1-[3-(3-chloro-4-fluorophenyl)pyrido[2,3-b]pyrazin-6-yl]-3-ethylurea;1-[3-[6-chloro-5-(trifluoromethyl)-3-pyridinyl]pyrido[2,3-b]pyrazin-6-yl]-3-ethylurea;1-[3-(cyclopropylmethylamino)pyrido[2,3-b]pyrazin-6-yl]-3-ethylurea;1-[3-(2,4-difluorophenyl)pyrido[2,3-b]pyrazin-6-yl]-3-ethylurea;4-[6-(ethylcarbamoylamino)pyrido[2,3-b]pyrazin-3-yl]benzoic acid;N-[4-[6-(ethylcarbamoylamino)pyrido[2,3-b]pyrazin-3-yl]phenyl]acetamide;1-ethyl-3-[3-(4-fluorophenyl)pyrido[2,3-b]pyrazin-6-yl]urea;1-ethyl-3-[3-(2-hydroxyphenyl)pyrido[2,3-b]pyrazin-6-yl]urea;1-ethyl-3-[3-(2-methoxyethylamino)pyrido[2,3-b]pyrazin-6-yl]urea;1-ethyl-3-[3-(4-methylpiperazin-1-yl)pyrido[2,3-b]pyrazin-6-yl]urea;1-ethyl-3-(3-morpholin-4-ylpyrido[2,3-b]pyrazin-6-yl)urea;1-ethyl-3-(3-phenoxypyrido[2,3-b]pyrazin-6-yl)urea

C187H190Cl2F7N67O19 — CID 157358120

About 1-[3-(3-chloro-4-fluorophenyl)pyrido[2,3-b]pyrazin-6-yl]-3-ethylurea;1-[3-[6-chloro-5-(trifluoromethyl)-3-pyridinyl]pyrido[2,3-b]pyrazin-6-yl]-3-ethylurea;1-[3-(cyclopropylmethylamino)pyrido[2,3-b]pyrazin-6-yl]-3-ethylurea;1-[3-(2,4-difluorophenyl)pyrido[2,3-b]pyrazin-6-yl]-3-ethylurea;4-[6-(ethylcarbamoylamino)pyrido[2,3-b]pyrazin-3-yl]benzoic acid;N-[4-[6-(ethylcarbamoylamino)pyrido[2,3-b]pyrazin-3-yl]phenyl]acetamide;1-ethyl-3-[3-(4-fluorophenyl)pyrido[2,3-b]pyrazin-6-yl]urea;1-ethyl-3-[3-(2-hydroxyphenyl)pyrido[2,3-b]pyrazin-6-yl]urea;1-ethyl-3-[3-(2-methoxyethylamino)pyrido[2,3-b]pyrazin-6-yl]urea;1-ethyl-3-[3-(4-methylpiperazin-1-yl)pyrido[2,3-b]pyrazin-6-yl]urea;1-ethyl-3-(3-morpholin-4-ylpyrido[2,3-b]pyrazin-6-yl)urea;1-ethyl-3-(3-phenoxypyrido[2,3-b]pyrazin-6-yl)urea

