3-cyclobutyloxy-N-[6-[5-(hydroxymethyl)-1-methylpyrazol-4-yl]isoquinolin-3-yl]benzamide;4-(1-fluoroethoxy)-N-[6-[1-methyl-5-(piperidin-1-ylmethyl)pyrazol-4-yl]isoquinolin-3-yl]benzamide;N-[6-[5-(hydroxymethyl)-1-methylpyrazol-4-yl]isoquinolin-3-yl]-2-methyl-1,3-dihydroisoindole-5-carboxamide;N-[6-[5-(hydroxymethyl)-1-methylpyrazol-4-yl]isoquinolin-3-yl]-2-methyl-3,4-dihydro-1H-isoquinoline-6-carboxamide;N-[6-[5-(hydroxymethyl)-1-methylpyrazol-4-yl]isoquinolin-3-yl]-2-(1-methylpiperidin-4-yl)sulfanylpyridine-4-carboxamide;N-[6-[5-(hydroxymethyl)-1-methylpyrazol-4-yl]isoquinolin-3-yl]-2-(1-propan-2-ylpiperidin-4-yl)oxypyridine-4-carboxamide;N-[6-[5-(hydroxymethyl)-1-methylpyrazol-4-yl]isoquinolin-3-yl]-5,6,7,8-tetrahydronaphthalene-2-carboxamide;2-(7-methyl-2,7-diazaspiro[3.5]nonan-2-yl)-N-[6-[1-methyl-5-(piperidin-1-ylmethyl)pyrazol-4-yl]isoquinolin-3-yl]pyridine-4-carboxamide;4-methyl-N-[6-[1-methyl-5-(morpholin-4-ylmethyl)pyrazol-4-yl]isoquinolin-3-yl]benzamide;4-methyl-N-[6-[1-methyl-5-(piperidin-1-ylmethyl)pyrazol-4-yl]isoquinolin-3-yl]benzamide;4-methyl-N-[6-[1-methyl-5-(pyrrolidin-1-ylmethyl)pyrazol-4-yl]isoquinolin-3-yl]benzamide;N-[6-[1-methyl-5-(piperidin-1-ylmethyl)pyrazol-4-yl]isoquinolin-3-yl]-3-(pyrrolidin-1-ylmethyl)benzamide

C324H345FN64O22S — CID 157399272

IUPAC3-cyclobutyloxy-N-[6-[5-(hydroxymethyl)-1-methylpyrazol-4-yl]isoquinolin-3-yl]benzamide;4-(1-fluoroethoxy)-N-[6-[1-methyl-5-(piperidin-1-ylmethyl)pyrazol-4-yl]isoquinolin-3-yl]benzamide;N-[6-[5-(hydroxymethyl)-1-methylpyrazol-4-yl]isoquinolin-3-yl]-2-methyl-1,3-dihydroisoindole-5-carboxamide;N-[6-[5-(hydroxymethyl)-1-methylpyrazol-4-yl]isoquinolin-3-yl]-2-methyl-3,4-dihydro-1H-isoquinoline-6-carboxamide;N-[6-[5-(hydroxymethyl)-1-methylpyrazol-4-yl]isoquinolin-3-yl]-2-(1-methylpiperidin-4-yl)sulfanylpyridine-4-carboxamide;N-[6-[5-(hydroxymethyl)-1-methylpyrazol-4-yl]isoquinolin-3-yl]-2-(1-propan-2-ylpiperidin-4-yl)oxypyridine-4-carboxamide;N-[6-[5-(hydroxymethyl)-1-methylpyrazol-4-yl]isoquinolin-3-yl]-5,6,7,8-tetrahydronaphthalene-2-carboxamide;2-(7-methyl-2,7-diazaspiro[3.5]nonan-2-yl)-N-[6-[1-methyl-5-(piperidin-1-ylmethyl)pyrazol-4-yl]isoquinolin-3-yl]pyridine-4-carboxamide;4-methyl-N-[6-[1-methyl-5-(morpholin-4-ylmethyl)pyrazol-4-yl]isoquinolin-3-yl]benzamide;4-methyl-N-[6-[1-methyl-5-(piperidin-1-ylmethyl)pyrazol-4-yl]isoquinolin-3-yl]benzamide;4-methyl-N-[6-[1-methyl-5-(pyrrolidin-1-ylmethyl)pyrazol-4-yl]isoquinolin-3-yl]benzamide;N-[6-[1-methyl-5-(piperidin-1-ylmethyl)pyrazol-4-yl]isoquinolin-3-yl]-3-(pyrrolidin-1-ylmethyl)benzamide
SMILESCC(C)N1CCC(Oc2cc(C(=O)Nc3cc4cc(-c5cnn(C)c5CO)ccc4cn3)ccn2)CC1.CC(F)Oc1ccc(C(=O)Nc2cc3cc(-c4cnn(C)c4CN4CCCCC4)ccc3cn2)cc1.CN1CCC(Sc2cc(C(=O)Nc3cc4cc(-c5cnn(C)c5CO)ccc4cn3)ccn2)CC1.CN1CCC2(CC1)CN(c1cc(C(=O)Nc3cc4cc(-c5cnn(C)c5CN5CCCCC5)ccc4cn3)ccn1)C2.CN1CCc2cc(C(=O)Nc3cc4cc(-c5cnn(C)c5CO)ccc4cn3)ccc2C1.CN1Cc2ccc(C(=O)Nc3cc4cc(-c5cnn(C)c5CO)ccc4cn3)cc2C1.Cc1ccc(C(=O)Nc2cc3cc(-c4cnn(C)c4CN4CCCC4)ccc3cn2)cc1.Cc1ccc(C(=O)Nc2cc3cc(-c4cnn(C)c4CN4CCCCC4)ccc3cn2)cc1.Cc1ccc(C(=O)Nc2cc3cc(-c4cnn(C)c4CN4CCOCC4)ccc3cn2)cc1.Cn1ncc(-c2ccc3cnc(NC(=O)c4ccc5c(c4)CCCC5)cc3c2)c1CO.Cn1ncc(-c2ccc3cnc(NC(=O)c4cccc(CN5CCCC5)c4)cc3c2)c1CN1CCCCC1.Cn1ncc(-c2ccc3cnc(NC(=O)c4cccc(OC5CCC5)c4)cc3c2)c1CO
InChIInChI=1S/C33H40N8O.C31H36N6O.C28H30FN5O2.C28H32N6O3.C27H29N5O.C26H28N6O2S.C26H27N5O2.C26H27N5O.C25H25N5O2.C25H24N4O3.C25H24N4O2.C24H23N5O2/c1-38-14-9-33(10-15-38)22-41(23-33)31-18-25(8-11-34-31)32(42)37-30-17-27-16-24(6-7-26(27)19-35-30)28-20-36-39(2)29(28)21-40-12-4-3-5-13-40;1-35-29(22-37-12-3-2-4-13-37)28(20-33-35)24-10-11-26-19-32-30(18-27(26)17-24)34-31(38)25-9-7-8-23(16-25)21-36-14-5-6-15-36;1-19(29)36-24-10-8-20(9-11-24)28(35)32-27-15-23-14-21(6-7-22(23)16-30-27)25-17-31-33(2)26(25)18-34-12-4-3-5-13-34;1-18(2)34-10-7-23(8-11-34)37-27-14-20(6-9-29-27)28(36)32-26-13-22-12-19(4-5-21(22)15-30-26)24-16-31-33(3)25(24)17-35;1-19-6-8-20(9-7-19)27(33)30-26-15-23-14-21(10-11-22(23)16-28-26)24-17-29-31(2)25(24)18-32-12-4-3-5-13-32;1-31-9-6-21(7-10-31)35-25-