3-amino-N-[2-(3-chloro-4-cyclohexylphenyl)ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[(2S)-2-(2,5-difluoro-4-piperidin-1-ylphenyl)propyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-6-ethyl-5-fluoro-N-[2-(4-piperidin-1-ylphenyl)ethyl]thieno[2,3-b]pyridine-2-carboxamide;3-amino-6-methyl-N-[2-(4-piperidin-1-ylphenyl)ethyl]-4-(trifluoromethyl)thieno[2,3-b]pyridine-2-carboxamide;3-amino-6-methyl-N-[(2R)-2-(4-piperidin-1-ylphenyl)propyl]thieno[2,3-b]pyridine-2-carboxamide;3-amino-6-methyl-N-[(2S)-2-(4-piperidin-1-ylphenyl)propyl]thieno[2,3-b]pyridine-2-carboxamide

C138H160ClF6N23O6S6 — CID 157358975

About 3-amino-N-[2-(3-chloro-4-cyclohexylphenyl)ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[(2S)-2-(2,5-difluoro-4-piperidin-1-ylphenyl)propyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-6-ethyl-5-fluoro-N-[2-(4-piperidin-1-ylphenyl)ethyl]thieno[2,3-b]pyridine-2-carboxamide;3-amino-6-methyl-N-[2-(4-piperidin-1-ylphenyl)ethyl]-4-(trifluoromethyl)thieno[2,3-b]pyridine-2-carboxamide;3-amino-6-methyl-N-[(2R)-2-(4-piperidin-1-ylphenyl)propyl]thieno[2,3-b]pyridine-2-carboxamide;3-amino-6-methyl-N-[(2S)-2-(4-piperidin-1-ylphenyl)propyl]thieno[2,3-b]pyridine-2-carboxamide

3-amino-N-[2-(3-chloro-4-cyclohexylphenyl)ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[(2S)-2-(2,5-difluoro-4-piperidin-1-ylphenyl)propyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-6-ethyl-5-fluoro-N-[2-(4-piperidin-1-ylphenyl)ethyl]thieno[2,3-b]pyridine-2-carboxamide;3-amino-6-methyl-N-[2-(4-piperidin-1-ylphenyl)ethyl]-4-(trifluoromethyl)thieno[2,3-b]pyridine-2-carboxamide;3-amino-6-methyl-N-[(2R)-2-(4-piperidin-1-ylphenyl)propyl]thieno[2,3-b]pyridine-2-carboxamide;3-amino-6-methyl-N-[(2S)-2-(4-piperidin-1-ylphenyl)propyl]thieno[2,3-b]pyridine-2-carboxamide (PubChem CID 157358975) has the molecular formula C138H160ClF6N23O6S6 and a molecular weight of 2578.80 g/mol. Its IUPAC name is 3-amino-N-[2-(3-chloro-4-cyclohexylphenyl)ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[(2S)-2-(2,5-difluoro-4-piperidin-1-ylphenyl)propyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-6-ethyl-5-fluoro-N-[2-(4-piperidin-1-ylphenyl)ethyl]thieno[2,3-b]pyridine-2-carboxamide;3-amino-6-methyl-N-[2-(4-piperidin-1-ylphenyl)ethyl]-4-(trifluoromethyl)thieno[2,3-b]pyridine-2-carboxamide;3-amino-6-methyl-N-[(2R)-2-(4-piperidin-1-ylphenyl)propyl]thieno[2,3-b]pyridine-2-carboxamide;3-amino-6-methyl-N-[(2S)-2-(4-piperidin-1-ylphenyl)propyl]thieno[2,3-b]pyridine-2-carboxamide.

