5-(5-amino-3-pyridinyl)-N-(3-benzylphenyl)-1H-indazole-3-carboxamide;N-(3-benzylphenyl)-5-[5-[(4,4-difluoropiperidin-1-yl)methyl]-3-pyridinyl]-1H-indazole-3-carboxamide;N-(3-benzylphenyl)-5-[5-[(3,3-difluoropyrrolidin-1-yl)methyl]-3-pyridinyl]-1H-indazole-3-carboxamide;N-(6-benzyl-3-pyridinyl)-5-[5-[(4-hydroxypiperidin-1-yl)methyl]-3-pyridinyl]-1H-indazole-3-carboxamide;N-(6-benzyl-3-pyridinyl)-5-[5-(morpholin-4-ylmethyl)-3-pyridinyl]-1H-indazole-3-carboxamide

C150H135F4N27O7 — CID 157350161

IUPAC5-(5-amino-3-pyridinyl)-N-(3-benzylphenyl)-1H-indazole-3-carboxamide;N-(3-benzylphenyl)-5-[5-[(4,4-difluoropiperidin-1-yl)methyl]-3-pyridinyl]-1H-indazole-3-carboxamide;N-(3-benzylphenyl)-5-[5-[(3,3-difluoropyrrolidin-1-yl)methyl]-3-pyridinyl]-1H-indazole-3-carboxamide;N-(6-benzyl-3-pyridinyl)-5-[5-[(4-hydroxypiperidin-1-yl)methyl]-3-pyridinyl]-1H-indazole-3-carboxamide;N-(6-benzyl-3-pyridinyl)-5-[5-(morpholin-4-ylmethyl)-3-pyridinyl]-1H-indazole-3-carboxamide
SMILESNc1cncc(-c2ccc3[nH]nc(C(=O)Nc4cccc(Cc5ccccc5)c4)c3c2)c1.O=C(Nc1ccc(Cc2ccccc2)nc1)c1n[nH]c2ccc(-c3cncc(CN4CCC(O)CC4)c3)cc12.O=C(Nc1ccc(Cc2ccccc2)nc1)c1n[nH]c2ccc(-c3cncc(CN4CCOCC4)c3)cc12.O=C(Nc1cccc(Cc2ccccc2)c1)c1n[nH]c2ccc(-c3cncc(CN4CCC(F)(F)C4)c3)cc12.O=C(Nc1cccc(Cc2ccccc2)c1)c1n[nH]c2ccc(-c3cncc(CN4CCC(F)(F)CC4)c3)cc12
InChIInChI=1S/C32H29F2N5O.C31H27F2N5O.C31H30N6O2.C30H28N6O2.C26H21N5O/c33-32(34)11-13-39(14-12-32)21-24-16-26(20-35-19-24)25-9-10-29-28(18-25)30(38-37-29)31(40)36-27-8-4-7-23(17-27)15-22-5-2-1-3-6-22;32-31(33)11-12-38(20-31)19-23-14-25(18-34-17-23)24-9-10-28-27(16-24)29(37-36-28)30(39)35-26-8-4-7-22(15-26)13-21-5-2-1-3-6-21;38-27-10-12-37(13-11-27)20-22-14-24(18-32-17-22)23-6-9-29-28(16-23)30(36-35-29)31(39)34-26-8-7-25(33-19-26)15-21-4-2-1-3-5-21;37-30(33-26-8-7-25(32-19-26)15-21-4-2-1-3-5-21)29-27-16-23(6-9-28(27)34-35-29)24-14-22(17-31-18-24)20-36-10-12-38-13-11-36;27-21-13-20(15-28-16-21)19-9-10-24-23(14-19)25(31-30-24)26(32)29-22-8-4-7-18(12-22)11-17-5-2-1-3-6-17/h1-10,16-20H,11-15,21H2,(H,36,40)(H,37,38);1-10,14-18H,11-13,19-20H2,(H,35,39)(H,36,37);1-9,14,16-19,27,38H,10-13,15,20H2,(H,34,39)(H,35,36);1-9,14,16-19H,10-13,15,20H2,(H,33,37)(H,34,35);1-10,12-16H,11,27H2,(H,29,32)(H,30,31)
InChIKeyBHKXJKHCCBTWAQ-UHFFFAOYSA-N
MW2503.90 g/mol
LogP27.57
Rot. Bonds33

