N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-3-cyclopropyl-1-methylpyrazole-5-carboxamide;N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-2,5-dimethylpyrazole-3-carboxamide;N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-3-methyl-1-propan-2-ylpyrazole-4-carboxamide;N-[3-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-4-methylphenyl]-4-(trifluoromethyl)pyridine-2-carboxamide;N-[5-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-6-methyl-3-pyridinyl]-4-(trifluoromethyl)pyridine-2-carboxamide;N-[3-[5-cyano-6-(oxan-4-ylamino)-3-pyridinyl]-4-methylphenyl]-4-(trifluoromethyl)pyridine-2-carboxamide

C139H133F9N34O9 — CID 157366244

IUPACN-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-3-cyclopropyl-1-methylpyrazole-5-carboxamide;N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-2,5-dimethylpyrazole-3-carboxamide;N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-3-methyl-1-propan-2-ylpyrazole-4-carboxamide;N-[3-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-4-methylphenyl]-4-(trifluoromethyl)pyridine-2-carboxamide;N-[5-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-6-methyl-3-pyridinyl]-4-(trifluoromethyl)pyridine-2-carboxamide;N-[3-[5-cyano-6-(oxan-4-ylamino)-3-pyridinyl]-4-methylphenyl]-4-(trifluoromethyl)pyridine-2-carboxamide
SMILESCc1cc(C(=O)Nc2ccc(C)c(-c3cnc(N(C)C)c(C#N)c3)c2)n(C)n1.Cc1ccc(NC(=O)c2cc(C(F)(F)F)ccn2)cc1-c1cnc(N2CC(C)(O)C2)c(C#N)c1.Cc1ccc(NC(=O)c2cc(C(F)(F)F)ccn2)cc1-c1cnc(NC2CCOCC2)c(C#N)c1.Cc1ccc(NC(=O)c2cc(C3CC3)nn2C)cc1-c1cnc(N(C)C)c(C#N)c1.Cc1ccc(NC(=O)c2cn(C(C)C)nc2C)cc1-c1cnc(N(C)C)c(C#N)c1.Cc1ncc(NC(=O)c2cc(C(F)(F)F)ccn2)cc1-c1cnc(N2CC(C)(O)C2)c(C#N)c1
InChIInChI=1S/C25H22F3N5O2.C24H20F3N5O2.C23H19F3N6O2.C23H24N6O.C23H26N6O.C21H22N6O/c1-15-2-3-20(33-24(34)22-11-18(4-7-30-22)25(26,27)28)12-21(15)17-10-16(13-29)23(31-14-17)32-19-5-8-35-9-6-19;1-14-3-4-18(31-22(33)20-8-17(5-6-29-20)24(25,26)27)9-19(14)16-7-15(10-28)21(30-11-16)32-12-23(2,34)13-32;1-13-18(15-5-14(8-27)20(30-9-15)32-11-22(2,34)12-32)7-17(10-29-13)31-21(33)19-6-16(3-4-28-19)23(24,25)26;1-14-5-8-18(26-23(30)21-11-20(15-6-7-15)27-29(21)4)10-19(14)17-9-16(12-24)22(25-13-17)28(2)3;1-14(2)29-13-21(16(4)27-29)23(30)26-19-8-7-15(3)20(10-19)18-9-17(11-24)22(25-12-18)28(5)6;1-13-6-7-17(24-21(28)19-8-14(2)25-27(19)5)10-18(13)16-9-15(11-22)20(23-12-16)26(3)4/h2-4,7,10-12,14,19H,5-6,8-9H2,1H3,(H,31,32)(H,33,34);3-9,11,34H,12-13H2,1-2H3,(H,31,33);3-7,9-10,34H,11-12H2,1-2H3,(H,31,33);5,8-11,13,15H,6-7H2,1-4H3,(H,26,30);7-10,12-14H,1-6H3,(H,26,30);6-10,12H,1-5H3,(H,24,28)
InChIKeyBJFHEVCCCIEZIU-UHFFFAOYSA-N
MW2594.80 g/mol
LogP24.39
Rot. Bonds27

About N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-3-cyclopropyl-1-methylpyrazole-5-carboxamide;N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-2,5-dimethylpyrazole-3-carboxamide;N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-3-methyl-1-propan-2-ylpyrazole-4-carboxamide;N-[3-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-4-methylphenyl]-4-(trifluoromethyl)pyridine-2-carboxamide;N-[5-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-6-methyl-3-pyridinyl]-4-(trifluoromethyl)pyridine-2-carboxamide;N-[3-[5-cyano-6-(oxan-4-ylamino)-3-pyridinyl]-4-methylphenyl]-4-(trifluoromethyl)pyridine-2-carboxamide