13-18(5-8-27-25)26(34)30-24-12-20-11-17(3-4-19(20)14-28-24)22-15-29-32(2)23(22)16-33;1-18-3-5-19(6-4-18)26(32)29-25-14-22-13-20(7-8-21(22)15-27-25)23-16-28-30(2)24(23)17-31-9-11-33-12-10-31;1-18-5-7-19(8-6-18)26(32)29-25-14-22-13-20(9-10-21(22)15-27-25)23-16-28-30(2)24(23)17-31-11-3-4-12-31;1-29-8-7-16-9-18(4-6-20(16)14-29)25(32)28-24-11-21-10-17(3-5-19(21)12-26-24)22-13-27-30(2)23(22)15-31;1-29-23(15-30)22(14-27-29)16-8-9-18-13-26-24(12-19(18)10-16)28-25(31)17-4-2-7-21(11-17)32-20-5-3-6-20;1-29-23(15-30)22(14-27-29)18-7-9-20-13-26-24(12-21(20)11-18)28-25(31)19-8-6-16-4-2-3-5-17(16)10-19;1-28-12-18-6-4-16(8-20(18)13-28)24(31)27-23-9-19-7-15(3-5-17(19)10-25-23)21-11-26-29(2)22(21)14-30/h6-8,11,16-20H,3-5,9-10,12-15,21-23H2,1-2H3,(H,35,37,42);7-11,16-20H,2-6,12-15,21-22H2,1H3,(H,32,34,38);6-11,14-17,19H,3-5,12-13,18H2,1-2H3,(H,30,32,35);4-6,9,12-16,18,23,35H,7-8,10-11,17H2,1-3H3,(H,30,32,36);6-11,14-17H,3-5,12-13,18H2,1-2H3,(H,28,30,33);3-5,8,11-15,21,33H,6-7,9-10,16H2,1-2H3,(H,28,30,34);3-8,13-16H,9-12,17H2,1-2H3,(H,27,29,32);5-10,13-16H,3-4,11-12,17H2,1-2H3,(H,27,29,32);3-6,9-13,31H,7-8,14-15H2,1-2H3,(H,26,28,32);2,4,7-14,20,30H,3,5-6,15H2,1H3,(H,26,28,31);6-14,30H,2-5,15H2,1H3,(H,26,28,31);3-11,30H,12-14H2,1-2H3,(H,25,27,31)
InChIKeyBMYHUXRHFTYHQV-UHFFFAOYSA-N
MW5538.82 g/mol
LogP53.09
Rot. Bonds66

About 3-cyclobutyloxy-N-[6-[5-(hydroxymethyl)-1-methylpyrazol-4-yl]isoquinolin-3-yl]benzamide;4-(1-fluoroethoxy)-N-[6-[1-methyl-5-(piperidin-1-ylmethyl)pyrazol-4-yl]isoquinolin-3-yl]benzamide;N-[6-[5-(hydroxymethyl)-1-methylpyrazol-4-yl]isoquinolin-3-yl]-2-methyl-1,3-dihydroisoindole-5-carboxamide;N-[6-[5-(hydroxymethyl)-1-methylpyrazol-4-yl]isoquinolin-3-yl]-2-methyl-3,4-dihydro-1H-isoquinoline-6-carboxamide;N-[6-[5-(hydroxymethyl)-1-methylpyrazol-4-yl]isoquinolin-3-yl]-2-(1-methylpiperidin-4-yl)sulfanylpyridine-4-carboxamide;N-[6-[5-(hydroxymethyl)-1-methylpyrazol-4-yl]isoquinolin-3-yl]-2-(1-propan-2-ylpiperidin-4-yl)oxypyridine-4-carboxamide;N-[6-[5-(hydroxymethyl)-1-methylpyrazol-4-yl]isoquinolin-3-yl]-5,6,7,8-tetrahydronaphthalene-2-carboxamide;2-(7-methyl-2,7-diazaspiro[3.5]nonan-2-yl)-N-[6-[1-methyl-5-(piperidin-1-ylmethyl)pyrazol-4-yl]isoquinolin-3-yl]pyridine-4-carboxamide;4-methyl-N-[6-[1-methyl-5-(morpholin-4-ylmethyl)pyrazol-4-yl]isoquinolin-3-yl]benzamide;4-methyl-N-[6-[1-methyl-5-(piperidin-1-ylmethyl)pyrazol-4-yl]isoquinolin-3-yl]benzamide;4-methyl-N-[6-[1-methyl-5-(pyrrolidin-1-ylmethyl)pyrazol-4-yl]isoquinolin-3-yl]benzamide;N-[6-[1-methyl-5-(piperidin-1-ylmethyl)pyrazol-4-yl]isoquinolin-3-yl]-3-(pyrrolidin-1-ylmethyl)benzamide

3-cyclobutyloxy-N-[6-[5-(hydroxymethyl)-1-methylpyrazol-4-yl]isoquinolin-3-yl]benzamide;4-(1-fluoroethoxy)-N-[6-[1-methyl-5-(piperidin-1-ylmethyl)pyrazol-4-yl]isoquinolin-3-yl]benzamide;N-[6-[5-(hydroxymethyl)-1-methylpyrazol-4-yl]isoquinolin-3-yl]-2-methyl-1,3-dihydroisoindole-5-carboxamide;N-[6-[5-(hydroxymethyl)-1-methylpyrazol-4-yl]isoquinolin-3-yl]-2-methyl-3,4-dihydro-1H-isoquinoline-6-carboxamide;N-[6-[5-(hydroxymethyl)-1-methylpyrazol-4-yl]isoquinolin-3-yl]-2-(1-methylpiperidin-4-yl)sulfanylpyridine-4-carboxamide;N-[6-[5-(hydroxymethyl)-1-methylpyrazol-4-yl]isoquinolin-3-yl]-2-(1-propan-2-ylpiperidin-4-yl)oxypyridine-4-carboxamide;N-[6-[5-(hydroxymethyl)-1-methylpyrazol-4-yl]isoquinolin-3-yl]-5,6,7,8-tetrahydronaphthalene-2-carboxamide;2-(7-methyl-2,7-diazaspiro[3.5]nonan-2-yl)-N-[6-[1-methyl-5-(piperidin-1-ylmethyl)pyrazol-4-yl]isoquinolin-3-yl]pyridine-4-carboxamide;4-methyl-N-[6-[1-methyl-5-(morpholin-4-ylmethyl)pyrazol-4-yl]isoquinolin-3-yl]benzamide;4-methyl-N-[6-[1-methyl-5-(piperidin-1-ylmethyl)pyrazol-4-yl]isoquinolin-3-yl]benzamide;4-methyl-N-[6-[1-methyl-5-(pyrrolidin-1-ylmethyl)pyrazol-4-yl]isoquinolin-3-yl]benzamide;N-[6-[1-methyl-5-(piperidin-1-ylmethyl)pyrazol-4-yl]isoquinolin-3-yl]-3-(pyrrolidin-1-ylmethyl)benzamide (PubChem CID 157399272) has the molecular formula C324H345FN64O22S and a molecular weight of 5538.82 g/mol. Its IUPAC name is 