5-[7-amino-3-(4-chlorophenyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidine-2-carboxylic acid;5-[7-amino-3-(2-methoxy-4-pyridinyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidine-2-carboxylic acid;5-[7-amino-3-(4-phenoxyphenyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidine-2-carboxylic acid;5-[7-amino-3-(4-phenylphenyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidine-2-carboxylic acid;3-quinolin-3-yl-5-(1,2,3,6-tetrahydropyridin-4-yl)pyrazolo[1,5-a]pyrimidin-7-amine

C104H102ClN27O10 — CID 157377865

About 5-[7-amino-3-(4-chlorophenyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidine-2-carboxylic acid;5-[7-amino-3-(2-methoxy-4-pyridinyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidine-2-carboxylic acid;5-[7-amino-3-(4-phenoxyphenyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidine-2-carboxylic acid;5-[7-amino-3-(4-phenylphenyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidine-2-carboxylic acid;3-quinolin-3-yl-5-(1,2,3,6-tetrahydropyridin-4-yl)pyrazolo[1,5-a]pyrimidin-7-amine

5-[7-amino-3-(4-chlorophenyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidine-2-carboxylic acid;5-[7-amino-3-(2-methoxy-4-pyridinyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidine-2-carboxylic acid;5-[7-amino-3-(4-phenoxyphenyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidine-2-carboxylic acid;5-[7-amino-3-(4-phenylphenyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidine-2-carboxylic acid;3-quinolin-3-yl-5-(1,2,3,6-tetrahydropyridin-4-yl)pyrazolo[1,5-a]pyrimidin-7-amine (PubChem CID 157377865) has the molecular formula C104H102ClN27O10 and a molecular weight of 1925.59 g/mol. Its IUPAC name is 5-[7-amino-3-(4-chlorophenyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidine-2-carboxylic acid;5-[7-amino-3-(2-methoxy-4-pyridinyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidine-2-carboxylic acid;5-[7-amino-3-(4-phenoxyphenyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidine-2-carboxylic acid;5-[7-amino-3-(4-phenylphenyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidine-2-carboxylic acid;3-quinolin-3-yl-5-(1,2,3,6-tetrahydropyridin-4-yl)pyrazolo[1,5-a]pyrimidin-7-amine.

Molecular Properties

• Compound Name: 5-[7-amino-3-(4-chlorophenyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidine-2-carboxylic acid;5-[7-amino-3-(2-methoxy-4-pyridinyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidine-2-carboxylic acid;5-[7-amino-3-(4-phenoxyphenyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidine-2-carboxylic acid;5-[7-amino-3-(4-phenylphenyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidine-2-carboxylic acid;3-quinolin-3-yl-5-(1,2,3,6-tetrahydropyridin-4-yl)pyrazolo[1,5-a]pyrimidin-7-amine
• PubChem CID: 157377865
• Molecular Formula: C104H102ClN27O10
• Molecular Weight: 1925.59 g/mol
• Exact Mass: 1923.80
• IUPAC Name: 5-[7-amino-3-(4-chlorophenyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidine-2-carboxylic acid;5-[7-amino-3-(2-methoxy-4-pyridinyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidine-2-carboxylic acid;5-[7-amino-3-(4-phenoxyphenyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidine-2-carboxylic acid;5-[7-amino-3-(4-phenylphenyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidine-2-carboxylic acid;3-quinolin-3-yl-5-(1,2,3,6-tetrahydropyridin-4-yl)pyrazolo[1,5-a]pyrimidin-7-amine
• SMILES: COc1cc(-c2cnn3c(N)cc(C4CCC(C(=O)O)NC4)nc23)ccn1.Nc1cc(C2=CCNCC2)nc2c(-c3cnc4ccccc4c3)cnn12.Nc1cc(C2CCC(C(=O)O)NC2)nc2c(-c3ccc(-c4ccccc4)cc3)cnn12.Nc1cc(C2CCC(C(=O)O)NC2)nc2c(-c3ccc(Cl)cc3)cnn12.Nc1cc(C2CCC(C(=O)O)NC2)nc2c(-c3ccc(Oc4ccccc4)cc3)cnn12
• InChI: InChI=1S/C24H23N5O3.C24H23N5O2.C20H18N6.C18H18ClN5O2.C18H20N6O3/c25-22-12-21(16-8-11-20(24(30)31)26-13-16)28-23-19(14-27-29(22)23)15-6-9-18(10-7-15)32-17-4-2-1-3-5-17;25-22-12-21(18-10-11-20(24(30)31)26-13-18)28-23-19(14-27-29(22)23)17-8-6-16(7-9-17)15-4-2-1-3-5-15;21-19-10-18(13-5-7-22-8-6-13)25-20-16(12-24-26(19)20)15-9-14-3-1-2-4-17(14)23-11-15;19-12-4-1-10(2-5-12)13-9-22-24-16(20)7-15(23-17(13)24)11-3-6-14(18(25)26)21-8-11;1-27-16-6-10(4-5-20-16)12-9-22-24-15(19)7-14(23-17(12)24)11-2-3-13(18(25)26)21-8-11/h1-7,9-10,12,14,16,20,26H,8,11,13,25H2,(H,30,31);1-9,12,14,18,20,26H,10-11,13,25H2,(H,30,31);1-5,9-12,22H,6-8,21H2;1-2,4-5,7,9,11,14,21H,3,6,8,20H2,(H,25,26);4-7,9,11,13,21H,2-3,8,19H2,1H3,(H,25,26)
• InChIKey: BKNGWQINFQHYEQ-UHFFFAOYSA-N
• XLogP: 14.01
• TPSA: 534.64 Ų
• H-Bond Donors: 14
• H-Bond Acceptors: 33
• Rotatable Bonds: 18
• Heavy Atoms: 142
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	1925.59
LogP ≤ 5	14.01
H-Bond Donors ≤ 5	14
H-Bond Acceptors ≤ 10	33

