(2R,3R)-N-[[5-(2-chlorophenyl)-2-pyridinyl]methyl]-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-N-[[6-(2-chlorophenyl)-3-pyridinyl]methyl]-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-N-[[5-(2-cyanophenyl)-2-pyridinyl]methyl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-N-[[6-(5-cyanothiophen-2-yl)-3-pyridinyl]methyl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-N-[[6-(2,6-difluorophenyl)-3-pyridinyl]methyl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-N-[[6-[2-(methanesulfonamido)phenyl]-3-pyridinyl]methyl]-4-oxobutanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-N-[[5-(2-methoxyphenyl)-2-pyridinyl]methyl]-4-oxobutanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-N-[[6-(2-methoxyphenyl)-3-pyridinyl]methyl]-4-oxobutanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-N-[[6-(2-morpholin-4-ylphenyl)-3-pyridinyl]methyl]-4-oxobutanamide;2-[5-[[[(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxobutanoyl]amino]methyl]-2-pyridinyl]benzoic acid;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[[6-(2-phenylphenyl)-3-pyridinyl]methyl]butanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[(5-phenyl-2-pyridinyl)methyl]butanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[[6-[2-(trifluoromethoxy)phenyl]-3-pyridinyl]methyl]butanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-N-[[6-(3,5-dimethyl-1,2-oxazol-4-yl)-3-pyridinyl]methyl]-2,3-dihydroxy-4-oxobutanamide

C378H374Cl16F5N47O65S2 — CID 157413805

About (2R,3R)-N-[[5-(2-chlorophenyl)-2-pyridinyl]methyl]-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-N-[[6-(2-chlorophenyl)-3-pyridinyl]methyl]-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-N-[[5-(2-cyanophenyl)-2-pyridinyl]methyl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-N-[[6-(5-cyanothiophen-2-yl)-3-pyridinyl]methyl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-N-[[6-(2,6-difluorophenyl)-3-pyridinyl]methyl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-N-[[6-[2-(methanesulfonamido)phenyl]-3-pyridinyl]methyl]-4-oxobutanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-N-[[5-(2-methoxyphenyl)-2-pyridinyl]methyl]-4-oxobutanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-N-[[6-(2-methoxyphenyl)-3-pyridinyl]methyl]-4-oxobutanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-N-[[6-(2-morpholin-4-ylphenyl)-3-pyridinyl]methyl]-4-oxobutanamide;2-[5-[[[(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxobutanoyl]amino]methyl]-2-pyridinyl]benzoic acid;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[[6-(2-phenylphenyl)-3-pyridinyl]methyl]butanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[(5-phenyl-2-pyridinyl)methyl]butanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[[6-[2-(trifluoromethoxy)phenyl]-3-pyridinyl]methyl]butanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-N-[[6-(3,5-dimethyl-1,2-oxazol-4-yl)-3-pyridinyl]methyl]-2,3-dihydroxy-4-oxobutanamide

(2R,3R)-N-[[5-(2-chlorophenyl)-2-pyridinyl]methyl]-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-N-[[6-(2-chlorophenyl)-3-pyridinyl]methyl]-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-N-[[5-(2-cyanophenyl)-2-pyridinyl]methyl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-N-[[6-(5-cyanothiophen-2-yl)-3-pyridinyl]methyl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-N-[[6-(2,6-difluorophenyl)-3-pyridinyl]methyl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-N-[[6-[2-(methanesulfonamido)phenyl]-3-pyridinyl]methyl]-4-oxobutanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-N-[[5-(2-methoxyphenyl)-2-pyridinyl]methyl]-4-oxobutanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-N-[[6-(2-methoxyphenyl)-3-pyridinyl]methyl]-4-oxobutanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-N-[[6-(2-morpholin-4-ylphenyl)-3-pyridinyl]methyl]-4-oxobutanamide;2-[5-[[[(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxobutanoyl]amino]methyl]-2-pyridinyl]benzoic acid;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[[6-(2-phenylphenyl)-3-pyridinyl]methyl]butanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[(5-phenyl-2-pyridinyl)methyl]butanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[[6-[2-(trifluoromethoxy)phenyl]-3-pyridinyl]methyl]butanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-N-[[6-(3,5-dimethyl-1,2-oxazol-4-yl)-3-pyridinyl]methyl]-2,3-dihydroxy-4-oxobutanamide (PubChem CID 157413805) has the molecular formula C378H374Cl16F5N47O65S2 and a molecular weight of 7341.79 g/mol. Its IUPAC name is (2R,3R)-N-[[5-(2-chlorophenyl)-2-pyridinyl]methyl]-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-N-[[6-(2-chlorophenyl)-3-pyridinyl]methyl]-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-N-[[5-(2-cyanophenyl)-2-pyridinyl]methyl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-N-[[6-(5-cyanothiophen-2-yl)-3-pyridinyl]methyl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-N-[[6-(2,6-difluorophenyl)-3-pyridinyl]methyl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-N-[[6-[2-(methanesulfonamido)phenyl]-3-pyridinyl]methyl]-4-oxobutanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-N-[[5-(2-methoxyphenyl)-2-pyridinyl]methyl]-4-oxobutanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-N-[[6-(2-methoxyphenyl)-3-pyridinyl]methyl]-4-oxobutanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-N-[[6-(2-morpholin-4-ylphenyl)-3-pyridinyl]methyl]-4-oxobutanamide;2-[5-[[[(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxobutanoyl]amino]methyl]-2-pyridinyl]benzoic acid;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[[6-(2-phenylphenyl)-3-pyridinyl]methyl]butanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[(5-phenyl-2-pyridinyl)methyl]butanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[[6-[2-(trifluoromethoxy)phenyl]-3-pyridinyl]methyl]butanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-N-[[6-(3,5-dimethyl-1,2-oxazol-4-yl)-3-pyridinyl]methyl]-2,3-dihydroxy-4-oxobutanamide.

