6-(8-chloro-4-fluoroquinolin-6-yl)-7-(1-methylpyrazol-3-yl)-1H-1,8-naphthyridin-4-one;6-(8-chloro-2-methylquinolin-6-yl)-7-(1-methylpyrazol-3-yl)-1H-1,8-naphthyridin-4-one;6-(8-chloro-2-methylquinolin-6-yl)-7-(3-methylpyrazol-1-yl)-1H-1,8-naphthyridin-4-one;6-(8-chloro-3-methylquinolin-6-yl)-7-(1-methylpyrazol-3-yl)-1H-1,8-naphthyridin-4-one;6-(8-chloro-5-methylquinolin-6-yl)-7-(1-methylpyrazol-3-yl)-1H-1,8-naphthyridin-4-one;6-(8-chloro-5-methylquinolin-6-yl)-7-phenyl-1H-1,8-naphthyridin-2-one

C133H93Cl6FN28O6 — CID 157399566

About 6-(8-chloro-4-fluoroquinolin-6-yl)-7-(1-methylpyrazol-3-yl)-1H-1,8-naphthyridin-4-one;6-(8-chloro-2-methylquinolin-6-yl)-7-(1-methylpyrazol-3-yl)-1H-1,8-naphthyridin-4-one;6-(8-chloro-2-methylquinolin-6-yl)-7-(3-methylpyrazol-1-yl)-1H-1,8-naphthyridin-4-one;6-(8-chloro-3-methylquinolin-6-yl)-7-(1-methylpyrazol-3-yl)-1H-1,8-naphthyridin-4-one;6-(8-chloro-5-methylquinolin-6-yl)-7-(1-methylpyrazol-3-yl)-1H-1,8-naphthyridin-4-one;6-(8-chloro-5-methylquinolin-6-yl)-7-phenyl-1H-1,8-naphthyridin-2-one

6-(8-chloro-4-fluoroquinolin-6-yl)-7-(1-methylpyrazol-3-yl)-1H-1,8-naphthyridin-4-one;6-(8-chloro-2-methylquinolin-6-yl)-7-(1-methylpyrazol-3-yl)-1H-1,8-naphthyridin-4-one;6-(8-chloro-2-methylquinolin-6-yl)-7-(3-methylpyrazol-1-yl)-1H-1,8-naphthyridin-4-one;6-(8-chloro-3-methylquinolin-6-yl)-7-(1-methylpyrazol-3-yl)-1H-1,8-naphthyridin-4-one;6-(8-chloro-5-methylquinolin-6-yl)-7-(1-methylpyrazol-3-yl)-1H-1,8-naphthyridin-4-one;6-(8-chloro-5-methylquinolin-6-yl)-7-phenyl-1H-1,8-naphthyridin-2-one (PubChem CID 157399566) has the molecular formula C133H93Cl6FN28O6 and a molecular weight of 2411.11 g/mol. Its IUPAC name is 6-(8-chloro-4-fluoroquinolin-6-yl)-7-(1-methylpyrazol-3-yl)-1H-1,8-naphthyridin-4-one;6-(8-chloro-2-methylquinolin-6-yl)-7-(1-methylpyrazol-3-yl)-1H-1,8-naphthyridin-4-one;6-(8-chloro-2-methylquinolin-6-yl)-7-(3-methylpyrazol-1-yl)-1H-1,8-naphthyridin-4-one;6-(8-chloro-3-methylquinolin-6-yl)-7-(1-methylpyrazol-3-yl)-1H-1,8-naphthyridin-4-one;6-(8-chloro-5-methylquinolin-6-yl)-7-(1-methylpyrazol-3-yl)-1H-1,8-naphthyridin-4-one;6-(8-chloro-5-methylquinolin-6-yl)-7-phenyl-1H-1,8-naphthyridin-2-one.