Molecular Properties

• Compound Name: 3-amino-N-[2-(3-chloro-4-cyclohexylphenyl)ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[(2S)-2-(2,5-difluoro-4-piperidin-1-ylphenyl)propyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-6-ethyl-5-fluoro-N-[2-(4-piperidin-1-ylphenyl)ethyl]thieno[2,3-b]pyridine-2-carboxamide;3-amino-6-methyl-N-[2-(4-piperidin-1-ylphenyl)ethyl]-4-(trifluoromethyl)thieno[2,3-b]pyridine-2-carboxamide;3-amino-6-methyl-N-[(2R)-2-(4-piperidin-1-ylphenyl)propyl]thieno[2,3-b]pyridine-2-carboxamide;3-amino-6-methyl-N-[(2S)-2-(4-piperidin-1-ylphenyl)propyl]thieno[2,3-b]pyridine-2-carboxamide
• PubChem CID: 157358975
• Molecular Formula: C138H160ClF6N23O6S6
• Molecular Weight: 2578.80 g/mol
• Exact Mass: 2576.08
• IUPAC Name: 3-amino-N-[2-(3-chloro-4-cyclohexylphenyl)ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[(2S)-2-(2,5-difluoro-4-piperidin-1-ylphenyl)propyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-6-ethyl-5-fluoro-N-[2-(4-piperidin-1-ylphenyl)ethyl]thieno[2,3-b]pyridine-2-carboxamide;3-amino-6-methyl-N-[2-(4-piperidin-1-ylphenyl)ethyl]-4-(trifluoromethyl)thieno[2,3-b]pyridine-2-carboxamide;3-amino-6-methyl-N-[(2R)-2-(4-piperidin-1-ylphenyl)propyl]thieno[2,3-b]pyridine-2-carboxamide;3-amino-6-methyl-N-[(2S)-2-(4-piperidin-1-ylphenyl)propyl]thieno[2,3-b]pyridine-2-carboxamide
• SMILES: CCc1nc2sc(C(=O)NCCc3ccc(N4CCCCC4)cc3)c(N)c2cc1F.Cc1cc(C(F)(F)F)c2c(N)c(C(=O)NCCc3ccc(N4CCCCC4)cc3)sc2n1.Cc1ccc2c(N)c(C(=O)NCCc3ccc(C4CCCCC4)c(Cl)c3)sc2n1.Cc1ccc2c(N)c(C(=O)NC[C@@H](C)c3cc(F)c(N4CCCCC4)cc3F)sc2n1.Cc1ccc2c(N)c(C(=O)NC[C@@H](C)c3ccc(N4CCCCC4)cc3)sc2n1.Cc1ccc2c(N)c(C(=O)NC[C@H](C)c3ccc(N4CCCCC4)cc3)sc2n1
• InChI: InChI=1S/C23H26ClN3OS.C23H25F3N4OS.C23H26F2N4OS.C23H27FN4OS.2C23H28N4OS/c1-14-7-9-18-20(25)21(29-23(18)27-14)22(28)26-12-11-15-8-10-17(19(24)13-15)16-5-3-2-4-6-16;1-14-13-17(23(24,25)26)18-19(27)20(32-22(18)29-14)21(31)28-10-9-15-5-7-16(8-6-15)30-11-3-2-4-12-30;1-13(16-10-18(25)19(11-17(16)24)29-8-4-3-5-9-29)12-27-22(30)21-20(26)15-7-6-14(2)28-23(15)31-21;1-2-19-18(24)14-17-20(25)21(30-23(17)27-19)22(29)26-11-10-15-6-8-16(9-7-15)28-12-4-3-5-13-28;2*1-15(17-7-9-18(10-8-17)27-12-4-3-5-13-27)14-25-22(28)21-20(24)19-11-6-16(2)26-23(19)29-21/h7-10,13,16H,2-6,11-12,25H2,1H3,(H,26,28);5-8,13H,2-4,9-12,27H2,1H3,(H,28,31);6-7,10-11,13H,3-5,8-9,12,26H2,1-2H3,(H,27,30);6-9,14H,2-5,10-13,25H2,1H3,(H,26,29);2*6-11,15H,3-5,12-14,24H2,1-2H3,(H,25,28)/t;;13-;;2*15-/m..1.10/s1
• InChIKey: BIKLFTJZPRPEAQ-OLZZFXGQSA-N
• XLogP: 29.98
• TPSA: 424.26 Ų
• H-Bond Donors: 12
• H-Bond Acceptors: 29
• Rotatable Bonds: 31
• Heavy Atoms: 180
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2578.80
LogP ≤ 5	29.98
H-Bond Donors ≤ 5	12
H-Bond Acceptors ≤ 10	29

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': 'anil_di_alk_E(186)', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of 3-amino-N-[2-(3-chloro-4-cyclohexylphenyl)ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[(2S)-2-(2,5-difluoro-4-piperidin-1-ylphenyl)propyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-6-ethyl-5-fluoro-N-[2-(4-piperidin-1-ylphenyl)ethyl]thieno[2,3-b]pyridine-2-carboxamide;3-amino-6-methyl-N-[2-(4-piperidin-1-ylphenyl)ethyl]-4-(trifluoromethyl)thieno[2,3-b]pyridine-2-carboxamide;3-amino-6-methyl-N-[(2R)-2-(4-piperidin-1-ylphenyl)propyl]thieno[2,3-b]pyridine-2-carboxamide;3-amino-6-methyl-N-[(2S)-2-(4-piperidin-1-ylphenyl)propyl]thieno[2,3-b]pyridine-2-carboxamide?