1-[3-(3-chloro-4-fluorophenyl)pyrido[2,3-b]pyrazin-6-yl]-3-ethylurea;1-[3-[6-chloro-5-(trifluoromethyl)-3-pyridinyl]pyrido[2,3-b]pyrazin-6-yl]-3-ethylurea;1-[3-(cyclopropylmethylamino)pyrido[2,3-b]pyrazin-6-yl]-3-ethylurea;1-[3-(2,4-difluorophenyl)pyrido[2,3-b]pyrazin-6-yl]-3-ethylurea;4-[6-(ethylcarbamoylamino)pyrido[2,3-b]pyrazin-3-yl]benzoic acid;N-[4-[6-(ethylcarbamoylamino)pyrido[2,3-b]pyrazin-3-yl]phenyl]acetamide;1-ethyl-3-[3-(4-fluorophenyl)pyrido[2,3-b]pyrazin-6-yl]urea;1-ethyl-3-[3-(2-hydroxyphenyl)pyrido[2,3-b]pyrazin-6-yl]urea;1-ethyl-3-[3-(2-methoxyethylamino)pyrido[2,3-b]pyrazin-6-yl]urea;1-ethyl-3-[3-(4-methylpiperazin-1-yl)pyrido[2,3-b]pyrazin-6-yl]urea;1-ethyl-3-(3-morpholin-4-ylpyrido[2,3-b]pyrazin-6-yl)urea;1-ethyl-3-(3-phenoxypyrido[2,3-b]pyrazin-6-yl)urea (PubChem CID 157358120) has the molecular formula C187H190Cl2F7N67O19 and a molecular weight of 3883.92 g/mol. Its IUPAC name is 1-[3-(3-chloro-4-fluorophenyl)pyrido[2,3-b]pyrazin-6-yl]-3-ethylurea;1-[3-[6-chloro-5-(trifluoromethyl)-3-pyridinyl]pyrido[2,3-b]pyrazin-6-yl]-3-ethylurea;1-[3-(cyclopropylmethylamino)pyrido[2,3-b]pyrazin-6-yl]-3-ethylurea;1-[3-(2,4-difluorophenyl)pyrido[2,3-b]pyrazin-6-yl]-3-ethylurea;4-[6-(ethylcarbamoylamino)pyrido[2,3-b]pyrazin-3-yl]benzoic acid;N-[4-[6-(ethylcarbamoylamino)pyrido[2,3-b]pyrazin-3-yl]phenyl]acetamide;1-ethyl-3-[3-(4-fluorophenyl)pyrido[2,3-b]pyrazin-6-yl]urea;1-ethyl-3-[3-(2-hydroxyphenyl)pyrido[2,3-b]pyrazin-6-yl]urea;1-ethyl-3-[3-(2-methoxyethylamino)pyrido[2,3-b]pyrazin-6-yl]urea;1-ethyl-3-[3-(4-methylpiperazin-1-yl)pyrido[2,3-b]pyrazin-6-yl]urea;1-ethyl-3-(3-morpholin-4-ylpyrido[2,3-b]pyrazin-6-yl)urea;1-ethyl-3-(3-phenoxypyrido[2,3-b]pyrazin-6-yl)urea.