Molecular Properties

• Compound Name: (2R,3R)-N-[[5-(2-chlorophenyl)-2-pyridinyl]methyl]-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-N-[[6-(2-chlorophenyl)-3-pyridinyl]methyl]-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-N-[[5-(2-cyanophenyl)-2-pyridinyl]methyl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-N-[[6-(5-cyanothiophen-2-yl)-3-pyridinyl]methyl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-N-[[6-(2,6-difluorophenyl)-3-pyridinyl]methyl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-N-[[6-[2-(methanesulfonamido)phenyl]-3-pyridinyl]methyl]-4-oxobutanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-N-[[5-(2-methoxyphenyl)-2-pyridinyl]methyl]-4-oxobutanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-N-[[6-(2-methoxyphenyl)-3-pyridinyl]methyl]-4-oxobutanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-N-[[6-(2-morpholin-4-ylphenyl)-3-pyridinyl]methyl]-4-oxobutanamide;2-[5-[[[(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxobutanoyl]amino]methyl]-2-pyridinyl]benzoic acid;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[[6-(2-phenylphenyl)-3-pyridinyl]methyl]butanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[(5-phenyl-2-pyridinyl)methyl]butanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[[6-[2-(trifluoromethoxy)phenyl]-3-pyridinyl]methyl]butanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-N-[[6-(3,5-dimethyl-1,2-oxazol-4-yl)-3-pyridinyl]methyl]-2,3-dihydroxy-4-oxobutanamide
• PubChem CID: 157413805
• Molecular Formula: C378H374Cl16F5N47O65S2
• Molecular Weight: 7341.79 g/mol
• Exact Mass: 7329.18
• IUPAC Name: (2R,3R)-N-[[5-(2-chlorophenyl)-2-pyridinyl]methyl]-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-N-[[6-(2-chlorophenyl)-3-pyridinyl]methyl]-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-N-[[5-(2-cyanophenyl)-2-pyridinyl]methyl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-N-[[6-(5-cyanothiophen-2-yl)-3-pyridinyl]methyl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-N-[[6-(2,6-difluorophenyl)-3-pyridinyl]methyl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-N-[[6-[2-(methanesulfonamido)phenyl]-3-pyridinyl]methyl]-4-oxobutanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-N-[[5-(2-methoxyphenyl)-2-pyridinyl]methyl]-4-oxobutanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-N-[[6-(2-methoxyphenyl)-3-pyridinyl]methyl]-4-oxobutanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-N-[[6-(2-morpholin-4-ylphenyl)-3-pyridinyl]methyl]-4-oxobutanamide;2-[5-[[[(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxobutanoyl]amino]methyl]-2-pyridinyl]benzoic acid;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[[6-(2-phenylphenyl)-3-pyridinyl]methyl]butanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[(5-phenyl-2-pyridinyl)methyl]butanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[[6-[2-(trifluoromethoxy)phenyl]-3-pyridinyl]methyl]butanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-N-[[6-(3,5-dimethyl-1,2-oxazol-4-yl)-3-pyridinyl]methyl]-2,3-dihydroxy-4-oxobutanamide