The IUPAC name of 3-amino-N-[2-(3-chloro-4-cyclohexylphenyl)ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[(2S)-2-(2,5-difluoro-4-piperidin-1-ylphenyl)propyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-6-ethyl-5-fluoro-N-[2-(4-piperidin-1-ylphenyl)ethyl]thieno[2,3-b]pyridine-2-carboxamide;3-amino-6-methyl-N-[2-(4-piperidin-1-ylphenyl)ethyl]-4-(trifluoromethyl)thieno[2,3-b]pyridine-2-carboxamide;3-amino-6-methyl-N-[(2R)-2-(4-piperidin-1-ylphenyl)propyl]thieno[2,3-b]pyridine-2-carboxamide;3-amino-6-methyl-N-[(2S)-2-(4-piperidin-1-ylphenyl)propyl]thieno[2,3-b]pyridine-2-carboxamide (CID 157358975) is 3-amino-N-[2-(3-chloro-4-cyclohexylphenyl)ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[(2S)-2-(2,5-difluoro-4-piperidin-1-ylphenyl)propyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-6-ethyl-5-fluoro-N-[2-(4-piperidin-1-ylphenyl)ethyl]thieno[2,3-b]pyridine-2-carboxamide;3-amino-6-methyl-N-[2-(4-piperidin-1-ylphenyl)ethyl]-4-(trifluoromethyl)thieno[2,3-b]pyridine-2-carboxamide;3-amino-6-methyl-N-[(2R)-2-(4-piperidin-1-ylphenyl)propyl]thieno[2,3-b]pyridine-2-carboxamide;3-amino-6-methyl-N-[(2S)-2-(4-piperidin-1-ylphenyl)propyl]thieno[2,3-b]pyridine-2-carboxamide.

What is the SMILES notation for 3-amino-N-[2-(3-chloro-4-cyclohexylphenyl)ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[(2S)-2-(2,5-difluoro-4-piperidin-1-ylphenyl)propyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-6-ethyl-5-fluoro-N-[2-(4-piperidin-1-ylphenyl)ethyl]thieno[2,3-b]pyridine-2-carboxamide;3-amino-6-methyl-N-[2-(4-piperidin-1-ylphenyl)ethyl]-4-(trifluoromethyl)thieno[2,3-b]pyridine-2-carboxamide;3-amino-6-methyl-N-[(2R)-2-(4-piperidin-1-ylphenyl)propyl]thieno[2,3-b]pyridine-2-carboxamide;3-amino-6-methyl-N-[(2S)-2-(4-piperidin-1-ylphenyl)propyl]thieno[2,3-b]pyridine-2-carboxamide?

The canonical SMILES for 3-amino-N-[2-(3-chloro-4-cyclohexylphenyl)ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[(2S)-2-(2,5-difluoro-4-piperidin-1-ylphenyl)propyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-6-ethyl-5-fluoro-N-[2-(4-piperidin-1-ylphenyl)ethyl]thieno[2,3-b]pyridine-2-carboxamide;3-amino-6-methyl-N-[2-(4-piperidin-1-ylphenyl)ethyl]-4-(trifluoromethyl)thieno[2,3-b]pyridine-2-carboxamide;3-amino-6-methyl-N-[(2R)-2-(4-piperidin-1-ylphenyl)propyl]thieno[2,3-b]pyridine-2-carboxamide;3-amino-6-methyl-N-[(2S)-2-(4-piperidin-1-ylphenyl)propyl]thieno[2,3-b]pyridine-2-carboxamide is CCc1nc2sc(C(=O)NCCc3ccc(N4CCCCC4)cc3)c(N)c2cc1F.Cc1cc(C(F)(F)F)c2c(N)c(C(=O)NCCc3ccc(N4CCCCC4)cc3)sc2n1.Cc1ccc2c(N)c(C(=O)NCCc3ccc(C4CCCCC4)c(Cl)c3)sc2n1.Cc1ccc2c(N)c(C(=O)NC[C@@H](C)c3cc(F)c(N4CCCCC4)cc3F)sc2n1.Cc1ccc2c(N)c(C(=O)NC[C@@H](C)c3ccc(N4CCCCC4)cc3)sc2n1.Cc1ccc2c(N)c(C(=O)NC[C@H](C)c3ccc(N4CCCCC4)cc3)sc2n1.

What is the InChIKey of 3-amino-N-[2-(3-chloro-4-cyclohexylphenyl)ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[(2S)-2-(2,5-difluoro-4-piperidin-1-ylphenyl)propyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-6-ethyl-5-fluoro-N-[2-(4-piperidin-1-ylphenyl)ethyl]thieno[2,3-b]pyridine-2-carboxamide;3-amino-6-methyl-N-[2-(4-piperidin-1-ylphenyl)ethyl]-4-(trifluoromethyl)thieno[2,3-b]pyridine-2-carboxamide;3-amino-6-methyl-N-[(2R)-2-(4-piperidin-1-ylphenyl)propyl]thieno[2,3-b]pyridine-2-carboxamide;3-amino-6-methyl-N-[(2S)-2-(4-piperidin-1-ylphenyl)propyl]thieno[2,3-b]pyridine-2-carboxamide?

