8-(2,5-dimethylpyrazol-3-yl)-N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methylimidazo[1,2-c]pyrimidin-5-amine;N-[(5-fluoro-1-benzofuran-4-yl)methyl]-2-methyl-8-(2-methyl-3-pyridinyl)imidazo[1,2-c]pyrimidin-5-amine;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methyl-8-(4-methylimidazol-1-yl)imidazo[1,2-c]pyrimidin-5-amine;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methyl-8-(2-methyl-3-pyridinyl)imidazo[1,2-c]pyrimidin-5-amine

C85H78F4N22O4 — CID 157430428

About 8-(2,5-dimethylpyrazol-3-yl)-N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methylimidazo[1,2-c]pyrimidin-5-amine;N-[(5-fluoro-1-benzofuran-4-yl)methyl]-2-methyl-8-(2-methyl-3-pyridinyl)imidazo[1,2-c]pyrimidin-5-amine;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methyl-8-(4-methylimidazol-1-yl)imidazo[1,2-c]pyrimidin-5-amine;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methyl-8-(2-methyl-3-pyridinyl)imidazo[1,2-c]pyrimidin-5-amine

8-(2,5-dimethylpyrazol-3-yl)-N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methylimidazo[1,2-c]pyrimidin-5-amine;N-[(5-fluoro-1-benzofuran-4-yl)methyl]-2-methyl-8-(2-methyl-3-pyridinyl)imidazo[1,2-c]pyrimidin-5-amine;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methyl-8-(4-methylimidazol-1-yl)imidazo[1,2-c]pyrimidin-5-amine;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methyl-8-(2-methyl-3-pyridinyl)imidazo[1,2-c]pyrimidin-5-amine (PubChem CID 157430428) has the molecular formula C85H78F4N22O4 and a molecular weight of 1547.70 g/mol. Its IUPAC name is 8-(2,5-dimethylpyrazol-3-yl)-N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methylimidazo[1,2-c]pyrimidin-5-amine;N-[(5-fluoro-1-benzofuran-4-yl)methyl]-2-methyl-8-(2-methyl-3-pyridinyl)imidazo[1,2-c]pyrimidin-5-amine;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methyl-8-(4-methylimidazol-1-yl)imidazo[1,2-c]pyrimidin-5-amine;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methyl-8-(2-methyl-3-pyridinyl)imidazo[1,2-c]pyrimidin-5-amine.

Molecular Properties

• Compound Name: 8-(2,5-dimethylpyrazol-3-yl)-N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methylimidazo[1,2-c]pyrimidin-5-amine;N-[(5-fluoro-1-benzofuran-4-yl)methyl]-2-methyl-8-(2-methyl-3-pyridinyl)imidazo[1,2-c]pyrimidin-5-amine;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methyl-8-(4-methylimidazol-1-yl)imidazo[1,2-c]pyrimidin-5-amine;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methyl-8-(2-methyl-3-pyridinyl)imidazo[1,2-c]pyrimidin-5-amine
• PubChem CID: 157430428
• Molecular Formula: C85H78F4N22O4
• Molecular Weight: 1547.70 g/mol
• Exact Mass: 1546.65
• IUPAC Name: 8-(2,5-dimethylpyrazol-3-yl)-N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methylimidazo[1,2-c]pyrimidin-5-amine;N-[(5-fluoro-1-benzofuran-4-yl)methyl]-2-methyl-8-(2-methyl-3-pyridinyl)imidazo[1,2-c]pyrimidin-5-amine;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methyl-8-(4-methylimidazol-1-yl)imidazo[1,2-c]pyrimidin-5-amine;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methyl-8-(2-methyl-3-pyridinyl)imidazo[1,2-c]pyrimidin-5-amine
• SMILES: Cc1cn(-c2cnc(NCc3c(F)ccc4c3CCO4)n3cc(C)nc23)cn1.Cc1cn2c(NCc3c(F)ccc4c3CCO4)ncc(-c3cc(C)nn3C)c2n1.Cc1cn2c(NCc3c(F)ccc4c3CCO4)ncc(-c3cccnc3C)c2n1.Cc1cn2c(NCc3c(F)ccc4occc34)ncc(-c3cccnc3C)c2n1
• InChI: InChI=1S/C22H20FN5O.C22H18FN5O.C21H21FN6O.C20H19FN6O/c2*1-13-12-28-21(27-13)18(15-4-3-8-24-14(15)2)11-26-22(28)25-10-17-16-7-9-29-20(16)6-5-19(17)23;1-12-8-18(27(3)26-12)16-10-24-21(28-11-13(2)25-20(16)28)23-9-15-14-6-7-29-19(14)5-4-17(15)22;1-12-9-26(11-24-12)17-8-23-20(27-10-13(2)25-19(17)27)22-7-15-14-5-6-28-18(14)4-3-16(15)21/h3-6,8,11-12H,7,9-10H2,1-2H3,(H,25,26);3-9,11-12H,10H2,1-2H3,(H,25,26);4-5,8,10-11H,6-7,9H2,1-3H3,(H,23,24);3-4,8-11H,5-7H2,1-2H3,(H,22,23)
• InChIKey: BQLRSHFJZAIZAG-UHFFFAOYSA-N
• XLogP: 15.65
• TPSA: 271.13 Ų
• H-Bond Donors: 4
• H-Bond Acceptors: 26
• Rotatable Bonds: 16
• Heavy Atoms: 115
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	1547.70
LogP ≤ 5	15.65
H-Bond Donors ≤ 5	4
H-Bond Acceptors ≤ 10	26