• SMILES: COc1ccccc1-c1ccc(CNC(=O)[C@H](O)[C@@H](O)C(=O)N2CCCC2c2cccc(Cl)c2)cn1.COc1ccccc1-c1ccc(CNC(=O)[C@H](O)[C@@H](O)C(=O)N2CCCC2c2cccc(Cl)c2)nc1.CS(=O)(=O)Nc1ccccc1-c1ccc(CNC(=O)[C@H](O)[C@@H](O)C(=O)N2CCCC2c2cccc(Cl)c2)cn1.Cc1noc(C)c1-c1ccc(CNC(=O)[C@H](O)[C@@H](O)C(=O)N2CCCC2c2cccc(Cl)c2)cn1.N#Cc1ccc(-c2ccc(CNC(=O)[C@H](O)[C@@H](O)C(=O)N3CCCC3c3cccc(Cl)c3)cn2)s1.N#Cc1ccccc1-c1ccc(CNC(=O)[C@H](O)[C@@H](O)C(=O)N2CCCC2c2cccc(Cl)c2)nc1.O=C(NCc1ccc(-c2c(F)cccc2F)nc1)[C@H](O)[C@@H](O)C(=O)N1CCCC1c1cccc(Cl)c1.O=C(NCc1ccc(-c2ccccc2)cn1)[C@H](O)[C@@H](O)C(=O)N1CCCC1c1cccc(Cl)c1.O=C(NCc1ccc(-c2ccccc2-c2ccccc2)nc1)[C@H](O)[C@@H](O)C(=O)N1CCCC1c1cccc(Cl)c1.O=C(NCc1ccc(-c2ccccc2Cl)cn1)[C@H](O)[C@@H](O)C(=O)N1CCCC1c1cccc(Cl)c1.O=C(NCc1ccc(-c2ccccc2Cl)nc1)[C@H](O)[C@@H](O)C(=O)N1CCCC1c1cccc(Cl)c1.O=C(NCc1ccc(-c2ccccc2N2CCOCC2)nc1)[C@H](O)[C@@H](O)C(=O)N1CCCC1c1cccc(Cl)c1.O=C(NCc1ccc(-c2ccccc2OC(F)(F)F)nc1)[C@H](O)[C@@H](O)C(=O)N1CCCC1c1cccc(Cl)c1.O=C(O)c1ccccc1-c1ccc(CNC(=O)[C@H](O)[C@@H](O)C(=O)N2CCCC2c2cccc(Cl)c2)cn1
• InChI: InChI=1S/C32H30ClN3O4.C30H33ClN4O5.C27H25ClF3N3O5.C27H29ClN4O6S.C27H25ClN4O4.C27H26ClN3O6.2C27H28ClN3O5.2C26H25Cl2N3O4.C26H24ClF2N3O4.C26H26ClN3O4.C25H27ClN4O5.C25H23ClN4O4S/c33-24-11-6-10-23(18-24)28-14-7-17-36(28)32(40)30(38)29(37)31(39)35-20-21-15-16-27(34-19-21)26-13-5-4-12-25(26)22-8-2-1-3-9-22;31-22-6-3-5-21(17-22)25-9-4-12-35(25)30(39)28(37)27(36)29(38)33-19-20-10-11-24(32-18-20)23-7-1-2-8-26(23)34-13-15-40-16-14-34;28-18-6-3-5-17(13-18)21-8-4-12-34(21)26(38)24(36)23(35)25(37)33-15-16-10-11-20(32-14-16)19-7-1-2-9-22(19)39-27(29,30)31;1-39(37,38)31-22-9-3-2-8-20(22)21-12-11-17(15-29-21)16-30-26(35)24(33)25(34)27(36)32-13-5-10-23(32)18-6-4-7-19(28)14-18;28-20-7-3-6-17(13-20)23-9-4-12-32(23)27(36)25(34)24(33)26(35)31-16-21-11-10-19(15-30-21)22-8-2-1-5-18(22)14-29;28-18-6-3-5-17(13-18)22-9-4-12-31(22)26(35)24(33)23(32)25(34)30-15-16-10-11-21(29-14-16)19-7-1-2-8-20(19)27(36)37;1-36-23-10-3-2-8-20(23)21-12-11-17(15-29-21)16-30-26(34)24(32)25(33)27(35)31-13-5-9-22(31)18-6-4-7-19(28)14-18;1-36-23-10-3-2-8-21(23)18-11-12-20(29-15-18)16-30-26(34)24(32)25(33)27(35)31-13-5-9-22(31)17-6-4-7-19(28)14-17;27-18-6-3-5-17(13-18)22-9-4-12-31(22)26(35)24(33)23(32)25(34)30-15-16-10-11-21(29-14-16)19-7-1-2-8-20(19)28;27-18-6-3-5-16(13-18)22-9-4-12-31(22)26(35)24(33)23(32)25(34)30-15-19-11-10-17(14-29-19)20-7-1-2-8-21(20)28;27-17-5-1-4-16(12-17)21-8-3-11-32(21)26(36)24(34)23(33)25(35)31-14-15-9-10-20(30-13-15)22-18(28)6-2-7-19(22)29;27-20-9-4-8-18(14-20)22-10-5-13-30(22)26(34)24(32)23(31)25(33)29-16-21-12-11-19(15-28-21)17-6-2-1-3-7-17;1-14-21(15(2)35-29-14)19-9-8-16(12-27-19)13-28-24(33)22(31)23(32)25(34)30-10-4-7-20(30)17-5-3-6-18(26)11-17;26-17-4-1-3-16(11-17)20-5-2-10-30(20)25(34)23(32)22(31)24(33)29-14-15-6-8-19(28-13-15)21-9-7-18(12-27)35-21/h1-6,8-13,15-16,18-19,28-30,37-38H,7,14,17,20H2,(H,35,39);1-3,5-8,10-11,17-18,25,27-28,36-37H,4,9,12-16,19H2,(H,33,38);1-3,5-7,9-11,13-14,21,23-24,35-36H,4,8,12,15H2,(H,33,37);2-4,6-9,11-12,14-15,23-25,31,33-34H,5,10,13,16H2,1H3,(H,30,35);1-3,5-8,10-11,13,15,23-25,33-34H,4,9,12,16H2,(H,31,35);1-3,5-8,10-11,13-14,22-24,32-33H,4,9,12,15H2,(H,30,34)(H,36,37);2*2-4,6-8,10-12,14-15,22,24-25,32-33H,5,9,13,16H2,1H3,(H,30,34);2*1-3,5-8,10-11,13-14,22-24,32-33H,4,9,12,15H2,(H,30,34);1-2,4-7,9-10,12-13,21,23-24,33-34H,3,8,11,14H2,(H,31,35);1-4,6-9,11-12,14-15,22-24,31-32H,5,10,13,16H2,(H,29,33);3,5-6,8-9,11-12,20,22-23,31-32H,4,7,10,13H2,1-2H3,(H,28,33);1,3-4,6-9,11,13,20,22-23,31-32H,2,5,10,14H2,(H,29,33)/t28?,29-,30-;25?,27-,28-;21?,23-,24-;2*23?,24-,25-;22?,23-,24-;2*22?,24-,25-;2*22?,23-,24-;21?,23-,24-;22?,23-,24-;2*20?,22-,23-/m11111111111111/s1
• InChIKey: BOPHAYCWOYOKLQ-HDODXPCYSA-N
• XLogP: 45.94
• TPSA: 1635.88 Ų
• H-Bond Donors: 44
• H-Bond Acceptors: 83
• Rotatable Bonds: 106
• Heavy Atoms: 513
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	7341.79
LogP ≤ 5	45.94
H-Bond Donors ≤ 5	44
H-Bond Acceptors ≤ 10	83