Molecular Properties

• Compound Name: 1-[3-(3-chloro-4-fluorophenyl)pyrido[2,3-b]pyrazin-6-yl]-3-ethylurea;1-[3-[6-chloro-5-(trifluoromethyl)-3-pyridinyl]pyrido[2,3-b]pyrazin-6-yl]-3-ethylurea;1-[3-(cyclopropylmethylamino)pyrido[2,3-b]pyrazin-6-yl]-3-ethylurea;1-[3-(2,4-difluorophenyl)pyrido[2,3-b]pyrazin-6-yl]-3-ethylurea;4-[6-(ethylcarbamoylamino)pyrido[2,3-b]pyrazin-3-yl]benzoic acid;N-[4-[6-(ethylcarbamoylamino)pyrido[2,3-b]pyrazin-3-yl]phenyl]acetamide;1-ethyl-3-[3-(4-fluorophenyl)pyrido[2,3-b]pyrazin-6-yl]urea;1-ethyl-3-[3-(2-hydroxyphenyl)pyrido[2,3-b]pyrazin-6-yl]urea;1-ethyl-3-[3-(2-methoxyethylamino)pyrido[2,3-b]pyrazin-6-yl]urea;1-ethyl-3-[3-(4-methylpiperazin-1-yl)pyrido[2,3-b]pyrazin-6-yl]urea;1-ethyl-3-(3-morpholin-4-ylpyrido[2,3-b]pyrazin-6-yl)urea;1-ethyl-3-(3-phenoxypyrido[2,3-b]pyrazin-6-yl)urea
• PubChem CID: 157358120
• Molecular Formula: C187H190Cl2F7N67O19
• Molecular Weight: 3883.92 g/mol
• Exact Mass: 3880.52
• IUPAC Name: 1-[3-(3-chloro-4-fluorophenyl)pyrido[2,3-b]pyrazin-6-yl]-3-ethylurea;1-[3-[6-chloro-5-(trifluoromethyl)-3-pyridinyl]pyrido[2,3-b]pyrazin-6-yl]-3-ethylurea;1-[3-(cyclopropylmethylamino)pyrido[2,3-b]pyrazin-6-yl]-3-ethylurea;1-[3-(2,4-difluorophenyl)pyrido[2,3-b]pyrazin-6-yl]-3-ethylurea;4-[6-(ethylcarbamoylamino)pyrido[2,3-b]pyrazin-3-yl]benzoic acid;N-[4-[6-(ethylcarbamoylamino)pyrido[2,3-b]pyrazin-3-yl]phenyl]acetamide;1-ethyl-3-[3-(4-fluorophenyl)pyrido[2,3-b]pyrazin-6-yl]urea;1-ethyl-3-[3-(2-hydroxyphenyl)pyrido[2,3-b]pyrazin-6-yl]urea;1-ethyl-3-[3-(2-methoxyethylamino)pyrido[2,3-b]pyrazin-6-yl]urea;1-ethyl-3-[3-(4-methylpiperazin-1-yl)pyrido[2,3-b]pyrazin-6-yl]urea;1-ethyl-3-(3-morpholin-4-ylpyrido[2,3-b]pyrazin-6-yl)urea;1-ethyl-3-(3-phenoxypyrido[2,3-b]pyrazin-6-yl)urea
• SMILES: CCNC(=O)Nc1ccc2ncc(-c3ccc(C(=O)O)cc3)nc2n1.CCNC(=O)Nc1ccc2ncc(-c3ccc(F)c(Cl)c3)nc2n1.CCNC(=O)Nc1ccc2ncc(-c3ccc(F)cc3)nc2n1.CCNC(=O)Nc1ccc2ncc(-c3ccc(F)cc3F)nc2n1.CCNC(=O)Nc1ccc2ncc(-c3ccc(NC(C)=O)cc3)nc2n1.CCNC(=O)Nc1ccc2ncc(-c3ccccc3O)nc2n1.CCNC(=O)Nc1ccc2ncc(-c3cnc(Cl)c(C(F)(F)F)c3)nc2n1.CCNC(=O)Nc1ccc2ncc(N3CCN(C)CC3)nc2n1.CCNC(=O)Nc1ccc2ncc(N3CCOCC3)nc2n1.CCNC(=O)Nc1ccc2ncc(NCC3CC3)nc2n1.CCNC(=O)Nc1ccc2ncc(NCCOC)nc2n1.CCNC(=O)Nc1ccc2ncc(Oc3ccccc3)nc2n1
• InChI: InChI=1S/C18H18N6O2.C17H15N5O3.C16H12ClF3N6O.C16H13ClFN5O.C16H13F2N5O.C16H14FN5O.2C16H15N5O2.C15H21N7O.C14H18N6O2.C14H18N6O.C13H18N6O2/c1-3-19-18(26)24-16-9-8-14-17(23-16)22-15(10-20-14)12-4-6-13(7-5-12)21-11(2)25;1-2-18-17(25)22-14-8-7-12-15(21-14)20-13(9-19-12)10-3-5-11(6-4-10)16(23)24;1-2-21-15(27)26-12-4-3-10-14(25-12)24-11(7-22-10)8-5-9(16(18,19)20)13(17)23-6-8;1-2-19-16(24)23-14-6-5-12-15(22-14)21-13(8-20-12)9-3-4-11(18)10(17)7-9;1-2-19-16(24)23-14-6-5-12-15(22-14)21-13(8-20-12)10-4-3-9(17)7-11(10)18;1-2-18-16(23)22-14-8-7-12-15(21-14)20-13(9-19-12)10-3-5-11(17)6-4-10;1-2-17-16(23)21-14-8-7-11-15(20-14)19-12(9-18-11)10-5-3-4-6-13(10)22;1-2-17-16(22)20-13-9-8-12-15(19-13)21-14(10-18-12)23-11-6-4-3-5-7-11;1-3-16-15(23)19-12-5-4-11-14(18-12)20-13(10-17-11)22-8-6-21(2)7-9-22;1-2-15-14(21)18-11-4-3-10-13(17-11)19-12(9-16-10)20-5-7-22-8-6-20;1-2-15-14(21)20-11-6-5-10-13(18-11)19-12(8-16-10)17-7-9-3-4-9;1-3-14-13(20)19-10-5-4-9-12(17-10)18-11(8-16-9)15-6-7-21-2/h4-10H,3H2,1-2H3,(H,21,25)(H2,19,22,23,24,26);3-9H,2H2,1H3,(H,23,24)(H2,18,20,21,22,25);3-7H,2H2,1H3,(H2,21,24,25,26,27);2*3-8H,2H2,1H3,(H2,19,21,22,23,24);3-9H,2H2,1H3,(H2,18,20,21,22,23);3-9,22H,2H2,1H3,(H2,17,19,20,21,23);3-10H,2H2,1H3,(H2,17,19,20,21,22);4-5,10H,3,6-9H2,1-2H3,(H2,16,18,19,20,23);3-4,9H,2,5-8H2,1H3,(H2,15,17,18,19,21);5-6,8-9H,2-4,7H2,1H3,(H3,15,17,18,19,20,21);4-5,8H,3,6-7H2,1-2H3,(H3,14,15,17,18,19,20)
• InChIKey: BIICLMJKAQOURY-UHFFFAOYSA-N
• XLogP: 29.56
• TPSA: 1118.59 Ų
• H-Bond Donors: 29
• H-Bond Acceptors: 60
• Rotatable Bonds: 44
• Heavy Atoms: 282
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	3883.92
LogP ≤ 5	29.56
H-Bond Donors ≤ 5	29
H-Bond Acceptors ≤ 10	60