N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-3-cyclopropyl-1-methylpyrazole-5-carboxamide;N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-2,5-dimethylpyrazole-3-carboxamide;N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-3-methyl-1-propan-2-ylpyrazole-4-carboxamide;N-[3-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-4-methylphenyl]-4-(trifluoromethyl)pyridine-2-carboxamide;N-[5-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-6-methyl-3-pyridinyl]-4-(trifluoromethyl)pyridine-2-carboxamide;N-[3-[5-cyano-6-(oxan-4-ylamino)-3-pyridinyl]-4-methylphenyl]-4-(trifluoromethyl)pyridine-2-carboxamide (PubChem CID 157366244) has the molecular formula C139H133F9N34O9 and a molecular weight of 2594.80 g/mol. Its IUPAC name is N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-3-cyclopropyl-1-methylpyrazole-5-carboxamide;N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-2,5-dimethylpyrazole-3-carboxamide;N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-3-methyl-1-propan-2-ylpyrazole-4-carboxamide;N-[3-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-4-methylphenyl]-4-(trifluoromethyl)pyridine-2-carboxamide;N-[5-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-6-methyl-3-pyridinyl]-4-(trifluoromethyl)pyridine-2-carboxamide;N-[3-[5-cyano-6-(oxan-4-ylamino)-3-pyridinyl]-4-methylphenyl]-4-(trifluoromethyl)pyridine-2-carboxamide.

Molecular Properties

Compound NameN-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-3-cyclopropyl-1-methylpyrazole-5-carboxamide;N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-2,5-dimethylpyrazole-3-carboxamide;N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-3-methyl-1-propan-2-ylpyrazole-4-carboxamide;N-[3-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-4-methylphenyl]-4-(trifluoromethyl)pyridine-2-carboxamide;N-[5-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-6-methyl-3-pyridinyl]-4-(trifluoromethyl)pyridine-2-carboxamide;N-[3-[5-cyano-6-(oxan-4-ylamino)-3-pyridinyl]-4-methylphenyl]-4-(trifluoromethyl)pyridine-2-carboxamide
PubChem CID157366244
Molecular FormulaC139H133F9N34O9
Molecular Weight2594.80 g/mol
Exact Mass2593.09
IUPAC NameN-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-3-cyclopropyl-1-methylpyrazole-5-carboxamide;N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-2,5-dimethylpyrazole-3-carboxamide;N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-3-methyl-1-propan-2-ylpyrazole-4-carboxamide;N-[3-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-4-methylphenyl]-4-(trifluoromethyl)pyridine-2-carboxamide;N-[5-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-6-methyl-3-pyridinyl]-4-(trifluoromethyl)pyridine-2-carboxamide;N-[3-[5-cyano-6-(oxan-4-ylamino)-3-pyridinyl]-4-methylphenyl]-4-(trifluoromethyl)pyridine-2-carboxamide
SMILESCc1cc(C(=O)Nc2ccc(C)c(-c3cnc(N(C)C)c(C#N)c3)c2)n(C)n1.Cc1ccc(NC(=O)c2cc(C(F)(F)F)ccn2)cc1-c1cnc(N2CC(C)(O)C2)c(C#N)c1.Cc1ccc(NC(=O)c2cc(C(F)(F)F)ccn2)cc1-c1cnc(NC2CCOCC2)c(C#N)c1.Cc1ccc(NC(=O)c2cc(C3CC3)nn2C)cc1-c1cnc(N(C)C)c(C#N)c1.Cc1ccc(NC(=O)c2cn(C(C)C)nc2C)cc1-c1cnc(N(C)C)c(C#N)c1.Cc1ncc(NC(=O)c2cc(C(F)(F)F)ccn2)cc1-c1cnc(N2CC(C)(O)C2)c(C#N)c1