Frequently Asked Questions

What is the IUPAC name of (2R,3R)-N-[[5-(2-chlorophenyl)-2-pyridinyl]methyl]-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-N-[[6-(2-chlorophenyl)-3-pyridinyl]methyl]-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-N-[[5-(2-cyanophenyl)-2-pyridinyl]methyl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-N-[[6-(5-cyanothiophen-2-yl)-3-pyridinyl]methyl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-N-[[6-(2,6-difluorophenyl)-3-pyridinyl]methyl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-N-[[6-[2-(methanesulfonamido)phenyl]-3-pyridinyl]methyl]-4-oxobutanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-N-[[5-(2-methoxyphenyl)-2-pyridinyl]methyl]-4-oxobutanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-N-[[6-(2-methoxyphenyl)-3-pyridinyl]methyl]-4-oxobutanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-N-[[6-(2-morpholin-4-ylphenyl)-3-pyridinyl]methyl]-4-oxobutanamide;2-[5-[[[(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxobutanoyl]amino]methyl]-2-pyridinyl]benzoic acid;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[[6-(2-phenylphenyl)-3-pyridinyl]methyl]butanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[(5-phenyl-2-pyridinyl)methyl]butanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[[6-[2-(trifluoromethoxy)phenyl]-3-pyridinyl]methyl]butanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-N-[[6-(3,5-dimethyl-1,2-oxazol-4-yl)-3-pyridinyl]methyl]-2,3-dihydroxy-4-oxobutanamide?

