,5-dione;(3R)-3-furo[3,2-b]pyridin-2-yl-3-[[7-(methoxymethyl)-1-oxo-3H-furo[3,2-e]isoindol-2-yl]methyl]pyrrolidine-2,5-dione;(3R)-3-furo[3,2-b]pyridin-2-yl-3-[(7-methyl-1-oxo-3,6-dihydrocyclopenta[e]isoindol-2-yl)methyl]pyrrolidine-2,5-dione?

(3R)-3-[(7-benzyl-1-oxo-3H-furo[3,2-e]isoindol-2-yl)methyl]-3-furo[3,2-b]pyridin-2-ylpyrrolidine-2,5-dione;(3R)-3-[(7-cyclopropyl-1-oxo-3H-furo[3,2-e]isoindol-2-yl)methyl]-3-furo[3,2-b]pyridin-2-ylpyrrolidine-2,5-dione;3-[(8-fluoro-2-methyl-7-oxo-5H-furo[2,3-f]isoindol-6-yl)methyl]-3-[5-(1H-pyrazol-4-yl)furo[3,2-b]pyridin-2-yl]pyrrolidine-2,5-dione;(3R)-3-furo[3,2-b]pyridin-2-yl-3-[[7-(methoxymethyl)-1-oxo-3H-furo[3,2-e]isoindol-2-yl]methyl]pyrrolidine-2,5-dione;(3R)-3-furo[3,2-b]pyridin-2-yl-3-[(7-methyl-1-oxo-3,6-dihydrocyclopenta[e]isoindol-2-yl)methyl]pyrrolidine-2,5-dione has a molecular weight of 2291.27 g/mol, XLogP of 16.24, 21 rotatable bonds, 6 hydrogen bond donors, and 31 hydrogen bond acceptors.

Where does this data come from?

All data for (3R)-3-[(7-benzyl-1-oxo-3H-furo[3,2-e]isoindol-2-yl)methyl]-3-furo[3,2-b]pyridin-2-ylpyrrolidine-2,5-dione;(3R)-3-[(7-cyclopropyl-1-oxo-3H-furo[3,2-e]isoindol-2-yl)methyl]-3-furo[3,2-b]pyridin-2-ylpyrrolidine-2,5-dione;3-[(8-fluoro-2-methyl-7-oxo-5H-furo[2,3-f]isoindol-6-yl)methyl]-3-[5-(1H-pyrazol-4-yl)furo[3,2-b]pyridin-2-yl]pyrrolidine-2,5-dione;(3R)-3-furo[3,2-b]pyridin-2-yl-3-[[7-(methoxymethyl)-1-oxo-3H-furo[3,2-e]isoindol-2-yl]methyl]pyrrolidine-2,5-dione;(3R)-3-furo[3,2-b]pyridin-2-yl-3-[(7-methyl-1-oxo-3,6-dihydrocyclopenta[e]isoindol-2-yl)methyl]pyrrolidine-2,5-dione is sourced from PubChem (CID 157341836), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).