Molecular Properties

• Compound Name: 6-(8-chloro-4-fluoroquinolin-6-yl)-7-(1-methylpyrazol-3-yl)-1H-1,8-naphthyridin-4-one;6-(8-chloro-2-methylquinolin-6-yl)-7-(1-methylpyrazol-3-yl)-1H-1,8-naphthyridin-4-one;6-(8-chloro-2-methylquinolin-6-yl)-7-(3-methylpyrazol-1-yl)-1H-1,8-naphthyridin-4-one;6-(8-chloro-3-methylquinolin-6-yl)-7-(1-methylpyrazol-3-yl)-1H-1,8-naphthyridin-4-one;6-(8-chloro-5-methylquinolin-6-yl)-7-(1-methylpyrazol-3-yl)-1H-1,8-naphthyridin-4-one;6-(8-chloro-5-methylquinolin-6-yl)-7-phenyl-1H-1,8-naphthyridin-2-one
• PubChem CID: 157399566
• Molecular Formula: C133H93Cl6FN28O6
• Molecular Weight: 2411.11 g/mol
• Exact Mass: 2406.59
• IUPAC Name: 6-(8-chloro-4-fluoroquinolin-6-yl)-7-(1-methylpyrazol-3-yl)-1H-1,8-naphthyridin-4-one;6-(8-chloro-2-methylquinolin-6-yl)-7-(1-methylpyrazol-3-yl)-1H-1,8-naphthyridin-4-one;6-(8-chloro-2-methylquinolin-6-yl)-7-(3-methylpyrazol-1-yl)-1H-1,8-naphthyridin-4-one;6-(8-chloro-3-methylquinolin-6-yl)-7-(1-methylpyrazol-3-yl)-1H-1,8-naphthyridin-4-one;6-(8-chloro-5-methylquinolin-6-yl)-7-(1-methylpyrazol-3-yl)-1H-1,8-naphthyridin-4-one;6-(8-chloro-5-methylquinolin-6-yl)-7-phenyl-1H-1,8-naphthyridin-2-one
• SMILES: Cc1c(-c2cc3c(=O)cc[nH]c3nc2-c2ccn(C)n2)cc(Cl)c2ncccc12.Cc1c(-c2cc3ccc(=O)[nH]c3nc2-c2ccccc2)cc(Cl)c2ncccc12.Cc1ccc2cc(-c3cc4c(=O)cc[nH]c4nc3-c3ccn(C)n3)cc(Cl)c2n1.Cc1ccc2cc(-c3cc4c(=O)cc[nH]c4nc3-n3ccc(C)n3)cc(Cl)c2n1.Cc1cnc2c(Cl)cc(-c3cc4c(=O)cc[nH]c4nc3-c3ccn(C)n3)cc2c1.Cn1ccc(-c2nc3[nH]ccc(=O)c3cc2-c2cc(Cl)c3nccc(F)c3c2)n1
• InChI: InChI=1S/C24H16ClN3O.4C22H16ClN5O.C21H13ClFN5O/c1-14-17-8-5-11-26-23(17)20(25)13-18(14)19-12-16-9-10-21(29)27-24(16)28-22(19)15-6-3-2-4-7-15;1-12-7-14-8-13(9-17(23)20(14)25-11-12)15-10-16-19(29)3-5-24-22(16)26-21(15)18-4-6-28(2)27-18;1-12-3-4-13-9-14(10-17(23)20(13)25-12)15-11-16-19(29)5-7-24-22(16)26-21(15)18-6-8-28(2)27-18;1-12-3-4-14-9-15(10-18(23)20(14)25-12)16-11-17-19(29)5-7-24-21(17)26-22(16)28-8-6-13(2)27-28;1-12-13-4-3-7-24-20(13)17(23)11-14(12)15-10-16-19(29)5-8-25-22(16)26-21(15)18-6-9-28(2)27-18;1-28-7-4-17(27-28)20-12(10-14-18(29)3-6-25-21(14)26-20)11-8-13-16(23)2-5-24-19(13)15(22)9-11/h2-13H,1H3,(H,27,28,29);3*3-11H,1-2H3,(H,24,26,29);3-11H,1-2H3,(H,25,26,29);2-10H,1H3,(H,25,26,29)
• InChIKey: BMZDVMQJNDIIMK-UHFFFAOYSA-N
• XLogP: 28.19
• TPSA: 440.94 Ų
• H-Bond Donors: 6
• H-Bond Acceptors: 28
• Rotatable Bonds: 12
• Heavy Atoms: 174
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2411.11
LogP ≤ 5	28.19
H-Bond Donors ≤ 5	6
H-Bond Acceptors ≤ 10	28

Frequently Asked Questions

What is the IUPAC name of 6-(8-chloro-4-fluoroquinolin-6-yl)-7-(1-methylpyrazol-3-yl)-1H-1,8-naphthyridin-4-one;6-(8-chloro-2-methylquinolin-6-yl)-7-(1-methylpyrazol-3-yl)-1H-1,8-naphthyridin-4-one;6-(8-chloro-2-methylquinolin-6-yl)-7-(3-methylpyrazol-1-yl)-1H-1,8-naphthyridin-4-one;6-(8-chloro-3-methylquinolin-6-yl)-7-(1-methylpyrazol-3-yl)-1H-1,8-naphthyridin-4-one;6-(8-chloro-5-methylquinolin-6-yl)-7-(1-methylpyrazol-3-yl)-1H-1,8-naphthyridin-4-one;6-(8-chloro-5-methylquinolin-6-yl)-7-phenyl-1H-1,8-naphthyridin-2-one?