InChIInChI=1S/C25H22F3N5O2.C24H20F3N5O2.C23H19F3N6O2.C23H24N6O.C23H26N6O.C21H22N6O/c1-15-2-3-20(33-24(34)22-11-18(4-7-30-22)25(26,27)28)12-21(15)17-10-16(13-29)23(31-14-17)32-19-5-8-35-9-6-19;1-14-3-4-18(31-22(33)20-8-17(5-6-29-20)24(25,26)27)9-19(14)16-7-15(10-28)21(30-11-16)32-12-23(2,34)13-32;1-13-18(15-5-14(8-27)20(30-9-15)32-11-22(2,34)12-32)7-17(10-29-13)31-21(33)19-6-16(3-4-28-19)23(24,25)26;1-14-5-8-18(26-23(30)21-11-20(15-6-7-15)27-29(21)4)10-19(14)17-9-16(12-24)22(25-13-17)28(2)3;1-14(2)29-13-21(16(4)27-29)23(30)26-19-8-7-15(3)20(10-19)18-9-17(11-24)22(25-12-18)28(5)6;1-13-6-7-17(24-21(28)19-8-14(2)25-27(19)5)10-18(13)16-9-15(11-22)20(23-12-16)26(3)4/h2-4,7,10-12,14,19H,5-6,8-9H2,1H3,(H,31,32)(H,33,34);3-9,11,34H,12-13H2,1-2H3,(H,31,33);3-7,9-10,34H,11-12H2,1-2H3,(H,31,33);5,8-11,13,15H,6-7H2,1-4H3,(H,26,30);7-10,12-14H,1-6H3,(H,26,30);6-10,12H,1-5H3,(H,24,28)
InChIKeyBJFHEVCCCIEZIU-UHFFFAOYSA-N
XLogP24.39
TPSA577.62 Ų
H-Bond Donors9
H-Bond Acceptors37
Rotatable Bonds27
Heavy Atoms191
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5002594.80
LogP ≤ 524.39
H-Bond Donors ≤ 59
H-Bond Acceptors ≤ 1037

Analyze N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-3-cyclopropyl-1-methylpyrazole-5-carboxamide;N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-2,5-dimethylpyrazole-3-carboxamide;N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-3-methyl-1-propan-2-ylpyrazole-4-carboxamide;N-[3-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-4-methylphenyl]-4-(trifluoromethyl)pyridine-2-carboxamide;N-[5-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-6-methyl-3-pyridinyl]-4-(trifluoromethyl)pyridine-2-carboxamide;N-[3-[5-cyano-6-(oxan-4-ylamino)-3-pyridinyl]-4-methylphenyl]-4-(trifluoromethyl)pyridine-2-carboxamide with MolForge

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Launch Full Analysis

Related Compounds

N-[3-[5-cyano-6-(1-methylpyrazol-4-yl)-3-pyridinyl]-4-methylphenyl]-2-(trifluoromethyl)pyridine-4-carboxamide;N-[3-[5-cyano-6-(4-oxo-1-pyridinyl)-3-pyridinyl]-4-methylphenyl]-2-(2-cyanopropan-2-yl)pyridine-4-carboxamide;2-(2-cyanopropan-2-yl)-N-[3-(5-cyano-6-propan-2-yl-3-pyridinyl)-4-methylphenyl]pyridine-4-carboxamide;2-(2-cyanopropan-2-yl)-N-[5-(5-cyano-6-pyridazin-4-yl-3-pyridinyl)-6-methyl-3-pyridinyl]pyridine-4-carboxamide;2-(2-cyanopropan-2-yl)-N-[5-[5-cyano-6-(1,3,5-trimethylpyrazol-4-yl)-3-pyridinyl]-6-methyl-3-pyridinyl]pyridine-4-carboxamide;N-[3-(5-cyano-6-propan-2-yl-3-pyridinyl)-4-methylphenyl]-2-(trifluoromethyl)pyridine-4-carboxamide
CID 157172471
N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-1,3-dimethylpyrazole-4-carboxamide;N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-1-ethyl-3-methylpyrazole-4-carboxamide;N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-1-ethyl-6-oxo-5-(trifluoromethyl)pyridine-3-carboxamide;N-[3-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-4-methylphenyl]-2-ethyl-3-oxo-4-(trifluoromethyl)-2H-pyridine-6-carboxamide;N-[3-(5-cyano-6-morpholin-4-yl-3-pyridinyl)-4-methylphenyl]-4-(trifluoromethyl)pyridine-2-carboxamide;N-[5-(5-cyano-6-morpholin-4-yl-3-pyridinyl)-6-methyl-3-pyridinyl]-4-(trifluoromethyl)pyridine-2-carboxamide
CID 157313884
3-(2-aminopropan-2-yl)-N-[3-[5-cyano-6-(1,3-dimethylpyrazol-4-yl)-3-pyridinyl]-4-methylphenyl]-5-(trifluoromethyl)benzamide;N-[5-[5-cyano-6-(3-hydroxyazetidin-1-yl)-3-pyridinyl]-6-methyl-3-pyridinyl]-3-(trifluoromethyl)benzamide;N-[3-[5-cyano-6-(1-methylpyrazol-4-yl)-3-pyridinyl]-4-methylphenyl]-3-(trifluoromethyl)benzamide;N-[5-[5-cyano-6-(oxan-4-yl)-3-pyridinyl]-6-methyl-3-pyridinyl]-3-(trifluoromethyl)benzamide;N-[3-[5-cyano-6-(4-oxo-1-pyridinyl)-3-pyridinyl]-4-methylphenyl]-3-(trifluoromethyl)benzamide;N-[5-(5-cyano-6-pyridin-4-yl-3-pyridinyl)-6-methyl-3-pyridinyl]-3-(trifluoromethyl)benzamide