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': '2-halo_pyridine', 'substructure': 'N/A'}, {'alert_name': 'Aliphatic_long_chain', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of 1-[3-(3-chloro-4-fluorophenyl)pyrido[2,3-b]pyrazin-6-yl]-3-ethylurea;1-[3-[6-chloro-5-(trifluoromethyl)-3-pyridinyl]pyrido[2,3-b]pyrazin-6-yl]-3-ethylurea;1-[3-(cyclopropylmethylamino)pyrido[2,3-b]pyrazin-6-yl]-3-ethylurea;1-[3-(2,4-difluorophenyl)pyrido[2,3-b]pyrazin-6-yl]-3-ethylurea;4-[6-(ethylcarbamoylamino)pyrido[2,3-b]pyrazin-3-yl]benzoic acid;N-[4-[6-(ethylcarbamoylamino)pyrido[2,3-b]pyrazin-3-yl]phenyl]acetamide;1-ethyl-3-[3-(4-fluorophenyl)pyrido[2,3-b]pyrazin-6-yl]urea;1-ethyl-3-[3-(2-hydroxyphenyl)pyrido[2,3-b]pyrazin-6-yl]urea;1-ethyl-3-[3-(2-methoxyethylamino)pyrido[2,3-b]pyrazin-6-yl]urea;1-ethyl-3-[3-(4-methylpiperazin-1-yl)pyrido[2,3-b]pyrazin-6-yl]urea;1-ethyl-3-(3-morpholin-4-ylpyrido[2,3-b]pyrazin-6-yl)urea;1-ethyl-3-(3-phenoxypyrido[2,3-b]pyrazin-6-yl)urea?

