N-[5-(1,3-benzodioxol-5-yl)pyrazin-2-yl]-2,6-difluorobenzamide;N-[5-(6-chloro-2,2-difluoro-1,3-benzodioxol-5-yl)pyrazin-2-yl]-4-methyl-1,2-thiazole-5-carboxamide;N-[5-(6-chloro-2,2-difluoro-1,3-benzodioxol-5-yl)-2-pyridinyl]-6-(1,1-difluoroethyl)pyridine-3-carboxamide;N-[5-(6-chloro-2,2-difluoro-1,3-benzodioxol-5-yl)-2-pyridinyl]-3-methylbenzamide;N-[5-(6-chloro-2,2-difluoro-1,3-benzodioxol-5-yl)-2-pyridinyl]-5-methylpyridine-3-carboxamide;N-[5-(6-chloro-2,2-difluoro-1,3-benzodioxol-5-yl)-2-pyridinyl]-6-methylpyridine-3-carboxamide

C112H69Cl5F14N18O18S — CID 157396856

About N-[5-(1,3-benzodioxol-5-yl)pyrazin-2-yl]-2,6-difluorobenzamide;N-[5-(6-chloro-2,2-difluoro-1,3-benzodioxol-5-yl)pyrazin-2-yl]-4-methyl-1,2-thiazole-5-carboxamide;N-[5-(6-chloro-2,2-difluoro-1,3-benzodioxol-5-yl)-2-pyridinyl]-6-(1,1-difluoroethyl)pyridine-3-carboxamide;N-[5-(6-chloro-2,2-difluoro-1,3-benzodioxol-5-yl)-2-pyridinyl]-3-methylbenzamide;N-[5-(6-chloro-2,2-difluoro-1,3-benzodioxol-5-yl)-2-pyridinyl]-5-methylpyridine-3-carboxamide;N-[5-(6-chloro-2,2-difluoro-1,3-benzodioxol-5-yl)-2-pyridinyl]-6-methylpyridine-3-carboxamide

N-[5-(1,3-benzodioxol-5-yl)pyrazin-2-yl]-2,6-difluorobenzamide;N-[5-(6-chloro-2,2-difluoro-1,3-benzodioxol-5-yl)pyrazin-2-yl]-4-methyl-1,2-thiazole-5-carboxamide;N-[5-(6-chloro-2,2-difluoro-1,3-benzodioxol-5-yl)-2-pyridinyl]-6-(1,1-difluoroethyl)pyridine-3-carboxamide;N-[5-(6-chloro-2,2-difluoro-1,3-benzodioxol-5-yl)-2-pyridinyl]-3-methylbenzamide;N-[5-(6-chloro-2,2-difluoro-1,3-benzodioxol-5-yl)-2-pyridinyl]-5-methylpyridine-3-carboxamide;N-[5-(6-chloro-2,2-difluoro-1,3-benzodioxol-5-yl)-2-pyridinyl]-6-methylpyridine-3-carboxamide (PubChem CID 157396856) has the molecular formula C112H69Cl5F14N18O18S and a molecular weight of 2430.20 g/mol. Its IUPAC name is N-[5-(1,3-benzodioxol-5-yl)pyrazin-2-yl]-2,6-difluorobenzamide;N-[5-(6-chloro-2,2-difluoro-1,3-benzodioxol-5-yl)pyrazin-2-yl]-4-methyl-1,2-thiazole-5-carboxamide;N-[5-(6-chloro-2,2-difluoro-1,3-benzodioxol-5-yl)-2-pyridinyl]-6-(1,1-difluoroethyl)pyridine-3-carboxamide;N-[5-(6-chloro-2,2-difluoro-1,3-benzodioxol-5-yl)-2-pyridinyl]-3-methylbenzamide;N-[5-(6-chloro-2,2-difluoro-1,3-benzodioxol-5-yl)-2-pyridinyl]-5-methylpyridine-3-carboxamide;N-[5-(6-chloro-2,2-difluoro-1,3-benzodioxol-5-yl)-2-pyridinyl]-6-methylpyridine-3-carboxamide.