CID 157623051
N-[3-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-4-methylphenyl]-6-(2-fluoropropan-2-yl)pyridazine-4-carboxamide;N-[5-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-6-methyl-3-pyridinyl]-6-(2-cyanopropan-2-yl)pyridazine-4-carboxamide;N-[5-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-6-methyl-3-pyridinyl]-6-cyclopropylpyridazine-4-carboxamide;N-[5-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-6-methyl-3-pyridinyl]-6-(trifluoromethyl)pyridazine-4-carboxamide;N-[3-[5-cyano-6-(2-methoxyethylamino)-3-pyridinyl]-4-methylphenyl]-6-(trifluoromethyl)pyridazine-4-carboxamide;N-[5-[5-cyano-6-(oxan-4-yl)-3-pyridinyl]-6-methyl-3-pyridinyl]-6-(trifluoromethyl)pyridazine-4-carboxamide
CID 157641999
N-[5-[5-cyano-6-(1,3-dimethylpyrazol-4-yl)-3-pyridinyl]-6-methyl-3-pyridinyl]-2-(2-cyanopropan-2-yl)pyridine-4-carboxamide;N-[3-[5-cyano-6-(4-oxo-1-pyridinyl)-3-pyridinyl]-4-methylphenyl]-2-(2-cyanopropan-2-yl)pyridine-4-carboxamide;N-[3-[5-cyano-6-(4-oxo-1-pyridinyl)-3-pyridinyl]-4-methylphenyl]-2-(trifluoromethyl)pyridine-4-carboxamide;2-(2-cyanopropan-2-yl)-N-[5-(5-cyano-6-pyridazin-4-yl-3-pyridinyl)-6-methyl-3-pyridinyl]pyridine-4-carboxamide;2-(2-cyanopropan-2-yl)-N-[5-[5-cyano-6-(1,3,5-trimethylpyrazol-4-yl)-3-pyridinyl]-6-methyl-3-pyridinyl]pyridine-4-carboxamide;N-[3-(5-cyano-6-propan-2-yl-3-pyridinyl)-4-methylphenyl]-2-(trifluoromethyl)pyridine-4-carboxamide
CID 157686770
N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-5-cyclopropyl-1,2-oxazole-3-carboxamide;N-[3-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-4-methylphenyl]-4-(trifluoromethyl)pyridine-2-carboxamide;N-[3-(5-cyano-6-morpholin-4-yl-3-pyridinyl)-4-methylphenyl]-6-(2-cyanopropan-2-yl)pyridazine-4-carboxamide;N-[3-(5-cyano-6-morpholin-4-yl-3-pyridinyl)-4-methylphenyl]-6-(2-fluoropropan-2-yl)pyridazine-4-carboxamide;N-[3-(5-cyano-6-morpholin-4-yl-3-pyridinyl)-4-methylphenyl]-6-(trifluoromethyl)pyridazine-4-carboxamide;N-[5-(5-cyano-6-morpholin-4-yl-3-pyridinyl)-6-methyl-3-pyridinyl]-6-(2-cyanopropan-2-yl)pyridazine-4-carboxamide
CID 157699374
N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-1,3-dimethylpyrazole-4-carboxamide;N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-2,5-dimethylpyrazole-3-carboxamide;N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-3-methyl-1-propan-2-ylpyrazole-4-carboxamide;N-[3-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-4-methylphenyl]-4-(trifluoromethyl)pyridine-2-carboxamide;N-[5-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-6-methyl-3-pyridinyl]-4-(trifluoromethyl)pyridine-2-carboxamide;N-[5-(5-cyano-6-morpholin-4-yl-3-pyridinyl)-6-methyl-3-pyridinyl]-5-(trifluoromethyl)pyridine-3-carboxamide
CID 157707307
N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-1,3-dimethylpyrazole-4-carboxamide;N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-1-ethyl-3-methylpyrazole-4-carboxamide;N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-1-ethyl-6-oxo-5-(trifluoromethyl)pyridine-3-carboxamide;N-[3-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-4-methylphenyl]-1-ethyl-6-oxo-5-(trifluoromethyl)pyridine-3-carboxamide;N-[3-(5-cyano-6-morpholin-4-yl-3-pyridinyl)-4-methylphenyl]-4-(trifluoromethyl)pyridine-2-carboxamide;N-[5-(5-cyano-6-morpholin-4-yl-3-pyridinyl)-6-methyl-3-pyridinyl]-4-(trifluoromethyl)pyridine-2-carboxamide