The IUPAC name of 1-[3-(3-chloro-4-fluorophenyl)pyrido[2,3-b]pyrazin-6-yl]-3-ethylurea;1-[3-[6-chloro-5-(trifluoromethyl)-3-pyridinyl]pyrido[2,3-b]pyrazin-6-yl]-3-ethylurea;1-[3-(cyclopropylmethylamino)pyrido[2,3-b]pyrazin-6-yl]-3-ethylurea;1-[3-(2,4-difluorophenyl)pyrido[2,3-b]pyrazin-6-yl]-3-ethylurea;4-[6-(ethylcarbamoylamino)pyrido[2,3-b]pyrazin-3-yl]benzoic acid;N-[4-[6-(ethylcarbamoylamino)pyrido[2,3-b]pyrazin-3-yl]phenyl]acetamide;1-ethyl-3-[3-(4-fluorophenyl)pyrido[2,3-b]pyrazin-6-yl]urea;1-ethyl-3-[3-(2-hydroxyphenyl)pyrido[2,3-b]pyrazin-6-yl]urea;1-ethyl-3-[3-(2-methoxyethylamino)pyrido[2,3-b]pyrazin-6-yl]urea;1-ethyl-3-[3-(4-methylpiperazin-1-yl)pyrido[2,3-b]pyrazin-6-yl]urea;1-ethyl-3-(3-morpholin-4-ylpyrido[2,3-b]pyrazin-6-yl)urea;1-ethyl-3-(3-phenoxypyrido[2,3-b]pyrazin-6-yl)urea (CID 157358120) is 1-[3-(3-chloro-4-fluorophenyl)pyrido[2,3-b]pyrazin-6-yl]-3-ethylurea;1-[3-[6-chloro-5-(trifluoromethyl)-3-pyridinyl]pyrido[2,3-b]pyrazin-6-yl]-3-ethylurea;1-[3-(cyclopropylmethylamino)pyrido[2,3-b]pyrazin-6-yl]-3-ethylurea;1-[3-(2,4-difluorophenyl)pyrido[2,3-b]pyrazin-6-yl]-3-ethylurea;4-[6-(ethylcarbamoylamino)pyrido[2,3-b]pyrazin-3-yl]benzoic acid;N-[4-[6-(ethylcarbamoylamino)pyrido[2,3-b]pyrazin-3-yl]phenyl]acetamide;1-ethyl-3-[3-(4-fluorophenyl)pyrido[2,3-b]pyrazin-6-yl]urea;1-ethyl-3-[3-(2-hydroxyphenyl)pyrido[2,3-b]pyrazin-6-yl]urea;1-ethyl-3-[3-(2-methoxyethylamino)pyrido[2,3-b]pyrazin-6-yl]urea;1-ethyl-3-[3-(4-methylpiperazin-1-yl)pyrido[2,3-b]pyrazin-6-yl]urea;1-ethyl-3-(3-morpholin-4-ylpyrido[2,3-b]pyrazin-6-yl)urea;1-ethyl-3-(3-phenoxypyrido[2,3-b]pyrazin-6-yl)urea.

What is the SMILES notation for 1-[3-(3-chloro-4-fluorophenyl)pyrido[2,3-b]pyrazin-6-yl]-3-ethylurea;1-[3-[6-chloro-5-(trifluoromethyl)-3-pyridinyl]pyrido[2,3-b]pyrazin-6-yl]-3-ethylurea;1-[3-(cyclopropylmethylamino)pyrido[2,3-b]pyrazin-6-yl]-3-ethylurea;1-[3-(2,4-difluorophenyl)pyrido[2,3-b]pyrazin-6-yl]-3-ethylurea;4-[6-(ethylcarbamoylamino)pyrido[2,3-b]pyrazin-3-yl]benzoic acid;N-[4-[6-(ethylcarbamoylamino)pyrido[2,3-b]pyrazin-3-yl]phenyl]acetamide;1-ethyl-3-[3-(4-fluorophenyl)pyrido[2,3-b]pyrazin-6-yl]urea;1-ethyl-3-[3-(2-hydroxyphenyl)pyrido[2,3-b]pyrazin-6-yl]urea;1-ethyl-3-[3-(2-methoxyethylamino)pyrido[2,3-b]pyrazin-6-yl]urea;1-ethyl-3-[3-(4-methylpiperazin-1-yl)pyrido[2,3-b]pyrazin-6-yl]urea;1-ethyl-3-(3-morpholin-4-ylpyrido[2,3-b]pyrazin-6-yl)urea;1-ethyl-3-(3-phenoxypyrido[2,3-b]pyrazin-6-yl)urea?