The IUPAC name of 6-(8-chloro-4-fluoroquinolin-6-yl)-7-(1-methylpyrazol-3-yl)-1H-1,8-naphthyridin-4-one;6-(8-chloro-2-methylquinolin-6-yl)-7-(1-methylpyrazol-3-yl)-1H-1,8-naphthyridin-4-one;6-(8-chloro-2-methylquinolin-6-yl)-7-(3-methylpyrazol-1-yl)-1H-1,8-naphthyridin-4-one;6-(8-chloro-3-methylquinolin-6-yl)-7-(1-methylpyrazol-3-yl)-1H-1,8-naphthyridin-4-one;6-(8-chloro-5-methylquinolin-6-yl)-7-(1-methylpyrazol-3-yl)-1H-1,8-naphthyridin-4-one;6-(8-chloro-5-methylquinolin-6-yl)-7-phenyl-1H-1,8-naphthyridin-2-one (CID 157399566) is 6-(8-chloro-4-fluoroquinolin-6-yl)-7-(1-methylpyrazol-3-yl)-1H-1,8-naphthyridin-4-one;6-(8-chloro-2-methylquinolin-6-yl)-7-(1-methylpyrazol-3-yl)-1H-1,8-naphthyridin-4-one;6-(8-chloro-2-methylquinolin-6-yl)-7-(3-methylpyrazol-1-yl)-1H-1,8-naphthyridin-4-one;6-(8-chloro-3-methylquinolin-6-yl)-7-(1-methylpyrazol-3-yl)-1H-1,8-naphthyridin-4-one;6-(8-chloro-5-methylquinolin-6-yl)-7-(1-methylpyrazol-3-yl)-1H-1,8-naphthyridin-4-one;6-(8-chloro-5-methylquinolin-6-yl)-7-phenyl-1H-1,8-naphthyridin-2-one.

What is the SMILES notation for 6-(8-chloro-4-fluoroquinolin-6-yl)-7-(1-methylpyrazol-3-yl)-1H-1,8-naphthyridin-4-one;6-(8-chloro-2-methylquinolin-6-yl)-7-(1-methylpyrazol-3-yl)-1H-1,8-naphthyridin-4-one;6-(8-chloro-2-methylquinolin-6-yl)-7-(3-methylpyrazol-1-yl)-1H-1,8-naphthyridin-4-one;6-(8-chloro-3-methylquinolin-6-yl)-7-(1-methylpyrazol-3-yl)-1H-1,8-naphthyridin-4-one;6-(8-chloro-5-methylquinolin-6-yl)-7-(1-methylpyrazol-3-yl)-1H-1,8-naphthyridin-4-one;6-(8-chloro-5-methylquinolin-6-yl)-7-phenyl-1H-1,8-naphthyridin-2-one?

The canonical SMILES for 6-(8-chloro-4-fluoroquinolin-6-yl)-7-(1-methylpyrazol-3-yl)-1H-1,8-naphthyridin-4-one;6-(8-chloro-2-methylquinolin-6-yl)-7-(1-methylpyrazol-3-yl)-1H-1,8-naphthyridin-4-one;6-(8-chloro-2-methylquinolin-6-yl)-7-(3-methylpyrazol-1-yl)-1H-1,8-naphthyridin-4-one;6-(8-chloro-3-methylquinolin-6-yl)-7-(1-methylpyrazol-3-yl)-1H-1,8-naphthyridin-4-one;6-(8-chloro-5-methylquinolin-6-yl)-7-(1-methylpyrazol-3-yl)-1H-1,8-naphthyridin-4-one;6-(8-chloro-5-methylquinolin-6-yl)-7-phenyl-1H-1,8-naphthyridin-2-one is Cc1c(-c2cc3c(=O)cc[nH]c3nc2-c2ccn(C)n2)cc(Cl)c2ncccc12.Cc1c(-c2cc3ccc(=O)[nH]c3nc2-c2ccccc2)cc(Cl)c2ncccc12.Cc1ccc2cc(-c3cc4c(=O)cc[nH]c4nc3-c3ccn(C)n3)cc(Cl)c2n1.Cc1ccc2cc(-c3cc4c(=O)cc[nH]c4nc3-n3ccc(C)n3)cc(Cl)c2n1.Cc1cnc2c(Cl)cc(-c3cc4c(=O)cc[nH]c4nc3-c3ccn(C)n3)cc2c1.Cn1ccc(-c2nc3[nH]ccc(=O)c3cc2-c2cc(Cl)c3nccc(F)c3c2)n1.

What is the InChIKey of 6-(8-chloro-4-fluoroquinolin-6-yl)-7-(1-methylpyrazol-3-yl)-1H-1,8-naphthyridin-4-one;6-(8-chloro-2-methylquinolin-6-yl)-7-(1-methylpyrazol-3-yl)-1H-1,8-naphthyridin-4-one;6-(8-chloro-2-methylquinolin-6-yl)-7-(3-methylpyrazol-1-yl)-1H-1,8-naphthyridin-4-one;6-(8-chloro-3-methylquinolin-6-yl)-7-(1-methylpyrazol-3-yl)-1H-1,8-naphthyridin-4-one;6-(8-chloro-5-methylquinolin-6-yl)-7-(1-methylpyrazol-3-yl)-1H-1,8-naphthyridin-4-one;6-(8-chloro-5-methylquinolin-6-yl)-7-phenyl-1H-1,8-naphthyridin-2-one?