The IUPAC name of (2R,3R)-N-[[5-(2-chlorophenyl)-2-pyridinyl]methyl]-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-N-[[6-(2-chlorophenyl)-3-pyridinyl]methyl]-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-N-[[5-(2-cyanophenyl)-2-pyridinyl]methyl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-N-[[6-(5-cyanothiophen-2-yl)-3-pyridinyl]methyl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-N-[[6-(2,6-difluorophenyl)-3-pyridinyl]methyl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-N-[[6-[2-(methanesulfonamido)phenyl]-3-pyridinyl]methyl]-4-oxobutanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-N-[[5-(2-methoxyphenyl)-2-pyridinyl]methyl]-4-oxobutanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-N-[[6-(2-methoxyphenyl)-3-pyridinyl]methyl]-4-oxobutanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-N-[[6-(2-morpholin-4-ylphenyl)-3-pyridinyl]methyl]-4-oxobutanamide;2-[5-[[[(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxobutanoyl]amino]methyl]-2-pyridinyl]benzoic acid;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[[6-(2-phenylphenyl)-3-pyridinyl]methyl]butanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[(5-phenyl-2-pyridinyl)methyl]butanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[[6-[2-(trifluoromethoxy)phenyl]-3-pyridinyl]methyl]butanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-N-[[6-(3,5-dimethyl-1,2-oxazol-4-yl)-3-pyridinyl]methyl]-2,3-dihydroxy-4-oxobutanamide (CID 157413805) is (2R,3R)-N-[[5-(2-chlorophenyl)-2-pyridinyl]methyl]-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-N-[[6-(2-chlorophenyl)-3-pyridinyl]methyl]-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-N-[[5-(2-cyanophenyl)-2-pyridinyl]methyl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-N-[[6-(5-cyanothiophen-2-yl)-3-pyridinyl]methyl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-N-[[6-(2,6-difluorophenyl)-3-pyridinyl]methyl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-N-[[6-[2-(methanesulfonamido)phenyl]-3-pyridinyl]methyl]-4-oxobutanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-N-[[5-(2-methoxyphenyl)-2-pyridinyl]methyl]-4-oxobutanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-N-[[6-(2-methoxyphenyl)-3-pyridinyl]methyl]-4-oxobutanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-N-[[6-(2-morpholin-4-ylphenyl)-3-pyridinyl]methyl]-4-oxobutanamide;2-[5-[[[(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxobutanoyl]amino]methyl]-2-pyridinyl]benzoic acid;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[[6-(2-phenylphenyl)-3-pyridinyl]methyl]butanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[(5-phenyl-2-pyridinyl)methyl]butanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[[6-[2-(trifluoromethoxy)phenyl]-3-pyridinyl]methyl]butanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-N-[[6-(3,5-dimethyl-1,2-oxazol-4-yl)-3-pyridinyl]methyl]-2,3-dihydroxy-4-oxobutanamide.

What is the SMILES notation for (2R,3R)-N-[[5-(2-chlorophenyl)-2-pyridinyl]methyl]-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-N-[[6-(2-chlorophenyl)-3-pyridinyl]methyl]-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-N-[[5-(2-cyanophenyl)-2-pyridinyl]methyl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-N-[[6-(5-cyanothiophen-2-yl)-3-pyridinyl]methyl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-N-[[6-(2,6-difluorophenyl)-3-pyridinyl]methyl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-N-[[6-[2-(methanesulfonamido)phenyl]-3-pyridinyl]methyl]-4-oxobutanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-N-[[5-(2-methoxyphenyl)-2-pyridinyl]methyl]-4-oxobutanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-N-[[6-(2-methoxyphenyl)-3-pyridinyl]methyl]-4-oxobutanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-N-[[6-(2-morpholin-4-ylphenyl)-3-pyridinyl]methyl]-4-oxobutanamide;2-[5-[[[(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxobutanoyl]amino]methyl]-2-pyridinyl]benzoic acid;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[[6-(2-phenylphenyl)-3-pyridinyl]methyl]butanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[(5-phenyl-2-pyridinyl)methyl]butanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[[6-[2-(trifluoromethoxy)phenyl]-3-pyridinyl]methyl]butanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-N-[[6-(3,5-dimethyl-1,2-oxazol-4-yl)-3-pyridinyl]methyl]-2,3-dihydroxy-4-oxobutanamide?