Frequently Asked Questions

What is the IUPAC name of 8-(2,5-dimethylpyrazol-3-yl)-N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methylimidazo[1,2-c]pyrimidin-5-amine;N-[(5-fluoro-1-benzofuran-4-yl)methyl]-2-methyl-8-(2-methyl-3-pyridinyl)imidazo[1,2-c]pyrimidin-5-amine;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methyl-8-(4-methylimidazol-1-yl)imidazo[1,2-c]pyrimidin-5-amine;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methyl-8-(2-methyl-3-pyridinyl)imidazo[1,2-c]pyrimidin-5-amine?

The IUPAC name of 8-(2,5-dimethylpyrazol-3-yl)-N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methylimidazo[1,2-c]pyrimidin-5-amine;N-[(5-fluoro-1-benzofuran-4-yl)methyl]-2-methyl-8-(2-methyl-3-pyridinyl)imidazo[1,2-c]pyrimidin-5-amine;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methyl-8-(4-methylimidazol-1-yl)imidazo[1,2-c]pyrimidin-5-amine;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methyl-8-(2-methyl-3-pyridinyl)imidazo[1,2-c]pyrimidin-5-amine (CID 157430428) is 8-(2,5-dimethylpyrazol-3-yl)-N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methylimidazo[1,2-c]pyrimidin-5-amine;N-[(5-fluoro-1-benzofuran-4-yl)methyl]-2-methyl-8-(2-methyl-3-pyridinyl)imidazo[1,2-c]pyrimidin-5-amine;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methyl-8-(4-methylimidazol-1-yl)imidazo[1,2-c]pyrimidin-5-amine;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methyl-8-(2-methyl-3-pyridinyl)imidazo[1,2-c]pyrimidin-5-amine.

What is the SMILES notation for 8-(2,5-dimethylpyrazol-3-yl)-N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methylimidazo[1,2-c]pyrimidin-5-amine;N-[(5-fluoro-1-benzofuran-4-yl)methyl]-2-methyl-8-(2-methyl-3-pyridinyl)imidazo[1,2-c]pyrimidin-5-amine;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methyl-8-(4-methylimidazol-1-yl)imidazo[1,2-c]pyrimidin-5-amine;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methyl-8-(2-methyl-3-pyridinyl)imidazo[1,2-c]pyrimidin-5-amine?