The InChIKey is BMZDVMQJNDIIMK-UHFFFAOYSA-N. The full InChI is InChI=1S/C24H16ClN3O.4C22H16ClN5O.C21H13ClFN5O/c1-14-17-8-5-11-26-23(17)20(25)13-18(14)19-12-16-9-10-21(29)27-24(16)28-22(19)15-6-3-2-4-7-15;1-12-7-14-8-13(9-17(23)20(14)25-11-12)15-10-16-19(29)3-5-24-22(16)26-21(15)18-4-6-28(2)27-18;1-12-3-4-13-9-14(10-17(23)20(13)25-12)15-11-16-19(29)5-7-24-22(16)26-21(15)18-6-8-28(2)27-18;1-12-3-4-14-9-15(10-18(23)20(14)25-12)16-11-17-19(29)5-7-24-21(17)26-22(16)28-8-6-13(2)27-28;1-12-13-4-3-7-24-20(13)17(23)11-14(12)15-10-16-19(29)5-8-25-22(16)26-21(15)18-6-9-28(2)27-18;1-28-7-4-17(27-28)20-12(10-14-18(29)3-6-25-21(14)26-20)11-8-13-16(23)2-5-24-19(13)15(22)9-11/h2-13H,1H3,(H,27,28,29);3*3-11H,1-2H3,(H,24,26,29);3-11H,1-2H3,(H,25,26,29);2-10H,1H3,(H,25,26,29).

What are the key properties of 6-(8-chloro-4-fluoroquinolin-6-yl)-7-(1-methylpyrazol-3-yl)-1H-1,8-naphthyridin-4-one;6-(8-chloro-2-methylquinolin-6-yl)-7-(1-methylpyrazol-3-yl)-1H-1,8-naphthyridin-4-one;6-(8-chloro-2-methylquinolin-6-yl)-7-(3-methylpyrazol-1-yl)-1H-1,8-naphthyridin-4-one;6-(8-chloro-3-methylquinolin-6-yl)-7-(1-methylpyrazol-3-yl)-1H-1,8-naphthyridin-4-one;6-(8-chloro-5-methylquinolin-6-yl)-7-(1-methylpyrazol-3-yl)-1H-1,8-naphthyridin-4-one;6-(8-chloro-5-methylquinolin-6-yl)-7-phenyl-1H-1,8-naphthyridin-2-one?

6-(8-chloro-4-fluoroquinolin-6-yl)-7-(1-methylpyrazol-3-yl)-1H-1,8-naphthyridin-4-one;6-(8-chloro-2-methylquinolin-6-yl)-7-(1-methylpyrazol-3-yl)-1H-1,8-naphthyridin-4-one;6-(8-chloro-2-methylquinolin-6-yl)-7-(3-methylpyrazol-1-yl)-1H-1,8-naphthyridin-4-one;6-(8-chloro-3-methylquinolin-6-yl)-7-(1-methylpyrazol-3-yl)-1H-1,8-naphthyridin-4-one;6-(8-chloro-5-methylquinolin-6-yl)-7-(1-methylpyrazol-3-yl)-1H-1,8-naphthyridin-4-one;6-(8-chloro-5-methylquinolin-6-yl)-7-phenyl-1H-1,8-naphthyridin-2-one has a molecular weight of 2411.11 g/mol, XLogP of 28.19, 12 rotatable bonds, 6 hydrogen bond donors, and 28 hydrogen bond acceptors.

Where does this data come from?

All data for 6-(8-chloro-4-fluoroquinolin-6-yl)-7-(1-methylpyrazol-3-yl)-1H-1,8-naphthyridin-4-one;6-(8-chloro-2-methylquinolin-6-yl)-7-(1-methylpyrazol-3-yl)-1H-1,8-naphthyridin-4-one;6-(8-chloro-2-methylquinolin-6-yl)-7-(3-methylpyrazol-1-yl)-1H-1,8-naphthyridin-4-one;6-(8-chloro-3-methylquinolin-6-yl)-7-(1-methylpyrazol-3-yl)-1H-1,8-naphthyridin-4-one;6-(8-chloro-5-methylquinolin-6-yl)-7-(1-methylpyrazol-3-yl)-1H-1,8-naphthyridin-4-one;6-(8-chloro-5-methylquinolin-6-yl)-7-phenyl-1H-1,8-naphthyridin-2-one is sourced from PubChem (CID 157399566), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).