The canonical SMILES for (2R,3R)-N-[[5-(2-chlorophenyl)-2-pyridinyl]methyl]-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-N-[[6-(2-chlorophenyl)-3-pyridinyl]methyl]-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-N-[[5-(2-cyanophenyl)-2-pyridinyl]methyl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-N-[[6-(5-cyanothiophen-2-yl)-3-pyridinyl]methyl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-N-[[6-(2,6-difluorophenyl)-3-pyridinyl]methyl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-N-[[6-[2-(methanesulfonamido)phenyl]-3-pyridinyl]methyl]-4-oxobutanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-N-[[5-(2-methoxyphenyl)-2-pyridinyl]methyl]-4-oxobutanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-N-[[6-(2-methoxyphenyl)-3-pyridinyl]methyl]-4-oxobutanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-N-[[6-(2-morpholin-4-ylphenyl)-3-pyridinyl]methyl]-4-oxobutanamide;2-[5-[[[(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxobutanoyl]amino]methyl]-2-pyridinyl]benzoic acid;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[[6-(2-phenylphenyl)-3-pyridinyl]methyl]butanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[(5-phenyl-2-pyridinyl)methyl]butanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[[6-[2-(trifluoromethoxy)phenyl]-3-pyridinyl]methyl]butanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-N-[[6-(3,5-dimethyl-1,2-oxazol-4-yl)-3-pyridinyl]methyl]-2,3-dihydroxy-4-oxobutanamide is COc1ccccc1-c1ccc(CNC(=O)[C@H](O)[C@@H](O)C(=O)N2CCCC2c2cccc(Cl)c2)cn1.COc1ccccc1-c1ccc(CNC(=O)[C@H](O)[C@@H](O)C(=O)N2CCCC2c2cccc(Cl)c2)nc1.CS(=O)(=O)Nc1ccccc1-c1ccc(CNC(=O)[C@H](O)[C@@H](O)C(=O)N2CCCC2c2cccc(Cl)c2)cn1.Cc1noc(C)c1-c1ccc(CNC(=O)[C@H](O)[C@@H](O)C(=O)N2CCCC2c2cccc(Cl)c2)cn1.N#Cc1ccc(-c2ccc(CNC(=O)[C@H](O)[C@@H](O)C(=O)N3CCCC3c3cccc(Cl)c3)cn2)s1.N#Cc1ccccc1-c1ccc(CNC(=O)[C@H](O)[C@@H](O)C(=O)N2CCCC2c2cccc(Cl)c2)nc1.O=C(NCc1ccc(-c2c(F)cccc2F)nc1)[C@H](O)[C@@H](O)C(=O)N1CCCC1c1cccc(Cl)c1.O=C(NCc1ccc(-c2ccccc2)cn1)[C@H](O)[C@@H](O)C(=O)N1CCCC1c1cccc(Cl)c1.O=C(NCc1ccc(-c2ccccc2-c2ccccc2)nc1)[C@H](O)[C@@H](O)C(=O)N1CCCC1c1cccc(Cl)c1.O=C(NCc1ccc(-c2ccccc2Cl)cn1)[C@H](O)[C@@H](O)C(=O)N1CCCC1c1cccc(Cl)c1.O=C(NCc1ccc(-c2ccccc2Cl)nc1)[C@H](O)[C@@H](O)C(=O)N1CCCC1c1cccc(Cl)c1.O=C(NCc1ccc(-c2ccccc2N2CCOCC2)nc1)[C@H](O)[C@@H](O)C(=O)N1CCCC1c1cccc(Cl)c1.O=C(NCc1ccc(-c2ccccc2OC(F)(F)F)nc1)[C@H](O)[C@@H](O)C(=O)N1CCCC1c1cccc(Cl)c1.O=C(O)c1ccccc1-c1ccc(CNC(=O)[C@H](O)[C@@H](O)C(=O)N2CCCC2c2cccc(Cl)c2)cn1.

What is the InChIKey of (2R,3R)-N-[[5-(2-chlorophenyl)-2-pyridinyl]methyl]-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-N-[[6-(2-chlorophenyl)-3-pyridinyl]methyl]-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-N-[[5-(2-cyanophenyl)-2-pyridinyl]methyl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-N-[[6-(5-cyanothiophen-2-yl)-3-pyridinyl]methyl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-N-[[6-(2,6-difluorophenyl)-3-pyridinyl]methyl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-N-[[6-[2-(methanesulfonamido)phenyl]-3-pyridinyl]methyl]-4-oxobutanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-N-[[5-(2-methoxyphenyl)-2-pyridinyl]methyl]-4-oxobutanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-N-[[6-(2-methoxyphenyl)-3-pyridinyl]methyl]-4-oxobutanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-N-[[6-(2-morpholin-4-ylphenyl)-3-pyridinyl]methyl]-4-oxobutanamide;2-[5-[[[(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxobutanoyl]amino]methyl]-2-pyridinyl]benzoic acid;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[[6-(2-phenylphenyl)-3-pyridinyl]methyl]butanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[(5-phenyl-2-pyridinyl)methyl]butanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[[6-[2-(trifluoromethoxy)phenyl]-3-pyridinyl]methyl]butanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-N-[[6-(3,5-dimethyl-1,2-oxazol-4-yl)-3-pyridinyl]methyl]-2,3-dihydroxy-4-oxobutanamide?