3-cyclobutyloxy-N-[6-[5-(hydroxymethyl)-1-methylpyrazol-4-yl]isoquinolin-3-yl]benzamide;4-(1-fluoroethoxy)-N-[6-[1-methyl-5-(piperidin-1-ylmethyl)pyrazol-4-yl]isoquinolin-3-yl]benzamide;N-[6-[5-(hydroxymethyl)-1-methylpyrazol-4-yl]isoquinolin-3-yl]-2-methyl-1,3-dihydroisoindole-5-carboxamide;N-[6-[5-(hydroxymethyl)-1-methylpyrazol-4-yl]isoquinolin-3-yl]-2-methyl-3,4-dihydro-1H-isoquinoline-6-carboxamide;N-[6-[5-(hydroxymethyl)-1-methylpyrazol-4-yl]isoquinolin-3-yl]-2-(1-methylpiperidin-4-yl)sulfanylpyridine-4-carboxamide;N-[6-[5-(hydroxymethyl)-1-methylpyrazol-4-yl]isoquinolin-3-yl]-2-(1-propan-2-ylpiperidin-4-yl)oxypyridine-4-carboxamide;N-[6-[5-(hydroxymethyl)-1-methylpyrazol-4-yl]isoquinolin-3-yl]-5,6,7,8-tetrahydronaphthalene-2-carboxamide;2-(7-methyl-2,7-diazaspiro[3.5]nonan-2-yl)-N-[6-[1-methyl-5-(piperidin-1-ylmethyl)pyrazol-4-yl]isoquinolin-3-yl]pyridine-4-carboxamide;4-methyl-N-[6-[1-methyl-5-(morpholin-4-ylmethyl)pyrazol-4-yl]isoquinolin-3-yl]benzamide;4-methyl-N-[6-[1-methyl-5-(piperidin-1-ylmethyl)pyrazol-4-yl]isoquinolin-3-yl]benzamide;4-methyl-N-[6-[1-methyl-5-(pyrrolidin-1-ylmethyl)pyrazol-4-yl]isoquinolin-3-yl]benzamide;N-[6-[1-methyl-5-(piperidin-1-ylmethyl)pyrazol-4-yl]isoquinolin-3-yl]-3-(pyrrolidin-1-ylmethyl)benzamide.

Molecular Properties

Compound Name3-cyclobutyloxy-N-[6-[5-(hydroxymethyl)-1-methylpyrazol-4-yl]isoquinolin-3-yl]benzamide;4-(1-fluoroethoxy)-N-[6-[1-methyl-5-(piperidin-1-ylmethyl)pyrazol-4-yl]isoquinolin-3-yl]benzamide;N-[6-[5-(hydroxymethyl)-1-methylpyrazol-4-yl]isoquinolin-3-yl]-2-methyl-1,3-dihydroisoindole-5-carboxamide;N-[6-[5-(hydroxymethyl)-1-methylpyrazol-4-yl]isoquinolin-3-yl]-2-methyl-3,4-dihydro-1H-isoquinoline-6-carboxamide;N-[6-[5-(hydroxymethyl)-1-methylpyrazol-4-yl]isoquinolin-3-yl]-2-(1-methylpiperidin-4-yl)sulfanylpyridine-4-carboxamide;N-[6-[5-(hydroxymethyl)-1-methylpyrazol-4-yl]isoquinolin-3-yl]-2-(1-propan-2-ylpiperidin-4-yl)oxypyridine-4-carboxamide;N-[6-[5-(hydroxymethyl)-1-methylpyrazol-4-yl]isoquinolin-3-yl]-5,6,7,8-tetrahydronaphthalene-2-carboxamide;2-(7-methyl-2,7-diazaspiro[3.5]nonan-2-yl)-N-[6-[1-methyl-5-(piperidin-1-ylmethyl)pyrazol-4-yl]isoquinolin-3-yl]pyridine-4-carboxamide;4-methyl-N-[6-[1-methyl-5-(morpholin-4-ylmethyl)pyrazol-4-yl]isoquinolin-3-yl]benzamide;4-methyl-N-[6-[1-methyl-5-(piperidin-1-ylmethyl)pyrazol-4-yl]isoquinolin-3-yl]benzamide;4-methyl-N-[6-[1-methyl-5-(pyrrolidin-1-ylmethyl)pyrazol-4-yl]isoquinolin-3-yl]benzamide;N-[6-[1-methyl-5-(piperidin-1-ylmethyl)pyrazol-4-yl]isoquinolin-3-yl]-3-(pyrrolidin-1-ylmethyl)benzamide
PubChem CID157399272
Molecular FormulaC324H345FN64O22S
Molecular Weight5538.82 g/mol
Exact Mass5534.75
IUPAC Name3-cyclobutyloxy-N-[6-[5-(hydroxymethyl)-1-methylpyrazol-4-yl]isoquinolin-3-yl]benzamide;4-(1-fluoroethoxy)-N-[6-[1-methyl-5-(piperidin-1-ylmethyl)pyrazol-4-yl]isoquinolin-3-yl]benzamide;N-[6-[5-(hydroxymethyl)-1-methylpyrazol-4-yl]isoquinolin-3-yl]-2-methyl-1,3-dihydroisoindole-5-carboxamide;N-[6-[5-(hydroxymethyl)-1-methylpyrazol-4-yl]isoquinolin-3-yl]-2-methyl-3,4-dihydro-1H-isoquinoline-6-carboxamide;N-[6-[5-(hydroxymethyl)-1-methylpyrazol-4-yl]isoquinolin-3-yl]-2-(1-methylpiperidin-4-yl)sulfanylpyridine-4-carboxamide;N-[6-[5-(hydroxymethyl)-1-methylpyrazol-4-yl]isoquinolin-3-yl]-2-(1-propan-2-ylpiperidin-4-yl)oxypyridine-4-carboxamide;N-[6-[5-(hydroxymethyl)-1-methylpyrazol-4-yl]isoquinolin-3-yl]-5,6,7,8-tetrahydronaphthalene-2-carboxamide;2-(7-methyl-2,7-diazaspiro[3.5]nonan-2-yl)-N-[6-[1-methyl-5-(piperidin-1-ylmethyl)pyrazol-4-yl]isoquinolin-3-yl]pyridine-4-carboxamide;4-methyl-N-[6-[1-methyl-5-(morpholin-4-ylmethyl)pyrazol-4-yl]isoquinolin-3-yl]benzamide;4-methyl-N-[6-[1-methyl-5-(piperidin-1-ylmethyl)pyrazol-4-yl]isoquinolin-3-yl]benzamide;4-methyl-N-[6-[1-methyl-5-(pyrrolidin-1-ylmethyl)pyrazol-4-yl]isoquinolin-3-yl]benzamide;N-[6-[1-methyl-5-(piperidin-1-ylmethyl)pyrazol-4-yl]isoquinolin-3-yl]-3-(pyrrolidin-1-ylmethyl)benzamide