About 5-(5-amino-3-pyridinyl)-N-(3-benzylphenyl)-1H-indazole-3-carboxamide;N-(3-benzylphenyl)-5-[5-[(4,4-difluoropiperidin-1-yl)methyl]-3-pyridinyl]-1H-indazole-3-carboxamide;N-(3-benzylphenyl)-5-[5-[(3,3-difluoropyrrolidin-1-yl)methyl]-3-pyridinyl]-1H-indazole-3-carboxamide;N-(6-benzyl-3-pyridinyl)-5-[5-[(4-hydroxypiperidin-1-yl)methyl]-3-pyridinyl]-1H-indazole-3-carboxamide;N-(6-benzyl-3-pyridinyl)-5-[5-(morpholin-4-ylmethyl)-3-pyridinyl]-1H-indazole-3-carboxamide

5-(5-amino-3-pyridinyl)-N-(3-benzylphenyl)-1H-indazole-3-carboxamide;N-(3-benzylphenyl)-5-[5-[(4,4-difluoropiperidin-1-yl)methyl]-3-pyridinyl]-1H-indazole-3-carboxamide;N-(3-benzylphenyl)-5-[5-[(3,3-difluoropyrrolidin-1-yl)methyl]-3-pyridinyl]-1H-indazole-3-carboxamide;N-(6-benzyl-3-pyridinyl)-5-[5-[(4-hydroxypiperidin-1-yl)methyl]-3-pyridinyl]-1H-indazole-3-carboxamide;N-(6-benzyl-3-pyridinyl)-5-[5-(morpholin-4-ylmethyl)-3-pyridinyl]-1H-indazole-3-carboxamide (PubChem CID 157350161) has the molecular formula C150H135F4N27O7 and a molecular weight of 2503.90 g/mol. Its IUPAC name is 5-(5-amino-3-pyridinyl)-N-(3-benzylphenyl)-1H-indazole-3-carboxamide;N-(3-benzylphenyl)-5-[5-[(4,4-difluoropiperidin-1-yl)methyl]-3-pyridinyl]-1H-indazole-3-carboxamide;N-(3-benzylphenyl)-5-[5-[(3,3-difluoropyrrolidin-1-yl)methyl]-3-pyridinyl]-1H-indazole-3-carboxamide;N-(6-benzyl-3-pyridinyl)-5-[5-[(4-hydroxypiperidin-1-yl)methyl]-3-pyridinyl]-1H-indazole-3-carboxamide;N-(6-benzyl-3-pyridinyl)-5-[5-(morpholin-4-ylmethyl)-3-pyridinyl]-1H-indazole-3-carboxamide.