Molecular Properties

• Compound Name: N-[5-(1,3-benzodioxol-5-yl)pyrazin-2-yl]-2,6-difluorobenzamide;N-[5-(6-chloro-2,2-difluoro-1,3-benzodioxol-5-yl)pyrazin-2-yl]-4-methyl-1,2-thiazole-5-carboxamide;N-[5-(6-chloro-2,2-difluoro-1,3-benzodioxol-5-yl)-2-pyridinyl]-6-(1,1-difluoroethyl)pyridine-3-carboxamide;N-[5-(6-chloro-2,2-difluoro-1,3-benzodioxol-5-yl)-2-pyridinyl]-3-methylbenzamide;N-[5-(6-chloro-2,2-difluoro-1,3-benzodioxol-5-yl)-2-pyridinyl]-5-methylpyridine-3-carboxamide;N-[5-(6-chloro-2,2-difluoro-1,3-benzodioxol-5-yl)-2-pyridinyl]-6-methylpyridine-3-carboxamide
• PubChem CID: 157396856
• Molecular Formula: C112H69Cl5F14N18O18S
• Molecular Weight: 2430.20 g/mol
• Exact Mass: 2426.30
• IUPAC Name: N-[5-(1,3-benzodioxol-5-yl)pyrazin-2-yl]-2,6-difluorobenzamide;N-[5-(6-chloro-2,2-difluoro-1,3-benzodioxol-5-yl)pyrazin-2-yl]-4-methyl-1,2-thiazole-5-carboxamide;N-[5-(6-chloro-2,2-difluoro-1,3-benzodioxol-5-yl)-2-pyridinyl]-6-(1,1-difluoroethyl)pyridine-3-carboxamide;N-[5-(6-chloro-2,2-difluoro-1,3-benzodioxol-5-yl)-2-pyridinyl]-3-methylbenzamide;N-[5-(6-chloro-2,2-difluoro-1,3-benzodioxol-5-yl)-2-pyridinyl]-5-methylpyridine-3-carboxamide;N-[5-(6-chloro-2,2-difluoro-1,3-benzodioxol-5-yl)-2-pyridinyl]-6-methylpyridine-3-carboxamide
• SMILES: CC(F)(F)c1ccc(C(=O)Nc2ccc(-c3cc4c(cc3Cl)OC(F)(F)O4)cn2)cn1.Cc1ccc(C(=O)Nc2ccc(-c3cc4c(cc3Cl)OC(F)(F)O4)cn2)cn1.Cc1cccc(C(=O)Nc2ccc(-c3cc4c(cc3Cl)OC(F)(F)O4)cn2)c1.Cc1cncc(C(=O)Nc2ccc(-c3cc4c(cc3Cl)OC(F)(F)O4)cn2)c1.Cc1cnsc1C(=O)Nc1cnc(-c2cc3c(cc2Cl)OC(F)(F)O3)cn1.O=C(Nc1cnc(-c2ccc3c(c2)OCO3)cn1)c1c(F)cccc1F
• InChI: InChI=1S/C20H12ClF4N3O3.C20H13ClF2N2O3.2C19H12ClF2N3O3.C18H11F2N3O3.C16H9ClF2N4O3S/c1-19(22,23)16-4-2-11(9-26-16)18(29)28-17-5-3-10(8-27-17)12-6-14-15(7-13(12)21)31-20(24,25)30-14;1-11-3-2-4-12(7-11)19(26)25-18-6-5-13(10-24-18)14-8-16-17(9-15(14)21)28-20(22,23)27-16;1-10-4-12(8-23-7-10)18(26)25-17-3-2-11(9-24-17)13-5-15-16(6-14(13)20)28-19(21,22)27-15;1-10-2-3-12(9-23-10)18(26)25-17-5-4-11(8-24-17)13-6-15-16(7-14(13)20)28-19(21,22)27-15;19-11-2-1-3-12(20)17(11)18(24)23-16-8-21-13(7-22-16)10-4-5-14-15(6-10)26-9-25-14;1-7-4-22-27-14(7)15(24)23-13-6-20-10(5-21-13)8-2-11-12(3-9(8)17)26-16(18,19)25-11/h2-9H,1H3,(H,27,28,29);2-10H,1H3,(H,24,25,26);2*2-9H,1H3,(H,24,25,26);1-8H,9H2,(H,22,23,24);2-6H,1H3,(H,21,23,24)
• InChIKey: BMRDGHYLUQDIOG-UHFFFAOYSA-N
• XLogP: 27.66
• TPSA: 440.04 Ų
• H-Bond Donors: 6
• H-Bond Acceptors: 31
• Rotatable Bonds: 19
• Heavy Atoms: 168
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2430.20
LogP ≤ 5	27.66
H-Bond Donors ≤ 5	6
H-Bond Acceptors ≤ 10	31