SMILESCC(C)N1CCC(Oc2cc(C(=O)Nc3cc4cc(-c5cnn(C)c5CO)ccc4cn3)ccn2)CC1.CC(F)Oc1ccc(C(=O)Nc2cc3cc(-c4cnn(C)c4CN4CCCCC4)ccc3cn2)cc1.CN1CCC(Sc2cc(C(=O)Nc3cc4cc(-c5cnn(C)c5CO)ccc4cn3)ccn2)CC1.CN1CCC2(CC1)CN(c1cc(C(=O)Nc3cc4cc(-c5cnn(C)c5CN5CCCCC5)ccc4cn3)ccn1)C2.CN1CCc2cc(C(=O)Nc3cc4cc(-c5cnn(C)c5CO)ccc4cn3)ccc2C1.CN1Cc2ccc(C(=O)Nc3cc4cc(-c5cnn(C)c5CO)ccc4cn3)cc2C1.Cc1ccc(C(=O)Nc2cc3cc(-c4cnn(C)c4CN4CCCC4)ccc3cn2)cc1.Cc1ccc(C(=O)Nc2cc3cc(-c4cnn(C)c4CN4CCCCC4)ccc3cn2)cc1.Cc1ccc(C(=O)Nc2cc3cc(-c4cnn(C)c4CN4CCOCC4)ccc3cn2)cc1.Cn1ncc(-c2ccc3cnc(NC(=O)c4ccc5c(c4)CCCC5)cc3c2)c1CO.Cn1ncc(-c2ccc3cnc(NC(=O)c4cccc(CN5CCCC5)c4)cc3c2)c1CN1CCCCC1.Cn1ncc(-c2ccc3cnc(NC(=O)c4cccc(OC5CCC5)c4)cc3c2)c1CO
InChIInChI=1S/C33H40N8O.C31H36N6O.C28H30FN5O2.C28H32N6O3.C27H29N5O.C26H28N6O2S.C26H27N5O2.C26H27N5O.C25H25N5O2.C25H24N4O3.C25H24N4O2.C24H23N5O2/c1-38-14-9-33(10-15-38)22-41(23-33)31-18-25(8-11-34-31)32(42)37-30-17-27-16-24(6-7-26(27)19-35-30)28-20-36-39(2)29(28)21-40-12-4-3-5-13-40;1-35-29(22-37-12-3-2-4-13-37)28(20-33-35)24-10-11-26-19-32-30(18-27(26)17-24)34-31(38)25-9-7-8-23(16-25)21-36-14-5-6-15-36;1-19(29)36-24-10-8-20(9-11-24)28(35)32-27-15-23-14-21(6-7-22(23)16-30-27)25-17-31-33(2)26(25)18-34-12-4-3-5-13-34;1-18(2)34-10-7-23(8-11-34)37-27-14-20(6-9-29-27)28(36)32-26-13-22-12-19(4-5-21(22)15-30-26)24-16-31-33(3)25(24)17-35;1-19-6-8-20(9-7-19)27(33)30-26-15-23-14-21(10-11-22(23)16-28-26)24-17-29-31(2)25(24)18-32-12-4-3-5-13-32;1-31-9-6-21(7-10-31)35-25-13-18(5-8-27-25)26(34)30-24-12-20-11-17(3-4-19(20)14-28-24)22-15-29-32(2)23(22)16-33;1-18-3-5-19(6-4-18)26(32)29-25-14-22-13-20(7-8-21(22)15-27-25)23-16-28-30(2)24(23)17-31-9-11-33-12-10-31;1-18-5-7-19(8-6-18)26(32)29-25-14-22-13-20(9-10-21(22)15-27-25)23-16-28-30(2)24(23)17-31-11-3-4-12-31;1-29-8-7-16-9-18(4-6-20(16)14-29)25(32)28-24-11-21-10-17(3-5-19(21)12-26-24)22-13-27-30(2)23(22)15-31;1-29-23(15-30)22(14-27-29)16-8-9-18-13-26-24(12-19(18)10-16)28-25(31)17-4-2-7-21(11-17)32-20-5-3-6-20;1-29-23(15-30)22(14-27-29)18-7-9-20-13-26-24(12-21(20)11-18)28-25(31)19-8-6-16-4-2-3-5-17(16)10-19;1-28-12-18-6-4-16(8-20(18)13-28)24(31)27-23-9-19-7-15(3-5-17(19)10-25-23)21-11-26-29(2)22(21)14-30/h6-8,11,16-20H,3-5,9-10,12-15,21-23H2,1-2H3,(H,35,37,42);7-11,16-20H,2-6,12-15,21-22H2,1H3,(H,32,34,38);6-11,14-17,19H,3-5,12-13,18H2,1-2H3,(H,30,32,35);4-6,9,12-16,18,23,35H,7-8,10-11,17H2,1-3H3,(H,30,32,36);6-11,14-17H,3-5,12-13,18H2,1-2H3,(H,28,30,33);3-5,8,11-15,21,33H,6-7,9-10,16H2,1-2H3,(H,28,30,34);3-8,13-16H,9-12,17H2,1-2H3,(H,27,29,32);5-10,13-16H,3-4,11-12,17H2,1-2H3,(H,27,29,32);3-6,9-13,31H,7-8,14-15H2,1-2H3,(H,26,28,32);2,4,7-14,20,30H,3,5-6,15H2,1H3,(H,26,28,31);6-14,30H,2-5,15H2,1H3,(H,26,28,31);3-11,30H,12-14H2,1-2H3,(H,25,27,31)
InChIKeyBMYHUXRHFTYHQV-UHFFFAOYSA-N
XLogP53.09
TPSA956.81 Ų
H-Bond Donors18
H-Bond Acceptors75
Rotatable Bonds66
Heavy Atoms412
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5005538.82
LogP ≤ 553.09
H-Bond Donors ≤ 518
H-Bond Acceptors ≤ 1075

Analyze 3-cyclobutyloxy-N-[6-[5-(hydroxymethyl)-1-methylpyrazol-4-yl]isoquinolin-3-yl]benzamide;4-(1-fluoroethoxy)-N-[6-[1-methyl-5-(piperidin-1-ylmethyl)pyrazol-4-yl]isoquinolin-3-yl]benzamide;N-[6-[5-(hydroxymethyl)-1-methylpyrazol-4-yl]isoquinolin-3-yl]-2-methyl-1,3-dihydroisoindole-5-carboxamide;N-[6-[5-(hydroxymethyl)-1-methylpyrazol-4-yl]isoquinolin-3-yl]-2-methyl-3,4-dihydro-1H-isoquinoline-6-carboxamide;N-[6-[5-(hydroxymethyl)-1-methylpyrazol-4-yl]isoquinolin-3-yl]-2-(1-methylpiperidin-4-yl)sulfanylpyridine-4-carboxamide;N-[6-[5-(hydroxymethyl)-1-methylpyrazol-4-yl]isoquinolin-3-yl]-2-(1-propan-2-ylpiperidin-4-yl)oxypyridine-4-carboxamide;N-[6-[5-(hydroxymethyl)-1-methylpyrazol-4-yl]isoquinolin-3-yl]-5,6,7,8-tetrahydronaphthalene-2-carboxamide;2-(7-methyl-2,7-diazaspiro[3.5]nonan-2-yl)-N-[6-[1-methyl-5-(piperidin-1-ylmethyl)pyrazol-4-yl]isoquinolin-3-yl]pyridine-4-carboxamide;4-methyl-N-[6-[1-methyl-5-(morpholin-4-ylmethyl)pyrazol-4-yl]isoquinolin-3-yl]benzamide;4-methyl-N-[6-[1-methyl-5-(piperidin-1-ylmethyl)pyrazol-4-yl]isoquinolin-3-yl]benzamide;4-methyl-N-[6-[1-methyl-5-(pyrrolidin-1-ylmethyl)pyrazol-4-yl]isoquinolin-3-yl]benzamide;N-[6-[1-methyl-5-(piperidin-1-ylmethyl)pyrazol-4-yl]isoquinolin-3-yl]-3-(pyrrolidin-1-ylmethyl)benzamide with MolForge