The canonical SMILES for 8-(2,5-dimethylpyrazol-3-yl)-N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methylimidazo[1,2-c]pyrimidin-5-amine;N-[(5-fluoro-1-benzofuran-4-yl)methyl]-2-methyl-8-(2-methyl-3-pyridinyl)imidazo[1,2-c]pyrimidin-5-amine;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methyl-8-(4-methylimidazol-1-yl)imidazo[1,2-c]pyrimidin-5-amine;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methyl-8-(2-methyl-3-pyridinyl)imidazo[1,2-c]pyrimidin-5-amine is Cc1cn(-c2cnc(NCc3c(F)ccc4c3CCO4)n3cc(C)nc23)cn1.Cc1cn2c(NCc3c(F)ccc4c3CCO4)ncc(-c3cc(C)nn3C)c2n1.Cc1cn2c(NCc3c(F)ccc4c3CCO4)ncc(-c3cccnc3C)c2n1.Cc1cn2c(NCc3c(F)ccc4occc34)ncc(-c3cccnc3C)c2n1.

What is the InChIKey of 8-(2,5-dimethylpyrazol-3-yl)-N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methylimidazo[1,2-c]pyrimidin-5-amine;N-[(5-fluoro-1-benzofuran-4-yl)methyl]-2-methyl-8-(2-methyl-3-pyridinyl)imidazo[1,2-c]pyrimidin-5-amine;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methyl-8-(4-methylimidazol-1-yl)imidazo[1,2-c]pyrimidin-5-amine;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methyl-8-(2-methyl-3-pyridinyl)imidazo[1,2-c]pyrimidin-5-amine?

The InChIKey is BQLRSHFJZAIZAG-UHFFFAOYSA-N. The full InChI is InChI=1S/C22H20FN5O.C22H18FN5O.C21H21FN6O.C20H19FN6O/c2*1-13-12-28-21(27-13)18(15-4-3-8-24-14(15)2)11-26-22(28)25-10-17-16-7-9-29-20(16)6-5-19(17)23;1-12-8-18(27(3)26-12)16-10-24-21(28-11-13(2)25-20(16)28)23-9-15-14-6-7-29-19(14)5-4-17(15)22;1-12-9-26(11-24-12)17-8-23-20(27-10-13(2)25-19(17)27)22-7-15-14-5-6-28-18(14)4-3-16(15)21/h3-6,8,11-12H,7,9-10H2,1-2H3,(H,25,26);3-9,11-12H,10H2,1-2H3,(H,25,26);4-5,8,10-11H,6-7,9H2,1-3H3,(H,23,24);3-4,8-11H,5-7H2,1-2H3,(H,22,23).

What are the key properties of 8-(2,5-dimethylpyrazol-3-yl)-N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methylimidazo[1,2-c]pyrimidin-5-amine;N-[(5-fluoro-1-benzofuran-4-yl)methyl]-2-methyl-8-(2-methyl-3-pyridinyl)imidazo[1,2-c]pyrimidin-5-amine;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methyl-8-(4-methylimidazol-1-yl)imidazo[1,2-c]pyrimidin-5-amine;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methyl-8-(2-methyl-3-pyridinyl)imidazo[1,2-c]pyrimidin-5-amine?

8-(2,5-dimethylpyrazol-3-yl)-N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methylimidazo[1,2-c]pyrimidin-5-amine;N-[(5-fluoro-1-benzofuran-4-yl)methyl]-2-methyl-8-(2-methyl-3-pyridinyl)imidazo[1,2-c]pyrimidin-5-amine;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methyl-8-(4-methylimidazol-1-yl)imidazo[1,2-c]pyrimidin-5-amine;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methyl-8-(2-methyl-3-pyridinyl)imidazo[1,2-c]pyrimidin-5-amine has a molecular weight of 1547.70 g/mol, XLogP of 15.65, 16 rotatable bonds, 4 hydrogen bond donors, and 26 hydrogen bond acceptors.

Where does this data come from?

All data for 8-(2,5-dimethylpyrazol-3-yl)-N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methylimidazo[1,2-c]pyrimidin-5-amine;N-[(5-fluoro-1-benzofuran-4-yl)methyl]-2-methyl-8-(2-methyl-3-pyridinyl)imidazo[1,2-c]pyrimidin-5-amine;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methyl-8-(4-methylimidazol-1-yl)imidazo[1,2-c]pyrimidin-5-amine;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methyl-8-(2-methyl-3-pyridinyl)imidazo[1,2-c]pyrimidin-5-amine is sourced from PubChem (CID 157430428), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).