The InChIKey is BIKLFTJZPRPEAQ-OLZZFXGQSA-N. The full InChI is InChI=1S/C23H26ClN3OS.C23H25F3N4OS.C23H26F2N4OS.C23H27FN4OS.2C23H28N4OS/c1-14-7-9-18-20(25)21(29-23(18)27-14)22(28)26-12-11-15-8-10-17(19(24)13-15)16-5-3-2-4-6-16;1-14-13-17(23(24,25)26)18-19(27)20(32-22(18)29-14)21(31)28-10-9-15-5-7-16(8-6-15)30-11-3-2-4-12-30;1-13(16-10-18(25)19(11-17(16)24)29-8-4-3-5-9-29)12-27-22(30)21-20(26)15-7-6-14(2)28-23(15)31-21;1-2-19-18(24)14-17-20(25)21(30-23(17)27-19)22(29)26-11-10-15-6-8-16(9-7-15)28-12-4-3-5-13-28;2*1-15(17-7-9-18(10-8-17)27-12-4-3-5-13-27)14-25-22(28)21-20(24)19-11-6-16(2)26-23(19)29-21/h7-10,13,16H,2-6,11-12,25H2,1H3,(H,26,28);5-8,13H,2-4,9-12,27H2,1H3,(H,28,31);6-7,10-11,13H,3-5,8-9,12,26H2,1-2H3,(H,27,30);6-9,14H,2-5,10-13,25H2,1H3,(H,26,29);2*6-11,15H,3-5,12-14,24H2,1-2H3,(H,25,28)/t;;13-;;2*15-/m..1.10/s1.

What are the key properties of 3-amino-N-[2-(3-chloro-4-cyclohexylphenyl)ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[(2S)-2-(2,5-difluoro-4-piperidin-1-ylphenyl)propyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-6-ethyl-5-fluoro-N-[2-(4-piperidin-1-ylphenyl)ethyl]thieno[2,3-b]pyridine-2-carboxamide;3-amino-6-methyl-N-[2-(4-piperidin-1-ylphenyl)ethyl]-4-(trifluoromethyl)thieno[2,3-b]pyridine-2-carboxamide;3-amino-6-methyl-N-[(2R)-2-(4-piperidin-1-ylphenyl)propyl]thieno[2,3-b]pyridine-2-carboxamide;3-amino-6-methyl-N-[(2S)-2-(4-piperidin-1-ylphenyl)propyl]thieno[2,3-b]pyridine-2-carboxamide?

3-amino-N-[2-(3-chloro-4-cyclohexylphenyl)ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[(2S)-2-(2,5-difluoro-4-piperidin-1-ylphenyl)propyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-6-ethyl-5-fluoro-N-[2-(4-piperidin-1-ylphenyl)ethyl]thieno[2,3-b]pyridine-2-carboxamide;3-amino-6-methyl-N-[2-(4-piperidin-1-ylphenyl)ethyl]-4-(trifluoromethyl)thieno[2,3-b]pyridine-2-carboxamide;3-amino-6-methyl-N-[(2R)-2-(4-piperidin-1-ylphenyl)propyl]thieno[2,3-b]pyridine-2-carboxamide;3-amino-6-methyl-N-[(2S)-2-(4-piperidin-1-ylphenyl)propyl]thieno[2,3-b]pyridine-2-carboxamide has a molecular weight of 2578.80 g/mol, XLogP of 29.98, 31 rotatable bonds, 12 hydrogen bond donors, and 29 hydrogen bond acceptors.

Where does this data come from?

All data for 3-amino-N-[2-(3-chloro-4-cyclohexylphenyl)ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[(2S)-2-(2,5-difluoro-4-piperidin-1-ylphenyl)propyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-6-ethyl-5-fluoro-N-[2-(4-piperidin-1-ylphenyl)ethyl]thieno[2,3-b]pyridine-2-carboxamide;3-amino-6-methyl-N-[2-(4-piperidin-1-ylphenyl)ethyl]-4-(trifluoromethyl)thieno[2,3-b]pyridine-2-carboxamide;3-amino-6-methyl-N-[(2R)-2-(4-piperidin-1-ylphenyl)propyl]thieno[2,3-b]pyridine-2-carboxamide;3-amino-6-methyl-N-[(2S)-2-(4-piperidin-1-ylphenyl)propyl]thieno[2,3-b]pyridine-2-carboxamide is sourced from PubChem (CID 157358975), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).