Frequently Asked Questions

What is the IUPAC name of N-[5-(1,3-benzodioxol-5-yl)pyrazin-2-yl]-2,6-difluorobenzamide;N-[5-(6-chloro-2,2-difluoro-1,3-benzodioxol-5-yl)pyrazin-2-yl]-4-methyl-1,2-thiazole-5-carboxamide;N-[5-(6-chloro-2,2-difluoro-1,3-benzodioxol-5-yl)-2-pyridinyl]-6-(1,1-difluoroethyl)pyridine-3-carboxamide;N-[5-(6-chloro-2,2-difluoro-1,3-benzodioxol-5-yl)-2-pyridinyl]-3-methylbenzamide;N-[5-(6-chloro-2,2-difluoro-1,3-benzodioxol-5-yl)-2-pyridinyl]-5-methylpyridine-3-carboxamide;N-[5-(6-chloro-2,2-difluoro-1,3-benzodioxol-5-yl)-2-pyridinyl]-6-methylpyridine-3-carboxamide?

The IUPAC name of N-[5-(1,3-benzodioxol-5-yl)pyrazin-2-yl]-2,6-difluorobenzamide;N-[5-(6-chloro-2,2-difluoro-1,3-benzodioxol-5-yl)pyrazin-2-yl]-4-methyl-1,2-thiazole-5-carboxamide;N-[5-(6-chloro-2,2-difluoro-1,3-benzodioxol-5-yl)-2-pyridinyl]-6-(1,1-difluoroethyl)pyridine-3-carboxamide;N-[5-(6-chloro-2,2-difluoro-1,3-benzodioxol-5-yl)-2-pyridinyl]-3-methylbenzamide;N-[5-(6-chloro-2,2-difluoro-1,3-benzodioxol-5-yl)-2-pyridinyl]-5-methylpyridine-3-carboxamide;N-[5-(6-chloro-2,2-difluoro-1,3-benzodioxol-5-yl)-2-pyridinyl]-6-methylpyridine-3-carboxamide (CID 157396856) is N-[5-(1,3-benzodioxol-5-yl)pyrazin-2-yl]-2,6-difluorobenzamide;N-[5-(6-chloro-2,2-difluoro-1,3-benzodioxol-5-yl)pyrazin-2-yl]-4-methyl-1,2-thiazole-5-carboxamide;N-[5-(6-chloro-2,2-difluoro-1,3-benzodioxol-5-yl)-2-pyridinyl]-6-(1,1-difluoroethyl)pyridine-3-carboxamide;N-[5-(6-chloro-2,2-difluoro-1,3-benzodioxol-5-yl)-2-pyridinyl]-3-methylbenzamide;N-[5-(6-chloro-2,2-difluoro-1,3-benzodioxol-5-yl)-2-pyridinyl]-5-methylpyridine-3-carboxamide;N-[5-(6-chloro-2,2-difluoro-1,3-benzodioxol-5-yl)-2-pyridinyl]-6-methylpyridine-3-carboxamide.