The canonical SMILES for 1-[3-(3-chloro-4-fluorophenyl)pyrido[2,3-b]pyrazin-6-yl]-3-ethylurea;1-[3-[6-chloro-5-(trifluoromethyl)-3-pyridinyl]pyrido[2,3-b]pyrazin-6-yl]-3-ethylurea;1-[3-(cyclopropylmethylamino)pyrido[2,3-b]pyrazin-6-yl]-3-ethylurea;1-[3-(2,4-difluorophenyl)pyrido[2,3-b]pyrazin-6-yl]-3-ethylurea;4-[6-(ethylcarbamoylamino)pyrido[2,3-b]pyrazin-3-yl]benzoic acid;N-[4-[6-(ethylcarbamoylamino)pyrido[2,3-b]pyrazin-3-yl]phenyl]acetamide;1-ethyl-3-[3-(4-fluorophenyl)pyrido[2,3-b]pyrazin-6-yl]urea;1-ethyl-3-[3-(2-hydroxyphenyl)pyrido[2,3-b]pyrazin-6-yl]urea;1-ethyl-3-[3-(2-methoxyethylamino)pyrido[2,3-b]pyrazin-6-yl]urea;1-ethyl-3-[3-(4-methylpiperazin-1-yl)pyrido[2,3-b]pyrazin-6-yl]urea;1-ethyl-3-(3-morpholin-4-ylpyrido[2,3-b]pyrazin-6-yl)urea;1-ethyl-3-(3-phenoxypyrido[2,3-b]pyrazin-6-yl)urea is CCNC(=O)Nc1ccc2ncc(-c3ccc(C(=O)O)cc3)nc2n1.CCNC(=O)Nc1ccc2ncc(-c3ccc(F)c(Cl)c3)nc2n1.CCNC(=O)Nc1ccc2ncc(-c3ccc(F)cc3)nc2n1.CCNC(=O)Nc1ccc2ncc(-c3ccc(F)cc3F)nc2n1.CCNC(=O)Nc1ccc2ncc(-c3ccc(NC(C)=O)cc3)nc2n1.CCNC(=O)Nc1ccc2ncc(-c3ccccc3O)nc2n1.CCNC(=O)Nc1ccc2ncc(-c3cnc(Cl)c(C(F)(F)F)c3)nc2n1.CCNC(=O)Nc1ccc2ncc(N3CCN(C)CC3)nc2n1.CCNC(=O)Nc1ccc2ncc(N3CCOCC3)nc2n1.CCNC(=O)Nc1ccc2ncc(NCC3CC3)nc2n1.CCNC(=O)Nc1ccc2ncc(NCCOC)nc2n1.CCNC(=O)Nc1ccc2ncc(Oc3ccccc3)nc2n1.

What is the InChIKey of 1-[3-(3-chloro-4-fluorophenyl)pyrido[2,3-b]pyrazin-6-yl]-3-ethylurea;1-[3-[6-chloro-5-(trifluoromethyl)-3-pyridinyl]pyrido[2,3-b]pyrazin-6-yl]-3-ethylurea;1-[3-(cyclopropylmethylamino)pyrido[2,3-b]pyrazin-6-yl]-3-ethylurea;1-[3-(2,4-difluorophenyl)pyrido[2,3-b]pyrazin-6-yl]-3-ethylurea;4-[6-(ethylcarbamoylamino)pyrido[2,3-b]pyrazin-3-yl]benzoic acid;N-[4-[6-(ethylcarbamoylamino)pyrido[2,3-b]pyrazin-3-yl]phenyl]acetamide;1-ethyl-3-[3-(4-fluorophenyl)pyrido[2,3-b]pyrazin-6-yl]urea;1-ethyl-3-[3-(2-hydroxyphenyl)pyrido[2,3-b]pyrazin-6-yl]urea;1-ethyl-3-[3-(2-methoxyethylamino)pyrido[2,3-b]pyrazin-6-yl]urea;1-ethyl-3-[3-(4-methylpiperazin-1-yl)pyrido[2,3-b]pyrazin-6-yl]urea;1-ethyl-3-(3-morpholin-4-ylpyrido[2,3-b]pyrazin-6-yl)urea;1-ethyl-3-(3-phenoxypyrido[2,3-b]pyrazin-6-yl)urea?