Molecular Properties

Compound Name5-(5-amino-3-pyridinyl)-N-(3-benzylphenyl)-1H-indazole-3-carboxamide;N-(3-benzylphenyl)-5-[5-[(4,4-difluoropiperidin-1-yl)methyl]-3-pyridinyl]-1H-indazole-3-carboxamide;N-(3-benzylphenyl)-5-[5-[(3,3-difluoropyrrolidin-1-yl)methyl]-3-pyridinyl]-1H-indazole-3-carboxamide;N-(6-benzyl-3-pyridinyl)-5-[5-[(4-hydroxypiperidin-1-yl)methyl]-3-pyridinyl]-1H-indazole-3-carboxamide;N-(6-benzyl-3-pyridinyl)-5-[5-(morpholin-4-ylmethyl)-3-pyridinyl]-1H-indazole-3-carboxamide
PubChem CID157350161
Molecular FormulaC150H135F4N27O7
Molecular Weight2503.90 g/mol
Exact Mass2502.10
IUPAC Name5-(5-amino-3-pyridinyl)-N-(3-benzylphenyl)-1H-indazole-3-carboxamide;N-(3-benzylphenyl)-5-[5-[(4,4-difluoropiperidin-1-yl)methyl]-3-pyridinyl]-1H-indazole-3-carboxamide;N-(3-benzylphenyl)-5-[5-[(3,3-difluoropyrrolidin-1-yl)methyl]-3-pyridinyl]-1H-indazole-3-carboxamide;N-(6-benzyl-3-pyridinyl)-5-[5-[(4-hydroxypiperidin-1-yl)methyl]-3-pyridinyl]-1H-indazole-3-carboxamide;N-(6-benzyl-3-pyridinyl)-5-[5-(morpholin-4-ylmethyl)-3-pyridinyl]-1H-indazole-3-carboxamide
SMILESNc1cncc(-c2ccc3[nH]nc(C(=O)Nc4cccc(Cc5ccccc5)c4)c3c2)c1.O=C(Nc1ccc(Cc2ccccc2)nc1)c1n[nH]c2ccc(-c3cncc(CN4CCC(O)CC4)c3)cc12.O=C(Nc1ccc(Cc2ccccc2)nc1)c1n[nH]c2ccc(-c3cncc(CN4CCOCC4)c3)cc12.O=C(Nc1cccc(Cc2ccccc2)c1)c1n[nH]c2ccc(-c3cncc(CN4CCC(F)(F)C4)c3)cc12.O=C(Nc1cccc(Cc2ccccc2)c1)c1n[nH]c2ccc(-c3cncc(CN4CCC(F)(F)CC4)c3)cc12
InChIInChI=1S/C32H29F2N5O.C31H27F2N5O.C31H30N6O2.C30H28N6O2.C26H21N5O/c33-32(34)11-13-39(14-12-32)21-24-16-26(20-35-19-24)25-9-10-29-28(18-25)30(38-37-29)31(40)36-27-8-4-7-23(17-27)15-22-5-2-1-3-6-22;32-31(33)11-12-38(20-31)19-23-14-25(18-34-17-23)24-9-10-28-27(16-24)29(37-36-28)30(39)35-26-8-4-7-22(15-26)13-21-5-2-1-3-6-21;38-27-10-12-37(13-11-27)20-22-14-24(18-32-17-22)23-6-9-29-28(16-23)30(36-35-29)31(39)34-26-8-7-25(33-19-26)15-21-4-2-1-3-5-21;37-30(33-26-8-7-25(32-19-26)15-21-4-2-1-3-5-21)29-27-16-23(6-9-28(27)34-35-29)24-14-22(17-31-18-24)20-36-10-12-38-13-11-36;27-21-13-20(15-28-16-21)19-9-10-24-23(14-19)25(31-30-24)26(32)29-22-8-4-7-18(12-22)11-17-5-2-1-3-6-17/h1-10,16-20H,11-15,21H2,(H,36,40)(H,37,38);1-10,14-18H,11-13,19-20H2,(H,35,39)(H,36,37);1-9,14,16-19,27,38H,10-13,15,20H2,(H,34,39)(H,35,36);1-9,14,16-19H,10-13,15,20H2,(H,33,37)(H,34,35);1-10,12-16H,11,27H2,(H,29,32)(H,30,31)
InChIKeyBHKXJKHCCBTWAQ-UHFFFAOYSA-N
XLogP27.57
TPSA447.57 Ų
H-Bond Donors12
H-Bond Acceptors24
Rotatable Bonds33
Heavy Atoms188
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5002503.90
LogP ≤ 527.57
H-Bond Donors ≤ 512
H-Bond Acceptors ≤ 1024

Analyze 5-(5-amino-3-pyridinyl)-N-(3-benzylphenyl)-1H-indazole-3-carboxamide;N-(3-benzylphenyl)-5-[5-[(4,4-difluoropiperidin-1-yl)methyl]-3-pyridinyl]-1H-indazole-3-carboxamide;N-(3-benzylphenyl)-5-[5-[(3,3-difluoropyrrolidin-1-yl)methyl]-3-pyridinyl]-1H-indazole-3-carboxamide;N-(6-benzyl-3-pyridinyl)-5-[5-[(4-hydroxypiperidin-1-yl)methyl]-3-pyridinyl]-1H-indazole-3-carboxamide;N-(6-benzyl-3-pyridinyl)-5-[5-(morpholin-4-ylmethyl)-3-pyridinyl]-1H-indazole-3-carboxamide with MolForge