Frequently Asked Questions

What is the IUPAC name of 5-[7-amino-3-(4-chlorophenyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidine-2-carboxylic acid;5-[7-amino-3-(2-methoxy-4-pyridinyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidine-2-carboxylic acid;5-[7-amino-3-(4-phenoxyphenyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidine-2-carboxylic acid;5-[7-amino-3-(4-phenylphenyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidine-2-carboxylic acid;3-quinolin-3-yl-5-(1,2,3,6-tetrahydropyridin-4-yl)pyrazolo[1,5-a]pyrimidin-7-amine?

The IUPAC name of 5-[7-amino-3-(4-chlorophenyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidine-2-carboxylic acid;5-[7-amino-3-(2-methoxy-4-pyridinyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidine-2-carboxylic acid;5-[7-amino-3-(4-phenoxyphenyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidine-2-carboxylic acid;5-[7-amino-3-(4-phenylphenyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidine-2-carboxylic acid;3-quinolin-3-yl-5-(1,2,3,6-tetrahydropyridin-4-yl)pyrazolo[1,5-a]pyrimidin-7-amine (CID 157377865) is 5-[7-amino-3-(4-chlorophenyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidine-2-carboxylic acid;5-[7-amino-3-(2-methoxy-4-pyridinyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidine-2-carboxylic acid;5-[7-amino-3-(4-phenoxyphenyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidine-2-carboxylic acid;5-[7-amino-3-(4-phenylphenyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidine-2-carboxylic acid;3-quinolin-3-yl-5-(1,2,3,6-tetrahydropyridin-4-yl)pyrazolo[1,5-a]pyrimidin-7-amine.

What is the SMILES notation for 5-[7-amino-3-(4-chlorophenyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidine-2-carboxylic acid;5-[7-amino-3-(2-methoxy-4-pyridinyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidine-2-carboxylic acid;5-[7-amino-3-(4-phenoxyphenyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidine-2-carboxylic acid;5-[7-amino-3-(4-phenylphenyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidine-2-carboxylic acid;3-quinolin-3-yl-5-(1,2,3,6-tetrahydropyridin-4-yl)pyrazolo[1,5-a]pyrimidin-7-amine?

The canonical SMILES for 5-[7-amino-3-(4-chlorophenyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidine-2-carboxylic acid;5-[7-amino-3-(2-methoxy-4-pyridinyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidine-2-carboxylic acid;5-[7-amino-3-(4-phenoxyphenyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidine-2-carboxylic acid;5-[7-amino-3-(4-phenylphenyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidine-2-carboxylic acid;3-quinolin-3-yl-5-(1,2,3,6-tetrahydropyridin-4-yl)pyrazolo[1,5-a]pyrimidin-7-amine is COc1cc(-c2cnn3c(N)cc(C4CCC(C(=O)O)NC4)nc23)ccn1.Nc1cc(C2=CCNCC2)nc2c(-c3cnc4ccccc4c3)cnn12.Nc1cc(C2CCC(C(=O)O)NC2)nc2c(-c3ccc(-c4ccccc4)cc3)cnn12.Nc1cc(C2CCC(C(=O)O)NC2)nc2c(-c3ccc(Cl)cc3)cnn12.Nc1cc(C2CCC(C(=O)O)NC2)nc2c(-c3ccc(Oc4ccccc4)cc3)cnn12.