The InChIKey is BOPHAYCWOYOKLQ-HDODXPCYSA-N. The full InChI is InChI=1S/C32H30ClN3O4.C30H33ClN4O5.C27H25ClF3N3O5.C27H29ClN4O6S.C27H25ClN4O4.C27H26ClN3O6.2C27H28ClN3O5.2C26H25Cl2N3O4.C26H24ClF2N3O4.C26H26ClN3O4.C25H27ClN4O5.C25H23ClN4O4S/c33-24-11-6-10-23(18-24)28-14-7-17-36(28)32(40)30(38)29(37)31(39)35-20-21-15-16-27(34-19-21)26-13-5-4-12-25(26)22-8-2-1-3-9-22;31-22-6-3-5-21(17-22)25-9-4-12-35(25)30(39)28(37)27(36)29(38)33-19-20-10-11-24(32-18-20)23-7-1-2-8-26(23)34-13-15-40-16-14-34;28-18-6-3-5-17(13-18)21-8-4-12-34(21)26(38)24(36)23(35)25(37)33-15-16-10-11-20(32-14-16)19-7-1-2-9-22(19)39-27(29,30)31;1-39(37,38)31-22-9-3-2-8-20(22)21-12-11-17(15-29-21)16-30-26(35)24(33)25(34)27(36)32-13-5-10-23(32)18-6-4-7-19(28)14-18;28-20-7-3-6-17(13-20)23-9-4-12-32(23)27(36)25(34)24(33)26(35)31-16-21-11-10-19(15-30-21)22-8-2-1-5-18(22)14-29;28-18-6-3-5-17(13-18)22-9-4-12-31(22)26(35)24(33)23(32)25(34)30-15-16-10-11-21(29-14-16)19-7-1-2-8-20(19)27(36)37;1-36-23-10-3-2-8-20(23)21-12-11-17(15-29-21)16-30-26(34)24(32)25(33)27(35)31-13-5-9-22(31)18-6-4-7-19(28)14-18;1-36-23-10-3-2-8-21(23)18-11-12-20(29-15-18)16-30-26(34)24(32)25(33)27(35)31-13-5-9-22(31)17-6-4-7-19(28)14-17;27-18-6-3-5-17(13-18)22-9-4-12-31(22)26(35)24(33)23(32)25(34)30-15-16-10-11-21(29-14-16)19-7-1-2-8-20(19)28;27-18-6-3-5-16(13-18)22-9-4-12-31(22)26(35)24(33)23(32)25(34)30-15-19-11-10-17(14-29-19)20-7-1-2-8-21(20)28;27-17-5-1-4-16(12-17)21-8-3-11-32(21)26(36)24(34)23(33)25(35)31-14-15-9-10-20(30-13-15)22-18(28)6-2-7-19(22)29;27-20-9-4-8-18(14-20)22-10-5-13-30(22)26(34)24(32)23(31)25(33)29-16-21-12-11-19(15-28-21)17-6-2-1-3-7-17;1-14-21(15(2)35-29-14)19-9-8-16(12-27-19)13-28-24(33)22(31)23(32)25(34)30-10-4-7-20(30)17-5-3-6-18(26)11-17;26-17-4-1-3-16(11-17)20-5-2-10-30(20)25(34)23(32)22(31)24(33)29-14-15-6-8-19(28-13-15)21-9-7-18(12-27)35-21/h1-6,8-13,15-16,18-19,28-30,37-38H,7,14,17,20H2,(H,35,39);1-3,5-8,10-11,17-18,25,27-28,36-37H,4,9,12-16,19H2,(H,33,38);1-3,5-7,9-11,13-14,21,23-24,35-36H,4,8,12,15H2,(H,33,37);2-4,6-9,11-12,14-15,23-25,31,33-34H,5,10,13,16H2,1H3,(H,30,35);1-3,5-8,10-11,13,15,23-25,33-34H,4,9,12,16H2,(H,31,35);1-3,5-8,10-11,13-14,22-24,32-33H,4,9,12,15H2,(H,30,34)(H,36,37);2*2-4,6-8,10-12,14-15,22,24-25,32-33H,5,9,13,16H2,1H3,(H,30,34);2*1-3,5-8,10-11,13-14,22-24,32-33H,4,9,12,15H2,(H,30,34);1-2,4-7,9-10,12-13,21,23-24,33-34H,3,8,11,14H2,(H,31,35);1-4,6-9,11-12,14-15,22-24,31-32H,5,10,13,16H2,(H,29,33);3,5-6,8-9,11-12,20,22-23,31-32H,4,7,10,13H2,1-2H3,(H,28,33);1,3-4,6-9,11,13,20,22-23,31-32H,2,5,10,14H2,(H,29,33)/t28?,29-,30-;25?,27-,28-;21?,23-,24-;2*23?,24-,25-;22?,23-,24-;2*22?,24-,25-;2*22?,23-,24-;21?,23-,24-;22?,23-,24-;2*20?,22-,23-/m11111111111111/s1.