The InChIKey is BIICLMJKAQOURY-UHFFFAOYSA-N. The full InChI is InChI=1S/C18H18N6O2.C17H15N5O3.C16H12ClF3N6O.C16H13ClFN5O.C16H13F2N5O.C16H14FN5O.2C16H15N5O2.C15H21N7O.C14H18N6O2.C14H18N6O.C13H18N6O2/c1-3-19-18(26)24-16-9-8-14-17(23-16)22-15(10-20-14)12-4-6-13(7-5-12)21-11(2)25;1-2-18-17(25)22-14-8-7-12-15(21-14)20-13(9-19-12)10-3-5-11(6-4-10)16(23)24;1-2-21-15(27)26-12-4-3-10-14(25-12)24-11(7-22-10)8-5-9(16(18,19)20)13(17)23-6-8;1-2-19-16(24)23-14-6-5-12-15(22-14)21-13(8-20-12)9-3-4-11(18)10(17)7-9;1-2-19-16(24)23-14-6-5-12-15(22-14)21-13(8-20-12)10-4-3-9(17)7-11(10)18;1-2-18-16(23)22-14-8-7-12-15(21-14)20-13(9-19-12)10-3-5-11(17)6-4-10;1-2-17-16(23)21-14-8-7-11-15(20-14)19-12(9-18-11)10-5-3-4-6-13(10)22;1-2-17-16(22)20-13-9-8-12-15(19-13)21-14(10-18-12)23-11-6-4-3-5-7-11;1-3-16-15(23)19-12-5-4-11-14(18-12)20-13(10-17-11)22-8-6-21(2)7-9-22;1-2-15-14(21)18-11-4-3-10-13(17-11)19-12(9-16-10)20-5-7-22-8-6-20;1-2-15-14(21)20-11-6-5-10-13(18-11)19-12(8-16-10)17-7-9-3-4-9;1-3-14-13(20)19-10-5-4-9-12(17-10)18-11(8-16-9)15-6-7-21-2/h4-10H,3H2,1-2H3,(H,21,25)(H2,19,22,23,24,26);3-9H,2H2,1H3,(H,23,24)(H2,18,20,21,22,25);3-7H,2H2,1H3,(H2,21,24,25,26,27);2*3-8H,2H2,1H3,(H2,19,21,22,23,24);3-9H,2H2,1H3,(H2,18,20,21,22,23);3-9,22H,2H2,1H3,(H2,17,19,20,21,23);3-10H,2H2,1H3,(H2,17,19,20,21,22);4-5,10H,3,6-9H2,1-2H3,(H2,16,18,19,20,23);3-4,9H,2,5-8H2,1H3,(H2,15,17,18,19,21);5-6,8-9H,2-4,7H2,1H3,(H3,15,17,18,19,20,21);4-5,8H,3,6-7H2,1-2H3,(H3,14,15,17,18,19,20).

What are the key properties of 1-[3-(3-chloro-4-fluorophenyl)pyrido[2,3-b]pyrazin-6-yl]-3-ethylurea;1-[3-[6-chloro-5-(trifluoromethyl)-3-pyridinyl]pyrido[2,3-b]pyrazin-6-yl]-3-ethylurea;1-[3-(cyclopropylmethylamino)pyrido[2,3-b]pyrazin-6-yl]-3-ethylurea;1-[3-(2,4-difluorophenyl)pyrido[2,3-b]pyrazin-6-yl]-3-ethylurea;4-[6-(ethylcarbamoylamino)pyrido[2,3-b]pyrazin-3-yl]benzoic acid;N-[4-[6-(ethylcarbamoylamino)pyrido[2,3-b]pyrazin-3-yl]phenyl]acetamide;1-ethyl-3-[3-(4-fluorophenyl)pyrido[2,3-b]pyrazin-6-yl]urea;1-ethyl-3-[3-(2-hydroxyphenyl)pyrido[2,3-b]pyrazin-6-yl]urea;1-ethyl-3-[3-(2-methoxyethylamino)pyrido[2,3-b]pyrazin-6-yl]urea;1-ethyl-3-[3-(4-methylpiperazin-1-yl)pyrido[2,3-b]pyrazin-6-yl]urea;1-ethyl-3-(3-morpholin-4-ylpyrido[2,3-b]pyrazin-6-yl)urea;1-ethyl-3-(3-phenoxypyrido[2,3-b]pyrazin-6-yl)urea?