What is the InChIKey of 5-[7-amino-3-(4-chlorophenyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidine-2-carboxylic acid;5-[7-amino-3-(2-methoxy-4-pyridinyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidine-2-carboxylic acid;5-[7-amino-3-(4-phenoxyphenyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidine-2-carboxylic acid;5-[7-amino-3-(4-phenylphenyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidine-2-carboxylic acid;3-quinolin-3-yl-5-(1,2,3,6-tetrahydropyridin-4-yl)pyrazolo[1,5-a]pyrimidin-7-amine?

The InChIKey is BKNGWQINFQHYEQ-UHFFFAOYSA-N. The full InChI is InChI=1S/C24H23N5O3.C24H23N5O2.C20H18N6.C18H18ClN5O2.C18H20N6O3/c25-22-12-21(16-8-11-20(24(30)31)26-13-16)28-23-19(14-27-29(22)23)15-6-9-18(10-7-15)32-17-4-2-1-3-5-17;25-22-12-21(18-10-11-20(24(30)31)26-13-18)28-23-19(14-27-29(22)23)17-8-6-16(7-9-17)15-4-2-1-3-5-15;21-19-10-18(13-5-7-22-8-6-13)25-20-16(12-24-26(19)20)15-9-14-3-1-2-4-17(14)23-11-15;19-12-4-1-10(2-5-12)13-9-22-24-16(20)7-15(23-17(13)24)11-3-6-14(18(25)26)21-8-11;1-27-16-6-10(4-5-20-16)12-9-22-24-15(19)7-14(23-17(12)24)11-2-3-13(18(25)26)21-8-11/h1-7,9-10,12,14,16,20,26H,8,11,13,25H2,(H,30,31);1-9,12,14,18,20,26H,10-11,13,25H2,(H,30,31);1-5,9-12,22H,6-8,21H2;1-2,4-5,7,9,11,14,21H,3,6,8,20H2,(H,25,26);4-7,9,11,13,21H,2-3,8,19H2,1H3,(H,25,26).

What are the key properties of 5-[7-amino-3-(4-chlorophenyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidine-2-carboxylic acid;5-[7-amino-3-(2-methoxy-4-pyridinyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidine-2-carboxylic acid;5-[7-amino-3-(4-phenoxyphenyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidine-2-carboxylic acid;5-[7-amino-3-(4-phenylphenyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidine-2-carboxylic acid;3-quinolin-3-yl-5-(1,2,3,6-tetrahydropyridin-4-yl)pyrazolo[1,5-a]pyrimidin-7-amine?

5-[7-amino-3-(4-chlorophenyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidine-2-carboxylic acid;5-[7-amino-3-(2-methoxy-4-pyridinyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidine-2-carboxylic acid;5-[7-amino-3-(4-phenoxyphenyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidine-2-carboxylic acid;5-[7-amino-3-(4-phenylphenyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidine-2-carboxylic acid;3-quinolin-3-yl-5-(1,2,3,6-tetrahydropyridin-4-yl)pyrazolo[1,5-a]pyrimidin-7-amine has a molecular weight of 1925.59 g/mol, XLogP of 14.01, 18 rotatable bonds, 14 hydrogen bond donors, and 33 hydrogen bond acceptors.

Where does this data come from?

All data for 5-[7-amino-3-(4-chlorophenyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidine-2-carboxylic acid;5-[7-amino-3-(2-methoxy-4-pyridinyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidine-2-carboxylic acid;5-[7-amino-3-(4-phenoxyphenyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidine-2-carboxylic acid;5-[7-amino-3-(4-phenylphenyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidine-2-carboxylic acid;3-quinolin-3-yl-5-(1,2,3,6-tetrahydropyridin-4-yl)pyrazolo[1,5-a]pyrimidin-7-amine is sourced from PubChem (CID 157377865), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).