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Launch Full Analysis

Related Compounds

5-[5-[(3,3-difluoropyrrolidin-1-yl)methyl]pyridin-3-yl]-N-[6-(morpholin-4-ylmethyl)pyridin-3-yl]-1H-indazole-3-carboxamide
CID 89450648
5-[5-[(4,4-difluoropiperidin-1-yl)methyl]pyridin-3-yl]-N-[6-(morpholin-4-ylmethyl)pyridin-3-yl]-1H-indazole-3-carboxamide
CID 89450649
5-[5-[(4-hydroxypiperidin-1-yl)methyl]pyridin-3-yl]-N-[6-(trifluoromethyl)pyridin-3-yl]-1H-indazole-3-carboxamide
CID 89450781
N-[6-(3-fluorophenyl)-3-pyridinyl]-5-[5-[(4-hydroxypiperidin-1-yl)methyl]-3-pyridinyl]-1H-indazole-3-carboxamide
CID 89450992
5-(5-morpholin-4-ylpyridin-3-yl)-N-[6-(trifluoromethyl)pyridin-3-yl]-1H-indazole-3-carboxamide
CID 89451083
5-[5-(morpholin-4-ylmethyl)pyridin-3-yl]-N-[6-(trifluoromethyl)pyridin-3-yl]-1H-indazole-3-carboxamide
CID 89451095
N-[6-(2-fluorophenyl)-3-pyridinyl]-5-[5-[(4-hydroxypiperidin-1-yl)methyl]-3-pyridinyl]-1H-indazole-3-carboxamide
CID 89451177
5-[5-[(4-hydroxypiperidin-1-yl)methyl]-3-pyridinyl]-N-[6-(trifluoromethyl)-3-pyridinyl]-1H-indazole-3-carbohydrazide
CID 89451213
N-[6-(4-fluorophenyl)-3-pyridinyl]-5-[5-[(4-hydroxypiperidin-1-yl)methyl]-3-pyridinyl]-1H-indazole-3-carboxamide
CID 89451272
5-[5-[(4-hydroxypiperidin-1-yl)methyl]pyridin-3-yl]-N-[2-(trifluoromethyl)pyridin-4-yl]-1H-indazole-3-carboxamide
CID 118381729
5-(5-morpholin-4-ylpyridin-3-yl)-N-[2-(trifluoromethyl)pyridin-4-yl]-1H-indazole-3-carboxamide
CID 118382065
5-[5-[(4-hydroxypiperidin-1-yl)methyl]pyridin-3-yl]-N-[5-(trifluoromethyl)pyridin-3-yl]-1H-indazole-3-carboxamide
CID 118382104