What is the SMILES notation for N-[5-(1,3-benzodioxol-5-yl)pyrazin-2-yl]-2,6-difluorobenzamide;N-[5-(6-chloro-2,2-difluoro-1,3-benzodioxol-5-yl)pyrazin-2-yl]-4-methyl-1,2-thiazole-5-carboxamide;N-[5-(6-chloro-2,2-difluoro-1,3-benzodioxol-5-yl)-2-pyridinyl]-6-(1,1-difluoroethyl)pyridine-3-carboxamide;N-[5-(6-chloro-2,2-difluoro-1,3-benzodioxol-5-yl)-2-pyridinyl]-3-methylbenzamide;N-[5-(6-chloro-2,2-difluoro-1,3-benzodioxol-5-yl)-2-pyridinyl]-5-methylpyridine-3-carboxamide;N-[5-(6-chloro-2,2-difluoro-1,3-benzodioxol-5-yl)-2-pyridinyl]-6-methylpyridine-3-carboxamide?

The canonical SMILES for N-[5-(1,3-benzodioxol-5-yl)pyrazin-2-yl]-2,6-difluorobenzamide;N-[5-(6-chloro-2,2-difluoro-1,3-benzodioxol-5-yl)pyrazin-2-yl]-4-methyl-1,2-thiazole-5-carboxamide;N-[5-(6-chloro-2,2-difluoro-1,3-benzodioxol-5-yl)-2-pyridinyl]-6-(1,1-difluoroethyl)pyridine-3-carboxamide;N-[5-(6-chloro-2,2-difluoro-1,3-benzodioxol-5-yl)-2-pyridinyl]-3-methylbenzamide;N-[5-(6-chloro-2,2-difluoro-1,3-benzodioxol-5-yl)-2-pyridinyl]-5-methylpyridine-3-carboxamide;N-[5-(6-chloro-2,2-difluoro-1,3-benzodioxol-5-yl)-2-pyridinyl]-6-methylpyridine-3-carboxamide is CC(F)(F)c1ccc(C(=O)Nc2ccc(-c3cc4c(cc3Cl)OC(F)(F)O4)cn2)cn1.Cc1ccc(C(=O)Nc2ccc(-c3cc4c(cc3Cl)OC(F)(F)O4)cn2)cn1.Cc1cccc(C(=O)Nc2ccc(-c3cc4c(cc3Cl)OC(F)(F)O4)cn2)c1.Cc1cncc(C(=O)Nc2ccc(-c3cc4c(cc3Cl)OC(F)(F)O4)cn2)c1.Cc1cnsc1C(=O)Nc1cnc(-c2cc3c(cc2Cl)OC(F)(F)O3)cn1.O=C(Nc1cnc(-c2ccc3c(c2)OCO3)cn1)c1c(F)cccc1F.

What is the InChIKey of N-[5-(1,3-benzodioxol-5-yl)pyrazin-2-yl]-2,6-difluorobenzamide;N-[5-(6-chloro-2,2-difluoro-1,3-benzodioxol-5-yl)pyrazin-2-yl]-4-methyl-1,2-thiazole-5-carboxamide;N-[5-(6-chloro-2,2-difluoro-1,3-benzodioxol-5-yl)-2-pyridinyl]-6-(1,1-difluoroethyl)pyridine-3-carboxamide;N-[5-(6-chloro-2,2-difluoro-1,3-benzodioxol-5-yl)-2-pyridinyl]-3-methylbenzamide;N-[5-(6-chloro-2,2-difluoro-1,3-benzodioxol-5-yl)-2-pyridinyl]-5-methylpyridine-3-carboxamide;N-[5-(6-chloro-2,2-difluoro-1,3-benzodioxol-5-yl)-2-pyridinyl]-6-methylpyridine-3-carboxamide?