1-[3-(3-chloro-4-fluorophenyl)pyrido[2,3-b]pyrazin-6-yl]-3-ethylurea;1-[3-[6-chloro-5-(trifluoromethyl)-3-pyridinyl]pyrido[2,3-b]pyrazin-6-yl]-3-ethylurea;1-[3-(cyclopropylmethylamino)pyrido[2,3-b]pyrazin-6-yl]-3-ethylurea;1-[3-(2,4-difluorophenyl)pyrido[2,3-b]pyrazin-6-yl]-3-ethylurea;4-[6-(ethylcarbamoylamino)pyrido[2,3-b]pyrazin-3-yl]benzoic acid;N-[4-[6-(ethylcarbamoylamino)pyrido[2,3-b]pyrazin-3-yl]phenyl]acetamide;1-ethyl-3-[3-(4-fluorophenyl)pyrido[2,3-b]pyrazin-6-yl]urea;1-ethyl-3-[3-(2-hydroxyphenyl)pyrido[2,3-b]pyrazin-6-yl]urea;1-ethyl-3-[3-(2-methoxyethylamino)pyrido[2,3-b]pyrazin-6-yl]urea;1-ethyl-3-[3-(4-methylpiperazin-1-yl)pyrido[2,3-b]pyrazin-6-yl]urea;1-ethyl-3-(3-morpholin-4-ylpyrido[2,3-b]pyrazin-6-yl)urea;1-ethyl-3-(3-phenoxypyrido[2,3-b]pyrazin-6-yl)urea has a molecular weight of 3883.92 g/mol, XLogP of 29.56, 44 rotatable bonds, 29 hydrogen bond donors, and 60 hydrogen bond acceptors.

Where does this data come from?

All data for 1-[3-(3-chloro-4-fluorophenyl)pyrido[2,3-b]pyrazin-6-yl]-3-ethylurea;1-[3-[6-chloro-5-(trifluoromethyl)-3-pyridinyl]pyrido[2,3-b]pyrazin-6-yl]-3-ethylurea;1-[3-(cyclopropylmethylamino)pyrido[2,3-b]pyrazin-6-yl]-3-ethylurea;1-[3-(2,4-difluorophenyl)pyrido[2,3-b]pyrazin-6-yl]-3-ethylurea;4-[6-(ethylcarbamoylamino)pyrido[2,3-b]pyrazin-3-yl]benzoic acid;N-[4-[6-(ethylcarbamoylamino)pyrido[2,3-b]pyrazin-3-yl]phenyl]acetamide;1-ethyl-3-[3-(4-fluorophenyl)pyrido[2,3-b]pyrazin-6-yl]urea;1-ethyl-3-[3-(2-hydroxyphenyl)pyrido[2,3-b]pyrazin-6-yl]urea;1-ethyl-3-[3-(2-methoxyethylamino)pyrido[2,3-b]pyrazin-6-yl]urea;1-ethyl-3-[3-(4-methylpiperazin-1-yl)pyrido[2,3-b]pyrazin-6-yl]urea;1-ethyl-3-(3-morpholin-4-ylpyrido[2,3-b]pyrazin-6-yl)urea;1-ethyl-3-(3-phenoxypyrido[2,3-b]pyrazin-6-yl)urea is sourced from PubChem (CID 157358120), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).