Frequently Asked Questions

What is the IUPAC name of 5-(5-amino-3-pyridinyl)-N-(3-benzylphenyl)-1H-indazole-3-carboxamide;N-(3-benzylphenyl)-5-[5-[(4,4-difluoropiperidin-1-yl)methyl]-3-pyridinyl]-1H-indazole-3-carboxamide;N-(3-benzylphenyl)-5-[5-[(3,3-difluoropyrrolidin-1-yl)methyl]-3-pyridinyl]-1H-indazole-3-carboxamide;N-(6-benzyl-3-pyridinyl)-5-[5-[(4-hydroxypiperidin-1-yl)methyl]-3-pyridinyl]-1H-indazole-3-carboxamide;N-(6-benzyl-3-pyridinyl)-5-[5-(morpholin-4-ylmethyl)-3-pyridinyl]-1H-indazole-3-carboxamide?
The IUPAC name of 5-(5-amino-3-pyridinyl)-N-(3-benzylphenyl)-1H-indazole-3-carboxamide;N-(3-benzylphenyl)-5-[5-[(4,4-difluoropiperidin-1-yl)methyl]-3-pyridinyl]-1H-indazole-3-carboxamide;N-(3-benzylphenyl)-5-[5-[(3,3-difluoropyrrolidin-1-yl)methyl]-3-pyridinyl]-1H-indazole-3-carboxamide;N-(6-benzyl-3-pyridinyl)-5-[5-[(4-hydroxypiperidin-1-yl)methyl]-3-pyridinyl]-1H-indazole-3-carboxamide;N-(6-benzyl-3-pyridinyl)-5-[5-(morpholin-4-ylmethyl)-3-pyridinyl]-1H-indazole-3-carboxamide (CID 157350161) is 5-(5-amino-3-pyridinyl)-N-(3-benzylphenyl)-1H-indazole-3-carboxamide;N-(3-benzylphenyl)-5-[5-[(4,4-difluoropiperidin-1-yl)methyl]-3-pyridinyl]-1H-indazole-3-carboxamide;N-(3-benzylphenyl)-5-[5-[(3,3-difluoropyrrolidin-1-yl)methyl]-3-pyridinyl]-1H-indazole-3-carboxamide;N-(6-benzyl-3-pyridinyl)-5-[5-[(4-hydroxypiperidin-1-yl)methyl]-3-pyridinyl]-1H-indazole-3-carboxamide;N-(6-benzyl-3-pyridinyl)-5-[5-(morpholin-4-ylmethyl)-3-pyridinyl]-1H-indazole-3-carboxamide.
What is the SMILES notation for 5-(5-amino-3-pyridinyl)-N-(3-benzylphenyl)-1H-indazole-3-carboxamide;N-(3-benzylphenyl)-5-[5-[(4,4-difluoropiperidin-1-yl)methyl]-3-pyridinyl]-1H-indazole-3-carboxamide;N-(3-benzylphenyl)-5-[5-[(3,3-difluoropyrrolidin-1-yl)methyl]-3-pyridinyl]-1H-indazole-3-carboxamide;N-(6-benzyl-3-pyridinyl)-5-[5-[(4-hydroxypiperidin-1-yl)methyl]-3-pyridinyl]-1H-indazole-3-carboxamide;N-(6-benzyl-3-pyridinyl)-5-[5-(morpholin-4-ylmethyl)-3-pyridinyl]-1H-indazole-3-carboxamide?
The canonical SMILES for 5-(5-amino-3-pyridinyl)-N-(3-benzylphenyl)-1H-indazole-3-carboxamide;N-(3-benzylphenyl)-5-[5-[(4,4-difluoropiperidin-1-yl)methyl]-3-pyridinyl]-1H-indazole-3-carboxamide;N-(3-benzylphenyl)-5-[5-[(3,3-difluoropyrrolidin-1-yl)methyl]-3-pyridinyl]-1H-indazole-3-carboxamide;N-(6-benzyl-3-pyridinyl)-5-[5-[(4-hydroxypiperidin-1-yl)methyl]-3-pyridinyl]-1H-indazole-3-carboxamide;N-(6-benzyl-3-pyridinyl)-5-[5-(morpholin-4-ylmethyl)-3-pyridinyl]-1H-indazole-3-carboxamide is Nc1cncc(-c2ccc3[nH]nc(C(=O)Nc4cccc(Cc5ccccc5)c4)c3c2)c1.O=C(Nc1ccc(Cc2ccccc2)nc1)c1n[nH]c2ccc(-c3cncc(CN4CCC(O)CC4)c3)cc12.O=C(Nc1ccc(Cc2ccccc2)nc1)c1n[nH]c2ccc(-c3cncc(CN4CCOCC4)c3)cc12.O=C(Nc1cccc(Cc2ccccc2)c1)c1n[nH]c2ccc(-c3cncc(CN4CCC(F)(F)C4)c3)cc12.O=C(Nc1cccc(Cc2ccccc2)c1)c1n[nH]c2ccc(-c3cncc(CN4CCC(F)(F)CC4)c3)cc12.