The InChIKey is BMRDGHYLUQDIOG-UHFFFAOYSA-N. The full InChI is InChI=1S/C20H12ClF4N3O3.C20H13ClF2N2O3.2C19H12ClF2N3O3.C18H11F2N3O3.C16H9ClF2N4O3S/c1-19(22,23)16-4-2-11(9-26-16)18(29)28-17-5-3-10(8-27-17)12-6-14-15(7-13(12)21)31-20(24,25)30-14;1-11-3-2-4-12(7-11)19(26)25-18-6-5-13(10-24-18)14-8-16-17(9-15(14)21)28-20(22,23)27-16;1-10-4-12(8-23-7-10)18(26)25-17-3-2-11(9-24-17)13-5-15-16(6-14(13)20)28-19(21,22)27-15;1-10-2-3-12(9-23-10)18(26)25-17-5-4-11(8-24-17)13-6-15-16(7-14(13)20)28-19(21,22)27-15;19-11-2-1-3-12(20)17(11)18(24)23-16-8-21-13(7-22-16)10-4-5-14-15(6-10)26-9-25-14;1-7-4-22-27-14(7)15(24)23-13-6-20-10(5-21-13)8-2-11-12(3-9(8)17)26-16(18,19)25-11/h2-9H,1H3,(H,27,28,29);2-10H,1H3,(H,24,25,26);2*2-9H,1H3,(H,24,25,26);1-8H,9H2,(H,22,23,24);2-6H,1H3,(H,21,23,24).

What are the key properties of N-[5-(1,3-benzodioxol-5-yl)pyrazin-2-yl]-2,6-difluorobenzamide;N-[5-(6-chloro-2,2-difluoro-1,3-benzodioxol-5-yl)pyrazin-2-yl]-4-methyl-1,2-thiazole-5-carboxamide;N-[5-(6-chloro-2,2-difluoro-1,3-benzodioxol-5-yl)-2-pyridinyl]-6-(1,1-difluoroethyl)pyridine-3-carboxamide;N-[5-(6-chloro-2,2-difluoro-1,3-benzodioxol-5-yl)-2-pyridinyl]-3-methylbenzamide;N-[5-(6-chloro-2,2-difluoro-1,3-benzodioxol-5-yl)-2-pyridinyl]-5-methylpyridine-3-carboxamide;N-[5-(6-chloro-2,2-difluoro-1,3-benzodioxol-5-yl)-2-pyridinyl]-6-methylpyridine-3-carboxamide?

N-[5-(1,3-benzodioxol-5-yl)pyrazin-2-yl]-2,6-difluorobenzamide;N-[5-(6-chloro-2,2-difluoro-1,3-benzodioxol-5-yl)pyrazin-2-yl]-4-methyl-1,2-thiazole-5-carboxamide;N-[5-(6-chloro-2,2-difluoro-1,3-benzodioxol-5-yl)-2-pyridinyl]-6-(1,1-difluoroethyl)pyridine-3-carboxamide;N-[5-(6-chloro-2,2-difluoro-1,3-benzodioxol-5-yl)-2-pyridinyl]-3-methylbenzamide;N-[5-(6-chloro-2,2-difluoro-1,3-benzodioxol-5-yl)-2-pyridinyl]-5-methylpyridine-3-carboxamide;N-[5-(6-chloro-2,2-difluoro-1,3-benzodioxol-5-yl)-2-pyridinyl]-6-methylpyridine-3-carboxamide has a molecular weight of 2430.20 g/mol, XLogP of 27.66, 19 rotatable bonds, 6 hydrogen bond donors, and 31 hydrogen bond acceptors.

Where does this data come from?

All data for N-[5-(1,3-benzodioxol-5-yl)pyrazin-2-yl]-2,6-difluorobenzamide;N-[5-(6-chloro-2,2-difluoro-1,3-benzodioxol-5-yl)pyrazin-2-yl]-4-methyl-1,2-thiazole-5-carboxamide;N-[5-(6-chloro-2,2-difluoro-1,3-benzodioxol-5-yl)-2-pyridinyl]-6-(1,1-difluoroethyl)pyridine-3-carboxamide;N-[5-(6-chloro-2,2-difluoro-1,3-benzodioxol-5-yl)-2-pyridinyl]-3-methylbenzamide;N-[5-(6-chloro-2,2-difluoro-1,3-benzodioxol-5-yl)-2-pyridinyl]-5-methylpyridine-3-carboxamide;N-[5-(6-chloro-2,2-difluoro-1,3-benzodioxol-5-yl)-2-pyridinyl]-6-methylpyridine-3-carboxamide is sourced from PubChem (CID 157396856), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).