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Frequently Asked Questions

What is the IUPAC name of 3-cyclobutyloxy-N-[6-[5-(hydroxymethyl)-1-methylpyrazol-4-yl]isoquinolin-3-yl]benzamide;4-(1-fluoroethoxy)-N-[6-[1-methyl-5-(piperidin-1-ylmethyl)pyrazol-4-yl]isoquinolin-3-yl]benzamide;N-[6-[5-(hydroxymethyl)-1-methylpyrazol-4-yl]isoquinolin-3-yl]-2-methyl-1,3-dihydroisoindole-5-carboxamide;N-[6-[5-(hydroxymethyl)-1-methylpyrazol-4-yl]isoquinolin-3-yl]-2-methyl-3,4-dihydro-1H-isoquinoline-6-carboxamide;N-[6-[5-(hydroxymethyl)-1-methylpyrazol-4-yl]isoquinolin-3-yl]-2-(1-methylpiperidin-4-yl)sulfanylpyridine-4-carboxamide;N-[6-[5-(hydroxymethyl)-1-methylpyrazol-4-yl]isoquinolin-3-yl]-2-(1-propan-2-ylpiperidin-4-yl)oxypyridine-4-carboxamide;N-[6-[5-(hydroxymethyl)-1-methylpyrazol-4-yl]isoquinolin-3-yl]-5,6,7,8-tetrahydronaphthalene-2-carboxamide;2-(7-methyl-2,7-diazaspiro[3.5]nonan-2-yl)-N-[6-[1-methyl-5-(piperidin-1-ylmethyl)pyrazol-4-yl]isoquinolin-3-yl]pyridine-4-carboxamide;4-methyl-N-[6-[1-methyl-5-(morpholin-4-ylmethyl)pyrazol-4-yl]isoquinolin-3-yl]benzamide;4-methyl-N-[6-[1-methyl-5-(piperidin-1-ylmethyl)pyrazol-4-yl]isoquinolin-3-yl]benzamide;4-methyl-N-[6-[1-methyl-5-(pyrrolidin-1-ylmethyl)pyrazol-4-yl]isoquinolin-3-yl]benzamide;N-[6-[1-methyl-5-(piperidin-1-ylmethyl)pyrazol-4-yl]isoquinolin-3-yl]-3-(pyrrolidin-1-ylmethyl)benzamide?
The IUPAC name of 3-cyclobutyloxy-N-[6-[5-(hydroxymethyl)-1-methylpyrazol-4-yl]isoquinolin-3-yl]benzamide;4-(1-fluoroethoxy)-N-[6-[1-methyl-5-(piperidin-1-ylmethyl)pyrazol-4-yl]isoquinolin-3-yl]benzamide;N-[6-[5-(hydroxymethyl)-1-methylpyrazol-4-yl]isoquinolin-3-yl]-2-methyl-1,3-dihydroisoindole-5-carboxamide;N-[6-[5-(hydroxymethyl)-1-methylpyrazol-4-yl]isoquinolin-3-yl]-2-methyl-3,4-dihydro-1H-isoquinoline-6-carboxamide;N-[6-[5-(hydroxymethyl)-1-methylpyrazol-4-yl]isoquinolin-3-yl]-2-(1-methylpiperidin-4-yl)sulfanylpyridine-4-carboxamide;N-[6-[5-(hydroxymethyl)-1-methylpyrazol-4-yl]isoquinolin-3-yl]-2-(1-propan-2-ylpiperidin-4-yl)oxypyridine-4-carboxamide;N-[6-[5-(hydroxymethyl)-1-methylpyrazol-4-yl]isoquinolin-3-yl]-5,6,7,8-tetrahydronaphthalene-2-carboxamide;2-(7-methyl-2,7-diazaspiro[3.5]nonan-2-yl)-N-[6-[1-methyl-5-(piperidin-1-ylmethyl)pyrazol-4-yl]isoquinolin-3-yl]pyridine-4-carboxamide;4-methyl-N-[6-[1-methyl-5-(morpholin-4-ylmethyl)pyrazol-4-yl]isoquinolin-3-yl]benzamide;4-methyl-N-[6-[1-methyl-5-(piperidin-1-ylmethyl)pyrazol-4-yl]isoquinolin-3-yl]benzamide;4-methyl-N-[6-[1-methyl-5-(pyrrolidin-1-ylmethyl)pyrazol-4-yl]isoquinolin-3-yl]benzamide;N-[6-[1-methyl-5-(piperidin-1-ylmethyl)pyrazol-4-yl]isoquinolin-3-yl]-3-(pyrrolidin-1-ylmethyl)benzamide (CID 157399272) is 3-cyclobutyloxy-N-[6-[5-(hydroxymethyl)-1-methylpyrazol-4-yl]isoquinolin-3-yl]benzamide;4-(1-fluoroethoxy)-N-[6-[1-methyl-5-(piperidin-1-ylmethyl)pyrazol-4-yl]isoquinolin-3-yl]benzamide;N-[6-[5-(hydroxymethyl)-1-methylpyrazol-4-yl]isoquinolin-3-yl]-2-methyl-1,3-dihydroisoindole-5-carboxamide;N-[6-[5-(hydroxymethyl)-1-methylpyrazol-4-yl]isoquinolin-3-yl]-2-methyl-3,4-dihydro-1H-isoquinoline-6-carboxamide;N-[6-[5-(hydroxymethyl)-1-methylpyrazol-4-yl]isoquinolin-3-yl]-2-(1-methylpiperidin-4-yl)sulfanylpyridine-4-carboxamide;N-[6-[5-(hydroxymethyl)-1-methylpyrazol-4-yl]isoquinolin-3-yl]-2-(1-propan-2-ylpiperidin-4-yl)oxypyridine-4-carboxamide;N-[6-[5-(hydroxymethyl)-1-methylpyrazol-4-yl]isoquinolin-3-yl]-5,6,7,8-tetrahydronaphthalene-2-carboxamide;2-(7-methyl-2,7-diazaspiro[3.5]nonan-2-yl)-N-[6-[1-methyl-5-(piperidin-1-ylmethyl)pyrazol-4-yl]isoquinolin-3-yl]pyridine-4-carboxamide;4-methyl-N-[6-[1-methyl-5-(morpholin-4-ylmethyl)pyrazol-4-yl]isoquinolin-3-yl]benzamide;4-methyl-N-[6-[1-methyl-5-(piperidin-1-ylmethyl)pyrazol-4-yl]isoquinolin-3-yl]benzamide;4-methyl-N-[6-[1-methyl-5-(pyrrolidin-1-ylmethyl)pyrazol-4-yl]isoquinolin-3-yl]benzamide;N-[6-[1-methyl-5-(piperidin-1-ylmethyl)pyrazol-4-yl]isoquinolin-3-yl]-3-(pyrrolidin-1-ylmethyl)benzamide.