What are the key properties of (2R,3R)-N-[[5-(2-chlorophenyl)-2-pyridinyl]methyl]-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-N-[[6-(2-chlorophenyl)-3-pyridinyl]methyl]-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-N-[[5-(2-cyanophenyl)-2-pyridinyl]methyl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-N-[[6-(5-cyanothiophen-2-yl)-3-pyridinyl]methyl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-N-[[6-(2,6-difluorophenyl)-3-pyridinyl]methyl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-N-[[6-[2-(methanesulfonamido)phenyl]-3-pyridinyl]methyl]-4-oxobutanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-N-[[5-(2-methoxyphenyl)-2-pyridinyl]methyl]-4-oxobutanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-N-[[6-(2-methoxyphenyl)-3-pyridinyl]methyl]-4-oxobutanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-N-[[6-(2-morpholin-4-ylphenyl)-3-pyridinyl]methyl]-4-oxobutanamide;2-[5-[[[(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxobutanoyl]amino]methyl]-2-pyridinyl]benzoic acid;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[[6-(2-phenylphenyl)-3-pyridinyl]methyl]butanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[(5-phenyl-2-pyridinyl)methyl]butanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[[6-[2-(trifluoromethoxy)phenyl]-3-pyridinyl]methyl]butanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-N-[[6-(3,5-dimethyl-1,2-oxazol-4-yl)-3-pyridinyl]methyl]-2,3-dihydroxy-4-oxobutanamide?

(2R,3R)-N-[[5-(2-chlorophenyl)-2-pyridinyl]methyl]-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-N-[[6-(2-chlorophenyl)-3-pyridinyl]methyl]-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-N-[[5-(2-cyanophenyl)-2-pyridinyl]methyl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-N-[[6-(5-cyanothiophen-2-yl)-3-pyridinyl]methyl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-N-[[6-(2,6-difluorophenyl)-3-pyridinyl]methyl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-N-[[6-[2-(methanesulfonamido)phenyl]-3-pyridinyl]methyl]-4-oxobutanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-N-[[5-(2-methoxyphenyl)-2-pyridinyl]methyl]-4-oxobutanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-N-[[6-(2-methoxyphenyl)-3-pyridinyl]methyl]-4-oxobutanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-N-[[6-(2-morpholin-4-ylphenyl)-3-pyridinyl]methyl]-4-oxobutanamide;2-[5-[[[(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxobutanoyl]amino]methyl]-2-pyridinyl]benzoic acid;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[[6-(2-phenylphenyl)-3-pyridinyl]methyl]butanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[(5-phenyl-2-pyridinyl)methyl]butanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[[6-[2-(trifluoromethoxy)phenyl]-3-pyridinyl]methyl]butanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-N-[[6-(3,5-dimethyl-1,2-oxazol-4-yl)-3-pyridinyl]methyl]-2,3-dihydroxy-4-oxobutanamide has a molecular weight of 7341.79 g/mol, XLogP of 45.94, 106 rotatable bonds, 44 hydrogen bond donors, and 83 hydrogen bond acceptors.

Where does this data come from?

All data for (2R,3R)-N-[[5-(2-chlorophenyl)-2-pyridinyl]methyl]-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-N-[[6-(2-chlorophenyl)-3-pyridinyl]methyl]-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-N-[[5-(2-cyanophenyl)-2-pyridinyl]methyl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-N-[[6-(5-cyanothiophen-2-yl)-3-pyridinyl]methyl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-N-[[6-(2,6-difluorophenyl)-3-pyridinyl]methyl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-N-[[6-[2-(methanesulfonamido)phenyl]-3-pyridinyl]methyl]-4-oxobutanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-N-[[5-(2-methoxyphenyl)-2-pyridinyl]methyl]-4-oxobutanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-N-[[6-(2-methoxyphenyl)-3-pyridinyl]methyl]-4-oxobutanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-N-[[6-(2-morpholin-4-ylphenyl)-3-pyridinyl]methyl]-4-oxobutanamide;2-[5-[[[(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxobutanoyl]amino]methyl]-2-pyridinyl]benzoic acid;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[[6-(2-phenylphenyl)-3-pyridinyl]methyl]butanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[(5-phenyl-2-pyridinyl)methyl]butanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[[6-[2-(trifluoromethoxy)phenyl]-3-pyridinyl]methyl]butanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-N-[[6-(3,5-dimethyl-1,2-oxazol-4-yl)-3-pyridinyl]methyl]-2,3-dihydroxy-4-oxobutanamide is sourced from PubChem (CID 157413805), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).