What is the InChIKey of 5-(5-amino-3-pyridinyl)-N-(3-benzylphenyl)-1H-indazole-3-carboxamide;N-(3-benzylphenyl)-5-[5-[(4,4-difluoropiperidin-1-yl)methyl]-3-pyridinyl]-1H-indazole-3-carboxamide;N-(3-benzylphenyl)-5-[5-[(3,3-difluoropyrrolidin-1-yl)methyl]-3-pyridinyl]-1H-indazole-3-carboxamide;N-(6-benzyl-3-pyridinyl)-5-[5-[(4-hydroxypiperidin-1-yl)methyl]-3-pyridinyl]-1H-indazole-3-carboxamide;N-(6-benzyl-3-pyridinyl)-5-[5-(morpholin-4-ylmethyl)-3-pyridinyl]-1H-indazole-3-carboxamide?
The InChIKey is BHKXJKHCCBTWAQ-UHFFFAOYSA-N. The full InChI is InChI=1S/C32H29F2N5O.C31H27F2N5O.C31H30N6O2.C30H28N6O2.C26H21N5O/c33-32(34)11-13-39(14-12-32)21-24-16-26(20-35-19-24)25-9-10-29-28(18-25)30(38-37-29)31(40)36-27-8-4-7-23(17-27)15-22-5-2-1-3-6-22;32-31(33)11-12-38(20-31)19-23-14-25(18-34-17-23)24-9-10-28-27(16-24)29(37-36-28)30(39)35-26-8-4-7-22(15-26)13-21-5-2-1-3-6-21;38-27-10-12-37(13-11-27)20-22-14-24(18-32-17-22)23-6-9-29-28(16-23)30(36-35-29)31(39)34-26-8-7-25(33-19-26)15-21-4-2-1-3-5-21;37-30(33-26-8-7-25(32-19-26)15-21-4-2-1-3-5-21)29-27-16-23(6-9-28(27)34-35-29)24-14-22(17-31-18-24)20-36-10-12-38-13-11-36;27-21-13-20(15-28-16-21)19-9-10-24-23(14-19)25(31-30-24)26(32)29-22-8-4-7-18(12-22)11-17-5-2-1-3-6-17/h1-10,16-20H,11-15,21H2,(H,36,40)(H,37,38);1-10,14-18H,11-13,19-20H2,(H,35,39)(H,36,37);1-9,14,16-19,27,38H,10-13,15,20H2,(H,34,39)(H,35,36);1-9,14,16-19H,10-13,15,20H2,(H,33,37)(H,34,35);1-10,12-16H,11,27H2,(H,29,32)(H,30,31).
What are the key properties of 5-(5-amino-3-pyridinyl)-N-(3-benzylphenyl)-1H-indazole-3-carboxamide;N-(3-benzylphenyl)-5-[5-[(4,4-difluoropiperidin-1-yl)methyl]-3-pyridinyl]-1H-indazole-3-carboxamide;N-(3-benzylphenyl)-5-[5-[(3,3-difluoropyrrolidin-1-yl)methyl]-3-pyridinyl]-1H-indazole-3-carboxamide;N-(6-benzyl-3-pyridinyl)-5-[5-[(4-hydroxypiperidin-1-yl)methyl]-3-pyridinyl]-1H-indazole-3-carboxamide;N-(6-benzyl-3-pyridinyl)-5-[5-(morpholin-4-ylmethyl)-3-pyridinyl]-1H-indazole-3-carboxamide?
5-(5-amino-3-pyridinyl)-N-(3-benzylphenyl)-1H-indazole-3-carboxamide;N-(3-benzylphenyl)-5-[5-[(4,4-difluoropiperidin-1-yl)methyl]-3-pyridinyl]-1H-indazole-3-carboxamide;N-(3-benzylphenyl)-5-[5-[(3,3-difluoropyrrolidin-1-yl)methyl]-3-pyridinyl]-1H-indazole-3-carboxamide;N-(6-benzyl-3-pyridinyl)-5-[5-[(4-hydroxypiperidin-1-yl)methyl]-3-pyridinyl]-1H-indazole-3-carboxamide;N-(6-benzyl-3-pyridinyl)-5-[5-(morpholin-4-ylmethyl)-3-pyridinyl]-1H-indazole-3-carboxamide has a molecular weight of 2503.90 g/mol, XLogP of 27.57, 33 rotatable bonds, 12 hydrogen bond donors, and 24 hydrogen bond acceptors.
Where does this data come from?
All data for 5-(5-amino-3-pyridinyl)-N-(3-benzylphenyl)-1H-indazole-3-carboxamide;N-(3-benzylphenyl)-5-[5-[(4,4-difluoropiperidin-1-yl)methyl]-3-pyridinyl]-1H-indazole-3-carboxamide;N-(3-benzylphenyl)-5-[5-[(3,3-difluoropyrrolidin-1-yl)methyl]-3-pyridinyl]-1H-indazole-3-carboxamide;N-(6-benzyl-3-pyridinyl)-5-[5-[(4-hydroxypiperidin-1-yl)methyl]-3-pyridinyl]-1H-indazole-3-carboxamide;N-(6-benzyl-3-pyridinyl)-5-[5-(morpholin-4-ylmethyl)-3-pyridinyl]-1H-indazole-3-carboxamide is sourced from PubChem (CID 157350161), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).