What is the SMILES notation for 3-cyclobutyloxy-N-[6-[5-(hydroxymethyl)-1-methylpyrazol-4-yl]isoquinolin-3-yl]benzamide;4-(1-fluoroethoxy)-N-[6-[1-methyl-5-(piperidin-1-ylmethyl)pyrazol-4-yl]isoquinolin-3-yl]benzamide;N-[6-[5-(hydroxymethyl)-1-methylpyrazol-4-yl]isoquinolin-3-yl]-2-methyl-1,3-dihydroisoindole-5-carboxamide;N-[6-[5-(hydroxymethyl)-1-methylpyrazol-4-yl]isoquinolin-3-yl]-2-methyl-3,4-dihydro-1H-isoquinoline-6-carboxamide;N-[6-[5-(hydroxymethyl)-1-methylpyrazol-4-yl]isoquinolin-3-yl]-2-(1-methylpiperidin-4-yl)sulfanylpyridine-4-carboxamide;N-[6-[5-(hydroxymethyl)-1-methylpyrazol-4-yl]isoquinolin-3-yl]-2-(1-propan-2-ylpiperidin-4-yl)oxypyridine-4-carboxamide;N-[6-[5-(hydroxymethyl)-1-methylpyrazol-4-yl]isoquinolin-3-yl]-5,6,7,8-tetrahydronaphthalene-2-carboxamide;2-(7-methyl-2,7-diazaspiro[3.5]nonan-2-yl)-N-[6-[1-methyl-5-(piperidin-1-ylmethyl)pyrazol-4-yl]isoquinolin-3-yl]pyridine-4-carboxamide;4-methyl-N-[6-[1-methyl-5-(morpholin-4-ylmethyl)pyrazol-4-yl]isoquinolin-3-yl]benzamide;4-methyl-N-[6-[1-methyl-5-(piperidin-1-ylmethyl)pyrazol-4-yl]isoquinolin-3-yl]benzamide;4-methyl-N-[6-[1-methyl-5-(pyrrolidin-1-ylmethyl)pyrazol-4-yl]isoquinolin-3-yl]benzamide;N-[6-[1-methyl-5-(piperidin-1-ylmethyl)pyrazol-4-yl]isoquinolin-3-yl]-3-(pyrrolidin-1-ylmethyl)benzamide?
The canonical SMILES for 3-cyclobutyloxy-N-[6-[5-(hydroxymethyl)-1-methylpyrazol-4-yl]isoquinolin-3-yl]benzamide;4-(1-fluoroethoxy)-N-[6-[1-methyl-5-(piperidin-1-ylmethyl)pyrazol-4-yl]isoquinolin-3-yl]benzamide;N-[6-[5-(hydroxymethyl)-1-methylpyrazol-4-yl]isoquinolin-3-yl]-2-methyl-1,3-dihydroisoindole-5-carboxamide;N-[6-[5-(hydroxymethyl)-1-methylpyrazol-4-yl]isoquinolin-3-yl]-2-methyl-3,4-dihydro-1H-isoquinoline-6-carboxamide;N-[6-[5-(hydroxymethyl)-1-methylpyrazol-4-yl]isoquinolin-3-yl]-2-(1-methylpiperidin-4-yl)sulfanylpyridine-4-carboxamide;N-[6-[5-(hydroxymethyl)-1-methylpyrazol-4-yl]isoquinolin-3-yl]-2-(1-propan-2-ylpiperidin-4-yl)oxypyridine-4-carboxamide;N-[6-[5-(hydroxymethyl)-1-methylpyrazol-4-yl]isoquinolin-3-yl]-5,6,7,8-tetrahydronaphthalene-2-carboxamide;2-(7-methyl-2,7-diazaspiro[3.5]nonan-2-yl)-N-[6-[1-methyl-5-(piperidin-1-ylmethyl)pyrazol-4-yl]isoquinolin-3-yl]pyridine-4-carboxamide;4-methyl-N-[6-[1-methyl-5-(morpholin-4-ylmethyl)pyrazol-4-yl]isoquinolin-3-yl]benzamide;4-methyl-N-[6-[1-methyl-5-(piperidin-1-ylmethyl)pyrazol-4-yl]isoquinolin-3-yl]benzamide;4-methyl-N-[6-[1-methyl-5-(pyrrolidin-1-ylmethyl)pyrazol-4-yl]isoquinolin-3-yl]benzamide;N-[6-[1-methyl-5-(piperidin-1-ylmethyl)pyrazol-4-yl]isoquinolin-3-yl]-3-(pyrrolidin-1-ylmethyl)benzamide is CC(C)N1CCC(Oc2cc(C(=O)Nc3cc4cc(-c5cnn(C)c5CO)ccc4cn3)ccn2)CC1.CC(F)Oc1ccc(C(=O)Nc2cc3cc(-c4cnn(C)c4CN4CCCCC4)ccc3cn2)cc1.CN1CCC(Sc2cc(C(=O)Nc3cc4cc(-c5cnn(C)c5CO)ccc4cn3)ccn2)CC1.CN1CCC2(CC1)CN(c1cc(C(=O)Nc3cc4cc(-c5cnn(C)c5CN5CCCCC5)ccc4cn3)ccn1)C2.CN1CCc2cc(C(=O)Nc3cc4cc(-c5cnn(C)c5CO)ccc4cn3)ccc2C1.CN1Cc2ccc(C(=O)Nc3cc4cc(-c5cnn(C)c5CO)ccc4cn3)cc2C1.Cc1ccc(C(=O)Nc2cc3cc(-c4cnn(C)c4CN4CCCC4)ccc3cn2)cc1.Cc1ccc(C(=O)Nc2cc3cc(-c4cnn(C)c4CN4CCCCC4)ccc3cn2)cc1.Cc1ccc(C(=O)Nc2cc3cc(-c4cnn(C)c4CN4CCOCC4)ccc3cn2)cc1.Cn1ncc(-c2ccc3cnc(NC(=O)c4ccc5c(c4)CCCC5)cc3c2)c1CO.Cn1ncc(-c2ccc3cnc(NC(=O)c4cccc(CN5CCCC5)c4)cc3c2)c1CN1CCCCC1.Cn1ncc(-c2ccc3cnc(NC(=O)c4cccc(OC5CCC5)c4)cc3c2)c1CO.