CID 157782406
N-[3-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-4-methylphenyl]-6-(2-cyanopropan-2-yl)pyridazine-4-carboxamide;N-[3-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-4-methylphenyl]-6-(trifluoromethyl)pyridazine-4-carboxamide;N-[3-[5-cyano-6-(2-methoxyethylamino)-3-pyridinyl]-4-methylphenyl]-6-(2-cyanopropan-2-yl)pyridazine-4-carboxamide;N-[5-[5-cyano-6-(2-methoxyethylamino)-3-pyridinyl]-6-methyl-3-pyridinyl]-6-(2-cyanopropan-2-yl)pyridazine-4-carboxamide;N-[5-[5-cyano-6-(oxan-4-ylamino)-3-pyridinyl]-6-methyl-3-pyridinyl]-6-cyclopropylpyridazine-4-carboxamide;N-[3-(5-cyano-6-piperazin-1-yl-3-pyridinyl)-4-methylphenyl]-6-(2-cyanopropan-2-yl)pyridazine-4-carboxamide
CID 157873507
N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-3-cyclopropyl-1-methylpyrazole-5-carboxamide;N-[5-[5-cyano-6-(dimethylamino)-3-pyridinyl]-6-methyl-3-pyridinyl]-5-cyclopropyl-1,2-oxazole-3-carboxamide;N-[3-[5-cyano-6-(oxan-4-ylamino)-3-pyridinyl]-4-methylphenyl]-4-(trifluoromethyl)pyridine-2-carboxamide;N-[5-[5-cyano-6-(oxan-4-ylamino)-3-pyridinyl]-6-methyl-3-pyridinyl]-4-(trifluoromethyl)pyridine-2-carboxamide
CID 158126779
3-(2-aminopropan-2-yl)-N-[5-(5-cyano-6-morpholin-4-yl-3-pyridinyl)-6-methyl-3-pyridinyl]-5-(trifluoromethyl)benzamide;N-[3-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-4-methylphenyl]-3-methylbenzamide;N-[5-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-6-methyl-3-pyridinyl]-3-(difluoromethyl)benzamide;N-[5-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-6-methyl-3-pyridinyl]-3-methylbenzamide;N-[5-[5-cyano-6-(2-methoxyethylamino)-3-pyridinyl]-6-methyl-3-pyridinyl]-3-(difluoromethyl)benzamide;N-[5-[5-cyano-6-(oxan-4-ylamino)-3-pyridinyl]-6-methyl-3-pyridinyl]-3-(difluoromethyl)benzamide
CID 158655694
6-cyclopropyl-N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]pyridazine-4-carboxamide;1,3-dimethyl-N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]pyrazole-4-carboxamide;1-ethyl-3-methyl-N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]pyrazole-4-carboxamide;6-(2-fluoropropan-2-yl)-N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]pyridazine-4-carboxamide;3-methyl-N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-1-propan-2-ylpyrazole-4-carboxamide;N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-4-(trifluoromethyl)pyridine-2-carboxamide
CID 158986888

Frequently Asked Questions

What is the IUPAC name of N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-3-cyclopropyl-1-methylpyrazole-5-carboxamide;N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-2,5-dimethylpyrazole-3-carboxamide;N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-3-methyl-1-propan-2-ylpyrazole-4-carboxamide;N-[3-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-4-methylphenyl]-4-(trifluoromethyl)pyridine-2-carboxamide;N-[5-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-6-methyl-3-pyridinyl]-4-(trifluoromethyl)pyridine-2-carboxamide;N-[3-[5-cyano-6-(oxan-4-ylamino)-3-pyridinyl]-4-methylphenyl]-4-(trifluoromethyl)pyridine-2-carboxamide?