What is the InChIKey of 3-cyclobutyloxy-N-[6-[5-(hydroxymethyl)-1-methylpyrazol-4-yl]isoquinolin-3-yl]benzamide;4-(1-fluoroethoxy)-N-[6-[1-methyl-5-(piperidin-1-ylmethyl)pyrazol-4-yl]isoquinolin-3-yl]benzamide;N-[6-[5-(hydroxymethyl)-1-methylpyrazol-4-yl]isoquinolin-3-yl]-2-methyl-1,3-dihydroisoindole-5-carboxamide;N-[6-[5-(hydroxymethyl)-1-methylpyrazol-4-yl]isoquinolin-3-yl]-2-methyl-3,4-dihydro-1H-isoquinoline-6-carboxamide;N-[6-[5-(hydroxymethyl)-1-methylpyrazol-4-yl]isoquinolin-3-yl]-2-(1-methylpiperidin-4-yl)sulfanylpyridine-4-carboxamide;N-[6-[5-(hydroxymethyl)-1-methylpyrazol-4-yl]isoquinolin-3-yl]-2-(1-propan-2-ylpiperidin-4-yl)oxypyridine-4-carboxamide;N-[6-[5-(hydroxymethyl)-1-methylpyrazol-4-yl]isoquinolin-3-yl]-5,6,7,8-tetrahydronaphthalene-2-carboxamide;2-(7-methyl-2,7-diazaspiro[3.5]nonan-2-yl)-N-[6-[1-methyl-5-(piperidin-1-ylmethyl)pyrazol-4-yl]isoquinolin-3-yl]pyridine-4-carboxamide;4-methyl-N-[6-[1-methyl-5-(morpholin-4-ylmethyl)pyrazol-4-yl]isoquinolin-3-yl]benzamide;4-methyl-N-[6-[1-methyl-5-(piperidin-1-ylmethyl)pyrazol-4-yl]isoquinolin-3-yl]benzamide;4-methyl-N-[6-[1-methyl-5-(pyrrolidin-1-ylmethyl)pyrazol-4-yl]isoquinolin-3-yl]benzamide;N-[6-[1-methyl-5-(piperidin-1-ylmethyl)pyrazol-4-yl]isoquinolin-3-yl]-3-(pyrrolidin-1-ylmethyl)benzamide?
The InChIKey is BMYHUXRHFTYHQV-UHFFFAOYSA-N. The full InChI is InChI=1S/C33H40N8O.C31H36N6O.C28H30FN5O2.C28H32N6O3.C27H29N5O.C26H28N6O2S.C26H27N5O2.C26H27N5O.C25H25N5O2.C25H24N4O3.C25H24N4O2.C24H23N5O2/c1-38-14-9-33(10-15-38)22-41(23-33)31-18-25(8-11-34-31)32(42)37-30-17-27-16-24(6-7-26(27)19-35-30)28-20-36-39(2)29(28)21-40-12-4-3-5-13-40;1-35-29(22-37-12-3-2-4-13-37)28(20-33-35)24-10-11-26-19-32-30(18-27(26)17-24)34-31(38)25-9-7-8-23(16-25)21-36-14-5-6-15-36;1-19(29)36-24-10-8-20(9-11-24)28(35)32-27-15-23-14-21(6-7-22(23)16-30-27)25-17-31-33(2)26(25)18-34-12-4-3-5-13-34;1-18(2)34-10-7-23(8-11-34)37-27-14-20(6-9-29-27)28(36)32-26-13-22-12-19(4-5-21(22)15-30-26)24-16-31-33(3)25(24)17-35;1-19-6-8-20(9-7-19)27(33)30-26-15-23-14-21(10-11-22(23)16-28-26)24-17-29-31(2)25(24)18-32-12-4-3-5-13-32;1-31-9-6-21(7-10-31)35-25-13-18(5-8-27-25)26(34)30-24-12-20-11-17(3-4-19(20)14-28-24)22-15-29-32(2)23(22)16-33;1-18-3-5-19(6-4-18)26(32)29-25-14-22-13-20(7-8-21(22)15-27-25)23-16-28-30(2)24(23)17-31-9-11-33-12-10-31;1-18-5-7-19(8-6-18)26(32)29-25-14-22-13-20(9-10-21(22)15-27-25)23-16-28-30(2)24(23)17-31-11-3-4-12-31;1-29-8-7-16-9-18(4-6-20(16)14-29)25(32)28-24-11-21-10-17(3-5-19(21)12-26-24)22-13-27-30(2)23(22)15-31;1-29-23(15-30)22(14-27-29)16-8-9-18-13-26-24(12-19(18)10-16)28-25(31)17-4-2-7-21(11-17)32-20-5-3-6-20;1-29-23(15-30)22(14-27-29)18-7-9-20-13-26-24(12-21(20)11-18)28-25(31)19-8-6-16-4-2-3-5-17(16)10-19;1-28-12-18-6-4-16(8-20(18)13-28)24(31)27-23-9-19-7-15(3-5-17(19)10-25-23)21-11-26-29(2)22(21)14-30/h6-8,11,16-20H,3-5,9-10,12-15,21-23H2,1-2H3,(H,35,37,42);7-11,16-20H,2-6,12-15,21-22H2,1H3,(H,32,34,38);6-11,14-17,19H,3-5,12-13,18H2,1-2H3,(H,30,32,35);4-6,9,12-16,18,23,35H,7-8,10-11,17H2,1-3H3,(H,30,32,36);6-11,14-17H,3-5,12-13,18H2,1-2H3,(H,28,30,33);3-5,8,11-15,21,33H,6-7,9-10,16H2,1-2H3,(H,28,30,34);3-8,13-16H,9-12,17H2,1-2H3,(H,27,29,32);5-10,13-16H,3-4,11-12,17H2,1-2H3,(H,27,29,32);3-6,9-13,31H,7-8,14-15H2,1-2H3,(H,26,28,32);2,4,7-14,20,30H,3,5-6,15H2,1H3,(H,26,28,31);6-14,30H,2-5,15H2,1H3,(H,26,28,31);3-11,30H,12-14H2,1-2H3,(H,25,27,31).