The IUPAC name of N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-3-cyclopropyl-1-methylpyrazole-5-carboxamide;N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-2,5-dimethylpyrazole-3-carboxamide;N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-3-methyl-1-propan-2-ylpyrazole-4-carboxamide;N-[3-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-4-methylphenyl]-4-(trifluoromethyl)pyridine-2-carboxamide;N-[5-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-6-methyl-3-pyridinyl]-4-(trifluoromethyl)pyridine-2-carboxamide;N-[3-[5-cyano-6-(oxan-4-ylamino)-3-pyridinyl]-4-methylphenyl]-4-(trifluoromethyl)pyridine-2-carboxamide (CID 157366244) is N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-3-cyclopropyl-1-methylpyrazole-5-carboxamide;N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-2,5-dimethylpyrazole-3-carboxamide;N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-3-methyl-1-propan-2-ylpyrazole-4-carboxamide;N-[3-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-4-methylphenyl]-4-(trifluoromethyl)pyridine-2-carboxamide;N-[5-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-6-methyl-3-pyridinyl]-4-(trifluoromethyl)pyridine-2-carboxamide;N-[3-[5-cyano-6-(oxan-4-ylamino)-3-pyridinyl]-4-methylphenyl]-4-(trifluoromethyl)pyridine-2-carboxamide.
What is the SMILES notation for N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-3-cyclopropyl-1-methylpyrazole-5-carboxamide;N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-2,5-dimethylpyrazole-3-carboxamide;N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-3-methyl-1-propan-2-ylpyrazole-4-carboxamide;N-[3-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-4-methylphenyl]-4-(trifluoromethyl)pyridine-2-carboxamide;N-[5-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-6-methyl-3-pyridinyl]-4-(trifluoromethyl)pyridine-2-carboxamide;N-[3-[5-cyano-6-(oxan-4-ylamino)-3-pyridinyl]-4-methylphenyl]-4-(trifluoromethyl)pyridine-2-carboxamide?
The canonical SMILES for N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-3-cyclopropyl-1-methylpyrazole-5-carboxamide;N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-2,5-dimethylpyrazole-3-carboxamide;N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-3-methyl-1-propan-2-ylpyrazole-4-carboxamide;N-[3-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-4-methylphenyl]-4-(trifluoromethyl)pyridine-2-carboxamide;N-[5-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-6-methyl-3-pyridinyl]-4-(trifluoromethyl)pyridine-2-carboxamide;N-[3-[5-cyano-6-(oxan-4-ylamino)-3-pyridinyl]-4-methylphenyl]-4-(trifluoromethyl)pyridine-2-carboxamide is Cc1cc(C(=O)Nc2ccc(C)c(-c3cnc(N(C)C)c(C#N)c3)c2)n(C)n1.Cc1ccc(NC(=O)c2cc(C(F)(F)F)ccn2)cc1-c1cnc(N2CC(C)(O)C2)c(C#N)c1.Cc1ccc(NC(=O)c2cc(C(F)(F)F)ccn2)cc1-c1cnc(NC2CCOCC2)c(C#N)c1.Cc1ccc(NC(=O)c2cc(C3CC3)nn2C)cc1-c1cnc(N(C)C)c(C#N)c1.Cc1ccc(NC(=O)c2cn(C(C)C)nc2C)cc1-c1cnc(N(C)C)c(C#N)c1.Cc1ncc(NC(=O)c2cc(C(F)(F)F)ccn2)cc1-c1cnc(N2CC(C)(O)C2)c(C#N)c1.