What are the key properties of 3-cyclobutyloxy-N-[6-[5-(hydroxymethyl)-1-methylpyrazol-4-yl]isoquinolin-3-yl]benzamide;4-(1-fluoroethoxy)-N-[6-[1-methyl-5-(piperidin-1-ylmethyl)pyrazol-4-yl]isoquinolin-3-yl]benzamide;N-[6-[5-(hydroxymethyl)-1-methylpyrazol-4-yl]isoquinolin-3-yl]-2-methyl-1,3-dihydroisoindole-5-carboxamide;N-[6-[5-(hydroxymethyl)-1-methylpyrazol-4-yl]isoquinolin-3-yl]-2-methyl-3,4-dihydro-1H-isoquinoline-6-carboxamide;N-[6-[5-(hydroxymethyl)-1-methylpyrazol-4-yl]isoquinolin-3-yl]-2-(1-methylpiperidin-4-yl)sulfanylpyridine-4-carboxamide;N-[6-[5-(hydroxymethyl)-1-methylpyrazol-4-yl]isoquinolin-3-yl]-2-(1-propan-2-ylpiperidin-4-yl)oxypyridine-4-carboxamide;N-[6-[5-(hydroxymethyl)-1-methylpyrazol-4-yl]isoquinolin-3-yl]-5,6,7,8-tetrahydronaphthalene-2-carboxamide;2-(7-methyl-2,7-diazaspiro[3.5]nonan-2-yl)-N-[6-[1-methyl-5-(piperidin-1-ylmethyl)pyrazol-4-yl]isoquinolin-3-yl]pyridine-4-carboxamide;4-methyl-N-[6-[1-methyl-5-(morpholin-4-ylmethyl)pyrazol-4-yl]isoquinolin-3-yl]benzamide;4-methyl-N-[6-[1-methyl-5-(piperidin-1-ylmethyl)pyrazol-4-yl]isoquinolin-3-yl]benzamide;4-methyl-N-[6-[1-methyl-5-(pyrrolidin-1-ylmethyl)pyrazol-4-yl]isoquinolin-3-yl]benzamide;N-[6-[1-methyl-5-(piperidin-1-ylmethyl)pyrazol-4-yl]isoquinolin-3-yl]-3-(pyrrolidin-1-ylmethyl)benzamide?
3-cyclobutyloxy-N-[6-[5-(hydroxymethyl)-1-methylpyrazol-4-yl]isoquinolin-3-yl]benzamide;4-(1-fluoroethoxy)-N-[6-[1-methyl-5-(piperidin-1-ylmethyl)pyrazol-4-yl]isoquinolin-3-yl]benzamide;N-[6-[5-(hydroxymethyl)-1-methylpyrazol-4-yl]isoquinolin-3-yl]-2-methyl-1,3-dihydroisoindole-5-carboxamide;N-[6-[5-(hydroxymethyl)-1-methylpyrazol-4-yl]isoquinolin-3-yl]-2-methyl-3,4-dihydro-1H-isoquinoline-6-carboxamide;N-[6-[5-(hydroxymethyl)-1-methylpyrazol-4-yl]isoquinolin-3-yl]-2-(1-methylpiperidin-4-yl)sulfanylpyridine-4-carboxamide;N-[6-[5-(hydroxymethyl)-1-methylpyrazol-4-yl]isoquinolin-3-yl]-2-(1-propan-2-ylpiperidin-4-yl)oxypyridine-4-carboxamide;N-[6-[5-(hydroxymethyl)-1-methylpyrazol-4-yl]isoquinolin-3-yl]-5,6,7,8-tetrahydronaphthalene-2-carboxamide;2-(7-methyl-2,7-diazaspiro[3.5]nonan-2-yl)-N-[6-[1-methyl-5-(piperidin-1-ylmethyl)pyrazol-4-yl]isoquinolin-3-yl]pyridine-4-carboxamide;4-methyl-N-[6-[1-methyl-5-(morpholin-4-ylmethyl)pyrazol-4-yl]isoquinolin-3-yl]benzamide;4-methyl-N-[6-[1-methyl-5-(piperidin-1-ylmethyl)pyrazol-4-yl]isoquinolin-3-yl]benzamide;4-methyl-N-[6-[1-methyl-5-(pyrrolidin-1-ylmethyl)pyrazol-4-yl]isoquinolin-3-yl]benzamide;N-[6-[1-methyl-5-(piperidin-1-ylmethyl)pyrazol-4-yl]isoquinolin-3-yl]-3-(pyrrolidin-1-ylmethyl)benzamide has a molecular weight of 5538.82 g/mol, XLogP of 53.09, 66 rotatable bonds, 18 hydrogen bond donors, and 75 hydrogen bond acceptors.
Where does this data come from?
All data for 3-cyclobutyloxy-N-[6-[5-(hydroxymethyl)-1-methylpyrazol-4-yl]isoquinolin-3-yl]benzamide;4-(1-fluoroethoxy)-N-[6-[1-methyl-5-(piperidin-1-ylmethyl)pyrazol-4-yl]isoquinolin-3-yl]benzamide;N-[6-[5-(hydroxymethyl)-1-methylpyrazol-4-yl]isoquinolin-3-yl]-2-methyl-1,3-dihydroisoindole-5-carboxamide;N-[6-[5-(hydroxymethyl)-1-methylpyrazol-4-yl]isoquinolin-3-yl]-2-methyl-3,4-dihydro-1H-isoquinoline-6-carboxamide;N-[6-[5-(hydroxymethyl)-1-methylpyrazol-4-yl]isoquinolin-3-yl]-2-(1-methylpiperidin-4-yl)sulfanylpyridine-4-carboxamide;N-[6-[5-(hydroxymethyl)-1-methylpyrazol-4-yl]isoquinolin-3-yl]-2-(1-propan-2-ylpiperidin-4-yl)oxypyridine-4-carboxamide;N-[6-[5-(hydroxymethyl)-1-methylpyrazol-4-yl]isoquinolin-3-yl]-5,6,7,8-tetrahydronaphthalene-2-carboxamide;2-(7-methyl-2,7-diazaspiro[3.5]nonan-2-yl)-N-[6-[1-methyl-5-(piperidin-1-ylmethyl)pyrazol-4-yl]isoquinolin-3-yl]pyridine-4-carboxamide;4-methyl-N-[6-[1-methyl-5-(morpholin-4-ylmethyl)pyrazol-4-yl]isoquinolin-3-yl]benzamide;4-methyl-N-[6-[1-methyl-5-(piperidin-1-ylmethyl)pyrazol-4-yl]isoquinolin-3-yl]benzamide;4-methyl-N-[6-[1-methyl-5-(pyrrolidin-1-ylmethyl)pyrazol-4-yl]isoquinolin-3-yl]benzamide;N-[6-[1-methyl-5-(piperidin-1-ylmethyl)pyrazol-4-yl]isoquinolin-3-yl]-3-(pyrrolidin-1-ylmethyl)benzamide is sourced from PubChem (CID 157399272), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).