What is the InChIKey of N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-3-cyclopropyl-1-methylpyrazole-5-carboxamide;N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-2,5-dimethylpyrazole-3-carboxamide;N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-3-methyl-1-propan-2-ylpyrazole-4-carboxamide;N-[3-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-4-methylphenyl]-4-(trifluoromethyl)pyridine-2-carboxamide;N-[5-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-6-methyl-3-pyridinyl]-4-(trifluoromethyl)pyridine-2-carboxamide;N-[3-[5-cyano-6-(oxan-4-ylamino)-3-pyridinyl]-4-methylphenyl]-4-(trifluoromethyl)pyridine-2-carboxamide?
The InChIKey is BJFHEVCCCIEZIU-UHFFFAOYSA-N. The full InChI is InChI=1S/C25H22F3N5O2.C24H20F3N5O2.C23H19F3N6O2.C23H24N6O.C23H26N6O.C21H22N6O/c1-15-2-3-20(33-24(34)22-11-18(4-7-30-22)25(26,27)28)12-21(15)17-10-16(13-29)23(31-14-17)32-19-5-8-35-9-6-19;1-14-3-4-18(31-22(33)20-8-17(5-6-29-20)24(25,26)27)9-19(14)16-7-15(10-28)21(30-11-16)32-12-23(2,34)13-32;1-13-18(15-5-14(8-27)20(30-9-15)32-11-22(2,34)12-32)7-17(10-29-13)31-21(33)19-6-16(3-4-28-19)23(24,25)26;1-14-5-8-18(26-23(30)21-11-20(15-6-7-15)27-29(21)4)10-19(14)17-9-16(12-24)22(25-13-17)28(2)3;1-14(2)29-13-21(16(4)27-29)23(30)26-19-8-7-15(3)20(10-19)18-9-17(11-24)22(25-12-18)28(5)6;1-13-6-7-17(24-21(28)19-8-14(2)25-27(19)5)10-18(13)16-9-15(11-22)20(23-12-16)26(3)4/h2-4,7,10-12,14,19H,5-6,8-9H2,1H3,(H,31,32)(H,33,34);3-9,11,34H,12-13H2,1-2H3,(H,31,33);3-7,9-10,34H,11-12H2,1-2H3,(H,31,33);5,8-11,13,15H,6-7H2,1-4H3,(H,26,30);7-10,12-14H,1-6H3,(H,26,30);6-10,12H,1-5H3,(H,24,28).
What are the key properties of N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-3-cyclopropyl-1-methylpyrazole-5-carboxamide;N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-2,5-dimethylpyrazole-3-carboxamide;N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-3-methyl-1-propan-2-ylpyrazole-4-carboxamide;N-[3-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-4-methylphenyl]-4-(trifluoromethyl)pyridine-2-carboxamide;N-[5-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-6-methyl-3-pyridinyl]-4-(trifluoromethyl)pyridine-2-carboxamide;N-[3-[5-cyano-6-(oxan-4-ylamino)-3-pyridinyl]-4-methylphenyl]-4-(trifluoromethyl)pyridine-2-carboxamide?
N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-3-cyclopropyl-1-methylpyrazole-5-carboxamide;N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-2,5-dimethylpyrazole-3-carboxamide;N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-3-methyl-1-propan-2-ylpyrazole-4-carboxamide;N-[3-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-4-methylphenyl]-4-(trifluoromethyl)pyridine-2-carboxamide;N-[5-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-6-methyl-3-pyridinyl]-4-(trifluoromethyl)pyridine-2-carboxamide;N-[3-[5-cyano-6-(oxan-4-ylamino)-3-pyridinyl]-4-methylphenyl]-4-(trifluoromethyl)pyridine-2-carboxamide has a molecular weight of 2594.80 g/mol, XLogP of 24.39, 27 rotatable bonds, 9 hydrogen bond donors, and 37 hydrogen bond acceptors.
Where does this data come from?
All data for N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-3-cyclopropyl-1-methylpyrazole-5-carboxamide;N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-2,5-dimethylpyrazole-3-carboxamide;N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-3-methyl-1-propan-2-ylpyrazole-4-carboxamide;N-[3-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-4-methylphenyl]-4-(trifluoromethyl)pyridine-2-carboxamide;N-[5-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-6-methyl-3-pyridinyl]-4-(trifluoromethyl)pyridine-2-carboxamide;N-[3-[5-cyano-6-(oxan-4-ylamino)-3-pyridinyl]-4-methylphenyl]-4-(trifluoromethyl)pyridine-2-carboxamide is sourced from PubChem (CID 157366244), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).